EX-4.2





 Exhibit 4.2 

EXECUTION VERSION 

DH EUROPE FINANCE II S.À R.L., 

as Issuer 
 DANAHER
CORPORATION, 
 as Guarantor 

AND 
 THE BANK OF NEW
YORK MELLON TRUST COMPANY, N.A., 
 as Trustee 
  

 
 SECOND
SUPPLEMENTAL INDENTURE 
 2.050% Senior Notes Due 2022 

2.200% Senior Notes Due 2024 

2.600% Senior Notes Due 2029 

3.250% Senior Notes Due 2039 

3.400% Senior Notes Due 2049 

Dated as of November 7, 2019 
  

 
  












 THIS SECOND SUPPLEMENTAL INDENTURE (this “Supplemental
Indenture”), dated as November 7, 2019, is among DH EUROPE FINANCE II S.À R.L., a private limited liability company, société à responsabilité limitée, duly organized and existing under
the laws of Luxembourg (the “Company”), having its registered office at 1B Heienhaff, L-1736 Senningerberg, Grand Duchy of Luxembourg and registered with the Luxembourg Trade and Companies
Register under number B 235.237, DANAHER CORPORATION, a corporation duly organized and existing under the laws of the State of Delaware (the “Guarantor”) and the indirect parent company of the Company, having its principal office at
2200 Pennsylvania Avenue, N.W., Suite 800W, Washington, D.C. 20037-1701, and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., a national banking association duly organized and existing under the laws of the United States of America, as Trustee (the
“Trustee”). 
 RECITALS 

WHEREAS, the Company and the Guarantor have heretofore executed and delivered to the Trustee an Indenture dated as of
September 18, 2019, among the Company, the Guarantor and the Trustee (the “Base Indenture,” and together with this Supplemental Indenture, the “Indenture”), providing for the issuance from time to time of
series of the Company’s Securities and Guarantees of such Securities by the Guarantor; 
 WHEREAS, Section 901(g)
of the Base Indenture provides for the Company, the Guarantor and the Trustee to enter into an indenture supplemental to the Base Indenture to establish the form or terms of Securities of any series as permitted by Section 201 and
Section 301 of the Base Indenture; 
 WHEREAS, pursuant to Section 301 of the Base Indenture, the Company wishes
to provide for the issuance of five (5) new series of Securities to be known as its: (a) 2.050% Senior Notes due 2022 (the “2022 Notes”), (b) 2.200% Senior Notes due 2024 (the “2024 Notes”), (c) 2.600% Senior
Notes due 2029 (the “2029 Notes”), (d) 3.250% Senior Notes due 2039 (the “2039 Notes”) and (e) 3.400% Senior Notes due 2049 (the “2049 Notes,” and collectively with the 2022 Notes, the 2024 Notes,
the 2029 Notes and the 2039 Notes, the “Notes”). The forms of the Notes of each such series and the terms, provisions and conditions thereof shall be as set forth in this Supplemental Indenture; 

WHEREAS, the Guarantor desires to Guarantee each series of Notes on the terms set forth in Article 14 of the Base Indenture;
and 
 WHEREAS, the Company and the Guarantor have requested that the Trustee execute and deliver this Supplemental
Indenture, and all requirements necessary to make this Supplemental Indenture a valid and binding instrument enforceable in accordance with its terms, to make each series of Notes, when executed and delivered by the Company and authenticated by the
Trustee, the valid, binding and enforceable obligations of the Company, and to make the Guarantees of each series of Notes, when such series of Notes have been executed and delivered by the Company and authenticated by the Trustee, and when the
notations of Guarantee to be attached to each Note are executed and delivered by the Guarantor, the valid, binding and enforceable obligations of the Guarantor, in each case, have been done and performed, and the execution and delivery of this
Supplemental Indenture has been duly authorized in all respects; 

  
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 NOW, THEREFORE, in consideration of the covenants and agreements set forth
herein and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 

ARTICLE I 
 DEFINITIONS 

Section 1.01 Relation to Base Indenture. This Supplemental Indenture constitutes an integral part of the Base
Indenture. 
 Section 1.02 Definition of Terms. For all purposes of this Supplemental Indenture: 

(a) capitalized terms used herein without definition shall have the meanings set forth in the Base Indenture; 

(b) a term defined anywhere in this Supplemental Indenture has the same meaning throughout and, to the extent any such
term conflicts with a corresponding term defined in the Base Indenture or is otherwise set forth both in this Supplemental Indenture and in the Base Indenture, such term as defined in this Supplemental Indenture shall supersede the corresponding
term defined in the Base Indenture with respect to the Notes; 
 (c) the singular includes the plural and vice versa;

 (d) headings are for convenience of reference only and do not affect interpretation; and 

(e) the following terms have the meanings given to them in this Section 1.02(e): 

“2022 Notes Interest Payment Date” shall have the meaning set forth in Section 2.05(b). 

“2024 Notes Interest Payment Date” shall have the meaning set forth in Section 2.05(b). 

“2029 Notes Interest Payment Date” shall have the meaning set forth in Section 2.05(b). 

“2039 Notes Interest Payment Date” shall have the meaning set forth in Section 2.05(b). 

“2049 Notes Interest Payment Date” shall have the meaning set forth in Section 2.05(b). 

“2022 Notes Maturity Date” shall have the meaning set forth in Section 2.02(a). 

“2024 Notes Maturity Date” shall have the meaning set forth in Section 2.02(b). 

  
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 “2029 Notes Maturity Date” shall have the meaning set forth in
Section 2.02(c). 
 “2039 Notes Maturity Date” shall have the meaning set forth in Section 2.02(d). 

“2049 Notes Maturity Date” shall have the meaning set forth in Section 2.02(e). 

“Business Day” means any day other than a Saturday or Sunday, which is not a day on which banking institutions
in The City of New York are authorized or required by law, regulation or executive order to close. 
 “Change of
Control” means the occurrence of any of the following: (1) the consummation of any transaction (including, without limitation, any merger or consolidation) the result of which is that any “person” (as that term is defined in
Section 13(d)(3) of the Exchange Act) (other than (a) the Guarantor or one of its Subsidiaries, (b) any employee benefit plan of such Person or its Subsidiaries, and any Person acting in its capacity as trustee, agent or other
fiduciary or administrator of any such plan and (c) Steven M. Rales and Mitchell P. Rales) becomes the “beneficial owner” (as defined in Rules 13d-3 and
13d-5 under the Exchange Act), directly or indirectly, of more than 50% of the Guarantor’s Voting Stock or other Voting Stock into which the Guarantor’s Voting Stock is reclassified, consolidated,
exchanged or changed, measured by voting power rather than number of shares; (2) the direct or indirect sale, transfer, conveyance or other disposition (other than by way of merger or consolidation), in one or more series of related
transactions, of all or substantially all of the Guarantor’s assets and the assets of the Guarantor’s Subsidiaries, taken as a whole, to any “person” (as that term is defined in Section 13(d)(3) of the Exchange Act) (other
than the Guarantor or one of its Subsidiaries); or (3) the Guarantor ceases to own, directly or indirectly, 100% of the equity interests of the Company, other than as a result of the merger or consolidation of the Company with and into the
Guarantor. Notwithstanding the foregoing, a transaction will not be deemed to involve a Change of Control if (1) the Guarantor becomes a direct or indirect wholly-owned subsidiary of a holding company and (2)(A) the direct or indirect holders
of the Voting Stock of such holding company immediately following that transaction are substantially the same as the holders of the Guarantor’s Voting Stock immediately prior to that transaction or (B) immediately following that
transaction no Person (other than a holding company satisfying the requirements of this sentence) is the beneficial owner, directly or indirectly, of more than 50% of the Voting Stock of such holding company. 

“Change of Control Offer” shall have the meaning set forth in Section 3.03. 

“Change of Control Payment” shall have the meaning set forth in Section 3.03. 

“Change of Control Payment Date” shall have the meaning set forth in Section 3.03. 

“Change of Control Triggering Event,” with respect to any series of Notes, means the occurrence of both a
Change of Control and a Rating Event with respect to such series. No Change of Control Triggering Event will be deemed to have occurred in connection with any particular Change of Control unless and until such Change of Control has actually been
consummated. 

  
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 “Comparable Treasury Issue” means the United States
Treasury security selected by the Quotation Agent as having an actual interpolated maturity comparable to the remaining term of the Notes of a series to be redeemed (assuming that, with respect to the 2024 Notes, the 2029 Notes, the 2039 Notes and
the 2049 Notes, such notes to be redeemed matured on the applicable Par Call Date) that would be utilized, at the time of selection and in accordance with customary financial practice, in pricing new issues of corporate debt securities of comparable
maturity to the remaining term of the Notes of such series. 
 “Comparable Treasury Price” means, with
respect to any Redemption Date, (i) the average of four Reference Treasury Dealer Quotations for such Redemption Date, after excluding the highest and lowest such Reference Treasury Dealer Quotations, or (ii) if the Company obtains fewer
than four such Reference Treasury Dealer Quotations, the average of all such quotations, or (iii) if only one Reference Treasury Dealer Quotation is received, such Reference Treasury Dealer Quotation. 

“Depositary” means The Depository Trust Company or such successor selected or approved by the Company. 

“Envista” means Envista Holdings Corporation, a Delaware corporation. 

“Envista Entities” means Envista Holdings Corporation, a Delaware corporation, and each of its Subsidiaries.

 “Exchange Act” means the Securities Exchange Act of 1934, as amended. 

“GE Biopharma Acquisition” means the acquisition of the Biopharma Business of GE Life Sciences, by the
Guarantor pursuant to the Purchase Agreement. 
 “Global Note” shall have the meaning set forth in
Section 2.04. 
 “Interest Payment Date” means any 2022 Notes Interest Payment Date, 2024 Notes
Interest Payment Date, 2029 Notes Interest Payment Date, 2039 Notes Interest Payment Date or 2049 Notes Interest Payment Date, as applicable. 

“Investment Grade Rating” means a rating equal to or higher than Baa3 (or the equivalent) by Moody’s and BBB- (or the equivalent) by S&P; and, the equivalent investment grade credit rating from any additional rating agency or rating agencies selected by the Guarantor. 

“Issue Date” means November 7, 2019. 

“Maturity Date” means the 2022 Notes Maturity Date, the 2024 Notes Maturity Date, the 2029 Notes Maturity
Date, the 2039 Notes Maturity Date or the 2049 Notes Maturity Date, as applicable. 
 “Moody’s” means
Moody’s Investors Service Inc., and any successor to its rating agency business. 

  
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 “Par Call Date” means in the case of the 2024 Notes,
October 15, 2024; in the case of the 2029 Notes, August 15, 2029; in the case of the 2039 Notes, May 15, 2039; and in the case of the 2049 Notes, May 15, 2049. 

“Quotation Agent” means the Reference Treasury Dealer appointed by the Company. 

“Purchase Agreement” means the equity and asset purchase agreement, dated February 25, 2019, by and
between General Electric Company and the Guarantor as in effect on September 18, 2019. 
 “Rating
Agency” means (1) each of Moody’s and S&P; and (2) if either of Moody’s or S&P ceases to rate the applicable series of Notes or fails to make a rating of such series of Notes publicly available for reasons
outside of the Company’s or the Guarantor’s control, a “nationally recognized statistical rating organization” within the meaning of Section 3(a)(62) of the Exchange Act selected by the Guarantor (as certified by a Board
Resolution of the Guarantor) as a replacement agency for Moody’s or S&P, or both of them, as the case may be. 

“Rating Event” means the rating on the applicable series of Notes is lowered by each of the Rating Agencies
and such series of Notes is rated below an Investment Grade Rating by each of the Rating Agencies on any day within the 60-day period (which 60-day period will be
extended so long as the rating of such series of Notes is under publicly announced consideration for a possible downgrade by any of the Rating Agencies) after the earlier of (1) the occurrence of a Change of Control and (2) public notice
of the occurrence of a Change of Control or the Guarantor’s intention to effect a Change of Control; provided, however, that a Rating Event otherwise arising by virtue of a particular reduction in rating will not be deemed to have
occurred in respect of a particular Change of Control (and thus will not be deemed a Rating Event for purposes of the definition of Change of Control Triggering Event) if the Rating Agencies making the reduction in rating to which this definition
would otherwise apply do not announce or publicly confirm or inform the Trustee in writing at the Company’s or its request that the reduction was the result, in whole or in part, of any event or circumstance comprised of or arising as a result
of, or in respect of, the applicable Change of Control (whether or not the applicable Change of Control has occurred at the time of the Rating Event). 

“Record Date” means May 1 or November 1, whether or not a Business Day, immediately preceding the
related Interest Payment Date, which constitutes a Regular Record Date for purposes of the Base Indenture. 

“Redemption Date” means, with respect to any redemption of any series of Notes, the date fixed for such
redemption pursuant to the Indenture and such series of Notes. 
 “Reference Treasury Dealer” means
(i) BofA Securities, Inc. and Wells Fargo Securities, LLC (or their respective affiliates that are Primary Treasury Dealers) and their respective successors; provided, however, that if any of the foregoing shall cease to be a primary U.S.
Government securities dealer in the United States of America (a “Primary Treasury Dealer”), the Company will substitute therefor another Primary Treasury Dealer, and (ii) any other Primary Treasury Dealer selected by the
Company. 

  
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 “Reference Treasury Dealer Quotations” means, with respect
to each Reference Treasury Dealer and any Redemption Date, the average, as determined by the Company, of the bid and asked prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted in writing to
the Company by such Reference Treasury Dealer at 3:30 p.m., New York City time, on the third Business Day preceding such Redemption Date. 

“Remaining Scheduled Payments” means, with respect to each series of Notes to be redeemed, the remaining
scheduled payments of the principal thereof and interest thereon that would be due after the related Redemption Date (assuming that, with respect to the 2024 Notes, the 2029 Notes, the 2039 Notes and the 2049 Notes, such Notes to be redeemed matured
on the applicable Par Call Date) but for such redemption; provided, however, that, if such Redemption Date is not an Interest Payment Date with respect to the Notes of such series, the amount of the next succeeding scheduled interest payment thereon
will be deemed to be reduced by the amount of interest accrued thereon to such Redemption Date. 
 “S&P”
means S&P Global Ratings, a division of S&P Global Inc., and any successor to its rating agency business. 

“Separation Transaction” means any transaction in furtherance of the Guarantor’s previously disclosed
intentions to dispose of the common stock of Envista, including, without limitation, (i) an initial public offering or other offering(s) of shares of Envista, (ii) the distribution to the Guarantor of all or a portion of the proceeds of
such offering(s) and/or the proceeds of borrowings under the Envista Entities’ senior term credit facilities and (iii) the distribution by the Guarantor to its shareholders of all or a portion of the remaining equity interests in Envista
owned by the Guarantor, by means of a spin-off of Envista shares effected as a dividend to all the Guarantor’s shareholders, a split-off of Envista shares in
exchange for shares of the Guarantor or other securities, or any combination of the foregoing in one transaction or in a series of transactions. 

“Special Mandatory Redemption Date” means the earlier to occur of (1) September 24, 2020, if the GE
Biopharma Acquisition has not been completed on or prior to August 25, 2020 (or such later date to which the Purchase Agreement may be extended in accordance with its terms), or (2) the 30th day (or if such day is not a Business Day, the
first Business Day thereafter) following the termination of the Purchase Agreement. 
 “Special Mandatory Redemption
Price” shall have the meaning set forth in Section 3.04(a). 
 “Subsidiary” of any specified
Person means any corporation or other entity (including, without limitation, partnerships, joint ventures and associations) of which at least a majority of the outstanding stock having by the terms thereof ordinary voting power for the election of
directors of such corporation or other entity (irrespective of whether or not at the time stock of any other class or classes of such corporation shall have or might have voting power by reason of the happening of any contingency) is at the time
directly or indirectly owned by such Person, or by one or more Subsidiaries, or by such Person and one or more other Subsidiaries; provided, that, the Envista Entities shall be excluded from any such reference to a Subsidiary other than for
purposes of the “Envista Entities” definition. 

  
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 “Treasury Rate” means, with respect to any Redemption Date,
the rate per annum equal to the semi-annual equivalent yield to maturity (or interpolated yield to maturity on a day count basis) of the Comparable Treasury Issue, assuming a price for the Comparable Treasury Issue (expressed as a percentage of its
principal amount) equal to the Comparable Treasury Price of such Redemption Date. 
 “Voting Stock” means,
with respect to any specified Person as of any date, the capital stock of such Person that is at the time entitled to vote generally in the election of the Board of Directors or similar governing body of such Person. 

The terms “Base Indenture,” “Company,” “Guarantor,”
“Indenture,” “Notes” and “Trustee” shall have the respective meanings set forth in the recitals to this Supplemental Indenture and the paragraph preceding such recitals. 

ARTICLE II 
 GENERAL TERMS AND
CONDITIONS OF THE NOTES 
 Section 2.01 Designation and Principal Amount. Each series of Notes may be
issued from time to time upon written order of the Company for the authentication and delivery of such series of Notes pursuant to Section 303 of the Base Indenture. There are hereby authorized: 

(a) a series of Securities designated as the 2.050% Senior Notes due 2022, limited in initial aggregate principal amount
to $700,000,000 (except upon registration of transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 304, 305, 306, 906 or 1107 of the Base Indenture); 

(b) a series of Securities designated as the 2.200% Senior Notes due 2024, limited in initial aggregate principal amount
to $700,000,000 (except upon registration of transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 304, 305, 306, 906 or 1107 of the Base Indenture); 

(c) a series of Securities designated as the 2.600% Senior Notes due 2029, limited in initial aggregate principal amount
to $800,000,000 (except upon registration of transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 304, 305, 306, 906 or 1107 of the Base Indenture); 

(d) a series of Securities designated as the 3.250% Senior Notes due 2039, limited in initial aggregate principal amount
to $900,000,000 (except upon registration of transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 304, 305, 306, 906 or 1107 of the Base Indenture); and 

(e) a series of Securities designated as the 3.400% Senior Notes due 2049, limited in initial aggregate principal amount
to $900,000,000 (except upon registration of transfer of, or in exchange for, or in lieu of, other Securities pursuant to Section 304, 305, 306, 906 or 1107 of the Base Indenture). 

  
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 The Company may create and issue additional Notes of any series having the same terms and
conditions as such series of Notes in all respects (or in all respects except for the Issue Date, issue price and, to the extent applicable, the payment of interest accruing prior to the Issue Date of such additional Notes or the first payment of
interest following the Issue Date), so that such additional Notes of such series will be consolidated and form a single series with the initial Notes of such series. 

Section 2.02 Maturity. (a) The date upon which the 2022 Notes shall become due and payable
at final maturity, together with any accrued and unpaid interest, is November 15, 2022 (the “2022 Notes Maturity Date”), (b) the date upon which the 2024 Notes shall become due and payable at final maturity, together
with any accrued and unpaid interest, is November 15, 2024 (the “2024 Notes Maturity Date”), (c) the date upon which the 2029 Notes shall become due and payable at final maturity, together with any accrued and
unpaid interest, is November 15, 2029 (the “2029 Notes Maturity Date”), (d) the date upon which the 2039 Notes shall become due and payable at final maturity, together with any accrued and unpaid interest, is
November 15, 2039 (the “2039 Notes Maturity Date”) and (e) the date upon which the 2049 Notes shall become due and payable at final maturity, together with any accrued and unpaid interest, is
November 15, 2049 (the “2049 Notes Maturity Date”). 
 Section 2.03 Form, Payment
and Appointment. Except as provided in Section 2.04, each series of Notes shall be issued in fully registered, certificated form. Principal of and interest on each series of Notes will be payable, the transfer of such series of Notes will
be registrable, and such series of Notes will be exchangeable for such series of Notes of a like aggregate principal amount, at the office or agency of the Company maintained for such purpose located at 240 Greenwich Street, New York, New York
10286, which shall initially be the corporate trust office of the Trustee; provided, however, that payment of interest may be made at the option of the Company by check mailed to the Person entitled thereto at such address as shall
appear in the Security register or by wire transfer to an account appropriately designated by the Person entitled to payment; provided, that the Paying Agent shall have received written notice of such account designation at least five
(5) Business Days prior to the date of such payment (subject to surrender of the relevant Note in the case of a payment of interest on a Redemption Date or the Maturity Date). 

No service charge shall be made for any registration of transfer or exchange of any series of Notes, but the Company may
require payment from the applicable Holder of a sum sufficient to cover any tax or other governmental charge that may be imposed in connection therewith. 

The Security Registrar and Paying Agent for the Notes shall initially be the Trustee. 

The Notes of each series shall be issuable in denominations of U.S. $2,000 and integral multiples of U.S. $1,000 in excess
thereof. 
 The specified currency of the Notes shall be U.S. Dollars. 

Section 2.04 Global Notes. The Notes of each series shall be issued initially in the form of a permanent
Global Security in registered form (each, a “Global Note”), deposited with the Depositary. Unless and until such Global Note is exchanged for Notes of such series in certificated form, such Global Note may be transferred, in whole
but not in part, and any payments on the Notes of such series shall be made to the Paying Agent, which in turn shall make payment with respect to the applicable series of Notes to the Depositary or a nominee of the Depositary. 

  
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 Section 2.05 Interest on the Notes.
(a) Interest payable on any Interest Payment Date, Maturity Date or Redemption Date, shall be the amount of interest accrued from, and including, the immediately preceding Interest Payment Date in respect of which interest has
been paid or duly provided for (or from and including the Issue Date, if no interest has previously been paid or duly provided for) to, but excluding, such Interest Payment Date, Maturity Date or, if applicable, Redemption Date, as the case may be.
Interest on the Notes will be computed on the basis of a 360-day year consisting of twelve 30-day months. 

(b) The 2022 Notes will bear interest at the rate of 2.050% per year; the 2024 Notes will bear interest at the rate of
2.200% per year; the 2029 Notes will bear interest at the rate of 2.600% per year; the 2039 Notes will bear interest at the rate of 3.250% per year; and the 2049 Notes will bear interest at the rate of 3.400% per year. Interest on the 2022 Notes
shall be payable semi-annually in arrears on May 15 and November 15 of each year (each, a “2022 Notes Interest Payment Date”), commencing May 15, 2020; interest on the 2024 Notes shall be payable
semi-annually in arrears on May 15 and November 15 of each year (each, a “2024 Notes Interest Payment Date”), commencing May 15, 2020; interest on the 2029 Notes shall be payable semi-annually in arrears
on May 15 and November 15 of each year (each, a “2029 Notes Interest Payment Date”), commencing May 15, 2020; interest on the 2039 Notes shall be payable semi-annually in arrears on May 15 and
November 15 of each year (each, a “2039 Notes Interest Payment Date”), commencing May 15, 2020; and interest on the 2049 Notes shall be payable semi-annually in arrears on May 15 and November 15 of
each year (each, a “2049 Notes Interest Payment Date”), commencing May 15, 2020, in each case to the Persons in whose names such Notes are registered at the close of business on the Record Date for such Interest Payment
Date, except as provided in Section 2.06. 
 Section 2.06 In the event that any Interest Payment Date with
respect to any series of Notes or the Maturity Date or a Redemption Date for any series of Notes falls on a day that is not a Business Day, then the related payments of principal, premium, if any, and interest shall be made on the next succeeding
day that is a Business Day (and no additional interest will accrue or otherwise accumulate on the amount payable for the period from and after such Interest Payment Date, Maturity Date or Redemption Date, as applicable). Interest due on the Maturity
Date or a Redemption Date (in each case, whether or not an Interest Payment Date) of any series of Notes will be paid to the Person to whom principal of such Notes is payable. 

Section 2.07 Payments of Additional Amounts. The provisions of Section 1502 of the Base Indenture shall
apply to each series of Notes. Whenever in any series of Notes there is mentioned, in any context, the payment of the principal of or interest or any other amounts on, or in respect of, such series of Notes, such mention shall be deemed to include
mention of the payment of Additional Amounts to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof pursuant to the terms hereof and the Indenture, and express mention of the payment of Additional
Amounts in any provision of any series of Notes shall not be construed as excluding the payment of Additional Amounts in those provisions thereof where such express mention is not made. 

Section 2.08 No Sinking Fund. The Notes are not entitled to the benefit of any sinking fund. 

  
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 Section 2.09 Guarantees. Each series of Notes shall have
the benefit of a Guarantee from the Guarantor on the terms set forth in Article 14 of the Base Indenture. 
 ARTICLE III 

REDEMPTION OF THE NOTES 

Section 3.01 Optional Redemption by Company. (a) At any time and from time to time prior
to (i) the applicable Par Call Date for the 2024 Notes, the 2029 Notes, the 2039 Notes and the 2049 Notes and (ii) the 2022 Notes Maturity Date for the 2022 Notes, the Company has the right, at its option, to redeem any series of Notes, in
whole or in part, at a redemption price equal to the greater of: 
 (i) 100% of the principal amount of the Notes to
be redeemed, and 
 (ii) the sum of the present values of the Remaining Scheduled Payments on such Notes to be
redeemed (not including any portion of the payments of interest that will be accrued and unpaid to and including the Redemption Date) discounted to the Redemption Date on a semi-annual basis (assuming a
360-day year consisting of twelve 30-day months) at the applicable Treasury Rate plus 10 basis points, in the case of the 2022 Notes, 10 basis points, in the case of the
2024 Notes, 15 basis points, in the case of the 2029 Notes, 15 basis points, in the case of the 2039 Notes and 20 basis points, in the case of the 2049 Notes, 

plus, in each case, accrued and unpaid interest, if any, on the principal amount of the Notes being redeemed to, but excluding, the Redemption
Date. 
 (b) On or after the applicable Par Call Date, the Company has the right, at its option, to redeem the 2024
Notes, the 2029 Notes, the 2039 Notes and the 2049 Notes, in whole or in part, at any time and from time to time, at a redemption price equal to 100% of the principal amount of such Notes to be redeemed, plus accrued and unpaid interest, if any, on
the principal amount of such Notes being redeemed to, but excluding, the Redemption Date. 
 (c) The Company will
cause the notice of any redemption to be mailed (or sent electronically in accordance with applicable Depositary procedures) to the registered Holders of the applicable Notes to be redeemed not less than 15 nor more than 60 days prior to the
Redemption Date. Any notice may, at the discretion of the Company be subject to the satisfaction or waiver of one or more conditions precedent. In that case, the notice shall state the nature of such condition precedent. If a series of Notes is only
partially redeemed pursuant to this Section 3.01, such Notes to be redeemed will be selected by the Trustee in such manner as in its sole discretion it shall deem appropriate and fair, subject to any applicable Depositary procedures. The price
for any redemption pursuant to this Section 3.01 shall be paid prior to 12:00 noon, New York City time, on the applicable Redemption Date or at such later time as is then permitted by the rules of the Depositary applicable to such series of
Notes (if then registered as Global Notes); provided, that the Company shall deposit with the Trustee or the Paying Agent an amount sufficient to pay the applicable redemption price by 10:00 a.m., New York City time, on the date such
redemption price is to be paid. 

  
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 (d) If money sufficient to pay the redemption price of all of the
Notes (or a portion thereof) to be redeemed on the applicable Redemption Date is deposited with the Trustee or the Paying Agent on or before such Redemption Date as provided herein, then on and after such Redemption Date, interest will cease to
accrue on such series of Notes (or such portion thereof) called for redemption. 
 Section 3.02 Redemption Upon
Changes in Withholding Tax. The provisions of Section 1501 of the Base Indenture shall apply to each series of Notes. The redemption price for any redemption pursuant to this Section 3.02 shall be paid prior to 12:00 noon, New York
City time, on the applicable Redemption Date or at such later time as is then permitted by the rules of the Depositary applicable to the Notes (if then registered as Global Notes); provided, that the Company shall deposit with the Trustee or the
Paying Agent an amount sufficient to pay such redemption price by 10:00 a.m., New York City time, on the date such redemption price is to be paid. If money sufficient to pay such redemption price of each series of Notes to be redeemed on the
applicable Redemption Date is deposited with the Trustee or the Paying Agent on or before such Redemption Date as provided herein, then on and after such Redemption Date, interest will cease to accrue on such Notes called for redemption. 

Section 3.03 Change of Control Triggering Event. (a) If a Change of Control Triggering
Event occurs, unless the Company has exercised its right to redeem the Notes in full as described in Section 3.01, or with respect to any series of Notes, such series of Notes has become redeemable as described in Section 3.02 or 3.04,
Holders of each series of Notes will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of their Notes pursuant to the offer described below (the “Change
of Control Offer”) on the terms set forth in the Notes. In the Change of Control Offer, the Company will be required to offer payment in cash equal to 101% of the aggregate principal amount of Notes repurchased plus accrued and unpaid
interest, if any, on the Notes repurchased to the date of purchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, or, at the Company’s option, prior to the date of the
consummation of any Change of Control, but after public announcement of the transaction that constitutes or may constitute the Change of Control, the Company will be required to mail a notice to Holders of each applicable series of Notes, with a
copy to the Trustee, describing the transaction or transactions that constitute or may constitute the Change of Control Triggering Event and offering to repurchase such applicable series of Notes on the date specified in the notice, which date will
be no earlier than 30 days and no later than 60 days from the date such notice is mailed (the “Change of Control Payment Date”), pursuant to the procedures required by the Notes and described in such notice. The notice shall, if
mailed prior to the date of the consummation of the Change of Control, state that the offer to purchase is conditioned on the Change of Control Triggering Event occurring on or prior to the Change of Control Payment Date. The Company must comply
with the requirements of Rule 14e-1 under the Exchange Act and any other securities laws and regulations thereunder to the extent those laws and regulations are applicable in connection with the repurchase of
the Notes as a result of a Change of Control Triggering Event. To the extent that the provisions of any securities laws or regulations conflict with the Change of Control Triggering Event provisions of the Notes, the Company will comply with the
applicable securities laws and regulations and will not be deemed to have breached its obligations under this Section 3.03 or the Change of Control Triggering Event provisions of the Notes by virtue of such conflicts. 

  
 - 12 - 













 (b) On the Change of Control Payment Date, the Company will be
required, to the extent lawful, to: 
 (i) accept for payment all Notes of each applicable series, or portions of such
Notes, properly tendered pursuant to the Change of Control Offer; 
 (ii) deposit with the Paying Agent an amount
equal to the Change of Control Payment in respect of all Notes of each applicable series, or portions of such Notes, properly tendered; and 

(iii) deliver or cause to be delivered to the Trustee the Notes of each applicable series properly accepted together
with an Officers’ Certificate stating the aggregate principal amount of such Notes, or portions of such Notes, being repurchased. 

(c) The Paying Agent will promptly mail to each Holder of Notes of each applicable series properly tendered the Change
of Control Payment for such Notes, and the Trustee will promptly authenticate and mail (or cause to be transferred by book-entry) to each such Holder a new Note of such series equal in principal amount to any unpurchased portion of any Notes of such
series surrendered; provided that each new Note will be in a principal amount of $2,000 or an integral multiple of $1,000 in excess thereof. The Company will not be required to make an offer to repurchase Notes of any series upon a Change of
Control Triggering Event if a third party makes such an offer in the manner, at the times and otherwise in compliance with the requirements for an offer made by the Company and such third party purchases all Notes of each such series properly
tendered and not withdrawn under its offer. In addition, the Company will not repurchase any Notes if there has occurred and is continuing on the Change of Control Payment Date an Event of Default under the Indenture, other than a default in the
payment of the Change of Control Payment upon a Change of Control Triggering Event. 
 Section 3.04 Special
Mandatory Redemption. (a) In the event that the Guarantor does not consummate the GE Biopharma Acquisition on or prior to August 25, 2020 (or such later date to which the Purchase Agreement may be extended in accordance
with its terms), or the Purchase Agreement is terminated at any time prior to August 25, 2020, then the Company must redeem, in whole and not in part, each series of Notes on the Special Mandatory Redemption Date at a redemption price (the
“Special Mandatory Redemption Price”) equal to 101% of the aggregate principal amount of each such series of Notes outstanding, plus accrued and unpaid interest from the most recent Interest Payment Date to which interest has
been paid or duly provided for or, if no interest has been paid, from the Issue Date to, but excluding, the Special Mandatory Redemption Date. 

(b) The Company will cause the notice of such Special Mandatory Redemption to be mailed, with a copy to the Trustee,
within five Business Days after the occurrence of the event triggering such Special Mandatory Redemption to each Holder of Notes at its registered address. The Special Mandatory Redemption Price shall be paid prior to 12:00 noon, New York City time,
on the Special Mandatory Redemption Date or at such later time as is then permitted by the rules of the Depositary applicable to the Notes (if then registered as Global Notes); provided, that the Company shall deposit with the Trustee or the Paying
Agent an amount sufficient to pay the Special Mandatory Redemption Price by 10:00 a.m., New York City time, on the date such Special Mandatory Redemption Price is to be paid. 

  
 - 13 - 













 (c) If money sufficient to pay the Special Mandatory Redemption Price
of each series of Notes to be redeemed on the Special Mandatory Redemption Date is deposited with the Trustee or Paying Agent on or before the Special Mandatory Redemption Date as provided herein, then on and after such Special Mandatory Redemption
Date, interest will cease to accrue on such Notes. 
 ARTICLE IV 

FORM OF NOTES AND GUARANTEES 

Section 4.01 Form of Notes and Guarantees. The Notes and the Trustee’s Certificates of Authentication to
be endorsed thereon are to be substantially in the forms attached as Exhibits A through E hereto, in each case with such changes therein as the officers of the Company executing the Notes (by manual or facsimile signature) may approve,
such approval to be conclusively evidenced by his or her execution thereof. The notation of Guarantee to be attached to each Note is to be substantially in the form attached as Exhibit F hereto, with such changes therein as the officer of the
Guarantor executing the notation of Guarantee (by manual or facsimile signature) may approve, such approval to be conclusively evidenced by their execution thereof. 

ARTICLE V 
 ORIGINAL ISSUE OF NOTES

 Section 5.01 Original Issue of Notes. 2022 Notes having an initial aggregate principal amount of
$700,000,000, 2024 Notes having an initial aggregate principal amount of $700,000,000, 2029 Notes having an initial aggregate principal amount of $800,000,000, 2039 Notes having an initial aggregate principal amount of $900,000,000 and 2049 Notes
having an initial aggregate principal amount of $900,000,000 may from time to time, upon execution of this Supplemental Indenture, be executed by the Company and delivered to the Trustee for authentication, and the Trustee shall thereupon
authenticate and deliver said Notes to or upon the written order of the Company pursuant to Section 303 of the Base Indenture without any further action by the Company (other than as required by the Base Indenture).  

ARTICLE VI 
 COVENANTS 

Section 6.01 Additional Exception to Limitation on Secured Debt. Section 1010 of the Indenture shall not
apply to debt secured by any security interests on any property, assets or equity or other ownership interests created to secure Indebtedness incurred by the Guarantor or any of its Subsidiaries in connection with a Separation Transaction; provided
that this clause shall cease to apply to any such security interests to the extent (1) the applicable Separation Transaction has not been consummated within 180 days of the creation of such security interests or (2) such security interests
continue to encumber property, assets or equity or other ownership interests of the Guarantor or any of its Subsidiaries as of a date which is 30 days after the consummation of such Separation Transaction. 

  
 - 14 - 













 ARTICLE VII 

MISCELLANEOUS 

Section 7.01 Ratification and Applicability of Indenture. To the extent of any conflict between the
provisions of this Supplemental Indenture and the Base Indenture, the provisions of this Supplemental Indenture shall control. The provisions of Sections 1302 and 1303 of the Base Indenture shall apply to the Notes (including with respect to
Section 6.01 of this Supplemental Indenture). Except as otherwise provided in Section 1.02 and this Section 7.01, the Base Indenture is in all respects ratified and confirmed, and this Supplemental Indenture shall be deemed part of
the Base Indenture in the manner and to the extent herein and therein provided. 
 Section 7.02 Trustee Not
Responsible for Recitals. The recitals herein contained are made by the Company and the Guarantor and not by the Trustee, and the Trustee assumes no responsibility for the correctness thereof. The Trustee makes no representation as to the
validity or sufficiency of this Supplemental Indenture. 
 Section 7.03 New York Law to Govern. THIS
SUPPLEMENTAL INDENTURE AND EACH NOTE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE CONSTRUED IN ACCORDANCE WITH THE LAWS OF SAID STATE. FOR THE AVOIDANCE OF DOUBT, THE APPLICABILITY OF
ARTICLES 470-3 to 470-19 OF THE LUXEMBOURG LAW DATED AUGUST 10, 1915 ON COMMERCIAL COMPANIES, AS AMENDED, SHALL BE EXCLUDED. 

Section 7.04 Separability. In case any one or more of the provisions contained in this Supplemental Indenture
or in any series of the Notes shall for any reason be held to be invalid, illegal or unenforceable in any respect, then, to the extent permitted by law, such invalidity, illegality or unenforceability shall not affect any other provisions of this
Supplemental Indenture or of such series of the Notes, but this Supplemental Indenture and such series of the Notes shall be construed as if such invalid or illegal or unenforceable provision had never been contained herein or therein. 

Section 7.05 Counterparts. This Supplemental Indenture may be executed in any number of counterparts each of
which shall be an original, but such counterparts shall together constitute but one and the same instrument. 

  
 - 15 - 













 IN WITNESS WHEREOF the parties hereto have caused this Supplemental Indenture to be duly
executed, as of the day and year first written above. 
  

			
	DH EUROPE FINANCE II S.À R.L.


 
			
		
	By:	 	 


 
			
	Name:	 	 


 
			
	Title:	 	 


  

			
	DANAHER CORPORATION


 
			
		
	By:	 	 


 
			
	Name:	 	 


 
			
	Title:	 	 


  

			
	THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., as Trustee


 
			
		
	By:	 	 


 
			
	Name:	 	 


 
			
	Title:	 	 


 [Signature Page to Second Supplemental Indenture] 












 EXHIBIT A 

[IF THIS NOTE IS TO BE A GLOBAL SECURITY, INSERT:] 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO
THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF,
CEDE & CO., HAS AN INTEREST HEREIN. 
 THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED
TO AND IS REGISTERED IN THE NAME OF DTC OR A NOMINEE THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN DTC OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND MAY NOT BE
TRANSFERRED EXCEPT AS A WHOLE BY DTC TO A NOMINEE OF DTC OR BY A NOMINEE OF DTC TO DTC OR ANOTHER NOMINEE OF DTC. 
 DH EUROPE FINANCE II
S.À R.L. 
 2.050% Senior Note due 2022 
  

					
	          No.
                                    	  		  	$
                                        


 CUSIP: 23291K AF2 

ISIN: US23291KAF21 

DH Europe Finance II S.à r.l., a private limited liability company (société à
responsabilité limitée) duly organized and existing under the laws of Luxembourg, having its registered office at 1 B Heienhaff, L-1736 Senningerberg, Grand Duchy of Luxembourg and registered
with the Luxembourg Trade and Companies Register under number B 235.237 (herein called the “Company,” which term includes any successor Person under the Indenture hereinafter referred to), for value received, hereby promises to pay
to ________________, or registered assigns, the principal sum set forth in the Schedule of Increases or Decreases in Note attached hereto on November 15, 2022, and to pay interest thereon from November 7, 2019 or from the immediately
preceding Interest Payment Date to which interest has been paid or duly provided for, semi-annually in arrears on May 15 and November 15 of each year, commencing May 15, 2020 at the rate of 2.050% per annum, until the principal hereof
is paid or made available for payment. Interest shall be computed on the basis of a 360-day year consisting of twelve 30-day months. The interest so payable, and
punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered on the Security Register at the close of business
on the Regular Record Date for such interest, which shall be May 1 or November 1, whether or not a Business Day, immediately preceding the related Interest Payment Date, except as provided in Section 2.06 of the Supplemental
Indenture. 

  
 A-1 













 Any such interest not so punctually paid or duly provided for will forthwith
cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the payment of such
Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of this Note not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of
any securities exchange on which the Notes of this series may be listed, and upon such notice as may be required by such exchange, all as more fully provided in said Indenture. 

Payment of the principal of (and premium, if any) and interest on this Note will be made at the office or agency of the Company
maintained for that purpose in accordance with the Indenture, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided, however, that at the option of
the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register or by wire transfer to an account maintained by the Person entitled thereto as specified
in the Security Register. 
 This Note is fully and unconditionally guaranteed by Danaher Corporation, a corporation duly
organized and existing under the laws of the State of Delaware (the “Guarantor”), as provided in the Indenture. 

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall
for all purposes have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has
been executed by the Trustee referred to on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its corporate seal. 

Dated:
                             

 

			
	DH EUROPE FINANCE II S.À R.L.


 
			
		
	By: 	 	 


 
			
	Name:	 	 


 
			
	Title: 	 	 



  
 A-2 













 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Notes of the series designated therein described in the within-mentioned Indenture. 

Dated:
                                        
 
 THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., 

as Trustee 

By:                      
                               

Authorized Signatory 

  
 A-3 













 REVERSE OF NOTE 

This Note is one of a duly authorized issue of Securities of the Company (herein called the “Notes”), issued
and to be issued in one or more series under a Base Indenture, dated as of September 18, 2019 (as heretofore supplemented, herein called the “Base Indenture”), among the Company, the Guarantor and The Bank of New York Mellon
Trust Company, N.A., as Trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture), as supplemented by the Second Supplemental Indenture, dated as of November 7, 2019 (herein called the
“Supplemental Indenture,” which term shall have the meaning assigned to it in such instrument, and together with the Base Indenture, herein called the “Indenture”) and reference is hereby made to the Indenture for a
statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Guarantor, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be authenticated and delivered.
This Note is one of the series designated on the face hereof initially limited in aggregate principal amount to $700,000,000. The Notes are unsecured general obligations of the Company. 

 

	 	1.	 Optional Redemption 



At any time and from time to time prior to November 15, 2022, the Company shall have the right to redeem the Notes, in
whole or in part, at its option, at a redemption price equal to the greater of: 
 (i) 100% of the principal amount of
the Notes to be redeemed; and 
 (ii) the sum of the present values of the Remaining Scheduled Payments on the Notes
to be redeemed (not including any portion of the payments of interest that will be accrued and unpaid to and including the Redemption Date) discounted to the Redemption Date on a semi-annual basis (assuming a
360-day year consisting of twelve 30-day months) at the applicable Treasury Rate plus 10 basis points, plus accrued and unpaid interest, if any, on the principal amount
of the Notes being redeemed to, but excluding, the Redemption Date. 
 The Company will mail (or send electronically in
accordance with applicable Depositary procedures) notice of any redemption to the registered Holders of the Notes to be redeemed not less than 15 nor more than 60 days prior to the Redemption Date. Any notice may, at the discretion of the Company be
subject to the satisfaction or waiver of one or more conditions precedent. In that case, the notice shall state the nature of such condition precedent. If the Notes are only partially redeemed pursuant to Section 3.01 of the Supplemental
Indenture, the Notes to be redeemed will be selected by the Trustee in such manner as in its sole discretion it shall deem appropriate and fair, subject to any applicable Depositary procedures. 

If money sufficient to pay the redemption price of all of the Notes (or a portion thereof) to be redeemed on the Redemption
Date is deposited with the Trustee or Paying Agent on or before the Redemption Date as provided herein and in the Indenture, then on and after such Redemption Date, interest will cease to accrue on such Notes (or such portion thereof) called for
redemption. 

  
 A-4 













 In the event of redemption of this Note in part only, a new Note or Notes
for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 
  

	 	2.	 Special Mandatory Redemption 



In the event that the Guarantor does not consummate the GE Biopharma Acquisition on or prior to August 25, 2020 (or such
later date to which the Purchase Agreement may be extended in accordance with its terms) or the Purchase Agreement is terminated at any time prior thereto (or such later date to which the Purchase Agreement may be extended in accordance with
its terms), then the Company must redeem, in whole and not in part, all of the Notes on the Special Mandatory Redemption Date at a redemption price (the “Special Mandatory Redemption Price”) equal to 101% of the aggregate principal
amount of the Notes outstanding, plus accrued and unpaid interest from the most recent Interest Payment Date to which interest has been paid or duly provided for or, if no interest has been paid, from the Issue Date to, but excluding, the Special
Mandatory Redemption Date. 
 The Company will mail notice of such Special Mandatory Redemption, with a copy to the Trustee,
within five Business Days after the occurrence of the event triggering such Special Mandatory Redemption to each Holder of Notes at its registered address. 

If money sufficient to pay the Special Mandatory Redemption Price of all of the Notes to be redeemed on the Special Mandatory
Redemption Date is deposited with the Trustee or Paying Agent on or before the Special Mandatory Redemption Date as provided herein and in the Indenture, then on and after such Special Mandatory Redemption Date, interest will cease to accrue on such
Notes. 
  

	 	3.	 Redemption Upon Changes in Withholding Taxes; Additional Amounts 



The provisions of Sections 1501 and 1502 of the Base Indenture and Sections 2.07 and 3.02 of the Supplemental Indenture shall
apply to this series of Notes. 
 Whenever the payment of the principal of or interest or any other amounts on, or in respect
of, this Note is mentioned, in any context, such mention shall be deemed to include mention of the payment of Additional Amounts to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof pursuant to the
terms of the Indenture, and express mention of the payment of Additional Amounts in any provision of this series of Notes shall not be construed as excluding the payment of Additional Amounts in those provisions thereof where such express mention is
not made. 
  

	 	4.	 No Other Redemption 



Except as set forth in Sections 1, 2 and 3 of this Note and in Article 3 of the Supplemental Indenture, the Company may not
redeem the Notes prior to the Maturity Date. 

  
 A-5 














	 	5.	 Change of Control Triggering Event 



If a Change of Control Triggering Event occurs, unless the Notes of this series have become redeemable as described in Sections
3.01 and 3.02 of the Supplemental Indenture, Holders of the Notes of this series will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of their Notes pursuant
to the offer described below (the “Change of Control Offer”) on the terms set forth herein. In the Change of Control Offer, the Company will be required to offer payment in cash equal to 101% of the aggregate principal amount of
Notes repurchased plus accrued and unpaid interest, if any, on the Notes repurchased to the date of purchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, or, at the
Company’s option, prior to the date of the consummation of any Change of Control, but after public announcement of the transaction that constitutes or may constitute the Change of Control, the Company will be required to mail a notice to
Holders of the Notes, with a copy to the Trustee, describing the transaction or transactions that constitute or may constitute the Change of Control Triggering Event and offering to repurchase the Notes on the date specified in the notice, which
date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed (the “Change of Control Payment Date”), pursuant to the procedures required by the Indenture and described in such notice. The notice
shall, if mailed prior to the date of the consummation of the Change of Control, state that the offer to purchase is conditioned on the Change of Control Triggering Event occurring on or prior to the Change of Control Payment Date. 

On the Change of Control Payment Date, the Company will be required, to the extent lawful, to: 

(i) accept for payment all of the Notes, or portions of the Notes, properly tendered pursuant to the Change of Control
Offer; 
 (ii) deposit with the Paying Agent an amount equal to the Change of Control Payment in respect of all of the
Notes, or portions of the Notes, properly tendered; and 
 (iii) deliver or cause to be delivered to the Trustee the
Notes properly accepted together with an Officers’ Certificate stating the aggregate principal amount of Notes, or portions of Notes, being repurchased. 

The Paying Agent will promptly mail to each Holder of Notes properly tendered the Change of Control Payment for such Notes, and
the Trustee will promptly authenticate and mail (or cause to be transferred by book-entry) to each such Holder a new Note equal in principal amount to any unpurchased portion of any Notes surrendered; provided that each new Note will be in a
principal amount of $2,000 or an integral multiple of $1,000 in excess thereof. The Company will not be required to make an offer to repurchase the Notes upon a Change of Control Triggering Event if a third party makes such an offer in the manner,
at the times and otherwise in compliance with the requirements for an offer made by the Company and such third party purchases all Notes properly tendered and not withdrawn under its offer. 

In addition, the Company will not repurchase any Notes if there has occurred and is continuing on the Change of Control Payment
Date an Event of Default under the Indenture, other than a default in the payment of the Change of Control Payment upon a Change of Control Triggering Event. 

  
 A-6 














	 	6.	 No Sinking Fund 



The Notes are not entitled to the benefit of any sinking fund. 

 

	 	7.	 Defeasance and Discharge 



The Indenture contains provisions for defeasance and discharge and for defeasance at any time of certain restrictive covenants
and Events of Default with respect to this Note upon compliance with certain conditions set forth in the Indenture. 
  

	 	8.	 Guarantee 



This Note is fully and unconditionally guaranteed by the Guarantor, as provided in Article 14 of the Indenture. 

 

	 	9.	 Modification and Waiver 



The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights
and obligations of the Company and the Guarantor and the rights of the Holders of the Notes of each series to be affected under the Indenture at any time by the Company, the Guarantor and the Trustee with the consent of the Holders of a majority in
principal amount of the Notes at the time Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the Notes of each series at the time Outstanding, on
behalf of the Holders of all Notes of such series, to waive compliance by the Company and the Guarantor with certain provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the
Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such
consent or waiver is made upon this Note. Without notice to or consent of any Holder, the parties thereto may amend or supplement the Indenture and the Notes to, among other things, cure any ambiguity, defect or inconsistency, provide for
uncertificated Notes in addition to or in place of certificated Notes, or make any other change that does not adversely affect the rights of any Holder of a Note. 
  

	 	10.	 Events of Default 



If an Event of Default with respect to the Notes shall occur and be continuing, the principal of the Notes may be declared due
and payable in the manner and with the effect provided in the Indenture. 

  
 A-7 














	 	11.	 Remedies 



As provided in and subject to the provisions of the Indenture, the Holder of this Note shall not have the right to institute
any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect
to the Notes of this series, the Holders of not less than 25% in principal amount of the Notes of this series at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as
Trustee and offered the Trustee reasonable indemnity, and the Trustee shall not have received from the Holders of a majority in principal amount of Notes of this series at the time Outstanding a direction inconsistent with such request, and shall
have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this Note for the enforcement of any payment of principal
hereof or any premium or interest hereon on or after the respective due dates expressed herein. 
 No reference herein to the
Indenture and no provision of this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and any premium and interest on this Note at the times, place and rate, and
in the coin or currency, herein prescribed. 
  

	 	12.	 Transfer and Exchange 



As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Note is registrable in
the Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any place where the principal of and any premium and interest on this Note are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Notes of this series are issuable only in registered form without coupons in denominations of $2,000 or an integral
multiple of $1,000 thereof. As provided in the Indenture and subject to certain limitations therein set forth, Notes of this series are exchangeable for a like aggregate principal amount of Notes of this series and of like tenor of a different
authorized denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Company, the Guarantor, the Trustee and any agent of
the Company, the Guarantor or the Trustee may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and none of the Company, the Guarantor, the Trustee nor any such agent
shall be affected by notice to the contrary. 

  
 A-8 














	 	13.	 Governing Law 



THIS NOTE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE
CONSTRUED IN ACCORDANCE WITH THE LAWS OF SAID STATE. FOR THE AVOIDANCE OF DOUBT, THE APPLICABILITY OF ARTICLES 470-3 to 470-19 OF THE LUXEMBOURG LAW DATED
AUGUST 10, 1915 ON COMMERCIAL COMPANIES, AS AMENDED, SHALL BE EXCLUDED. 
  

	 	14.	 Defined Terms 



All terms used in this Note which are defined in the Indenture shall have the meanings assigned to them in the Indenture. As
used in this Note, the term “Predecessor Note” shall have the meaning assigned to the term “Predecessor Security” in the Indenture. 

  
 A-9 













 ASSIGNMENT 
  

			
		 	FOR VALUE RECEIVED, the undersigned assigns and transfers this Note to:
		
		 	  

		
		 	  

		
		 	(Insert assignee’s social security or tax identification number)
		
		 	  

		
		 	  

		
		 	  

		
		 	(Insert address and zip code of assignee) and irrevocably appoints
		
		 	  

		
		 	  

		
		 	  

		
		 	agent to transfer this Note on the books of the Company. The agent may substitute another to act for him or her.
		
		 	 Date:
                            



			
		
		  	 Signature:
                                         
           

		
		  	 Signature Guarantee:
                                   


 (Sign exactly as your name appears on the other side of this Note) 

  
 A-10 













 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security
Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in
addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 

  
 A-11 













 SCHEDULE OF INCREASES OR DECREASES IN NOTE 

The initial principal amount of this Note is $            . The following
increases or decreases in the principal amount of this Note have been made: 
  

									
	 Date
	 	 Amount of

decrease in

principal
 amount of
this
 Note
	 	 Amount of

increase in

principal
 amount of
this
 Note
	  	 Principal

amount of this
 Note
following
 such decrease

or increase
	  	 Signature of

authorized
 signatory
of
 Trustee

		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
	  
	 	  
	 	  
	  	  
	  	  



  
 A-12 













 EXHIBIT B 

[IF THIS NOTE IS TO BE A GLOBAL SECURITY, INSERT:] 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO
THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF,
CEDE & CO., HAS AN INTEREST HEREIN. 
 THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED
TO AND IS REGISTERED IN THE NAME OF DTC OR A NOMINEE THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN DTC OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND MAY NOT BE
TRANSFERRED EXCEPT AS A WHOLE BY DTC TO A NOMINEE OF DTC OR BY A NOMINEE OF DTC TO DTC OR ANOTHER NOMINEE OF DTC. 
 DH EUROPE FINANCE II
S.À R.L. 
 2.200% Senior Note due 2024 
  

					
	No.                                     	  		  	$                             
			
		  		  	CUSIP: 23291K AG0
		  		  	ISIN: US23291KAG04

 DH Europe Finance II S.à r.l., a private limited liability company
(société à responsabilité limitée) duly organized and existing under the laws of Luxembourg, having its registered office at 1 B Heienhaff, L-1736 Senningerberg, Grand
Duchy of Luxembourg and registered with the Luxembourg Trade and Companies Register under number B 235.237 (herein called the “Company,” which term includes any successor Person under the Indenture hereinafter referred to), for
value received, hereby promises to pay to ________________, or registered assigns, the principal sum set forth in the Schedule of Increases or Decreases in Note attached hereto on November 15, 2024, and to pay interest thereon from
November 7, 2019 or from the immediately preceding Interest Payment Date to which interest has been paid or duly provided for, semi-annually in arrears on May 15 and November 15 of each year, commencing May 15, 2020 at the rate
of 2.200% per annum, until the principal hereof is paid or made available for payment. Interest shall be computed on the basis of a 360-day year consisting of twelve
30-day months. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Person in whose name this Note (or one or more
Predecessor Notes) is registered on the Security Register at the close of business on the Regular Record Date for such interest, which shall be May 1 or November 1, whether or not a Business Day, immediately preceding the related Interest
Payment Date, except as provided in Section 2.06 of the Supplemental Indenture. 

  
 B-1 













 Any such interest not so punctually paid or duly provided for will forthwith
cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the payment of such
Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of this Note not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of
any securities exchange on which the Notes of this series may be listed, and upon such notice as may be required by such exchange, all as more fully provided in said Indenture. 

Payment of the principal of (and premium, if any) and interest on this Note will be made at the office or agency of the Company
maintained for that purpose in accordance with the Indenture, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided, however, that at the option of
the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register or by wire transfer to an account maintained by the Person entitled thereto as specified
in the Security Register. 
 This Note is fully and unconditionally guaranteed by Danaher Corporation, a corporation duly
organized and existing under the laws of the State of Delaware (the “Guarantor”), as provided in the Indenture. 

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall
for all purposes have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has
been executed by the Trustee referred to on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its corporate seal. 

Dated:
                         
  

			
	DH EUROPE FINANCE II S.À R.L.
		
	By:	 	              

	Name:	 	              

	Title:	 	  




  
 B-2 













 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Notes of the series designated therein described in the within-mentioned Indenture. 

Dated:
                         

THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., 

as Trustee 
 By:
                                        

 Authorized Signatory 

  
 B-3 













 REVERSE OF NOTE 

This Note is one of a duly authorized issue of Securities of the Company (herein called the “Notes”), issued
and to be issued in one or more series under a Base Indenture, dated as of September 18, 2019 (as heretofore supplemented, herein called the “Base Indenture”), among the Company, the Guarantor and The Bank of New York Mellon
Trust Company, N.A., as Trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture), as supplemented by the Second Supplemental Indenture, dated as of November 7, 2019 (herein called the
“Supplemental Indenture,” which term shall have the meaning assigned to it in such instrument, and together with the Base Indenture, herein called the “Indenture”) and reference is hereby made to the Indenture for a
statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Guarantor, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be authenticated and delivered.
This Note is one of the series designated on the face hereof initially limited in aggregate principal amount to $700,000,000. The Notes are unsecured general obligations of the Company. 

 

	 	1.	 Optional Redemption 



At any time and from time to time prior to October 15, 2024, the Company shall have the right to redeem the Notes, in
whole or in part, at its option, at a redemption price equal to the greater of: 
 (i)    100% of
the principal amount of the Notes to be redeemed; and 
 (ii)    the sum of the present values of
the Remaining Scheduled Payments on the Notes to be redeemed (not including any portion of the payments of interest that will be accrued and unpaid to and including the Redemption Date) discounted to the Redemption Date on a semi-annual basis
(assuming a 360-day year consisting of twelve 30-day months) at the applicable Treasury Rate plus 10 basis points, plus accrued and unpaid interest, if any, on the
principal amount of the Notes being redeemed to, but excluding, the Redemption Date. 
 On or after October 15, 2024,
the Company shall have the right, at its option, to redeem the Notes, in whole or in part, at any time and from time to time, at a redemption price equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest,
if any, on the principal amount of the Notes being redeemed to, but excluding, the Redemption Date. 
 The Company will mail
(or send electronically in accordance with applicable Depositary procedures) notice of any redemption to the registered Holders of the Notes to be redeemed not less than 15 nor more than 60 days prior to the Redemption Date. Any notice may, at the
discretion of the Company be subject to the satisfaction or waiver of one or more conditions precedent. In that case, the notice shall state the nature of such condition precedent. If the Notes are only partially redeemed pursuant to
Section 3.01 of the Supplemental Indenture, the Notes to be redeemed will be selected by the Trustee in such manner as in its sole discretion it shall deem appropriate and fair, subject to any applicable Depositary procedures. 

  
 B-4 













 If money sufficient to pay the redemption price of all of the Notes (or a
portion thereof) to be redeemed on the Redemption Date is deposited with the Trustee or Paying Agent on or before the Redemption Date as provided herein and in the Indenture, then on and after such Redemption Date, interest will cease to accrue on
such Notes (or such portion thereof) called for redemption. 
 In the event of redemption of this Note in part only, a new
Note or Notes for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 
  

	 	2.	 Special Mandatory Redemption 



In the event that the Guarantor does not consummate the GE Biopharma Acquisition on or prior to August 25, 2020 (or such
later date to which the Purchase Agreement may be extended in accordance with its terms) or the Purchase Agreement is terminated at any time prior thereto (or such later date to which the Purchase Agreement may be extended in accordance with
its terms), then the Company must redeem, in whole and not in part, all of the Notes on the Special Mandatory Redemption Date at a redemption price (the “Special Mandatory Redemption Price”) equal to 101% of the aggregate principal
amount of the Notes outstanding, plus accrued and unpaid interest from the most recent Interest Payment Date to which interest has been paid or duly provided for or, if no interest has been paid, from the Issue Date to, but excluding, the Special
Mandatory Redemption Date. 
 The Company will mail notice of such Special Mandatory Redemption, with a copy to the Trustee,
within five Business Days after the occurrence of the event triggering such Special Mandatory Redemption to each Holder of Notes at its registered address. 

If money sufficient to pay the Special Mandatory Redemption Price of all of the Notes to be redeemed on the Special Mandatory
Redemption Date is deposited with the Trustee or Paying Agent on or before the Special Mandatory Redemption Date as provided herein and in the Indenture, then on and after such Special Mandatory Redemption Date, interest will cease to accrue on such
Notes. 
  

	 	3.	 Redemption Upon Changes in Withholding Taxes; Additional Amounts 



The provisions of Sections 1501 and 1502 of the Base Indenture and Sections 2.07 and 3.02 of the Supplemental Indenture shall
apply to this series of Notes. 
 Whenever the payment of the principal of or interest or any other amounts on, or in respect
of, this Note is mentioned, in any context, such mention shall be deemed to include mention of the payment of Additional Amounts to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof pursuant to the
terms of the Indenture, and express mention of the payment of Additional Amounts in any provision of this series of Notes shall not be construed as excluding the payment of Additional Amounts in those provisions thereof where such express mention is
not made. 

  
 B-5 














	 	4.	 No Other Redemption 



Except as set forth in Sections 1, 2 and 3 of this Note and in Article 3 of the Supplemental Indenture, the Company may not
redeem the Notes prior to the Maturity Date. 
  

	 	5.	 Change of Control Triggering Event 



If a Change of Control Triggering Event occurs, unless the Notes of this series have become redeemable as described in Sections
3.01 and 3.02 of the Supplemental Indenture, Holders of the Notes of this series will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of their Notes pursuant
to the offer described below (the “Change of Control Offer”) on the terms set forth herein. In the Change of Control Offer, the Company will be required to offer payment in cash equal to 101% of the aggregate principal amount of
Notes repurchased plus accrued and unpaid interest, if any, on the Notes repurchased to the date of purchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, or, at the
Company’s option, prior to the date of the consummation of any Change of Control, but after public announcement of the transaction that constitutes or may constitute the Change of Control, the Company will be required to mail a notice to
Holders of the Notes, with a copy to the Trustee, describing the transaction or transactions that constitute or may constitute the Change of Control Triggering Event and offering to repurchase the Notes on the date specified in the notice, which
date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed (the “Change of Control Payment Date”), pursuant to the procedures required by the Indenture and described in such notice. The notice
shall, if mailed prior to the date of the consummation of the Change of Control, state that the offer to purchase is conditioned on the Change of Control Triggering Event occurring on or prior to the Change of Control Payment Date. 

On the Change of Control Payment Date, the Company will be required, to the extent lawful, to: 

(i)    accept for payment all of the Notes, or portions of the Notes, properly tendered pursuant to
the Change of Control Offer; 
 (ii)    deposit with the Paying Agent an amount equal to the
Change of Control Payment in respect of all of the Notes, or portions of the Notes, properly tendered; and 

(iii)    deliver or cause to be delivered to the Trustee the Notes properly accepted together with
an Officers’ Certificate stating the aggregate principal amount of Notes, or portions of Notes, being repurchased. 

The Paying Agent will promptly mail to each Holder of Notes properly tendered the Change of Control Payment for such Notes, and
the Trustee will promptly authenticate and mail (or cause to be transferred by book-entry) to each such Holder a new Note equal in principal amount to any unpurchased portion of any Notes surrendered; provided that each new Note will be in a
principal amount of $2,000 or an integral multiple of $1,000 in excess thereof. The Company will not be required to make an offer to repurchase the Notes upon a Change of Control Triggering Event if a third party makes such an offer in the manner,
at the times and otherwise in compliance with the requirements for an offer made by the Company and such third party purchases all Notes properly tendered and not withdrawn under its offer. 

  
 B-6 













 In addition, the Company will not repurchase any Notes if there has occurred
and is continuing on the Change of Control Payment Date an Event of Default under the Indenture, other than a default in the payment of the Change of Control Payment upon a Change of Control Triggering Event. 

 

	 	6.	 No Sinking Fund 



The Notes are not entitled to the benefit of any sinking fund. 

 

	 	7.	 Defeasance and Discharge 



The Indenture contains provisions for defeasance and discharge and for defeasance at any time of certain restrictive covenants
and Events of Default with respect to this Note upon compliance with certain conditions set forth in the Indenture. 
  

	 	8.	 Guarantee 



This Note is fully and unconditionally guaranteed by the Guarantor, as provided in Article 14 of the Indenture. 

 

	 	9.	 Modification and Waiver 



The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights
and obligations of the Company and the Guarantor and the rights of the Holders of the Notes of each series to be affected under the Indenture at any time by the Company, the Guarantor and the Trustee with the consent of the Holders of a majority in
principal amount of the Notes at the time Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the Notes of each series at the time Outstanding, on
behalf of the Holders of all Notes of such series, to waive compliance by the Company and the Guarantor with certain provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the
Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such
consent or waiver is made upon this Note. Without notice to or consent of any Holder, the parties thereto may amend or supplement the Indenture and the Notes to, among other things, cure any ambiguity, defect or inconsistency, provide for
uncertificated Notes in addition to or in place of certificated Notes, or make any other change that does not adversely affect the rights of any Holder of a Note. 
  

	 	10.	 Events of Default 



If an Event of Default with respect to the Notes shall occur and be continuing, the principal of the Notes may be declared due
and payable in the manner and with the effect provided in the Indenture. 

  
 B-7 














	 	11.	 Remedies 



As provided in and subject to the provisions of the Indenture, the Holder of this Note shall not have the right to institute
any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect
to the Notes of this series, the Holders of not less than 25% in principal amount of the Notes of this series at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as
Trustee and offered the Trustee reasonable indemnity, and the Trustee shall not have received from the Holders of a majority in principal amount of Notes of this series at the time Outstanding a direction inconsistent with such request, and shall
have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this Note for the enforcement of any payment of principal
hereof or any premium or interest hereon on or after the respective due dates expressed herein. 
 No reference herein to the
Indenture and no provision of this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and any premium and interest on this Note at the times, place and rate, and
in the coin or currency, herein prescribed. 
  

	 	12.	 Transfer and Exchange 



As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Note is registrable in
the Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any place where the principal of and any premium and interest on this Note are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Notes of this series are issuable only in registered form without coupons in denominations of $2,000 or an integral
multiple of $1,000 thereof. As provided in the Indenture and subject to certain limitations therein set forth, Notes of this series are exchangeable for a like aggregate principal amount of Notes of this series and of like tenor of a different
authorized denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Company, the Guarantor, the Trustee and any agent of
the Company, the Guarantor or the Trustee may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and none of the Company, the Guarantor, the Trustee nor any such agent
shall be affected by notice to the contrary. 

  
 B-8 














	 	13.	 Governing Law 



THIS NOTE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE
CONSTRUED IN ACCORDANCE WITH THE LAWS OF SAID STATE. FOR THE AVOIDANCE OF DOUBT, THE APPLICABILITY OF ARTICLES 470-3 to 470-19 OF THE LUXEMBOURG LAW DATED
AUGUST 10, 1915 ON COMMERCIAL COMPANIES, AS AMENDED, SHALL BE EXCLUDED. 
  

	 	14.	 Defined Terms 



All terms used in this Note which are defined in the Indenture shall have the meanings assigned to them in the Indenture. As
used in this Note, the term “Predecessor Note” shall have the meaning assigned to the term “Predecessor Security” in the Indenture. 

  
 B-9 













 ASSIGNMENT 
  

			
		 	FOR VALUE RECEIVED, the undersigned assigns and transfers this Note to:
		
		 	  

		
		 	  

		
		 	(Insert assignee’s social security or tax identification number)
		
		 	  

		
		 	  

		
		 	  

		
		 	(Insert address and zip code of assignee) and irrevocably appoints
		
		 	  

		
		 	  

		
		 	  

		
		 	agent to transfer this Note on the books of the Company. The agent may substitute another to act for him or her.
		
		 	 Date:
                            



			
		
		  	Signature:
                                         
               
		
		  	Signature Guarantee:
                                       


 (Sign exactly as your name appears on the other side of this Note) 

  
 B-10 













 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security
Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in
addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 

  
 B-11 













 SCHEDULE OF INCREASES OR DECREASES IN NOTE 

The initial principal amount of this Note is $            . The following
increases or decreases in the principal amount of this Note have been made: 
  

									
	 Date
	 	 Amount of

decrease in

principal
 amount of
this
 Note
	 	 Amount of

increase in

principal
 amount of
this
 Note
	 	 Principal

amount of this
 Note
following
 such decrease

or increase
	 	 Signature of

authorized
 signatory
of
 Trustee

		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
	  
	 	  
	 	  
	 	  
	 	  



  
 B-12 













 EXHIBIT C 

[IF THIS NOTE IS TO BE A GLOBAL SECURITY, INSERT:] 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO
THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF,
CEDE & CO., HAS AN INTEREST HEREIN. 
 THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED
TO AND IS REGISTERED IN THE NAME OF DTC OR A NOMINEE THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN DTC OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND MAY NOT BE
TRANSFERRED EXCEPT AS A WHOLE BY DTC TO A NOMINEE OF DTC OR BY A NOMINEE OF DTC TO DTC OR ANOTHER NOMINEE OF DTC. 
 DH EUROPE FINANCE II
S.À R.L. 
 2.600% Senior Note due 2029 
  

			
	No.                                 	  	$                            
		
	 	  	CUSIP: 23291K AH8
	 	  	ISIN: US23291KAH86

 DH Europe Finance II S.à r.l., a private limited liability company
(société à responsabilité limitée) duly organized and existing under the laws of Luxembourg, having its registered office at 1 B Heienhaff, L-1736 Senningerberg, Grand
Duchy of Luxembourg and registered with the Luxembourg Trade and Companies Register under number B 235.237 (herein called the “Company,” which term includes any successor Person under the Indenture hereinafter referred to), for
value received, hereby promises to pay to ________________, or registered assigns, the principal sum set forth in the Schedule of Increases or Decreases in Note attached hereto on November 15, 2029, and to pay interest thereon from
November 7, 2019 or from the immediately preceding Interest Payment Date to which interest has been paid or duly provided for, semi-annually in arrears on May 15 and November 15 of each year, commencing May 15, 2020 at the rate
of 2.600% per annum, until the principal hereof is paid or made available for payment. Interest shall be computed on the basis of a 360-day year consisting of twelve
30-day months. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Person in whose name this Note (or one or more
Predecessor Notes) is registered on the Security Register at the close of business on the Regular Record Date for such interest, which shall be May 1 or November 1, whether or not a Business Day, immediately preceding the related Interest
Payment Date, except as provided in Section 2.06 of the Supplemental Indenture. 

  
 C-1 













 Any such interest not so punctually paid or duly provided for will forthwith
cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the payment of such
Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of this Note not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of
any securities exchange on which the Notes of this series may be listed, and upon such notice as may be required by such exchange, all as more fully provided in said Indenture. 

Payment of the principal of (and premium, if any) and interest on this Note will be made at the office or agency of the Company
maintained for that purpose in accordance with the Indenture, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided, however, that at the option of
the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register or by wire transfer to an account maintained by the Person entitled thereto as specified
in the Security Register. 
 This Note is fully and unconditionally guaranteed by Danaher Corporation, a corporation duly
organized and existing under the laws of the State of Delaware (the “Guarantor”), as provided in the Indenture. 

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall
for all purposes have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has
been executed by the Trustee referred to on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its corporate seal. 

 

							
	Dated:                         	 		 	
			
		 		 	DH EUROPE FINANCE II S.À R.L.
				
		 		 	By:	 	 
		 		 	Name:	 	 
		 		 	Title: 	 	 


  
 C-2 













 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Notes of the series designated therein described in the within-mentioned Indenture. 

Dated:
                             

 

			
	THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A.,
	
	as Trustee


			
		
	By:	 	 


			
	Authorized Signatory


  
 C-3 













 REVERSE OF NOTE 

This Note is one of a duly authorized issue of Securities of the Company (herein called the “Notes”), issued
and to be issued in one or more series under a Base Indenture, dated as of September 18, 2019 (as heretofore supplemented, herein called the “Base Indenture”), among the Company, the Guarantor and The Bank of New York Mellon
Trust Company, N.A., as Trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture), as supplemented by the Second Supplemental Indenture, dated as of November 7, 2019 (herein called the
“Supplemental Indenture,” which term shall have the meaning assigned to it in such instrument, and together with the Base Indenture, herein called the “Indenture”) and reference is hereby made to the Indenture for a
statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Guarantor, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be authenticated and delivered.
This Note is one of the series designated on the face hereof initially limited in aggregate principal amount to $800,000,000. The Notes are unsecured general obligations of the Company. 

 

	 	1.	 Optional Redemption 



At any time and from time to time prior to August 15, 2029, the Company shall have the right to redeem the Notes, in whole
or in part, at its option, at a redemption price equal to the greater of: 
 (i) 100% of the principal amount of the
Notes to be redeemed; and 
 (ii) the sum of the present values of the Remaining Scheduled Payments on the Notes to be
redeemed (not including any portion of the payments of interest that will be accrued and unpaid to and including the Redemption Date) discounted to the Redemption Date on a semi-annual basis (assuming a
360-day year consisting of twelve 30-day months) at the applicable Treasury Rate plus 15 basis points, plus accrued and unpaid interest, if any, on the principal amount
of the Notes being redeemed to, but excluding, the Redemption Date. 
 On or after August 15, 2029, the Company shall
have the right, at its option, to redeem the Notes, in whole or in part, at any time and from time to time, at a redemption price equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest, if any, on the
principal amount of the Notes being redeemed to, but excluding, the Redemption Date. 
 The Company will mail (or send
electronically in accordance with applicable Depositary procedures) notice of any redemption to the registered Holders of the Notes to be redeemed not less than 15 nor more than 60 days prior to the Redemption Date. Any notice may, at the discretion
of the Company be subject to the satisfaction or waiver of one or more conditions precedent. In that case, the notice shall state the nature of such condition precedent. If the Notes are only partially redeemed pursuant to Section 3.01 of the
Supplemental Indenture, the Notes to be redeemed will be selected by the Trustee in such manner as in its sole discretion it shall deem appropriate and fair, subject to any applicable Depositary procedures. 

  
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 If money sufficient to pay the redemption price of all of the Notes (or a
portion thereof) to be redeemed on the Redemption Date is deposited with the Trustee or Paying Agent on or before the Redemption Date as provided herein and in the Indenture, then on and after such Redemption Date, interest will cease to accrue on
such Notes (or such portion thereof) called for redemption. 
 In the event of redemption of this Note in part only, a new
Note or Notes for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 
  

	 	2.	 Special Mandatory Redemption 



In the event that the Guarantor does not consummate the GE Biopharma Acquisition on or prior to August 25, 2020 (or such
later date to which the Purchase Agreement may be extended in accordance with its terms) or the Purchase Agreement is terminated at any time prior thereto (or such later date to which the Purchase Agreement may be extended in accordance with
its terms), then the Company must redeem, in whole and not in part, all of the Notes on the Special Mandatory Redemption Date at a redemption price (the “Special Mandatory Redemption Price”) equal to 101% of the aggregate principal
amount of the Notes outstanding, plus accrued and unpaid interest from the most recent Interest Payment Date to which interest has been paid or duly provided for or, if no interest has been paid, from the Issue Date to, but excluding, the Special
Mandatory Redemption Date. 
 The Company will mail notice of such Special Mandatory Redemption, with a copy to the Trustee,
within five Business Days after the occurrence of the event triggering such Special Mandatory Redemption to each Holder of Notes at its registered address. 

If money sufficient to pay the Special Mandatory Redemption Price of all of the Notes to be redeemed on the Special Mandatory
Redemption Date is deposited with the Trustee or Paying Agent on or before the Special Mandatory Redemption Date as provided herein and in the Indenture, then on and after such Special Mandatory Redemption Date, interest will cease to accrue on such
Notes. 
  

	 	3.	 Redemption Upon Changes in Withholding Taxes; Additional Amounts 



The provisions of Sections 1501 and 1502 of the Base Indenture and Sections 2.07 and 3.02 of the Supplemental Indenture shall
apply to this series of Notes. 
 Whenever the payment of the principal of or interest or any other amounts on, or in respect
of, this Note is mentioned, in any context, such mention shall be deemed to include mention of the payment of Additional Amounts to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof pursuant to the
terms of the Indenture, and express mention of the payment of Additional Amounts in any provision of this series of Notes shall not be construed as excluding the payment of Additional Amounts in those provisions thereof where such express mention is
not made. 

  
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	 	4.	 No Other Redemption 



Except as set forth in Sections 1, 2 and 3 of this Note and in Article 3 of the Supplemental Indenture, the Company may not
redeem the Notes prior to the Maturity Date. 
  

	 	5.	 Change of Control Triggering Event 



If a Change of Control Triggering Event occurs, unless the Notes of this series have become redeemable as described in Sections
3.01 and 3.02 of the Supplemental Indenture, Holders of the Notes of this series will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of their Notes pursuant
to the offer described below (the “Change of Control Offer”) on the terms set forth herein. In the Change of Control Offer, the Company will be required to offer payment in cash equal to 101% of the aggregate principal amount of
Notes repurchased plus accrued and unpaid interest, if any, on the Notes repurchased to the date of purchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, or, at the
Company’s option, prior to the date of the consummation of any Change of Control, but after public announcement of the transaction that constitutes or may constitute the Change of Control, the Company will be required to mail a notice to
Holders of the Notes, with a copy to the Trustee, describing the transaction or transactions that constitute or may constitute the Change of Control Triggering Event and offering to repurchase the Notes on the date specified in the notice, which
date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed (the “Change of Control Payment Date”), pursuant to the procedures required by the Indenture and described in such notice. The notice
shall, if mailed prior to the date of the consummation of the Change of Control, state that the offer to purchase is conditioned on the Change of Control Triggering Event occurring on or prior to the Change of Control Payment Date. 

On the Change of Control Payment Date, the Company will be required, to the extent lawful, to: 

(i) accept for payment all of the Notes, or portions of the Notes, properly tendered pursuant to the Change of Control
Offer; 
 (ii) deposit with the Paying Agent an amount equal to the Change of Control Payment in respect of all of the
Notes, or portions of the Notes, properly tendered; and 
 (iii) deliver or cause to be delivered to the Trustee the
Notes properly accepted together with an Officers’ Certificate stating the aggregate principal amount of Notes, or portions of Notes, being repurchased. 

The Paying Agent will promptly mail to each Holder of Notes properly tendered the Change of Control Payment for such Notes, and
the Trustee will promptly authenticate and mail (or cause to be transferred by book-entry) to each such Holder a new Note equal in principal amount to any unpurchased portion of any Notes surrendered; provided that each new Note will be in a
principal amount of $2,000 or an integral multiple of $1,000 in excess thereof. The Company will not be required to make an offer to repurchase the Notes upon a Change of Control Triggering Event if a third party makes such an offer in the manner,
at the times and otherwise in compliance with the requirements for an offer made by the Company and such third party purchases all Notes properly tendered and not withdrawn under its offer. 

  
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 In addition, the Company will not repurchase any Notes if there has occurred
and is continuing on the Change of Control Payment Date an Event of Default under the Indenture, other than a default in the payment of the Change of Control Payment upon a Change of Control Triggering Event. 

 

	 	6.	 No Sinking Fund 



The Notes are not entitled to the benefit of any sinking fund. 

 

	 	7.	 Defeasance and Discharge 



The Indenture contains provisions for defeasance and discharge and for defeasance at any time of certain restrictive covenants
and Events of Default with respect to this Note upon compliance with certain conditions set forth in the Indenture. 
  

	 	8.	 Guarantee 



This Note is fully and unconditionally guaranteed by the Guarantor, as provided in Article 14 of the Indenture. 

 

	 	9.	 Modification and Waiver 



The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights
and obligations of the Company and the Guarantor and the rights of the Holders of the Notes of each series to be affected under the Indenture at any time by the Company, the Guarantor and the Trustee with the consent of the Holders of a majority in
principal amount of the Notes at the time Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the Notes of each series at the time Outstanding, on
behalf of the Holders of all Notes of such series, to waive compliance by the Company and the Guarantor with certain provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the
Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such
consent or waiver is made upon this Note. Without notice to or consent of any Holder, the parties thereto may amend or supplement the Indenture and the Notes to, among other things, cure any ambiguity, defect or inconsistency, provide for
uncertificated Notes in addition to or in place of certificated Notes, or make any other change that does not adversely affect the rights of any Holder of a Note. 
  

	 	10.	 Events of Default 



If an Event of Default with respect to the Notes shall occur and be continuing, the principal of the Notes may be declared due
and payable in the manner and with the effect provided in the Indenture. 

  
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	 	11.	 Remedies 



As provided in and subject to the provisions of the Indenture, the Holder of this Note shall not have the right to institute
any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect
to the Notes of this series, the Holders of not less than 25% in principal amount of the Notes of this series at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as
Trustee and offered the Trustee reasonable indemnity, and the Trustee shall not have received from the Holders of a majority in principal amount of Notes of this series at the time Outstanding a direction inconsistent with such request, and shall
have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this Note for the enforcement of any payment of principal
hereof or any premium or interest hereon on or after the respective due dates expressed herein. 
 No reference herein to the
Indenture and no provision of this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and any premium and interest on this Note at the times, place and rate, and
in the coin or currency, herein prescribed. 
  

	 	12.	 Transfer and Exchange 



As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Note is registrable in
the Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any place where the principal of and any premium and interest on this Note are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Notes of this series are issuable only in registered form without coupons in denominations of $2,000 or an integral
multiple of $1,000 thereof. As provided in the Indenture and subject to certain limitations therein set forth, Notes of this series are exchangeable for a like aggregate principal amount of Notes of this series and of like tenor of a different
authorized denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Company, the Guarantor, the Trustee and any agent of
the Company, the Guarantor or the Trustee may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and none of the Company, the Guarantor, the Trustee nor any such agent
shall be affected by notice to the contrary. 

  
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	 	13.	 Governing Law 



THIS NOTE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE
CONSTRUED IN ACCORDANCE WITH THE LAWS OF SAID STATE. FOR THE AVOIDANCE OF DOUBT, THE APPLICABILITY OF ARTICLES 470-3 to 470-19 OF THE LUXEMBOURG LAW DATED
AUGUST 10, 1915 ON COMMERCIAL COMPANIES, AS AMENDED, SHALL BE EXCLUDED. 
  

	 	14.	 Defined Terms 



All terms used in this Note which are defined in the Indenture shall have the meanings assigned to them in the Indenture. As
used in this Note, the term “Predecessor Note” shall have the meaning assigned to the term “Predecessor Security” in the Indenture. 

  
 C-9 













 ASSIGNMENT 
  

			
		 	FOR VALUE RECEIVED, the undersigned assigns and transfers this Note to:
		
		 	  

		
		 	  

		
		 	(Insert assignee’s social security or tax identification number)
		
		 	  

		
		 	  

		
		 	  

		
		 	(Insert address and zip code of assignee) and irrevocably appoints
		
		 	  

		
		 	  

		
		 	  

		
		 	agent to transfer this Note on the books of the Company. The agent may substitute another to act for him or her.
		
		 	 Date:
                            



			
		
		  	 Signature:
                                         
           

		
		  	 Signature Guarantee:
                                   


 (Sign exactly as your name appears on the other side of this Note) 

  
 C-10 













 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security
Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in
addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 

  
 C-11 













 SCHEDULE OF INCREASES OR DECREASES IN NOTE 

The initial principal amount of this Note is $            . The following
increases or decreases in the principal amount of this Note have been made: 
  

									
	 Date
	 	 Amount of

decrease in

principal
 amount of
this
 Note
	 	 Amount of

increase in

principal
 amount of
this
 Note
	  	 Principal

amount of this
 Note
following
 such decrease

or increase
	  	 Signature of

authorized
 signatory
of
 Trustee

		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
	  
	 	  
	 	  
	  	  
	  	  



  
 C-12 













 EXHIBIT D 

[IF THIS NOTE IS TO BE A GLOBAL SECURITY, INSERT:] 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO
THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF,
CEDE & CO., HAS AN INTEREST HEREIN. 
 THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED
TO AND IS REGISTERED IN THE NAME OF DTC OR A NOMINEE THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN DTC OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND MAY NOT BE
TRANSFERRED EXCEPT AS A WHOLE BY DTC TO A NOMINEE OF DTC OR BY A NOMINEE OF DTC TO DTC OR ANOTHER NOMINEE OF DTC. 
 DH EUROPE FINANCE II
S.À R.L. 
 3.250% Senior Note due 2039 
  

					
	No.                                     	  		  	$                             
			
		  		  	CUSIP: 23291K AJ4
		  		  	ISIN: US23291KAJ43

 DH Europe Finance II S.à r.l., a private limited liability company
(société à responsabilité limitée) duly organized and existing under the laws of Luxembourg, having its registered office at 1 B Heienhaff, L-1736 Senningerberg, Grand
Duchy of Luxembourg and registered with the Luxembourg Trade and Companies Register under number B 235.237 (herein called the “Company,” which term includes any successor Person under the Indenture hereinafter referred to), for
value received, hereby promises to pay to ________________, or registered assigns, the principal sum set forth in the Schedule of Increases or Decreases in Note attached hereto on November 15, 2039, and to pay interest thereon from
November 7, 2019 or from the immediately preceding Interest Payment Date to which interest has been paid or duly provided for, semi-annually in arrears on May 15 and November 15 of each year, commencing May 15, 2020 at the rate
of 3.250% per annum, until the principal hereof is paid or made available for payment. Interest shall be computed on the basis of a 360-day year consisting of twelve
30-day months. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Person in whose name this Note (or one or more
Predecessor Notes) is registered on the Security Register at the close of business on the Regular Record Date for such interest, which shall be May 1 or November 1, whether or not a Business Day, immediately preceding the related Interest
Payment Date, except as provided in Section 2.06 of the Supplemental Indenture. 

  
 D-1 













 Any such interest not so punctually paid or duly provided for will forthwith
cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the payment of such
Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of this Note not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of
any securities exchange on which the Notes of this series may be listed, and upon such notice as may be required by such exchange, all as more fully provided in said Indenture. 

Payment of the principal of (and premium, if any) and interest on this Note will be made at the office or agency of the Company
maintained for that purpose in accordance with the Indenture, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided, however, that at the option of
the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register or by wire transfer to an account maintained by the Person entitled thereto as specified
in the Security Register. 
 This Note is fully and unconditionally guaranteed by Danaher Corporation, a corporation duly
organized and existing under the laws of the State of Delaware (the “Guarantor”), as provided in the Indenture. 

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall
for all purposes have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has
been executed by the Trustee referred to on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its corporate seal. 

Dated:
                             

 

			
	DH EUROPE FINANCE II S.À R.L.
		
	By:	 	              

	Name:	 	              

	Title:	 	  




  
 D-2 













 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Notes of the series designated therein described in the within-mentioned Indenture. 

Dated:
                         

THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., 

as Trustee 
 By:
                                        

 Authorized Signatory 

  
 D-3 













 REVERSE OF NOTE 

This Note is one of a duly authorized issue of Securities of the Company (herein called the “Notes”), issued
and to be issued in one or more series under a Base Indenture, dated as of September 18, 2019 (as heretofore supplemented, herein called the “Base Indenture”), among the Company, the Guarantor and The Bank of New York Mellon
Trust Company, N.A., as Trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture), as supplemented by the Second Supplemental Indenture, dated as of November 7, 2019 (herein called the
“Supplemental Indenture,” which term shall have the meaning assigned to it in such instrument, and together with the Base Indenture, herein called the “Indenture”) and reference is hereby made to the Indenture for a
statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Guarantor, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be authenticated and delivered.
This Note is one of the series designated on the face hereof initially limited in aggregate principal amount to $900,000,000. The Notes are unsecured general obligations of the Company. 

 

	 	1.	 Optional Redemption 



At any time and from time to time prior to May 15, 2039, the Company shall have the right to redeem the Notes, in whole or
in part, at its option, at a redemption price equal to the greater of: 
 (i)    100% of the
principal amount of the Notes to be redeemed; and 
 (ii)    the sum of the present values of the
Remaining Scheduled Payments on the Notes to be redeemed (not including any portion of the payments of interest that will be accrued and unpaid to and including the Redemption Date) discounted to the Redemption Date on a semi-annual basis (assuming
a 360-day year consisting of twelve 30-day months) at the applicable Treasury Rate plus 15 basis points, plus accrued and unpaid interest, if any, on the principal
amount of the Notes being redeemed to, but excluding, the Redemption Date. 
 On or after May 15, 2039, the Company
shall have the right, at its option, to redeem the Notes, in whole or in part, at any time and from time to time, at a redemption price equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest, if any, on
the principal amount of the Notes being redeemed to, but excluding, the Redemption Date. 
 The Company will mail (or send
electronically in accordance with applicable Depositary procedures) notice of any redemption to the registered Holders of the Notes to be redeemed not less than 15 nor more than 60 days prior to the Redemption Date. Any notice may, at the discretion
of the Company be subject to the satisfaction or waiver of one or more conditions precedent. In that case, the notice shall state the nature of such condition precedent. If the Notes are only partially redeemed pursuant to Section 3.01 of the
Supplemental Indenture, the Notes to be redeemed will be selected by the Trustee in such manner as in its sole discretion it shall deem appropriate and fair, subject to any applicable Depositary procedures. 

  
 D-4 













 If money sufficient to pay the redemption price of all of the Notes (or a
portion thereof) to be redeemed on the Redemption Date is deposited with the Trustee or Paying Agent on or before the Redemption Date as provided herein and in the Indenture, then on and after such Redemption Date, interest will cease to accrue on
such Notes (or such portion thereof) called for redemption. 
 In the event of redemption of this Note in part only, a new
Note or Notes for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 
  

	 	2.	 Special Mandatory Redemption 



In the event that the Guarantor does not consummate the GE Biopharma Acquisition on or prior to August 25, 2020 (or such
later date to which the Purchase Agreement may be extended in accordance with its terms) or the Purchase Agreement is terminated at any time prior thereto (or such later date to which the Purchase Agreement may be extended in accordance with
its terms), then the Company must redeem, in whole and not in part, all of the Notes on the Special Mandatory Redemption Date at a redemption price (the “Special Mandatory Redemption Price”) equal to 101% of the aggregate principal
amount of the Notes outstanding, plus accrued and unpaid interest from the most recent Interest Payment Date to which interest has been paid or duly provided for or, if no interest has been paid, from the Issue Date to, but excluding, the Special
Mandatory Redemption Date. 
 The Company will mail notice of such Special Mandatory Redemption, with a copy to the Trustee,
within five Business Days after the occurrence of the event triggering such Special Mandatory Redemption to each Holder of Notes at its registered address. 

If money sufficient to pay the Special Mandatory Redemption Price of all of the Notes to be redeemed on the Special Mandatory
Redemption Date is deposited with the Trustee or Paying Agent on or before the Special Mandatory Redemption Date as provided herein and in the Indenture, then on and after such Special Mandatory Redemption Date, interest will cease to accrue on such
Notes. 
  

	 	3.	 Redemption Upon Changes in Withholding Taxes; Additional Amounts 



The provisions of Sections 1501 and 1502 of the Base Indenture and Sections 2.07 and 3.02 of the Supplemental Indenture shall
apply to this series of Notes. 
 Whenever the payment of the principal of or interest or any other amounts on, or in
respect of, this Note is mentioned, in any context, such mention shall be deemed to include mention of the payment of Additional Amounts to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof
pursuant to the terms of the Indenture, and express mention of the payment of Additional Amounts in any provision of this series of Notes shall not be construed as excluding the payment of Additional Amounts in those provisions thereof where such
express mention is not made. 

  
 D-5 














	 	4.	 No Other Redemption 



Except as set forth in Sections 1, 2 and 3 of this Note and in Article 3 of the Supplemental Indenture, the Company may not
redeem the Notes prior to the Maturity Date. 
  

	 	5.	 Change of Control Triggering Event 



If a Change of Control Triggering Event occurs, unless the Notes of this series have become redeemable as described in Sections
3.01 and 3.02 of the Supplemental Indenture, Holders of the Notes of this series will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of their Notes pursuant
to the offer described below (the “Change of Control Offer”) on the terms set forth herein. In the Change of Control Offer, the Company will be required to offer payment in cash equal to 101% of the aggregate principal amount of
Notes repurchased plus accrued and unpaid interest, if any, on the Notes repurchased to the date of purchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, or, at the
Company’s option, prior to the date of the consummation of any Change of Control, but after public announcement of the transaction that constitutes or may constitute the Change of Control, the Company will be required to mail a notice to
Holders of the Notes, with a copy to the Trustee, describing the transaction or transactions that constitute or may constitute the Change of Control Triggering Event and offering to repurchase the Notes on the date specified in the notice, which
date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed (the “Change of Control Payment Date”), pursuant to the procedures required by the Indenture and described in such notice. The notice
shall, if mailed prior to the date of the consummation of the Change of Control, state that the offer to purchase is conditioned on the Change of Control Triggering Event occurring on or prior to the Change of Control Payment Date. 

On the Change of Control Payment Date, the Company will be required, to the extent lawful, to: 

(i)    accept for payment all of the Notes, or portions of the Notes, properly tendered pursuant to
the Change of Control Offer; 
 (ii)    deposit with the Paying Agent an amount equal to the
Change of Control Payment in respect of all of the Notes, or portions of the Notes, properly tendered; and 

(iii)    deliver or cause to be delivered to the Trustee the Notes properly accepted together with
an Officers’ Certificate stating the aggregate principal amount of Notes, or portions of Notes, being repurchased. 

The Paying Agent will promptly mail to each Holder of Notes properly tendered the Change of Control Payment for such Notes, and
the Trustee will promptly authenticate and mail (or cause to be transferred by book-entry) to each such Holder a new Note equal in principal amount to any unpurchased portion of any Notes surrendered; provided that each new Note will be in a
principal amount of $2,000 or an integral multiple of $1,000 in excess thereof. The Company will not be required to make an offer to repurchase the Notes upon a Change of Control Triggering Event if a third party makes such an offer in the manner,
at the times and otherwise in compliance with the requirements for an offer made by the Company and such third party purchases all Notes properly tendered and not withdrawn under its offer. 

  
 D-6 













 In addition, the Company will not repurchase any Notes if there has occurred
and is continuing on the Change of Control Payment Date an Event of Default under the Indenture, other than a default in the payment of the Change of Control Payment upon a Change of Control Triggering Event. 

 

	 	6.    No	 Sinking Fund 



The Notes are not entitled to the benefit of any sinking fund. 

 

	 	7.    Defeasance	 and Discharge 



The Indenture contains provisions for defeasance and discharge and for defeasance at any time of certain restrictive covenants
and Events of Default with respect to this Note upon compliance with certain conditions set forth in the Indenture. 
  

	 	8.    Guarantee	 



This Note is fully and unconditionally guaranteed by the Guarantor, as provided in Article 14 of the Indenture. 

 

	 	9.    Modification	 and Waiver 



The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights
and obligations of the Company and the Guarantor and the rights of the Holders of the Notes of each series to be affected under the Indenture at any time by the Company, the Guarantor and the Trustee with the consent of the Holders of a majority in
principal amount of the Notes at the time Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the Notes of each series at the time Outstanding, on
behalf of the Holders of all Notes of such series, to waive compliance by the Company and the Guarantor with certain provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the
Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such
consent or waiver is made upon this Note. Without notice to or consent of any Holder, the parties thereto may amend or supplement the Indenture and the Notes to, among other things, cure any ambiguity, defect or inconsistency, provide for
uncertificated Notes in addition to or in place of certificated Notes, or make any other change that does not adversely affect the rights of any Holder of a Note. 
  

	 	10.    Events	 of Default 



If an Event of Default with respect to the Notes shall occur and be continuing, the principal of the Notes may be declared due
and payable in the manner and with the effect provided in the Indenture. 

  
 D-7 














	 	11.	 Remedies 



As provided in and subject to the provisions of the Indenture, the Holder of this Note shall not have the right to institute
any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect
to the Notes of this series, the Holders of not less than 25% in principal amount of the Notes of this series at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as
Trustee and offered the Trustee reasonable indemnity, and the Trustee shall not have received from the Holders of a majority in principal amount of Notes of this series at the time Outstanding a direction inconsistent with such request, and shall
have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this Note for the enforcement of any payment of principal
hereof or any premium or interest hereon on or after the respective due dates expressed herein. 
 No reference herein to the
Indenture and no provision of this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and any premium and interest on this Note at the times, place and rate, and
in the coin or currency, herein prescribed. 
  

	 	12.	 Transfer and Exchange 



As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Note is registrable in
the Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any place where the principal of and any premium and interest on this Note are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Notes of this series are issuable only in registered form without coupons in denominations of $2,000 or an integral
multiple of $1,000 thereof. As provided in the Indenture and subject to certain limitations therein set forth, Notes of this series are exchangeable for a like aggregate principal amount of Notes of this series and of like tenor of a different
authorized denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Company, the Guarantor, the Trustee and any agent of
the Company, the Guarantor or the Trustee may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and none of the Company, the Guarantor, the Trustee nor any such agent
shall be affected by notice to the contrary. 

  
 D-8 














	 	13.	 Governing Law 



THIS NOTE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE
CONSTRUED IN ACCORDANCE WITH THE LAWS OF SAID STATE. FOR THE AVOIDANCE OF DOUBT, THE APPLICABILITY OF ARTICLES 470-3 to 470-19 OF THE LUXEMBOURG LAW DATED
AUGUST 10, 1915 ON COMMERCIAL COMPANIES, AS AMENDED, SHALL BE EXCLUDED. 
  

	 	14.	 Defined Terms 



All terms used in this Note which are defined in the Indenture shall have the meanings assigned to them in the Indenture. As
used in this Note, the term “Predecessor Note” shall have the meaning assigned to the term “Predecessor Security” in the Indenture. 

  
 D-9 













 ASSIGNMENT 
  

			
		 	FOR VALUE RECEIVED, the undersigned assigns and transfers this Note to:
		
		 	  

		
		 	  

		
		 	(Insert assignee’s social security or tax identification number)
		
		 	  

		
		 	  

		
		 	  

		
		 	(Insert address and zip code of assignee) and irrevocably appoints
		
		 	  

		
		 	  

		
		 	  

		
		 	agent to transfer this Note on the books of the Company. The agent may substitute another to act for him or her.
		
		 	 Date:
                            



			
		
		  	 Signature:
                                         
           

		
		  	 Signature Guarantee:
                                   


 (Sign exactly as your name appears on the other side of this Note) 

  
 D-10 













 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security
Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in
addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 

  
 D-11 













 SCHEDULE OF INCREASES OR DECREASES IN NOTE 

The initial principal amount of this Note is $            . The following
increases or decreases in the principal amount of this Note have been made: 
  

									
	 Date
	 	 Amount of

decrease in

principal
 amount of
this
 Note
	 	 Amount of

increase in

principal
 amount of
this
 Note
	  	 Principal

amount of this
 Note
following
 such decrease

or increase
	  	 Signature of

authorized
 signatory
of
 Trustee

		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
	  
	 	  
	 	  
	  	  
	  	  



  
 D-12 













 EXHIBIT E 

[IF THIS NOTE IS TO BE A GLOBAL SECURITY, INSERT:] 

UNLESS THIS SECURITY IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO
THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF,
CEDE & CO., HAS AN INTEREST HEREIN. 
 THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED
TO AND IS REGISTERED IN THE NAME OF DTC OR A NOMINEE THEREOF. THIS SECURITY IS EXCHANGEABLE FOR SECURITIES REGISTERED IN THE NAME OF A PERSON OTHER THAN DTC OR ITS NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND MAY NOT BE
TRANSFERRED EXCEPT AS A WHOLE BY DTC TO A NOMINEE OF DTC OR BY A NOMINEE OF DTC TO DTC OR ANOTHER NOMINEE OF DTC. 
 DH EUROPE FINANCE II
S.À R.L. 
 3.400% Senior Note due 2049 
  

					
	No.                                     	  		  	$                             
			
		  		  	CUSIP: 23291K AK1
		  		  	ISIN: US23291KAJ43

 DH Europe Finance II S.à r.l., a private limited liability company
(société à responsabilité limitée) duly organized and existing under the laws of Luxembourg, having its registered office at 1 B Heienhaff, L-1736 Senningerberg, Grand
Duchy of Luxembourg and registered with the Luxembourg Trade and Companies Register under number B 235.237 (herein called the “Company,” which term includes any successor Person under the Indenture hereinafter referred to), for
value received, hereby promises to pay to ________________, or registered assigns, the principal sum set forth in the Schedule of Increases or Decreases in Note attached hereto on November 15, 2049, and to pay interest thereon from
November 7, 2019 or from the immediately preceding Interest Payment Date to which interest has been paid or duly provided for, semi-annually in arrears on May 15 and November 15 of each year, commencing May 15, 2020 at the rate
of 3.400% per annum, until the principal hereof is paid or made available for payment. Interest shall be computed on the basis of a 360-day year consisting of twelve
30-day months. The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date will, as provided in such Indenture, be paid to the Person in whose name this Note (or one or more
Predecessor Notes) is registered on the Security Register at the close of business on the Regular Record Date for such interest, which shall be May 1 or November 1, whether or not a Business Day, immediately preceding the related Interest
Payment Date, except as provided in Section 2.06 of the Supplemental Indenture. 

  
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 Any such interest not so punctually paid or duly provided for will forthwith
cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of business on a Special Record Date for the payment of such
Defaulted Interest to be fixed by the Trustee, notice whereof shall be given to Holders of this Note not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of
any securities exchange on which the Notes of this series may be listed, and upon such notice as may be required by such exchange, all as more fully provided in said Indenture. 

Payment of the principal of (and premium, if any) and interest on this Note will be made at the office or agency of the Company
maintained for that purpose in accordance with the Indenture, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided, however, that at the option of
the Company, payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register or by wire transfer to an account maintained by the Person entitled thereto as specified
in the Security Register. 
 This Note is fully and unconditionally guaranteed by Danaher Corporation, a corporation duly
organized and existing under the laws of the State of Delaware (the “Guarantor”), as provided in the Indenture. 

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall
for all purposes have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has
been executed by the Trustee referred to on the reverse hereof by manual signature, this Note shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed under its corporate seal. 

Dated:
                         

 

			
	DH EUROPE FINANCE II S.À R.L.
		
	By:	 	              

	Name:	 	              

	Title:	 	  




  
 E-2 













 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Notes of the series designated therein described in the within-mentioned Indenture. 

Dated:
                         

THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., 

as Trustee 
 By:
                                         
    
 Authorized Signatory 

  
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 REVERSE OF NOTE 

This Note is one of a duly authorized issue of Securities of the Company (herein called the “Notes”), issued
and to be issued in one or more series under a Base Indenture, dated as of September 18, 2019 (as heretofore supplemented, herein called the “Base Indenture”), among the Company, the Guarantor and The Bank of New York Mellon
Trust Company, N.A., as Trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture), as supplemented by the Second Supplemental Indenture, dated as of November 7, 2019 (herein called the
“Supplemental Indenture,” which term shall have the meaning assigned to it in such instrument, and together with the Base Indenture, herein called the “Indenture”) and reference is hereby made to the Indenture for a
statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Guarantor, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be authenticated and delivered.
This Note is one of the series designated on the face hereof initially limited in aggregate principal amount to $900,000,000. The Notes are unsecured general obligations of the Company. 

 

	 	1.	 Optional Redemption 



At any time and from time to time prior to May 15, 2049, the Company shall have the right to redeem the Notes, in whole or
in part, at its option, at a redemption price equal to the greater of: 
 (i) 100% of the principal amount of the
Notes to be redeemed; and 
 (ii) the sum of the present values of the Remaining Scheduled Payments on the Notes to be
redeemed (not including any portion of the payments of interest that will be accrued and unpaid to and including the Redemption Date) discounted to the Redemption Date on a semi-annual basis (assuming a
360-day year consisting of twelve 30-day months) at the applicable Treasury Rate plus 20 basis points, plus accrued and unpaid interest, if any, on the principal amount
of the Notes being redeemed to, but excluding, the Redemption Date. 
 On or after May 15, 2049, the Company shall have
the right, at its option, to redeem the Notes, in whole or in part, at any time and from time to time, at a redemption price equal to 100% of the principal amount of the Notes to be redeemed, plus accrued and unpaid interest, if any, on the
principal amount of the Notes being redeemed to, but excluding, the Redemption Date. 
 The Company will mail (or send
electronically in accordance with applicable Depositary procedures) notice of any redemption to the registered Holders of the Notes to be redeemed not less than 15 nor more than 60 days prior to the Redemption Date. Any notice may, at the discretion
of the Company be subject to the satisfaction or waiver of one or more conditions precedent. In that case, the notice shall state the nature of such condition precedent. If the Notes are only partially redeemed pursuant to Section 3.01 of the
Supplemental Indenture, the Notes to be redeemed will be selected by the Trustee in such manner as in its sole discretion it shall deem appropriate and fair, subject to any applicable Depositary procedures. 

  
 E-4 













 If money sufficient to pay the redemption price of all of the Notes (or a
portion thereof) to be redeemed on the Redemption Date is deposited with the Trustee or Paying Agent on or before the Redemption Date as provided herein and in the Indenture, then on and after such Redemption Date, interest will cease to accrue on
such Notes (or such portion thereof) called for redemption. 
 In the event of redemption of this Note in part only, a new
Note or Notes for the unredeemed portion hereof shall be issued in the name of the Holder hereof upon the cancellation hereof. 
  

	 	2.	 Special Mandatory Redemption 



In the event that the Guarantor does not consummate the GE Biopharma Acquisition on or prior to August 25, 2020 (or such
later date to which the Purchase Agreement may be extended in accordance with its terms) or the Purchase Agreement is terminated at any time prior thereto (or such later date to which the Purchase Agreement may be extended in accordance with
its terms), then the Company must redeem, in whole and not in part, all of the Notes on the Special Mandatory Redemption Date at a redemption price (the “Special Mandatory Redemption Price”) equal to 101% of the aggregate principal
amount of the Notes outstanding, plus accrued and unpaid interest from the most recent Interest Payment Date to which interest has been paid or duly provided for or, if no interest has been paid, from the Issue Date to, but excluding, the Special
Mandatory Redemption Date. 
 The Company will mail notice of such Special Mandatory Redemption, with a copy to the Trustee,
within five Business Days after the occurrence of the event triggering such Special Mandatory Redemption to each Holder of Notes at its registered address. 

If money sufficient to pay the Special Mandatory Redemption Price of all of the Notes to be redeemed on the Special Mandatory
Redemption Date is deposited with the Trustee or Paying Agent on or before the Special Mandatory Redemption Date as provided herein and in the Indenture, then on and after such Special Mandatory Redemption Date, interest will cease to accrue on such
Notes. 
  

	 	3.	 Redemption Upon Changes in Withholding Taxes; Additional Amounts 



The provisions of Sections 1501 and 1502 of the Base Indenture and Sections 2.07 and 3.02 of the Supplemental Indenture shall
apply to this series of Notes. 
 Whenever the payment of the principal of or interest or any other amounts on, or in respect
of, this Note is mentioned, in any context, such mention shall be deemed to include mention of the payment of Additional Amounts to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof pursuant to the
terms of the Indenture, and express mention of the payment of Additional Amounts in any provision of this series of Notes shall not be construed as excluding the payment of Additional Amounts in those provisions thereof where such express mention is
not made. 

  
 E-5 














	 	4.	 No Other Redemption 



Except as set forth in Sections 1, 2 and 3 of this Note and in Article 3 of the Supplemental Indenture, the Company may not
redeem the Notes prior to the Maturity Date. 
  

	 	5.	 Change of Control Triggering Event 



If a Change of Control Triggering Event occurs, unless the Notes of this series have become redeemable as described in Sections
3.01 and 3.02 of the Supplemental Indenture, Holders of the Notes of this series will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of their Notes pursuant
to the offer described below (the “Change of Control Offer”) on the terms set forth herein. In the Change of Control Offer, the Company will be required to offer payment in cash equal to 101% of the aggregate principal amount of
Notes repurchased plus accrued and unpaid interest, if any, on the Notes repurchased to the date of purchase (the “Change of Control Payment”). Within 30 days following any Change of Control Triggering Event, or, at the
Company’s option, prior to the date of the consummation of any Change of Control, but after public announcement of the transaction that constitutes or may constitute the Change of Control, the Company will be required to mail a notice to
Holders of the Notes, with a copy to the Trustee, describing the transaction or transactions that constitute or may constitute the Change of Control Triggering Event and offering to repurchase the Notes on the date specified in the notice, which
date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed (the “Change of Control Payment Date”), pursuant to the procedures required by the Indenture and described in such notice. The notice
shall, if mailed prior to the date of the consummation of the Change of Control, state that the offer to purchase is conditioned on the Change of Control Triggering Event occurring on or prior to the Change of Control Payment Date. 

On the Change of Control Payment Date, the Company will be required, to the extent lawful, to: 

(i) accept for payment all of the Notes, or portions of the Notes, properly tendered pursuant to the Change of Control
Offer; 
 (ii) deposit with the Paying Agent an amount equal to the Change of Control Payment in respect of all of the
Notes, or portions of the Notes, properly tendered; and 
 (iii) deliver or cause to be delivered to the Trustee the
Notes properly accepted together with an Officers’ Certificate stating the aggregate principal amount of Notes, or portions of Notes, being repurchased. 

The Paying Agent will promptly mail to each Holder of Notes properly tendered the Change of Control Payment for such Notes, and
the Trustee will promptly authenticate and mail (or cause to be transferred by book-entry) to each such Holder a new Note equal in principal amount to any unpurchased portion of any Notes surrendered; provided that each new Note will be in a
principal amount of $2,000 or an integral multiple of $1,000 in excess thereof. The Company will not be required to make an offer to repurchase the Notes upon a Change of Control Triggering Event if a third party makes such an offer in the manner,
at the times and otherwise in compliance with the requirements for an offer made by the Company and such third party purchases all Notes properly tendered and not withdrawn under its offer. 

  
 E-6 













 In addition, the Company will not repurchase any Notes if there has occurred
and is continuing on the Change of Control Payment Date an Event of Default under the Indenture, other than a default in the payment of the Change of Control Payment upon a Change of Control Triggering Event. 

 

	 	6.	 No Sinking Fund 



The Notes are not entitled to the benefit of any sinking fund. 

 

	 	7.	 Defeasance and Discharge 



The Indenture contains provisions for defeasance and discharge and for defeasance at any time of certain restrictive covenants
and Events of Default with respect to this Note upon compliance with certain conditions set forth in the Indenture. 
  

	 	8.	 Guarantee 



This Note is fully and unconditionally guaranteed by the Guarantor, as provided in Article 14 of the Indenture. 

 

	 	9.	 Modification and Waiver 



The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights
and obligations of the Company and the Guarantor and the rights of the Holders of the Notes of each series to be affected under the Indenture at any time by the Company, the Guarantor and the Trustee with the consent of the Holders of a majority in
principal amount of the Notes at the time Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the Notes of each series at the time Outstanding, on
behalf of the Holders of all Notes of such series, to waive compliance by the Company and the Guarantor with certain provisions of the Indenture and certain past defaults under the Indenture and their consequences. Any such consent or waiver by the
Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such
consent or waiver is made upon this Note. Without notice to or consent of any Holder, the parties thereto may amend or supplement the Indenture and the Notes to, among other things, cure any ambiguity, defect or inconsistency, provide for
uncertificated Notes in addition to or in place of certificated Notes, or make any other change that does not adversely affect the rights of any Holder of a Note. 
  

	 	10.	 Events of Default 



If an Event of Default with respect to the Notes shall occur and be continuing, the principal of the Notes may be declared due
and payable in the manner and with the effect provided in the Indenture. 

  
 E-7 














	 	11.	 Remedies 



As provided in and subject to the provisions of the Indenture, the Holder of this Note shall not have the right to institute
any proceeding with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of Default with respect
to the Notes of this series, the Holders of not less than 25% in principal amount of the Notes of this series at the time Outstanding shall have made written request to the Trustee to institute proceedings in respect of such Event of Default as
Trustee and offered the Trustee reasonable indemnity, and the Trustee shall not have received from the Holders of a majority in principal amount of Notes of this series at the time Outstanding a direction inconsistent with such request, and shall
have failed to institute any such proceeding, for 60 days after receipt of such notice, request and offer of indemnity. The foregoing shall not apply to any suit instituted by the Holder of this Note for the enforcement of any payment of principal
hereof or any premium or interest hereon on or after the respective due dates expressed herein. 
 No reference herein to
the Indenture and no provision of this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of and any premium and interest on this Note at the times, place and rate,
and in the coin or currency, herein prescribed. 
  

	 	12.	 Transfer and Exchange 



As provided in the Indenture and subject to certain limitations therein set forth, the transfer of this Note is registrable in
the Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any place where the principal of and any premium and interest on this Note are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of
authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Notes of this series are issuable only in registered form without coupons in denominations of $2,000 or an integral
multiple of $1,000 thereof. As provided in the Indenture and subject to certain limitations therein set forth, Notes of this series are exchangeable for a like aggregate principal amount of Notes of this series and of like tenor of a different
authorized denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for any such
registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 

Prior to due presentment of this Note for registration of transfer, the Company, the Guarantor, the Trustee and any agent of
the Company, the Guarantor or the Trustee may treat the Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and none of the Company, the Guarantor, the Trustee nor any such agent
shall be affected by notice to the contrary. 

  
 E-8 














	 	13.	 Governing Law 



THIS NOTE SHALL BE DEEMED TO BE A CONTRACT MADE UNDER THE LAWS OF THE STATE OF NEW YORK, AND FOR ALL PURPOSES SHALL BE
CONSTRUED IN ACCORDANCE WITH THE LAWS OF SAID STATE. FOR THE AVOIDANCE OF DOUBT, THE APPLICABILITY OF ARTICLES 470-3 to 470-19 OF THE LUXEMBOURG LAW DATED
AUGUST 10, 1915 ON COMMERCIAL COMPANIES, AS AMENDED, SHALL BE EXCLUDED. 
  

	 	14.	 Defined Terms 



All terms used in this Note which are defined in the Indenture shall have the meanings assigned to them in the Indenture. As
used in this Note, the term “Predecessor Note” shall have the meaning assigned to the term “Predecessor Security” in the Indenture. 

  
 E-9 













 ASSIGNMENT 
  

			
		 	FOR VALUE RECEIVED, the undersigned assigns and transfers this Note to:
		
		 	  

		
		 	  

		
		 	(Insert assignee’s social security or tax identification number)
		
		 	  

		
		 	  

		
		 	  

		
		 	(Insert address and zip code of assignee) and irrevocably appoints
		
		 	  

		
		 	  

		
		 	  

		
		 	agent to transfer this Note on the books of the Company. The agent may substitute another to act for him or her.
		
		 	 Date:
                            



			
		
		  	 Signature:
                                         
           

		
		  	 Signature Guarantee:
                                   


 (Sign exactly as your name appears on the other side of this Note) 

  
 E-10 













 SIGNATURE GUARANTEE 

Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements of the Security
Registrar, which requirements include membership or participation in the Security Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be determined by the Security Registrar in
addition to, or in substitution for, STAMP, all in accordance with the Securities Exchange Act of 1934, as amended. 

  
 E-11 













 SCHEDULE OF INCREASES OR DECREASES IN NOTE 

The initial principal amount of this Note is $            . The following
increases or decreases in the principal amount of this Note have been made: 
  

									
	 Date
	 	 Amount of

decrease in

principal
 amount of
this
 Note
	 	 Amount of

increase in

principal
 amount of
this
 Note
	  	 Principal

amount of this
 Note
following
 such decrease

or increase
	  	 Signature of

authorized
 signatory
of
 Trustee

		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
		 		 		  		  	
	  
	 	  
	 	  
	  	  
	  	  



  
 E-12 













 EXHIBIT F 

[FORM OF GUARANTEE] 
 GUARANTEE

 For value received, the undersigned (the “Guarantor”), to the extent set forth in and subject to the
terms of the Indenture, dated as of September 18, 2019 (as heretofore supplemented, the “Base Indenture”), among DH Europe Finance II S.à r.l., a private limited liability company, société à
responsabilité limitée, duly organized and existing under the laws of Luxembourg, having its registered office at 1 B Heienhaff, L-1736 Senningerberg, Grand Duchy of Luxembourg and registered
with the Luxembourg Trade and Companies Register under number B 235.237 (the “Company”), the Guarantor and The Bank of New York Mellon Trust Company, N.A., as Trustee (herein called the Trustee, which term includes any successor
trustee under the Indenture) and the Second Supplemental Indenture, among the Company, the Guarantor and the Trustee (the “Supplemental Indenture,” and together with the Base Indenture, the “Indenture”), irrevocably
and unconditionally guarantees to each Holder and to the Trustee and its successors and assigns (1) the full and punctual payment when due, whether at Stated Maturity, by acceleration, by redemption or otherwise, of all obligations of the
Company under the Indenture (including obligations to the Trustee) and the Notes, whether for payment of principal of, interest on, premium, if any, or Additional Amounts, if any, on the Notes and all other monetary obligations of the Company under
the Indenture and the Notes and (2) the full and punctual performance within applicable grace periods of all other obligations of the Company whether for fees, expenses, indemnification or otherwise under the Indenture and the Notes. 

The obligations of the Guarantor to the Holders and to the Trustee pursuant to this Guarantee and the Indenture are expressly
set forth in Article 14 of the Indenture, and reference is hereby made to the Indenture for the precise terms and limitations of this Guarantee. Each Holder of the Notes to which this Guarantee is endorsed, by accepting such Notes, agrees to and
shall be bound by such provisions. 
 All terms used and not otherwise defined in this Guarantee which are defined in the
Indenture shall have the meanings assigned to them in the Indenture. 
 IN WITNESS WHEREOF, the Guarantor has caused this
Guarantee to be signed by a duly authorized officer. 
  

			
	DANAHER CORPORATION, as Guarantor
	
	By:                                   
                                     
	Authorized Signatory



  
 F-1