UNITED STATES
               SECURITIES AND EXCHANGE COMMISSION
                     Washington, D.C. 20549
                                
                           FORM 10-Q/A
                                
                         Amendment No. 1
                                
 (X) Quarterly Report Pursuant to Section 13 or 15(d) of the
     Securities Exchange Act of 1934 for the quarterly period
     ended March 31, 1998

                               or

 ( ) Transition Report Pursuant to Section 13 or 15(d) of the
     Securities Exchange Act of 1934 for the transition period
     from __________ to __________

Commission File Number 1-6247


                         ALZA CORPORATION
     (Exact name of registrant as specified in its charter)


Delaware                                               77-0142070
(State or other jurisdiction of                  (I.R.S. Employer
incorporation or organization)                Identification No.)

                       950 Page Mill Road
                         P.O. Box 10950
                Palo Alto, California 94303-0802
            (Address of principal executive offices)

Registrant's telephone number, including area code (650) 494-5000


     Indicate by check mark whether the registrant (1) has filed
all reports required to be filed by Section 13 or 15(d) of the
Securities Exchange Act of 1934 during the preceding 12 months
(or for such shorter period that the registrant was required to
file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes (X)  No ( )



Number of shares outstanding of each of the registrant's classes
of common stock as of April 30, 1998:



Common Stock, $.01 par value - 86,420,910 shares






                        ALZA CORPORATION
                 FORM 10-Q for the Quarter Ended
                         March 31, 1998
                                
                                
                              INDEX


Part I. Financial Information


Item 1. Financial Statements

     Condensed Consolidated Statement of Income                3
     Condensed Consolidated Balance Sheet                      4
     Condensed Consolidated Statement of Cash Flows            5
     Notes to Financial Statements                           6-8


Item 2. Management's Discussion and Analysis of
       Financial Condition and Results of Operations        9-14


Signatures                                                    15


PART I.   FINANCIAL INFORMATION

Item 1.   Financial Statements

                        ALZA CORPORATION
   Condensed Consolidated Statement of Operations (unaudited)
             (In millions, except per share amounts)

                                           Quarter Ended
                                             March 31,
                                      1998                1997
                                  ______________________________

Revenues:
  Net sales                         $   54.4           $   27.5
  Royalties, fees and other             50.0               44.2
  Research and development              26.3               33.8
                                  ______________________________
     Total revenues                    130.7              105.5

Expenses:
  Costs of products shipped             29.4               19.7
  Research and development              34.2               35.0
  Selling, general and
     administrative                     16.2               11.6
                                  ______________________________
     Total expenses                     79.8               66.3
                                  ______________________________

  Operating income                      50.9               39.2

Interest expense                        14.1               13.7
Interest and other income               (6.5)             (16.9)
                                  ______________________________

     Net interest and other
       expense (income)                  7.6               (3.2)
                                  ______________________________
Income before
  income taxes                          43.3               42.4

Provision for income taxes              15.0               16.1
                                  ______________________________
Net income                          $   28.3           $   26.3
                                  ==============================

Earnings per share
  Basic                             $   0.33           $   0.31
                                  ============================== 
  Diluted                           $   0.32           $   0.30
                                  ==============================

See accompanying notes.


                        ALZA Corporation
        Condensed Consolidated Balance Sheet (unaudited)
                          (In millions)
                                        March 31,   December 31,
                                           1998         1997
                                      __________________________
ASSETS
Current assets:
  Cash and cash equivalents             $    82.6    $     65.0
  Short-term investments                     99.5         109.2
  Receivables, net                          125.2         119.2
  Inventories, at cost:
   Raw materials                              9.0          16.5
   Work in process                           11.0           8.5
   Finished goods                            14.0          12.8
                                      __________________________
     Total inventories                       34.0          37.8
  Prepaid expenses and other
   current assets                            28.4          26.8
                                      __________________________
     Total current assets                   369.7         358.0

Property, plant and equipment               431.9         401.8
Less accumulated depreciation
  and amortization                          (99.8)        (91.4)
                                      __________________________
  Net property, plant and equipment         332.1         310.4
Investments in long-term securities         363.5         361.6
Other assets                                338.1         339.2
                                      __________________________
     Total assets                       $ 1,403.4    $  1,369.2
                                      ==========================
LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
  Accounts payable                      $    27.2    $     56.9
  Accrued liabilities                        52.2          45.9
  Other current liabilities                   5.2           1.8
                                      __________________________
     Total current liabilities               84.6         104.6

5% convertible subordinated debentures      500.0         500.0
5 1/4% zero coupon convertible
  subordinated debentures                   407.8         402.6
Other long-term liabilities                  64.2          60.8

Stockholders' equity:
  Common stock and additional
   paid-in capital                          399.8         382.4
  Accumulated other comprehensive
   income                                    (4.9)         (4.8)
  Retained earnings (deficit)               (48.1)        (76.4)
                                      __________________________
     Total stockholders' equity             346.8         301.2
                                      __________________________
     Total liabilities and
      stockholders' equity              $ 1,403.4    $  1,369.2
                                      ==========================
See accompanying notes.



                        ALZA CORPORATION
   Condensed Consolidated Statement of Cash Flows (unaudited)
                          (In millions)

                                                Quarter Ended
                                                  March 31,
                                                1998       1997
                                               _________________
CASH FLOWS FROM OPERATING ACTIVITIES:
 Net income                                   $  28.3   $  26.3
 Non-cash adjustments to reconcile net income
  to net cash provided by operating activities:
   Depreciation and amortization                  9.9       6.4
   Amortization of product payments               2.6       0.3
     Interest on 5 1/4% zero coupon convertible
     subordinated debentures                      5.2       5.0
  (Increase) decrease in current assets          (3.7)      2.1
   Decrease in current liabilities              (23.3)     (2.9)
   Other                                         (0.6)      1.5
                                               _________________
Net cash provided by operating activities        18.4      38.7

CASH FLOWS FROM INVESTING ACTIVITIES:
 Sales and maturities of available-for-sale
  securities                                    101.1     201.2
 Purchases of available-for-sale securities     (93.4)   (189.3)
 Capital expenditures                           (12.6)     (4.4)
 Other investing activities                     (10.4)      2.2
                                               _________________
Net cash (used in) provided by
 investing activities                           (15.3)      9.7

CASH FLOWS FROM FINANCING ACTIVITIES:
 Issuances of common stock                       17.4       5.3
 Principal payments on long-term debt            (2.9)     (1.1)
                                               _________________
Net cash provided by financing activities        14.5       4.2
                                               _________________
Net increase in cash and cash equivalents        17.6      52.6

Cash and cash equivalents at
 beginning of period                             65.0     187.7
                                               _________________
Cash and cash equivalents at end of period    $  82.6   $ 240.3
							     =================

See accompanying notes.


ALZA CORPORATION
Notes to Condensed Consolidated Financial Statements (unaudited)
----------------------------------------------------------------

1. BASIS OF PRESENTATION

    The information at March 31, 1998 and for the quarters ended
March 31, 1998 and 1997 is unaudited, and includes all
adjustments (consisting only of normal recurring adjustments)
that the management of ALZA Corporation ("ALZA") believes
necessary for fair presentation of the results for the periods
presented.  Interim results are not necessarily indicative of
results for the full year.  The condensed consolidated balance
sheet for December 31, 1997 was derived from the audited balance
sheet.  The condensed consolidated financial statements should be
read in conjunction with the audited consolidated financial
statements and accompanying notes for the year ended
December 31, 1997 included in ALZA's 1997 Annual Report to
Stockholders.

Comprehensive Income
--------------------

    As of January 1, 1998, ALZA adopted Statement of Financial
Accounting Standards No. 130, "Reporting Comprehensive Income"
("SFAS 130"), which establishes standards for reporting
comprehensive income and its components.  Comprehensive income
includes net income plus other comprehensive income, which, for
ALZA, primarily comprises net unrealized gains or losses on
available-for-sale securities.  Other comprehensive income was
not material for the quarters ended March 31, 1998 and 1997.
Total comprehensive income for the quarters ended March 31, 1998
and 1997 approximates net income for these periods.  The adoption
of SFAS 130 had no impact on ALZA's results of operations or
financial condition.

Supplemental Disclosures of Cash Flow Information
-------------------------------------------------

Noncash Investing and Financing       Quarter Ended March 31,
  Activities (In millions)            1998                1997
_________________________________________________________________
Investment in low-income housing
  in exchange for long-term debt    $ 10.1             $   6.6

Acquisition of building in lieu of
  repayment of note receivable        17.5                 -


Recently Issued Accounting Pronouncement
----------------------------------------

     In June 1997, the Financial Accounting Standards Board
issued Statement of Financial Accounting Standards No. 131,
"Disclosures about Segments of an Enterprise and Related
Information" ("SFAS 131"). SFAS 131 establishes standards for
annual and interim disclosures of operating segments, products
and services, geographic areas and major customers.  SFAS 131 is
effective beginning with the 1998 fiscal year end financial
statements, and will be applied retroactively, for comparison
purposes, to the 1998 quarters in the 1999 quarterly disclosures.
ALZA is in the process of evaluating the disclosure requirements
of the new standard, the adoption of which will have no impact on
ALZA's results of operations or financial condition.


2. PER SHARE INFORMATION

     Basic earnings per share is calculated by dividing net
income by the weighted average common shares outstanding for the
period.  Diluted earnings per share is calculated by dividing net
income, as adjusted, by the weighted average common shares
outstanding for the period plus the dilutive effect of stock
options, warrants and convertible securities.

     The following table sets forth the computation of ALZA's
basic and diluted earnings per share (in millions, except per
share amounts):
                                      Quarter Ended March 31,
                                      1998                1997
_________________________________________________________________
NUMERATOR:
Basic
  Net income                      $   28.3             $  26.3
=================================================================
Diluted
  Net income                      $   28.3             $  26.3
  Interest on 5 1/4% zero coupon
    convertible subordinated
    debentures, net of tax             3.5                 3.2
_________________________________________________________________
  Adjusted net income             $   31.8             $  29.5
=================================================================
DENOMINATOR:
Basic
  Weighted average shares             85.9                84.8
=================================================================
Diluted
  Weighted average shares             85.9                84.8
  Effect of dilutive securities:
   Employee stock options              1.4                 0.7
   5 1/4% zero coupon convertible
     subordinated debentures          12.3                12.3
_________________________________________________________________
  Weighted average shares and
    assumed conversions               99.6                97.8
=================================================================
Basic earnings per share          $    0.33            $   0.31
=================================================================
Diluted earnings per share        $    0.32            $   0.30
=================================================================
     Options to purchase 120,400 shares of common stock were
excluded from the diluted earnings per share calculation for the
three months ended March 31, 1998 because the exercise price of
the options was greater than the average market price of the
common shares during the quarter, and therefore the effect of
including those options would have been anti-dilutive.  ALZA's
outstanding 5% convertible subordinated debentures due 2006 were
not included in the diluted earnings per share calculation for
the periods presented, as their inclusion would have been anti-
dilutive.


3. CRESCENDO PHARMACEUTICALS CORPORATION

    Under the Development Agreement between ALZA and Crescendo
Pharmaceuticals Corporation ("Crescendo"), a related party, ALZA
recorded product development revenues of $19.9 million for the
quarter  ended March 31, 1998.  As of March 31, 1998, disclosed
products in development with Crescendo were OROS-registered
trademark- oxybutynin, DUROS-trademark- leuprolide, OROS-
registered trademark- methylphenidate, E-TRANS-trademark- LHRH, E-
TRANS-trademark- Macroflux-trademark- insulin and E-TRANS-
trademark- fentanyl (chronic pain).

   Under the Technology License Agreement between ALZA and
Crescendo, ALZA recorded technology fee revenue from Crescendo of
$3.0 million for the three months ended March 31, 1998.

   ALZA has an option to acquire an exclusive, royalty-bearing
license to each product developed by Crescendo under the
Development Agreement.  The option is exercisable on a product-by-
product, country-by-country, basis. Under Crescendo's Restated
Certificate of Incorporation, ALZA has the right to purchase all
(but not less than all) of the Class A Common Stock of Crescendo
at a price based upon a pre-established formula.

Item 2.  Management's Discussion and Analysis of Financial
         Condition and Results of Operations

Notice Concerning Forward-Looking Statements

     Some of the statements made in this Form 10-Q are forward-
looking in nature, including, without limitation, plans
concerning the commercialization of products, statements
concerning potential product sales, future costs of products
shipped (and gross margins), associated sales and marketing
expenses, plans concerning development of products and other
statements that are not historical facts.  The occurrence of the
events described, and the achievement of the intended results,
are subject to various risk factors that could cause ALZA's
actual results to be materially different than those presented,
some or all of which are not predictable or within ALZA's
control. The significant risks related to ALZA's business are
described in ALZA's Annual Report on Form 10-K for the year ended
December 31, 1997.


RESULTS OF OPERATIONS

SUMMARY
                                      Quarter Ended March 31,
(In millions, except per share amounts)1998              1997
_________________________________________________________________
Revenues                            $ 130.7            $ 105.5
_________________________________________________________________
Operating Income                       50.9               39.2
_________________________________________________________________
Net Income                             28.3               26.3
_________________________________________________________________
Earnings per Share (diluted)           0.32               0.30
_________________________________________________________________

     For the quarter ended March 31, 1998, ALZA's net income and
operating income increased 8% and 30%, respectively, compared to
the same quarter of 1997.  These increases were due primarily to
a significant increase in the sales of ALZA-marketed products,
reflecting sales of Elmiron-registered trademark- (pentosan
polysulfate sodium) and Mycelex-registered trademark-
(clotrimazole) Troche, which ALZA began marketing in the second
half of 1997, and increased sales of Ethyol-registered trademark-
(amifostine).  ALZA's gross margin on net sales improved to 46%
for the first quarter of 1998, compared to 28% for the first
quarter of 1997, reflecting the increased sales of ALZA-marketed
products.  Also contributing to higher income for the first
quarter of 1998 was a 13% increase in royalties, fees and other
revenues, reflecting an increase in licensing fees.  These
increases were partially offset by a 22% decline in research and
development revenues and substantially lower interest income,
discussed below.

NET SALES AND COSTS OF PRODUCTS SHIPPED

Net Sales
                                      Quarter Ended March 31,
(Dollars in millions)                  1998               1997
_________________________________________________________________
ALZA-marketed products
 Ethyol-registered trademark-       $   8.1             $   3.5
 Elmiron-registered trademark-          7.0                  -
 Mycelex-registered trademark- Troche   5.9                  -
 Testoderm-registered trademark- line   2.0                 1.2
 Other                                  6.4                 2.2
_________________________________________________________________
Total ALZA-marketed products           29.4                 6.9
Contract manufacturing                 25.0                20.6
_________________________________________________________________
  Total net sales                   $  54.4            $   27.5
=================================================================
Percentage of total revenues           42%                 26%
ALZA-marketed products as a percentage
  of net sales                         54%                 25%
_________________________________________________________________

     Net sales for the first quarter of 1998 increased 98%
compared to the first quarter of 1997, primarily reflecting the
significant increase in the sales of ALZA-marketed products, the
rights to several of which ALZA acquired in the second half of
1997.  The U.S. rights to Mycelex Troche were acquired by ALZA in
July 1997, and the U.S. and Canadian rights to Elmiron were
acquired in October 1997.  Sales of Elmiron were impacted by a
buy-in by wholesalers prior to a price increase late in the first
quarter of 1998.  In addition, sales of Ethyol increased in the
first quarter of 1998 compared with the first quarter of 1997 due
in part to a buy-in by wholesalers prior to a price increase that
became effective at the end of the quarter.  Net sales for the
first quarter of 1998 include initial sales of Testoderm-
registered trademark- TTS (testosterone), which was launched in
March 1998.  The timing and quantities of orders for ALZA-
marketed products may vary from quarter to quarter due to factors
such as demand for the products, ordering patterns of
wholesalers, and introduction and sales of competing products.

     Net sales from contract manufacturing increased for the
first quarter of 1998, compared to the first quarter of 1997,
primarily due to higher shipments of Duragesic-registered
trademark- (fentanyl) to Janssen, Nicoderm-registered trademark-
and NicoDerm-registered trademark- CQ-trademark- (nicotine) to
Hoechst Marion Roussel, Inc. and SmithKline Beecham p.l.c.
("SKB"), respectively, and Covera-HS-trademark- (verapamil) to
G.D. Searle & Co. The timing and quantities of orders for
products marketed by client companies are not within ALZA's
control.  Net sales to client companies therefore can be expected
to fluctuate from period to period, sometimes significantly,
depending on the volume, mix and timing of orders of products
shipped to client companies, and in some quarters, due to the
shipment of launch quantities of products to the clients.

     Costs of products shipped increased to $29.4 million for the
quarter ended March 31, 1998, compared to $19.7 million for the
corresponding quarter of 1997, reflecting the significant
increase in net sales.

                                      Quarter Ended March 31,
                                       1998             1997
_________________________________________________________________
Gross margin as a
   percentage of net sales (1)          46%              28%
_________________________________________________________________
(1) Gross margin is net sales less costs of products shipped.

     The increase in ALZA's gross margin in the first quarter of
1998, compared to the first quarter of 1997, was due to the
substantial increase in sales of ALZA-marketed products.  ALZA
expects its gross margin, as a percentage of net sales, to
increase over the longer term, although quarter-to-quarter
fluctuations will continue to occur. Higher gross margins may be
achieved through continuing the proportionate increase in the
sales of ALZA-marketed products (as compared to sales from
contract manufacturing), increased utilization of capacity and
greater operating efficiencies.


ROYALTIES, FEES AND OTHER REVENUES

                                      Quarter Ended March 31,
(Dollars in millions)                 1998                1997
_________________________________________________________________
Royalties, fees and other revenues $   50.0            $  44.2
Percentage of total revenues           38%                42%
_________________________________________________________________

     Royalties, fees and other revenues increased 13% for the
first quarter of 1998, compared to the corresponding quarter of
1997, resulting from an increase in licensing fees.  Licensing
fees for the first quarter of 1998 included fees related to a
technology licensing agreement with Alkermes, Inc. for ALZA's
RingCap-trademark- and Dose Sipping technologies, and technology
fee revenue of $3.0 million from Crescendo.

     Royalties on sales of Glucotrol XL-registered trademark-
(glipizide) by Pfizer Inc. ("Pfizer") and Duragesic by Janssen
increased for the first quarter of 1998, compared to the first
quarter of 1997, and were offset by decreased royalties on sales
of Procardia XL-registered trademark- (nifedipine) by Pfizer,
Transderm-Nitro-registered trademark- (nitroglycerin) by Novartis
Pharmaceuticals Corporation and NicoDerm CQ by SKB.

     Sales of Procardia XL, as reported by Pfizer, decreased 19%
for the first quarter of 1998, compared to the same period in
1997. Several companies have filed Abbreviated New Drug
Applications with the U.S. Food and Drug Administration ("FDA")
requesting clearance to market generic sustained-release
nifedipine products.  Pfizer is involved in litigation concerning
patent infringement and regulatory requirements, in which Pfizer
is seeking to enjoin the introduction of such generic nifedipine
products. It is not possible to predict the timing and amount of
the negative impact on sales of Procardia XL that could result
from competition from these or other potential sustained-release
nifedipine products.

     During the next several years, ALZA intends to continue to
reduce its dependence on royalties and fees by further expanding
ALZA's sales and marketing activities and by directly marketing
and selling more products.  However, there can be no assurance
that ALZA will be successful in undertaking this expansion, or
that any expanded sales and marketing activities will be
successful, due to factors such as the risks associated with
developing, clinically testing and obtaining regulatory clearance
of products for ALZA marketing, the difficulties and costs
associated with acquiring products from third parties for ALZA to
market, the length of the regulatory approval process, the
uncertainties surrounding the acceptance of new products by the
intended markets, the marketing of competitive products, the
risks relating to patents and proprietary rights and the current
health care cost containment environment in the United States.
ALZA expects that, in the near term, royalties on sales by
clients of currently marketed products will continue to be a
substantial contributor to net income.


RESEARCH AND DEVELOPMENT

Research and Development Revenues
                                         Quarter Ended March 31,
(Dollars in millions)                     1998             1997
__________________________________________________________________
Crescendo Pharmaceuticals Corporation     $ 19.9        $   -
Therapeutic Discovery Corporation (1)        -             23.4
Other clients                                6.4           10.4
__________________________________________________________________
  Total research and development revenues $ 26.3$          33.8
=================================================================
Percentage of total revenues                 20%            32%
_________________________________________________________________
(1) Purchased by ALZA in the third quarter of 1997.

     Research and development revenues declined 22% in the first
quarter of 1998 compared to the first quarter of 1997, reflecting
a decrease in product development activities under agreements
with client companies.


Research and Development Expenses
                                      Quarter Ended March 31,
(Dollars in millions)                 1998                1997
_________________________________________________________________
Research and development expenses   $ 34.2              $ 35.0
As a percentage of total revenues     26%                 33%
_________________________________________________________________

    Research and development expenses decreased 2% in the first
quarter of 1998, compared to the same period in 1997. This
decline reflects the lower level of development activity for
client companies, substantially offset by higher internal
research and development costs.

SELLING, GENERAL AND ADMINISTRATIVE EXPENSES

                                      Quarter Ended March 31,
 (Dollars in millions)                 1998               1997
_________________________________________________________________
Sales and marketing expenses        $  10.8            $   6.0
General and administrative expenses     2.8                5.3
Amortization of product acquisition
 payments                               2.6                0.3
_________________________________________________________________
 Total selling, general and
   administrative expenses          $  16.2            $  11.6
=================================================================
As a percentage of total revenues       12%                11%
_________________________________________________________________

     Selling, general and administrative expenses increased 41%
in the first quarter of 1998, compared to the first quarter of
1997, as a result of expanded sales and marketing activities and
the added amortization of payments for product rights acquired in
the second half of 1997.  The decline in general and
administrative expenses in the first quarter of 1998 compared
with the first quarter of 1997 was due to an increase in the cash
surrender value of life insurance policies, which reduced
expenses, and the allocation of certain computer system expenses
from general and administrative expenses to other expense
categories.


NET INTEREST
                                      Quarter Ended March 31,
 (In millions)                         1998               1997
_________________________________________________________________
Interest expense                    $  14.1            $  13.7
Interest and other income              (6.5)             (16.9)
_________________________________________________________________
  Net interest expense (income)     $   7.6            $  (3.2)
_________________________________________________________________

     Interest income declined in the first quarter of 1998,
compared to the first quarter of 1997, due to lower cash balances
as a result of the purchase of Therapeutic Discovery Corporation,
the formation of Crescendo and several product acquisitions, all
of which occurred in the second half of 1997.  Interest expense
was higher in the first quarter of 1998 compared to the same
period of 1997, primarily due to accreted interest on ALZA's
outstanding 5 1/4% zero coupon convertible subordinated
debentures due in 2014.

Effective Tax Rate

     ALZA's annual effective combined federal and state income
tax rate for 1998 is estimated to be 35%.  The effective tax rate
for the year ended 1997 was 35%.  For the first quarter of 1998,
the effective income tax rate was 35%, compared to 38% for the
first quarter of 1997.


LIQUIDITY AND CAPITAL RESOURCES
                                    March 31,      December 31,
(In millions)                           1998            1997
_________________________________________________________________
Working capital                      $  285.1       $  253.4
Cash and investments                    545.6          535.8
Total assets                          1,403.4        1,369.2
Long-term debt                          907.8          902.6

                                      Quarter Ended March 31,
(In millions)                           1998            1997
_________________________________________________________________
Net cash provided by
  operating activities               $  18.4        $   38.7
Capital expenditures                    12.6             4.4
_________________________________________________________________

     Cash provided by operating activities for the three months
ended March 31, 1998 declined from the prior year primarily due
to a $21.5 million payment to Janssen related to a modified
development agreement, effective December 31, 1997, for an E-
TRANS-trademark- fentanyl product for the treatment of acute
pain.  ALZA's capital spending for the first quarter of 1998 was
$12.6 million for additions to facilities and equipment to
support its research, development and manufacturing activities,
compared to capital spending of $4.4 million in the same period
of 1997.  While ALZA believes its current facilities and
equipment are sufficient to meet its current operating
requirements, ALZA is expanding its facilities and equipment to
support its medium-term and long-term requirements.  Capital
expenditures during the remainder of 1998 are expected to
continue to increase over 1997 levels.

     ALZA believes that its existing cash and investment balances
are adequate to fund its cash needs for 1998 and beyond.  In
addition, should the need arise, ALZA believes it would be able
to borrow additional funds or otherwise raise additional capital.
ALZA may consider using its capital to make strategic investments
or to acquire or license technology or products.  ALZA may also
enter into strategic alliances with third parties that could
provide access to additional capital.


                           SIGNATURES

    Pursuant to the requirements of the Securities Exchange Act
of 1934, the registrant has duly caused this report to be signed
on its behalf by the undersigned thereunto duly authorized.


                                   ALZA CORPORATION



Date: February 11, 1999       By:            /s/ E. Mario
                                           Dr. Ernest Mario
                                          Chairman and Chief
                                          Executive Officer



Date: February 11, 1999       By:        /s/ Bruce C. Cozadd
                                           Bruce C. Cozadd
                                        Senior Vice President and
                                        Chief Financial Officer