SEER Cancer Statistics Review 1975-2008 National Cancer Institute

Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. (http://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

The Hispanic and Non-Hispanic mortality trends exclude deaths from CT, DC, ME, MD, MN, NH, NY, ND, OK and VT.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08

SEER 9 Delay-Adjusted Incidencea, 1975-2008

All Races 1975-81 0.7 1981-03 -1.1* 2003-08 0.4 -0.3 0.4

White 1975-03 -0.9* 2003-08 0.8 0.1 0.8

Black 1975-84 2.5* 1984-08 -2.6* -2.6* -2.6*

SEER 13 Delay-Adjusted Incidenceb, 1992-2008

All Races 1992-06 -1.2* 2006-08 3.0 -0.2 0.9

White 1992-06 -0.9* 2006-08 3.8 0.1 1.4

Black 1992-08 -2.6* -2.6* -2.6*

SEER 9 Observed Incidencea, 1975-2008

All Races 1975-79 1.4 1979-08 -1.0* -1.0* -1.0*

White 1975-83 0.1 1983-00 -1.2* 2000-08 0.1 0.0 0.1

Black 1975-84 2.5* 1984-08 -2.6* -2.6* -2.6*

SEER 13 Observed Incidenceb, 1992-2008

All Races 1992-08 -1.0* -1.0* -1.0*

White 1992-08 -0.8* -0.8* -0.8*

White NHef 1992-08 -0.5* -0.5* -0.5*

Black 1992-08 -2.8* -2.8* -2.8*

Black NHef 1992-08 -2.8* -2.8* -2.8*

APIe 1992-08 -0.9* -0.9* -0.9*

AI/ANeg 1992-08 -3.5* -3.5* -3.5*

Hispanicf 1992-08 -1.8* -1.8* -1.8*

U.S. Cancer Mortalityc, 1975-2008

All Races

White

Black

U.S. Cancer Mortalityc, 1992-2008

All Races

White

White NHef

Black

Black NHef

APIe

AI/ANeg

Hispanicf

Table 20.1

Cancer of the Oral Cavity and Pharynx (Invasive)

Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2008 With up to Five Joinpoints, 1992-2008 With up to Three Joinpoints,

Both Sexes by Race/Ethnicity
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. (http://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint over the time range of 1975-2008.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2004-08

Cancer of the Tongue

All Races Both Sexes 1975-99 0.4* 1999-08 2.2* 2.2*

All Races Male 1975-99 0.3 1999-08 2.6* 2.6*

All Races Female 1975-08 0.4* 0.4*

White Male 1975-98 0.5* 1998-08 3.0* 3.0*

White Female 1975-08 0.6* 0.6*

Black Male 1975-89 1.3 1989-08 -2.8* -2.8*

Black Female 1975-08 -1.4* -1.4*

Cancer of the Floor of Mouth, Gum and Other Mouth

All Races Both Sexes 1975-83 0.9 1983-08 -2.5* -2.5*

All Races Male 1975-83 0.7 1983-08 -2.9* -2.9*

All Races Female 1975-85 0.5 1985-08 -2.0* -2.0*

White Male 1975-84 -0.2 1984-08 -2.7* -2.7*

White Female 1975-86 0.6 1986-08 -2.1* -2.1*

Black Male 1975-77 54.7* 1977-98 -2.3* 1998-08 -9.1* -9.1*

Black Female 1975-08 -1.7* -1.7*

Cancer of the Oropharynx and Tonsil

All Races Both Sexes 1975-99 -0.1 1999-08 3.2* 3.2*

All Races Male 1975-99 0.4 1999-08 3.6* 3.6*

All Races Female 1975-08 -1.1* -1.1*

White Male 1975-99 0.5* 1999-08 4.9* 4.9*

White Female 1975-08 -0.9* -0.9*

Black Male 1975-08 -0.5 -0.5

Black Female 1975-08 -2.0* -2.0*

Cancer of the Salivary Gland

All Races Both Sexes 1975-08 0.5* 0.5*

All Races Male 1975-08 0.6* 0.6*

All Races Female 1975-08 0.3* 0.3*

White Male 1975-08 0.7* 0.7*

White Female 1975-08 0.3 0.3

Black Male 1975-99 2.6* 1999-08 -7.3* -7.3*

Black Female 1975-08 0.6 0.6

Cancer of the Lip

All Races Both Sexes 1975-98 -3.2* 1998-08 -5.9* -5.9*

All Races Male 1975-97 -3.7* 1997-08 -6.6* -6.6*

All Races Female 1975-01 -0.1 2001-08 -5.5* -5.5*

White Male 1975-96 -3.4* 1996-08 -6.4* -6.4*

White Female 1975-98 0.3 1998-08 -3.8* -3.8*

Black Male - - -

Black Female - - -

Table 20.2

Cancer of the Oral Cavity and Pharynx for Selected Subsites (Invasive)

Trends in SEER 9 Observed Incidencea Using the Joinpoint Regression Program,

1975-2008 With up to Five Joinpoints,

By Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. (http://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

The Hispanic and Non-Hispanic mortality trends exclude deaths from CT, DC, ME, MD, MN, NH, NY, ND, OK and VT.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08

SEER 9 Delay-Adjusted Incidencea, 1975-2008

All Races 1975-83 -0.1 1983-01 -1.5* 2001-08 0.1 -0.3 0.1

White 1975-01 -1.2* 2001-08 0.5 0.1 0.5

Black 1975-87 1.9* 1987-08 -3.2* -3.2* -3.2*

SEER 13 Delay-Adjusted Incidenceb, 1992-2008

All Races 1992-06 -1.4* 2006-08 3.8 -0.2 1.2

White 1992-06 -1.0* 2006-08 4.3 0.1 1.6

Black 1992-08 -3.1* -3.1* -3.1*

SEER 9 Observed Incidencea, 1975-2008

All Races 1975-83 -0.1 1983-01 -1.5* 2001-08 -0.1 -0.4 -0.1

White 1975-01 -1.2* 2001-08 0.2 -0.1 0.2

Black 1975-87 1.9* 1987-08 -3.2* -3.2* -3.2*

SEER 13 Observed Incidenceb, 1992-2008

All Races 1992-06 -1.4* 2006-08 3.0 -0.4 0.8

White 1992-06 -1.1* 2006-08 3.3 -0.1 1.1

White NHef 1992-99 -1.5* 1999-08 0.1 0.1 0.1

Black 1992-08 -3.2* -3.2* -3.2*

Black NHef 1992-08 -3.2* -3.2* -3.2*

APIe 1992-08 -1.0* -1.0* -1.0*

AI/ANeg 1992-08 -5.9* -5.9* -5.9*

Hispanicf 1992-08 -2.1* -2.1* -2.1*

U.S. Cancer Mortalityc, 1975-2008

All Races

White

Black

U.S. Cancer Mortalityc, 1992-2008

All Races

White

White NHef

Black

Black NHef

APIe

AI/ANeg

Hispanicf

Table 20.3

Cancer of the Oral Cavity and Pharynx (Invasive)

Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2008 With up to Five Joinpoints, 1992-2008 With up to Three Joinpoints,

Males by Race/Ethnicity
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. (http://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska

Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

The Hispanic and Non-Hispanic mortality trends exclude deaths from CT, DC, ME, MD, MN, NH, NY, ND, OK and VT.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08

SEER 9 Delay-Adjusted Incidencea, 1975-2008

All Races 1975-80 2.4 1980-08 -0.9* -0.9* -0.9*

White 1975-81 1.9 1981-08 -0.8* -0.8* -0.8*

Black 1975-08 -1.4* -1.4* -1.4*

SEER 13 Delay-Adjusted Incidenceb, 1992-2008

All Races 1992-08 -1.0* -1.0* -1.0*

White 1992-08 -1.0* -1.0* -1.0*

Black 1992-08 -1.5* -1.5* -1.5*

SEER 9 Observed Incidencea, 1975-2008

All Races 1975-80 2.5* 1980-08 -0.9* -0.9* -0.9*

White 1975-81 2.0 1981-08 -0.9* -0.9* -0.9*

Black 1975-08 -1.5* -1.5* -1.5*

SEER 13 Observed Incidenceb, 1992-2008

All Races 1992-08 -1.0* -1.0* -1.0*

White 1992-08 -1.1* -1.1* -1.1*

White NHef 1992-08 -0.9* -0.9* -0.9*

Black 1992-08 -1.6* -1.6* -1.6*

Black NHef 1992-08 -1.5* -1.5* -1.5*

APIe 1992-08 -0.5 -0.5 -0.5

AI/ANeg 1992-08 0.7 0.7 0.7

Hispanicf 1992-08 -1.4* -1.4* -1.4*

U.S. Cancer Mortalityc, 1975-2008

All Races

White

Black

U.S. Cancer Mortalityc, 1992-2008

All Races

White

White NHef

Black

Black NHef

APIe

AI/ANeg

Hispanicf

Table 20.4

Cancer of the Oral Cavity and Pharynx (Invasive)

Trends in SEER Incidenceab and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2008 With up to Five Joinpoints, 1992-2008 With up to Three Joinpoints,

Females by Race/Ethnicity
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

Additional information on the model used to delay-adjust SEER Incidence rates can be found at

(http://surveillance.cancer.gov/delay/).

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval.

All Races Whites Blacks

Total Males Females Total Males Females Total Males Females 

Year of Diagnosis:

1975 13.21 21.19 7.10 13.30 21.72 6.93 13.38 20.16 8.25

1976 13.28 21.01 7.38 13.23 21.03 7.37 15.18 23.76 8.37

1977 12.73 20.10 6.95 12.60 19.85 7.02 14.45 23.86 6.65

1978 13.38 20.86 7.71 13.21 20.76 7.58 15.83 25.97 8.05

1979 14.04 21.94 8.01 13.72 21.63 7.74 18.39 28.16 10.64

1980 13.34 20.26 7.91 12.98 19.98 7.60 16.82 25.39 9.59

1981 13.59 20.85 7.92 13.39 20.51 7.94 16.65 28.16 7.46

1982 13.34 20.33 7.93 13.08 19.94 7.85 17.12 27.39 8.86

1983 13.29 21.21 7.25 13.26 21.22 7.31 16.13 26.09 8.32

1984 13.47 20.78 7.86 13.00 20.15 7.64 18.92 30.01 10.08

1985 13.34 19.84 8.24 13.28 19.62 8.36 16.13 25.99 8.54

1986 12.47 19.14 7.19 12.36 18.88 7.29 16.19 28.11 6.97

1987 13.20 20.53 7.52 13.11 20.17 7.68 16.82 30.03 7.00

1988 12.13 18.16 7.31 11.79 17.71 7.09 16.45 25.58 9.09

1989 12.12 18.31 7.26 11.85 17.73 7.30 15.77 27.19 7.06

1990 12.65 19.40 7.34 12.39 18.82 7.41 16.07 27.94 6.93

1991 12.18 18.37 7.26 12.10 18.15 7.31 14.43 23.75 7.33

1992 11.96 18.32 6.92 11.83 18.04 6.94 14.82 25.12 6.95

1993 12.44 18.73 7.30 12.25 18.44 7.23 15.57 24.91 8.12

1994 11.73 17.69 6.85 11.44 16.90 6.94 15.66 26.70 7.00

1995 11.55 16.97 7.20 11.55 16.76 7.35 13.66 22.86 6.68

1996 11.79 17.79 7.00 11.49 17.30 6.88 15.06 24.51 7.65

1997 11.53 17.37 6.77 11.57 17.26 6.89 11.53 18.39 6.22

1998 11.26 16.73 6.77 11.29 16.50 6.94 13.10 22.50 6.35

1999 10.60 15.58 6.48 10.52 15.48 6.39 11.84 19.98 5.85

2000 10.76 16.07 6.30 10.71 15.69 6.45 11.74 20.80 4.89

2001 10.83 15.50 6.92 10.93 15.62 6.96 11.97 18.77 6.96

2002 11.13 16.32 6.74 11.35 16.62 6.84 11.22 17.10 6.57

2003 10.51 15.62 6.17 10.49 15.65 6.03 11.79 17.00 7.62

2004 10.81 16.08 6.25 11.05 16.43 6.29 10.21 16.46 5.65

2005 10.69 15.58 6.52 10.85 16.00 6.38 11.12 16.68 6.98

2006 10.70 15.70 6.39 10.92 15.89 6.56 9.94 16.51 5.06

2007 10.73 15.93 6.22 11.06 16.36 6.32 10.04 16.00 5.52

2008 10.97 16.27 6.39 11.42 16.87 6.60 8.99 14.11 5.15

Table 20.5

Cancer of the Oral Cavity and Pharynx (Invasive)

Delay-adjusted SEER Incidencea Rates by Year, Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks

Total Males Females Total Males Females Total Males Females 

Year of Diagnosis:

1975 13.21 21.19 7.10 13.30 21.72 6.93 13.38 20.16 8.25

1976 13.28 21.01 7.38 13.23 21.03 7.37 15.18 23.76 8.37

1977 12.73 20.10 6.95 12.60 19.85 7.02 14.45 23.86 6.65

1978 13.38 20.86 7.71 13.21 20.76 7.58 15.83 25.97 8.05

1979 14.04 21.94 8.01 13.72 21.63 7.74 18.39 28.16 10.64

1980 13.34 20.26 7.91 12.98 19.98 7.60 16.82 25.39 9.59

1981 13.59 20.85 7.92 13.39 20.51 7.94 16.65 28.16 7.46

1982 13.34 20.33 7.93 13.08 19.93 7.85 17.12 27.39 8.86

1983 13.29 21.21 7.25 13.26 21.21 7.30 16.13 26.08 8.32

1984 13.46 20.78 7.86 13.00 20.14 7.64 18.91 29.99 10.07

1985 13.33 19.84 8.24 13.27 19.61 8.35 16.12 25.98 8.53

1986 12.46 19.13 7.19 12.35 18.87 7.29 16.18 28.09 6.97

1987 13.20 20.52 7.52 13.10 20.15 7.67 16.81 30.00 6.99

1988 12.13 18.15 7.30 11.78 17.70 7.09 16.43 25.56 9.08

1989 12.12 18.30 7.26 11.84 17.71 7.30 15.75 27.16 7.05

1990 12.64 19.38 7.34 12.37 18.79 7.39 16.05 27.89 6.92

1991 12.17 18.36 7.25 12.08 18.12 7.30 14.41 23.71 7.32

1992 11.95 18.31 6.92 11.80 18.01 6.93 14.79 25.08 6.94

1993 12.43 18.71 7.29 12.23 18.41 7.21 15.54 24.85 8.10

1994 11.72 17.68 6.84 11.41 16.86 6.93 15.62 26.64 6.99

1995 11.54 16.95 7.19 11.52 16.72 7.33 13.63 22.80 6.66

1996 11.78 17.77 6.99 11.46 17.25 6.87 15.02 24.44 7.63

1997 11.51 17.35 6.76 11.53 17.20 6.86 11.49 18.32 6.20

1998 11.24 16.70 6.76 11.24 16.43 6.91 13.05 22.41 6.32

1999 10.57 15.54 6.47 10.47 15.41 6.36 11.79 19.89 5.82

2000 10.73 16.03 6.29 10.65 15.61 6.42 11.68 20.70 4.87

2001 10.80 15.45 6.90 10.87 15.54 6.92 11.90 18.67 6.92

2002 11.09 16.27 6.72 11.28 16.51 6.79 11.14 16.99 6.53

2003 10.48 15.56 6.15 10.41 15.53 5.99 11.70 16.88 7.56

2004 10.76 16.02 6.22 10.95 16.30 6.24 10.13 16.32 5.60

2005 10.64 15.51 6.49 10.75 15.85 6.32 11.01 16.53 6.91

2006 10.63 15.60 6.35 10.79 15.70 6.48 9.82 16.31 5.00

2007 10.63 15.78 6.16 10.88 16.10 6.22 9.87 15.74 5.43

2008 10.77 15.99 6.28 11.11 16.42 6.43 8.75 13.73 5.01

1975-2008 11.94 18.00 7.03 11.92 17.92 7.05 13.40 21.79 6.95

Table 20.6

Cancer of the Oral Cavity and Pharynx (Invasive)

Age-adjusted SEER Incidencea Rates by Year, Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a SEER 17 areas. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130),

unless noted.

b US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130), unless noted.

c Rates are per 100,000 and are age-adjusted to the IARC world standard population.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks

Total Males Females Total Males Females Total Males Females 

SEER Incidence

Age at Diagnosis

Age-Adjusted Rates, 2004-2008

All ages 10.6 15.7 6.2 10.8 16.1 6.2 9.9 15.6 5.6

Under 65 6.4 9.5 3.4 6.4 9.6 3.3 6.5 10.0 3.7

65 and over 39.3 58.5 25.0 40.7 60.5 26.0 33.1 54.5 18.7

All ages (IARC world std)c 7.6 11.3 4.3 7.7 11.5 4.3 7.4 11.7 4.1

Age-Specific Rates, 2004-2008

<1 - - - - - - - - -

1-4 - - - - - - - - -

5-9 0.1 - 0.1 0.1 - - - - -

10-14 0.3 0.3 0.3 0.3 0.2 0.3 0.5 - -

15-19 0.4 0.5 0.4 0.4 0.4 0.3 0.6 - -

20-24 0.8 0.7 0.9 0.7 0.7 0.8 0.8 - 1.0

25-29 1.0 1.0 1.0 0.9 0.8 0.9 1.0 1.0 0.9

30-34 1.7 1.7 1.6 1.5 1.5 1.4 1.5 1.2 1.8

35-39 3.0 3.6 2.5 2.7 3.3 2.1 2.7 3.1 2.4

40-44 5.8 8.1 3.5 5.6 8.0 3.2 5.6 7.7 3.8

45-49 11.4 17.1 5.9 11.5 17.4 5.5 11.6 15.8 7.9

50-54 19.4 29.7 9.4 19.7 30.3 9.1 21.3 33.1 11.1

55-59 26.5 41.7 12.1 27.1 42.4 12.3 27.8 47.3 11.7

60-64 32.2 50.4 15.6 33.5 52.1 16.1 30.7 51.6 14.2

65-69 37.2 56.3 20.5 38.3 57.0 21.6 37.4 64.5 16.8

70-74 39.0 58.1 23.5 40.7 59.9 24.7 36.9 63.6 17.8

75-79 40.2 58.5 26.8 41.8 60.7 27.6 33.0 48.5 23.2

80-84 41.0 60.4 28.7 42.8 63.7 29.5 25.3 42.9 15.7

85+ 40.6 62.3 30.6 41.9 65.1 31.3 24.7 37.4 19.9

U.S. Mortality

Age at Death

Age-Adjusted Rates, 2004-2008

All ages

Under 65

65 and over

All ages (IARC world std)c

Age-Specific Rates, 2004-2008

<1

1-4

5-9

10-14

15-19

20-24

25-29

30-34

35-39

40-44

45-49

50-54

55-59

60-64

65-69

70-74

75-79

80-84

85+

Table 20.8

Cancer of the Oral Cavity and Pharynx (Invasive)

SEER Incidencea and U.S. Deathb Rates, Age-Adjusted and Age-Specific Rates, by Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a SEER 17 areas. Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130),

unless noted.

b US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130), unless noted.

c Stage distribution was not calculated for this site due to inconsistent coding of stage over time.

d Percents may not sum to 100 due to rounding.

e Rates are per 100,000 and are age-adjusted to the IARC world standard population.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

Site

Oral Gum & Oropharynx Other Oral

Cavity & Floor of Other & Salivary Cavity &

Pharynx Lip Tongue Mouth Mouthc Tonsilc Hypophar.c Gland Nasophar.c Pharynxc

SEER Incidence

Stage Distribution, 2004-2008

Percent of Totald

Localized 33 87 35 40 - - - 43 - -

Regional 44 4 44 48 - - - 33 - -

Distant 17 2 16 6 - - - 16 - -

Unstaged 7 7 5 6 - - - 7 - -

Age-Adjusted Rates, 2004-2008

Age at Diagnosis

All ages 10.6 0.7 3.0 0.6 1.5 2.0 0.7 1.3 0.7 0.2

Under 65 6.4 0.3 1.9 0.3 0.7 1.5 0.3 0.7 0.5 0.1

65+ 39.3 3.6 10.6 2.3 7.0 5.0 2.9 5.4 1.6 0.9

All ages(IARC world std)e 7.6 0.4 2.2 0.4 1.0 1.5 0.5 0.9 0.5 0.1

Sex

Male 15.7 1.2 4.5 0.9 1.8 3.3 1.1 1.7 1.0 0.3

Female 6.2 0.3 1.7 0.3 1.2 0.8 0.2 1.0 0.4 0.1

Race

White 10.8 0.8 3.2 0.6 1.5 2.1 0.6 1.3 0.4 0.2

Black 9.9 0.1 2.3 0.6 1.5 2.3 1.1 1.0 0.7 0.3

Other 9.0 0.4 2.1 0.3 1.4 0.8 0.4 1.1 2.4 0.1

U.S. Mortality

Age-Adjusted Rates, 2004-2008

Age at Death

All ages

Under 65

65+

All ages(IARC world std)e

Sex

Male

Female

Race

White

Black

Other

Table 20.9

Cancer of the Oral Cavity and Pharynx by Subsite (Invasive)

SEER Incidencea Stage Distribution by Site,

Age-Adjusted SEER Incidencea and U.S. Deathb Rates by Age, Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registry.

b SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).

Based on follow-up of patients into 2008.

c SEER 17 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,

Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana and New Jersey).

Based on follow-up of patients into 2008.

d Period survival provides a 2007 estimate of survival by piecing together the most recent conditional survival estimates

from several cohorts. It is computed here using three year calendar blocks (2005-2007: 0-1 year survival),

(2004-2006: 1-2 year survival), (2003-2005: 2-3 year survival), (2002-2004: 3-4 year survival), (2001-2003: 4-5 years survival).

e The difference between 1975-1977 and 2001-2007 is statistically significant (p<.05).

f The standard error is between 5 and 10 percentage points.

g The standard error is greater than 10 percentage points.

- Statistic could not be calculated due to fewer than 25 cases during the time period.

All Races Whites Blacks

Total Males Females Total Males Females Total Males Females 

5-Year Relative Survival (Percent)

Year of Diagnosis:

1960-1963a - - - 45 - - - - -

1970-1973a - - - 43 - - - - -

1975-1977b 52.9 51.9 55.2 54.4 54.0 55.1 36.1 29.8 49.0

1978-1980b 53.5 52.0 56.7 55.5 54.6 57.5 34.9 30.0 45.8

1981-1983b 51.9 50.4 55.2 54.2 53.1 56.6 31.4 26.0 45.9

1984-1986b 54.2 51.8 59.1 56.4 54.9 59.4 35.1 29.5 49.4

1987-1989b 53.8 51.2 59.4 56.3 54.2 60.4 33.9 29.8 44.2

1990-1992b 55.5 53.3 60.2 58.1 56.5 61.2 32.5 27.8 45.7

1993-1995b 57.8 56.4 60.7 60.3 59.7 61.4 38.0 33.1 50.7

1996-2000b 58.9 57.5 61.9 60.9 60.4 62.0 39.8 34.5 53.8

2001-2007b 63.2e 62.7e 64.2e 65.1e 65.2e 64.9e 44.7e 40.5e 53.4

5-Year Period Survival (Percent)cd

2007 61.5 60.8 63.1 63.2 63.0 63.7 41.7 36.8 52.0

Stage Distribution (%) 2001-2007c

All Stages

Number of cases 43,977 30,455 13,522 35,891 25,082 10,809 4,148 2,874 1,274

Percent 100% 100% 100% 100% 100% 100% 100% 100% 100%

Localized 33 29 42 34 30 43 21 17 32

Regional 46 49 38 46 50 37 50 53 42

Distant 15 16 13 14 15 12 23 25 19

Unstaged 6 6 7 6 6 7 6 5 6

5-Year Relative Survival (Percent), 2001-2007c

Age at Diagnosis:

Ages <45 78.0 74.5 84.0 79.8 77.0 85.0 62.7 52.7 76.3

Ages 45-54 66.1 64.7 70.6 69.5 68.3 73.7 40.8 37.9 47.5

Ages 55-64 61.0 59.7 65.4 63.1 61.9 66.9 38.8 36.8 45.9

Ages 65-74 55.2 54.3 57.2 57.0 57.0 57.1 35.1 28.9 50.5

Ages 75+ 47.7 46.8 48.7 48.9 48.1 49.7 35.3 30.0 39.9

Ages <65 66.1 64.0 72.1 68.3 66.6 73.6 44.5 39.9 55.7

Ages 65+ 51.7 51.3 52.3 53.1 53.3 52.8 35.3 29.2 45.7

Stage:

All Stages 60.8 59.8 62.9 62.4 62.0 63.2 42.1 37.3 52.6

Localized 82.3 81.8 83.2 82.6 82.4 82.8 75.0 67.8 82.5

Regional 55.6 56.7 52.2 57.5 59.2 52.2 37.2 35.5 41.7

Distant 33.5 33.1 34.4 33.5 33.6 33.2 22.7 20.2 29.9

Unstaged 50.4 49.3 52.5 50.2 49.1 52.4 38.4 36.4 42.3f

Table 20.10

Cancer of the Oral Cavity and Pharynx (Invasive)

5-Year Relative and Period Survival (Percent) by Race, Sex, Diagnosis Year, Stage and Age
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a SEER 17 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,

Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana and New Jersey).

Based on follow-up of patients into 2008.

b The standard error is between 5 and 10 percentage points.

c The standard error is greater than 10 percentage points.

d Survival by stage was not calculated for this site due to inconsistent coding of stage over time.

- Statistic could not be calculated due to fewer than 25 cases during the time period.

Case Survival Time

Number Distribution 1-Year 2-Year 3-Year 4-Year 5-Year

Site of Cases (%) Percent Percent Percent Percent Percent

Oral Cavity & Pharynx 43977 100 83.0 72.5 67.1 63.4 60.8

Lip 3258 7 98.7 96.0 94.3 91.8 90.5

Tongue 12112 28 82.7 70.4 64.8 61.4 59.4

Gum & Other Mouth 5875 13 81.1 70.9 65.4 61.9 58.1

Floor of Mouth 2571 6 79.9 67.3 59.3 54.8 51.2

Oropharynx & Tonsil 8509 19 83.8 74.1 69.4 65.6 62.9

Hypopharynx 2679 6 66.0 48.2 39.3 34.6 30.2

Salivary Gland 5088 12 88.9 81.1 76.3 73.2 71.3

Nasopharynx 3116 7 82.9 73.2 66.6 61.8 58.3

Other Oral Cavity & Pharynx 769 2 59.0 46.9 41.0 37.8 35.8

5-Year Relative Survival (Percent), 2001-2007

Stage All Stages

White White Black Black

SITE All Stages Localized Regional Distant Unstaged Male Female Male Female

Oral Cavity & Pharynx 60.8 82.3 55.6 33.5 50.4 62.0 63.2 37.3 52.6

Lip 90.5 93.6 56.6b 37.3c 79.7 90.7 89.7 - -

Tongue 59.4 77.2 56.1 30.6 51.8 61.8 60.3 30.5 38.1

Gum & Other Mouthd 58.1 - - - - 56.7 61.6 41.4 64.1

Floor of Mouth 51.2 73.7 37.0 19.8 41.2b 50.3 58.0 36.0 51.3b

Oropharynx & Tonsild 62.9 - - - - 67.3 60.6 38.0 38.6

Hypopharynxd 30.2 - - - - 32.7 32.1 19.2 21.8b

Salivary Gland 71.3 92.9 59.7 36.8 53.1 63.3 78.9 66.7 78.1

Nasopharynxd 58.3 - - - - 53.3 49.4 50.0 62.3b

Other Oral Cavity & Pharynxd 35.8 - - - - 42.5 27.5 23.1b 15.3b

Table 20.11

Cancer of the Oral Cavity and Pharynx by Subsite (Invasive)

SEERa Relative Survival (Percent) by Cancer Site, 2001-2007
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a Based on the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

1975- 1980- 1985-

1979 1984 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 

Survival Time

1-year 80.3 80.0 81.3 82.0 81.8 80.3 82.0 83.7 83.4 82.2 84.2 81.5 84.1 85.3 83.3 84.2 84.4 84.8 83.8 85.6 85.1

2-year 66.3 66.3 68.0 69.9 69.5 69.0 68.8 72.1 71.9 70.3 71.4 70.4 72.6 73.7 73.3 73.2 75.0 75.5 74.3 75.4

3-year 60.0 59.8 61.3 63.2 62.9 61.7 62.8 66.4 65.6 63.8 66.2 64.5 65.6 68.7 67.4 67.7 70.1 70.6 68.6

4-year 56.0 55.7 57.4 59.9 58.2 57.0 58.6 62.1 61.8 60.1 62.2 60.2 62.0 64.9 62.8 64.3 67.3 66.5

5-year 53.0 52.5 54.2 57.0 54.8 54.7 55.7 59.2 58.7 57.9 58.6 57.1 58.9 62.0 60.1 62.1 65.0

6-year 50.6 49.8 51.7 54.9 52.1 52.2 53.4 56.3 56.1 55.4 56.1 55.8 56.1 60.1 58.2 59.8

7-year 48.5 47.6 49.1 52.6 50.0 49.4 50.9 55.1 53.5 53.6 54.4 53.8 53.7 58.0 56.3

8-year 46.3 46.0 47.0 50.9 48.6 47.2 48.8 51.9 51.3 51.2 53.1 52.7 51.9 55.6

9-year 44.4 44.1 45.1 48.3 47.0 45.2 46.5 49.3 49.3 49.8 51.7 52.1 50.1

10-year 42.4 42.4 43.4 46.5 45.2 43.7 45.0 47.0 47.7 47.6 49.9 50.9

11-year 40.6 40.8 42.1 45.3 43.0 41.5 43.3 45.2 45.8 46.3 47.8

12-year 39.1 39.4 40.6 44.3 40.8 40.3 42.5 44.0 44.0 45.4

13-year 37.9 37.6 39.1 42.3 39.9 38.7 41.1 42.2 42.6

14-year 36.8 36.6 37.8 41.0 38.9 37.3 40.0 40.3

15-year 35.3 35.0 36.7 40.3 37.9 36.0 39.1

16-year 34.0 33.9 35.6 39.8 36.0 35.3

17-year 33.1 32.9 34.6 38.9 34.4

18-year 32.0 31.9 33.2 38.0

19-year 31.3 30.3 31.9

20-year 30.1 29.8

Table 20.12

Cancer of the Oral Cavity and Pharynx (Invasive)

SEERa Relative Survival (Percent)

By Year of Diagnosis

All Races, Males and Females

Year of Diagnosis
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a Based on the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

1975- 1980- 1985-

1979 1984 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 

Survival Time

Cancer of the Tongue

1-year 75.3 74.3 77.7 80.3 82.2 77.1 81.8 82.0 80.1 80.0 82.4 80.2 82.0 85.4 82.2 82.0 85.2 87.3 85.1 84.7 86.2

2-year 55.3 57.8 60.7 64.3 67.2 60.2 65.4 68.5 65.6 67.2 71.1 66.2 68.2 71.8 71.1 69.5 71.7 75.8 72.6 73.9

3-year 47.7 51.0 54.7 58.1 59.1 50.6 57.0 62.9 58.7 61.2 65.1 59.3 60.1 66.5 64.6 64.0 67.1 71.0 65.2

4-year 43.7 47.5 50.2 55.4 53.7 46.6 54.0 58.4 56.5 57.3 61.9 55.6 57.8 63.6 61.2 61.6 64.9 66.5

5-year 40.3 44.8 47.5 52.4 52.8 43.7 51.6 54.4 54.2 55.5 57.9 52.9 54.8 62.1 58.5 59.9 62.0

6-year 38.4 41.9 45.3 50.3 49.2 42.2 49.5 52.0 50.6 53.0 56.2 52.4 52.8 60.4 57.2 57.3

7-year 37.2 39.3 42.5 47.7 47.4 40.3 46.7 51.2 48.6 51.7 55.3 49.4 50.4 58.4 54.5

8-year 35.7 37.5 40.6 45.6 46.7 38.8 44.4 47.5 46.5 49.9 53.8 47.9 50.4 56.1

9-year 34.4 34.8 38.9 42.6 45.0 35.0 41.9 45.4 44.8 48.6 52.8 47.2 48.6

10-year 32.6 33.4 37.7 40.7 42.3 32.6 41.3 43.8 43.5 46.5 52.3 45.7

Cancer of the Lip

1-year 99.4 98.1 99.6 98.9 100.0 100.0 99.3 100.0 99.9 98.5 100.0 99.5 97.6 98.0 95.0 99.6 99.4 99.6 98.1 96.7 95.8

2-year 97.6 96.2 98.2 97.7 98.3 98.3 98.4 100.0 99.7 94.3 97.3 98.3 95.4 96.0 94.0 99.6 99.4 99.6 95.5 93.8

3-year 97.3 93.8 97.3 96.2 98.3 96.4 98.2 100.0 99.1 92.7 95.4 96.2 93.9 95.2 94.0 97.5 97.6 98.4 95.1

4-year 96.0 92.4 97.1 96.2 97.7 94.5 98.2 98.8 96.4 91.3 93.9 94.2 92.1 92.5 91.4 97.5 97.6 95.5

5-year 94.7 90.1 96.2 94.8 95.4 93.8 96.1 98.4 95.4 88.6 91.4 91.8 90.5 90.0 90.5 94.8 97.6

6-year 92.8 88.0 95.4 92.8 95.4 90.3 95.6 98.1 95.4 87.4 89.7 90.3 89.4 90.0 87.6 93.0

7-year 91.5 86.6 93.5 92.1 95.4 87.2 94.0 98.0 95.4 86.4 88.7 90.1 88.9 89.9 84.8

8-year 90.1 86.2 92.1 92.0 95.4 84.5 91.2 96.7 91.5 83.1 88.7 87.3 88.9 89.9

9-year 88.0 85.3 91.4 89.9 94.8 83.1 89.9 94.6 86.7 82.7 88.7 87.2 88.3

10-year 86.0 83.9 91.3 89.3 92.9 81.0 87.7 91.0 82.1 82.7 86.2 86.7

Cancer of the Oropharynx and Tonsil

1-year 71.3 72.3 73.9 76.8 76.6 71.4 77.5 74.5 81.0 80.4 81.8 81.5 87.4 82.8 84.0 85.7 82.7 84.3 84.3 85.5 86.6

2-year 54.0 53.1 56.6 60.4 62.5 58.3 64.5 63.4 70.0 66.7 67.0 66.7 75.3 67.5 72.4 76.5 75.8 74.8 74.2 75.6

3-year 44.5 44.7 46.1 51.5 56.9 49.5 55.3 57.2 62.6 60.2 61.8 59.8 67.6 62.2 67.1 71.7 71.3 71.2 70.5

4-year 39.0 39.5 41.7 47.6 52.2 44.6 49.3 52.7 58.3 53.8 56.2 54.6 63.1 57.3 60.8 67.5 68.4 67.0

5-year 35.8 35.4 38.0 42.9 45.5 41.0 45.7 49.3 54.0 52.5 51.5 52.7 60.4 53.4 59.1 64.4 64.9

6-year 32.2 32.2 34.8 42.6 40.5 39.8 43.6 46.1 50.2 47.8 48.2 51.0 57.2 52.2 55.0 63.4

7-year 30.3 29.6 32.1 40.5 38.8 38.3 42.5 45.3 46.5 43.5 47.2 49.5 55.1 48.4 53.1

8-year 26.6 28.0 30.4 39.1 36.0 37.0 40.4 41.7 45.3 42.0 46.2 48.7 51.5 46.4

9-year 23.8 25.7 28.4 35.4 33.9 35.2 37.6 40.3 43.9 41.0 44.2 48.4 51.3

10-year 22.5 23.2 26.3 35.2 32.0 35.2 34.2 39.3 42.6 39.8 43.1 45.9

Table 20.13

Cancer of the Oral Cavity and Pharynx For Selected Subsites (Invasive)

SEERa Relative Survival (Percent)

By Year of Diagnosis

All Races, Males and Females

Year of Diagnosis
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a Based on the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

1975- 1980- 1985-

1979 1984 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 

Survival Time

1-year 79.7 79.5 80.5 81.2 81.4 79.6 80.9 83.8 83.3 82.0 83.4 81.1 84.5 85.1 83.9 84.4 84.8 85.4 84.4 85.6 86.2

2-year 65.5 65.4 66.5 67.8 68.5 67.7 67.3 72.3 71.1 69.7 69.9 70.3 71.6 73.2 73.4 72.0 74.8 75.4 74.7 74.9

3-year 59.2 58.4 59.2 61.3 61.2 59.7 60.5 65.2 65.1 62.8 64.7 63.9 64.1 67.6 67.8 65.6 69.7 69.8 68.4

4-year 54.8 54.2 55.1 57.8 55.2 55.5 56.7 60.6 60.8 58.8 60.0 59.3 60.3 64.0 62.5 62.4 66.8 65.4

5-year 51.8 50.9 51.6 54.9 51.7 53.2 53.7 58.0 57.8 56.6 56.4 56.1 57.4 60.9 59.8 60.5 64.9

6-year 49.5 48.2 49.4 52.7 49.2 50.9 51.1 55.5 55.0 53.6 53.9 54.8 54.4 58.6 57.5 58.3

7-year 47.3 46.0 47.1 50.3 46.9 47.8 48.2 54.4 52.0 51.3 52.6 52.6 52.4 56.3 55.5

8-year 45.3 44.4 44.8 49.0 45.6 45.6 46.9 51.4 49.7 49.1 51.4 51.2 50.8 53.7

9-year 43.3 42.7 42.9 46.4 44.1 43.6 44.4 48.7 47.6 48.0 49.8 50.4 49.3

10-year 41.2 40.7 40.9 45.3 42.0 42.1 43.2 46.5 45.8 45.8 48.2 49.2

11-year 39.4 39.2 39.7 44.1 40.1 40.3 41.6 45.0 43.8 44.1 46.3

12-year 38.0 37.8 38.3 43.3 37.6 39.0 40.6 43.8 42.0 43.2

13-year 36.9 36.4 36.9 41.3 36.9 37.5 38.7 42.1 40.4

14-year 35.9 35.4 35.7 39.8 36.3 36.0 37.8 39.8

15-year 34.5 34.0 34.7 39.0 35.5 34.5 37.2

16-year 33.1 32.8 33.7 38.2 33.0 33.9

17-year 32.2 31.8 32.7 37.4 31.8

18-year 31.2 30.7 31.5 36.2

19-year 30.6 28.9 30.0

20-year 29.5 28.3

Table 20.14

Cancer of the Oral Cavity and Pharynx (Invasive)

SEERa Relative Survival (Percent)

By Year of Diagnosis

All Races, Males

Year of Diagnosis
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a Based on the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

1975- 1980- 1985-

1979 1984 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 

Survival Time

1-year 81.6 81.2 82.7 83.8 82.7 81.8 84.3 83.3 83.4 82.5 86.1 82.3 83.3 85.7 82.3 83.7 83.6 83.3 82.7 85.6 82.4

2-year 68.2 68.1 70.9 74.3 71.3 71.8 72.2 71.6 73.4 71.4 74.6 70.5 74.5 74.8 73.0 75.7 75.4 75.7 73.5 76.6

3-year 61.8 62.7 65.5 67.3 66.3 65.7 67.7 68.8 66.6 66.0 69.5 65.7 68.7 71.2 66.6 72.1 70.9 72.4 69.0

4-year 58.8 58.7 62.1 64.4 64.1 60.2 62.8 65.2 63.6 62.7 66.9 62.1 65.8 67.0 63.2 68.4 68.3 69.2

5-year 55.8 56.0 59.6 61.7 61.0 58.0 59.7 61.7 60.4 60.5 63.5 59.2 62.1 64.3 60.8 65.3 65.2

6-year 53.2 53.2 56.4 59.7 58.0 54.8 58.3 58.1 58.3 59.0 60.9 57.7 59.6 63.3 59.6 63.0

7-year 51.2 50.9 53.2 57.5 56.4 52.8 56.6 56.5 56.3 58.3 58.5 56.4 56.3 61.7 58.0

8-year 48.7 49.3 51.6 55.1 54.5 50.7 52.8 52.8 54.4 55.5 56.9 55.8 54.1 59.9

9-year 47.0 47.1 49.7 52.4 52.7 48.5 50.8 50.5 52.4 53.3 55.9 55.8 51.9

10-year 45.1 45.7 48.5 49.0 51.5 47.0 48.9 48.3 51.0 51.4 53.5 54.5

11-year 43.1 44.3 47.0 47.8 48.7 43.9 46.9 45.5 49.4 50.9 51.0

12-year 41.6 42.6 45.2 46.4 47.2 42.6 46.5 44.7 47.5 49.7

13-year 40.1 40.3 43.5 44.6 45.6 41.4 46.0 42.5 46.6

14-year 38.8 39.3 42.0 43.5 44.0 39.9 44.7 41.3

15-year 37.2 37.3 40.8 43.0 42.9 38.9 43.1

16-year 36.1 36.2 39.4 43.0 41.8 38.2

17-year 35.2 35.2 38.6 42.2 39.6

18-year 33.9 34.3 36.8 41.7

19-year 32.8 33.2 35.9

20-year 31.5 32.7

Table 20.15

Cancer of the Oral Cavity and Pharynx (Invasive)

SEERa Relative Survival (Percent)

By Year of Diagnosis

All Races, Females

Year of Diagnosis
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval. The AAPCs are calculated by

the Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

Trend based on less than 10 cases for at least one year within the time interval.

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). Trends

are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah

and Atlanta.

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey, Los Angeles, the Alaska

Native Registry and Rural Georgia.

The SEER 17 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky,

Louisiana and New Jersey.

c The 1999-2008 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints over

diagnosis years 1992-2008.

d The 1999-2008 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints over

diagnosis years 1975-2008.

e Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific

Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics

are based on NHIA and exclude cases from the Alaska Native Registry. The 2004-2008 Hispanic and

Non-Hispanic death rates exclude deaths from the District of Columbia, New Hampshire, and North

Dakota. The 1999-2008 Hispanic and Non-Hispanic mortality trends exclude deaths from

Connecticut, the District of Columbia, Maine, Maryland, Minnesota, New Hampshire, New York, North

Dakota, Oklahoma and Vermont.

f Incidence data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service

Delivery Area) counties.

g US Mortality Files, National Center for Health Statistics, CDC.

h The 1999-2008 mortality AAPCs are based on a Joinpoint analysis using years of death 1992-2008.

* The APC is significantly different from zero (p<.05).

SEER Incidence SEER 17 Areasb SEER 13 Areasb SEER 9 Areasb

Rate 2004-2008 Trend 1999-2008c Trend 1999-2008d

Rate per 100,000 persons AAPC (%) AAPC (%)

Total Males Females Total Males Females Total Males Females

RACE/ETHNICITY

All Races 10.6 15.7 6.2 -1.0* -0.4 -1.0* -1.0* -0.4 -0.9*

White 10.8 16.1 6.2 -0.8* -0.1 -1.1* 0.0 -0.1 -0.9*

White Hispanice 5.7 8.3 3.5 -1.9* -2.3* -1.4* - - -

White Non-Hispanice 11.7 17.5 6.7 -0.5* 0.1 -0.9* - - -

Black 9.9 15.6 5.6 -2.8* -3.2* -1.6* -2.6* -3.2* -1.5*

Asian/Pacific Islander 7.9 10.9 5.3 -0.9* -1.0* -0.5 - - -

Amer Ind/Alaska Natf 7.0 9.1 5.1 -3.5* - - - - -

Hispanice 5.6 8.2 3.4 -1.8* -2.1* -1.4* - - -

U.S. Mortalityg

Rate 2004-2008 Trend 1999-2008h

Rate per 100,000 persons AAPC (%)

Total Males Females Total Males Females

RACE/ETHNICITY

All Races

White

White Hispanice

White Non-Hispanice

Black

Asian/Pacific Islander

Amer Ind/Alaska Nat

Total U.S.

CHSDA Counties

Non-CHSDA Counties

Hispanice

Table 20.19

Cancer of the Oral Cavity and Pharynx (Invasive)

SEER Incidence and U.S. Mortality

Age-Adjusted Rates and Trendsa

By Race/Ethnicity and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

The APC is the Annual Percent Change over the time interval.

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

Trends are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

b Incidence data used in calculating the rates are from the 17 SEER areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa,

New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia,

California excluding SF/SJM/LA, Kentucky, Louisiana and New Jersey).

c Incidence data used in calculating the trends are from the 13 SEER areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa,

New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry and Rural Georgia).

- Statistic not shown. Rate based on less than 16 cases for the time interval. Trend based on less than 10 cases for at least

one year within the time interval.

* The APC is significantly different from zero (p<.05).

Site

Oral Gum & Oropharynx Other Oral

Cavity & Floor of Other & Salivary Cavity &

Pharynx Lip Tongue Mouth Mouth Tonsil Hypophar. Gland Nasophar. Pharynx

2004-2008, Rate per 100,000 personsb

All Races

Male and Female 10.6 0.7 3.0 0.6 1.5 2.0 0.7 1.3 0.7 0.2

Male 15.7 1.2 4.5 0.9 1.8 3.3 1.1 1.7 1.0 0.3

Female 6.2 0.3 1.7 0.3 1.2 0.8 0.2 1.0 0.4 0.1

White

Male and Female 10.8 0.8 3.2 0.6 1.5 2.1 0.6 1.3 0.4 0.2

Male 16.1 1.4 4.7 0.9 1.8 3.5 1.1 1.8 0.6 0.3

Female 6.2 0.4 1.8 0.3 1.2 0.8 0.3 1.0 0.3 0.1

Black

Male and Female 9.9 0.1 2.3 0.6 1.5 2.3 1.1 1.0 0.7 0.3

Male 15.6 0.1 3.7 1.0 1.9 4.2 2.1 1.0 1.2 0.5

Female 5.6 - 1.2 0.3 1.3 0.8 0.3 1.0 0.3 0.2

Trend 1999-2008c ,APC(%)

All Races

Male and Female -0.4 -6.3* 1.7* -4.2* -1.9* 2.5* -3.4* 0.7 0.5 -5.3*

Male -0.4 -6.8* 2.1* -4.6* -2.3* 2.8* -3.0* 0.6 0.3 -5.0*

Female -0.6 -4.6* 1.0 -3.7* -1.4 0.6 -4.5* 0.6 0.7 -5.9*

White

Male and Female -0.1 -6.0* 2.3* -3.6* -1.9* 3.1* -3.0* 0.5 1.1 -5.6*

Male -0.1 -6.6* 2.4* -4.1* -2.0* 3.5* -2.8* 0.6 0.6 -4.6*

Female -0.5 -4.2* 2.0* -3.3* -1.8* 0.8 -4.0 0.0 2.0 -

Black

Male and Female -2.8* - -3.0* -8.7* -4.1 0.2 -2.5 -0.7 -1.6 -

Male -3.3* - -2.9* -10.3* -6.7* 0.2 -1.5 -4.3* -1.8 -

Female -1.4 - -2.8 - -0.7 0.0 - 2.3 - -

Table 20.20

Cancer of the Oral Cavity and Pharynx by Subsite (Invasive)

SEER Incidence

Age-Adjusted Rates and Trendsa by Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah and Atlanta.

The SEER 11 areas comprise the SEER 9 areas plus San Jose-Monterey and Los Angeles.

The SEER 13 areas comprise the SEER 11 areas plus the Alaska Native Registry and Rural Georgia.

The SEER 17 areas comprise the SEER 13 areas plus California excluding SF/SJM/LA, Kentucky, Louisiana and New Jersey.

- Statistic not shown. Rate based on less than 16 cases for the time interval.

All Races Whites Blacks

Total Males Females Total Males Females Total Males Females 

SEER Incidence Ratesa, 2004-2008

Atlanta & Rural Georgia 9.45 14.56 5.25 10.07 15.21 5.51 8.27 13.83 4.52

Atlanta 9.34 14.49 5.15 9.87 14.99 5.36 8.42 14.33 4.49

Rural Georgia 10.98 15.86 6.57 13.49 18.77 8.20 6.21 - -

California 10.23 15.05 6.12 10.53 15.63 6.09 9.34 13.72 5.82

Greater Bay Area 10.55 15.01 6.65 11.04 15.94 6.66 8.79 12.44 5.86

San Francisco-Oakland 10.97 15.53 7.03 11.60 16.59 7.11 8.77 12.34 6.06

San Jose-Monterey 9.72 14.01 5.92 10.07 14.81 5.88 9.18 12.81 -

Los Angeles 8.78 12.87 5.45 8.74 12.88 5.29 9.93 15.10 6.15

Greater California 10.80 16.07 6.24 11.08 16.63 6.24 9.15 13.06 5.58

Connecticut 10.70 16.11 6.12 10.52 15.72 6.08 12.46 20.96 6.23

Detroit 11.74 17.60 7.00 11.78 17.49 7.02 11.95 18.71 7.05

Hawaii 12.11 17.52 7.20 17.88 25.60 9.73 - - -

Iowa 11.40 17.39 6.27 11.18 17.05 6.15 11.49 19.20 -

Kentucky 12.33 19.15 6.59 12.29 19.11 6.50 11.43 17.44 6.76

Louisiana 12.28 19.52 6.18 12.70 19.98 6.30 11.19 18.53 5.66

New Jersey 9.93 14.67 5.97 10.05 14.71 6.11 9.10 15.07 4.85

New Mexico 9.29 13.70 5.35 9.70 14.41 5.46 - - -

Seattle-Puget Sound 11.32 16.35 6.81 11.73 16.85 7.07 7.15 11.01 -

Utah 7.65 10.78 4.76 7.72 10.87 4.79 - - -

9 SEER Areasb 10.69 15.78 6.30 10.90 16.08 6.34 9.90 15.70 5.59

11 SEER Areasb 10.21 15.04 6.09 10.41 15.34 6.10 9.87 15.46 5.70

13 SEER Areasb 10.22 15.05 6.10 10.42 15.35 6.11 9.83 15.36 5.69

17 SEER Areasb 10.56 15.72 6.15 10.77 16.06 6.17 9.90 15.59 5.57

Table 20.22

Cancer of the Oral Cavity and Pharynx (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry, Race and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

a US 2008 cancer prevalence counts are based on 2008 cancer prevalence proportions from the SEER registries and 1/1/2008

US population estimates based on the average of 2007 and 2008 population estimates from the US Bureau of the Census.

Prevalence was calculated using the First Malignant Primary Only for a person.

b c d Statistics based on (b) SEER 9 Areas (c) SEER 11 Areas and Rural Georgia (d) NHIA for Hispanic for SEER 11 Areas and

Rural Georgia.

e Maximum limited-duration prevalence: 33 years for 1975-2008 SEER 9 data; 18 years for 1990-2008 SEER 11 data

(used to calculate prevalence for Hispanics and Asian Pacific Islanders).

f Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groups.

g h i (g) Cases diagnosed more than 33 years ago were estimated using the completeness index method (Capocaccia et. al. 1997,

Merrill et. al. 2000). (h) Complete prevalence is obtained by summing 0 to <33 and >=33. (i) Age-specific completeness index

was approximated using empirical data from historical Connecticut tumor registry.

- Statistic not shown. Statistic based on fewer than 5 cases estimated alive in SEER for the time interval.

+ Not available.

Years Since Diagnosis 0 to <5 5 to <10 10 to <15 15 to <20 20 to <25 25 to <30 0 to <18e 0 to <33e >=33g Completeh

Race Sex 

All Racesb Both Sexes 91,329 55,615 36,520 23,518 15,736 10,003 202,684 240,722 12,443 253,165

Males 62,730 36,405 23,300 14,212 9,267 5,866 134,834 156,987 7,172 164,159

Females 28,599 19,210 13,220 9,306 6,469 4,137 67,850 83,735 5,271 89,006

Whiteb Both Sexes 78,234 48,573 31,799 21,004 14,028 8,815 175,746 209,525 10,587 220,112

Males 54,395 32,127 20,614 12,905 8,482 5,352 118,404 138,541 6,142 144,683

Females 23,839 16,446 11,185 8,099 5,546 3,463 57,342 70,984 4,445 75,429

Blackb Both Sexes 7,522 3,959 2,683 1,322 1,047 658 15,113 17,506 620 18,126

Males 4,854 2,365 1,467 660 450 227 9,101 10,123 237 10,360

Females 2,668 1,594 1,216 662 597 431 6,012 7,383 383 7,766

Asian/ Both Sexes 3,429 2,080 1,505 + + + 7,516 + + +

Pacific Males 2,163 1,239 896 + + + 4,607 + + +

Islanderc Females 1,266 841 609 + + + 2,909 + + +

Hispanicd Both Sexes 4,024 2,243 1,980 + + + 8,247 + + +

Males 2,546 1,418 1,068 + + + 5,032 + + +

Females 1,478 825 912 + + + 3,215 + + +

Age Specific (Crude) Age-Adjustedf

Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex 

All Racesc Both Sexes 0.0571% 0.0004% 0.0019% 0.0056% 0.0147% 0.0437% 0.1162% 0.1948% 0.2169% 0.2043% 0.0566%

Males 0.0765% 0.0003% 0.0018% 0.0056% 0.0141% 0.0573% 0.1712% 0.2958% 0.3169% 0.3071% 0.0813%

Females 0.0380% 0.0005% 0.0020% 0.0056% 0.0153% 0.0301% 0.0636% 0.1033% 0.1380% 0.1475% 0.0357%

Whitec Both Sexes 0.0608% 0.0005% 0.0017% 0.0053% 0.0133% 0.0414% 0.1189% 0.2035% 0.2305% 0.2139% 0.0580%

Males 0.0823% 0.0004% 0.0012% 0.0050% 0.0131% 0.0555% 0.1773% 0.3081% 0.3386% 0.3236% 0.0840%

Females 0.0392% 0.0005% 0.0022% 0.0058% 0.0134% 0.0268% 0.0611% 0.1060% 0.1433% 0.1535% 0.0353%

Blackc Both Sexes 0.0366% 0.0007% 0.0029% 0.0054% 0.0121% 0.0364% 0.0970% 0.1570% 0.1496% 0.1227% 0.0438%

Males 0.0470% - 0.0039% 0.0076% 0.0087% 0.0418% 0.1396% 0.2499% 0.2257% 0.1631% 0.0616%

Females 0.0272% - 0.0019% 0.0033% 0.0150% 0.0317% 0.0616% 0.0854% 0.0974% 0.1039% 0.0303%

Asian/ Both Sexes 0.0517% - 0.0017% 0.0072% 0.0224% 0.0605% 0.1081% 0.1509% 0.1654% 0.1579% 0.0519%

Pacific Males 0.0653% - 0.0025% 0.0071% 0.0232% 0.0778% 0.1466% 0.2244% 0.2148% 0.2356% 0.0698%

Islanderc Females 0.0389% - - 0.0073% 0.0217% 0.0446% 0.0746% 0.0883% 0.1285% 0.1091% 0.0372%

Hispanicd Both Sexes 0.0180% 0.0004% 0.0011% 0.0026% 0.0077% 0.0201% 0.0526% 0.1003% 0.1283% 0.1359% 0.0303%

Males 0.0212% - 0.0008% 0.0024% 0.0064% 0.0240% 0.0695% 0.1431% 0.1864% 0.1836% 0.0408%

Females 0.0147% - 0.0013% 0.0029% 0.0093% 0.0158% 0.0364% 0.0635% 0.0851% 0.1081% 0.0219%

Table 20.27

Cancer of the Oral Cavity and Pharynx (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1, 2008

By Race/Ethnicity, Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1, 2008, of the SEER 11 population diagnosed in the previous 18 years

By Age at Prevalence, Race/Ethnicity and Sex
SEER Cancer Statistics Review 1975-2008 National Cancer Institute

Source: SEER 17 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,

Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana and New Jersey).

Percents may not sum to 100 due to rounding.

a Excludes Kaposi Sarcoma, mesothelioma, lymphomas, leukemias, myelomas, lymphoreticular, and immunoproliferative diseases.

b Epidermoid carcinoma includes squamous, basal, and transitional cell carcinomas.

c Adenocarcinoma includes histologies 8050, 8140-8147, 8160-8162, 8180-8221, 8250-8507, 8514, 8520-8551, 8560, 8570-8574,

8576, 8940-8941.

d Other specific carcinomas includes histologies 8012-8015, 8030-8046, 8150-8155, 8170-8180, 8230-8249, 8508, 8510-8513,

8561-8562, 8575, 8580-8671

e Sarcoma and soft tissue includes histologies 8680-8713, 8800-8921, 8990-8991, 9040-9044, 9120-9136, 9150-9252, 9370-9373,

9540-9582.

f Other specific types includes histologies 8720-8790, 8930-8936, 8950-8983, 9060-9110, 9260-9365, 9380-9539.

- Statistic not shown due to fewer than 16 cases during the time period.

Oral Cavity

and Pharynx Lip Tongue Salivary Gland Floor of Mouth

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent 

Epidermoid carcinomab (8051-8131) 33,054 82.8% 2,522 95.0% 11,107 96.7% 1,008 21.1% 2,132 95.8%

Squamous cell carcinoma 32,093 80.4% 2,419 91.1% 10,907 94.9% 954 19.9% 2,104 94.5%

(8070-8078,8083-8084)

Adenocarcinomac 4,432 11.1% 97 3.7% 186 1.6% 3,008 62.9% 73 3.3%

Other specific carcinomasd 484 1.2% - - 35 0.3% 269 5.6% - -

Unspecified, Carcinoma, NOS 1,438 3.6% - - 110 1.0% 320 6.7% - -

(8010-8011,8020-8022)

Sarcoma and soft tissuee 172 0.4% - - 22 0.2% 50 1.0% - -

Other specific typesf 207 0.5% - - - - 89 1.9% - -

Unspecified (8000-8005) 116 0.3% - - 22 0.2% 38 0.8% - -

Total 39,903 100.0% 2,656 100.0% 11,491 100.0% 4,782 100.0% 2,226 100.0%

Other

Gum and Oropharynx Oral Cavity

Other Mouth Nasopharynx and Tonsil Hypopharynx and Pharynx

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent 

Epidermoid carcinomab (8051-8131) 4,393 79.9% 1,526 61.9% 7,463 96.9% 2,351 96.2% 552 86.7%

Squamous cell carcinoma 4,167 75.8% 1,303 52.8% 7,367 95.7% 2,324 95.1% 548 86.0%

(8070-8078,8083-8084)

Adenocarcinomac 906 16.5% 65 2.6% 55 0.7% 25 1.0% 17 2.7%

Other specific carcinomasd 29 0.5% 65 2.6% 38 0.5% 22 0.9% - -

Unspecified, Carcinoma, NOS 50 0.9% 747 30.3% 121 1.6% 30 1.2% 37 5.8%

(8010-8011,8020-8022)

Sarcoma and soft tissuee 31 0.6% 38 1.5% - - - - - -

Other specific typesf 76 1.4% 16 0.6% - - - - - -

Unspecified (8000-8005) - - - - - - - - - -

Total 5,500 100.0% 2,466 100.0% 7,702 100.0% 2,443 100.0% 637 100.0%

Table 20.28

Cancer of the Oral Cavity and Pharynx (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases, 2004-2008

All Races, Both Sexes, by site
05

10

15

20

25

30

35

1975 1985 1995 2008

05

10

15

20

25

30

35

1975 1985 1995 2008

05

10

15

1975 1985 1995 2008

05

10

15

1975 1985 1995 2008

Delay-Adjusted

Incidence

Observed

Incidence

Mortality

SEER Observed Incidence, SEER Delay Adjusted Incidence and US Death Rates

Cancer of the Oral Cavity and Pharynx, by Race and Sex

a

Figure 20.1

Source: SEER 9 areas and US Mortality Files (National Center for Health Statistics, CDC).

Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).

Regression lines and APCs are calculated using the Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute.

The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.

The APC is significantly different from zero (p < 0.05).

a*

White Male Black Male White Female Black Female

Rate per 100,000 Rate per 100,000 Rate per 100,000 Rate per 100,000

Year of Diagnosis/Death Year of Diagnosis/Death Year of Diagnosis/Death Year of Diagnosis/Death

SEER Incidence APCs

Delay Adj, 2001-08 = 0.5

Observed, 2001-08 = 0.2

SEER Incidence APCs

Delay Adj, 1987-08 = -3.2*

Observed, 1987-08 = -3.2*

SEER Incidence APCs

Delay Adj, 1981-08 = -0.8*

Observed, 1981-08 = -0.9*

SEER Incidence APCs

Delay Adj, 1975-08 = -1.4*

Observed, 1975-08 = -1.5*

SEER Cancer Statistics Review 1975-2008 National Cancer Institute
Joinpoint Analyses for Whites and Blacks from 1975-2008

and for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics from 1992-2008 05

10

15

20

1975 1980 1985 1990 1995 2000 2008

05

10

15

20

1975 1980 1985 1990 1995 2000 2008

White

Black

API

AI/AN

Hispanic

SEER Incidence and US Death Rates

Cancer of the Oral Cavity and Pharynx, Both Sexes

Figure 20.2

Source: Incidence data for whites and blacks are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta). 

Incidence data for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas, San Jose-Monterey,

Los Angeles, Alaska Native Registry and Rural Georgia). Mortality data are from US Mortality Files, National Center for Health Statistics, CDC.

Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103). 

Regression lines are calculated using the Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. Joinpoint analyses for Whites and Blacks

during the 1975-2008 period allow a maximum of 5 joinpoints. Analyses for other ethnic groups during the period 1992-2008 allow a maximum of 3 joinpoints.

API = Asian/Pacific Islander.

AI/AN = American Indian/Alaska Native. Rates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics are based on

NHIA and exclude cases from the Alaska Native Registry. Mortality data for Hispanics exclude cases from Connecticut, the District of Columbia, Maine,

Maryland, Minnesota, New Hampshire, New York, North Dakota, Oklahoma, and Vermont.

Incidence Mortality

Rate per 100,000 Rate per 100,000

Year of Diagnosis Year of Death a

da

b

c

cb

d

SEER Cancer Statistics Review 1975-2008 National Cancer Institute
0123456

1975 1985 1995 2008

Joinpoint Analyses for Whites and Blacks from 1975-2008

and for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics from 1992-2008

0123456

1975 1985 1995 2008

0123456

1975 1985 1995 2008

White

Black

API

AI/AN

Hispanic

SEER Incidence Rates

Cancer of the Oral Cavity and Pharangeal for Selected Subsites, Both Sexes

Figure 20.3

Source: Incidence data for whites and blacks are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta). 

Incidence data for Asian/Pacific Islanders, American Indians/Alaska Natives and Hispanics are from the SEER 13 Areas (SEER 9 Areas, San Jose-Monterey,

Los Angeles, Alaska Native Registry and Rural Georgia). 

Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103). 

Regression lines are calculated using the Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. Joinpoint analyses for Whites and Blacks

during the 1975-2008 period allow a maximum of 5 joinpoints. Analyses for other ethnic groups during the period 1992-2008 allow a maximum of 3 joinpoints.

Regression lines could not be calculated for data series that had at least one diagnosis year with a 0 case count.

API = Asian/Pacific Islander.

AI/AN = American Indian/Alaska Native. Rates for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

Hispanic is not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics are based on

NHIA and exclude cases from the Alaska Native Registry.

Tongue Oropharynx & Tonsil

Rate per 100,000 Rate per 100,000

Year of Diagnosis Year of Diagnosis

a

da

b

c

cb

d

Nasopharynx Lip

0123456

1975 1985 1995 2008

Year of Diagnosis Year of Diagnosis

Rate per 100,000 Rate per 100,000

SEER Cancer Statistics Review 1975-2008 National Cancer Institute
05

10

15

20

25

30

35

1975 1985 1995 2008

05

10

15

20

25

30

35

1975 1985 1995 2008

05

10

15

20

25

30

35

1975 1985 1995 2008

SEER 9 Delay-Adj. Incidence SEER 9 Observed Incidence SEER 13 Delay-Adj. Incidence SEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence Rates

SEER 9 Areas Compared to SEER 13 Areas

Cancer of the Oral Cavity and Pharynx, Male, by Race

a

Figure 20.4

Source: SEER 9 areas and SEER 13 areas.

Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).

Regression lines and APCs are calculated using the Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute.

The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.

The APC is significantly different from zero (p < 0.05).

a*

All Races White Black

Rate per 100,000 Rate per 100,000 Rate per 100,000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCs

Delay Adj, 2001-08 = 0.1

Observed, 2001-08 = -0.1

SEER 13 APCs

Delay Adj, 2006-08 = 3.8

Observed, 2006-08 = 3.0

SEER 9 APCs

Delay Adj, 2001-08 = 0.5

Observed, 2001-08 = 0.2

SEER 13 APCs

Delay Adj, 2006-08 = 4.3

Observed, 2006-08 = 3.3

SEER 9 APCs

Delay Adj, 1987-08 = -3.2*

Observed, 1987-08 = -3.2*

SEER 13 APCs

Delay Adj, 1992-08 = -3.1*

Observed, 1992-08 = -3.2*

SEER Cancer Statistics Review 1975-2008 National Cancer Institute
0369

12

15

1975 1985 1995 2008

0369

12

15

1975 1985 1995 2008

0369

12

15

1975 1985 1995 2008

SEER 9 Delay-Adj. Incidence SEER 9 Observed Incidence SEER 13 Delay-Adj. Incidence SEER 13 Observed Incidence

SEER Observed Incidence and SEER Delay Adjusted Incidence Rates

SEER 9 Areas Compared to SEER 13 Areas

Cancer of the Oral Cavity and Pharynx, Female, by Race

a

Figure 20.5

Source: SEER 9 areas and SEER 13 areas.

Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).

Regression lines and APCs are calculated using the Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute.

The APC is the Annual Percent Change for the regression line segments. The APC shown on the graph is for the most recent trend.

The APC is significantly different from zero (p < 0.05).

a*

All Races White Black

Rate per 100,000 Rate per 100,000 Rate per 100,000

Year of Diagnosis Year of Diagnosis Year of Diagnosis

SEER 9 APCs

Delay Adj, 1980-08 = -0.9*

Observed, 1980-08 = -0.9*

SEER 13 APCs

Delay Adj, 1992-08 = -1.0*

Observed, 1992-08 = -1.0*

SEER 9 APCs

Delay Adj, 1981-08 = -0.8*

Observed, 1981-08 = -0.9*

SEER 13 APCs

Delay Adj, 1992-08 = -1.0*

Observed, 1992-08 = -1.1*

SEER 9 APCs

Delay Adj, 1975-08 = -1.4*

Observed, 1975-08 = -1.5*

SEER 13 APCs

Delay Adj, 1992-08 = -1.5*

Observed, 1992-08 = -1.6*

SEER Cancer Statistics Review 1975-2008 National Cancer Institute