Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

Office of Chemical Safety and Pollution Prevention

MEMORANDUM

May 3, 2012

SUBJECT: Cyprodinil – Acute and Chronic Dietary and Drinking Water Exposure and Risk 

Assessment. 

PC Code: 288202 DP Barcode: D390233 & 398362

Decision No.: 447576 & 448809 Registration No.: 100-953

Petition No.: 1E7854 & 1E7869 Regulatory Action: Section 3 

Risk Assessment Type: Dietary Case No.: NA

TXR No.: NA CAS No: 121552-61-2

MRID No.: NA 40 CFR: 180.532

FROM: Thurston G. Morton, Chemist

Risk Assessment Branch IV

Health Effects Division (7509P)

THROUGH: Doug Dotson, Chemist

Meheret Negussie, Chemist

Dietary Exposure Science Advisory Council (DESAC),

and

Susan Hummel, Senior Scientist, RAB IV

Elissa Reaves, PhD. Branch Chief

Health Effects Division (7509P)

TO: Rebecca Daiss, Risk Assessor, RAB IV

Health Effects Division (7509P)

and

Lisa Jones/Erik Kraft, RM20

Fungicide Branch

Registration Division (7505P)
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

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This document provides an acute and chronic dietary and drinking water risk analyses of 

exposures resulting from use of cyprodinil as a fungicide on food crops. This assessment 

supports requests to amend the use of cyprodinil on a number of expanded crop groups, add the 

remaining fruiting vegetables (in addition to tomato), and to add the new use on leafy petioles 

subgroup 4B. Grapes are being expanded to crop subgroup 13-07F and strawberry to 13-07G.

Executive Summary

Acute and chronic dietary risk assessments were conducted for cyprodinil using the Dietary

Exposure Evaluation Model (DEEM-FCIDTM, Version 2.03), which uses food consumption data 

from the USDA’s Continuing Surveys of Food Intakes by Individuals (CSFII) from 1994-1996 

and 1998. 

 

Acute Dietary Exposure Analysis Results and Characterization

A conservative acute dietary exposure analysis was performed for the general U.S. population 

and various population subgroups. Tolerance level residues and 100 % crop treated assumptions 

were used. DEEM default and empirical processing factors were used to modify the tolerance 

values. The acute analysis incorporated the 1 in 10 year peak surface drinking water estimate 

from application of cyprodinil to grapes. The resulting 95th percentile acute exposure estimates 

are not of concern for the general U.S. population or any of the other population subgroups. The 

subgroup with the highest risk estimate is children 1-2 years old with a % acute population 

adjusted dose (aPAD) of 8%. The% aPAD for the general U.S. population is 5%. 

Chronic Dietary Exposure Analysis Results and Characterization

A moderately refined chronic dietary exposure analysis was performed for the general U.S. 

population and various population subgroups. For the chronic dietary analysis, tolerance level 

residues for most commodities; average field trial residues for pome fruit, head lettuce, leaf 

lettuce, and grapes; and 100% crop treated assumptions were used. DEEM default and empirical 

processing factors were used to modify the tolerance values. The chronic analysis incorporated 

the 10 year average surface drinking water estimate from application of cyprodinil to grapes. 

Chronic dietary risk estimates are not of concern for the general U.S. population or any of the 

other population subgroups. The subgroup with the highest risk estimate is children 1-2 years 

old with a % chronic PAD (cPAD) of 75%. The% cPAD for the general U.S. population is 28%.

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 

and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the PAD. The PAD is equivalent to the point of departure (POD, 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

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NOAEL, LOAEL, etc) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk 

exceeds 100% of the PAD. References that discuss the acute and chronic risk assessments in 

more detail are available on the EPA/pesticides web site: “Available Information on Assessing 

Exposure from Pesticides, A User’s Guide,” 6/21/2000, web link: 

http://www.epa.gov/fedrgstr/EPA_PEST/2000/July/Day_12/6061.pdf ; or see SOP 99.6 

(8/20/99).

II. Residue Information

Residues of Concern 

The metabolism of cyprodinil has been studied in apple, peach, potato, tomato, and wheat. The 

residue of concern in plants is the parent compound cyprodinil as determined by the HED 

Metabolism Assessment Review Committee (MARC) (D243198, G. Kramer, 3/11/98). The 

nature of the residue in ruminants is adequately understood based on acceptable lactating goat 

metabolism studies. HED has concluded that the residues of concern for both risk assessment 

and the tolerance definition should include the combined residues of cyprodinil and free and 

conjugated CGA-304075, expressed in parent equivalents (D345970 and D345182, G. Kramer, 

6/4/08). The water residues of concern as determined by MARC are the parent and CGA 249287 

(4-cyclopropyl-6-methylpyrimidin-2-amine) (D292557, 6/8/03). HED continues to consider 

these metabolites and degradates to be the residues of concern.

Table 1: Summary of Residues of Concern for Cyprodinil

Matrix Residues of Concern

For Risk Assessment For Tolerance Expression

Plants cyprodinil cyprodinil

Livestock cyprodinil and CGA-304075 cyprodinil and CGA-304075

Water cyprodinil and CGA 249287 cyprodinil

Established/Recommended Tolerances

Permanent tolerances are established (40 CFR §180.532(a)) for residues of cyprodinil per se

in/on a variety of crop commodities, at levels ranging from 0.02 ppm in/on almonds to 340 ppm 

in citrus oil. Recommended tolerances for the proposed amended/new uses are as follows

(D389554, T. Morton, 05/3//2012). 
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Onion, bulb, subgroup 3-07A..... ................................................................0.6 ppm

Onion, green, subgroup 3-07B.....................................................................4.0 ppm

Caneberry subgroup 13-07A.......................................................10 ppm

Bushberry subgroup 13-07B.....................................................................3.0 ppm

Fruit, small vine climbing, except fuzzy kiwifruit, subgroup 13-07F, ........2.0 ppm

Berry, low growing subgroup 13-07G, except cranberry.............................5.0 ppm

Dragon fruit ................................................................................................2.0 ppm

Fruit, pome, group 11-10 .............................................................................1.7 ppm

Vegetable, fruiting, group 8-10....................................................................1.5 ppm

Vegetable, leafy, except brassica, subgroup 4A.......................................50 ppm

Leafy petiole subgroup 04B.......................................................................30 ppm

Citrus, oil...............................................................................60 ppm

HED continues to recommend that the current tolerance expression for animal commodities be 

changed to reflect both parent and metabolite CGA-304075 (4-[(4-cyclopropyl-6-methyl-2-2-

pyrimidinyl)amino]-phenol).

Residues Used in the Acute and Chronic Analysis

For the acute dietary analysis, tolerance level residues and 100% crop treated assumptions were 

used for all treated commodities. For the chronic dietary analysis, tolerance level residues for 

most commodities; average field trial residues for pome fruit, head lettuce, leaf lettuce, spinach, 

tomato, lemon, and grapes; and 100% crop treated assumptions were used. Default processing 

factors were used for most processed commodities, except for tomato paste/puree in the 

chronic(1x) and lemon/lime juice (1x). Residues used in the acute and chronic dietary analysis 

are provided in Table 2. Average residues where noted were used in the chronic dietary analysis.
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Table 2. Residue Estimates Used in the Cyprodinil Acute and Chronic Dietary/Drinking Water Analysis

Commodity Tolerance (ppm)

Crop Subgroup 1B, except sugarbeet 0.75

Crop Group 2 10

Onion, bulb subgroup 3-07A 0.6

Onion, green subgroup 3-07B 4.0

Crop Subgroup 4A (except spinach) 

30 tolerance/0.87 avg head lettuce

30 tolerance/13 avg leaf lettuce

Crop Subgroup 4B 30

Crop Subgroup 5A Head and stem 1.0

Crop Subgroup 5B Leafy Brassica greens 10

Bean, dry; Bean, succulent 0.6

Vegetable, fruiting, group 8-10 1.5

Crop Group 9 0.7

Lemon, Lime 0.6

Citrus Oil Decreased to 60

Pome fruit, Crop group 11-10

1.7 tolerance/0.50 avg apple

1.7 tolerance/0.38 avg pear

Stone fruit, Crop group 12 2

Caneberry, subgroup 13-07A 10

Bushberry subgroup 13-07B 3

Small fruit vine climbing subgroup 13-07F, except fuzzy kiwifruit 2.0 tolerance/0.81 avg grapes

Low growing berry subgroup 13-07G, except cranberry 5.0 (inc. strawberry)

Almond 0.02

Pistachio 0.1

Crop Subgroup 19A Herb Fresh (except parsley) 3

Crop Subgroup 19A Herb Dried (except parsley) 15

Parsley, dried leaves 170

Parsley leaves 35

Rape seed oil (canola, seed) 0.03

Avocado, Canistel; Mango; Papaya; Sapodilla; Sapote, black; Sapote, 

mamey; Star apple

1.2

Dragonfruit 2.0

Kiwifruit 1.8

Watercress 20

Beef, Goat, Horse, Sheep, meat byproducts (including liver and kidney ) 0.02

Grape, raisin 3.0

Turnip, greens 10.0

III. Water Data

Drinking water residues were incorporated directly into the acute and chronic dietary analyses as

“water, direct, all sources” and “water, indirect, all sources” and were provided by the 

Environmental Fate and Effects Division (EFED) (D391853, J Melendez 11/4/11). EFED 

generated the surface water estimates using the linked Pesticide Root Zone/Exposure Analysis 

Modeling System (PRZM-EXAMS) Tier 2 aquatic models. Ground water estimates were 

calculated using the Tier 1 Screening Concentration In GROund Water (SCI-GROW) model. 
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Estimated Drinking Water Concentrations (EDWCs) for cyprodinil and its metabolite CGA249287 were derived based on a maximum application rate of 0.47 lb a.i./A applied 3 times/year, 

or 1.4 lb a.i./A/year, on grapes. The concentrations have been adjusted with the Percent Crop 

Area (PCA) of 0.87 for a national assessment. Combined surface water EDWCs for cyprodinil

and CGA-249287 used in the exposure assessment, are provided in Table 3. 

Table 3. EDWCs for the Cyprodinil Human Health Risk Assessment 

Drinking Water Source Peak (μg/L) Annual Mean (μg/L)

Surface Water 34.79 24.65

Ground Water 0.0861 0.0861

IV. DEEM-FCIDTM Program and Consumption Information

Cyprodinil chronic dietary exposure assessments were conducted using the Dietary Exposure 

Evaluation Model software with the Food Commodity Intake Database (DEEM-FCIDTM, Version 

2.03), which incorporates consumption data from USDA’s Continuing Surveys of Food Intakes 

by Individuals (CSFII), 1994-1996 and 1998. The 1994-96, 98 data are based on the reported 

consumption of more than 20,000 individuals over two non-consecutive survey days. Foods “as 

consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g. apples, peeled 

fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly

available recipe translation files developed jointly by USDA/ARS and EPA. For chronic 

exposure assessment, consumption data are averaged for the entire U.S. population and within 

population subgroups, but for acute exposure assessment are retained as individual consumption 

events. Based on analysis of the 1994-96, 98 CSFII consumption data, which took into account 

dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk 

for the following population subgroups: the general U.S. population, all infants (<1 year old), 

children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 

50+ years old.

For chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form. The resulting residue consumption 

estimate for each food/food form is summed with the residue consumption estimates for all other 

food/food forms on the commodity residue list to arrive at the total average estimated exposure. 

Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD. This procedure 

is performed for each population subgroup.
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V. Toxicological Information

HED evaluated the toxicology data base for cyprodinil and selected doses and endpoints for chronic 

dietary and drinking water risk assessments provided in Table 4. 

Table 4. Summary of Toxicological Doses and Endpoints for Cyprodinil for Use in Dietary Human Health Risk Assessments

Exposure/Scenario Point of 

Departure

Uncertainty/F

QPA Safety 

Factors

RfD, PAD, LOC 

for Risk 

Assessment

Study and Toxicological Effects

Acute Dietary

(All Populations)

NOAEL = 200 

mg/kg/day

UFA= 10x

UFH=10x

FQPA SF= 1x

Acute RfD = 2.0

mg/kg/day 

aPAD = 2.0

mg/kg/day 

Acute Neurotoxicity - Rat

LOAEL = 600 mg/kg/day based on clinical 

signs of toxicity, low motor activity and 

reversible hypothermia

Chronic Dietary 

(All Populations)

NOAEL= 2.7

mg/kg/day

UFA = 10x

UFH =10x

FQPA SF= 1x

Chronic RfD = 

0.027

mg/kg/day

cPAD = 

0.027mg/kg/day

2-Year Chronic Toxicity/ Carcinogenicity- rat

LOAEL = 35.6 mg/kg/day based on 

degenerative liver lesions (spongiosis hepatis) 

in males.

Cancer (all routes) Classification: “Not likely to be carcinogenic to humans”

Point of Departure (POD) = A data point or an estimated point that is derived from observed dose-response data and used to mark the beginning of 

extrapolation to determine risk associated with lower environmentally relevant human exposures. 

NOAEL = no observed adverse effect level. 

LOAEL = lowest observed adverse effect level. 

UF = uncertainty factor. 

UFA = extrapolation from animal to human (interspecies). 

UFH = potential variation in sensitivity among members of the human population (intraspecies). 

FQPA SF = FQPA Safety Factor. 

PAD = population adjusted dose (a = acute, c = chronic). 

RfD = reference dose. 

VI. Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 

100% of the PAD. The DEEM-FCIDTM analyses estimate the dietary exposure of the U.S. 

population and various population subgroups. The results reported in Tables 5 & 6 are for the 

general U.S. Population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 

13-19, females 13-49, adults 20-49, and adults 50+ years.

Results of Acute Dietary Exposure Analysis

The results of the acute dietary exposure analysis are reported in Table 5. 
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Table 5: Summary of Acute Dietary Exposure and Risk for Cyprodinil

Population Subgroup aPAD (mg/kg/day) Acute (95th Percentile)

Exposure (mg/kg/day) %aPAD

General U.S. Population

2.0

0.095794 4.8

All Infants (< 1 year old) 0.102882 5.1

Children 1-2 years old 0.151445 7.6

Children 3-5 years old 0.131883 6.6

Children 6-12 years old 0.098193 4.9

Youth 13-19 years old 0.080270 4.0

Adults 20-49 years old 0.092162 4.6

Adults 50+ years old 0.085400 4.3

Females 13-49 years old 0.099465 5.0

Results of Chronic Dietary Exposure Analysis

The results of the chronic dietary exposure analysis are reported in Table 6. 

Table 6: Summary of Chronic Dietary Exposure and Risk for Cyprodinil

Population Subgroup cPAD (mg/kg/day) Chronic

Exposure (mg/kg/day) % cPAD

General U.S. Population

0.027

0.007421 28

All Infants (< 1 year old) 0.014099 52

Children 1-2 years old 0.020269 75

Children 3-5 years old 0.015148 56

Children 6-12 years old 0.008552 32

Youth 13-19 years old 0.005195 19

Adults 20-49 years old 0.005818 22

Adults 50+ years old 0.007260 27

Females 13-49 years old 0.006066 23

VII. Characterization of Inputs/Outputs

For the acute dietary analysis, tolerance level residues and 100% crop treated assumptions were 

used for all treated commodities. For the chronic dietary analysis, tolerance level residues for 

most commodities; average field trial residues for pome fruit, head lettuce, leaf lettuce, spinach, 

tomatoes, lemon, and grapes; and 100% crop treated assumptions were used. Default processing 

factors were used for all processed commodities except tomato paste/puree (1x) and and 

lemon/lime juice (1x). Residues do not warrant further refinement at this time.

VIII. Conclusions

An acute and chronic dietary exposure analyses was performed for the general U.S. population 

and various population subgroups. The acute and chronic risk estimates are below HED’s level 

of concern. HED is confident the acute and chronic dietary exposures to cyprodinil are not 

underestimated.
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IX. List of Attachments

1. Acute DEEM-FCID Residue Input File.

2. Results of Acute DEEM-FCID Dietary Exposure Analysis.

3. Chronic DEEM-FCID Residue Input File.

4. Results of Chronic DEEM-FCID Dietary Exposure Analysis.
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Attachment 1 Acute DEEM-FCID Residue Input File

Filename: C:\Documents and Settings\tmorton\My Documents\MyFiles\DEEM Files\288202 

Cyprodinil\Leafy Petioles 1E7869 and Misc 1E7854\288202acuteEPArecommendations.R98

Chemical: cyprodinil

RfD(Chronic): .03 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 2 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 03-13-2012/10:38:56/8 Program ver. 2.03

--------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ -------

01010500 1AB Beet, garden, roots 0.750000 1.000 1.000 

01010501 1AB Beet, garden, roots-babyfood 0.750000 1.000 1.000 

01010670 1AB Burdock 0.750000 1.000 1.000 

01010780 1AB Carrot 0.750000 1.000 1.000 

01010781 1AB Carrot-babyfood 0.750000 1.000 1.000 

01010790 1AB Carrot, juice 0.750000 1.000 1.000 

01010840 1AB Celeriac 0.750000 1.000 1.000 

01011000 1AB Chicory, roots 0.750000 1.000 1.000 

01011680 1AB Ginseng, dried 0.750000 1.000 1.000 

01011900 1AB Horseradish 0.750000 1.000 1.000 

01012500 1AB Parsley, turnip rooted 0.750000 1.000 1.000 

01012510 1AB Parsnip 0.750000 1.000 1.000 

01012511 1AB Parsnip-babyfood 0.750000 1.000 1.000 

01013140 1AB Radish, roots 0.750000 1.000 1.000 

01013160 1AB Radish, Oriental, roots 0.750000 1.000 1.000 

01013270 1AB Rutabaga 0.750000 1.000 1.000 

01013310 1AB Salsify, roots 0.750000 1.000 1.000 

01013880 1AB Turnip, roots 0.750000 1.000 1.000 

02000510 2 Beet, garden, tops 10.000000 1.000 1.000 

02001010 2 Chicory, tops 10.000000 1.000 1.000 

02001400 2 Dasheen, leaves 10.000000 1.000 1.000 

02003150 2 Radish, tops 10.000000 1.000 1.000 

02003170 2 Radish, Oriental, tops 10.000000 1.000 1.000 

02003320 2 Salsify, tops 10.000000 1.000 1.000 

03001640 3 Garlic 0.600000 1.000 1.000 

03001650 3 Garlic, dried 0.600000 1.000 1.000 

03001651 3 Garlic, dried-babyfood 0.600000 1.000 1.000 

03001980 3 Leek 4.000000 1.000 1.000 

03002370 3 Onion, dry bulb 0.600000 1.000 1.000 

03002371 3 Onion, dry bulb-babyfood 0.600000 1.000 1.000 

03002380 3 Onion, dry bulb, dried 0.600000 9.000 1.000 

03002381 3 Onion, dry bulb, dried-babyfood 0.600000 9.000 1.000 

03002390 3 Onion, green 4.000000 1.000 1.000 

03003380 3 Shallot 4.000000 1.000 1.000 

04010050 4A Amaranth, leafy 50.000000 1.000 1.000 

04010180 4A Arugula 50.000000 1.000 1.000 

04011040 4A Chrysanthemum, garland 50.000000 1.000 1.000 

04011330 4A Cress, garden 50.000000 1.000 1.000 

04011340 4A Cress, upland 50.000000 1.000 1.000 

04011380 4A Dandelion, leaves 50.000000 1.000 1.000 

04011500 4A Endive 50.000000 1.000 1.000 

04012040 4A Lettuce, head 50.000000 1.000 1.000 

04012050 4A Lettuce, leaf 50.000000 1.000 1.000 

04012480 4A Parsley, leaves 50.000000 1.000 1.000 

04013130 4A Radicchio 50.000000 1.000 1.000 

04013550 4A Spinach 50.000000 1.000 1.000 

04013551 4A Spinach-babyfood 50.000000 1.000 1.000 

04020760 4B Cardoon 30.000000 1.000 1.000 

04020850 4B Celery 30.000000 1.000 1.000 

04020851 4B Celery-babyfood 30.000000 1.000 1.000 

04020860 4B Celery, juice 30.000000 1.000 1.000 

04020870 4B Celtuce 30.000000 1.000 1.000 

04021520 4B Fennel, Florence 30.000000 1.000 1.000 

04023220 4B Rhubarb 30.000000 1.000 1.000 

04023670 4B Swiss chard 30.000000 1.000 1.000 

05010610 5A Broccoli 1.000000 1.000 1.000 
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05010611 5A Broccoli-babyfood 1.000000 1.000 1.000 

05010620 5A Broccoli, Chinese 1.000000 1.000 1.000 

05010640 5A Brussels sprouts 1.000000 1.000 1.000 

05010690 5A Cabbage 1.000000 1.000 1.000 

05010710 5A Cabbage, Chinese, napa 1.000000 1.000 1.000 

05010720 5A Cabbage, Chinese, mustard 1.000000 1.000 1.000 

05010830 5A Cauliflower 1.000000 1.000 1.000 

05011960 5A Kohlrabi 1.000000 1.000 1.000 

05020630 5B Broccoli raab 10.000000 1.000 1.000 

05020700 5B Cabbage, Chinese, bok choy 10.000000 1.000 1.000 

05021170 5B Collards 10.000000 1.000 1.000 

05021940 5B Kale 10.000000 1.000 1.000 

05022290 5B Mustard greens 10.000000 1.000 1.000 

05023180 5B Rape greens 10.000000 1.000 1.000 

05023890 5B Turnip, greens 10.000000 1.000 1.000 

06020310 6B Bean, broad, succulent 0.600000 1.000 1.000 

06020330 6B Bean, cowpea, succulent 0.600000 1.000 1.000 

06020370 6B Bean, lima, succulent 0.600000 1.000 1.000 

06030300 6C Bean, black, seed 0.600000 1.000 1.000 

06030320 6C Bean, broad, seed 0.600000 1.000 1.000 

06030340 6C Bean, cowpea, seed 0.600000 1.000 1.000 

06030350 6C Bean, great northern, seed 0.600000 1.000 1.000 

06030360 6C Bean, kidney, seed 0.600000 1.000 1.000 

06030380 6C Bean, lima, seed 0.600000 1.000 1.000 

06030390 6C Bean, mung, seed 0.600000 1.000 1.000 

06030400 6C Bean, navy, seed 0.600000 1.000 1.000 

06030410 6C Bean, pink, seed 0.600000 1.000 1.000 

06030420 6C Bean, pinto, seed 0.600000 1.000 1.000 

06030980 6C Chickpea, seed 0.600000 1.000 1.000 

06030981 6C Chickpea, seed-babyfood 0.600000 1.000 1.000 

06030990 6C Chickpea, flour 0.600000 1.000 1.000 

06031820 6C Guar, seed 0.600000 1.000 1.000 

06031821 6C Guar, seed-babyfood 0.600000 1.000 1.000 

06032030 6C Lentil, seed 0.600000 1.000 1.000 

08001480 8 Eggplant 1.500000 1.000 1.000 

08002340 8 Okra 1.500000 1.000 1.000 

08002700 8 Pepper, bell 1.500000 1.000 1.000 

08002701 8 Pepper, bell-babyfood 1.500000 1.000 1.000 

08002710 8 Pepper, bell, dried 1.500000 1.000 1.000 

08002711 8 Pepper, bell, dried-babyfood 1.500000 1.000 1.000 

08002720 8 Pepper, nonbell 1.500000 1.000 1.000 

08002721 8 Pepper, nonbell-babyfood 1.500000 1.000 1.000 

08002730 8 Pepper, nonbell, dried 1.500000 1.000 1.000 

08003740 8 Tomatillo 1.500000 1.000 1.000 

08003750 8 Tomato 1.500000 1.000 1.000 

08003751 8 Tomato-babyfood 1.500000 1.000 1.000 

08003760 8 Tomato, paste 1.500000 1.000 1.000 

08003761 8 Tomato, paste-babyfood 1.500000 1.000 1.000 

08003770 8 Tomato, puree 1.500000 1.000 1.000 

08003771 8 Tomato, puree-babyfood 1.500000 1.000 1.000 

08003780 8 Tomato, dried 1.500000 14.300 1.000 

08003781 8 Tomato, dried-babyfood 1.500000 14.300 1.000 

08003790 8 Tomato, juice 1.500000 1.000 1.000 

09010750 9A Cantaloupe 0.700000 1.000 1.000 

09010800 9A Casaba 0.700000 1.000 1.000 

09011870 9A Honeydew melon 0.700000 1.000 1.000 

09013990 9A Watermelon 0.700000 1.000 1.000 

09014000 9A Watermelon, juice 0.700000 1.000 1.000 

09020210 9B Balsam pear 0.700000 1.000 1.000 

09020880 9B Chayote, fruit 0.700000 1.000 1.000 

09021020 9B Chinese waxgourd 0.700000 1.000 1.000 

09021350 9B Cucumber 0.700000 1.000 1.000 

09023080 9B Pumpkin 0.700000 1.000 1.000 

09023090 9B Pumpkin, seed 0.700000 1.000 1.000 

09023560 9B Squash, summer 0.700000 1.000 1.000 

09023561 9B Squash, summer-babyfood 0.700000 1.000 1.000 

09023570 9B Squash, winter 0.700000 1.000 1.000 

09023571 9B Squash, winter-babyfood 0.700000 1.000 1.000 

10001080 10 Citrus, oil 60.000000 1.000 1.000 

10001990 10 Lemon 0.600000 1.000 1.000 
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10002000 10 Lemon, juice 0.600000 1.000 1.000 

10002001 10 Lemon, juice-babyfood 0.600000 1.000 1.000 

10002010 10 Lemon, peel 0.600000 1.000 1.000 

10002060 10 Lime 0.600000 1.000 1.000 

10002070 10 Lime, juice 0.600000 1.000 1.000 

10002071 10 Lime, juice-babyfood 0.600000 1.000 1.000 

11000070 11 Apple, fruit with peel 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000080 11 Apple, peeled fruit 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000081 11 Apple, peeled fruit-babyfood 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000090 11 Apple, dried 1.700000 8.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000091 11 Apple, dried-babyfood 1.700000 8.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000100 11 Apple, juice 1.700000 1.300 1.000 PP#0F7

 Full comment: PP#0F7696

11000101 11 Apple, juice-babyfood 1.700000 1.300 1.000 PP#0F7

 Full comment: PP#0F7696

11000110 11 Apple, sauce 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000111 11 Apple, sauce-babyfood 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11001290 11 Crabapple 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002100 11 Loquat 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002660 11 Pear 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002661 11 Pear-babyfood 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002670 11 Pear, dried 1.700000 6.250 1.000 PP#0F7

 Full comment: PP#0F7696

11002680 11 Pear, juice 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002681 11 Pear, juice-babyfood 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11003100 11 Quince 1.700000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

12000120 12 Apricot 2.000000 1.000 1.000 

12000121 12 Apricot-babyfood 2.000000 1.000 1.000 

12000130 12 Apricot, dried 2.000000 6.000 1.000 

12000140 12 Apricot, juice 2.000000 1.000 1.000 

12000141 12 Apricot, juice-babyfood 2.000000 1.000 1.000 

12000900 12 Cherry 2.000000 1.000 1.000 

12000901 12 Cherry-babyfood 2.000000 1.000 1.000 

12000910 12 Cherry, juice 2.000000 1.500 1.000 

12000911 12 Cherry, juice-babyfood 2.000000 1.500 1.000 

12002300 12 Nectarine 2.000000 1.000 1.000 

12002600 12 Peach 2.000000 1.000 1.000 

12002601 12 Peach-babyfood 2.000000 1.000 1.000 

12002610 12 Peach, dried 2.000000 7.000 1.000 

12002611 12 Peach, dried-babyfood 2.000000 7.000 1.000 

12002620 12 Peach, juice 2.000000 1.000 1.000 

12002621 12 Peach, juice-babyfood 2.000000 1.000 1.000 

12002850 12 Plum 2.000000 1.000 1.000 

12002851 12 Plum-babyfood 2.000000 1.000 1.000 

12002860 12 Plum, prune, fresh 2.000000 1.000 1.000 

12002861 12 Plum, prune, fresh-babyfood 2.000000 1.000 1.000 

12002870 12 Plum, prune, dried 2.000000 5.000 1.000 

12002871 12 Plum, prune, dried-babyfood 2.000000 5.000 1.000 

12002880 12 Plum, prune, juice 2.000000 1.400 1.000 

12002881 12 Plum, prune, juice-babyfood 2.000000 1.400 1.000 

13010550 13A Blackberry 10.000000 1.000 1.000 

13010560 13A Blackberry, juice 10.000000 1.000 1.000 

13010561 13A Blackberry, juice-babyfood 10.000000 1.000 1.000 

13010580 13A Boysenberry 10.000000 1.000 1.000 

13011420 13A Dewberry 10.000000 1.000 1.000 

13012080 13A Loganberry 10.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 13 of 21

13013200 13A Raspberry 10.000000 1.000 1.000 

13013201 13A Raspberry-babyfood 10.000000 1.000 1.000 

13013210 13A Raspberry, juice 10.000000 1.000 1.000 

13013211 13A Raspberry, juice-babyfood 10.000000 1.000 1.000 

13020570 13B Blueberry 3.000000 1.000 1.000 

13020571 13B Blueberry-babyfood 3.000000 1.000 1.000 

13021360 13B Currant 3.000000 1.000 1.000 

13021370 13B Currant, dried 3.000000 1.000 1.000 

13021490 13B Elderberry 3.000000 1.000 1.000 

13021740 13B Gooseberry 3.000000 1.000 1.000 

13021910 13B Huckleberry 3.000000 1.000 1.000 

14000030 14 Almond 0.020000 1.000 1.000 

14000031 14 Almond-babyfood 0.020000 1.000 1.000 

14000040 14 Almond, oil 0.020000 1.000 1.000 

14000041 14 Almond, oil-babyfood 0.020000 1.000 1.000 

14002820 14 Pistachio 0.100000 1.000 1.000 

19010280 19A Basil, fresh leaves 3.000000 1.000 1.000 

19010281 19A Basil, fresh leaves-babyfood 3.000000 1.000 1.000 

19010290 19A Basil, dried leaves 15.000000 1.000 1.000 

19010291 19A Basil, dried leaves-babyfood 15.000000 1.000 1.000 

19011030 19A Chive 3.000000 1.000 1.000 

19011180 19A Coriander, leaves 3.000000 1.000 1.000 

19011181 19A Coriander, leaves-babyfood 3.000000 1.000 1.000 

19011440 19A Dillweed 3.000000 1.000 1.000 

19011840 19A Herbs, other 3.000000 1.000 1.000 

19011841 19A Herbs, other-babyfood 3.000000 1.000 1.000 

19012020 19A Lemongrass 3.000000 1.000 1.000 

19012200 19A Marjoram 3.000000 1.000 1.000 

19012201 19A Marjoram-babyfood 3.000000 1.000 1.000 

19012490 19A Parsley, dried leaves 170.000000 1.000 1.000 

19012491 19A Parsley, dried leaves-babyfood 170.000000 1.000 1.000 

19013340 19A Savory 3.000000 1.000 1.000 

20003190 20 Rapeseed, oil 0.030000 1.000 1.000 

20003191 20 Rapeseed, oil-babyfood 0.030000 1.000 1.000 

21000460 M Beef, meat byproducts 0.020000 1.000 1.000 

21000461 M Beef, meat byproducts-babyfood 0.020000 1.000 1.000 

21000480 M Beef, kidney 0.020000 1.000 1.000 

21000490 M Beef, liver 0.020000 1.000 1.000 

21000491 M Beef, liver-babyfood 0.020000 1.000 1.000 

23001700 M Goat, meat byproducts 0.020000 1.000 1.000 

23001720 M Goat, kidney 0.020000 1.000 1.000 

23001730 M Goat, liver 0.020000 1.000 1.000 

26003400 M Sheep, meat byproducts 0.020000 1.000 1.000 

26003420 M Sheep, kidney 0.020000 1.000 1.000 

26003430 M Sheep, liver 0.020000 1.000 1.000 

86010000 O Water, direct, all sources 0.034790 1.000 1.000 

86020000 O Water, indirect, all sources 0.034790 1.000 1.000 

95000200 O Avocado 1.200000 1.000 1.000 

95000740 O Canistel 1.200000 1.000 1.000 

95001750 O Grape 2.000000 1.000 1.000 

95001760 O Grape, juice 2.000000 1.200 1.000 

95001761 O Grape, juice-babyfood 2.000000 1.200 1.000 

95001770 O Grape, leaves 2.000000 1.000 1.000 

95001780 O Grape, raisin 3.000000 1.000 1.000 

95001790 O Grape, wine and sherry 2.000000 1.000 1.000 

95001950 O Kiwifruit 1.800000 1.000 1.000 

95002090 O Longan 2.000000 1.000 1.000 

95002110 O Lychee 2.000000 1.000 1.000 

95002120 O Lychee, dried 2.000000 1.850 1.000 

95002150 O Mango 1.200000 1.000 1.000 

95002151 O Mango-babyfood 1.200000 1.000 1.000 

95002160 O Mango, dried 1.200000 1.000 1.000 

95002170 O Mango, juice 1.200000 1.000 1.000 

95002171 O Mango, juice-babyfood 1.200000 1.000 1.000 

95002450 O Papaya 1.200000 1.000 1.000 

95002451 O Papaya-babyfood 1.200000 1.000 1.000 

95002460 O Papaya, dried 1.200000 1.800 1.000 

95002470 O Papaya, juice 1.200000 1.500 1.000 

95003330 O Sapote, Mamey 1.200000 1.000 1.000 

95003510 O Spanish lime 2.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 14 of 21

95003590 O Strawberry 5.000000 1.000 1.000 

95003591 O Strawberry-babyfood 5.000000 1.000 1.000 

95003600 O Strawberry, juice 5.000000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 5.000000 1.000 1.000 

95003980 O Watercress 20.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 15 of 21

Attachment 2 Chronic DEEM-FCID Residue Input File

Filename: C:\Documents and Settings\tmorton\My Documents\MyFiles\DEEM Files\288202 

Cyprodinil\Leafy Petioles 1E7869 and Misc 1E7854\288202chronicEPArecommendations.R98

Chemical: cyprodinil

RfD(Chronic): .03 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 1.5 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 03-13-2012/10:58:02/8 Program ver. 2.03

--------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ -------

01010500 1AB Beet, garden, roots 0.750000 1.000 1.000 

01010501 1AB Beet, garden, roots-babyfood 0.750000 1.000 1.000 

01010670 1AB Burdock 0.750000 1.000 1.000 

01010780 1AB Carrot 0.750000 1.000 1.000 

01010781 1AB Carrot-babyfood 0.750000 1.000 1.000 

01010790 1AB Carrot, juice 0.750000 1.000 1.000 

01010840 1AB Celeriac 0.750000 1.000 1.000 

01011000 1AB Chicory, roots 0.750000 1.000 1.000 

01011680 1AB Ginseng, dried 0.750000 1.000 1.000 

01011900 1AB Horseradish 0.750000 1.000 1.000 

01012500 1AB Parsley, turnip rooted 0.750000 1.000 1.000 

01012510 1AB Parsnip 0.750000 1.000 1.000 

01012511 1AB Parsnip-babyfood 0.750000 1.000 1.000 

01013140 1AB Radish, roots 0.750000 1.000 1.000 

01013160 1AB Radish, Oriental, roots 0.750000 1.000 1.000 

01013270 1AB Rutabaga 0.750000 1.000 1.000 

01013310 1AB Salsify, roots 0.750000 1.000 1.000 

01013880 1AB Turnip, roots 0.750000 1.000 1.000 

02000510 2 Beet, garden, tops 10.000000 1.000 1.000 

02001010 2 Chicory, tops 10.000000 1.000 1.000 

02001400 2 Dasheen, leaves 10.000000 1.000 1.000 

02003150 2 Radish, tops 10.000000 1.000 1.000 

02003170 2 Radish, Oriental, tops 10.000000 1.000 1.000 

02003320 2 Salsify, tops 10.000000 1.000 1.000 

03001640 3 Garlic 0.600000 1.000 1.000 

03001650 3 Garlic, dried 0.600000 1.000 1.000 

03001651 3 Garlic, dried-babyfood 0.600000 1.000 1.000 

03001980 3 Leek 4.000000 1.000 1.000 

03002370 3 Onion, dry bulb 0.600000 1.000 1.000 

03002371 3 Onion, dry bulb-babyfood 0.600000 1.000 1.000 

03002380 3 Onion, dry bulb, dried 0.600000 9.000 1.000 

03002381 3 Onion, dry bulb, dried-babyfood 0.600000 9.000 1.000 

03002390 3 Onion, green 4.000000 1.000 1.000 

03003380 3 Shallot 4.000000 1.000 1.000 

04010050 4A Amaranth, leafy 50.000000 1.000 1.000 

04010180 4A Arugula 50.000000 1.000 1.000 

04011040 4A Chrysanthemum, garland 50.000000 1.000 1.000 

04011330 4A Cress, garden 50.000000 1.000 1.000 

04011340 4A Cress, upland 50.000000 1.000 1.000 

04011380 4A Dandelion, leaves 50.000000 1.000 1.000 

04011500 4A Endive 50.000000 1.000 1.000 

04012040 4A Lettuce, head 0.870000 1.000 1.000 

04012050 4A Lettuce, leaf 13.000000 1.000 1.000 

04012480 4A Parsley, leaves 35.000000 1.000 1.000 

04013130 4A Radicchio 50.000000 1.000 1.000 

04013550 4A Spinach 11.800000 1.000 1.000 

04013551 4A Spinach-babyfood 11.800000 1.000 1.000 

04020760 4B Cardoon 30.000000 1.000 1.000 

04020850 4B Celery 30.000000 1.000 1.000 

04020851 4B Celery-babyfood 30.000000 1.000 1.000 

04020860 4B Celery, juice 30.000000 1.000 1.000 

04020870 4B Celtuce 30.000000 1.000 1.000 

04021520 4B Fennel, Florence 30.000000 1.000 1.000 

04023220 4B Rhubarb 30.000000 1.000 1.000 

04023670 4B Swiss chard 30.000000 1.000 1.000 

05010610 5A Broccoli 1.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 16 of 21

05010611 5A Broccoli-babyfood 1.000000 1.000 1.000 

05010620 5A Broccoli, Chinese 1.000000 1.000 1.000 

05010640 5A Brussels sprouts 1.000000 1.000 1.000 

05010690 5A Cabbage 1.000000 1.000 1.000 

05010710 5A Cabbage, Chinese, napa 1.000000 1.000 1.000 

05010720 5A Cabbage, Chinese, mustard 1.000000 1.000 1.000 

05010830 5A Cauliflower 1.000000 1.000 1.000 

05011960 5A Kohlrabi 1.000000 1.000 1.000 

05020630 5B Broccoli raab 10.000000 1.000 1.000 

05020700 5B Cabbage, Chinese, bok choy 10.000000 1.000 1.000 

05021170 5B Collards 10.000000 1.000 1.000 

05021940 5B Kale 10.000000 1.000 1.000 

05022290 5B Mustard greens 10.000000 1.000 1.000 

05023180 5B Rape greens 10.000000 1.000 1.000 

05023890 5B Turnip, greens 10.000000 1.000 1.000 

06020310 6B Bean, broad, succulent 0.600000 1.000 1.000 

06020330 6B Bean, cowpea, succulent 0.600000 1.000 1.000 

06020370 6B Bean, lima, succulent 0.600000 1.000 1.000 

06030300 6C Bean, black, seed 0.600000 1.000 1.000 

06030320 6C Bean, broad, seed 0.600000 1.000 1.000 

06030340 6C Bean, cowpea, seed 0.600000 1.000 1.000 

06030350 6C Bean, great northern, seed 0.600000 1.000 1.000 

06030360 6C Bean, kidney, seed 0.600000 1.000 1.000 

06030380 6C Bean, lima, seed 0.600000 1.000 1.000 

06030390 6C Bean, mung, seed 0.600000 1.000 1.000 

06030400 6C Bean, navy, seed 0.600000 1.000 1.000 

06030410 6C Bean, pink, seed 0.600000 1.000 1.000 

06030420 6C Bean, pinto, seed 0.600000 1.000 1.000 

06030980 6C Chickpea, seed 0.600000 1.000 1.000 

06030981 6C Chickpea, seed-babyfood 0.600000 1.000 1.000 

06030990 6C Chickpea, flour 0.600000 1.000 1.000 

06031820 6C Guar, seed 0.600000 1.000 1.000 

06031821 6C Guar, seed-babyfood 0.600000 1.000 1.000 

06032030 6C Lentil, seed 0.600000 1.000 1.000 

08001480 8 Eggplant 1.500000 1.000 1.000 

08002340 8 Okra 1.500000 1.000 1.000 

08002700 8 Pepper, bell 1.500000 1.000 1.000 

08002701 8 Pepper, bell-babyfood 1.500000 1.000 1.000 

08002710 8 Pepper, bell, dried 1.500000 1.000 1.000 

08002711 8 Pepper, bell, dried-babyfood 1.500000 1.000 1.000 

08002720 8 Pepper, nonbell 1.500000 1.000 1.000 

08002721 8 Pepper, nonbell-babyfood 1.500000 1.000 1.000 

08002730 8 Pepper, nonbell, dried 1.500000 1.000 1.000 

08003740 8 Tomatillo 0.160000 1.000 1.000 

08003750 8 Tomato 0.160000 1.000 1.000 

08003751 8 Tomato-babyfood 0.160000 1.000 1.000 

08003760 8 Tomato, paste 0.160000 1.000 1.000 

08003761 8 Tomato, paste-babyfood 0.160000 1.000 1.000 

08003770 8 Tomato, puree 0.160000 1.000 1.000 

08003771 8 Tomato, puree-babyfood 0.160000 1.000 1.000 

08003780 8 Tomato, dried 0.160000 14.300 1.000 

08003781 8 Tomato, dried-babyfood 0.160000 14.300 1.000 

08003790 8 Tomato, juice 0.160000 1.000 1.000 

09010750 9A Cantaloupe 0.700000 1.000 1.000 

09010800 9A Casaba 0.700000 1.000 1.000 

09011870 9A Honeydew melon 0.700000 1.000 1.000 

09013990 9A Watermelon 0.700000 1.000 1.000 

09014000 9A Watermelon, juice 0.700000 1.000 1.000 

09020210 9B Balsam pear 0.700000 1.000 1.000 

09020880 9B Chayote, fruit 0.700000 1.000 1.000 

09021020 9B Chinese waxgourd 0.700000 1.000 1.000 

09021350 9B Cucumber 0.700000 1.000 1.000 

09023080 9B Pumpkin 0.700000 1.000 1.000 

09023090 9B Pumpkin, seed 0.700000 1.000 1.000 

09023560 9B Squash, summer 0.700000 1.000 1.000 

09023561 9B Squash, summer-babyfood 0.700000 1.000 1.000 

09023570 9B Squash, winter 0.700000 1.000 1.000 

09023571 9B Squash, winter-babyfood 0.700000 1.000 1.000 

10001080 10 Citrus, oil 60.000000 1.000 1.000 

10001990 10 Lemon 0.260000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 17 of 21

10002000 10 Lemon, juice 0.260000 1.000 1.000 

10002001 10 Lemon, juice-babyfood 0.260000 1.000 1.000 

10002010 10 Lemon, peel 0.260000 1.000 1.000 

10002060 10 Lime 0.260000 1.000 1.000 

10002070 10 Lime, juice 0.260000 1.000 1.000 

10002071 10 Lime, juice-babyfood 0.260000 1.000 1.000 

11000070 11 Apple, fruit with peel 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000080 11 Apple, peeled fruit 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000081 11 Apple, peeled fruit-babyfood 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000090 11 Apple, dried 0.500000 8.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000091 11 Apple, dried-babyfood 0.500000 8.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000100 11 Apple, juice 0.500000 1.300 1.000 PP#0F7

 Full comment: PP#0F7696

11000101 11 Apple, juice-babyfood 0.500000 1.300 1.000 PP#0F7

 Full comment: PP#0F7696

11000110 11 Apple, sauce 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11000111 11 Apple, sauce-babyfood 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11001290 11 Crabapple 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002100 11 Loquat 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002660 11 Pear 0.380000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002661 11 Pear-babyfood 0.380000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002670 11 Pear, dried 0.380000 6.250 1.000 PP#0F7

 Full comment: PP#0F7696

11002680 11 Pear, juice 0.380000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11002681 11 Pear, juice-babyfood 0.380000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

11003100 11 Quince 0.500000 1.000 1.000 PP#0F7

 Full comment: PP#0F7696

12000120 12 Apricot 2.000000 1.000 1.000 

12000121 12 Apricot-babyfood 2.000000 1.000 1.000 

12000130 12 Apricot, dried 2.000000 6.000 1.000 

12000140 12 Apricot, juice 2.000000 1.000 1.000 

12000141 12 Apricot, juice-babyfood 2.000000 1.000 1.000 

12000900 12 Cherry 2.000000 1.000 1.000 

12000901 12 Cherry-babyfood 2.000000 1.000 1.000 

12000910 12 Cherry, juice 2.000000 1.500 1.000 

12000911 12 Cherry, juice-babyfood 2.000000 1.500 1.000 

12002300 12 Nectarine 2.000000 1.000 1.000 

12002600 12 Peach 2.000000 1.000 1.000 

12002601 12 Peach-babyfood 2.000000 1.000 1.000 

12002610 12 Peach, dried 2.000000 7.000 1.000 

12002611 12 Peach, dried-babyfood 2.000000 7.000 1.000 

12002620 12 Peach, juice 2.000000 1.000 1.000 

12002621 12 Peach, juice-babyfood 2.000000 1.000 1.000 

12002850 12 Plum 2.000000 1.000 1.000 

12002851 12 Plum-babyfood 2.000000 1.000 1.000 

12002860 12 Plum, prune, fresh 2.000000 1.000 1.000 

12002861 12 Plum, prune, fresh-babyfood 2.000000 1.000 1.000 

12002870 12 Plum, prune, dried 2.000000 5.000 1.000 

12002871 12 Plum, prune, dried-babyfood 2.000000 5.000 1.000 

12002880 12 Plum, prune, juice 2.000000 1.400 1.000 

12002881 12 Plum, prune, juice-babyfood 2.000000 1.400 1.000 

13010550 13A Blackberry 10.000000 1.000 1.000 

13010560 13A Blackberry, juice 10.000000 1.000 1.000 

13010561 13A Blackberry, juice-babyfood 10.000000 1.000 1.000 

13010580 13A Boysenberry 10.000000 1.000 1.000 

13011420 13A Dewberry 10.000000 1.000 1.000 

13012080 13A Loganberry 10.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 18 of 21

13013200 13A Raspberry 10.000000 1.000 1.000 

13013201 13A Raspberry-babyfood 10.000000 1.000 1.000 

13013210 13A Raspberry, juice 10.000000 1.000 1.000 

13013211 13A Raspberry, juice-babyfood 10.000000 1.000 1.000 

13020570 13B Blueberry 3.000000 1.000 1.000 

13020571 13B Blueberry-babyfood 3.000000 1.000 1.000 

13021360 13B Currant 3.000000 1.000 1.000 

13021370 13B Currant, dried 3.000000 1.000 1.000 

13021490 13B Elderberry 3.000000 1.000 1.000 

13021740 13B Gooseberry 3.000000 1.000 1.000 

13021910 13B Huckleberry 3.000000 1.000 1.000 

14000030 14 Almond 0.020000 1.000 1.000 

14000031 14 Almond-babyfood 0.020000 1.000 1.000 

14000040 14 Almond, oil 0.020000 1.000 1.000 

14000041 14 Almond, oil-babyfood 0.020000 1.000 1.000 

14002820 14 Pistachio 0.100000 1.000 1.000 

19010280 19A Basil, fresh leaves 3.000000 1.000 1.000 

19010281 19A Basil, fresh leaves-babyfood 3.000000 1.000 1.000 

19010290 19A Basil, dried leaves 15.000000 1.000 1.000 

19010291 19A Basil, dried leaves-babyfood 15.000000 1.000 1.000 

19011030 19A Chive 3.000000 1.000 1.000 

19011180 19A Coriander, leaves 3.000000 1.000 1.000 

19011181 19A Coriander, leaves-babyfood 3.000000 1.000 1.000 

19011440 19A Dillweed 3.000000 1.000 1.000 

19011840 19A Herbs, other 3.000000 1.000 1.000 

19011841 19A Herbs, other-babyfood 3.000000 1.000 1.000 

19012020 19A Lemongrass 3.000000 1.000 1.000 

19012200 19A Marjoram 3.000000 1.000 1.000 

19012201 19A Marjoram-babyfood 3.000000 1.000 1.000 

19012490 19A Parsley, dried leaves 170.000000 1.000 1.000 

19012491 19A Parsley, dried leaves-babyfood 170.000000 1.000 1.000 

19013340 19A Savory 3.000000 1.000 1.000 

20003190 20 Rapeseed, oil 0.030000 1.000 1.000 

20003191 20 Rapeseed, oil-babyfood 0.030000 1.000 1.000 

21000460 M Beef, meat byproducts 0.020000 1.000 1.000 

21000461 M Beef, meat byproducts-babyfood 0.020000 1.000 1.000 

21000480 M Beef, kidney 0.020000 1.000 1.000 

21000490 M Beef, liver 0.020000 1.000 1.000 

21000491 M Beef, liver-babyfood 0.020000 1.000 1.000 

23001700 M Goat, meat byproducts 0.020000 1.000 1.000 

23001720 M Goat, kidney 0.020000 1.000 1.000 

23001730 M Goat, liver 0.020000 1.000 1.000 

26003400 M Sheep, meat byproducts 0.020000 1.000 1.000 

26003420 M Sheep, kidney 0.020000 1.000 1.000 

26003430 M Sheep, liver 0.020000 1.000 1.000 

86010000 O Water, direct, all sources 0.024650 1.000 1.000 

86020000 O Water, indirect, all sources 0.024650 1.000 1.000 

95000200 O Avocado 1.200000 1.000 1.000 

95000740 O Canistel 1.200000 1.000 1.000 

95001750 O Grape 0.810000 1.000 1.000 

95001760 O Grape, juice 0.810000 1.200 1.000 

95001761 O Grape, juice-babyfood 0.810000 1.200 1.000 

95001770 O Grape, leaves 0.810000 1.000 1.000 

95001780 O Grape, raisin 3.000000 1.000 1.000 

95001790 O Grape, wine and sherry 0.810000 1.000 1.000 

95001950 O Kiwifruit 1.800000 1.000 1.000 

95002090 O Longan 2.000000 1.000 1.000 

95002110 O Lychee 2.000000 1.000 1.000 

95002120 O Lychee, dried 2.000000 1.850 1.000 

95002150 O Mango 1.200000 1.000 1.000 

95002151 O Mango-babyfood 1.200000 1.000 1.000 

95002160 O Mango, dried 1.200000 1.000 1.000 

95002170 O Mango, juice 1.200000 1.000 1.000 

95002171 O Mango, juice-babyfood 1.200000 1.000 1.000 

95002450 O Papaya 1.200000 1.000 1.000 

95002451 O Papaya-babyfood 1.200000 1.000 1.000 

95002460 O Papaya, dried 1.200000 1.800 1.000 

95002470 O Papaya, juice 1.200000 1.500 1.000 

95003330 O Sapote, Mamey 1.200000 1.000 1.000 

95003510 O Spanish lime 2.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 19 of 21

95003590 O Strawberry 5.000000 1.000 1.000 

95003591 O Strawberry-babyfood 5.000000 1.000 1.000 

95003600 O Strawberry, juice 5.000000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 5.000000 1.000 1.000 

95003980 O Watercress 20.000000 1.000 1.000 
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 20 of 21

Attachment 3 Results of Acute DEEM-FCID Dietary Exposure Analysis

U.S. Environmental Protection Agency Ver. 2.02

DEEM-FCID ACUTE Analysis for CYPRODINIL (1994-98 data)

Residue file: 288202acuteEPArecommendations.R98 Adjustment factor #2 used.

Analysis Date: 03-22-2012/07:11:33 Residue file dated: 03-22-2012/07:08:52/8

Daily totals for food and foodform consumption used.

Run Comment: ""

===============================================================================

Summary calculations (per capita):

 95th Percentile 99th Percentile 99.9th Percentile

 Exposure % aRfD Exposure % aRfD Exposure % aRfD 

 ---------- -------- ---------- -------- ---------- --------

U.S. Population:

 0.095794 4.79 0.173478 8.67 0.327751 16.39 

All infants:

 0.102882 5.14 0.372488 18.62 0.943947 47.20 

Children 1-2 yrs:

 0.151445 7.57 0.288151 14.41 0.744868 37.24 

Children 3-5 yrs:

 0.131883 6.59 0.241040 12.05 0.536255 26.81 

Children 6-12 yrs:

 0.098193 4.91 0.167538 8.38 0.358174 17.91 

Youth 13-19 yrs:

 0.080270 4.01 0.160028 8.00 0.212343 10.62 

Adults 20-49 yrs:

 0.092162 4.61 0.172228 8.61 0.309780 15.49 

Adults 50+ yrs:

 0.085400 4.27 0.155374 7.77 0.264973 13.25 

Females 13-49 yrs:

 0.099465 4.97 0.174098 8.70 0.309890 15.49
Cyprodinil (PC Code 288202) Dietary Exposure and Risk Assessment DP # 390233 & 398362: 

Page 21 of 21

Attachment 4 Results of Chronic DEEM-FCID Dietary Exposure Analysis

U.S. Environmental Protection Agency Ver. 2.00

DEEM-FCID Chronic analysis for CYPRODINIL (1994-98 data)

Residue file name: C:\Documents and Settings\tmorton\My Documents\MyFiles\DEEM Files\288202 

Cyprodinil\Leafy Petioles 1E7869 and Misc 1E7854\288202chronicEPArecommendations.R98

 Adjustment factor #2 used.

Analysis Date 03-22-2012/07:13:12 Residue file dated: 03-22-2012/07:09:53/8

Reference dose (RfD, Chronic) = .027 mg/kg bw/day

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ---------------

U.S. Population (total) 0.007421 27.5%

U.S. Population (spring season) 0.007725 28.6%

U.S. Population (summer season) 0.007667 28.4%

U.S. Population (autumn season) 0.007106 26.3%

U.S. Population (winter season) 0.007194 26.6%

Northeast region 0.007971 29.5%

Midwest region 0.007167 26.5%

Southern region 0.006476 24.0%

Western region 0.008696 32.2%

Hispanics 0.007440 27.6%

Non-hispanic whites 0.007328 27.1%

Non-hispanic blacks 0.006939 25.7%

Non-hisp/non-white/non-black 0.010253 38.0%

All infants (< 1 year) 0.014099 52.2%

Nursing infants 0.007361 27.3%

Non-nursing infants 0.016657 61.7%

Children 1-6 yrs 0.016210 60.0%

Children 7-12 yrs 0.008060 29.9%

Females 13-19 (not preg or nursing) 0.005111 18.9%

Females 20+ (not preg or nursing) 0.006767 25.1%

Females 13-50 yrs 0.006317 23.4%

Females 13+ (preg/not nursing) 0.006768 25.1%

Females 13+ (nursing) 0.007128 26.4%

Males 13-19 yrs 0.005276 19.5%

Males 20+ yrs 0.005869 21.7%

Seniors 55+ 0.007358 27.3%

Children 1-2 yrs 0.020269 75.1%

Children 3-5 yrs 0.015148 56.1%

Children 6-12 yrs 0.008552 31.7%

Youth 13-19 yrs 0.005195 19.2%

Adults 20-49 yrs 0.005818 21.5%

Adults 50+ yrs 0.007260 26.9%

Females 13-49 yrs 0.006066 22.5%

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