Exhibit 10.22

CONFIDENTIAL TREATMENT REQUESTED BY REGENERATION TECHNOLOGIES, INC. FOR CERTAIN PORTIONS OF THIS AGREEMENT IN ACCORDANCE WITH RULE 24B-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED

SECOND AMENDMENT TO FIRST AMENDED EXCLUSIVE

DISTRIBUTION AND LICENSE AGREEMENT

THIS SECOND AMENDMENT TO FIRST AMENDED EXCLUSIVE DISTRIBUTION AND LICENSE AGREEMENT
(this Amendment) is made and entered into as of December 15, 2005 by and between Regeneration Technologies, Inc., a Delaware corporation (RTI), and Medtronic Sofamor Danek USA, Inc., a Tennessee corporation
(MSD).

WITNESSETH:

WHEREAS, MSD and RTI are parties to a First Amended Exclusive Distribution and License Agreement having an effective date of April 15, 2004, and parties to a First Amendment to First Amended Exclusive
Distribution and License Agreement having an effective date of March 1, 2005 (collectively, the Agreement).

WHEREAS, MSD
and RTI desire to amend the Agreement on the terms and conditions set forth herein;

AGREEMENT

NOW THEREFORE, in consideration of the representations, warranties, covenants and agreements contained herein, and for other valuable consideration, the
receipt and adequacy of which is hereby acknowledged, the parties mutually agree as follows:

1. Definitions. Capitalized terms used
herein and not otherwise defined herein shall have the meanings set forth in the Agreement.

2. Amendments.

(a) Schedule 2.1. Schedule 2.1 of the Agreement is hereby amended and restated to read in its entirety in the form attached hereto as Attachment A.

(b) Minimum Volume Commitment. The fees set forth in the Column B entitled LSF Effective 7/1/2005 on Schedule 2.1 shall
be effective on the date this Second Amendment is signed by both parties and apply retroactive to July 1, 2005. The fees in Column B relative to Cornerstone SR and Cornerstone Pinnacle/Cornerstone Lordotic Pinnacle shall be remain effective
provided that RTI produces and delivers to MSD the minimum monthly quantities of specialty allografts indicated below, subject to receipt by RTI of Binding Forecasts from MSD in those amounts or greater during the relevant month.



|                              |  |                           
|----------------------------- |  | --------------------------
|                              |  | Minimum Monthly Quantities
|Cornerstone SR (mono only)    |  | [***]/month               
|Cornerstone Pinnacle/         |  | [***]/month               
|Cornerstone Lordotic Pinnacle |  |                           



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|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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If RTI fails to produce and deliver to MSD the indicated Minimum Monthly Quantities of Cornerstone SR or
Cornerstone Pinnacle/Cornerstone Lordotic Pinnacle allografts for any two (2) months during a particular calendar quarter, subject to receipt by RTI of Binding Forecasts from MSD in those amounts or greater during the relevant month, then the
fees for Cornerstone SR and Cornerstone Pinnacle/Cornerstone Lordotic Pinnacle allografts for that quarter only shall thereafter shall revert back to that indicated in Column A entitled LSF through June 30, 2005 on Schedule 2.1.

Fees for the Cornerstone SR and Cornerstone Pinnacle/Cornerstone Lordotic Pinnacle allografts in subsequent quarters shall be in
accordance with Column B fees provided RTI supplies the Minimum Monthly Quantities for at least two (2) of the months in the subsequent calendar quarter, subject to receipt by RTI of Binding Forecasts from MSD in those amounts or greater.

RTI shall not be responsible for producing and delivering the Minimum Monthly Quantities specified herein for a particular month to the
extent that, during that month, the percentage of allografts orders for Cornerstone SR (mono only) and Cornerstone Pinnacle/Cornerstone Lordotic Pinnacle in the range of [***]mm through [***]mm in size is greater than [***]% of the total number of
allografts constituting the Minimum Monthly Quantity for that month.

3. Acknowledgement and Agreement. The parties acknowledge that
the binding orders for Specialty Allografts and Bone Paste indicated in Attachment B attached hereto were placed by MSD in December 2004. The parties acknowledge and agree that, for purposes of calculating the exclusivity provision set forth in
Section 3.1(d) of the Agreement, [***] percent ([***]%) of such orders shall be treated as having been placed in the first quarter of 2005 and [***] percent ([***]%) of such orders shall be treated as having been placed in the second quarter of
2005.

4. Ratification. Except as amended hereby, the Agreement is hereby ratified and confirmed in all respects. As amended hereby,
the Agreement shall be read and construed as one and the same instrument.

[THE REMAINDER OF THIS PAGE IS INTENTIONALLY BLANK.]

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|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
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|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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IN WITNESS WHEREOF, each of the parties has caused this Second Amendment to the First Amended Exclusive
Distribution and License Agreement to be executed by their respective duly authorized representatives as of the date first above written.



REGENERATION TECHNOLOGIES, INC.By:

/s/ Roger W. RoseIts:

Executive Vice PresidentMEDTRONIC SOFAMOR DANEK USA, INC.By:

/s/ Peter L. WehrlyIts:

President Medtronic Sofamor Danek




---

Attachment A to Second Amendment to First Amendment to First Amended Exclusive License and

Distribution Agreement

Amended
Schedule 2.1

Effective December 2005

EXCLUSIVE



|                                                      |  |                                                      |  |                                |  |                                
|----------------------------------------------------- |  | ---------------------------------------------------- |  | ------------------------------ |  | -------------------------------
|Product Code                                          |  | Description                                          |  | Column A LSF through 6/30/2005 |  | Column B LSF Effective 7/1/2005
|Cornerstone L-SR (Lordotic SR Cortical Block)         |  |                                                      |  |                               
|300511                                                |  | Cornerstone Lordotic SR Cortical Block 5 x 11 x 11mm |  | [***]                          |  | [***]                          
|300541                                                |  | Cornerstone Lordotic SR Cortical Block 5 x 14 x 11mm |  | [***]                          |  | [***]                          
|300544                                                |  | Cornerstone Lordotic SR Cortical Block 5 x 14 x 14mm |  | [***]                          |  | [***]                          
|300611                                                |  | Cornerstone Lordotic SR Cortical Block 6 x 11 x 11mm |  | [***]                          |  | [***]                          
|300641                                                |  | Cornerstone Lordotic SR Cortical Block 6 x 14 x 11mm |  | [***]                          |  | [***]                          
|300644                                                |  | Cornerstone Lordotic SR Cortical Block 6 x 14 x 14mm |  | [***]                          |  | [***]                          
|300711                                                |  | Cornerstone Lordotic SR Cortical Block 7 x 11 x 11mm |  | [***]                          |  | [***]                          
|300741                                                |  | Cornerstone Lordotic SR Cortical Block 7 x 14 x 11mm |  | [***]                          |  | [***]                          
|300744                                                |  | Cornerstone Lordotic SR Cortical Block 7 x 14 x 14mm |  | [***]                          |  | [***]                          
|300811                                                |  | Cornerstone Lordotic SR Cortical Block 8 x 11 x 11mm |  | [***]                          |  | [***]                          
|300841                                                |  | Cornerstone Lordotic SR Cortical Block 8 x 14 x 11mm |  | [***]                          |  | [***]                          
|300844                                                |  | Cornerstone Lordotic SR Cortical Block 8 x 14 x 14mm |  | [***]                          |  | [***]                          
|300911                                                |  | Cornerstone Lordotic SR Cortical Block 9 x 11 x 11mm |  | [***]                          |  | [***]                          
|300941                                                |  | Cornerstone Lordotic SR Cortical Block 9 x 14 x 11mm |  | [***]                          |  | [***]                          
|300944                                                |  | Cornerstone Lordotic SR Cortical Block 9 x 14 x 14mm |  | [***]                          |  | [***]                          
|                                                      |  |                                                     
|Cornerstone SR (SR Cortical Block)                    |  |                                                      |  |                               
|200511                                                |  | Cornerstone SR Cortical Block 5 x 11 x 11mm          |  | [***]                          |  | [***]                          
|200541                                                |  | Cornerstone SR Cortical Block 5 x 14 x 11mm          |  | [***]                          |  | [***]                          
|200544                                                |  | Cornerstone SR Cortical Block 5 x 14 x 14mm          |  | [***]                          |  | [***]                          
|200611                                                |  | Cornerstone SR Cortical Block 6 x 11 x 11mm          |  | [***]                          |  | [***]                          
|200641                                                |  | Cornerstone SR Cortical Block 6 x 14 x 11mm          |  | [***]                          |  | [***]                          
|200644                                                |  | Cornerstone SR Cortical Block 6 x 14 x 14mm          |  | [***]                          |  | [***]                          
|200711                                                |  | Cornerstone SR Cortical Block 7 x 11 x 11mm          |  | [***]                          |  | [***]                          
|200741                                                |  | Cornerstone SR Cortical Block 7 x 14 x 11mm          |  | [***]                          |  | [***]                          
|200744                                                |  | Cornerstone SR Cortical Block 7 x 14 x 14mm          |  | [***]                          |  | [***]                          
|200811                                                |  | Cornerstone SR Cortical Block 8 x 11 x 11mm          |  | [***]                          |  | [***]                          
|200841                                                |  | Cornerstone SR Cortical Block 8 x 14 x 11mm          |  | [***]                          |  | [***]                          
|200844                                                |  | Cornerstone SR Cortical Block 8 x 14 x 14mm          |  | [***]                          |  | [***]                          
|200911                                                |  | Cornerstone SR Cortical Block 9 x 11 x 11mm          |  | [***]                          |  | [***]                          
|200941                                                |  | Cornerstone SR Cortical Block 9 x 14 x 11mm          |  | [***]                          |  | [***]                          
|200944                                                |  | Cornerstone SR Cortical Block 9 x 14 x 14mm          |  | [***]                          |  | [***]                          
|201041                                                |  | Cornerstone SR Cortical Block 10 x 14 x 11mm         |  | [***]                          |  | [***]                          
|201141                                                |  | Cornerstone SR Cortical Block 11 x 14 x 11mm         |  | [***]                          |  | [***]                          
|201241                                                |  | Cornerstone SR Cortical Block 12 x 14 x 11mm         |  | [***]                          |  | [***]                          
|                                                      |  |                                                     
|Cornerstone ASR (Composite cortical-Cancellous Block) |  |                                                      |  |                               
|245041                                                |  | ASR Cortical-Cancellous Block 10 x 14 x 11mm         |  | [***]                          |  | [***]                          
|245141                                                |  | ASR Cortical-Cancellous Block 11 x 14 x 12mm         |  | [***]                          |  | [***]                          
|245241                                                |  | ASR Cortical-Cancellous Block 12 x 14 x 11mm         |  | [***]                          |  | [***]                          
|245341                                                |  | ASR Cortical-Cancellous Block 13 x 14 x 11mm         |  | [***]                          |  | [***]                          
|245741                                                |  | ASR Cortical-Cancellous Block 7 x 14 x 11mm          |  | [***]                          |  | [***]                          
|245841                                                |  | ASR Cortical-Cancellous Block 8 x 14 x 11mm          |  | [***]                          |  | [***]                          
|245941                                                |  | ASR Cortical-Cancellous Block 9 x 14 x 11mm          |  | [***]                          |  | [***]                          

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



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|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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EXCLUSIVE



|                                                                |  |                                                       |  |                                |  |                                
|--------------------------------------------------------------- |  | ----------------------------------------------------- |  | ------------------------------ |  | -------------------------------
|Product Code                                                    |  | Description                                           |  | Column A LSF through 6/30/2005 |  | Column B LSF Effective 7/1/2005
|Cornerstone LASR (Lordotic Composite Cortical-Cancellous Block) |  |                                                       |  |                               
|345011                                                          |  | Lordotic ASR Cortical-Cancellous Block 10 x 11 x 11mm |  | [***]                          |  | [***]                          
|345041                                                          |  | Lordotic ASR Cortical-Cancellous Block 10 x 14 x 11mm |  | [***]                          |  | [***]                          
|345044                                                          |  | Lordotic ASR Cortical-Cancellous Block 10 x 14 x 14mm |  | [***]                          |  | [***]                          
|345111                                                          |  | Lordotic ASR Cortical-Cancellous Block 11 x 11 x 11mm |  | [***]                          |  | [***]                          
|345141                                                          |  | Lordotic ASR Cortical-Cancellous Block 11 x 14 x 11mm |  | [***]                          |  | [***]                          
|345144                                                          |  | Lordotic ASR Cortical-Cancellous Block 11 x 14 x 14mm |  | [***]                          |  | [***]                          
|345211                                                          |  | Lordotic ASR Cortical-Cancellous Block 12 x 11 x 11mm |  | [***]                          |  | [***]                          
|345241                                                          |  | Lordotic ASR Cortical-Cancellous Block 12 x 14 x 11mm |  | [***]                          |  | [***]                          
|345244                                                          |  | Lordotic ASR Cortical-Cancellous Block 12 x 14 x 14mm |  | [***]                          |  | [***]                          
|345711                                                          |  | Lordotic ASR Cortical-Cancellous Block 7 x 11 x 11mm  |  | [***]                          |  | [***]                          
|345741                                                          |  | Lordotic ASR Cortical-Cancellous Block 7 x 14 x 11mm  |  | [***]                          |  | [***]                          
|345744                                                          |  | Lordotic ASR Cortical-Cancellous Block 7 x 14 x 14mm  |  | [***]                          |  | [***]                          
|345811                                                          |  | Lordotic ASR Cortical-Cancellous Block 8 x 11 x 11mm  |  | [***]                          |  | [***]                          
|345841                                                          |  | Lordotic ASR Cortical-Cancellous Block 8 x 14 x 11mm  |  | [***]                          |  | [***]                          
|345844                                                          |  | Lordotic ASR Cortical-Cancellous Block 8 x 14 x 14mm  |  | [***]                          |  | [***]                          
|245911                                                          |  | Lordotic ASR Cortical-Cancellous Block 9 x 11 x 11mm  |  | [***]                          |  | [***]                          
|345941                                                          |  | Lordotic ASR Cortical-Cancellous Block 9 x 14 x 11mm  |  | [***]                          |  | [***]                          
|345944                                                          |  | Lordotic ASR Cortical-Cancellous Block 9 x 14 x 14mm  |  | [***]                          |  | [***]                          
|                                                                |  |                                                      
|Cornerstone Pinnacle                                            |  |                                                       |  |                               
|545541                                                          |  | Cornerstone Pinnacle 5 x 14 x 11                      |  | [***]                          |  | [***]                          
|545641                                                          |  | Cornerstone Pinnacle 6 x 14 x 11                      |  | [***]                          |  | [***]                          
|                                                                |  |                                                       |  | [***]                          |  |                                
|                                                                |  |                                                      
|Cornerstone Lordotic MASR Pinnacle                              |  |                                                       |  | [***]                         
|645611                                                          |  | Lordotic MASR Cortical-Cancellous Block 6 x 11 x 11mm |  | [***]                          |  | [***]                          
|645641                                                          |  | Lordotic MASR Cortical-Cancellous Block 6 x 14 x 11mm |  | [***]                          |  | [***]                          
|645644                                                          |  | Lordotic MASR Cortical-Cancellous Block 6 x 14 x 14mm |  | [***]                          |  | [***]                          
|645511                                                          |  | Lordotic MASR Cortical-Cancellous Block 5 x 11 x 11mm |  | [***]                          |  | [***]                          
|645541                                                          |  | Lordotic MASR Cortical-Cancellous Block 5 x 14 x 11mm |  | [***]                          |  | [***]                          
|645544                                                          |  | Lordotic MASR Cortical-Cancellous Block 5 x 14 x 14mm |  | [***]                          |  | [***]                          
|                                                                |  |                                                      
|Cornerstone Reserve (Cortical-Cancellous Ring)                  |  |                                                       |  |                               
|270050                                                          |  | Cortical Ring w/ Cancellous Plug 5mm                  |  | [***]                          |  | [***]                          
|270060                                                          |  | Cortical Ring w/ Cancellous Plug 6mm                  |  | [***]                          |  | [***]                          
|270070                                                          |  | Cortical Ring w/ Cancellous Plug 7mm                  |  | [***]                          |  | [***]                          
|270080                                                          |  | Cortical Ring w/ Cancellous Plug 8mm                  |  | [***]                          |  | [***]                          
|270090                                                          |  | Cortical Ring w/ Cancellous Plug 9mm                  |  | [***]                          |  | [***]                          
|270100                                                          |  | Cortical Ring w/ Cancellous Plug 10mm                 |  | [***]                          |  | [***]                          
|270110                                                          |  | Cortical Ring w/ Cancellous Plug 11mm                 |  | [***]                          |  | [***]                          
|270120                                                          |  | Cortical Ring w/ Cancellous Plug 12mm                 |  | [***]                          |  | [***]                          
|270130                                                          |  | Cortical Ring w/ Cancellous Plug 13mm                 |  | [***]                          |  | [***]                          

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



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|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



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EXCLUSIVE



|                                     |  |                                      |  |                                |  |                                
|------------------------------------ |  | ------------------------------------ |  | ------------------------------ |  | -------------------------------
|Product Code                         |  | Description                          |  | Column A LSF through 6/30/2005 |  | Column B LSF Effective 7/1/2005
|Cornerstone Select (Fibula Wedge)    |  |                                      |  |                               
|210500                               |  | Cornerstone Select 5mm               |  | [***]                          |  | [***]                          
|210600                               |  | Cornerstone Select 6mm               |  | [***]                          |  | [***]                          
|210700                               |  | Cornerstone Select 7mm               |  | [***]                          |  | [***]                          
|210800                               |  | Cornerstone Select 8mm               |  | [***]                          |  | [***]                          
|210900                               |  | Cornerstone Select 9mm               |  | [***]                          |  | [***]                          
|211000                               |  | Cornerstone Select 10mm              |  | [***]                          |  | [***]                          
|211100                               |  | Cornerstone Select 11mm              |  | [***]                          |  | [***]                          
|211200                               |  | Cornerstone Select 12mm              |  | [***]                          |  | [***]                          
|211300                               |  | Cornerstone Select 13mm              |  | [***]                          |  | [***]                          
|213500                               |  | Cornerstone Select 35mm              |  | [***]                          |  | [***]                          
|215000                               |  | Cornerstone Select 50mm              |  | [***]                          |  | [***]                          
|217000                               |  | Cornerstone Select 70mm              |  | [***]                          |  | [***]                          
|                                     |  |                                     
|Humeral Ring                         |  |                                      |  |                               
|692017                               |  | Humeral Ring                         |  | [***]                          |  | [***]                          
|                                     |  |                                     
|Unicortical Dowel                    |  |                                      |  |                               
|280012                               |  | Unicortical Dowel 12mm               |  | [***]                          |  | [***]                          
|280014                               |  | Unicortical Dowel 14mm               |  | [***]                          |  | [***]                          
|280016                               |  | Unicortical Dowel 16mm               |  | [***]                          |  | [***]                          
|                                     |  |                                     
|Cornerstone Iliac Block, Tricortical |  |                                      |  |                               
|310107                               |  | Iliac Block, Tricortical 7mm x 15mm  |  | [***]                          |  | [***]                          
|310108                               |  | Iliac Block, Tricortical 8mm x 15mm  |  | [***]                          |  | [***]                          
|310109                               |  | Iliac Block, Tricortical 9mm x 15mm  |  | [***]                          |  | [***]                          
|310110                               |  | Iliac Block, Tricortical 10mm x 15mm |  | [***]                          |  | [***]                          
|310112                               |  | Iliac Block, Tricortical 12mm x 15mm |  | [***]                          |  | [***]                          
|310114                               |  | Iliac Block, Tricortical 14mm x 15mm |  | [***]                          |  | [***]                          
|310115                               |  | Iliac Block, Tricortical 15mm x 15mm |  | [***]                          |  | [***]                          
|310116                               |  | Iliac Block, Tricortical 16mm x 15mm |  | [***]                          |  | [***]                          
|310118                               |  | Iliac Block, Tricortical 18mm x 15mm |  | [***]                          |  | [***]                          
|310120                               |  | Iliac Block, Tricortical 20mm x 15mm |  | [***]                          |  | [***]                          
|310225                               |  | Iliac Block, Tricortical 25mm x 15mm |  | [***]                          |  | [***]                          
|                                     |  |                                     
|Cornerstone Unicortical Block        |  |                                      |  |                               
|850612                               |  | Unicortical Block 6 x 12mm           |  | [***]                          |  | [***]                          
|850712                               |  | Unicortical Block 7 x 12mm           |  | [***]                          |  | [***]                          
|850812                               |  | Unicortical Block 8 x 12mm           |  | [***]                          |  | [***]                          
|850912                               |  | Unicortical Block 9 x 12mm           |  | [***]                          |  | [***]                          

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



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|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

EXCLUSIVE



|                           |  |                                                   |  |                                |  |                                
|-------------------------- |  | ------------------------------------------------- |  | ------------------------------ |  | -------------------------------
|Product Code               |  | Description                                       |  | Column A LSF through 6/30/2005 |  | Column B LSF Effective 7/1/2005
|Tangent                    |  |                                                   |  |                               
|160820                     |  | Tangent Impacted Wedge FZ 8 x 20                  |  | [***]                          |  | [***]                          
|161020                     |  | Tangent Impacted Wedge FZ 10 x 20                 |  | [***]                          |  | [***]                          
|161220                     |  | Tangent Impacted Wedge FZ 12 x 20                 |  | [***]                          |  | [***]                          
|160826                     |  | Tangent Impacted Wedge FZ 8 x 26                  |  | [***]                          |  | [***]                          
|161026                     |  | Tangent Impacted Wedge FZ 10 x 26                 |  | [***]                          |  | [***]                          
|161226                     |  | Tangent Impacted Wedge FZ 12 x 26                 |  | [***]                          |  | [***]                          
|161426                     |  | Tangent Impacted Wedge FZ 14 x 26                 |  | [***]                          |  | [***]                          
|170820                     |  | Tangent Impacted Wedge FZD 8 x 20                 |  | [***]                          |  | [***]                          
|170826                     |  | Tangent Impacted Wedge FZD 8 x 26                 |  | [***]                          |  | [***]                          
|171020                     |  | Tangent Impacted Wedge FZD 10 x 20                |  | [***]                          |  | [***]                          
|171026                     |  | Tangent Impacted Wedge FZD 10 x 26                |  | [***]                          |  | [***]                          
|171220                     |  | Tangent Impacted Wedge FZD 12 x 20                |  | [***]                          |  | [***]                          
|171226                     |  | Tangent Impacted Wedge FZD 12 x 26                |  | [***]                          |  | [***]                          
|171426                     |  | Tangent Impacted Wedge FZD 14 x 26                |  | [***]                          |  | [***]                          
|171626                     |  | Tangent Impacted Wedge FZD 16 x 26                |  | [***]                          |  | [***]                          
|                           |  |                                                  
|Cancellous Block           |  |                                                   |  |                               
|260130                     |  | Cancellous Block 13-17(H) x 13-17(W) x 20-60(L)mm |  | [***]                          |  | [***]                          
|260230                     |  | Cancellous Block 18-22(H) x 18-22(W) x 20-60(L)mm |  | [***]                          |  | [***]                          
|260330                     |  | Cancellous Block 23-27(H) x 23-27(W) x 20-60(L)mm |  | [***]                          |  | [***]                          
|                           |  |                                                  
|Patellar Tricortical Wedge |  |                                                   |  |                               
|340015                     |  | Patellar Tricortical Wedge 15(H) x 25(L)mm        |  | [***]                          |  | [***]                          
|340018                     |  | Patellar Tricortical Wedge 18(H) x 25(L)mm        |  | [***]                          |  | [***]                          
|340020                     |  | Patellar Tricortical Wedge 20(H) x 25(L)mm        |  | [***]                          |  | [***]                          
|                           |  |                                                  
|Fibular Ring               |  |                                                   |  |                               
|661106                     |  | Fibular Ring 6mm                                  |  | [***]                          |  | [***]                          
|661107                     |  | Fibular Ring 7mm                                  |  | [***]                          |  | [***]                          
|661108                     |  | Fibular Ring 8mm                                  |  | [***]                          |  | [***]                          
|661109                     |  | Fibular Ring 9mm                                  |  | [***]                          |  | [***]                          
|661110                     |  | Fibular Ring 10mm                                 |  | [***]                          |  | [***]                          
|                           |  |                                                  
|Bicortical Block           |  |                                                   |  |                               
|862010                     |  | Bi-Cortical Block 10mm x 20mm                     |  | [***]                          |  | [***]                          
|862012                     |  | Bi-Cortical Block 12mm x 20mm                     |  | [***]                          |  | [***]                          
|862014                     |  | Bi-Cortical Block 14mm x 20mm                     |  | [***]                          |  | [***]                          
|862512                     |  | Bi-Cortical Block 12mm x 25mm                     |  | [***]                          |  | [***]                          
|862514                     |  | Bi-Cortical Block 14mm x 25mm                     |  | [***]                          |  | [***]                          
|862516                     |  | Bi-Cortical Block 16mm x 25mm                     |  | [***]                          |  | [***]                          
|872007                     |  | Bi-Cortical Block 7mm                             |  | [***]                          |  | [***]                          
|872008                     |  | Bi-Cortical Block 8mm                             |  | [***]                          |  | [***]                          
|872009                     |  | Bi-Cortical Block 9mm                             |  | [***]                          |  | [***]                          
|872010                     |  | Bi-Cortical Block 10mm                            |  | [***]                          |  | [***]                          

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

EXCLUSIVE



|                                         |  |                                               |  |                                |  |                                
|---------------------------------------- |  | --------------------------------------------- |  | ------------------------------ |  | -------------------------------
|Product Code                             |  | Description                                   |  | Column A LSF through 6/30/2005 |  | Column B LSF Effective 7/1/2005
|Tricortical Block                        |  |                                               |  |                               
|320105                                   |  | Tricortical Block 5mm                         |  | [***]                          |  | [***]                          
|320106                                   |  | Tricortical Block 6mm                         |  | [***]                          |  | [***]                          
|320107                                   |  | Tricortical Block 7mm                         |  | [***]                          |  | [***]                          
|320108                                   |  | Tricortical Block 8mm                         |  | [***]                          |  | [***]                          
|320109                                   |  | Tricortical Block 9mm                         |  | [***]                          |  | [***]                          
|320110                                   |  | Tricortical Block 10mm                        |  | [***]                          |  | [***]                          
|                                         |  |                                              
|Freeze-Dried Precision Graft             |  |                                               |  |                               
|439012                                   |  | FZD Machined Cortical Ring 12 x 26 x 26mm     |  | [***]                          |  | [***]                          
|439014                                   |  | FZD Machined Cortical Ring 14 x 26 x 26mm     |  | [***]                          |  | [***]                          
|439016                                   |  | FZD Machined Cortical Ring 16 x 26 x 26mm     |  | [***]                          |  | [***]                          
|439018                                   |  | FZD Machined Cortical Ring 18 x 26 x 26mm     |  | [***]                          |  | [***]                          
|439020                                   |  | FZD Machined Cortical Ring 20 x 26 x 26mm     |  | [***]                          |  | [***]                          
|                                         |  |                                              
|Frozen Precision Graft                   |  |                                               |  |                               
|451066                                   |  | Precision Impacted Cortical ring 10 x 26 x 26 |  | [***]                          |  | [***]                          
|451244                                   |  | Precision Impacted Cortical ring 12 x 24 x 24 |  | [***]                          |  | [***]                          
|451266                                   |  | Precision Impacted Cortical ring 12 x 26 x 26 |  | [***]                          |  | [***]                          
|451444                                   |  | Precision Impacted Cortical ring 14 x 24 x 24 |  | [***]                          |  | [***]                          
|451466                                   |  | Precision Impacted Cortical ring 14 x 26 x 26 |  | [***]                          |  | [***]                          
|451644                                   |  | Precision Impacted Cortical ring 16 x 24 x 24 |  | [***]                          |  | [***]                          
|451666                                   |  | Precision Impacted Cortical ring 16 x 26 x 26 |  | [***]                          |  | [***]                          
|451844                                   |  | Precision Impacted Cortical ring 18 x 24 x 24 |  | [***]                          |  | [***]                          
|451866                                   |  | Precision Impacted Cortical ring 18 x 26 x 26 |  | [***]                          |  | [***]                          
|452044                                   |  | Precision Impacted Cortical ring 20 x 24 x 24 |  | [***]                          |  | [***]                          
|452066                                   |  | Precision Impacted Cortical ring 20 x 26 x 26 |  | [***]                          |  | [***]                          
|452466                                   |  | Precision Impacted Cortical ring 24 x 26 x 26 |  | [***]                          |  | [***]                          
|                                         |  |                                              
|Assembled ALIF                           |  |                                               |  |                               
|939012                                   |  | Precision Plus 12mm                           |  | [***]                          |  | [***]                          
|939014                                   |  | Precision Plus 14mm                           |  | [***]                          |  | [***]                          
|939016                                   |  | Precision Plus 16mm                           |  | [***]                          |  | [***]                          
|939018                                   |  | Precision Plus 18mm                           |  | [***]                          |  | [***]                          
|939020                                   |  | Precision Plus 20mm                           |  | [***]                          |  | [***]                          
|                                         |  |                                              
|MDII Threaded Cortical Bone Dowel Frozen |  |                                               |  |                               
|401114                                   |  | MDII Threaded Dowel 14 x 20mm                 |  | [***]                          |  | [***]                          
|401116                                   |  | MDII Threaded Dowel 16 x 20mm                 |  | [***]                          |  | [***]                          
|401118                                   |  | MDII Threaded Dowel 18 x 20mm                 |  | [***]                          |  | [***]                          
|401120                                   |  | MDII Threaded Dowel 20 x 20mm                 |  | [***]                          |  | [***]                          
|401214                                   |  | MDII Threaded Dowel 14 x 23mm                 |  | [***]                          |  | [***]                          
|401216                                   |  | MDII Threaded Dowel 16 x 23mm                 |  | [***]                          |  | [***]                          
|401218                                   |  | MDII Threaded Dowel 18 x 23mm                 |  | [***]                          |  | [***]                          
|401220                                   |  | MDII Threaded Dowel 20 x 23mm                 |  | [***]                          |  | [***]                          
|401316                                   |  | MDII Threaded Dowel 16 x 26mm                 |  | [***]                          |  | [***]                          
|401318                                   |  | MDII Threaded Dowel 18 x 26mm                 |  | [***]                          |  | [***]                          
|401320                                   |  | MDII Threaded Dowel 20 x 26mm                 |  | [***]                          |  | [***]                          
|401222                                   |  | MDII Threaded Dowel 22 x 23mm                 |  | [***]                          |  | [***]                          

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

EXCLUSIVE



|                                         |  |                               |  |                                |  |                               
|---------------------------------------- |  | ----------------------------- |  | ------------------------------ |  | ------------------------------
|Product Code                             |  | Description                   |  | Column A LSF through 6/30/2005 |  | Column B LSF Effective7/1/2005
|MDII Threaded Cortical Bone Dowel Frozen |  |                               |  |                               
|401224                                   |  | MDII Threaded Dowel 24 x 23mm |  | [***]                          |  | [***]                         
|401322                                   |  | MDII Threaded Dowel 22 x 26mm |  | [***]                          |  | [***]                         
|                                         |  |                              
|MDIV Threaded Cortical Bone              |  |                               |  |                               
|441218                                   |  | MDIV Threaded Dowel 18 x 23mm |  | [***]                          |  | [***]                         
|441220                                   |  | MDIV Threaded Dowel 20 x 23mm |  | [***]                          |  | [***]                         
|441222                                   |  | MDIV Threaded Dowel 22 x 23mm |  | [***]                          |  | [***]                         
|441224                                   |  | MDIV Threaded Dowel 24 x 23mm |  | [***]                          |  | [***]                         
|441318                                   |  | MDIV Threaded Dowel 18 x 26mm |  | [***]                          |  | [***]                         
|441320                                   |  | MDIV Threaded Dowel 20 x 26mm |  | [***]                          |  | [***]                         
|441322                                   |  | MDIV Threaded Dowel 22 x 26mm |  | [***]                          |  | [***]                         
|                                         |  |                              
|Osteofil RT ICM Moldable                 |  |                               |  |                               
|004505                                   |  | Osteofil RT ICM Moldable 5cc  |  | [***]                          |  | [***]                         
|004510                                   |  | Osteofil RT ICM Moldable 10cc |  | [***]                          |  | [***]                         
|004520                                   |  | Osteofil RT ICM Moldable 20cc |  | [***]                          |  | [***]                         
|                                         |  |                              
|Osteofil RT Paste                        |  |                               |  |                               
|004401   *                               |  | Osteofil Paste - RT 1cc       |  | [***]                          |  | [***]                         
|004601                                   |  | Osteofil Paste - RT 1cc       |  | [***]                          |  | [***]                         
|004405   *                               |  | Osteofil Paste - RT 5cc       |  | [***]                          |  | [***]                         
|004605                                   |  | Osteofil Paste - RT 5cc       |  | [***]                          |  | [***]                         
|004410   *                               |  | Osteofil Paste - RT 10cc      |  | [***]                          |  | [***]                         
|004610                                   |  | Osteofil Paste - RT 10cc      |  | [***]                          |  | [***]                         
|044005   *                               |  | Osteofil Paste - RT 0.5cc     |  | [***]                          |  | [***]                         
|046005                                   |  | Osteofil Paste - RT 0.5cc     |  | [***]                          |  | [***]                         
|*                                        |  | Product code being phased out |  |                                |  |                               
|                                         |  |                              
|Osteofil Frozen Paste                    |  |                               |  |                               
|002401                                   |  | Osteofil Paste Frozen 1cc     |  | [***]                          |  | [***]                         
|002405                                   |  | Osteofil Paste Frozen 5cc     |  | [***]                          |  | [***]                         
|002410                                   |  | Osteofil Paste Frozen 10cc    |  | [***]                          |  | [***]                         
|024005                                   |  | Osteofil Paste Frozen 0.5cc   |  | [***]                          |  | [***]                         
|                                         |  |                               | 
|Osteofil -IC                             |  |                               |  |                                |  |                               
|002705                                   |  | Osteofil - IC 5cc             |  | [***]                          |  | [***]                         
|002710                                   |  | Osteofil - IC 10cc            |  | [***]                          |  | [***]                         
|002720                                   |  | Osteofil - IC 20cc            |  | [***]                          |  | [***]                         
|                                         |  |                              
|Osteofil ICM Frozen Strips               |  |                               |  |                               
|002350                                   |  | Osteofil - ICM 50mm           |  | [***]                          |  | [***]                         
|002390                                   |  | Osteofil - ICM 90mm           |  | [***]                          |  | [***]                         

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

NEW PRODUCT ADDITIONS May 1, 2005

EXCLUSIVE



|                                           |  |                                      |  |                               
|------------------------------------------ |  | ------------------------------------ |  | ------------------------------
|Product Code                               |  | Description                          |  | Column B LSF Effective5/1/2005
|Cornerstone SR Assembled Cortical          |  |                                     
|330511                                     |  | ACSR Cortical Block 5 x 11 x 11mm    |  | [***]                         
|330541                                     |  | ACSR Cortical Block 5 x 14 x 11mm    |  | [***]                         
|330544                                     |  | ACSR Cortical Block 5 x 11 x 14mm    |  | [***]                         
|330611                                     |  | ACSR Cortical Block 6 x 11 x 11mm    |  | [***]                         
|330641                                     |  | ACSR Cortical Block 6 x 14 x 11mm    |  | [***]                         
|330644                                     |  | ACSR Cortical Block 6 x 14 x 14mm    |  | [***]                         
|330711                                     |  | ACSR Cortical Block 7 x 11 x 11mm    |  | [***]                         
|330741                                     |  | ACSR Cortical Block 7 x 14 x 11mm    |  | [***]                         
|330744                                     |  | ACSR Cortical Block 7 x 14 x 14mm    |  | [***]                         
|330811                                     |  | ACSR Cortical Block 8 x 11 x 11mm    |  | [***]                         
|330841                                     |  | ACSR Cortical Block 8 x 14 x 11mm    |  | [***]                         
|330844                                     |  | ACSR Cortical Block 8 x 14 x 14mm    |  | [***]                         
|330911                                     |  | ACSR Cortical Block 9 x 11 x 11mm    |  | [***]                         
|330941                                     |  | ACSR Cortical Block 9 x 14 x 11mm    |  | [***]                         
|330944                                     |  | ACSR Cortical Block 9 x 14 x 14mm    |  | [***]                         
|331011                                     |  | ACSR Cortical Block 10 x 11 x 11mm   |  | [***]                         
|331041                                     |  | ACSR Cortical Block 10 x 14 x 11mm   |  | [***]                         
|331044                                     |  | ACSR Cortical Block 10 x 14 x 14mm   |  | [***]                         
|331111                                     |  | ACSR Cortical Block 11 x 11 x 11mm   |  | [***]                         
|331141                                     |  | ACSR Cortical Block 11 x 14 x 11mm   |  | [***]                         
|331144                                     |  | ACSR Cortical Block 11 x 14 x 14mm   |  | [***]                         
|331211                                     |  | ACSR Cortical Block 12 x 11 x 11mm   |  | [***]                         
|331241                                     |  | ACSR Cortical Block 12 x 14 x 11mm   |  | [***]                         
|331244                                     |  | ACSR Cortical Block 12 x 14 x 14mm   |  | [***]                         
|331311                                     |  | ACSR Cortical Block 13 x 11 x 11mm   |  | [***]                         
|331341                                     |  | ACSR Cortical Block 13 x 14 x 11mm   |  | [***]                         
|331344                                     |  | ACSR Cortical Block 13 x 14 x 14mm   |  | [***]                         
|                                           | 
|Cornerstone Lordotic SR Assembled Cortical |  |                                     
|340511                                     |  | L-ACSR Cortical Block 5 x 11 x 11mm  |  | [***]                         
|340541                                     |  | L-ACSR Cortical Block 5 x 14 x 11mm  |  | [***]                         
|340544                                     |  | L-ACSR Cortical Block 5 x 14 x 14mm  |  | [***]                         
|340611                                     |  | L-ACSR Cortical Block 6 x 11 x 11mm  |  | [***]                         
|340641                                     |  | L-ACSR Cortical Block 6 x 14 x 11mm  |  | [***]                         
|340644                                     |  | L-ACSR Cortical Block 6 x 14 x 14mm  |  | [***]                         
|340711                                     |  | L-ACSR Cortical Block 7 x 11 x 11mm  |  | [***]                         
|340741                                     |  | L-ACSR Cortical Block 7 x 14 x 11mm  |  | [***]                         
|340744                                     |  | L-ACSR Cortical Block 7 x 14 x 14mm  |  | [***]                         
|340811                                     |  | L-ACSR Cortical Block 8 x 11 x 11mm  |  | [***]                         
|340841                                     |  | L-ACSR Cortical Block 8 x 14 x 11mm  |  | [***]                         
|340844                                     |  | L-ACSR Cortical Block 8 x 14 x 14mm  |  | [***]                         
|340911                                     |  | L-ACSR Cortical Block 9 x 11 x 11mm  |  | [***]                         
|340941                                     |  | L-ACSR Cortical Block 9 x 14 x 11mm  |  | [***]                         
|340944                                     |  | L-ACSR Cortical Block 9 x 14 x 14mm  |  | [***]                         
|341011                                     |  | L-ACSR Cortical Block 10 x 11 x 11mm |  | [***]                         
|341041                                     |  | L-ACSR Cortical Block 10 x 14 x 11mm |  | [***]                         
|341044                                     |  | L-ACSR Cortical Block 10 x 14 x 14mm |  | [***]                         
|341111                                     |  | L-ACSR Cortical Block 11 x 11 x 11mm |  | [***]                         
|341141                                     |  | L-ACSR Cortical Block 11 x 14 x 11mm |  | [***]                         
|341144                                     |  | L-ACSR Cortical Block 11 x 14 x 14mm |  | [***]                         

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).

---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

NEW PRODUCT ADDITIONS May 1, 2005

EXCLUSIVE



|                                                             |  |                                                      |  |                                
|------------------------------------------------------------ |  | ---------------------------------------------------- |  | -------------------------------
|Product Code                                                 |  | Description                                          |  | Column B LSF Effective 5/1/2005
|Cornerstone Lordotic SR Assembled Cortical                   |  |                                                     
|341211                                                       |  | L-ACSR Cortical Block 12 x 11 x 11mm                 |  | [***]                          
|341241                                                       |  | L-ACSR Cortical Block 12 x 14 x 11mm                 |  | [***]                          
|341244                                                       |  | L-ACSR Cortical Block 12 x 14 x 14mm                 |  | [***]                          
|                                                             | 
|Cornerstone ASR/Lordotic ASR (Assembled Cortical-Cancellous) |  |                                                     
|245541                                                       |  | ASR Cortical-Cancellous Block 5 x 14 x 11mm          |  | [***]                          
|245641                                                       |  | ASR Cortical-Cancellous Block 6 x 14 x 11mm          |  | [***]                          
|345511                                                       |  | Lordotic ASR Cortical-Cancellous Block 5 x 11 x 11mm |  | [***]                          
|345541                                                       |  | Lordotic ASR Cortical-Cancellous Block 5 x 14 x 11mm |  | [***]                          
|345544                                                       |  | Lordotic ASR Cortical-Cancellous Block 5 x 14 x 14mm |  | [***]                          
|345611                                                       |  | Lordotic ASR Cortical-Cancellous Block 6 x 11 x 11mm |  | [***]                          
|345641                                                       |  | Lordotic ASR Cortical-Cancellous Block 6 x 14 x 11mm |  | [***]                          
|345644                                                       |  | Lordotic ASR Cortical-Cancellous Block 6 x 14 x 14mm |  | [***]                          
|                                                             | 
|Boomerang TLIF Assembled                                     |  |                                                     
|293007                                                       |  | Boomerang / Crescent Bone 7mm                        |  | [***]                          
|293008                                                       |  | Boomerang / Crescent Bone 8mm                        |  | [***]                          
|293009                                                       |  | Boomerang / Crescent Bone 9mm                        |  | [***]                          
|293010                                                       |  | Boomerang / Crescent Bone 10mm                       |  | [***]                          
|293011                                                       |  | Boomerang / Crescent Bone 11mm                       |  | [***]                          
|293012                                                       |  | Boomerang / Crescent Bone 12mm                       |  | [***]                          
|293013                                                       |  | Boomerang / Crescent Bone 13mm                       |  | [***]                          
|293014                                                       |  | Boomerang / Crescent Bone 14mm                       |  | [***]                          

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to
Section 3.1(e).



---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

NON-EXCLUSIVE



|                              |  |                                                |  |                   |  |                               
|----------------------------- |  | ---------------------------------------------- |  | ----------------- |  | ------------------------------
|Product Code                  |  | Description                                    |  | Column A LSF 2004 |  | Column BLSF Effective 7/1/2005
|Cancellous Chips              |  |                                                |  |                  
|100015                        |  | Cancellous Chips (1-4mm) 15cc                  |  | [***]             |  | [***]                         
|100030                        |  | Cancellous Chips (1-4mm) 30cc                  |  | [***]             |  | [***]                         
|100415                        |  | Cancellous Chips (4-10mm) 15cc                 |  | [***]             |  | [***]                         
|100430                        |  | Cancellous Chips (4-10mm) 30cc                 |  | [***]             |  | [***]                         
|                              |  |                                               
|Cancellous Cubes              |  |                                                |  |                  
|100315                        |  | Cancellous Cubes (6-10mm) 15cc                 |  | [***]             |  | [***]                         
|100330                        |  | Cancellous Cubes (6-10mm) 30cc                 |  | [***]             |  | [***]                         
|100215                        |  | Cancellous Cubes (4-6mm) 15cc                  |  | [***]             |  | [***]                         
|100230                        |  | Cancellous Cubes (4-6mm) 30cc                  |  | [***]             |  | [***]                         
|                              |  |                                               
|Cortical and Cancellous Chips |  |                                                |  |                  
|110115                        |  | Cortical Cancellous Chips (1-3mm) 15cc         |  | [***]             |  | [***]                         
|110130                        |  | Cortical Cancellous Chips (1-3mm) 30cc         |  | [***]             |  | [***]                         
|                              |  |                                               
|Cortical Strips               |  |                                                |  |                  
|271160                        |  | Cortical Strip 45-65mm (L) x 2-3               |  | [***]             |  | [***]                         
|271260                        |  | Cortical Strip 45-65mm (L) x 4-5               |  | [***]             |  | [***]                         
|271460                        |  | Cortical Strip 45-65mm (L) x 6-7               |  | [***]             |  | [***]                         
|273210                        |  | Cortical Strip 90-110mm (L) x 9-11             |  | [***]             |  | [***]                         
|273215                        |  | Cortical Strip 111-179mm (L) x 9-11            |  | [***]             |  | [***]                         
|273415                        |  | Cortical Strip 111-179mm (L) x 14-16           |  | [***]             |  | [***]                         
|273615                        |  | Cortical Strip 111-179mm (L) x 18-20           |  | [***]             |  | [***]                         
|                              |  |                                               
|Ilium Strips                  |  |                                                |  |                  
|330030                        |  | Ilium Strip, Tricortical 28-45mm (L)           |  | [***]             |  | [***]                         
|330050                        |  | Ilium Strip, Tricortical 46-57mm (L)           |  | [***]             |  | [***]                         
|330060                        |  | Ilium Strip, Tricortical >58mm (L)             |  | [***]             |  | [***]                         
|                              |  |                                               
|Cortical Cancellous Strips    |  |                                                |  |                  
|351260                        |  | Cortical Cancellous Strips 58-62mm (L) x 4-6mm |  | [***]             |  | [***]                         
|                              |  |                                               
|Cortical Wedge                |  |                                                |  |                  
|752020                        |  | Cortical Wedge 10mm, FZD                       |  | [***]             |  | [***]                         
|752820                        |  | Cortical Wedge 8mm, FZD                        |  | [***]             |  | [***]                         
|                              |  |                                               
|Bicortical Block2             |  |                                                |  |                  
|882006                        |  | Bicortical Block (Parallel) 6mm                |  | [***]             |  | [***]                         
|882007                        |  | Bicortical Block (Parallel) 7mm                |  | [***]             |  | [***]                         
|882008                        |  | Bicortical Block (Parallel) 8mm                |  | [***]             |  | [***]                         
|882009                        |  | Bicortical Block (Parallel) 9mm                |  | [***]             |  | [***]                         
|882010                        |  | Bicortical Block (Parallel) 10mm               |  | [***]             |  | [***]                         

---

|2 | RTI agrees that it will not distribute these bicortical parallel blocks in the Exclusive Territory
|- | --------------------------------------------------------------------------------------------------

Exclusive in the Exclusive Territory and non-exclusive elsewhere in the Territory subject to Section 3.1(e).



---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

Attachment B to Second Amendment to First Amended Exclusive License and Distribution

Orders for Exclusivity Provision Calculation



|               |  |                                       |  |       |  |       |  |      
|-------------- |  | ------------------------------------- |  | ----- |  | ----- |  | -----
|Product Number |  | Description                           |  | Total |  | 75%   |  | 25%  
|002350         |  | Osteofil ICM Moldable 50mm            |  | [***] |  | [***] |  | [***]
|002390         |  | Osteofil ICM Moldable 90mm            |  | [***] |  | [***] |  | [***]
|002401         |  | Osteofil Paste 1cc                    |  | [***] |  | [***] |  | [***]
|002405         |  | Osteofil Paste 5cc                    |  | [***] |  | [***] |  | [***]
|002410         |  | Osteofil Paste 10cc                   |  | [***] |  | [***] |  | [***]
|004401         |  | Osteofil RT Paste 1cc                 |  | [***] |  | [***] |  | [***]
|004410         |  | Osteofil RT Paste 10cc                |  | [***] |  | [***] |  | [***]
|004505         |  | Osteofil RT ICM Moldable 5cc          |  | [***] |  | [***] |  | [***]
|004510         |  | Osteofil RT ICM Moldable 10cc         |  | [***] |  | [***] |  | [***]
|024005         |  | Osteofil Paste 0.5cc                  |  | [***] |  | [***] |  | [***]
|100015         |  | Cancellous Chips (1-4mm) 15cc         |  | [***] |  | [***] |  | [***]
|100030         |  | Cancellous Chips (1-4mm) 30cc         |  | [***] |  | [***] |  | [***]
|100090         |  | Cancellous Chips (1-4mm) 90cc         |  | [***] |  | [***] |  | [***]
|100460         |  | Cancellous Chips (4-10mm) 60cc        |  | [***] |  | [***] |  | [***]
|110130         |  | Cort/Canc Blend(1-3mm) 30cc           |  | [***] |  | [***] |  | [***]
|170820         |  | Impacted Wedge FZD 8x20               |  | [***] |  | [***] |  | [***]
|170826         |  | Impacted Wedge FZD 8x26               |  | [***] |  | [***] |  | [***]
|171020         |  | Impacted Wedge FZD 10x20              |  | [***] |  | [***] |  | [***]
|171026         |  | Impacted Wedge FZD 10x26              |  | [***] |  | [***] |  | [***]
|171220         |  | Impacted Wedge FZD 12x20              |  | [***] |  | [***] |  | [***]
|171226         |  | Impacted Wedge FZD 12x26              |  | [***] |  | [***] |  | [***]
|171426         |  | Impacted Wedge FZD 14x27              |  | [***] |  | [***] |  | [***]
|200511         |  | SR Bone 5 x 11 x 11 FZD               |  | [***] |  | [***] |  | [***]
|200541         |  | SR Bone 5 x 14 x 11 FZD               |  | [***] |  | [***] |  | [***]
|200611         |  | SR Bone 6 x 11 x 11 FZD               |  | [***] |  | [***] |  | [***]
|200641         |  | SR Bone 6 x 14 x 11 FZD               |  | [***] |  | [***] |  | [***]
|200644         |  | SR Bone 6 x 14 x 14 FZD               |  | [***] |  | [***] |  | [***]
|200744         |  | SR Bone 7 x 14 x 14 FZD               |  | [***] |  | [***] |  | [***]
|201041         |  | SR Bone 10 x 14 x 11 FZD              |  | [***] |  | [***] |  | [***]
|201141         |  | SR Bone 11 x 14 x 11 FZD              |  | [***] |  | [***] |  | [***]
|201241         |  | SR Bone 12 x 14 x 11 FZD              |  | [***] |  | [***] |  | [***]
|210600         |  | Select Bone 6mm FZD                   |  | [***] |  | [***] |  | [***]
|210700         |  | Select Bone 7mm FZD                   |  | [***] |  | [***] |  | [***]
|210900         |  | Select Bone 9mm FZD                   |  | [***] |  | [***] |  | [***]
|211000         |  | Select Bone 10mm FZD                  |  | [***] |  | [***] |  | [***]
|211100         |  | Select Bone 11mm FZD                  |  | [***] |  | [***] |  | [***]
|213500         |  | Select Bone 35mm FZD                  |  | [***] |  | [***] |  | [***]
|245241         |  | ACC-SR 10 x 14 x 11mm                 |  | [***] |  | [***] |  | [***]
|245741         |  | ACC-SR 7 x 14 x 11mm                  |  | [***] |  | [***] |  | [***]
|245841         |  | ACC-SR 8 x 14 x 11mm                  |  | [***] |  | [***] |  | [***]
|245941         |  | ACC-SR 9 x 14 x 11mm                  |  | [***] |  | [***] |  | [***]
|270060         |  | Cortical Ring w/ Cancellous Plug 6mm  |  | [***] |  | [***] |  | [***]
|270070         |  | Cortical Ring w/ Cancellous Plug 7mm  |  | [***] |  | [***] |  | [***]
|270080         |  | Cortical Ring w/ Cancellous Plug 8mm  |  | [***] |  | [***] |  | [***]
|270090         |  | Cortical Ring w/ Cancellous Plug 9mm  |  | [***] |  | [***] |  | [***]
|270110         |  | Cortical Ring w/ Cancellous Plug 11mm |  | [***] |  | [***] |  | [***]
|271260         |  | Cortical Strips 45-65mmL x 4-5mm      |  | [***] |  | [***] |  | [***]
|273210         |  | Cortical Strips 90-110mm x 9-11mm     |  | [***] |  | [***] |  | [***]
|373415         |  | Cortical Strips 111-179mm x 14-16mm   |  | [***] |  | [***] |  | [***]

---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



---

|               |  |                                       |  |       |  |       |  |      
|-------------- |  | ------------------------------------- |  | ----- |  | ----- |  | -----
|Product Number |  | Description                           |  | Total |  | 75%   |  | 25%  
|280016         |  | 15mm Unicortical Dowel                |  | [***] |  | [***] |  | [***]
|300511         |  | Cornerstone L-SR 5 x 11 x 11          |  | [***] |  | [***] |  | [***]
|300541         |  | Cornerstone L-SR 5 x 14 x 11          |  | [***] |  | [***] |  | [***]
|300544         |  | Cornerstone L-SR 5 x 14 x 14          |  | [***] |  | [***] |  | [***]
|300611         |  | Cornerstone L-SR 6 x 11 x 11          |  | [***] |  | [***] |  | [***]
|300644         |  | Cornerstone L-SR 6 x 14 x 14          |  | [***] |  | [***] |  | [***]
|310109         |  | Ilium Block Tricortical 9mm x 15mm    |  | [***] |  | [***] |  | [***]
|345041         |  | Cornerstone L-ASR 10 x 14 x 11        |  | [***] |  | [***] |  | [***]
|345044         |  | Cornerstone L-ASR 10 x 14 x 14        |  | [***] |  | [***] |  | [***]
|345111         |  | Cornerstone L-ASR 11 x 11 x 11        |  | [***] |  | [***] |  | [***]
|345141         |  | Cornerstone L-ASR 11 x 14 x 11        |  | [***] |  | [***] |  | [***]
|345211         |  | Cornerstone L-ASR 12 x 11 x 11        |  | [***] |  | [***] |  | [***]
|345241         |  | Cornerstone L-ASR 12 x 14 x 11        |  | [***] |  | [***] |  | [***]
|345244         |  | Cornerstone L-ASR 12 x 14 x 14        |  | [***] |  | [***] |  | [***]
|345711         |  | Cornerstone L-ASR 7 x 11 x 11         |  | [***] |  | [***] |  | [***]
|345744         |  | Cornerstone L-ASR 7 x 14 x 14         |  | [***] |  | [***] |  | [***]
|345811         |  | Cornerstone L-ASR 8 x 11 x 11         |  | [***] |  | [***] |  | [***]
|345841         |  | Cornerstone L-ASR 8 x 14 x 11         |  | [***] |  | [***] |  | [***]
|345844         |  | Cornerstone L-ASR 8 x 14 x 14         |  | [***] |  | [***] |  | [***]
|345941         |  | Cornerstone L-ASR 9 x 14 x 11         |  | [***] |  | [***] |  | [***]
|345944         |  | Cornerstone L-ASR 9 x 14 x 14         |  | [***] |  | [***] |  | [***]
|351260         |  | Cancellous/Cortical Strip 58-60mmx4-6 |  | [***] |  | [***] |  | [***]
|401114         |  | MDII Threaded Dowel FZ 14x20          |  | [***] |  | [***] |  | [***]
|401116         |  | MDII Threaded Dowel FZ 16x20          |  | [***] |  | [***] |  | [***]
|401118         |  | MDII Threaded Dowel FZ 18x20          |  | [***] |  | [***] |  | [***]
|401120         |  | MDII Threaded Dowel FZ 20x20          |  | [***] |  | [***] |  | [***]
|401214         |  | MDII Threaded Dowel FZ 14x23          |  | [***] |  | [***] |  | [***]
|401220         |  | MDII Threaded Dowel FZ 20x23          |  | [***] |  | [***] |  | [***]
|401316         |  | MDII Threaded Dowel FZ 16x26          |  | [***] |  | [***] |  | [***]
|401318         |  | MDII Threaded Dowel FZ 18x26          |  | [***] |  | [***] |  | [***]
|401320         |  | MDII Threaded Dowel FZ 20x26          |  | [***] |  | [***] |  | [***]
|439012         |  | 12mm x 26mm Cortical Ring FZD         |  | [***] |  | [***] |  | [***]
|439014         |  | 14mm x 26mm Cortical Ring FZD         |  | [***] |  | [***] |  | [***]
|439016         |  | 16mm x 26mm Cortical Ring FZD         |  | [***] |  | [***] |  | [***]
|441220         |  | MDIV 20 x 23                          |  | [***] |  | [***] |  | [***]
|451266         |  | 12x26x26 Precision Graft              |  | [***] |  | [***] |  | [***]
|545541         |  | Cornerstone Pinnacle 5x14x11          |  | [***] |  | [***] |  | [***]
|645511         |  | Cornerstone Pinnacle-L 5x11x11        |  | [***] |  | [***] |  | [***]
|645541         |  | Cornerstone Pinnacle-L 5x14x11        |  | [***] |  | [***] |  | [***]
|645611         |  | Cornerstone Pinnacle-L 6x11x11        |  | [***] |  | [***] |  | [***]
|850912         |  | Unicortical Block 9x12mm              |  | [***] |  | [***] |  | [***]
|862012         |  | Bicortical Block 12mm x 20mm          |  | [***] |  | [***] |  | [***]
|872008         |  | Bicortical Block 8mm                  |  | [***] |  | [***] |  | [***]

---

|[***] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.
|----- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------