EX-10.1





 Exhibit 10.1 

CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE IT IS NOT MATERIAL AND WOULD LIKELY
CAUSE COMPETITIVE HARM TO THE COMPANY IF PUBLICLY DISCLOSED. 
 Execution Version 

 
  

 
  
 



 
 CREDIT AGREEMENT 

dated as of 
 October 25,
2019, 
 by and among 
 KALEIDO
BIOSCIENCES, INC., 
 CADENA BIO, INC., 

and 
 JPMORGAN CHASE BANK, N.A.

  
  

 












 CREDIT AGREEMENT dated as of October 25, 2019 (as it may be amended or modified from
time to time, this “Agreement”), by and among KALEIDO BIOSCIENCES, INC., a Delaware corporation, and CADENA BIO, INC., a Delaware corporation (each a “Borrower” and collectively, “Borrowers”), the other Loan
Parties party hereto, and JPMORGAN CHASE BANK, N.A., as Lender. 
 The parties hereto agree as follows: 

ARTICLE I 
 Definitions

 SECTION 1.01.    Defined Terms. As used in this Agreement, the following terms have the meanings specified
below: 
 “Account” has the meaning assigned to such term in the Security Agreement. 

“Account Debtor” means any Person obligated on an Account. 

“Adjusted LIBO Rate” means, with respect to the Term Loan, an interest rate per annum (rounded upwards, if necessary, to the
next 1/16 of 1%) equal to (a) the LIBO Rate for a one-month interest period multiplied by (b) the Statutory Reserve Rate. 

“Adjusted One Month LIBOR Rate” means, for any day, an interest rate per annum equal to the sum of (i) 2.50% per annum plus
(ii) the Adjusted LIBO Rate for a one-month interest period on such day (or if such day is not a Business Day, the immediately preceding Business Day); provided that, for the avoidance of doubt, the
Adjusted LIBO Rate for any day shall be based on the LIBO Screen Rate at approximately 11:00 a.m. London time on such day. 

“Affiliate” means, with respect to a specified Person, another Person that directly, or indirectly through one or more
intermediaries, Controls or is Controlled by or is under common Control with the specified Person. 
 “Anti-Corruption
Laws” means all laws, rules, and regulations of any jurisdiction applicable to any Borrower or any of its Subsidiaries from time to time concerning or relating to bribery or corruption. 

“Banking Services” means each and any of the following bank services provided to any Loan Party by Lender or any of its
Affiliates: (a) credit cards for commercial customers (including, without limitation, “commercial credit cards” and purchasing cards), (b) stored value cards, (c) merchant processing services, and (d) treasury management
services (including, without limitation, controlled disbursement, automated clearinghouse transactions, return items, any direct debit scheme or arrangement, overdrafts and interstate depository network services). 

“Banking Services Obligations” means any and all obligations of the Loan Parties, whether absolute or contingent and
howsoever and whensoever created, arising, evidenced or acquired (including all renewals, extensions and modifications thereof and substitutions therefor) in connection with Banking Services. 

“Bankruptcy Event” means, with respect to any Person, when such Person becomes the subject of a voluntary or involuntary
bankruptcy or insolvency proceeding, or has had a receiver, conservator, trustee, administrator, custodian, assignee for the benefit of creditors or similar Person charged with the reorganization or liquidation of its business appointed for it, or,
in the good faith determination of Lender, has taken any action in furtherance of, or indicating its consent to, approval of, or acquiescence in, any such proceeding or appointment or has had any order for relief in such proceeding entered in
respect thereof, provided that a Bankruptcy Event shall not result solely by virtue of any ownership interest, or the acquisition of any ownership interest, in such Person by a Governmental Authority or instrumentality thereof, unless such ownership
interest results in or provides such Person with immunity from the jurisdiction of courts within the U.S. or from the enforcement of judgments or writs of attachment on its assets or permits such Person (or such Governmental Authority or
instrumentality) to reject, repudiate, disavow or disaffirm any contracts or agreements made by such Person. 
 “Beneficial
Ownership Certification” means a certification regarding beneficial ownership as required by the Beneficial Ownership Regulation. 

“Beneficial Ownership Regulation” means 31 C.F.R. § 1010.230. 

“Borrower(s)” means each of Kaleido Biosciences, Inc., a Delaware corporation, and Cadena Bio, Inc., a Delaware corporation.

 “Borrower Representative” has the meaning assigned to such term in Section 9.01. 

“Borrowing Request” means a request by Borrower Representative for the Term Loan in accordance with Section 2.02, which
shall be in a form satisfactory to, or provided by, Lender. 

  
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 “Business Day” means any day that is not a Saturday, Sunday or other day on
which commercial banks in New York City are authorized or required by law to remain closed. 
 “Capital Lease Obligations”
of any Person means the obligations of such Person to pay rent or other amounts under any lease of (or other arrangement conveying the right to use) real or personal property, or a combination thereof, which obligations are required to be classified
and accounted for as capital leases or financing leases on a balance sheet of such Person under GAAP, and the amount of such obligations shall be the capitalized amount thereof determined in accordance with GAAP. 

“Cash Burn” means (i) cash flow from operations (determined in accordance with GAAP) minus (ii) capitalized
expenditures. 
 “CB Floating Rate” means the Prime Rate; provided that the CB Floating Rate shall never be less than the
Adjusted One Month LIBOR Rate on such day (or if such day is not a Business Day, the immediately preceding Business Day). Any change in the CB Floating Rate due to a change in the Prime Rate or the Adjusted One Month LIBOR Rate shall be effective
from and including the effective date of such change in the Prime Rate or the Adjusted One Month LIBOR Rate, respectively. 

“Change in Control” means (a) occupation at any time of a majority of the seats (other than vacant seats) on the board
of directors of any Borrower by Persons who were not (i) directors of such Borrower on the date of this Agreement, nominated, appointed, or approved by the board of directors of such Borrower or (ii) appointed by directors so nominated,
appointed, or approved, (b) the acquisition of direct or indirect Control of any Borrower by any Person or group; (c) Borrowers shall cease to own, free and clear of all Liens or other encumbrances, 100% of the outstanding voting Equity
Interests of each of their Subsidiaries on a fully diluted basis; or (d) a Borrower shall cease to own and control, of record and beneficially, directly or indirectly, 100% of each class of outstanding capital stock of each Subsidiary of such
Borrower free and clear of all Liens (except Liens created by this Agreement). 
 “Change in Law” means the occurrence
after the date of this Agreement of any of the following: (a) the adoption of or taking effect of any law, rule, regulation or treaty, (b) any change in any law, rule, regulation or treaty or in the administration, interpretation,
implementation or application thereof by any Governmental Authority, or (c) compliance by Lender (or, for purposes of Section 2.10, by any lending office of Lender or by Lender’s holding company, if any) with any request, guideline,
requirement or directive (whether or not having the force of law) of any Governmental Authority made or issued after the date of this Agreement; provided that, notwithstanding anything herein to the contrary, (x) the Dodd-Frank Wall Street
Reform and Consumer Protection Act and all requests, rules, guidelines, requirements or directives thereunder or issued in connection therewith or in the implementation thereof, and (y) all requests, rules, guidelines, requirements or
directives promulgated by the Bank for International Settlements, the Basel Committee on Banking Supervision (or any successor or similar authority) or the U.S. or foreign regulatory authorities, in each case pursuant to Basel III, shall in each
case be deemed to be a “Change in Law”, regardless of the date enacted, adopted, issued or implemented. 

“Charges” has the meaning assigned to such term in Section 8.16. 

“Code” means the Internal Revenue Code of 1986, as amended from time to time. 

“Collateral” means any and all property owned, leased or operated by a Person covered by the Collateral Documents and any and
all other property of any Loan Party, now existing or hereafter acquired, that may at any time be, become or be intended to be, subject to a security interest or Lien in favor of Lender, on behalf of the Secured Parties, to secure the Secured
Obligations. 
 “Collateral Access Agreement” has the meaning assigned to such term in the Security Agreement. 

“Collateral Documents” means, collectively, the Security Agreement and any other agreements, instruments and documents
executed in connection with this Agreement that are intended to create, perfect or evidence Liens to secure the Secured Obligations, including, without limitation, all other security agreements, pledge agreements, mortgages, deeds of trust, loan
agreements, notes, guarantees, subordination agreements, pledges, powers of attorney, consents, assignments, contracts, fee letters, notices, leases, financing statements and all other written matter whether theretofore, now or hereafter executed by
any Loan Party and delivered to Lender. 
 “Compliance Certificate” has the meaning assigned to such term in
Section 5.01(c). 
 “Control” means the possession, directly or indirectly, of the power to direct or cause the
direction of the management or policies of a Person, whether through the ability to exercise voting power, by contract or otherwise. “Controlling” and “Controlled” have meanings correlative thereto. 

“Default” means any event or condition which constitutes an Event of Default or which upon notice, lapse of time or both
would, unless cured or waived, become an Event of Default. 

  
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 “Disposition” or “Dispose” means the sale, transfer,
license, lease or other disposition (in one transaction or in a series of transactions and whether effected pursuant to a Division or otherwise) of any property by any Person (including any sale and leaseback transaction and any issuance of Equity
Interests by a Subsidiary of such Person), including any sale, assignment, transfer or other disposal, with or without recourse, of any notes or accounts receivable or any rights and claims associated therewith. 

“Dividing Person” has the meaning assigned to it in the definition of “Division.” 

“Division” means the division of the assets, liabilities and/or obligations of a Person (the “Dividing
Person”) among two or more Persons (whether pursuant to a “plan of division” or similar arrangement), which may or may not include the Dividing Person and pursuant to which the Dividing Person may or may not survive. 

“Division Successor” means any Person that, upon the consummation of a Division of a Dividing Person, holds all or any
portion of the assets, liabilities and/or obligations previously held by such Dividing Person immediately prior to the consummation of such Division. A Dividing Person which retains any of its assets, liabilities and/or obligations after a Division
shall be deemed a Division Successor upon the occurrence of such Division. 
 “Disclosed Matters” means the actions, suits,
proceedings and environmental matters disclosed in Schedule 3.06. 
 “Document” has the meaning
assigned to such term in the Security Agreement. 
 “Dollars”, “dollars” or “$” refers to
lawful money of the U.S. 
 “Effective Date” means the date on which the conditions specified in Section 4.01 are
satisfied (or waived in accordance with Section 8.02). 
 “Electronic Signature” means an electronic sound, symbol, or
process attached to, or associated with, a contract or other record and adopted by a Person with the intent to sign, authenticate or accept such contract or record. 

“Electronic System” means any electronic system, including e-mail, e-fax, web portal access for Borrowers, and any other Internet or extranet-based site, whether such electronic system is owned, operated or hosted by Lender and any of its respective Related Parties or any other
Person, providing for access to data protected by passcodes or other security system. 
 “Environmental Laws” means all
laws, rules, regulations, codes, ordinances, orders, decrees, judgments, injunctions, notices or binding agreements issued, promulgated or entered into by any Governmental Authority, relating in any way to the (i) environment, (ii) preservation
or reclamation of natural resources, (iii) the management, Release or threatened Release of any Hazardous Material or (iv) health and safety matters. 

“Environmental Liability” means any liability, contingent or otherwise (including any liability for damages, costs of
environmental remediation, fines, penalties or indemnities), of a Borrower or any Subsidiary directly or indirectly resulting from or based upon (a) any violation of any Environmental Law, (b) the generation, use, handling, transportation,
storage, treatment or disposal of any Hazardous Materials in violation of any Environmental Law, (c) any exposure to any Hazardous Materials in violation of any Environmental Law, (d) the Release or threatened Release of any Hazardous
Materials into the environment in violation of any Environmental Law, or (e) any contract, agreement or other consensual arrangement pursuant to which liability is assumed or imposed with respect to any of the foregoing. 

“Equipment” has the meaning assigned to such term in the Security Agreement. 

“Equity Interests” means shares of capital stock, partnership interests, membership interests in a limited liability company,
beneficial interests in a trust or other equity ownership interests in a Person, and any warrants, options or other rights entitling the holder thereof to purchase or acquire any of the foregoing, but excluding any debt securities convertible into
any of the foregoing. 
 “ERISA” means the Employee Retirement Income Security Act of 1974, as amended from time to time,
and the rules and regulations promulgated thereunder. 
 “Event of Default” has the meaning assigned to such term in
Section 7.01. 
 “Federal Reserve Board” means the Board of Governors of the Federal Reserve System of the United
States of America. 
 “Financial Officer” means the chief financial officer, principal accounting officer, treasurer or
controller of a Borrower. 
 “Funding Account” has the meaning assigned to such term in Section 4.01(h). 

“GAAP” means generally accepted accounting principles in the U.S. 

  
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 “Governmental Authority” means the government of the U.S., any other nation
or any political subdivision thereof, whether state or local, and any agency, authority, instrumentality, regulatory body, court, central bank or other entity exercising executive, legislative, judicial, taxing, regulatory or administrative powers
or functions of or pertaining to government. 
 “Guarantee” of or by any Person (the “guarantor”) means
any obligation, contingent or otherwise, of the guarantor guaranteeing or having the economic effect of guaranteeing any Indebtedness or other obligation of any other Person (the “primary obligor”) in any manner, whether directly or
indirectly, and including any obligation of the guarantor, direct or indirect, (a) to purchase or pay (or advance or supply funds for the purchase or payment of) such Indebtedness or other obligation or to purchase (or to advance or supply
funds for the purchase of) any security for the payment thereof, (b) to purchase or lease property, securities or services for the purpose of assuring the owner of such Indebtedness or other obligation of the payment thereof, (c) to
maintain working capital, equity capital or any other financial statement condition or liquidity of the primary obligor so as to enable the primary obligor to pay such Indebtedness or other obligation or (d) as an account party in respect of
any letter of credit or letter of guaranty issued to support such Indebtedness or obligation; provided that the term Guarantee shall not include endorsements for collection or deposit in the ordinary course of business. 

“Guarantors” means all guarantors and all non-Loan Parties who have delivered an
Obligation Guaranty, and the term “Guarantor” means each or any one of them individually. 
 “Hazardous
Materials” means: (a) any substance, material, or waste that is included within the definitions of “hazardous substances,” “hazardous materials,” “hazardous waste,” “toxic substances,”
“toxic materials,” “toxic waste,” or words of similar import in any Environmental Law; (b) those substances listed as hazardous substances by the United States Department of Transportation (or any successor agency) (49
C.F.R. 172.101 and amendments thereto) or by the Environmental Protection Agency (or any successor agency) (40 C.F.R. Part 302 and amendments thereto); and (c) any substance, material, or waste that is petroleum, petroleum-related, or a
petroleum by-product, asbestos or asbestos-containing material, polychlorinated biphenyls, flammable, explosive, radioactive, freon gas, radon, or a pesticide, herbicide, or any other agricultural chemical.

 “Indebtedness” of any Person means, without duplication, (a) all obligations of such Person for borrowed money,
(b) all obligations of such Person evidenced by bonds, debentures, notes or similar instruments, (c) all obligations of such Person upon which interest charges are customarily paid, (d) all obligations of such Person under conditional
sale or other title retention agreements relating to property acquired by such Person, (e) all obligations of such Person in respect of the deferred purchase price of property or services (excluding accounts payable incurred in the ordinary
course of business), (f) all Indebtedness of others secured by (or for which the holder of such Indebtedness has an existing right, contingent or otherwise, to be secured by) any Lien on property owned or acquired by such Person, whether or not
the Indebtedness secured thereby has been assumed, (g) all Guarantees by such Person of Indebtedness of others, (h) all Capital Lease Obligations of such Person, (i) all obligations, contingent or otherwise, of such Person as an
account party in respect of letters of credit and letters of guaranty, (j) all obligations, contingent or otherwise, of such Person in respect of bankers’ acceptances, (k) obligations under any
earn-out (which for all purposes of this Agreement shall be valued at the maximum potential amount payable with respect to each such earn-out), and (l) any other Off-Balance Sheet Liability. The Indebtedness of any Person shall include the Indebtedness of any other entity (including any partnership in which such Person is a general partner) to the extent such Person is
liable therefor as a result of such Person’s ownership interest in or other relationship with such entity, except to the extent the terms of such Indebtedness provide that such Person is not liable therefor. 

“Indemnitee” has the meaning assigned to such term in Section 8.03(b). 

“Information” has the meaning assigned to such term in Section 8.12. 

“Inventory” has the meaning assigned to such term in the Security Agreement. 

“IRS” means the United States Internal Revenue Service. 

“Lender” means JPMorgan Chase Bank, N.A., its successors and assigns. 

“Letters of Credit” means the letters of credit issued pursuant to this Agreement, and the term “Letter of
Credit” means any one of them or each of them singularly, as the context may require. 
 “Lien” means, with
respect to any asset, (a) any mortgage, deed of trust, lien, pledge, hypothecation, encumbrance, charge or security interest in, on or of such asset, (b) the interest of a vendor or a lessor under any conditional sale agreement, capital
lease or title retention agreement (or any financing lease having substantially the same economic effect as any of the foregoing) relating to such asset and (c) in the case of securities, any purchase option, call or similar right of a third
party with respect to such securities. 
 “Loan Documents” means, collectively, this Agreement, each promissory note issued
pursuant to this Agreement, each Collateral Document, any Obligation Guaranty, each Compliance Certificate or other certification delivered in connection with this Agreement, and each other agreement, instrument, document and certificate identified
in Section 4.01 executed and delivered to, or in favor of, Lender and including each other pledge, power of attorney, consent, assignment, contract, notice, letter of credit 

  
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agreement, letter of credit application and each other written matter whether heretofore, now or hereafter executed by or on behalf of any Loan Party, or any employee of any Loan Party, and
delivered to Lender in connection with this Agreement or the transactions contemplated hereby. Any reference in this Agreement or any other Loan Document to a Loan Document shall include all appendices, exhibits or schedules thereto, and all
amendments, restatements, supplements or other modifications thereto, and shall refer to this Agreement or such Loan Document as the same may be in effect at any and all times such reference becomes operative. 

“Loan Parties” means, collectively, Borrowers, a Borrower’s domestic Subsidiaries and any other Person who becomes a
party to this Agreement and their respective successors and assigns, and the term “Loan Party” shall mean any one of them or all of them individually, as the context may require. 

“Loan(s)” means the loan(s) and advance(s) made by Lender pursuant to this Agreement. 

“Margin Stock” means margin stock within the meaning of Regulations T, U and X, as applicable. 

“Material Adverse Effect” means a material adverse effect on (a) the business, assets, operations, or condition,
financial or otherwise, of the any Loan Party, (b) the ability of any Loan Party to perform any of its Obligations, (c) the Collateral, or Lender’s Liens (on behalf of itself and the other Secured Parties) on the Collateral or the
priority of such Liens, or (d) the rights of or benefits available to Lender under any of the Loan Documents. 
 “Material
Indebtedness” means Indebtedness (other than the Loans and Letters of Credit) of any one or more of the Loan Parties in an aggregate principal amount exceeding $250,000. 

“Maximum Rate” has the meaning assigned to such term in Section 8.16. 

“Moody’s” means Moody’s Investors Service, Inc. 

“Net Proceeds” means, with respect to any event, (a) the cash proceeds received in respect of such event including
(i) any cash received in respect of any non-cash proceeds (including any cash payments received by way of deferred payment of principal pursuant to a note or instalment receivable or purchase price
adjustment receivable or otherwise, but excluding any interest payments), but only as and when received, (ii) in the case of a casualty, insurance proceeds and (iii) in the case of a condemnation or similar event, condemnation awards and
similar payments, minus (b) the sum of (i) all reasonable fees and out-of-pocket expenses paid to third parties (other than Affiliates) in connection with such
event, (ii) in the case of a sale, transfer or other disposition of an asset (including pursuant to a sale and leaseback transaction or a casualty or a condemnation or similar proceeding), the amount of all payments required to be made as a
result of such event to repay Indebtedness (other than Loans) secured by such asset or otherwise subject to mandatory prepayment as a result of such event and (iii) the amount of all taxes paid (or reasonably estimated to be payable) and the
amount of any reserves established to fund contingent liabilities reasonably estimated to be payable, in each case during the year that such event occurred or the next succeeding year and that are directly attributable to such event (as determined
reasonably and in good faith by a Financial Officer of Borrower Representative). 
 “Obligation Guaranty” means any
Guarantee of all or any portion of the Secured Obligations executed and delivered to Lender for the benefit of the Secured Parties by a guarantor who is not a Loan Party. 

“Obligations” means all unpaid principal of and accrued and unpaid interest on the Loans, all Letters of Credit, all accrued
and unpaid fees (including, without limitation, any Prepayment Fees), and all expenses, reimbursements, indemnities and other obligations and indebtedness (including interest and fees accruing during the pendency of any bankruptcy, insolvency,
receivership or other similar proceeding, regardless of whether allowed or allowable in such proceeding), obligations and liabilities of any of the Loan Parties to Lender or any indemnified party, individually or collectively, existing on the
Effective Date or arising thereafter, direct or indirect, joint or several, absolute or contingent, matured or unmatured, liquidated or unliquidated, secured or unsecured, arising by contract, operation of law or otherwise, arising or incurred under
this Agreement or any of the other Loan Documents or in respect of any of the Loans made or reimbursement or other obligations incurred or any of the Letters of Credit or other instruments at any time evidencing any thereof. 

“Off-Balance Sheet Liability” of a Person means (a) any repurchase obligation or
liability of such Person with respect to accounts or notes receivable sold by such Person, (b) any indebtedness, liability or obligation under any so-called “synthetic lease” transaction entered
into by such Person, or (c) any indebtedness, liability or obligation arising with respect to any other transaction which is the functional equivalent of or takes the place of borrowing but which does not constitute a liability on the balance
sheet of such Person (other than operating leases). 
 “Paid in Full” or “Payment in Full” means,
(i) the indefeasible payment in full in cash of all outstanding Loans, together with accrued and unpaid interest thereon, (ii) the termination, expiration, or cancellation and return of all outstanding Letters of Credit (or alternatively,
with respect to each such Letter of Credit, the furnishing to Lender of a cash deposit, or at the discretion of Lender a back up standby letter of credit satisfactory to Lender, in an amount equal to 105% of the Letters of Credit as of the date of
such payment), (iii) the indefeasible payment in full in cash of the accrued and unpaid fees, including the applicable Prepayment 

  
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Fee, if any, (iv) the indefeasible payment in full in cash of all reimbursable expenses and other Secured Obligations (other than Unliquidated Obligations for which no claim has been made
and other obligations expressly stated to survive such payment and termination of this Agreement), together with accrued and unpaid interest thereon, (v) the termination of the Term Loan Commitment, and (vi) the termination of the Banking
Services Obligations. 
 “Participant” has the meaning assigned to such term in Section 8.04(c). 

“Participant Register” has the meaning assigned to such term in Section 8.04(c). 

“Permitted Discretion” means a determination made in good faith and in the exercise of reasonable (from the perspective of a
secured lender) business judgment. 
 “Permitted Investments” means: 

(a)    direct obligations of, or obligations the principal of and interest on which are unconditionally
guaranteed by, the U.S. (or by any agency thereof to the extent such obligations are backed by the full faith and credit of the U.S.), in each case maturing within one year from the date of acquisition thereof; 

(b)     investments in commercial paper maturing within 270 days from the date of acquisition thereof and
having, at such date of acquisition, the highest credit rating obtainable from S&P or from Moody’s; 

(c)    investments in certificates of deposit, bankers’ acceptances and time deposits maturing within
180 days from the date of acquisition thereof issued or guaranteed by or placed with, and money market deposit accounts issued or offered by, any domestic office of any commercial bank organized under the laws of the U.S. or any state thereof which
has a combined capital and surplus and undivided profits of not less than $500,000,000; 
 (d)    fully
collateralized repurchase agreements with a term of not more than 30 days for securities described in clause (a) above and entered into with a financial institution satisfying the criteria described in clause (c) above; and 

(e)    money market funds that (i) comply with the criteria set forth in Securities and Exchange
Commission Rule 2a-7 under the Investment Company Act of 1940, (ii) are rated AAA by S&P and Aaa by Moody’s and (iii) have portfolio assets of at least $5,000,000,000. 

“Permitted Licenses” means: (A) licenses of
over-the-counter software that is commercially available to the public, and (B) licenses for the use of the intellectual property of any Borrower or any Subsidiary
entered into in the ordinary course of business, provided, that, with respect to each such license described in clause (B), (i) no Event of Default has occurred and is continuing at the time of such license; (ii) the license constitutes an arms
length transaction, the terms of which, on their face, do not provide for a sale or assignment of any intellectual property and do not restrict the ability of any Borrower or any Subsidiary, as applicable, to pledge, grant a security interest in or
lien on, or assign or otherwise transfer any intellectual property of such Borrower or Subsidiary (other than a requirement that any such pledge, grant of security interest, assignment or transfer be subject to the license); (iii) in the case of any
exclusive license, (x) such granting Borrower delivers written notice in the form of Schedule II to the Compliance Certificate with the next Compliance Certificate to be provided to Lender pursuant to Section 5.01(c), and (y) any such
license could not result in a legal transfer of title of the licensed property but may be exclusive in respects other than territory and may be exclusive as to territory only as to discrete geographical areas outside of the United States; and
(iv) all upfront payments, royalties, milestone payments or other proceeds arising from the licensing agreement that are payable to any Borrower or its Subsidiary are paid to a deposit account at Lender or that is governed by a control
agreement. 
 “Permitted Liens” means: 

(a)    Liens created pursuant to any Loan Document; 

(b)    Liens imposed by law for Taxes that are not yet due or are being contested in compliance with
Section 5.04; 
 (c)    carriers’, warehousemen’s, mechanics’, materialmen’s,
repairmen’s and other like Liens imposed by law, arising in the ordinary course of business and securing obligations that are not overdue by more than thirty (30) days or are being contested in compliance with Section 5.04; 

(d)    Permitted Licenses or sublicenses of intellectual property granted in the ordinary course of a
Borrower’s business; 
 (e)    pledges and deposits made in the ordinary course of business in
compliance with workers’ compensation, unemployment insurance and other social security laws or regulations; 

  
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 (f)    deposits to secure the performance of bids, trade
contracts, leases, statutory obligations, surety and appeal bonds, performance bonds and other obligations of a like nature, in each case in the ordinary course of business; 

(g)    Liens by Pacific Western Bank on certain cash collateral held in each of (i) account no.
xxx-xxxx-366 and (ii) xxx-xxxx-199 at Pacific Western Bank to cash secure the Indebtedness identified in Section 6.01(f) hereof; 

(h)    judgment Liens in respect of judgments that do not constitute an Event of Default under clause
(k) of Article VII; and 
 (i)    easements, zoning restrictions, rights-of-way and similar encumbrances on Real Property imposed by law or arising in the ordinary course of business that do not secure any monetary obligations and do not materially detract from the value of
the affected property or interfere with the ordinary conduct of business of a Borrower or any Subsidiary; 
 provided that the term
“Permitted Liens” shall not include any Lien securing Indebtedness, except with respect to clause (e) above. 

“Person” means any natural person, corporation, limited liability company, trust, joint venture, association, company,
partnership, Governmental Authority or other entity. 
 “Prepayment Fee” means a fee payable to Lender upon the occurrence
of a Prepayment Fee Event, in an amount equal to the outstanding principal balance of the Term Loan at the time of such Prepayment Fee Event multiplied by (a) 2.00% if such Prepayment Fee Event occurs prior to the first anniversary of the Effective
Date, (b) 1.00% if such Prepayment Fee Event occurs on or after the first but prior to the second anniversary of the Effective Date, and (c) 0% if such Prepayment Fee Event occurs on or after the second anniversary of the Effective Date. 

“Prepayment Fee Event” means any repayment or prepayment in whole or in part or acceleration of the Term Loan for any reason
and at any time, including, without limitation, whether such reduction or termination or repayment, prepayment or acceleration is (i) voluntary or mandatory, (ii) made when a Default or Event of Default is then outstanding, (iii) made
in connection with the sale during any Event of Default or foreclosure upon the Collateral, (iv) the result of or subsequent to the acceleration of the Term Loan for any reason at any time, including, without limitation, as a result of the
occurrence of any Event of Default and, in the case of insolvency, reorganization or like proceeding, whether or not a claim for the Prepayment Fee is allowed in such proceeding, (v) made pursuant to, or as the consequence of, any regulatory or
judicial enforcement or other actions from any Governmental Authority, or (vi) made pursuant to, or as the consequence of, any Bankruptcy Event, whether or not a claim for the Prepayment Fee is allowed in such proceeding. 

“Prime Rate” means the rate of interest last quoted by The Wall Street Journal as the “Prime Rate” in the U.S. or,
if The Wall Street Journal ceases to quote such rate, the highest per annum interest rate published by the Federal Reserve Board in Federal Reserve Statistical Release H.15 (519) (Selected Interest Rates) as the “bank prime loan” rate or,
if such rate is no longer quoted therein, any similar rate quoted therein (as determined by Lender) or any similar release by the Federal Reserve Board (as determined by Lender). Each change in the Prime Rate shall be effective from and including
the date such change is publicly announced or quoted as being effective. 
 “Projections” has the meaning assigned to such
term in Section 5.01(e). 
 “Related Parties” means, with respect to any specified Person, such Person’s
Affiliates and the respective directors, officers, partners, members, trustees, employees, agents, administrators, managers, representatives and advisors of such Person and such Person’s Affiliates. 

“Release” means any releasing, spilling, leaking, pumping, pouring, emitting, emptying, discharging, injecting, escaping,
leaching, migrating, disposing, or dumping of any substance into the environment. 
 “Remaining Months Liquidity” means an
aggregate amount of unrestricted cash held in accounts with Lender equal to Borrowers’ trailing three (3) month Cash Burn, measured in accordance with GAAP on a trailing three (3) month basis as of the last day of any fiscal month.

 “Report” means reports prepared by Lender or another Person showing the results of appraisals, field examinations or
audits pertaining to a Borrower’s assets from information furnished by or on behalf of such Borrower, after Lender has exercised its rights of inspection pursuant to this Agreement. 

“Requirement of Law” means, with respect to any Person, (a) the charter, articles or certificate of organization or
incorporation and bylaws or operating, management or partnership agreement, or other organizational or governing documents of such Person and (b) any statute, law (including common law), treaty, rule, regulation, code, ordinance, order, decree,
writ, judgment, injunction or determination of any arbitrator or court or other Governmental Authority (including Environmental Laws), in each case applicable to or binding upon such Person or any of its property or to which such Person or any of
its property is subject. 

  
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 “Responsible Officer” means the CEO, President, CFO, COO, or other
executive officer of a Borrower. 
 “Restricted Payment” means any dividend or other distribution (whether in cash,
securities or other property) with respect to any Equity Interests in any Borrower or any Subsidiary, or any payment (whether in cash, securities or other property), including any sinking fund or similar deposit, on account of the purchase,
redemption, retirement, acquisition, cancellation or termination of any such Equity Interests or any option, warrant or other right to acquire any such Equity Interests. 

“S&P” means Standard & Poor’s Ratings Services, a Standard & Poor’s Financial Services LLC
business. 
 “Sanctioned Country” means, at any time, a country, region or territory which is the subject or target of any
Sanctions (at the time of this Agreement, Crimea, Cuba, Iran, North Korea, and Syria). 
 “Sanctioned Person” means, at any
time, (a) any Person listed in any Sanctions-related list of designated Persons maintained by the Office of Foreign Assets Control of the U.S. Department of the Treasury, the U.S. Department of State, or by the United Nations Security Council,
the European Union, any European Union member state, Her Majesty’s Treasury of the United Kingdom or other relevant sanctions authority, (b) any Person operating, organized or resident in a Sanctioned Country, (c) any Person owned or
controlled by any such Person or Persons described in the foregoing clauses (a) or (b), or (d) any Person otherwise the subject of any Sanctions. 

“Sanctions” means all economic or financial sanctions or trade embargoes imposed, administered or enforced from time to time
by (a) the U.S. government, including those administered by the Office of Foreign Assets Control of the U.S. Department of the Treasury or the U.S. Department of State, or (b) the United Nations Security Council, the European Union, any
European Union member state or Her Majesty’s Treasury of the United Kingdom or other relevant sanctions authority. 

“SEC” means the Securities and Exchange Commission of the U.S. 

“Secured Obligations” means all Obligations, together with all Banking Services Obligations owing to Lender or its
Affiliates. 
 “Secured Parties” means (a) Lender, (b) each provider of Banking Services, to the extent the Banking
Services Obligations in respect thereof constitute Secured Obligations, (c) the beneficiaries of each indemnification obligation undertaken by any Loan Party under any Loan Document, and (d) the successors and assigns of each of the
foregoing. 
 “Security Agreement” means that certain Pledge and Security Agreement (including any and all supplements
thereto), dated as of the date hereof, among the Loan Parties and Lender, for the benefit of the Secured Parties, and any other pledge or security agreement entered into, after the date of this Agreement by any other Loan Party (as required by this
Agreement or any other Loan Document) or any other Person for the benefit of Lender, on behalf of the Secured Parties, as the same may be amended, restated, supplemented or otherwise modified from time to time. 

“Statutory Reserve Rate” means a fraction (expressed as a decimal), the numerator of which is the number one and the
denominator of which is the number one minus the aggregate of the maximum reserve percentage (including any marginal, special, emergency or supplemental reserves) established by the Federal Reserve Board to which the Lender is subject with respect
to the Adjusted LIBO Rate, for eurocurrency funding (currently referred to as “Eurocurrency liabilities” in Regulation D). Such reserve percentages shall include those imposed pursuant to Regulation D of the Federal Reserve Board, The
Statutory Reserve Rate shall be adjusted automatically on and as of the effective date of any change in any reserve percentage. 

“Statements” has the meaning assigned to such term in Section 2.09(d). 

“Subordinated Indebtedness” of a Person means any Indebtedness of such Person, the payment of which is subordinated to
payment of the Obligations to the written satisfaction of Lender. 
 “Subsidiary” means any direct or indirect subsidiary
of a Borrower or a Loan Party, as applicable. 
 “Taxes” means any and all present or future taxes, levies, imposts,
duties, deductions, withholdings (including backup withholding), value added taxes, or any other goods and services, use or sales taxes, assessments, fees or other charges imposed by any Governmental Authority, including any interest, additions to
tax or penalties applicable thereto. 
 “Term Loan” means a Loan made pursuant to Section 2.01. 

  
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 “Term Loan Commitment” means the commitment of Lender to make the Term
Loan, expressed as an amount representing the maximum principal amount of the Term Loan to be made by Lender. The amount of Lender’s Term Loan Commitment on the Effective Date is $15,000,000. 

“Term Loan Maturity Date” is October 1, 2023. 

“Transactions” means the execution, delivery and performance by Borrowers of this Agreement and the other Loan Documents, the
borrowing of Loans and other credit extensions, the use of the proceeds thereof and the issuance of Letters of Credit hereunder. 

“UCC” means the Uniform Commercial Code as in effect from time to time in the State of New York or in any other state, the
laws of which are required to be applied in connection with the issue of perfection of security interests. 
 “Unliquidated
Obligations” means, at any time, any Secured Obligations (or portion thereof) that are contingent in nature or unliquidated at such time, including any Secured Obligation that is: (i) an obligation to reimburse a bank for drawings not
yet made under a Letter of Credit issued by it; (ii) any other obligation (including any guarantee) that is contingent in nature at such time; or (iii) an obligation to provide collateral to secure any of the foregoing types of
obligations. 
 “U.S.” means the United States of America. 

“USA PATRIOT Act” means the Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and
Obstruct Terrorism Act of 2001. 
 SECTION 1.02.    Terms Generally. The definitions of terms herein shall apply
equally to the singular and plural forms of the terms defined. Whenever the context may require, any pronoun shall include the corresponding masculine, feminine and neuter forms. The words “include”, “includes” and
“including” shall be deemed to be followed by the phrase “without limitation”. The word “law” shall be construed as referring to all statutes, rules, regulations, codes and other laws (including official rulings and
interpretations thereunder having the force of law or with which affected Persons customarily comply) and all judgments, orders and decrees of all Governmental Authorities. The word “will” shall be construed to have the same meaning and
effect as the word “shall”. Unless the context requires otherwise (a) any definition of or reference to any agreement, instrument or other document herein shall be construed as referring to such agreement, instrument or other document
as from time to time amended, restated, supplemented or otherwise modified (subject to any restrictions on such amendments, restatements, supplements or modifications set forth herein), (b) any definition of or reference to any statute, rule or
regulation shall be construed as referring thereto as from time to time amended, supplemented or otherwise modified (including by succession of comparable successor laws), (c) any reference herein to any Person shall be construed to include such
Person’s successors and assigns (subject to any restrictions on assignments set forth herein) and, in the case of any Governmental Authority, any other Governmental Authority that shall have succeeded to any or all functions thereof,
(d) the words “herein”, “hereof” and “hereunder”, and words of similar import, shall be construed to refer to this Agreement in its entirety and not to any particular provision hereof, (e) all references
herein to Articles, Sections, Exhibits and Schedules shall be construed to refer to Articles and Sections of, and Exhibits and Schedules to, this Agreement, (f) any reference in any definition to the phrase “at any time” or “for
any period” shall refer to the same time or period for all calculations or determinations within such definition, and (g) the words “asset” and “property” shall be construed to have the same meaning and effect and to
refer to any and all tangible and intangible assets and properties, including cash, securities, accounts and contract rights. 
 SECTION
1.03.    Accounting Terms; GAAP. Except as otherwise expressly provided herein, all terms of an accounting or financial nature shall be construed in accordance with GAAP, as in effect from time to time. 

ARTICLE II 
 The Credits

 SECTION 2.01.    Term Loan. Subject to the terms and conditions set forth herein, on the Effective Date,
or as soon thereafter as all conditions precedent to the making thereof have been met, Lender shall make one (1) Term Loan to Borrowers in the principal amount of Lender’s Term Loan Commitment. Amounts prepaid or repaid in respect of the
Term Loan may not be reborrowed. 
 SECTION 2.02.    Borrowing Procedures; Requests for Term Loans. To request
the Term Loan, Borrower Representative shall notify Lender of such request either in writing (delivered by hand or fax) by delivering a Borrowing Request signed by a Responsible Officer of a Borrower Representative or through an Electronic System,
if arrangements for doing so have been approved by Lender, not later than 12:00 p.m., Eastern time, on the date of the proposed Term Loan. Each such Borrowing Request shall be irrevocable. Each such Borrowing Request shall specify the following
information in compliance with Section 2.01: 
 (a)    the aggregate amount of the requested Term Loan and a
breakdown of the separate wires comprising the Term Loan; and 

  
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 (b)    the date of the Term Loan, which shall be a Business Day. 

SECTION 2.03.    Funding of the Term Loan. Lender shall make the Term Loan to be made by it hereunder on the
proposed date thereof available to Borrowers by promptly crediting the amounts in immediately available funds, to the Funding Account. 

SECTION 2.04.    Termination of the Term Loan Commitment. 

(a)    Unless previously terminated, the Term Loan Commitment shall terminate on the Effective Date, or as soon thereafter
as Lender makes the Term Loan to Borrower. 
 (b)    Borrowers may at any time terminate the Term Loan upon the Payment
in Full of the Secured Obligations. 
 (c)    Borrowers shall notify Lender of any election to terminate the Term Loan
Commitment under paragraph (b) of this Section at least three (3) Business Days prior to the effective date of such termination, specifying such election and the effective date thereof. Each notice delivered by Borrowers pursuant to this
Section shall be irrevocable; provided that a notice of termination of the Term Loan Commitment delivered by Borrowers may state that such notice is conditioned upon the effectiveness of other credit facilities, in which case such notice may
be revoked by Borrowers (by notice to Lender on or prior to the specified effective date) if such condition is not satisfied. Any termination of the Term Loan Commitment shall be permanent and subject to payment of the Prepayment Fee under
Section 2.07. 
 SECTION 2.05.    Repayment and Amortization of Loans; Evidence of Debt.

 (a)    Borrowers hereby unconditionally promise to pay Lender the then unpaid principal amount of the Term Loan
Commitment on the Term Loan Maturity Date. 
 (b)    The Term Loan shall be “interest-only” until
April 25, 2021, with interest due and payable monthly in arrears on the first calendar day of each month pursuant to Section 2.08. Thereafter, Borrowers hereby unconditionally promise to pay to Lender the then unpaid principal amount of
the Term Loan in equal monthly installments of principal plus accrued and unpaid interest beginning on May 1, 2021, and continuing on the same day of each month thereafter; provided, however, if any date set forth above is not a Business Day,
then payment shall be due and payable on the Business Day immediately preceding such date. To the extent not previously paid, the unpaid Term Loan shall be paid in full in cash by Borrowers on the Term Loan Maturity Date. 

(c)    Prior to any repayment of the Term Loan under this Section, Borrowers shall notify Lender by telephone (confirmed
by fax or through an Electronic System) of such election not later than 12:00 p.m., Eastern time, three (3) Business Days before the scheduled date of such repayment. Repayment of the Term Loan shall be applied ratably to the Loans included in
the repaid Term Loan. Repayments of the Term Loan shall be accompanied by accrued interest on the amounts repaid. 
 SECTION
2.06.    Prepayment of Loans. Borrowers shall have the right at any time and from time to time to prepay the Term Loan in whole, subject to prior written notice to Lender of its election to prepay the Term Loan at least
five (5) Business Days prior to such prepayment and, if applicable, payment any Prepayment Fee under Section 2.07. 
 SECTION
2.07.    Fees. Except as set forth in the immediately following sentence, upon the occurrence of a Prepayment Fee Event, Borrowers shall pay to Lender an amount equal to the Prepayment Fee. Notwithstanding the foregoing,
no Prepayment Fee shall be payable in respect of the Term Loan in connection with any amortization payments pursuant to Section 2.05. The parties hereto acknowledge and agree that the Prepayment Fee referred to in the first sentence of this
Section 2.07: (i) is additional consideration for providing the Term Loan, (ii) constitutes reasonable liquidated damages to compensate Lender for (and is a proportionate quantification of) the actual loss of the anticipated stream of
interest payments upon an early prepayment of the Term Loan (such damages being otherwise impossible to ascertain or even estimate for various reasons, including, without limitation, because such damages would depend on, among other things,
(x) when the Term Loan might otherwise be repaid and (y) future changes in interest rates which are not readily ascertainable on the Effective Date), and (iii) is not a penalty to punish Borrowers for their early prepayment of the
Term Loan or for the occurrence of any Event of Default or any other Prepayment Fee Event. 
 All fees payable hereunder shall be paid on the dates due, in
immediately available funds, to Lender. Fees paid shall not be refundable under any circumstances. 
 SECTION
2.08.    Interest. 
 (a)    The Term Loan shall bear interest at the CB Floating Rate plus
one quarter percentage point (0.25%). 

  
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 (b)    Notwithstanding the foregoing, during the occurrence and
continuance of an Event of Default, Lender may, at its option, by written notice to Borrowers, declare that (i) each Term Loan shall bear interest at 5% plus the rate otherwise applicable to the Term Loan as provided in the preceding paragraphs
of this Section or (ii) in the case of any other amount outstanding hereunder, such amount shall accrue at 5% plus the rate applicable to such fee or other obligation as provided hereunder. 

(c)    Accrued interest on each Term Loan through the last day of the prior calendar month shall be payable in arrears on
the first calendar day of each month for the Term Loan; provided that (i) interest accrued pursuant to paragraph (b) of this Section shall be payable on demand, and (ii) in the event of any repayment or prepayment of the Term
Loan, accrued interest on the principal amount repaid or prepaid shall be payable on the date of such repayment or prepayment. 

(d)    All interest hereunder shall be computed on the basis of a year of 365 days (or 366 days in a leap year), and in
each case shall be payable for the actual number of days elapsed (including the first day but excluding the last day). The applicable CB Floating Rate shall be determined by Lender, and such determination shall be conclusive absent manifest error.

 SECTION 2.09.    Payments Generally; Allocation of Proceeds. 

(a)    Borrowers shall make each payment or prepayment required to be made by it hereunder (whether of principal, interest,
fees, or otherwise) prior to 2:00 p.m., Eastern time, on the date when due or the date fixed for any prepayment hereunder, in immediately available funds, without setoff, recoupment or counterclaim. Any amounts received after such time on any date
may, in the discretion of Lender, be deemed to have been received on the next succeeding Business Day for purposes of calculating interest thereon. All such payments shall be made to Lender at its offices at New York, New York. Unless otherwise
provided for herein, if any payment hereunder shall be due on a day that is not a Business Day, the date for payment shall be extended to the next succeeding Business Day, and, in the case of any payment accruing interest, interest thereon shall be
payable for the period of such extension. All payments hereunder shall be made in dollars. 
 (b)    All payments and
any proceeds of Collateral received by Lender (i) not constituting either (A) a specific payment of principal, interest, fees or other sum payable under the Loan Documents (which shall be applied as specified by Borrowers), or (B) a
mandatory prepayment (which shall be applied in accordance with Section 2.09) or (ii) after an Event of Default has occurred and is continuing and Lender so elects, such funds shall be applied ratably first, to pay any fees,
indemnities, or expense reimbursements then due to Lender from Borrowers, second, to pay interest then due and payable on the Loans ratably, third, to prepay principal on the Loans and to pay any amounts owing in respect of Banking
Services Obligations, ratably (with amounts allocated to the Term Loan applied to reduce the subsequent scheduled repayments of the Term Loan to be made pursuant to Section 2.05 in inverse order of maturity), fourth, to pay an amount to
Lender equal to one hundred five percent (105%) of any Letters of Credit, to be held as cash collateral for such Obligations, and fifth, to the payment of any other Secured Obligation due to Lender from Borrowers or any other Loan Party. 

(c)    At the election of Lender, all payments of principal, interest, fees, premiums, reimbursable expenses (including,
without limitation, all reimbursement for fees, costs and expenses pursuant to Section 8.03), and other sums payable under the Loan Documents, may be paid from the proceeds of the Term Loan made hereunder, whether made following a request by
Borrower Representative pursuant to Section 2.02 or a deemed request as provided in this Section or may be deducted from any deposit account of any Borrower maintained with Lender. Borrowers hereby irrevocably authorize Lender to (i) make
the Term Loan for the purpose of paying each payment of principal, interest and fees as it becomes due hereunder or any other amount due under the Loan Documents and agrees that all such amounts charged shall constitute Loans, and that the Term Loan
shall be deemed to have been requested pursuant to Section 2.02 and (ii) charge any deposit account of any Borrower maintained with Lender for each payment of principal, interest and fees as it becomes due hereunder or any other amount due
under the Loan Documents. 
 (d)    Lender may from time to time provide Borrowers with account statements or invoices
with respect to any of the Secured Obligations (the “Statements”). Lender is under no duty or obligation to provide Statements, which, if provided, will be solely for Borrowers’ convenience. Statements may contain estimates of
the amounts owed during the relevant billing period, whether of principal, interest, fees or other Secured Obligations. If Borrowers pay the full amount indicated on a Statement on or before the due date indicated on such Statement, Borrowers shall
not be in default of payment with respect to the billing period indicated on such Statement; provided, that acceptance by Lender of any payment that is less than the total amount actually due at that time (including but not limited to any past due
amounts) shall not constitute a waiver of Lender’s right to receive payment in full at another time. 
 SECTION
2.10.    Returned Payments. If after receipt of any payment which is applied to the payment of all or any part of the Obligations (including a payment effected through exercise of a right of setoff), Lender is for any
reason compelled to surrender such payment or proceeds to any Person because such payment or application of proceeds is invalidated, declared fraudulent, set aside, determined to be void or voidable as a preference, impermissible setoff, or a
diversion of trust funds, or for any other reason (including pursuant to any settlement entered into by Lender in its discretion), then the Obligations or part thereof intended to be satisfied shall be revived and continued and this Agreement shall
continue in full force as if such payment or proceeds had not been received by Lender. The provisions of this Section 2.10 shall be and remain effective notwithstanding any contrary action which may have been taken by Lender in reliance upon
such payment or application of proceeds. The provisions of this Section 2.10 shall survive the termination of this Agreement. 

  
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 ARTICLE III 

Representations and Warranties 

Each Loan Party represents and warrants to Lender that: 

SECTION 3.01.    Organization; Powers. Each Loan Party and each Subsidiary is duly organized or formed, validly
existing and in good standing under the laws of the jurisdiction of its organization, has all requisite power and authority to carry on its business as now conducted and, except where the failure to do so, individually or in the aggregate, could not
reasonably be expected to result in a Material Adverse Effect, is qualified to do business in, and is in good standing in, every jurisdiction where such qualification is required. 

SECTION 3.02.    Authorization; Enforceability. The Transactions are within each Loan Party’s corporate or
other organizational powers and have been duly authorized by all necessary corporate or other organizational actions and, if required, actions by equity holders. Each Loan Document to which each Loan Party is a party has been duly executed and
delivered by such Loan Party and constitutes a legal, valid and binding obligation of such Loan Party, enforceable in accordance with its terms, subject to applicable bankruptcy, insolvency, reorganization, moratorium or other laws affecting
creditors’ rights generally and subject to general principles of equity, regardless of whether considered in a proceeding in equity or at law. 

SECTION 3.03.    Governmental Approvals; No Conflicts. The Transactions (a) do not require any consent or
approval of, registration or filing with, or any other action by, any Governmental Authority, except such as have been obtained or made and are in full force and effect and except for filings necessary to perfect Liens created pursuant to the Loan
Documents, (b) will not violate any Requirement of Law applicable to any Loan Party or any Subsidiary, (c) will not violate or result in a default under any indenture, agreement or other instrument binding upon any Loan Party or any
Subsidiary or the assets of any Loan Party or any Subsidiary, or give rise to a right thereunder to require any payment to be made by any Loan Party or any Subsidiary, and (d) will not result in the creation or imposition of, or other
requirement to create, any Lien on any asset of any Loan Party or any Subsidiary, except Liens created pursuant to the Loan Documents. 

SECTION 3.04.    Financial Condition; No Material Adverse Change. 

(a)    Each Borrower has heretofore furnished to Lender its consolidated balance sheet and statements of income,
stockholders equity and cash flows (i) as of and for the fiscal year ended December 31, 2018, certified by independent public accountants, and (ii) as of and for the fiscal month ended September 30, 2019, certified by a Financial Officer. Such
financial statements present fairly, in all material respects, the financial position and results of operations and cash flows of Borrowers and their consolidated Subsidiaries as of such dates and for such periods in accordance with GAAP, subject to
normal and customary year-end audit adjustments all of which, when taken as a whole, would not be materially adverse and the absence of footnotes in the case of the statements referred to in clause
(ii) above. 
 (b)    No event, change or condition has occurred that has had, or could reasonably be expected to
have, a Material Adverse Effect. 
 SECTION 3.05.    Properties. 

(a)    As of the date of this Agreement, Schedule 3.05 sets forth the address of each parcel of real property that
is owned or leased by any Loan Party. Each of such leases and subleases is valid and enforceable in accordance with its terms (subject to applicable bankruptcy, insolvency, reorganization, moratorium or other laws affecting creditors’ rights
generally and subject to general principles of equity, regardless of whether considered in a proceeding in equity or at law) and is in full force and effect, and, to the knowledge of Borrower, no default by any party to any such lease or sublease
exists. Each of the Loan Parties and each Subsidiary has good and indefeasible title to, or valid leasehold interests in, all of its real and personal property, free of all Liens other than those permitted by Section 6.02. 

(b)    Each Loan Party and each Subsidiary owns, or is licensed to use, all trademarks, tradenames, copyrights, patents
and other intellectual property necessary to its business as currently conducted, a correct and complete list of which, as of the date of this Agreement, is set forth on Schedule 3.05, and the use thereof by each Loan Party and each
Subsidiary does not infringe in any material respect upon the rights of any other Person, and each Loan Party’s and each Subsidiary’s rights thereto are not subject to any licensing agreement or similar arrangement. 

SECTION 3.06.    Litigation. There are no actions, suits or proceedings by or before any arbitrator or Governmental
Authority pending against or, to the knowledge of any Loan Party, threatened against or affecting any Loan Party or any Subsidiary (i) as to which there is a reasonable possibility of an adverse determination and that, if adversely determined,
could reasonably be expected, individually or in the aggregate, to result in a Material Adverse Effect (other than the Disclosed Matters set forth on Schedule 3.06) or (ii) that involve any Loan Document or the Transactions. 

  
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 SECTION 3.07.    Compliance with Laws and Agreements; No Default.
Except where the failure to do so, individually or in the aggregate, could not reasonably be expected to result in a Material Adverse Effect, each Loan Party and each Subsidiary is in compliance with (i) each Requirement of Law applicable to it
or its property and (ii) all indentures, agreements and other instruments binding upon it or its property. No Default has occurred and is continuing. 

SECTION 3.08.    Investment Company Status. No Loan Party or any Subsidiary is an “investment company” as
defined in, or subject to regulation under, the Investment Company Act of 1940. 
 SECTION 3.09.    Taxes. Each
Loan Party and each Subsidiary has timely filed or caused to be filed all Tax returns and reports required to have been filed and has paid or caused to be paid all Taxes required to have been paid by it, except Taxes that (i) in the aggregate
are less than $25,000 or (ii) are being contested in good faith by appropriate proceedings and for which such Loan Party or such Subsidiary, as applicable, has set aside on its books adequate reserves. No tax liens have been filed and no claims
are being asserted by any Governmental Authority with respect to any such taxes. 
 SECTION 3.10.    ERISA. No
ERISA Event has occurred or is reasonably expected to occur that, when taken together with all other such ERISA Events for which liability is reasonably expected to occur, could reasonably be expected to result in a Material Adverse Effect. 

SECTION 3.11.    (a) Disclosure. The Loan Parties have disclosed to Lender all agreements, instruments and
corporate or other restrictions to which any Loan Party or any Subsidiary is subject, and all other matters known to it, that, individually or in the aggregate, could reasonably be expected to result in a Material Adverse Effect. None of the
reports, financial statements, certificates or other information furnished by or on behalf of any Loan Party or any Subsidiary to Lender in connection with the negotiation of this Agreement or any other Loan Document (as modified or supplemented by
other information so furnished) contains any material misstatement of fact or omits to state any material fact necessary to make the statements therein, in the light of the circumstances under which they were made, not misleading; provided
that, with respect to projected financial information, the Loan Parties represent only that such information was prepared in good faith based upon assumptions believed to be reasonable at the time delivered and, if such projected financial
information was delivered prior to the Effective Date, as of the Effective Date. 
 (b)    As of the Effective Date, to
the best knowledge of each Borrower, the information included in the Beneficial Ownership Certification provided on or prior to the Effective Date to Lender in connection with this Agreement is true and correct in all respects. 

SECTION 3.12.    Material Agreements. No Loan Party or any Subsidiary is in default in the performance, observance
or fulfillment of any of the obligations, covenants or conditions contained in (i) any material agreement to which it is a party or (ii) any agreement or instrument evidencing or governing Material Indebtedness. 

SECTION 3.13.    Solvency. Immediately after the consummation of the Transactions to occur on the Effective Date,
(i) the fair value of the assets of each Loan Party, at a fair valuation, will exceed its debts and liabilities, subordinated, contingent or otherwise; (ii) the present fair saleable value of the property of each Loan Party will be greater
than the amount that will be required to pay the probable liability of its debts and other liabilities, subordinated, contingent or otherwise, as such debts and other liabilities become absolute and matured; (iii) each Loan Party will be able
to pay its debts and liabilities, subordinated, contingent or otherwise, as such debts and liabilities become absolute and matured; and (iv) no Loan Party will have unreasonably small capital with which to conduct the business in which it is
engaged as such business is now conducted and is proposed to be conducted after the Effective Date. 
 SECTION
3.14.    Insurance. Schedule 3.14 sets forth a description of all insurance maintained by or on behalf of the Loan Parties and their Subsidiaries as of the Effective Date. As of the Effective
Date, all premiums in respect of such insurance have been paid. The Loan Parties believe that the insurance maintained by or on behalf of the Loan Parties and their Subsidiaries is adequate and is customary for companies engaged in the same or
similar businesses operating in the same or similar locations. 
 SECTION 3.15.    Capitalization and
Subsidiaries. Schedule 3.15 sets forth (a) a correct and complete list of the name and relationship to Borrowers of each Subsidiary, (b) a true and complete listing of each class of each of Borrowers’ authorized Equity
Interests, of which all of such issued Equity Interests are validly issued, outstanding, fully paid and non-assessable, and owned beneficially and of record by the Persons identified on Schedule 3.15,
and (c) the type of entity of each Borrower and each Subsidiary. All of the issued and outstanding Equity Interests owned by any Loan Party have been (to the extent such concepts are relevant with respect to such ownership interests) duly
authorized and issued and are fully paid and non-assessable. 
 SECTION
3.16.    Security Interest in Collateral. The provisions of this Agreement and the other Loan Documents create legal and valid Liens on all the Collateral in favor of Lender, for the benefit of the Secured Parties, and
such Liens constitute perfected and continuing Liens on the Collateral, securing the Secured Obligations, enforceable against the applicable Loan Party and all third parties in accordance with applicable law, and having priority over all other Liens
on the Collateral except in the case 

  
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of (a) Permitted Liens, to the extent any such Permitted Liens would have priority over the Liens in favor of Lender pursuant to any applicable law or agreement and (b) Liens perfected
only by possession (including possession of any certificate of title), to the extent Lender has not obtained or does not maintain possession of such Collateral. 

SECTION 3.17.    Margin Regulations. No Loan Party is engaged and will not engage, principally or as one of its
important activities, in the business of purchasing or carrying Margin Stock, or extending credit for the purpose of purchasing or carrying Margin Stock, and no part of the proceeds of the Loans will be used to purchase or carry any Margin Stock.

 SECTION 3.18.    Use of Proceeds. The proceeds of the Loans will be used, whether directly or indirectly, as
set forth in Section 5.08. 
 SECTION 3.19.    Affiliate Transactions. Except as set forth on Schedule
3.19, as of the date of this Agreement, there are no existing or proposed agreements, arrangements, understandings or transactions between any Loan Party and any of the officers, members, managers, directors, stockholders, parents, holders of
other Equity Interests, employees or Affiliates (other than Subsidiaries) of any Loan Party or any members of their respective immediate families, and none of the foregoing Persons are directly or indirectly indebted to or have any direct or
indirect ownership, partnership, or voting interest in any Affiliate of any Loan Party or any Person with which any Loan Party has a business relationship or which competes with any Loan Party. 

SECTION 3.20.    Anti-Corruption Laws and Sanctions. Each Loan Party has implemented and maintains in effect
policies and procedures designed to ensure compliance by such Loan Party, its Subsidiaries and their respective directors, officers, employees and agents with Anti-Corruption Laws and applicable Sanctions, and such Loan Party, its Subsidiaries and
their respective officers and directors and to the knowledge of such Loan Party its employees and agents, are in compliance with Anti-Corruption Laws and applicable Sanctions in all material respects and are not knowingly engaged in any activity
that would reasonably be expected to result in any Loan Party being designated as a Sanctioned Person. None of (a) any Loan Party, any Subsidiary, any of their respective directors or officers or, to the knowledge of any such Loan Party or
Subsidiary, employees, or (b) to the knowledge of any such Loan Party or Subsidiary, any agent of such Loan Party or any Subsidiary that will act in any capacity in connection with or benefit from the credit facility established hereby, is a
Sanctioned Person. No Term Loan, Letter of Credit, use of proceeds, Transaction, or other transaction contemplated by this Agreement or the other Loan Documents will violate Anti-Corruption Laws or applicable Sanctions. 

ARTICLE IV 
 Conditions

 SECTION 4.01.    Effective Date. The obligations of Lender to make Loans and to issue Letters of Credit
hereunder shall not become effective until the date on which each of the following conditions is satisfied (or waived in accordance with Section 8.02): 

(a)    Credit Agreement and Loan Documents. Lender (or its counsel) shall have received (i) from each party
hereto either (A) a counterpart of this Agreement signed on behalf of such party or (B) written evidence satisfactory to Lender (which may include fax or other electronic transmission of a signed signature page of this Agreement) that such
party has signed a counterpart of this Agreement and (ii) duly executed copies of the Loan Documents and such other certificates, documents, instruments and agreements as Lender shall have reasonably requested in connection with the
transactions contemplated by this Agreement and the other Loan Documents, all in form and substance satisfactory to Lender. 

(b)    Financial Statements and Projections. Lender shall have received (i) audited consolidated financial
statements of each Borrower for the 2018 fiscal year, (ii) unaudited interim consolidated financial statements of each Borrower for the fiscal month ended September 30, 2019. 

(c)    Closing Certificates; Certified Certificate of Incorporation; Good Standing Certificates. Lender shall have
received (i) a certificate of each Loan Party, dated the Effective Date and executed by its Secretary or Assistant Secretary, which shall (A) certify the resolutions of its board of directors, members or other body authorizing the
execution, delivery and performance of the Loan Documents to which it is a party, (B) identify by name and title and bear the signatures of the officers of such Loan Party authorized to sign the Loan Documents to which it is a party and, in the
case of each Borrower, its Financial Officers, and (C) contain appropriate attachments, including the charter, articles or certificate of organization or incorporation of each Loan Party certified by the relevant authority of the jurisdiction
of organization of such Loan Party and a true and correct copy of its bylaws or operating, management or partnership agreement, or other organizational or governing documents, and (ii) a long form good standing certificate for each Loan Party
from its jurisdiction of organization. 
 (d)    No Default Certificate. Lender shall have received a
certificate, signed by a Financial Officer of each Borrower, dated as of the Effective Date, (i) stating that no Default has occurred and is continuing, (ii) stating that the representations and warranties contained in the Loan Documents
are true and correct as of such date, and (iii) certifying as to any other factual matters as may be reasonably requested by Lender. 

  
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 (e)    Fees. Lender shall have received all fees required to be
paid, and all expenses required to be reimbursed for which invoices have been presented (including the reasonable fees and expenses of legal counsel), on or before the Effective Date. All such amounts will be paid with proceeds of Loans made on the
Effective Date and will be reflected in the funding instructions given by Borrower Representative to Lender on or before the Effective Date. 

(f)    Lien Searches. Lender shall have received the results of a recent lien search in the jurisdiction of
organization of each Loan Party and each jurisdiction where assets of the Loan Parties are located, and such search shall reveal no Liens on any of the assets of each of the Loan Parties except for liens permitted by Section 6.02 or discharged
on or prior to the Effective Date pursuant to a pay-off letter or other documentation satisfactory to Lender. 

(g)    Pay-off Letter. Lender shall have received satisfactory pay-off letters for all existing Indebtedness, including, without limitation, Borrowers’ credit facility with Pacific Western Bank, required to be repaid and which confirms that all Liens upon any of the
property of the Loan Parties constituting Collateral will be terminated concurrently with such payment and all letters of credit issued or guaranteed as part of such Indebtedness shall have been cash collateralized or supported by a Letter of
Credit. 
 (h)    Funding Account. Lender shall have received a notice setting forth the deposit account of
Borrowers (the “Funding Account”) to which Lender is authorized by Borrowers to transfer the proceeds of the Term Loan requested or authorized pursuant to this Agreement. 

(i)    Collateral Access and Control Agreements. Lender shall have received each of (i) a Collateral Access
Agreement required to be provided pursuant the Security Agreement and (ii) a deposit account control agreement required to be provided pursuant to the Security Agreement. 

(j)    Solvency. Lender shall have received a solvency certificate signed by a Financial Officer dated the
Effective Date in form and substance reasonably satisfactory to Lender. 
 (k)    Filings, Registrations and
Recordings. Each document (including any Uniform Commercial Code financing statement) required by the Collateral Documents or under law or reasonably requested by Lender to be filed, registered or recorded in order to create in favor of
Lender, for the benefit of the Secured Parties, a perfected Lien on the Collateral described therein, prior and superior in right to any other Person (other than with respect to Liens expressly permitted by Section 6.02), shall be in proper
form for filing, registration or recordation. 
 (l)    Insurance. Lender shall have received evidence of
insurance coverage in form, scope, and substance reasonably satisfactory to Lender and otherwise in compliance with the terms of (i) Section 5.10 of this Agreement and (ii) Section 4.12 of the Security Agreement. 

(m)    Legal Due Diligence. Lender and its counsel shall have completed all legal due diligence, the results of
which shall be satisfactory to Lender in its sole discretion. 
 (n)    USA PATRIOT Act, Etc. (i) Lender
shall have received, (x) at least five (5) days prior to the Effective Date, all documentation and other information regarding Borrowers requested in connection with applicable “know your customer” and anti-money laundering rules
and regulations, including the USA PATRIOT Act, to the extent requested in writing of Borrowers at least ten (10) days prior to the Effective Date, and (y) a properly completed and signed IRS Form
W-8 or W-9, as applicable, for each Loan Party, and (ii) Lender shall have received, to the extent each Borrower qualifies as a “legal entity customer”
under the Beneficial Ownership Regulation, a Beneficial Ownership Certification in relation to Borrowers at least five (5) days prior to the Effective Date, to the extent requested in writing of Borrowers at least ten (10) days prior to
the Effective Date. 
 (o)    Other Documents. Lender shall have received such other documents as Lender or its
counsel may have reasonably requested. 
 Lender shall notify Borrowers of the Effective Date, and such notice shall be conclusive and
binding. Notwithstanding the foregoing, the obligations of Lender to make Loans and to issue Letters of Credit hereunder shall not become effective unless each of the foregoing conditions is satisfied (or waived pursuant to Section 8.02) at or
prior to 2:00 p.m., Eastern time, on the applicable date. 
 SECTION 4.02.    Each Credit Event. The obligation
of Lender to make a Loan on the occasion of the Term Loan, and to issue, amend, renew or extend any Letter of Credit, is subject to the satisfaction of the following conditions: 

(a)    The representations and warranties of the Loan Parties set forth in the Loan Documents shall be true and correct in
all material respects with the same effect as though made on and as of the date of the Term Loan or the date of issuance, amendment, renewal or extension of any Letter of Credit, as applicable (it being understood and agreed that any representation
or warranty which by its terms is made as of a specified date shall be required to be true and correct in all material respects only as of such specified date). 

  
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 (b)    At the time of and immediately after giving effect to the Term
Loan or the issuance, amendment, renewal or extension of such Letter of Credit, as applicable, no Default shall have occurred and be continuing. 

(c)    No event shall have occurred and no condition shall exist which has or could be reasonably expected to have a
Material Adverse Effect. 
 Each Term Loan and each issuance, amendment, renewal or extension of a Letter of Credit shall be deemed to
constitute representations and warranties by each Borrower on the date thereof as to the matters specified above. 
 SECTION
4.03.    Post-Closing Conditions. 
 (a)    As soon as possible, but in any event not later
than the date that is 60 days after the Effective Date, Borrowers shall provide Bank with additional insured and lender’s loss payee endorsements, pursuant to Section 4.12 of the Security Agreement. 

(b)    As soon as possible, but in any event not later than the date that is 60 days after the Effective Date, Borrowers
shall provide Bank with a Collateral Access Agreement from the lessor of each leased property, mortgagee of owned property or bailee or consignee with respect to any warehouse, processor or converter facility or other location where Collateral
valued in excess of $250,000 is stored or located, which agreement or letter shall provide access rights, contain a waiver or subordination of all Liens or claims that the landlord, mortgagee, bailee or consignee may assert against the Collateral at
that location, and shall otherwise be reasonably satisfactory in form and substance to Lender; provided, however, notwithstanding the foregoing, Borrowers shall not be required to deliver to Bank a Collateral Access Agreement for Borrowers’
leased location at 18 Crosby Drive, Bedford, MA 01730. 
 ARTICLE V 

Affirmative Covenants 

Until all of the Secured Obligations shall have been Paid in Full, each Loan Party executing this Agreement covenants and agrees, jointly and
severally with all of the other Loan Parties, with Lender that: 
 SECTION 5.01.    Financial Statements and Other
Information. Borrowers will furnish to Lender: 
 (a)    within 120 days after the end of each fiscal year of each
Borrower, its audited consolidated balance sheet and related statements of operations, stockholders’ equity and cash flows as of the end of and for such year, setting forth in each case in comparative form the figures for the previous fiscal
year, all reported on by independent public accountants acceptable to Lender (without a “going concern” or like qualification, commentary or exception, and without any qualification or exception as to the scope of such audit) to the effect
that such consolidated financial statements present fairly in all material respects the financial condition and results of operations of each Borrower and its consolidated Subsidiaries on a consolidated basis in accordance with GAAP consistently
applied; 
 (b)    within 30 days after the end of each fiscal month of each Borrower, its consolidated and, applicable,
consolidating balance sheet and related statements of operations, stockholders’ equity and cash flows as of the end of and for such fiscal month and the then elapsed portion of the fiscal year, setting forth in each case in comparative form the
figures for the corresponding period or periods of (or, in the case of the balance sheet, as of the end of) the previous fiscal year, all certified by a Financial Officer of Borrower Representative as presenting fairly in all material respects the
financial condition and results of operations of each Borrower and its consolidated Subsidiaries on a consolidated basis in accordance with GAAP consistently applied, subject to normal year-end audit
adjustments and the absence of footnotes; 
 (c)    concurrently with any delivery of financial statements under clause
(a) or (b) above, a compliance certificate of a Financial Officer of Borrower Representative in substantially the form of Exhibit A (the “Compliance Certificate”) (i) certifying, in the case of the financial
statements delivered under clause (a) or (b) above, as presenting fairly in all material respects the financial condition and results of operations of each Borrower and its consolidated Subsidiaries on a consolidated basis in accordance
with GAAP consistently applied, subject to normal year-end audit adjustments and the absence of footnotes, (ii) certifying as to whether a Default has occurred is continuing, and, if a Default has
occurred and is continuing, specifying the details thereof and any action taken or proposed to be taken with respect thereto, (iii) setting forth reasonably detailed calculations demonstrating compliance with Section 6.10, and
(iv) stating whether any change in GAAP or in the application thereof has occurred since the date of the audited financial statements referred to in Section 3.04 and, if any such change has occurred, specifying the effect of such change on
the financial statements accompanying such certificate; 
 (d)    reserved; 

(e)    as soon as available, but in any event no later than 30 days after the end of each fiscal year of each Borrower, a
copy of the board of directors’ approved plan and forecast (including a projected consolidated and consolidating balance sheet, income statement and cash flow statement) of each Borrower for each month of the upcoming fiscal year (the
“Projections”) in form reasonably satisfactory to Lender; 

  
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 (f)    promptly following any request therefor, copies of any detailed
audit reports, management letters or recommendations submitted to the board of directors (or the audit committee of the board of directors) of any Borrower by independent accountants in connection with the accounts or books of any Borrower or any
Subsidiary, or any audit of any of them as Lender may reasonably request; and 
 (g)    promptly following any request
therefor, (x) such other information regarding the operations, changes in ownership of Equity Interests, business affairs and financial condition of any Loan Party or any Subsidiary, or compliance with the terms of this Agreement, as Lender may
reasonably request and (y) information and documentation reasonably requested by Lender for purposes of compliance with applicable “know your customer” and anti-money laundering rules and regulations, including the USA PATRIOT Act and
the Beneficial Ownership Regulation. 
 SECTION 5.02.    Notices of Material Events. Borrower Representative will
furnish to Lender prompt (but in any event within any time period that may be specified below) written notice of the following: 

(a)    the occurrence of any Default; 

(b)    receipt of any notice of any investigation by a Governmental Authority or any litigation or proceeding commenced or
threatened against any Loan Party or any Subsidiary that (i) seeks damages in excess of $250,000, (ii) seeks injunctive relief, (iii) is asserted or instituted against any Plan, its fiduciaries or its assets, (iv) alleges criminal
misconduct by any Loan Party or any Subsidiary, (v) alleges the violation of, or seeks to impose remedies under any Environmental Law or related Requirement of Law, or seeks to impose Environmental Liability, (vi) asserts liability on the
part of any Loan Party or any Subsidiary in excess of $250,000 in respect of any tax, fee, assessment, or other governmental charge, or (vii) involves any product recall; 

(c)    any material change in accounting or financial reporting practices by any Borrower or any Subsidiary; 

(d)    the occurrence of any ERISA Event that, alone or together with any other ERISA Events that have occurred, could
reasonably be expected to result in liability of the Loan Parties and their Subsidiaries in an aggregate amount exceeding $250,000; and 

(e)    any change in the information provided in the Beneficial Ownership Certification delivered to such Lender that
would result in a change to the list of beneficial owners identified in such certification. 
 Each notice delivered under this Section
shall be accompanied by a statement of a Financial Officer or other executive officer of Borrower Representative setting forth the details of the event or development requiring such notice and any action taken or proposed to be taken with respect
thereto. 
 SECTION 5.03.    Existence; Conduct of Business. Each Loan Party will, and will cause each Subsidiary
to, (a) do or cause to be done all things necessary to preserve, renew and keep in full force and effect its legal existence and the rights, qualifications, licenses, permits, franchises, governmental authorizations, intellectual property
rights, licenses and permits necessary for the conduct of its business, and maintain all requisite authority to conduct its business in each jurisdiction in which its business is conducted; provided that the foregoing shall not prohibit any
merger, consolidation, liquidation or dissolution permitted under Section 6.03 and (b) carry on and conduct its business in substantially the same manner and in substantially the same fields of enterprise as it is presently conducted. 

SECTION 5.04.    Payment of Obligations. Each Loan Party will, and will cause each Subsidiary to, pay or discharge
all Material Indebtedness and all other material liabilities and obligations, including Taxes, before the same shall become delinquent or in default, except where (a) the validity or amount thereof is being contested in good faith by
appropriate proceedings, (b) such Loan Party or Subsidiary has set aside on its books adequate reserves with respect thereto in accordance with GAAP and (c) the failure to make payment pending such contest could not reasonably be expected
to result in a Material Adverse Effect; provided, however, that each Loan Party will, and will cause each Subsidiary to, remit withholding taxes and other payroll taxes to appropriate Governmental Authorities as and when claimed to be
due, notwithstanding the foregoing exceptions. 
 SECTION 5.05.    Maintenance of Properties. Each Loan Party
will, and will cause each Subsidiary to, keep and maintain all property necessary for the conduct of its business in good working order and condition, ordinary wear and tear excepted. 

SECTION 5.06.    Books and Records; Inspection Rights. Each Loan Party will, and will cause each Subsidiary to,
(a) keep proper books of record and account in which full, true and correct entries are made of all dealings and transactions in relation to its business and activities and (b) permit any representatives designated by Lender (including
employees of Lender or any consultants, accountants, lawyers, agents and appraisers retained by Lender), upon reasonable prior notice and during regular 

  
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business hours, to visit and inspect its properties, conduct at the Loan Party’s premises field examinations of the Loan Party’s assets, liabilities, books and records, including
examining and making extracts from its books and records, environmental assessment reports and Phase I or Phase II studies, and to discuss its affairs, finances and condition with its officers and independent accountants, all at such reasonable
times and as often as reasonably requested. The Loan Parties acknowledge that Lender, after exercising its rights of inspection, may prepare certain Reports pertaining to the Loan Parties’ assets for internal use by Lender. 

SECTION 5.07.    Compliance with Laws and Material Contractual Obligations. Each Loan Party will, and will cause
each Subsidiary to, (i) comply in all material respects with each Requirement of Law applicable to it or its property (including, without limitation, Environmental Laws) and (ii) perform in all material respects its obligations under
material agreements to which it is a party. Each Loan Party will maintain in effect and enforce policies and procedures designed to ensure compliance by such Loan Party, its Subsidiaries and their respective directors, officers, employees and agents
with Anti-Corruption Laws and applicable Sanctions. 
 SECTION 5.08.    Use of Proceeds. 

(a)    The proceeds of the Loans will be used only for refinancing existing Indebtedness, working capital and general
corporate purposes. No part of the proceeds of any Loan and no Letter of Credit will be used, whether directly or indirectly, (i) for any purpose that entails a violation of any of the regulations of the Federal Reserve Board, including
Regulations T, U and X or (ii) to make any Acquisition. 
 (b)    Borrowers will not request the Term Loan or
Letter of Credit, and no Borrower shall use, and shall procure that its Subsidiaries and its or their respective directors, officers, employees and agents shall not use, the proceeds of the Term Loan or Letter of Credit (a) in furtherance of an
offer, payment, promise to pay, or authorization of the payment or giving of money, or anything else of value, to any Person in violation of any Anti-Corruption Laws, (b) for the purpose of funding, financing or facilitating any activities,
business or transaction of or with any Sanctioned Person, or in any Sanctioned Country, except to the extent permitted for a Person required to comply with Sanctions, or (c) in any manner that would result in the violation of any Sanctions
applicable to any party hereto. 
 SECTION 5.09.    Accuracy of Information. The Loan Parties will ensure that
any information, including financial statements or other documents, furnished to Lender in connection with this Agreement or any other Loan Document or any amendment or modification hereof or thereof or waiver hereunder or thereunder contains no
material misstatement of fact or omits to state any material fact necessary to make the statements therein, in the light of the circumstances under which they were made, not misleading, and the furnishing of such information shall be deemed to be a
representation and warranty by each Borrower on the date thereof as to the matters specified in this Section 5.09; provided that, with respect to the Projections, the Loan Parties will cause the Projections to be prepared in good faith based
upon assumptions believed to be reasonable at the time. 
 SECTION 5.10.    Insurance. Each Loan Party will, and
will cause each Subsidiary to, maintain with financially sound and reputable carriers having a financial strength rating of at least A- by A.M. Best Company (a) insurance in such amounts (with no greater
risk retention) and against such risks (including, without limitation, loss or damage by fire and loss in transit; theft, burglary, pilferage, larceny, embezzlement, and other criminal activities; business interruption; and general liability) and
such other hazards, as is customarily maintained by companies of established repute engaged in the same or similar businesses operating in the same or similar locations and (b) all insurance required pursuant to the Collateral Documents.
Borrowers will furnish to Lender information in reasonable detail as to the insurance so maintained. 
 SECTION
5.11.    Intentionally Omitted. 
 SECTION 5.12.    Casualty and Condemnation.
Borrowers (a) will furnish to Lender prompt written notice of any casualty or other insured damage to any material portion of the Collateral or the commencement of any action or proceeding for the taking of any material portion of the
Collateral or interest therein under power of eminent domain or by condemnation or similar proceeding and (b) will ensure that the Net Proceeds of any such event (whether in the form of insurance proceeds, condemnation awards or otherwise) are
collected and applied to repair or replace the affected property or in accordance with the applicable provisions of this Agreement and the Collateral Documents. 

SECTION 5.13.    Depository Banks. Within 60 days of the Effective Date, each Loan Party and each Subsidiary,
including, for the avoidance of doubt, any Subsidiary that is a “Security Corporation” as defined in 830 Code of Mass. Regulations 63.38B.1 (as the same may be amended, modified or supplemented from time to time), will maintain Lender as
its principal depository bank, including for the maintenance of operating, administrative, cash management, collection activity, and other deposit accounts for the conduct of its business. Notwithstanding the above, Borrowers shall be permitted to
maintain (i) cash and/or investments in its accounts numbered xxx-xxxxx6-428 and
xxx-xxxxx1-428 at Morgan Stanley Asset Management so long as (y) the aggregate amount of cash and/or investments maintained in all accounts with Lender or
Lender’s Affiliates equals or exceeds $30,000,000, and (z) Borrowers cause Morgan Stanley Asset Management to execute and deliver to Lender control agreement(s), satisfactory to Lender in its reasonable business judgment, covering such
accounts, and (ii) cash in all such accounts does not, at any time, exceed $20,000. 

  
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 SECTION 5.14.    Additional Collateral; Further Assurances. 

(a)    Subject to any applicable Requirement of Law, each Loan Party will cause each of its domestic Subsidiaries formed or
acquired after the date of this Agreement or any limited liability companies formed pursuant to any division to become a Loan Party by executing a joinder to this Agreement. In connection therewith, Lender shall have received all documentation and
other information regarding such newly formed or acquired Subsidiaries as may be required to comply with the applicable “know your customer” rules and regulations, including the USA Patriot Act. Upon execution and delivery thereof, each
such Person (i) shall automatically become a Guarantor hereunder and thereupon shall have all of the rights, benefits, duties, and obligations in such capacity under the Loan Documents and (ii) will grant Liens to Lender, for the benefit
of the Secured Parties, in any property of such Loan Party which constitutes Collateral, including any parcel of real property located in the U.S. owned by any Loan Party. 

(b)    Each Loan Party will cause (i) 100% of the issued and outstanding Equity Interests of each of its domestic
Subsidiaries and (ii) 65% of the issued and outstanding Equity Interests entitled to vote (within the meaning of Treas. Reg. Section 1.956-2(c)(2)) and 100% of the issued and outstanding Equity Interests
not entitled to vote (within the meaning of Treas. Reg. Section 1.956-2(c)(2)) in each foreign Subsidiary directly owned by any Borrower or any domestic Subsidiary to be subject at all times to a first
priority, perfected Lien in favor of Lender, for the benefit of the Secured Parties, pursuant to the terms and conditions of the Loan Documents or other security documents as Lender shall reasonably request. 

(c)    Borrowers shall pledge and grant a first priority, perfected Lien in favor of Lender in 100% of the issued and
outstanding Equity Interests of their Subsidiaries. 
 (d)    Without limiting the foregoing, each Loan Party will, and
will cause each domestic Subsidiary to, execute and deliver, or cause to be executed and delivered, to Lender such documents, agreements and instruments, and will take or cause to be taken such further actions (including the filing and recording of
financing statements, fixture filings, mortgages, deeds of trust and other documents and such other actions or deliveries of the type required by Section 4.01, as applicable), which may be required by any Requirement of Law or which Lender may,
from time to time, reasonably request to carry out the terms and conditions of this Agreement and the other Loan Documents and to ensure perfection and priority of the Liens created or intended to be created by the Collateral Documents, all in form
and substance reasonably satisfactory to Lender and all at the expense of the Loan Parties. 
 (e)    If any material
assets (including any real property or improvements thereto or any interest therein) are acquired by any Loan Party after the Effective Date (other than assets constituting Collateral under the Security Agreement that become subject to the Lien
under the Security Agreement upon acquisition thereof), Borrower Representative will (i) notify Lender and, if requested by Lender, cause such assets to be subjected to a Lien securing the Secured Obligations and (ii) take, and cause each
applicable Loan Party to take, such actions as shall be necessary or reasonably requested by Lender to grant and perfect such Liens, including actions described in paragraph (c) of this Section, all at the expense of the Loan Parties. 

ARTICLE VI 
 Negative Covenants

 Until all of the Secured Obligations shall have been Paid in Full, each Loan Party executing this Agreement covenants and agrees,
jointly and severally with all of the other Loan Parties, with Lender that: 
 SECTION 6.01.    Indebtedness. No
Loan Party will, nor will it permit any Subsidiary to, create, incur, assume or suffer to exist any Indebtedness, except: 

(a)    the Secured Obligations; 

(b)    Indebtedness existing on the date hereof and set forth in Schedule 6.01 and any
extensions, renewals, refinancings and replacements of any such Indebtedness; 
 (c)    Indebtedness of a Loan Party to
another Loan Party; 
 (d)    Indebtedness owed to any Person providing workers’ compensation, health, disability
or other employee benefits or property, casualty or liability insurance, pursuant to reimbursement or indemnification obligations to such Person, in each case incurred in the ordinary course of business; 

(e)    Indebtedness of any Loan Party in respect of performance bonds, bid bonds, appeal bonds, surety bonds and similar
obligations, in each case provided in the ordinary course of business; 
 (f)    from the Effective Date through
November 25, 2019, Indebtedness owing from Borrowers to Pacific Western Bank in connection with (i) that certain letter of credit no. 102267 issued by Pacific Western Bank at the request of Borrowers in an aggregate amount not to exceed
$117,156.33, and (ii) that certain letter of credit no. 107121 issued by Pacific Western Bank at the request of Borrowers in an aggregate amount not to exceed $2,057,658.75; 

  
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 (g)    Subordinated Indebtedness; and 

(h)    purchase money Indebtedness of any Loan Party in an amount not to exceed $500,000 in the aggregate at any time.

 SECTION 6.02.    Liens. Except for Liens in existence on the Effective Date and described in Schedule
6.02 hereof, no Loan Party will, nor will it permit any Subsidiary to, create, incur, assume or permit to exist any Lien on any property or asset now owned or hereafter acquired by it, or assign or sell any income or revenues (including
Accounts) or rights in respect of any thereof, except Permitted Liens. 
 SECTION 6.03.    Fundamental Changes.

 (a)    No Loan Party will, nor will it permit any Subsidiary to, merge into or consolidate with any other Person, or
permit any other Person to merge into or consolidate with it, or otherwise Dispose of all or any material part of its assets (except as permitted under Section 6.05), or all or substantially all of the stock of any of its Subsidiaries (in each
case, whether now owned or hereafter acquired), or liquidate, divide or dissolve, except that, if at the time thereof and immediately after giving effect thereto no Event of Default shall have occurred and be continuing, (i) any Subsidiary of
any Borrower may merge into a Borrower in a transaction in which such Borrower is the surviving entity, (ii) any Loan Party (other than any Borrower) may merge into any other Loan Party in a transaction in which the surviving entity is a Loan
Party and (iii) any Subsidiary that is not a Loan Party may liquidate, divide or dissolve if Borrowers determine in good faith that such liquidation, division or dissolution is in the best interests of Borrowers and is not materially
disadvantageous to Lender; provided that any such merger involving a Person that is not a wholly owned Subsidiary immediately prior to such merger shall not be permitted unless also permitted by Section 6.04. 

(b)    No Loan Party will, nor will it permit any Subsidiary to, consummate a Division as the Dividing Person, without the
prior written consent of Lender, which consent shall not be unreasonably withheld. Without limiting the foregoing, if any Loan Party that is a limited liability company consummates a Division (with or without the prior consent of Lender as required
above), each Division Successor shall be required to comply with the obligations set forth in Section 5.14 and the other further assurances obligations set forth in the Loan Documents and become a Loan Party under this Agreement and the other
Loan Documents. 
 (c)    No Loan Party will, nor will it permit any Subsidiary to, engage in any business other than
businesses of the type conducted by Borrowers and their Subsidiaries on the date hereof and businesses reasonably related thereto. 

SECTION 6.04.    Investments, Loans, Advances, Guarantees and Acquisitions. No Loan Party will, nor will it permit
any Subsidiary to, form any subsidiary after the Effective Date, or purchase, hold or acquire (including pursuant to any merger with any Person that was not a Loan Party and a wholly owned Subsidiary prior to such merger) any Equity Interests,
evidences of indebtedness or other securities (including any option, warrant or other right to acquire any of the foregoing) of, make or permit to exist any loans or advances to, Guarantee any obligations of, or make or permit to exist any
investment or any other interest in, any other Person, or purchase or otherwise acquire (in one transaction or a series of transactions) any assets of any other Person constituting a business unit (whether through purchase of assets, merger or
otherwise), except: 
 (a)    Permitted Investments, subject to control agreements in favor of Lender or otherwise
subject to a perfected security interest in favor of Lender; 
 (b)    investments in existence on the date hereof and
described in Schedule 6.04; 
 (c)    investments by Borrowers and their Subsidiaries in Equity Interests in
their respective Subsidiaries, provided that (i) any such Equity Interests held by a Loan Party shall be pledged pursuant to the Security Agreement (subject to the limitations applicable to Equity Interests of a foreign Subsidiary referred to
in Section 5.14) and (ii) the aggregate amount of investments by Loan Parties in Subsidiaries that are not Loan Parties (together with outstanding intercompany loans permitted under Section 6.04(d)) shall not exceed $250,000 at any
time outstanding (in each case determined without regard to any write-downs or write-offs); 
 (d)    loans or advances
made by any Loan Party to any Subsidiary and made by any Subsidiary to a Loan Party or any other Subsidiary, provided that (i) any such loans and advances made by a Loan Party shall be evidenced by a promissory note pledged pursuant to the
Security Agreement and (ii) the amount of such loans and advances made by Loan Parties to Subsidiaries that are not Loan Parties (together with outstanding investments permitted under Section 6.04(c)) shall not exceed $250,000 at any time
outstanding (in each case determined without regard to any write-downs or write-offs); 

  
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 (e)    loans or advances made by a Loan Party to its employees on an
arms-length basis in the ordinary course of business consistent with past practices for travel and entertainment expenses, relocation costs and similar purposes up to a maximum of $250,000 in the aggregate at any one time outstanding; 

(f)    notes payable, or stock or other securities issued by Account Debtors to a Loan Party pursuant to negotiated
agreements with respect to settlement of such Account Debtor’s Accounts in the ordinary course of business, consistent with past practices; and 

(g)    investments received in connection with the disposition of assets permitted by Section 6.05. 

SECTION 6.05.    Asset Sales. No Loan Party will, nor will it permit any Subsidiary to, Dispose of any asset,
including any Equity Interest owned by it, nor will any Borrower permit any Subsidiary to issue any additional Equity Interest in such Subsidiary (other than to another Borrower or another Subsidiary in compliance with Section 6.04), except:

 (a)    Dispositions of (i) Inventory in the ordinary course of business and (ii) used, obsolete, worn out
or surplus Equipment or property in the ordinary course of business; 
 (b)    Dispositions of assets from one Loan
Party to another Loan Party, 
 (c)    Dispositions of Accounts (excluding sales or dispositions in a factoring
arrangement) in connection with the compromise, settlement or collection thereof; 
 (d)    Dispositions of Permitted
Investments; 
 (e)    Permitted Licenses or sublicenses of intellectual property granted in the ordinary course of a
Borrower’s business; 
 (f)    Dispositions resulting from any casualty or other insured damage to, or any taking
under power of eminent domain or by condemnation or similar proceeding of, any property or asset of any Borrower or any Subsidiary; and 

(g)    Dispositions of assets (other than Equity Interests in a Subsidiary unless all Equity Interests in such Subsidiary
are sold) that are not permitted by any other clause of this Section, provided that the aggregate fair market value of all assets Disposed of in reliance upon this paragraph (f) shall not exceed $250,000 during any fiscal year of any Borrower;

 provided that all leases and Dispositions permitted under this Section 6.05 shall be made for fair value and for at least 75% cash
consideration. 
 SECTION 6.06.    Certain Payments of Indebtedness. 

(a)    No Loan Party will, nor will it permit any Subsidiary to, declare or make, or agree to declare or make, directly or
indirectly, any Restricted Payment, or incur any obligation (contingent or otherwise) to do so, except (i) each Borrower may declare and pay dividends with respect to its common stock payable solely in additional shares of its common stock,
and, with respect to its preferred stock, payable solely in additional shares of such preferred stock or in shares of its common stock, and (ii) Subsidiaries may declare and pay dividends ratably with respect to their Equity Interests. 

(b)    No Loan Party will, nor will it permit any Subsidiary to, make or agree to pay or make, directly or indirectly, any
payment or other distribution (whether in cash, securities or other property) of or in respect of principal of or interest on any Indebtedness, or any payment or other distribution (whether in cash, securities or other property), including any
sinking fund or similar deposit, on account of the purchase, redemption, retirement, acquisition, cancellation or termination of any Indebtedness, except (i) payment of Indebtedness created under the Loan Documents, (ii) payment of
regularly scheduled interest and principal payments as and when due in respect of any Indebtedness permitted under Section 6.01, other than payments in respect of the Subordinated Indebtedness prohibited by the subordination provisions thereof,
and (iii) redemption by Borrower of its Equity Interests in an amount not to exceed $100,000 in any fiscal year. 
 SECTION
6.07.    Transactions with Affiliates. No Loan Party will, nor will it permit any Subsidiary to, sell, lease or otherwise transfer any property or assets to, or purchase, lease or otherwise acquire any property or assets
from, or otherwise engage in any other transactions with, any of its Affiliates, except (i) transactions between Loan Parties on fair and reasonable terms in the ordinary course of business and (ii) issuance of Equity Interests that do not
cause or result in a Change in Control. 
 SECTION 6.08.    Restrictive Agreements. No Loan Party will, nor will
it permit any Subsidiary to, directly or indirectly enter into, incur or permit to exist any agreement or other arrangement that prohibits, restricts or imposes any condition upon (a) the ability of such Loan Party or any Subsidiary to create,
incur or permit to exist any Lien upon any of its property or assets, or (b) the ability of any Subsidiary to pay dividends or other distributions with respect to any Equity Interests or to make or repay loans or advances to any Borrower or any
other Subsidiary or to Guarantee Indebtedness of Borrowers or any other Subsidiary. 

  
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 SECTION 6.09.    Amendment of Material Documents. No Loan Party
will, nor will it permit any Subsidiary to, amend, modify or waive any of its material rights under (a) any agreement relating to any Subordinated Indebtedness, (b) its charter, articles or certificate of organization or incorporation and
bylaws or operating, management or partnership agreement, or other organizational or governing documents. 
 SECTION
6.10.    Financial Covenants. Borrowers shall maintain, at all times, the Remaining Months Liquidity. 
 ARTICLE
VII 
 Events of Default 

SECTION 7.01.    Events of Default. If any of the following events (“Events of Default”) shall
occur: 
 (a)    Borrowers shall fail to pay any principal or interest on the Term Loan when and as the same shall
become due and payable, whether at the due date thereof or at a date fixed for prepayment thereof or otherwise; 

(b)    Borrowers shall fail to pay any fee or any other amount (other than an amount referred to in clause (a) of
this Article) payable under this Agreement or any other Loan Document, within three (3) Business Days after the same shall become due and payable; 

(c)    any representation or warranty made or deemed made by or on behalf of any Loan Party or any Subsidiary in or in
connection with this Agreement or any other Loan Document or any amendment or modification hereof or thereof or waiver hereunder or thereunder, or in any report, certificate, financial statement or other document furnished pursuant to or in
connection with this Agreement or any other Loan Document or any amendment or modification hereof or thereof or waiver hereunder or thereunder, shall prove to have been materially incorrect when made or deemed made; 

(d)    any Borrower shall fail to observe or perform any covenant, condition or agreement contained in Article V or in
Article VI; provided, however, notwithstanding the foregoing, Borrowers shall have ten (10) days to cure any default occurring under Sections 5.05, 5.10, and 5.12; 

(e)    any Borrower shall fail to observe or perform any covenant, condition or agreement contained in this Agreement
(other than those specified in clause (a), (b) or (d)), and such failure shall continue unremedied for a period of ten (10) days; 

(f)    any Borrower or any Subsidiary shall fail to make any payment (whether of principal or interest and regardless
of amount) in respect of any Material Indebtedness, when and as the same shall become due and payable; 
 (g)    any
event or condition occurs that results in any Material Indebtedness becoming due prior to its scheduled maturity or that enables or permits (with or without the giving of notice, the lapse of time or both) the holder or holders of any Material
Indebtedness or any trustee or agent on its or their behalf to cause any Material Indebtedness to become due, or to require the prepayment, repurchase, redemption or defeasance thereof, prior to its scheduled maturity; 

(h)    an involuntary proceeding shall be commenced or an involuntary petition shall be filed seeking
(i) liquidation, reorganization or other relief in respect of a Loan Party or any Subsidiary or its debts, or of a substantial part of its assets, under any federal, state or foreign bankruptcy, insolvency, receivership or similar law now or
hereafter in effect or (ii) the appointment of a receiver, trustee, custodian, sequestrator, conservator or similar official for any Loan Party or any Subsidiary or for a substantial part of its assets, and, in any such case, such proceeding or
petition shall continue undismissed for sixty (60) days or an order or decree approving or ordering any of the foregoing shall be entered; 

(i)    any Loan Party or any Subsidiary shall (i) voluntarily commence any proceeding or file any petition seeking
liquidation, reorganization or other relief under any federal, state or foreign bankruptcy, insolvency, receivership or similar law now or hereafter in effect, (ii) consent to the institution of, or fail to contest in a timely and appropriate
manner, any proceeding or petition described in clause (h) of this Article, (iii) apply for or consent to the appointment of a receiver, trustee, custodian, sequestrator, conservator or similar official for such Loan Party or Subsidiary of
any Loan Party or for a substantial part of its assets, (iv) file an answer admitting the material allegations of a petition filed against it in any such proceeding, (v) make a general assignment for the benefit of creditors or
(vi) take any action for the purpose of effecting any of the foregoing; 
 (j)    any Loan Party or any Subsidiary
shall become unable, admit in writing its inability, or publicly declare its intention not to, or fail generally, to pay its debts as they become due; 

  
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 (k)    one or more judgments for the payment of money in an aggregate
amount in excess of $250,000 shall be rendered against any Loan Party, any Subsidiary or any combination thereof and the same shall remain undischarged for a period of thirty (30) consecutive days during which execution shall not be effectively
stayed, or any action shall be legally taken by a judgment creditor to attach or levy upon any assets of any Loan Party or any Subsidiary to enforce any such judgment or any Loan Party or any Subsidiary shall fail within thirty (30) days to
discharge one or more non-monetary judgments or orders which, individually or in the aggregate, could reasonably be expected to have a Material Adverse Effect, which judgments or orders, in any such case, are
not stayed on appeal or otherwise being appropriately contested in good faith by proper proceedings diligently pursued; 

(l)    a Change in Control shall occur; 

(m)    the occurrence of any “default”, as defined in any Loan Document (other than this Agreement), or the
breach of any of the terms or provisions of any Loan Document (other than this Agreement), which default or breach continues beyond any period of grace therein provided; 

(n)    except as permitted by the terms of any Collateral Document, (i) any Collateral Document shall for any reason
fail to create a valid security interest in any Collateral purported to be covered thereby, or (ii) any Lien securing any Secured Obligation shall cease to be a perfected, first priority Lien; 

(o)    any Collateral Document shall fail to remain in full force or effect or any action shall be taken to discontinue or
to assert the invalidity or unenforceability of any Collateral Document; or 
 (p)    any material provision of any Loan
Document for any reason ceases to be valid, binding and enforceable in accordance with its terms (or any Loan Party shall challenge the enforceability of any Loan Document or shall assert in writing, or engage in any action or inaction that
evidences its assertion, that any provision of any of the Loan Documents has ceased to be or otherwise is not valid, binding and enforceable in accordance with its terms). 

then, and in every such event, and at any time thereafter during the continuance of such event, Lender may, by notice to Borrower
Representative, take either or both of the following actions, at the same or different times, to the extent not prohibited by applicable law: (i) terminate the Term Loan Commitment, whereupon the Term Loan Commitment shall terminate
immediately, (ii) declare the Loans then outstanding to be due and payable in whole (or in part, but ratably as among the Term Loan at the time outstanding, in which case any principal not so declared to be due and payable may thereafter be
declared to be due and payable), whereupon the principal of the Loans so declared to be due and payable, together with accrued interest thereon and all fees (including, for the avoidance of doubt, any Prepayment Fees) and other obligations of
Borrowers accrued hereunder and under any other Loan Document, shall become due and payable immediately, in each case without presentment, demand, protest or other notice of any kind, all of which are hereby waived by Borrowers, and
(iii) require cash collateral for the Letters of Credit, if any, in an amount equal to 105% of the Letters of Credit; and in the case of any event with respect to Borrowers described in clause (h) or (i) of this Article, the Term Loan
Commitment shall automatically terminate and the principal of the Loans then outstanding, and cash collateral for the Letters of Credit, together with accrued interest thereon and all fees (including, for the avoidance of doubt, any Prepayment Fees)
and other obligations of Borrowers accrued hereunder and under any other Loan Documents, shall automatically become due and payable, in each case without presentment, demand, protest or other notice of any kind, all of which are hereby waived by
Borrowers. The parties hereto acknowledge and agree that any Prepayment Fee referred to in this Article VII (i) is additional consideration for providing the Term Loan, (ii) constitutes reasonable liquidated damages to compensate Lender
for (and is a proportionate quantification of) the actual loss of the anticipated stream of interest payments upon an acceleration of the Term Loan (such damages being otherwise impossible to ascertain or even estimate for various reasons,
including, without limitation, because such damages would depend on, among other things, (x) when the Term Loan might otherwise be repaid and (y) future changes in interest rates which are not readily ascertainable on the Effective Date),
and (iii) is not a penalty to punish Borrowers for their early prepayment of the Term Loan or the occurrence of any other Prepayment Fee Event, as the case may be. Upon the occurrence and during the continuance of an Event of Default, Lender
may increase the rate of interest applicable to the Loans and other Obligations as set forth in this Agreement and exercise any rights and remedies provided to Lender under the Loan Documents or at law or equity, including all remedies provided
under the UCC. 
 ARTICLE VIII 

Miscellaneous 
 SECTION
8.01.    Notices. 
 (a)    Except in the case of notices and other communications expressly
permitted to be given by telephone (and subject to paragraph (b) below), all notices and other communications provided for herein shall be in writing and shall be delivered by hand or overnight courier service, mailed by certified or registered
mail or sent by fax, as follows: 
  

	 	(i)	 if to any Loan Party, to it in care of Borrower Representative at: 



KALEIDO BIOSCIENCES, INC., on behalf of all Borrowers 

65 Hayden Avenue 

Lexington, MA 02421 

Attention: Alison Lawton, President and CEO 

  
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 With a copy to: 

Goodwin Procter LLP 

100 Northern Avenue 

Boston, MA 02210 

Attention: Mark D. Smith 

Email: marksmith@goodwinlaw.com 
  

	 	(ii)	 if to JPMorgan Chase Bank, N.A. at: 



JPMorgan Chase Bank, N.A. 

Middle Market Servicing 

10 South Dearborn, Floor L2 

Suite IL1-0480 

Chicago, IL, 60603-2300 

Email: jpm.agency.servicing1@jpmorgan.com 

With a copy to: 

JPMorgan Chase Bank, N.A. 

4 New York Plaza 

New York, NY 10004 

Attention: Erica Cross, Vice President 

Email: erica.c.cross@jpmorgan.com 

All such notices and other communications (i) sent by hand or overnight courier service, or mailed by certified or registered mail, shall
be deemed to have been given when received, (ii) sent by fax shall be deemed to have been given when sent, provided that if not given during normal business hours for the recipient, such notice or communication shall be deemed to have
been given at the opening of business on the next Business Day of the recipient, or (iii) delivered through Electronic Systems to the extent provided in paragraph (b) below shall be effective as provided in such paragraph. 

(b)    Notices and other communications to Lender hereunder may be delivered or furnished by using Electronic Systems
pursuant to procedures approved by Lender; provided that the foregoing shall not apply to notices pursuant to Article II or to compliance and no Default certificates delivered pursuant to Sections 5.01(c) and 5.01(d) unless otherwise stated
or agreed by Lender. Lender and each Borrower (on behalf of the Loan Parties) may, in their discretion, agree to accept notices and other communications to it hereunder by using Electronic Systems pursuant to procedures approved by it;
provided that approval of such procedures may be limited to particular notices or communications. All such notices and other communications (i) sent to an e-mail address shall be deemed received
upon the sender’s receipt of an acknowledgement from the intended recipient (such as by the “return receipt requested” function, as available, return e-mail or other written acknowledgement),
provided that if not given during the normal business hours of the recipient, such notice or communication shall be deemed to have been given at the opening of business on the next Business Day for the recipient, and (ii) posted to an Internet
or intranet website shall be deemed received upon the deemed receipt by the intended recipient, at its e-mail address as described in the foregoing clause (i), of notification that such notice or
communication is available and identifying the website address therefor; provided that, for both clauses (i) and (ii) above, if such notice, e-mail or other communication is not sent during the normal
business hours of the recipient, such notice or communication shall be deemed to have been sent at the opening of business on the next Business Day of the recipient. 

(c)    Any party hereto may change its address, facsimile number or e-mail address
for notices and other communications hereunder by notice to the other parties hereto. 
 SECTION 8.02.    Waivers;
Amendments. 
 (a)    No failure or delay by Lender in exercising any right or power hereunder or under any other
Loan Document shall operate as a waiver thereof, nor shall any single or partial exercise of any such right or power, or any abandonment or discontinuance of steps to enforce such a right or power, preclude any other or further exercise thereof or
the exercise of any other right or power. The rights and remedies of Lender hereunder and under any other Loan Document are cumulative and are not exclusive of any rights or remedies that they would otherwise have. No waiver of any provision of any
Loan Document or consent to any departure by any Loan Party therefrom shall in any event be effective unless the same shall be permitted by paragraph (b) of this Section, and then such waiver or consent shall be effective only in the specific
instance and for the purpose for which given. Without limiting the generality of the foregoing, the making of a Loan or issuance of a Letter of Credit shall not be construed as a waiver of any Default, regardless of whether Lender may have had
notice or knowledge of such Default at the time. 

  
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 (b)    Neither this Agreement nor any other Loan Document nor any
provision hereof or thereof may be waived, amended or modified except (i) in the case of this Agreement, pursuant to an agreement or agreements in writing entered into by Borrowers and Lender or (ii) in the case of any other Loan Document,
pursuant to an agreement or agreements in writing entered into by Lender and the Loan Party or Loan Parties that are parties thereto. 

SECTION 8.03.    Expenses; Indemnity; Damage Waiver. 

(a)    The Loan Parties, jointly and severally, shall pay all (i) reasonable out-of-pocket expenses incurred by Lender and its Affiliates, including the reasonable fees, charges and disbursements of counsel for Lender (whether outside counsel or the allocated costs of its internal
legal department), in connection with the credit facilities provided for herein, the preparation and administration of the Loan Documents and any amendments, modifications or waivers of the provisions of the Loan Documents (whether or not the
transactions contemplated hereby or thereby shall be consummated), (ii) reasonable out-of-pocket expenses incurred by Lender in connection with the issuance, amendment,
renewal or extension of any Letter of Credit or any demand for payment thereunder and (iii) out-of-pocket expenses incurred by Lender, including the reasonable and
documented fees, charges and disbursements of any counsel for Lender (whether outside counsel or the allocated costs of its internal legal department), in connection with the enforcement, collection or protection of its rights in connection with the
Loan Documents, including its rights under this Section, or in connection with the Loans made or Letters of Credit issued hereunder, including all such out-of-pocket
expenses incurred during any workout, restructuring or negotiations in respect of such Loans or Letters of Credit. Expenses being reimbursed by the Loan Parties under this Section include, without limiting the generality of the foregoing, fees,
costs and expenses incurred in connection with: 
 (A)    appraisals and insurance reviews; 

(B)    field examinations and the preparation of Reports based on the fees charged by a third party
retained by Lender or the internally allocated fees for each Person employed by Lender with respect to each field examination; 

(C)    background checks regarding senior management and/or key investors, as deemed necessary or
appropriate in the sole discretion of Lender; 
 (D)    Intentionally Omitted; 

(E)    sums paid or incurred to take any action required of any Loan Party under the Loan Documents that
such Loan Party fails to pay or take; and 
 (F)    forwarding loan proceeds, collecting checks and other
items of payment, and establishing and maintaining the accounts and lock boxes, and costs and expenses of preserving and protecting the Collateral. 

All of the foregoing fees, costs and expenses may be charged to Borrowers as the Term Loan or to another deposit account, all as described in
Section 2.09(c). 
 (b)    The Loan Parties, jointly and severally, shall indemnify Lender, and each Related Party
of Lender (each such Person being called an “Indemnitee”) against, and hold each Indemnitee harmless from, any and all losses, claims, damages, penalties, incremental taxes, liabilities and related expenses, including the fees,
charges and disbursements of any counsel for any Indemnitee, incurred by or asserted against any Indemnitee arising out of, in connection with, or as a result of (i) the execution or delivery of the Loan Documents or any agreement or instrument
contemplated thereby, the performance by the parties hereto of their respective obligations thereunder or the consummation of the Transactions or any other transactions contemplated hereby, (ii) any Loan or Letter of Credit or the use of the
proceeds therefrom (including any refusal by Lender to honor a demand for payment under a Letter of Credit if the documents presented in connection with such demand do not strictly comply with the terms of such Letter of Credit), (iii) any
actual or alleged presence or Release of Hazardous Materials on or from any property owned or operated by a Loan Party or a Subsidiary in violation of any Environmental Law, or any Environmental Liability related in any way to a Loan Party or
Subsidiary, (iv) the failure of a Loan Party to deliver to Lender the required receipts or other required documentary evidence with respect to a payment made by such Loan Party for Taxes, or (v) any actual or prospective claim, litigation,
investigation, arbitration or proceeding relating to any of the foregoing, whether or not such claim, litigation, investigation, arbitration or proceeding is brought by any Loan Party or their respective equity holders, Affiliates, creditors or any
other third Person and whether based on contract, tort or any other theory and regardless of whether any Indemnitee is a party thereto; provided that such indemnity shall not, as to any Indemnitee, be available to the extent that such losses,
claims, damages, penalties, liabilities or related expenses are determined by a court of competent jurisdiction by final and non-appealable judgment to have resulted from the gross negligence or willful
misconduct of such Indemnitee. This Section 8.03(b) shall not apply with respect to Taxes other than any Taxes that represent losses or damages arising from any non-Tax claim. 

  
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 (c)    To the extent permitted by applicable law, no Loan Party shall
assert, and each Loan Party hereby waives, any claim against any Indemnitee, (i) for any damages arising from the use by others of information or other materials obtained through telecommunications, electronic or other information transmission
systems (including the Internet), or (ii) on any theory of liability, for special, indirect, consequential or punitive damages (as opposed to direct or actual damages) arising out of, in connection with, or as a result of, this Agreement, any
other Loan Document, or any agreement or instrument contemplated hereby or thereby, the Transactions, the Term Loan, or Letter of Credit or the use of the proceeds thereof; provided that, nothing in this paragraph (c) shall relieve any
Loan Party of any obligation it may have to indemnify an Indemnitee against special, indirect, consequential or punitive damages asserted against such Indemnitee by a third party. 

(d)    All amounts due under this Section shall be payable promptly after written demand therefor. 

SECTION 8.04.    Successors and Assigns. 

(a)    The provisions of this Agreement shall be binding upon and inure to the benefit of the parties hereto and their
respective successors and assigns permitted hereby (including any Affiliate of Lender that issues any Letter of Credit), except that Borrowers may not assign or otherwise transfer any of their rights or obligations hereunder without the prior
written consent of Lender (and any attempted assignment or transfer by Borrowers without such consent shall be null and void). Nothing in this Agreement, expressed or implied, shall be construed to confer upon any Person (other than the parties
hereto, their respective successors and assigns permitted hereby (including any Affiliate of Lender that issues any Letter of Credit), Participants (to the extent provided in paragraph (c) of this Section) and, to the extent expressly
contemplated hereby, the Related Parties of Lender) any legal or equitable right, remedy or claim under or by reason of this Agreement. 

(b)     Lender may assign to one or more assignees all or a portion of its rights and obligations under this Agreement
(including all or a portion of the Term Loan at the time owing to it) to one or more purchasers whether or not related to the Lender. 

(c)    Lender may, without the consent of, or notice to, Borrower Representative, sell participations to one or more banks
or other entities (a “Participant”) in all or a portion of Lender’s rights and/or obligations under this Agreement (including all or a portion of its Term Loan Commitment and/or Letters of Credit and/or the Loans owing to it);
provided that (i) Lender’s obligations under this Agreement shall remain unchanged; (ii) Lender shall remain solely responsible to the other parties hereto for the performance of such obligations; and (iii) Borrowers shall
continue to deal solely and directly with Lender in connection with Lender’s rights and obligations under this Agreement. Borrowers agree that each Participant shall be entitled to the benefits of Article 2 (subject to the requirements and
limitations therein) to the same extent as if they were Lender and had acquired their interest by assignment pursuant to paragraph (b) of this Section; provided that such Participant shall not be entitled to receive any greater payment
under Article 2, with respect to any participation, than its participating Lender would have been entitled to receive, except to the extent such entitlement to receive a greater payment results from a Change in Law that occurs after the Participant
acquired the applicable participation. 
 To the extent permitted by law, each Participant also shall be entitled to the benefits of Section 8.08 as
though it were Lender. If Lender shall sell a participation, it shall, acting solely for this purpose as a non-fiduciary agent of Borrowers, maintain a register on which it enters the name and address of each
Participant and the principal amounts (and stated interest) of each Participant’s interest in the Loans or other obligations under this Agreement or any other Loan Document (the “Participant Register”); provided that
Lender shall have no obligation to disclose all or any portion of the Participant Register (including the identity of any Participant or any information relating to a Participant’s interest in the Term Loan, Letters of Credit or its other
obligations under this Agreement or any other Loan Document) to any Person except to the extent that such disclosure is necessary to establish that the Term Loan, Letter of Credit, or other obligation is in registered form under Section 5f.103-1(c) of the U.S. Treasury Regulations. The entries in the Participant Register shall be conclusive absent manifest error, and Lender shall treat each Person whose name is recorded in the
Participant Register as the owner of such participation for all purposes of this Agreement notwithstanding any notice to the contrary. 

(d)    Lender may at any time pledge or assign a security interest in all or any portion of its rights under this
Agreement to secure obligations of Lender, including without limitation any pledge or assignment to secure obligations to a Federal Reserve Bank, and this Section shall not apply to any such pledge or assignment of a security interest;
provided that no such pledge or assignment of a security interest shall release Lender from any of its obligations hereunder or substitute any such pledgee or assignee for Lender as a party hereto. 

SECTION 8.05.    Survival. All covenants, agreements, representations and warranties made by the Loan Parties in
the Loan Documents and in the certificates or other instruments delivered in connection with or pursuant to this Agreement or any other Loan Document shall be considered to have been relied upon by the other parties hereto and shall survive the
execution and delivery of the Loan Documents and the making of any Loans and issuance of any Letters of Credit, regardless of any investigation made by any such other party or on its behalf and notwithstanding that Lender may have had notice or
knowledge of any Default or incorrect representation or warranty at the time any credit is extended hereunder, and shall continue in full force and effect as long as the principal of or any accrued interest on any Loan or any fee or any other amount
payable under this Agreement is 

  
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outstanding and unpaid or any Letter of Credit is outstanding and so long as the Term Loan Commitment has not expired or terminated. The provisions of Section 8.03 shall survive and remain
in full force and effect regardless of the consummation of the transactions contemplated hereby, the repayment of the Loans, the expiration or termination of the Letters of Credit and the Term Loan Commitment or the termination of this Agreement or
any other Loan Document or any provision hereof or thereof. 
 SECTION 8.06.    Counterparts; Integration;
Effectiveness; Electronic Execution. 
 (a)    This Agreement may be executed in counterparts (and by different
parties hereto on different counterparts), each of which shall constitute an original, but all of which when taken together shall constitute a single contract. This Agreement, the other Loan Documents and any separate letter agreements with respect
to fees payable to Lender constitute the entire contract among the parties relating to the subject matter hereof and supersede any and all previous agreements and understandings, oral or written, relating to the subject matter hereof. Except as
provided in Section 4.01, this Agreement shall become effective when it shall have been executed by Lender and when Lender shall have received counterparts hereof which, when taken together, bear the signatures of each of the other parties
hereto, and thereafter shall be binding upon and inure to the benefit of the parties hereto and their respective successors and assigns. 

(b)    Delivery of an executed counterpart of a signature page of this Agreement by fax, emailed pdf. or any other
electronic means that reproduces an image of the actual executed signature page shall be effective as delivery of a manually executed counterpart of this Agreement. The words “execution,” “signed,” “signature,”
“delivery,” and words of like import in or relating to any document to be signed in connection with this Agreement and the transactions contemplated hereby or thereby shall be deemed to include Electronic Signatures, deliveries or the
keeping of records in electronic form, each of which shall be of the same legal effect, validity or enforceability as a manually executed signature, physical delivery thereof or the use of a paper-based recordkeeping system, as the case may be, to
the extent and as provided for in any applicable law, including the Federal Electronic Signatures in Global and National Commerce Act, the New York State Electronic Signatures and Records Act, or any other similar state laws based on the Uniform
Electronic Transactions Act. 
 SECTION 8.07.    Severability. Any provision of any Loan Document held to be
invalid, illegal or unenforceable in any jurisdiction shall, as to such jurisdiction, be ineffective to the extent of such invalidity, illegality or unenforceability without affecting the validity, legality and enforceability of the remaining
provisions thereof; and the invalidity of a particular provision in a particular jurisdiction shall not invalidate such provision in any other jurisdiction. 

SECTION 8.08.    Right of Setoff. If an Event of Default shall have occurred and be continuing, Lender and each of
its Affiliates is hereby authorized at any time and from time to time, to the fullest extent permitted by law, to set off and apply any and all deposits (general or special, time or demand, provisional or final) at any time held and other
obligations at any time owing by Lender or any Affiliate to or for the credit or the account of any Loan Party against any and all of the Secured Obligations then due, irrespective of whether or not Lender shall have made any demand under this
Agreement or any other Loan Document and although such obligations of the Loan Parties may be owed to a branch office or Affiliate of Lender different from the branch office or Affiliate holding such deposit or obligated on such indebtedness. The
rights of Lender under this Section are in addition to other rights and remedies (including other rights of setoff) which Lender may have. 

SECTION 8.09.    Governing Law; Jurisdiction; Consent to Service of Process. 

(a)    The Loan Documents (other than those containing a contrary express choice of law provision) shall be governed by and
construed in accordance with the internal laws of the State of New York, but giving effect to federal laws applicable to national banks. 

(b)    Each of the parties hereto hereby irrevocably and unconditionally submits, for itself and its property, to the
nonexclusive jurisdiction of any U.S. federal or New York State court sitting in New York, New York, and any appellate court from any thereof, in any action or proceeding arising out of or relating to any Loan Documents, the transactions relating
hereto or thereto, or for recognition or enforcement of any judgment, and each of the parties hereto hereby irrevocably and unconditionally agrees that all claims in respect of any such action or proceeding may (and any such claims, cross-claims or
third party claims brought against Lender or any of its Related Parties may only) be heard and determined in such state court or, to the extent permitted by law, in such federal court. Each of the parties hereto agrees that a final judgment in any
such action or proceeding shall be conclusive and may be enforced in other jurisdictions by suit on the judgment or in any other manner provided by law. Nothing in this Agreement or any other Loan Document shall affect any right that Lender may
otherwise have to bring any action or proceeding relating to this Agreement or any other Loan Document against any Loan Party or its properties in the courts of any jurisdiction. 

(c)    Each Loan Party hereby irrevocably and unconditionally waives, to the fullest extent it may legally and effectively
do so, any objection which it may now or hereafter have to the laying of venue of any suit, action or proceeding arising out of or relating to this Agreement or any other Loan Document in any court referred to in paragraph (b) of this Section.
Each of the parties hereto hereby irrevocably waives, to the fullest extent permitted by law, the defense of an inconvenient forum to the maintenance of such action or proceeding in any such court. 

  
 27 













 (d)    Each party to this Agreement irrevocably consents to service of
process in the manner provided for notices in Section 8.01. Nothing in this Agreement or any other Loan Document will affect the right of any party to this Agreement to serve process in any other manner permitted by law. 

SECTION 8.10.    WAIVER OF JURY TRIAL. EACH PARTY HERETO HEREBY WAIVES, TO THE FULLEST EXTENT PERMITTED BY
APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN ANY LEGAL PROCEEDING DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS AGREEMENT, ANY OTHER LOAN DOCUMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY (WHETHER BASED ON
CONTRACT, TORT OR ANY OTHER THEORY). EACH PARTY HERETO (A) CERTIFIES THAT NO REPRESENTATIVE OR OTHER AGENT (INCLUDING ANY ATTORNEY) OF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF
LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER AND (B) ACKNOWLEDGES THAT IT AND THE OTHER PARTIES HERETO HAVE BEEN INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION. 

SECTION 8.11.    Headings. Article and Section headings and the Table of Contents used herein are for convenience
of reference only, are not part of this Agreement and shall not affect the construction of, or be taken into consideration in interpreting, this Agreement. 

SECTION 8.12.    Confidentiality. Lender agrees to maintain the confidentiality of the Information (as defined
below), except that Information may be disclosed (a) to its and its Affiliates’ directors, officers, employees and agents, including accountants, legal counsel and other advisors (it being understood that the Persons to whom such
disclosure is made will be informed of the confidential nature of such Information and instructed to keep such Information confidential), (b) to the extent requested by any Governmental Authority (including any self-regulatory authority, such
as the National Association of Insurance Commissioners), (c) to the extent required by any Requirement of Law or by any subpoena or similar legal process, (d) to any other party to this Agreement, (e) in connection with the exercise
of any remedies hereunder or under any other Loan Document or any suit, action or proceeding relating to this Agreement or any other Loan Document or the enforcement of rights hereunder or thereunder, (f) subject to an agreement containing
provisions substantially the same as those of this Section, to (x) any assignee of or Participant in, or any prospective assignee of or Participant in, any of its rights or obligations under this Agreement or (y) any actual or prospective
counterparty (or its advisors) to any swap or derivative transaction relating to the Loan Parties and their obligations, (g) with the consent of Borrower Representative, (h) to holders of Equity Interests in any Borrower, (i) to any
Person providing a Guarantee of all or any portion of the Secured Obligations. For the purposes of this Section, “Information” means all information received from Borrowers relating to Borrowers or their businesses, other than any
such information that is available to Lender on a non-confidential basis prior to disclosure by Borrowers; provided that, in the case of information received from Borrowers after the date hereof, such
information is clearly identified at the time of delivery as confidential. Any Person required to maintain the confidentiality of Information as provided in this Section shall be considered to have complied with its obligation to do so if such
Person has exercised the same degree of care to maintain the confidentiality of such Information as such Person would accord to its own confidential information. 

SECTION 8.13.    Violation of Law. Anything contained in this Agreement to the contrary notwithstanding, Lender
shall not be obligated to extend credit to Borrowers in violation of any Requirement of Law. 
 SECTION 8.14.    USA
PATRIOT Act. Lender is subject to the requirements of the USA PATRIOT Act and hereby notifies each Loan Party that pursuant to the requirements of the USA PATRIOT Act, it is required to obtain, verify and record information that identifies such
Loan Party, which information includes the name and address of such Loan Party and other information that will allow Lender to identify such Loan Party in accordance with the USA PATRIOT Act. 

SECTION 8.15.    Disclosure. Each Loan Party hereby acknowledges and agrees that Lender and/or its Affiliates from
time to time may hold investments in, make other loans to or have other relationships with, any of the Loan Parties and their respective Affiliates. 

SECTION 8.16.    Interest Rate Limitation. Notwithstanding anything herein to the contrary, if at any time the
interest rate applicable to any Loan, together with all fees, charges and other amounts which are treated as interest on such Loan under applicable law (collectively the “Charges”), shall exceed the maximum lawful rate (the
“Maximum Rate”) which may be contracted for, charged, taken, received or reserved by Lender holding such Loan in accordance with applicable law, the rate of interest payable in respect of such Loan hereunder, together with all
Charges payable in respect thereof, shall be limited to the Maximum Rate and, to the extent lawful, the interest and Charges that would have been payable in respect of such Loan but were not payable as a result of the operation of this Section shall
be cumulated and the interest and Charges payable to Lender in respect of other Loans or periods shall be increased (but not above the Maximum Rate therefor) until such cumulated amount, together with interest thereon at the NYFRB Rate to the date
of repayment, shall have been received by Lender. 
 SECTION 8.17.    No Fiduciary Duty, etc. (a) Each
Borrower acknowledges and agrees, and acknowledges its Subsidiaries’ understanding, that Lender will not have any obligations except those obligations expressly set forth herein and in 

  
 28 













 
the other Loan Documents and Lender is acting solely in the capacity of an arm’s length contractual counterparty to Borrowers with respect to the Loan Documents and the transactions
contemplated herein and therein and not as a financial advisor or a fiduciary to, or an agent of, Borrowers or any other person. Each Borrower agrees that they will not assert any claim against Lender based on an alleged breach of fiduciary duty by
Lender in connection with this Agreement and the transactions contemplated hereby. Additionally, Borrowers acknowledge and agree that Lender is not advising Borrowers as to any legal, tax, investment, accounting, regulatory or any other matters in
any jurisdiction. Borrowers shall consult with their own advisors concerning such matters and shall be responsible for making their own independent investigation and appraisal of the transactions contemplated herein or in the other Loan Documents,
and Lender shall have no responsibility or liability to Borrowers with respect thereto. 
 (b)    Each Borrower further
acknowledges and agrees, and acknowledges its Subsidiaries’ understanding, that Lender, together with its Affiliates, is a full service securities or banking firm engaged in securities trading and brokerage activities as well as providing
investment banking and other financial services. In the ordinary course of business, Lender may provide investment banking and other financial services to, and/or acquire, hold or sell, for its own accounts and the accounts of customers, equity,
debt and other securities and financial instruments (including bank loans and other obligations) of, Borrowers and other companies with which Borrowers may have commercial or other relationships. With respect to any securities and/or financial
instruments so held by Lender or any of its customers, all rights in respect of such securities and financial instruments, including any voting rights, will be exercised by the holder of the rights, in its sole discretion. 

(c)    In addition, each Borrower acknowledges and agrees, and acknowledges their Subsidiaries’ understanding, that
Lender and its Affiliates may be providing debt financing, equity capital or other services (including financial advisory services) to other companies in respect of which Borrowers may have conflicting interests regarding the transactions described
herein and otherwise. Lender will not use confidential information obtained from Borrowers by virtue of the transactions contemplated by the Loan Documents or its other relationships with Borrowers in connection with the performance by Lender of
services for other companies, and Lender will not furnish any such information to other companies. Borrowers also acknowledge that Lender has no obligation to use in connection with the transactions contemplated by the Loan Documents, or to furnish
to Borrowers, confidential information obtained from other companies. 
 SECTION 8.18.    Marketing Consent. Upon
prior written approval by Borrowers, in each case, and at their sole expense, Lender may publish such tombstones and give such other publicity to this Agreement as it may from time to time determine in its sole discretion. The foregoing
authorization shall remain in effect unless Borrowers notifies Lender in writing that such authorization is revoked. 
 ARTICLE IX 

The Borrower Representative. 

SECTION 9.01.    Appointment; Nature of Relationship. Each Responsible Officer hereby is appointed by each of the
Borrowers as its contractual representative (together, the “Borrower Representative”) hereunder and under each other Loan Document, and each of the Borrowers irrevocably authorizes the Borrower Representative to act as the
contractual representative of such Borrower with the rights and duties expressly set forth herein and in the other Loan Documents. The Borrower Representative agrees to act as such contractual representative upon the express conditions contained in
this Article X. Additionally, the Borrowers hereby appoint the Borrower Representative as their agent to receive all of the proceeds of the Loans in the Funding Account(s), at which time the Borrower Representative shall promptly disburse such Loans
to the appropriate Borrower(s). Lender, and its respective officers, directors, agents or employees, shall not be liable to the Borrower Representative or any Borrower for any action taken or omitted to be taken by the Borrower Representative or the
Borrowers pursuant to this Section 9.01. 
 SECTION 9.02.    Powers. The Borrower Representative shall have
and may exercise such powers under the Loan Documents as are specifically delegated to the Borrower Representative by the terms of each thereof, together with such powers as are reasonably incidental thereto. The Borrower Representative shall have
no implied duties to the Borrowers, or any obligation to Lender to take any action thereunder except any action specifically provided by the Loan Documents to be taken by the Borrower Representative. 

SECTION 9.03.    Employment of Agents. The Borrower Representative may execute any of its duties as the Borrower
Representative hereunder and under any other Loan Document by or through authorized officers. 
 SECTION
9.04.    Notices. Each Borrower shall immediately notify the Borrower Representative of the occurrence of any Default or Event of Default hereunder, refer to this Agreement, describe such Default or Event of Default, and
state that such notice is a “notice of default”. In the event that the Borrower Representative receives such a notice, the Borrower Representative shall give prompt notice thereof to Lender. Any notice provided to the Borrower
Representative hereunder shall constitute notice to each Borrower on the date received by the Borrower Representative. 

  
 29 













 SECTION 9.05.    Successor Borrower Representative. Upon the
prior written consent of Lender, the Borrower Representative may resign at any time, such resignation to be effective upon the appointment of a successor Borrower Representative. 

SECTION 9.06.    Execution of Loan Documents. The Borrowers hereby empower and authorize the Borrower
Representative, on behalf of the Borrowers, to execute and deliver to the Lender the Loan Documents and all related agreements, certificates, documents, or instruments as shall be necessary or appropriate to effect the purposes of the Loan
Documents, including, without limitation, the Compliance Certificates. Each Borrower agrees that any action taken by the Borrower Representative or the Borrowers in accordance with the terms of this Agreement or the other Loan Documents, and the
exercise by the Borrower Representative of its powers set forth therein or herein, together with such other powers that are reasonably incidental thereto, shall be binding upon all of the Borrowers. 

SECTION 9.07.    Reporting. Each Borrower hereby agrees that such Borrower shall furnish promptly after each fiscal
month to the Borrower Representative a copy of the Compliance Certificate or any other certificate or report required hereunder or requested by the Borrower Representative on which the Borrower Representative shall rely to prepare the Compliance
Certificate required pursuant to the provisions of this Agreement. 
 [Balance of Page Intentionally Left Blank]


  
 30 













 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed by
their respective authorized officers as of the day and year first above written. 
  

			
	KALEIDO BIOSCIENCES, INC.
		
	By:	 	 /s/ Alison Lawton

	Name:	 	Alison Lawton
	Title: 	 	President, Chief Executive Officer
	
	CADENA BIO, INC.
		
	By:	 	 /s/ Alison Lawton

	Name:	 	Alison Lawton
	Title:	 	President
	
	JPMORGAN CHASE BANK, N.A..
		
	By:	 	 /s/ Erica Cross

	Name:	 	Erica Cross
	Title:	 	Authorized Officer



  
 [Signature
Page to Credit Agreement] 













 SCHEDULE 3.05 

Properties, etc. 
 Lease Agreement by and
between HCP/King Hayden Campus LLC and the Company, dated March 19, 2018, as amended to date, for premises located at 65 Hayden Avenue, Lexington, MA 02421 

Lease Agreement by and between DIV Bedford, LLC and the Company, dated May 15, 2017, as amended to date, for premises located at 18 Crosby Drive,
Bedford, MA 01730 
 SCHEDULE 3.06 

Disclosed Matters 
 None. 

SCHEDULE 3.12 

Material Agreements 
 Not Applicable. 

SCHEDULE 3.14 

Insurance 
 Delivered to Bank on the
Effective Date. 
 SCHEDULE 3.15 

Capitalization and Subsidiaries 

[***] 












 SCHEDULE 3.19 

Affiliate Transactions 
 Community of
Legal Interest Agreement between Flagship Ventures Management, Inc. and Kaleido Biosciences, Inc. (formerly VL32, Inc.) effective January 27, 2015 

Amended and Restated License Agreement between Cadena Bio Inc. and Midori USA, Inc. dated April 14, 2016 

License Agreement between Cadena Bio Inc. and Midori USA, Inc. effective as of June 16, 2015 (license was assigned from Kaleido Biosciences, Inc. to
Cadena Bio Inc. on April 14, 2016) 
 Second Amended and Restated Investors’ Rights Agreement among Kaleido Biosciences, Inc. and certain of its
stockholders, dated February 21, 2018 
 Side Letter Agreement among Kaleido Biosciences, Inc., Cadena Bio Inc. and Midori USA, Inc. dated
August 14, 2019 
 SCHEDULE 6.01 

Existing Indebtedness 
 Letter of Credit
with Square1 Bank issued in connection with the security deposit requirement under the lease for space at 18 Crosby Drive, Bedford MA in the amount of $117,156.33. 

Letter of Credit with Square1 Bank issued in connection with the security deposit requirement under the lease for space at 65 Hayden Street, Lexington MA in
the amount of $2,057,658.75. 
 Line of Credit with American Express issued in connection with the Company’s corporate credit card program in the
amount of $1,000,000.00. 
 SCHEDULE 6.02 

Existing Liens 
 Lien of De Lage Lander
Financial Services on a leased asset of Kaleido Biosciences, Inc. 
 SCHEDULE 6.04 

Existing Investments 
  

																	
	 Entity/Subsidiary
	  	 Type
	  	Number of Shares	 	  	Class of Stock	 	  	Ownership %	 	 	 Notes

	 Cadena Bio, Inc.
	  	C-Corporation (DE)	  	 	1,000	 	  	 	Common	 	  	 	100	% 	 	Owned by Kaleido Biosciences, Inc.
	 Kaleido Biosciences Securities Corporation
	  	MA Securities Corporation	  	 	1,000	 	  	 	Common	 	  	 	100	% 	 	Owned by Kaleido Biosciences, Inc.

 SCHEDULE 6.08 

Existing Restrictions 
 None. 












 EXHIBIT A 

COMPLIANCE CERTIFICATE 
  

	To:	 JPMorgan Chase Bank, N.A. 



This Compliance Certificate (“Certificate”), for the period ended         
    , 201  , is furnished pursuant to that certain Credit Agreement dated as of October 25, 2019 (as amended, restated, modified, renewed or extended from time to time, the “Agreement”), by and among
KALEIDO BIOSCIENCES, INC. and CADENA BIO, INC. (each, a “Borrower” and collectively, “Borrowers”) and JPMORGAN CHASE BANK, N.A., as Lender. Unless otherwise defined herein, capitalized terms used in this
Certificate have the meanings ascribed thereto in the Agreement. 
 THE UNDERSIGNED HEREBY CERTIFIES THAT: 

1.    I am the
                     of Borrowers and I am authorized to deliver this Certificate on behalf of Borrowers and their Subsidiaries; 

2.    I have reviewed the terms of the Agreement and I have made, or have caused to be made under my supervision, a
detailed review of the compliance of Borrowers and their Subsidiaries with the Agreement during the accounting period covered by the attached financial statements (the “Relevant Period”); 

3.    The attached financial statements of Borrowers and, as applicable, its Subsidiaries and/or Affiliates for the
Relevant Period: (a) have been prepared on an accounting basis (the “Accounting Method”) consistent with the requirements of the Agreement and, except as may have been otherwise expressly agreed to in the Agreement, in accordance with
GAAP consistently applied, and (b) to the extent that the attached are not Borrowers’ annual fiscal year end statements, are subject to normal year-end audit adjustments and the absence of footnotes;

 4.     The examinations described in paragraph 2 did not disclose and I have no knowledge of, except as set forth
below, (a) the existence of any condition or event which constitutes a Default or an Event of Default under the Agreement or any other Loan Document during or at the end of the Relevant Period or as of the date of this Certificate or
(b) any change in the Accounting Method or in the application thereof that has occurred since the date of the annual financial statements delivered to Lender in connection with the closing of the Agreement or subsequently delivered as required
in the Agreement; 
 5.    I hereby certify that, except as set forth below, no Loan Party has changed (i) its
name, (ii) its chief executive office, (iii) its principal place of business, (iv) the type of entity it is or (v) its state of incorporation or organization without having given Lender the notice required by Section 4.15 of
the Security Agreement; 
 6. The representations and warranties of the Loan Parties set forth in the Loan Documents are true and correct as
of the date hereof, except to the extent that any such representation or warranty specifically refers to an earlier date, in which case it is true and correct only as of such earlier date; 

7. Schedule I attached hereto sets forth financial data and computations evidencing Borrowers’ compliance with certain covenants
of the Agreement, all of which data and computations are true, complete and correct; and 
 Described below are the exceptions, if any,
referred to in paragraph 4 hereof by listing, in detail, the (i) nature of the condition or event, the period during which it has existed and the action which Borrowers have taken, is taking, or proposes to take with respect to each such
condition or event or (ii) change in the Accounting Method or the application thereof and the effect of such change on the attached financial statements: 

                       
                                         
                                         
                                         
                                         
                                         
         

                       
                                         
                                         
                                         
                                         
                                         
         

                       
                                         
                                         
                                         
                                         
                                         
         
 [Balance of Page Intentionally Left Blank] 












 The foregoing certifications, together with the computations set forth in Schedule I hereto
and the financial statements delivered with this Certificate in support hereof, are made and delivered this      day of         , 20    .

  

			
	KALEIDO BIOSCIENCES, INC.
		
	By:	 	
                     
                    

	Name:	 	  

	Title:	 	  

	
	CADENA BIO, INC.
		
	By:	 	  

	Name:	 	  

	Title:	 	  




  
 [Signature
Page to Compliance Certificate] 













 Schedule I to Compliance Certificate 

Compliance as of             , 20     with 

Provision of 6.10 of the Agreement 
 6.10
Financial Covenant. 
 Required: Remaining Months Liquidity of at least 3. 

Actual:
                                     

                     No, not in
compliance                    
                     Yes, in compliance 












 Schedule I to Compliance Certificate 

Provide a brief summary of the terms of any exclusive license not yet listed on any previous Compliance Certificate and attach copies of the final executed
licensing documents for any such exclusive license.