<TABLE> <S> <C>

<PAGE>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM DRKOOP.COM,
INC.'S QUARTERLY REPORT ON FORM 10-Q FOR THE PERIOD ENDED SEPTEMBER 30, 1999 AND
IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000

<S>                             <C>                     <C>
<PERIOD-TYPE>                   9-MOS                   9-MOS
<FISCAL-YEAR-END>                          DEC-31-1998             DEC-31-1999
<PERIOD-START>                             JAN-01-1998             JAN-01-1999
<PERIOD-END>                               SEP-30-1998             SEP-30-1999
<CASH>                                             345                  49,077
<SECURITIES>                                         0                       0
<RECEIVABLES>                                        0                   2,818
<ALLOWANCES>                                         0                    (100)
<INVENTORY>                                          0                       0
<CURRENT-ASSETS>                                   514                  75,009
<PP&E>                                             271                   6,861
<DEPRECIATION>                                     (40)                   (740)
<TOTAL-ASSETS>                                     756                  96,493
<CURRENT-LIABILITIES>                            1,407                  15,787
<BONDS>                                              0                       0
<PREFERRED-MANDATORY>                                0                       0
<PREFERRED>                                          0                       0
<COMMON>                                            10                      30
<OTHER-SE>                                         641                  80,676
<TOTAL-LIABILITY-AND-EQUITY>                       756                  96,493
<SALES>                                              0                   4,333
<TOTAL-REVENUES>                                     0                       0
<CGS>                                                0                       0
<TOTAL-COSTS>                                      996                  28,643
<OTHER-EXPENSES>                                     0                  12,438
<LOSS-PROVISION>                                 4,489                     100
<INTEREST-EXPENSE>                                  26                     587
<INCOME-PRETAX>                                 (5,460)                (62,663)
<INCOME-TAX>                                         0                       0
<INCOME-CONTINUING>                                  0                       0
<DISCONTINUED>                                       0                       0
<EXTRAORDINARY>                                      0                       0
<CHANGES>                                            0                       0
<NET-INCOME>                                    (5,460)                (62,663)
<EPS-BASIC>                                         (1)                     (4)
<EPS-DILUTED>                                       (1)                     (4)


</TABLE>