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EPA REGISTRATION DIVISION COMPANY NOTICE OF FILING FOR PESTICIDE PETITIONS PUBLISHED IN THE FEDERAL REGISTER EPA Registration Division contact: [PV Shaw (703) 308-1846] 

### INSTR U CTIO N S: Please utilize this outlin e in preparing the pesticide petition
. In cases where the outline element does not appl y, please insert " NA-Remo v e " and maintain the outline. Plea s e do not change the margins , font, or format in y our pesticide petiti o n. Simpl y replace the in structions that appear in green , i. e. , " [insert company name) ," with the information s pecific to your action. 

### TEMPLATE: [Evonik Goldschmidt Corporation] [Insert petition number] EPA has rcce1vcd a pestictde petition (I N A-Remove ]) from [Evonik Corporation] , [PO Box 1299 , Hopewell, VA 23860] proposing, pursuant to section 408(d) ofthe Federal Food, Drug, and Cosmet1c Act (FFDCA), 21 U.S.C. 346a(d), to amend 40 CFR part 180. ( Optio ns (pi ck on e) I. by establishing a tolerance for residues of- N A

- R emo v e 2. to establish an exemption from the requirement of a tolerance for [ Oxirane, 2-phenyl-, polymer with oxirane, monooctyl ether, minimum number average molecular weight (in AMU) 1 , 271 and CAS Reg. No. 83653-00-3 ] under 40 CFR , 0 960 \\hen used a:-. .m 111<.:n mgred1ent (functiomng as 1 dtspersant) in pesticide tonnulations. EPA has detennined that the petition contains data or information regarding the elements set forth in section 408 (d)(2) of FDDCA; however, EPA ha:. not fully C\ aluated the sutlicicncy of the submitted data at this time or whcthi'J the data supports granting of the petition. Additional data may be needed before EPA rules on the petition. A
. Residue Chcmi\'fl'\' I. Plallf metaboli'im
. 2. 

### Anal\ tical merlzo NA-Removc



# 22 3. \1agnitude of re.sidues NA-Remove B. l oxicological Profile l. Acllle toxicitJ NA-Remove 2. Genotoxicty NA-Remove 3. Reproductive and derelopmelllal toxicifl NA-Remove 4. Subchronic uniciz\ NA-Remove 5. Chrome toxicif\ NA-Remove 6
. . 1nimal metabolism. NA-Remove 7. Metabolite toxicolog) NA-Remove 8. Endocrine disrupti01 NA-Remove The d ef"mition o f a polymer is given in 40 CFR 723.250(b) and the exclusion criteria for identifying these low-risk poly mers are described in 40 C FR 723.250(d)
. Oxirane, 2-phenyl-, polymer with oxirane, monooctyl e ther , minimum number av e rage molecular weight (in AMU) 1,271 and C AS Reg. No. 83653-00-3 conforms to th e definition of a pol y mer g iven in 40 CFR 7 23
. 250(b) a nd me ets th e following criteria that a r e us e d to id e ntif y low-risk polymer s . 1. Th e polymer i s not cationic , nor do es it hav e the potential to become cationi c. 2
. The pol y m e r do es contain a s an integ r a l part of its compo s ition th e atomic el e ment s carbon , h ydro gen , a nd oxygen . 3
. Th e poly m er doc s not contain a s an int eg ral part of its composition , ex cept a s impurities , an y el e ment other than tho s e li s ted in 40 C F R 7 2 3.2 50 ( d ) (2)(ii ). 4
. T he p oly m er is n eith er de sign e d nor can it b e r e asonably a nticip a t e d to s u bs tantially degra d e , d ec ompos e, or depoly m erizc
. 5. T h e p olymer is m a nufa c ture d o r imp or ted f r o m mono m e r s a n d/or reactants that a r e a l ready in cluded on t h e TSCA Chemica l Substa n ce I nventory or manufac tu red u n der an app li cab l e TSCA section 5 exe m ption. 6. The po ly m er is not a wat er a b sorbi n g polymer w ith a n umber average molecular weigh t (MW) greater than or equal to 10, 000 daltons. Additionally , the polymer also meets as required t h e following exemption criteria specified in 40 CFR 723.250(e)(l)
. 7
. The polymer's number average MW of 1,271 daltons and contains approximatel) 1 % oligomeric material below M\V 500 and 12 % material below3 MW 1000 , th er efo re sati s fyin g th e number ave rage molecular w e ig ht and oli gomeric c ontent require m ent s p ecifi ed und e r 7 2 3. 2SO (e)(l). Thu s, Oxirane , 2

- ph e n y l- , poly mer with ox irane, mono octyl ether mee ts the c riteri a for a polyme r t o b e considered low risk under 40 CFR 723
. 250. Based on its c onf o rmanc e to the criteria in t his unit , no mammalian t ox ici ty i s a nti c ipated from dieta r y, inh a lati o n , o r derm a l ex posure t o Oxirane, 2

- ph en yl- , poly mer with oxira ne, monooctyl ether
.

For th e purpo ses of assessing potenti a l ex posur e under thi s exe mption , EPA considered th a t O x ir a nc , 2-phenyl- , pol y mer with oxirane, monooctyl ether could be present in all r a w a nd processed agricultur a l commoditie s and drinkin g water , and that non-occupation a l n on - dietary expo s u re wa s po ss ibl e. The numb er ave ra g e MW of Oxira ne , 2-phen y l -, p oly m er with ox ir a n e, monooctyl ether i s 1 ,2 71 d a lto n s . Generally, a poly m e r of thi s size would be poorly ab so rb ed thr o ugh the intact gas troin t e s tin a l tr act or th r ough intact human s kin
. Since Oxiran e, 2-ph en y l- , poly m e r with oxirane , monooc ty l eth e r conform s to the cri te ria th a t id entif y a low-ris k polymer , there are n o c oncerns fo r risks associated wi t h any potential ex posure sc enarios that are r e a s onabl y fores ee able
. l. Die/at)' e.\posure. NA-Remove i. Food NA-Remove ii
. Drinl..ing ware NA-Remove 2. Non -dietliiJ '

**e:~.posure.** NA-Remove 

## n. Cumulati\·e E.f!i.•cts Section 40 8 (b )(2) (D )(v) o f FFD CA r eq uires t h a t, wh en co n s id erin g wh et h er t o es t ab li s h , m o di fy, o r r evok e a to le ranc e , th e Age n cy co n si d er " avail a bl e inform a ti o n " co n ce rnin g t h e c umulati ve ef fec t s of a partic ular p es ticid e's resid u es and " other substances that have a common mec h a ni sm of tox i city." EPA has not found Oxirane , 2-pheny l- , polymer with oxirane, monooctyl ethe
. . to share a common mechanism of toxicity with any oth er substances, and Oxirane , 2-pheny l

- , polymer with oxirane, monoocty l ether does not appear to produce a toxic metabolite produced by other substances
. For the purposes of t;ais tolerance action, therefore , EPA bas assumed that Oxirane , 2-phenyl

- , polymer witt: oxirane, monooctyl ether does not have a common mechanism of toxicity with other substances. E Safety Determination4 S r 1 ' 11 Oxirane , 2-pbenyl- , polymer with oxirane, monooctyl ether, qualifyin g as a low concern polymer, is not expected to pose toxicity risk
. 2. lnfant'i and clllldren. Due to the low toxicity of Oxirane, 2-pben y l-, polymer with oxirane, monooctyl ether, a safety factor anal y sis is not necessary. 

### F. Imernational Tolerances Th e C odex bas not establi s hed a MRL for Oxirane, 2-pben y l- , poly mer with oxirane , monooctyl ether.