<TABLE> <S> <C>

<PAGE>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM DRKOOP.COM,
INC.'S REPORT ON FORM 10-Q FOR THE NINE MONTHS ENDED SEPTEMBER 30, 2000 AND IS
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER>    1,000

<S>                             <C>                     <C>
<PERIOD-TYPE>                   3-MOS                   3-MOS
<FISCAL-YEAR-END>                          DEC-31-2000             DEC-31-1999
<PERIOD-START>                             JAN-01-2000             JAN-01-1999
<PERIOD-END>                               SEP-30-2000             SEP-30-1999
<CASH>                                          17,361                  35,706
<SECURITIES>                                         0                       0
<RECEIVABLES>                                    2,641                   6,611
<ALLOWANCES>                                     (931)                    (79)
<INVENTORY>                                          0                       0
<CURRENT-ASSETS>                                37,135                  69,100
<PP&E>                                          14,985                  11,985
<DEPRECIATION>                                 (5,354)                 (1,550)
<TOTAL-ASSETS>                                  47,156                  99,720
<CURRENT-LIABILITIES>                           11,812                  22,798
<BONDS>                                              0                       0
<PREFERRED-MANDATORY>                                0                       0
<PREFERRED>                                          3                       0
<COMMON>                                            38                      30
<OTHER-SE>                                      30,747                  71,287
<TOTAL-LIABILITY-AND-EQUITY>                    47,156                  99,720
<SALES>                                          2,046                   2,910
<TOTAL-REVENUES>                                 2,046                   2,910
<CGS>                                                0                       0
<TOTAL-COSTS>                                   25,183                  24,060
<OTHER-EXPENSES>                                     0                       0
<LOSS-PROVISION>                                     0                       0
<INTEREST-EXPENSE>                               7,260                       0
<INCOME-PRETAX>                               (30,392)                (20,600)
<INCOME-TAX>                                         0                       0
<INCOME-CONTINUING>                           (30,392)                (20,600)
<DISCONTINUED>                                       0                       0
<EXTRAORDINARY>                                      0                       0
<CHANGES>                                            0                       0
<NET-INCOME>                                  (30,392)                (20,600)
<EPS-BASIC>                                     (1.60)                  (0.68)
<EPS-DILUTED>                                   (1.60)                  (0.68)


</TABLE>