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## NIOSH HomeNIOSH Pocket Guide to Chemical Hazards **NIOSH Pocket Guide to Chemical Hazards**

• Introduction • Search the Pocket Guide • Chemical Names, Synonyms and Trade Names ◦ A ◦ B ◦ C ◦ D ◦ E ◦ F ◦ G ◦ H ◦ I ◦ J ◦ K ◦ L ◦ M ◦ N ◦ O ◦ P ◦ Q ◦ R ◦ S ◦ T ◦ U ◦ V ◦ W ◦ X ◦ Y ◦ Z • CAS Numbers • RTECS Numbers • Appendices ◦ A - NIOSH Potential Occupational Carcinogens ◦ B - Thirteen OSHA-Regulated Carcinogens ◦ C - Supplementary Exposure Limits Page 1 of 6 CDC - NIOSH Pocket Guide to Chemical Hazards - Toluene -2,4 - diisocyanate

1/20/2015 file:///C:/Program%20Files%20(x86)/Documentum/CTS/docbases/ProDocbase/config/temp_sessions/325272948 ...◦ D - Substances with No Established RELs

◦ E - OSHA Respirator Requirements for Selected Chemicals ◦ F - Miscellaneous Notes ◦ G - 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect ◦ Type C & CE - Definitions for Type C and Type CE Respirators ◦ Personal Protection and Sanitation Codes ◦ First Aid Procedures **NIOSH Homepage**

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# Toluene-2,4-diisocyanate
**Synonyms & Trade Names** TDI; 2,4-TDI; 2,4-Toluene diisocyanate Facebook Reccomend 2 Twitter Tweet 0 Share Compartir
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1/20/2015 file:///C:/Program%20Files%20(x86)/Documentum/CTS/docbases/ProDocbase/config/temp_sessions/325272948 ...**CAS No.** 584-84-9 **RTECS No.**

CZ6300000 **DOT ID & Guide** 2078 156 External Web Site Icon
**Formula** CH 3 C 6H 3 (NCO) 2 **Conversion**

1 ppm = 7.13 mg/m3 **IDLH** Ca [2.5 ppm] See: 584849 **Exposure Limits NIOSH REL**  : Ca See Appendix A **OSHA PEL** † : C 0.02 ppm (0.14 mg/m3 ) **Measurement Methods NIOSH**  2535 Adobe PDF file , 5521 Adobe PDF file , 5522 Adobe PDF file , 5525 Adobe PDF file ; **OSHA** 18 External Web Site Icon , 33 External Web Site Icon , 42 External Web Site Icon See: NMAMor OSHA Methods External Web Site Icon **Physical Description** Colorless to pale-yellow solid or liquid (above 71°F) with a sharp, pungent odor. **MW:** 174.2 **BP:** 484°F MLT: 71° F **Sol:**

Insoluble VP(77°F): 0.01 mmHg **IP:** ? **Sp.Gr:** 1.22 **Fl.P:** 260°F **UEL:** 9.5% **LEL:**

0.9% Class IIIB Combustible Liquid: Fl.P. at or above 200°F. **Incompatibilities & Reactivities** Strong oxidizers, water, acids, bases & amines (may cause foam & spatter); alcohols [Note: Reacts slowly with water to form carbon dioxide and polyureas.] **Exposure Routes** inhalation, ingestion, skin and/or eye contact Page 3 of 6 CDC - NIOSH Pocket Guide to Chemical Hazards - Toluene -2,4 - diisocyanate

1/20/2015 file:///C:/Program%20Files%20(x86)/Documentum/CTS/docbases/ProDocbase/config/temp_sessions/325272948 ...**Symptoms** irritation eyes, skin, nose, throat; choke, paroxysmal cough; chest pain, retrosternal (occurring behind the sternum) soreness; nausea, vomiting, abdominal pain; bronchitis, bronchospasm, pulmonary edema; dyspnea (breathing difficulty), asthma; conjunctivitis, lacrimation (discharge of tears); dermatitis, skin sensitization; [potential occupational carcinogen] **Target Organs** Eyes, skin, respiratory system **Cancer Site** [in animals: pancreas, liver, mammary gland, circulatory sys & skin tumors] **Personal Protection/Sanitation** ( See protection codes) **Skin:** Prevent skin contact **Eyes:** Prevent eye contact **Wash skin:** When contaminated/Daily **Remove:** When wet or contaminated **Change:** Daily **Provide:** Eyewash, Quick drench **First Aid** ( See procedures) **Eye:** Irrigate immediately **Skin:** Soap wash immediately **Breathing:** Respiratory support **Swallow:** Medical attention immediately **Respirator Recommendations NIOSH**  **At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positivepressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus **Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister Any appropriate escape-type, self-contained breathing apparatus Important additional information about respirator selection See also: INTRODUCTION See ICSC CARD: 0339See MEDICAL TESTS: 0233

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1/20/2015 file:///C:/Program%20Files%20(x86)/Documentum/CTS/docbases/ProDocbase/config/temp_sessions/325272948 ...• Link to Us • All Languages • CDC Mobile • Contact CDC USA.gov: The U.S. Government's Official Web Portal Dep artm ent of Centers for Disease Control and Prevention 1600 Clifton Rd. Atlanta, GA 30333, USA 800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO NIOSH All CDC Topics Search The CDC Search A-Z Index for All CDC Topics <a href="http://www.omniture.com" title="Web Analytics"><img src="http://mtrics.cdc.gov/b/ss/cdcgov/1/H.21--NS/0" height="1" width="1" border="0" alt="Web Analytics" /></a> Choose a topic above Page 6of 6 CDC - NIOSH Pocket Guide to Chemical Hazards - Toluene -2,4 - diisocyanate

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