exv10w7






EXHIBIT
10.7



CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT WERE OMITTED AND REPLACED WITH “[***]”. A COMPLETE
VERSION OF THIS EXHIBIT HAS BEEN FILED SEPARATELY WITH THE SECRETARY OF THE SECURITIES AND EXCHANGE
COMMISSION PURSUANT TO AN APPLICATION REQUESTING CONFIDENTIAL TREATMENT UNDER RULE 406 OF THE
SECURITIES ACT OF 1933.




AGREEMENT



WHEREAS, Anthera Pharmaceuticals, Inc., a Delaware corporation having its principal place of
business at 25801 Industrial Blvd., Suite B, Hayward, California 94545, U.S.A. (the “Company”),
Shionogi & Co., Ltd., with a place of business at 1-8, Doshomachi 3-chome, Chuo-ku, Osaka, Japan
(“Shionogi”) and Eli Lilly and Company, an Indiana corporation having its principal place of
business at Lilly Corporate Center, Indianapolis, Indiana 46285, U.S.A. (“Lilly”) entered into the
License Agreement dated July 31, 2006 concerning pharmaceutical products that inhibit phospholipase
(the “License Agreement”);



WHEREAS, Article 3, Section 3(a) of the License Agreement provides for a Milestone Payment by the
Company to Shionogi and Eli Lilly of $3,000,000 upon the initiation of the first Phase 3 clinical
trial of each Licensed Product in an Oral Formulation, fifty percent (50%) or US$1,500,000 of which
is payable to Shionogi (the “Phase 3 Milestone Payment”);



WHEREAS the Company and Shionogi desire to (i) extend the date on which the Phase 3 Milestone
Payment associated with the commencement of Phase 3 clinical trials of varespladib methyl (“A-002”)
is due to Shionogi and (ii) increase the amount of the payment in consideration for such extension;



NOW, THEREFORE, in consideration for the premises and for other good and lawful consideration,
receipt of which is hereby acknowledged, the parties agree as follows.




     1. Terms. Capitalized terms used but not otherwise defined herein shall have the meanings
ascribed to such terms in the License Agreement.



     2. Agreement. Each of the Company and Shionogi agree that (i) the Phase 3 Milestone Payment
associated with the commencement of a Phase 3 clinical trial of A-002 shall be due to Shionogi on
the Payment Date; and (ii) the amount of such Milestone Payment payable to Shionogi shall be
increased from $1,500,000 to $1,750,000. For the purposes of this Agreement, “Payment Date” shall
mean the earliest to occur of (i) twelve (12) months from the enrollment of the first patient in
the first Phase 3 clinical trial of A-002; (ii) [***]; (iii) [***]; (iv) [***]; or (v) [***].



     3. Counterparts; Facsimiles. This Agreement may be executed in one or more counterparts, each
of which shall be an original and all of which shall constitute together the same document. For
purposes of this Agreement and any other document required to be delivered pursuant to this
Agreement, facsimiles of signatures shall be deemed to be original signatures. In addition, if any
of the parties sign facsimile copies of this Agreement, such copies shall be deemed originals.



 









 





     4. Further Acts. Each party agrees to execute, acknowledge and deliver such further
instruments, and to do all such other acts, as may be necessary or appropriate in order to carry
out the purposes and intent of this Agreement.



     5. Other terms and Conditions. All other remaining terms and conditions of the License
Agreement (which relates to Shionogi and Anthera) are unchanged and remain in full force and
effect.



     In witness whereof, the parties have caused this Agreement to be executed by their duly
authorized officers as of the date set forth below.



	 	 	 	 	 	 	 
	Anthera Pharmaceuticals, Inc.	 	Shionogi & Co., Ltd.
	 
	 	 	 	 	 	 
	By:

	 	/s/ Paul Truex
	 	By:
	 	/s/ Yasuhiro Mino
	 

	 	 
	 	 	 	 
	 
	 	 	 	 	 	 
	Name:

	 	Paul Truex
	 	Name:
	 	Yasuhiro Mino
	 
	 	 	 	 	 	 
	Title:

	 	President & Chief Executive Officer
	 	Title:
	 	Director of the Board
Senior Executive Officer
	 
	 	 	 	 	 	 
	Date:

	 	September 7, 2009
	 	Date:
	 	7/9/2009
	 

	 	 
	 	 	 	 






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