**Bifenazate Registrant Focus Meeting**  **Notes** July 24, 2012 , 2:00- 3:00 pm **EPA Participants**  BEAD: Cynthia Doucoure, Donald Atwood, John Faulkner EFED: James Hetrick, Dana Spatz (Branch Chief), Katherine Stebbins HED: Anwar Dunbar, David Hrdy (BC), Kelly Lowe, Anna Lowit, Elizabeth Mendez PRD: Cathryn Britton (Team Leader), Garland Waleko RD: John Hebert, Barbara Madden **Chemtura Participants**  Shaila Rao, Senior Toxicologist Shari Long, Ecotoxicologist Uwe Wanner, Global Manager: Bio/Chemistry Serv ices Roy Russell, Human Exposure Scientist R. Tim Weiland, Registration Specialist **1. Introductions,**  **Registration Review process overview** 

-The p urpose of Reg istration Review is not to re -do the risk assessments completed for registration, but to update the assessments where needed , based on current information .

-W here possible, PRD will coordinate with the current PRIA action. RD has the lead on the PRIA action, and PRD is the lead for Reg istration Review. Regardless of what happens with the PRIA action , Reg istration Review will continue as scheduled.

- Reg istration Review Schedule:  D ocket opens at the end of December 2012, and the Preliminary Work Plan (PWP) publishes identifying what data will likely be needed to update the risk assessment.  The comment period on the P WP closes at the end of Feb 2013.  The Final Work Plan will incorporate comments and will publish in May 2013.  A Data Call - in would go out (following review by other agencies) between January and March 2014.  Study timelines vary (2 -4 years) and the risk assessment will be completed following data submission, which will be followed by a comment period and a final Reg Review decision (2018 - 2020) .  The registrant is encouraged to submit relevant information and/or comments on the PWP during the public comment period.**2. U**  **se ,**  **label clarifications , and EFED data needs** 

- No further clarification needed on BEAD response to registrant comments on the label data table.

- For Homeowner label 400- 517, the application instructions are to mix 1⁄2 teaspoon of the product per gal lon of water . No information is given on the spray volume per area. Chemtura suggested using a finishing spray volume of 400 gal/A, as is indicated on labels 400- 508 and 400- 509, which result s in a rate of 0.5 lb a.i./acre . If Chemtura wishes to include this rate on label 400- 517, this can be discussed with RD .

- EFED data that would be helpful t o fully characterize the parent/degradates and reduce uncertainty include:  Aerobic soil metabolism – EPA only has one study with one soil . Re gistrant will provide EU soil data ( registrant reports parent and degradate - b oth rapidly degrade ) .  Aerobic aquatic metabolism – registrant is currently evaluating the studies conducted for the EU and w ill provide what they have .  Adsorption, desorption of parent compound . Difficult to measure but registrant will look into what data was used for EU registration. Registrant noted that in the past, using worst case assumptions (i.e., K oc=1) has not hit EU triggers despite strict groundwat er standards .  Fish bioaccumulation – registrant does not have this information and will follow up with either a study or a rationale as to why a study is not needed .  Degradates 3598 and 1989 - Both degradates have activity (especially 3589) , registrant will provide batch equilibrium data on 3598 and 1989 .  Ecotox. Studies appear in EU database for both D - 3598 and D - 1989 at: http://sitem.herts.ac.uk/aeru/footprint/en/index.htm . These st udies would be helpful to have ASAP .  Any studies that addres s O CSPP series 835 or 850 guidelines (or the equivalent OECD guidelines ) may be helpful . The registrant will submit what they have . **3. HED and RD up**  **date on PRIA action status**

- HED and RD discussed current PRIA actions with the registrant. **4. Wrap up**  **and Next Steps**

- Preliminary Work Plan (PWP) will be posted when docket opens in December 2012

- Registrant should submit all studies that will assist EPA in completing the PWP to Garland Waleko in PRD, waleko.garland@epa.gov .

- All information related to the current PRIA action should be submitted to the R D Project Manager, John Hebert, hebert.john@epa.gov .