Draft for Comment Version – March 1, 2014

Appendix D: Registration Review Chemical 

Volatilization Screening Analysis Results

Office of Pesticide Programs

Office of Chemical Safety and Pollution Prevention

U.S. Environmental Protection Agency

Washington, DC

March 1, 2014
Draft for Comment Version – March 1, 2014

2

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

2,4-D Yes No

2,4-DB No No

2,4-DP N/A No food/feed uses (golf course, rights-of-way uses). No 

screen performed at this time.

2-EEEBC N/A Tree injection on ornamental trees formulated as an 

enclosed compressible capsule

4-Aminopyridine N/A Granular bait. No screen performed at this time.

Abamectin No No

Acephate Yes Yes Cole and row scenarios exceed COC at 20 acre and larger 

fields.

Acequinocyl No No

Acetaminophen N/A One use to kill snakes via stuffed parachuted mice in 

Guam. No screen performed at this time.

Acetic acid, and salts N/A

Scoping document indicated a quantitative assessment not 

likely, no data called in, qualitative or existing assessments 

adequate...no screen performed at this time.

Acetochlor No No

Acibenzolar No Maybe Distance to COC is 289 and 456 meters only for 60 and 80 

A fields

Acrolein N/A

Aquatic herbicide. No screen performed at this time. 

Note: acrolein is known to volatilize from treated water 

and multiple air monitoring studies are available.

Alachlor No No

Aldicarb N/A All uses have been cancelled. No screen performed at this 

time.

Aldoxycarb N/A All uses have been cancelled. No screen performed at this 

time.

Aliette No No

Aliphatic alcohols, C6-C16 N/A

Based on the lack of food and residential uses and low 

hazard via the oral, dermal, and inhalation routes of 

exposure, quantitative exposure assessments have not been 

conducted. No screen performed at this time.

Aliphatic esters N/A

Based on the lack of hazard concern and the metabolic 

profile of the methyl esters of fatty acids, toxicological 

endpoints have not been identified for risk assessment 

purposes. Therefore, quantitative assessments have not 

been conducted. No screen performed at this time.

Aliphatic solvents N/A Based on the lack of hazard concern for the aliphatic 

alcohols and esters, no screen performed at this time.

Allethrin stereoisomers N/A Allethrins have no agricultural uses (indoor, mosquito 

uses). No screen performed at this time.

alpha-Chlorohydrin N/A

Rodenticide bait product in poly-paper sachets, which are 

then placed in tamper-proof bait boxes. No screen 

performed at this time.

Aluminum phosphide N/A Commodity Fumigant. No screen performed at this time.
Draft for Comment Version – March 1, 2014

3

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Ametoctradin N/A No hazard or points of departure selected

Ametryn No No

Amicarbazone No No

Aminocyclopyrachlor N/A No agricultural uses (except rangeland). No screen 

performed at this time.

Amitraz N/A Livestock (dip, ear tag) and pet use only. No screen 

performed at this time.

Amitrole N/A No agricultural uses (industrial areas, right-of-way uses). 

No screen performed at this time.

Ancymidol N/A No agricultural uses (greenhouse uses). No screen 

performed at this time.

Antimycin A N/A Used as a piscicida. No screen performed at this time.

Aquashade (*) N/A Used as an aquatic algaecide/herbicide. No screen 

performed at this time.

Atrazine No Yes Soil scenario exceeds COC at all field sizes.

Azinphos-Methyl N/A Voluntarily cancelled. No screen performed at this time.

Azoxystrobin No No

Benfluralin No No

Bensulfuron No No

Bensulide No No

Bentazon No No

Benthiavalicarb-isopropyl N/A Import uses only. No screen performed at this time.

Benzoic acid N/A No registered conventional pesticide uses. No screen 

performed at this time.

Benzyl benzoate N/A No agricultural uses (indoor, pet uses). No screen 

performed at this time.

Bifenazate Yes No

Bifenthrin No No

Bispyribac-sodium No No

Bitrex N/A

EPA is not opening a docket for Bitrex because this 

pesticide is not included in any products actively registered 

under FIFRA section 3. No screen performed at this time.

Boscalid No No

Brodifacoum N/A Rodenticide bait. No screen performed at this time.

Bromacil No No

Bromadiolone N/A Rodenticide bait. No screen performed at this time.

Bromethalin N/A Rodenticide bait. No screen performed at this time.

Bromoxynil and esters No Maybe Distance to COC is greater than 100 meters at 60 acres 

fields and above for cole and row crops.

Bromuconazole N/A No agricultural uses; only use is on roses. No screen 

performed at this time.
Draft for Comment Version – March 1, 2014

4

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Buprofezin No Yes Cole and orchard crops exceed at all field sizes.

Butralin Yes No

Butylate No Yes Soil scenario exceed COC at all field sizes. Incorporated 

so this may be conservative.

Cacodylic acid, and salts N/A All uses cancelled. No screen performed at this time.

Captan Yes Yes

Carbaryl No No Note: have inhalation study and dose is similar to oral 

study so no extra 10X for screen using oral study.

Carbofuran N/A All uses have been cancelled. No screen performed at this 

time.

Carbon and CO2 N/A

No agricultural uses. Used for fumigation (gaseous 

products are generated by oxidation of carbonaceous 

materials within flare like containers to form carbon 

dioxide) of coyotes, red foxes, striped skunks, 

woodchucks, yellow-bellied marmots, ground squirrels, 

prairie dogs, moles, gophers, rats. Use sites include lawns, 

parks, golf courses, rangeland, reforested areas, open 

fields, meadows, and non-crop areas.

Carfentrazone-ethyl No No

Chlorantraniliprole (E2Y45) N/A

Based on the lack of hazard identified in the acute 

inhalation study, lack of acute irritation, and extremely low 

oral toxicity, no inhalation endpoint was selected for 

quantitative risk assessment. No screen performed at this 

time.

Chlorethoxyfos Yes Yes

Chlorfenapyr N/A

Chlorfenapyr has no outdoor agricultural uses. Current 

food uses include fruiting vegetable crop group 8 (limited 

to those grown in greenhouses).

Chlorflurenol N/A No agricultural uses (turf, ornamental uses). No screen 

performed at this time.

Chlormequat Chloride N/A No outdoor or agricultural uses (plant growth regulator 

used in green houses)

Chloroneb N/A Seed treatment uses. No screen performed at this time.

Chlorophacinone N/A Rodenticide bait. No screen performed at this time.

Chloropicrin N/A Fumigant

Chlorothalonil Yes Yes Inhalation POD based on acute LC50 rat inhalation study

Chlorpropham No Yes Only “agricultural” use is Easter lilies which are only 

grown in Norther CA and Southern OR

Chlorpyrifos Yes Yes Cole, row, orchard crops exceed COC at all field sizes.

Chlorpyrifos-methyl N/A

Grain/Cereal/Seed/Flour Bin and Warehouse Storage 

Treatment are the only uses. No screen performed at this 

time.
Draft for Comment Version – March 1, 2014

5

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Chlorsulfuron No No

Cholecalciferol N/A Rodenticide bait. No screen performed at this time.

Clethodim No No

Clodinafop-propargyl No No

Clofencet No No No short-term inhalation endpoint identified. Use Chronic 

oral toxicity in the dog for screen

Clofentezine No No

Clomazone No No

Clopyralid No No

Cloransulam N/A An inhalation endpoint was not established. 

Clothianidin No No

Coppers N/A No endpoints of toxicological concern have been identified 

for risk assessment purposes 

Coumaphos N/A No agricultural crop uses. Use on cattle and as a pest strip 

in beehives

Cryolite N/A No inhalation toxicity endpoint currently. No screen 

performed at this time.

Cyazofamid No No

Cyclanilide No No

Cyfluthrins Yes No

Cyhalofop-butyl No No

Cyhexatin N/A Currently No Registrations, No scoping document done... 

No screen performed at this time.

Cymoxanil No No

Cypermethrin Yes No

Cyphenothrin N/A

Current uses are only indoor premise treatments or direct 

applications to pets. No agricultural uses registered. No 

screen performed at this time.

Cyproconazole No No

Cyprodinil No No

Cyromazine Yes No

Daminozide (Alar) No Yes

Dazomet N/A Fumigant

DCNA No Yes Cole and row scenarios exceed COC at 20 acre field sizes 

and larger.

DCPA No No

DDVP (Dichlorvos) N/A No agricultural uses (indoor uses). No screen performed at 

this time.

Deet N/A No agricultural uses (personal repellent). No screen 

performed at this time.

Deltamethrin No No
Draft for Comment Version – March 1, 2014

6

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Denatonium saccharide N/A Qualitative Reg Review Risk Assessment....No screen 

performed at this time.

Desmedipham No No

Diazinon Yes Yes Cole, row, orchard scenarios exceed COC at all field sizes.

Dicamba No Maybe Cole and row scenarios exceed COC at 40 acre field sizes 

and larger.

Dichlobenil Yes Yes Row and orchard scenarios exceed COC at all field sizes.

Dicofol No No

Dicrotophos Yes Yes Distance to COC exceeds 4500 meters for all crops at all 

field sizes.

Difenacoum N/A Rodenticide bait. No screen performed at this time.

Difenoconazole No No

Difenzoquat N/A Voluntarily cancelled...No screen performed at this time.

Difethialone N/A Rodenticide bait. No screen performed at this time.

Diflubenzuron Yes No

Diflufenzopyr No No

Dikegulac Sodium N/A

No agricultural uses (plant growth regulator for 

greenhouses and nurseries). No screen performed at this 

time.

Dimethenamid No Yes Cole and soil scenarios exceed COC at all field sizes.

Dimethoate Yes Yes Inhalation study used; Cole, Row and Orchard scenarios 

exceed COC at all field sizes.

Dimethomorph No No

Dimethyl Disulfide N/A Fumigant

Dinotefuran N/A

No systemic toxicity was seen in a 28-day inhalation 

toxicity study at doses that were in ~ 10,000-fold excess of 

the highest anticipated human exposure. There are no 

developmental toxicity concerns. No screen performed at 

this time.

Dioctylsulfosuccinates N/A

Based on the low toxicity of DSS and its use as a 

pharmaceutical drug administered in much higher doses 

than would result from any pesticide exposures, a 

quantitative human health risk assessment is not required 

under registration review for the existing uses of DSS. No 

screen performed at this time.

Diphacinone, and salts N/A Rodenticide bait. No screen performed at this time.

Dipropyl isocinchomeronate N/A No ag uses, only insecticide repellent in personal products 

and pet products. No screen performed at this time.

Diquat Dibromide Yes Yes

Dithianon N/A Import uses only. No screen performed at this time.
Draft for Comment Version – March 1, 2014

7

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Diuron No No

d-Limonene N/A

d-Limonene is not registered for terrestrial food or feed 

crop uses as an active ingredient. Overall, the database 

supports the conclusion that high doses of d-limonene 

(≥500 mg/kg/day) are needed to induce any form of 

relevant toxicity in laboratory animals.

Dodine No No

Emamectin Benzoate No Maybe Distance to COC is greater than 100 meters at 60 acres 

fields and above for cole crops.

Endosulfan N/A Scheduled for cancellation

Endothall, and salts No Yes

Cole and row scenarios exceed COC at all field sizes. 

Note mostly aquatic herbicide but dessicant uses on 

cotton/potatoes and sucker reduction use on hops.

Epoxiconazole N/A Import uses only. No screen performed at this time.

EPTC Yes Yes Cole, Row scenarios exceed COC at all field sizes.

Esfenvalerate No Maybe Row scenario exceeds COC at 60 acre field sizes and 

larger.

Ethaboxam N/A No agricultural uses (import and seed treatment uses only). 

No screen performed at this time.

Ethalfluralin No Yes Soil, Cole, and Row scenarios exceed COC at all field 

sizes.

Ethametsulfuron N/A

Only import tolerances will be supported during 

registration review. The case is to be closed, and no 

additional work will be conducted. No screen performed 

at this time.

Ethephon No No

Ethiprole N/A No agricultural uses in US (imported rice and tea uses 

only)

Ethofumesate No Yes Soil scenarios exceed COC at all field sizes.

Ethoprop No Yes Soil scenario exceeds COC at all field sizes. Incorporated 

so this may be conservative.

Ethylene oxide N/A Commodity Fumigant....No screen performed at this time.

Etofenprox Yes No

Etoxazole No No

Fenamidone No No

Fenamiphos N/A There are currently no registrations for fenamiphos in the 

U.S. (import tolerances only).

Fenarimol No No

Fenazaquin No No

Fenbuconazole No No

Fenbutatin Oxide (Vendex) No No

Fenhexamid N/A

The HIARC determined that a separate inhalation risk 

assessment was not required for short- and intermediateterm inhalation risk assessments
Draft for Comment Version – March 1, 2014

8

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Fenitrothion N/A

No agricultural uses. Only one import tolerance in wheat 

gluten and USA registered uses for ant and roach bait 

traps. No screen performed at this time.

Fenoxaprop-p-ethyl Yes No

Fenoxycarb N/A No agricultural uses (fire ant bait on turf). No screen 

performed at this time.

Fenpropathrin No Maybe Distance to COC is 62 meters only for 120 A fields for 

row crops.

Fenpyroximate Yes No

Fenvalerate N/A

Fenvalerate is not included in any products actively 

registered under FIFRA section 3. No screen performed 

at this time.

Ferbam No Yes Cole scenario exceeds COC at 20 acre field sizes and 

larger.

Fipronil N/A No agricultural uses (indoor, pet, turf, ornamental uses). 

No screen performed at this time.

Flazasulfuron No No

Flonicamid No No

Florasulam No No

Florasulam No No

Fluazinam Yes No

Flubendiamide No No

Flucarbazone-sodium Yes No

Fludioxonil No No

Flufenacet No No

Flufenoxuron N/A Import uses only. No screen performed at this time.

Flumethrin N/A No agricultural uses (pet collar use)

Flumetralin No No

Flumetsulam No Maybe Soil scenario exceeds COC at 20 acres and larger

Flumeturon No No

Flumiclorac-pentyl No No

Flumioxazin No Maybe

Fluometuron No No

Fluopicolide No No

Fluoxastrobin No No

Fluridone N/A Aquatic Herbicide, no agricultural uses. No screen 

performed at this time.

Fluroxypyr,1-

methylheptylester No No
Draft for Comment Version – March 1, 2014

9

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Flurprimidol N/A No agricultural uses (turf, ornamental, greenhouse uses). 

No screen performed at this time.

Fluthiacet-methyl No No

Flutolanil N/A No appropriate endpoint was identified in the database. 

No screen performed at this time.

Flutriafol No No

Folpet No No

Fomesafen No Yes Soil scenario exceed COC at all field sizes.

Foramsulfuron N/A

There were no effects observed in any of the toxicity 

studies with the chemical, and therefore no endpoints for 

risk assessment were selected. No screen performed at this 

time.

Formetanate HCl No Yes Row and orchard scenarios exceed COC at all field sizes.

Fosamine ammonium N/A

Fosamine ammonium is an herbicide applied to nonagricultural rights-of way, industrial sites, fencerows, and 

pine plantations. No screen performed at this time.

Fosthiazate Yes Yes Row scenarios exceed COC at all field sizes.

Furfural N/A Soil fumigant like. No screen performed at this time.

Gamma Cyhalothrin Yes No

Glufosinate Yes No

Glyphosate N/A

Based on the lack of toxicity up to the highest 

concentration tested (0.36 mg/L) in the 28-day inhalation 

toxicity study in rats, the quantification of inhalation risks 

is not required.

Halfenozide N/A No agricultural uses (turf uses). No screen performed at 

this time.

Halosulfuron No No

Hexaflumron N/A

The only registered use for hexaflumuron is as a bait 

station/bait application for elimination of subterranean 

termite colonies. Due to the low human exposure potential 

(i.e., bait station/bait application only), many toxicological 

study requirements were waived for hexaflumuron.

Hexazinone No No

Hexythiazox No No

Hydramethylnon N/A All end-use products are gel baits, bait stations, or granular 

products. No screen performed at this time.

Hydrogen Cyanamide Yes No

Hymexazol N/A Commercial Seed Treatment only - sugar beets. No screen 

performed at this time.

Imazalil N/A

Uses are for postharvest treatment of citrus fruits and 

bananas (foreign use on imported RAC only) and for seed 

treatment of barley and wheat. No screen performed at this 

time.

Imazamethabenz No No
Draft for Comment Version – March 1, 2014

10

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Imazamox N/A

In a meeting held on 12-JUN-2001, the Hazard 

Identification Assessment Review Committee (HIARC) 

determined that the toxicological profile of imazamox 

supports a tolerance exemption for this chemical as no 

adverse effects were observed in the submitted 

toxicological studies regardless of the route of exposure

Imazapic No No

Imazapyr No No

Imazaquin No No

Imazethapyr No No

Imidacloprid No No

Imiprothrin N/A No agricultural uses (indoor, non-food use). No screen 

performed at this time.

Indaziflam No No

Indoxacarb Yes No

Inorg. chlorates N/A

Vapor pressure is classified as zero. Volatilization is 

expected to be negligible. No screen performed at this 

time.

Inorg. nitrate/nitrite N/A

HED does not believe that new data are needed for 

Registration Review and that existing risk assessments will 

support Registration Review. There are no pesticidal food 

uses. No screen performed at this time.

Inorg. polysulfides N/A

Calcium polysulfide readily breaks down in calcium 

hydroxide and sulfur in the human body. These chemicals 

are assessed separately. No screen performed at this time.

Inorg. thiosulfates N/A All products voluntarily cancelled. No screen performed 

at this time.

Inorganic sulfites (Sulfur 

Dioxide) N/A

Fumigant: These products are used in cold-storage 

warehouses, trucks, vans and train cars for post-harvest 

grape fumigation. No screen performed at this time.

Iodomethane (Methyl Iodide) N/A Soil fumigant. No screen performed at this time.

Iodosulfuron-methyl No No

Ipconazole N/A Only use is for seed treatment. No screen performed at 

this time.

Iprodione No No

Iron salts N/A De minimus - qualitative risk assessment. No screen 

performed at this time.

Isoxaben No No

Kasugamycin No No

Kresoxim-methyl N/A Inhalation risk assessments were not previously required. 

No screen performed at this time.

Lactofen No No

Lambda Cyhalothrin Yes No
Draft for Comment Version – March 1, 2014

11

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Linuron No Yes Soil, cole, and row scenarios exceed COC at all field sizes.

Macleaya Extract N/A

Macleaya extract is a plant extract used as ornamental 

plant fungicide in enclosed commercial greenhouses. No 

screen performed at this time.

Magnesium phosphide N/A Commodity Fumigant....No screen performed at this time.

Malathion Yes No

Maleic Hydrazide No No Inhalation study under review

Mammalian Gonadotropin 

Releasing Hormone N/A Deer vaccine. No screen performed at this time.

Mandipropamid No No

Maneb N/A Inactive labels: No section 3 registered uses. No screen 

performed at this time.

MCPA No Yes Soil and cole/cotton scenarios exceed COC at most field 

sizes.

MCPB, and salts No No

Mecoprop (MCPP) N/A No food/feed uses (turf, industrial area uses). No screen 

performed at this time.

Mefluidide, and salts N/A No agricultural uses (ornamental plant growth regulator). 

No screen performed at this time.

Mepiquat chloride and 

mepiquat pentaborate No No

Meptyldinocap N/A Import uses only. No screen performed at this time.

Mesotrione No No

Metaflumizone No No

Metalaxyl No Maybe Distance to COC is greater than 100 meters at 60 acres 

fields and above for cole and row crops.

Metaldehyde No No

Metam Sodium N/A Fumigant

Metconazole No No

Methamidophos Yes Yes Cole and row scenarios exceed COC at all field sizes.

Methidathion N/A Cancelled

Methiocarb N/A

No agricultural uses (Use on ornamentals, lawns, and nonbearing deciduous and nut trees and lawn and ornamental 

use in residential setting is solid bait formulation only). 

No agricultural uses. No screen performed at this time.

Methomyl Yes No

Methoxyfenozide No No

Methyl bromide N/A Methyl bromide is a soil fumigant/commodity fumigant. 

No screen performed at this time.

Methyl parathion N/A Voluntarily cancelled during Registration Review.

Metofluthrin N/A No agricultural uses (indoor, personal mosquito uses). No 

screen performed at this time.

Metolachlor & s-Metolachlor Maybe Cole and row scenarios exceed COC at 60 acre field sizes 
Draft for Comment Version – March 1, 2014

12

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

and larger.

Metrafenone No No

Metribuzin Yes No

Metsulfuron No Maybe Row scenario exceeds COC at 40 acre field sizes and 

larger.

Metsulfuron No No

Mevinphos N/A No currently registered products. No screen performed at 

this time.

MGK-264 N/A No agricultural uses (indoor, pet, turf, and ornamental 

uses). No screen performed at this time.

Milbemectin N/A No agricultural uses (ornamentals). No screen performed 

at this time.

MITC N/A Fumigant

MSMA Yes No

Myclobutanil No No

Naled Yes Yes Distance to COC exceeds 4500 meters for all crops at all 

field sizes.

Naphthalene N/A No agricultural uses (animal and moth repellent). No 

screen performed at this time.

Napropamide No No

Neodecanamide, N-methyl- N/A No agricultural uses (household insect repellent). No 

screen performed at this time.

Nicarbazin N/A No agricultural uses (goose bait). No screen performed at 

this time.

Niclosamide N/A

Niclosamide is used by the U.S. Fish and Wildlife Service 

(USFWS) to control the sea lamprey population in the 

Great Lakes region of the United States. Occupational 

assessment was performed for dermal only. No screen 

performed at this time.

Nicosulfuron No No

Nitrapyrin No Yes Row scenarios exceed COC at all field sizes.

Norflurazon No No

Novaluron No No

Orthosulfamuron No No

Oryzalin No No

Oxamyl Yes No

Oxydemeton-methyl Yes No

Oxytetracycline N/A

Based on information obtained in the web it is estimated to 

be 9.7x10-25 mmHg. No inhalation toxicity studies are 

available and endpoints have not been selected for a 

quantitative occupational assessment. No screen 

performed at this time.
Draft for Comment Version – March 1, 2014

13

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Paclobutrazol N/A

No agricultural use (turf, outdoor ornamentals, greenhouse 

ornamentals and bulb soaks). No screen performed at this 

time.

Paraquat dichloride Yes Yes

PCNB No Yes Cole, Row, Orchard and Soil scenarios exceed COC at all 

field sizes

p-Dichlorobenzene N/A No agricultural uses (indoor uses only). No screen 

performed at this time.

Pendimethalin No Yes Soil, Cole, Row, and Orchard scenarios exceed COC at all 

field sizes

Penoxsulam No No

Permethrin Yes No

Phenmedipham No No

Phenothrin (Sumithrin) N/A

Phenothrin is not currently registered for direct application 

to agricultural crops (indoor, pet, mosquito uses). No 

screen performed at this time.

Phorate No Yes

Soil scenario exceed COC at all field sizes. Note: 

Granular products only. All applications soil 

incorporated. Screen is likely very conservative.

Phosalone N/A No registered products. No screen performed at this time.

Phosmet No Yes Cole and row scenarios exceed COC at all field sizes.

Phosphine N/A Commodity Fumigant. No screen performed at this time.

Picaridin N/A

The active ingredient is only used as a repellent, directly 

applied to skin; there are no registered ag. uses. No screen 

performed at this time.

Picloram No No

No inhalation endpoints were chosen in the original risk 

assessment (1994) because it was not required because “no 

endpoints were identified for either the oral or dermal 

routes for short and intermediate term exposures that could 

be extrapolated to the inhalation route of exposure”. 

Screen used lowest NOAEL from an oral study with short 

term duration.

Piperalin N/A

Qualitative assessment since only niche use on roses in 

greenhouses, HASPOC waived tox requirements, PPE 

required on labels. No screen performed at this time.

Piperonyl butoxide Yes No

Pirimicarb N/A No active registrations. No screen performed at this time.

Pirimiphos-methyl N/A The only use pattern is post-harvest, on stored grains. No 

screen performed at this time.

Polypropylene glycol N/A No agricultural uses (livestock insect repellent). No screen 

performed at this time.

Prallethrin N/A No agricultural uses (indoor, mosquito). No screen 

performed at this time.

Primisulfuron-methyl No No

Prodiamine No No Screen performed for sod farm use. No agricultural uses.

Profenofos Yes No
Draft for Comment Version – March 1, 2014

14

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Prohexadione calcium No No

Prometon N/A No agricultural uses (industrial sites, spot turf treatment). 

No screen performed at this time. 

Prometryn No No

Pronamide (Propyzamide) No No

Propachlor No Yes Soil scenarios exceed COC at all field sizes.

Propamocarb No No

Propanil No No

Propargite Yes No

Propazine No Maybe Soil scenario exceed COC at 60 acre field sizes and larger.

Propetamphos N/A Voluntarily cancelled during Registration Review.

Propiconazole No No

Propionic acid, and salts N/A No agricultural uses (stored grain uses, poultry litter uses). 

No screen performed at this time. 

Propoxur N/A Not for use on agricultural settings (only for FHE).

Propoxycarbazone-sodium No No

Propylene oxide N/A Commodity Fumigant....No screen performed at this time.

Prosulfuron No No

Prothioconazole No No

Pymetrozine No No

Pyraclostrobin Yes No

Pyraflufen-ethyl No No

Pyrasulfotole No No

Pyrethrin and derivatives Yes Maybe Cole and row scenarios exceed COC at 40 acre field sizes 

and larger.

Pyridaben Yes Maybe Distance to COC is greater than 100 meters at 40 acres 

fields and above for cole crops.

Pyridalyl No No

Pyridate No No

Pyrimethanil No Maybe Cole scenario exceeds COC at 40 acre field sizes and 

larger.

Pyriproxyfen N/A

Based on the absence of biologically relevant toxicity at 

the LOAEL of 1.0 mg/L, the quantification of inhalation 

risks is not required. In addition, no developmental 

concerns (toxicity) were seen in either rats or rabbits. 

Pyrithiobac No No Chronic dietary POD used for screen as no inhalation POD 

has been previously selected

Pyroxsulam No No

Quinclorac No No

Quinoxyfen No No

Quizalofop No No
Draft for Comment Version – March 1, 2014

15

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Resmethrin N/A

There are no registered agricultural applications for 

resmethrin (wide-area mosquito abatement). No screen 

performed at this time.

Rimsulfuron No No

Rotenone N/A Piscicide use only. No screen performed at this time.

Rotenone N/A

Termination of rotenone uses that include formulations for 

livestock use, residential and homeowner uses, domestic 

pet uses, and all other uses, except for the piscicide uses

Saflufenacil No No

Sethoxydim Yes No

Siduron N/A No agricultural uses (turf uses only). No screen performed 

at this time.

Silica and silicates N/A De minimus - qualitative risk assessment. No screen 

performed at this time.

Simazine No Maybe Soil scenario exceed COC at 40 acre field sizes and larger.

Soap salts N/A De minimus - qualitative risk assessment. No screen 

performed at this time.

Sodium acifluorfen No No

Sodium Benzoate N/A No registered conventional pesticide uses. No screen 

performed at this time.

Sodium Bisulfite N/A Postharvest fumigant. No screen performed at this time.

Sodium cyanide N/A No agricultural uses (capsule use only). No screen 

performed at this time.

Spinetoram No No

Spinosad No No

Spirodiclofen No No

Spiromesifen Yes No

Spirotetramat No No

Spiroxamine Yes No

Starlicide N/A There are no registered agricultural uses for starlicide. No 

screen performed at this time.

Streptomycin N/A Solid (vapor pressure not determined). No screen 

performed at this time.

Strychnine N/A No agricultural uses (rodenticide). No screen performed at 

this time.

Sulfentrazone No No

Sulfluramid N/A Bait stations, granular applications forestry. No screen 

performed at this time.

Sulfometuron-methyl N/A No agricultural uses (forestry, rights-of-way uses). No 

screen performed at this time.

Sulfosate No No

Sulfosulfuron No No
Draft for Comment Version – March 1, 2014

16

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Sulfur N/A Qualitative Reg Review Risk Assessment, Low tox and 

low exposure...No screen performed at this time.

Sulfuryl Fluoride N/A Current uses are structural/commodity fumigation. No 

screen performed at this time.

Tanol derivs. N/A

These compounds are widely used as food additives and 

fragrances, are naturally occurring, are present in 

registered pesticide products at very low levels and likely 

to result in very low exposures from pesticidal uses. No 

screen performed at this time.

Tau-fluvalinate N/A No agricultural uses (ornamentals, bee hives, ant mound 

uses). No screen performed at this time.

Tebuconazole No No

Tebufenozide No No

Tebufenpyrad N/A Label specifies “Ornamental Crops Grown in Commercial 

Greenhouses”. No screen performed at this time.

Tebupirimiphos 

(Phostebupirim) Yes Yes Soil , Row scenarios exceed COC at all field sizes

Tebuthiuron N/A No agricultural uses (pastureland/rangeland, non-crop 

industrial area uses). No screen performed at this time.

Tefluthrin Yes Maybe

Soil scenario exceeds COC at all field sizes however Atplanting is band or in-furrow application. At-cultivation is 

a split-boot treatment directed to the base of the seedling at 

both sides of the row (lay-by treatment). 

Telone (1,3-D) N/A 1,3-D is a soil fumigant fumigant. No screen performed at 

this time.

Tembotrione No No

Tepraloxydim No No

Terbacil No Maybe Distance to COC is 147 meters only for 120 A fields

Terbufos Yes Yes

Soil scenario exceed COC at all field sizes. Note: 

Granular products only. All applications soil 

incorporated. Screen is likely very conservative.

Tetrachlorvinphos N/A No agricultural uses (livestock uses). No screen performed 

at this time.

Tetraconazole Yes Yes No NOAEL in 28-day rat inhalation tox study

Tetradifon N/A No registered uses. No screen performed at this time.

Tetramethrin N/A

Tetramethrin is not currently registered for direct 

application to agricultural crops (indoor, ornamentals). No 

screen performed at this time.

TFM/Lamprecide N/A

TFM is used by the U.S. Fish and Wildlife Service 

(USFWS) to control the sea lamprey population in the 

Great Lakes region of the United States. No screen 

performed at this time.

Thiabendazole, and salts N/A No agricultural uses (seed treatment uses). No screen 

performed at this time.
Draft for Comment Version – March 1, 2014

17

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Thiacloprid Yes No

Thiamethoxam No No

Thiazopyr No Yes

Note: no inhalation endpoints were chosen in the original 

risk assessment (1997) because “a short- or intermediateterm risk assessment is not required because no endpoints, 

indicating potential for adverse effects, were identified”. 

Screen used lowest NOAEL from an oral study with short 

term duration.

Thidiazuron No No

Thiencarbazone No No

Thifensulfuron-methyl No No

Thiobencarb No Yes Soil scenario exceed COC at all field sizes.

Thiodicarb Yes Yes Cole and row scenarios exceed COC at all field sizes. 

Note: Inhalation study is on dust formulation.

Thiophanate-methyl No Maybe Distance to COC is greater than 100 meters at 40 acres 

fields and above for cole and row crops.

Tolfenpyrad No No

Topramezone No No

TPTH (Triphenyltin 

hydroxide) Yes Yes Cole and row scenarios exceed COC at all field sizes. 

Orchard exceed COC at 40 acre field sizes and larger.

Tralkoxydim No No

Triadimefon No Maybe Distance to COC is 119 meters at 80 acre field only for 

orchards.

Triallate No Yes Soil scenario exceed COC at all field sizes.

Triasulfuron No No

Tribenuron-methyl No No

Tribufos (DEF) Yes No

Trichlorfon N/A No agricultural uses (ornamental, turf uses). No screen 

performed at this time.

Triclopyr, salts and esters No Maybe Distance to COC is 38 and 180 meters only for 80 and 120 

A fields

Trifloxystrobin No No

Trifloxysulfuron-sodium No No

Triflumizole No Maybe Cole scenarios exceed COC at 40 acre field sizes and 

larger.

Trifluralin Yes Maybe Soil scenario exceeds COC at 20 acres and larger

Triflusulfuron No No

Triforine N/A No agricultural uses (ornamental and import only). No 

screen performed at this time.

Trinexapac-ethyl No No

Triticonazole N/A No agricultural uses other than seed treatment. No screen 

performed at this time.
Draft for Comment Version – March 1, 2014

18

Appendix Table D1: Summary of Volatilization Screen

Chemical Inhalation Tox 

Study

Needs flux 

study based 

on screen?

Comments

Undecylenic Acid N/A

No food uses - use in pet shampoos and sprays. Based on 

the low toxicity of undecylenic acid and its use as a 

pharmaceutical drug administered in higher doses than 

would result from any pesticide exposures, a quantitative 

human health risk assessment is not required under 

registration review for the existing uses of undecylenic 

acid. No screen performed at this time.

Uniconazole No No

Urea N/A Qualitative Reg Review Risk Assessment, 2005 TRED 

Qualitative, Low tox... No screen performed at this time. 

Vinclozolin N/A No agricultural uses currently registered (turf uses). No 

screen performed at this time.

Warfarin N/A Rodenticide/ no agricultural uses

Xylene (Aromatic solvents) N/A Aquatic herbicide use only. No screen performed at this 

time.

Zinc Phosphide N/A

Inhalation endpoints for zinc phosphide have not been 

selected and/or established and therefore quantitative 

occupational assessment has not been conducted. No 

screen performed at this time.

Zoxamide No No