[Federal Register Volume 65, Number 81 (Wednesday, April 26, 2000)]
[Notices]
[Page 24490]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-10403]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Proposed Collection; Comment Request; a Nested Case-Control Study 
of Lung Cancer and Diesel Exposure Among a Cohort of Non-Metal Miners

SUMMARY: In compliance with the requirement of Section 3506(c)(2)(A) of 
the Paperwork Reduction Act of 1995, for opportunity for public comment 
on proposed data collection projects, the National Cancer Institute 
(NCI), the National Institutes of Health (NIH) will publish periodic 
summaries of proposed projects to be submitted to the Office of 
Management and Budget (OMB) for review and approval.

PROPOSED COLLECTION: Title: A Nested Case-Control Study of Lung Cancer 
and Diesel Exhaust Among a Cohort of Non-Metal Miners. Type of 
Information Collection Request: New. Need and Use of Information 
Collection: This nested case-control study will examine lung cancer in 
non-metal miners and its association, if any, with diesel exhaust 
exposure. The study will involve approximately 160 deaths from lung 
cancer (the actual number will depend on the number of deaths 
occurring,but based on national rates we expect 160), and four controls 
matched to each death, identified from the cohort. Controls will be 
matched on mine, gender, race/ethnicity and year of birth (within 5 
years). Detailed information regarding exposure to diesel exhaust will 
be obtained from employment records and measurements of diesel exhaust 
surrogates. Information on potential confounders will be obtained by 
interview and from environmental measurements. This information will be 
used in a study by the National Cancer Institute and the National 
Institute for Occupational Safety and Health to examine risk of 
mortality from lung cancer for various measures of diesel exhaust 
exposure, adjusted for smoking and other potential confounders. 
Frequency of Response: One-time study. Affected Public: Individuals. 
Type of Respondents: Workers or next of kin of workers. The annual 
reporting burden is as follows: Estimated number of Respondents: 227; 
Estimated Number of Responses per Respondent: One; Average Burden Hours 
per Response: 1.0; and Estimated Total Annual Burden Hours Requested: 
227. There are no Capital Costs, Operating Costs, and/or Maintenance 
Costs to report.

REQUEST FOR COMMENTS: Written comments and/or suggestions from the 
public and affected agencies are invited on one or more of the 
following points: (1) Whether the proposed collection or information is 
necessary for the proper performance of the function of the agency, 
including whether the information will have practical utility; (2) The 
accuracy of the agency's estimate of the burden of the proposed 
collection of information, including the validity of the methodology 
and assumptions used; (3) Ways to enhance the quality, utility, and 
clarity of the information to be collected; and (4) Ways to minimize 
the burden of the collection of information on those who are to 
respond, including the use of appropriate automated, electronic, 
mechanical, or other technological collection techniques or other forms 
of information technology.

FOR FURTHER INFORMATION CONTACT: To request more information on the 
proposed project or to obtain a copy of the data collection plans and 
instruments, contact Dr. Debra Silverman, NCI Project Director, 
National Cancer Institute, Executive Plaza South, Room 8108, Rockville, 
Maryland 20892-7240, or call non-toll-free number (301) 435-4716, or 
FAX your request to (301) 402-1819, or E-mail your request, including 
your address, to <a href="/cdn-cgi/l/email-protection#2a7943465c4f58474e6a4f5249424b444d4f04444342044d455c"><span class="__cf_email__" data-cfemail="ffac9693899a8d929bbf9a879c979e91989ad1919697d1989089">[email protected]</span></a>.

COMMENTS DUE DATE: Comments regarding this information collection are 
best assured of having their full effect if received on or before June 
26, 2000.

    Dated: April 18, 2000.
Reesa Nichols,
NCI Project Clearance Liaison.
[FR Doc. 00-10403 Filed 4-25-00; 8:45 am]
BILLING CODE 4140-01-M


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