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Exhibit 10.22
  ASSET PURCHASE AGREEMENT




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TABLE OF CONTENTS
 PageARTICLE I. DEFINITIONS
    
    
    1Section 1.01. Definitions
    
    
    1ARTICLE II. CONSIDERATION
    
    
    2Section 2.01. Sale and Delivery of Purchased Assets
    
    
    2Section 2.02. Excluded Assets
    
    
    3Section 2.03. Liabilities
    
    
    3Section 2.04. Further Assurances
    
    
    4Section 2.05. Purchase Price
    
    
    4Section 2.06. Allocation of Purchase Price
    
    
    5Section 2.07. Stock Matters
    
    
    5ARTICLE III. CLOSING
    
    
    5Section 3.01. Closing
    
    
    5Section 3.02. Closing Deliveries
    
    
    6ARTICLE IV. REPRESENTATIONS AND WARRANTIES OF THE SELLER
    
    
    7Section 4.01. Organization and Good Standing
    
    
    7Section 4.02. Execution and Effect of Agreement
    
    
    8Section 4.03. Permits; Compliance with Law
    
    
    8Section 4.04. Lease of Real Property
    
    
    8Section 4.05. Assumed Contracts
    
    
    9Section 4.06. Personal Property
    
    
    9Section 4.07. No Conflicts
    
    
    9Section 4.08. Litigation
    
    
    10Section 4.09. Consents
    
    
    10Section 4.10. Environmental Matters
    
    
    10Section 4.11. Supplier Relationships
    
    
    10ARTICLE V. REPRESENTATIONS AND WARRANTIES OF THE BUYER
    
    
    11Section 5.01. Organization and Good Standing
    
    
    11Section 5.02. Execution and Effect of Agreement
    
    
    11Section 5.03. No Violation
    
    
    11Section 5.04. Consents
    
    
    11ARTICLE VI. PRE-CLOSING COVENANTS
    
    
    12Section 6.01. HSR Filing and Other Actions
    
    
    12Section 6.02. Continuing Access
    
    
    12Section 6.03. Cooperation
    
    
    13Section 6.04. Conduct of Business Pending Closing
    
    
    13Section 6.05. No Shop
    
    
    14Section 6.06. Notification of Certain Matters
    
    
    14Section 6.07. Public Announcements
    
    
    15Section 6.08. Operating Expenses
    
    
    15Section 6.09. Transaction Expenses
    
    
    15
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PageSection 6.10. Further Assurances
    
    
    15ARTICLE VII. POST-CLOSING COVENANTS
    
    
    16Section 7.01. Payment of Taxes
    
    
    16Section 7.02. Mutual Non-Solicitation; Non-Hire
    
    
    16Section 7.03. Access to Records
    
    
    16Section 7.04. Qualified Financing Documents
    
    
    17Section 7.05. Employees of the CoGenesys Business
    
    
    17ARTICLE VIII. CONDITIONS PRECEDENT TO THE OBLIGATIONS OF THE SELLER
    
    
    17Section 8.01. Representations and Warranties
    
    
    17Section 8.02. Performance of Obligations
    
    
    17Section 8.03. No Litigation
    
    
    17Section 8.04. Consents and Approvals
    
    
    18Section 8.05. Qualified Financing
    
    
    18ARTICLE IX. CONDITIONS PRECEDENT TO THE OBLIGATIONS OF THE BUYER
    
    
    18Section 9.01. Representations and Warranties
    
    
    18Section 9.02. Performance of Obligations
    
    
    18Section 9.03. No Litigation
    
    
    18Section 9.04. No Material Adverse Effect
    
    
    18Section 9.05. Consents and Approvals
    
    
    19Section 9.06. Qualified Financing
    
    
    19ARTICLE X. INDEMNIFICATION
    
    
    19Section 10.01. Obligations of the Seller
    
    
    19Section 10.02. Obligations of the Buyer
    
    
    19Section 10.03. Tax Indemnification
    
    
    20Section 10.04. Procedure
    
    
    20Section 10.05. Survival
    
    
    21Section 10.06. Limitations
    
    
    21Section 10.07. Remedies
    
    
    22ARTICLE XI. TERMINATION
    
    
    22Section 11.01. Termination
    
    
    22Section 11.02. Consequences of Termination
    
    
    23ARTICLE XII. GENERAL PROVISIONS
    
    
    23Section 12.01. Cooperation
    
    
    23Section 12.02. Confidentiality
    
    
    24Section 12.03. Amendments and Waivers
    
    
    26Section 12.04. Successors and Assigns
    
    
    26Section 12.05. No Third Party Beneficiaries
    
    
    27Section 12.06. Choice of Law
    
    
    27Section 12.07. Waiver of Jury Trial
    
    
    27Section 12.08. Notices
    
    
    27Section 12.09. Waiver of Bulk Sales
    
    
    28Section 12.10. Severability
    
    
    28Section 12.11. Entire Agreement
    
    
    28Section 12.12. Construction
    
    
    28
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PageSection 12.13. Titles and Subtitles
    
    
    29Section 12.14. Time
    
    
    29Section 12.15. Counterparts
    
    
    29
 EXHIBITS
    
    PageExhibit A  Definitions
    
    
    A-1Exhibit B  Allocation of Purchase Price
    
    
    B-1Exhibit C  Term Sheet
    
    
    C-1Exhibit D  License Agreement
    
    
    F-1Exhibit E  Services Agreement
    
    
    D-1Exhibit F  Manufacturing Services Agreement
    
    
    E-1Exhibit G  Lease Assignment Agreement
    
    
    G-1Exhibit H  Form of Bill of Sale
    
    
    H-1Exhibit I  Form of Assignment and Assumption Agreement
    
    
    I-1Schedules
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ASSET PURCHASE AGREEMENT
 THIS ASSET PURCHASE AGREEMENT
 R E C I T A L S
     ARTICLE I.
DEFINITIONS
 Section 1.01. Definitions .
 Exhibit A Exhibit A
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ARTICLE II.
CONSIDERATION
 Section 2.01. Sale and Delivery of Purchased Assets .
  Assumed Contracts and Certain Other Rights of the Seller Schedule 2.01(a)
 Equipment Schedule
2.01(b) Schedule
2.01(b)
 Inventory. Schedule 2.01(c)
 Name
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Records
 Permits Schedule 4.05
 Goodwill
  Section 2.02. Excluded Assets .
 Section 2.01
 Records
 Licensed Technology
 Sellers Other Business
 Section 2.03. Liabilities .
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Section 2.04. Further Assurances .
  Section 2.05. Purchase Price .
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Section 2.06. Allocation of Purchase Price .
 Exhibit B Exhibit B
 Section 2.07. Stock Matters .
  Exhibit C
 ARTICLE III.
CLOSING
 Section 3.01. Closing .
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Section 3.02. Closing Deliveries .
   Exhibit D
 Exhibit E
 Exhibit F
 Exhibit G
 Exhibit H
 Exhibit I
   Sections 9.01 9.02
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Section 2.05
     Section 2.05
    Sections 8.01 8.02
  ARTICLE IV.
REPRESENTATIONS AND WARRANTIES OF THE SELLER
 Article IV
 Section 4.01. Organization and Good Standing .
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Section 4.02. Execution and Effect of Agreement .
  Section 4.03. Permits; Compliance with Law .
  Schedule 4.03 Schedule 4.03 Schedule 4.03 Schedule 4.03 Schedule 4.03
 Section 4.04. Lease of Real Property .
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Schedule 4.04(b)
  Section 4.05. Assumed Contracts .
  Section 4.06. Personal Property .
 Schedule 4.06 Schedule 4.06 Schedule 4.06 Schedule 4.06 Schedule 4.06
 Section 4.07. No Conflicts .
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Section 4.08. Litigation .
  Section 4.09. Consents .
 Schedule
4.09
 Section 4.10. Environmental Matters .
 Schedule 4.10
 Section 4.11. Supplier Relationships .
 Schedule 4.11
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Schedule 4.11
 ARTICLE V.
REPRESENTATIONS AND WARRANTIES OF THE BUYER
  Section 5.01. Organization and Good Standing .
  Section 5.02. Execution and Effect of Agreement .
  Section 5.03. No Violation .
  Section 5.04. Consents .
 Schedule
5.04
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ARTICLE VI.
PRE-CLOSING COVENANTS
 Section 6.01. HSR Filing and Other Actions .
   Section 6.02. Continuing Access .
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Section 6.03. Cooperation .
  Section 6.04. Conduct of Business Pending Closing .
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Article IV
   Section 6.05. No Shop .
  Section 6.06. Notification of Certain Matters .
 Section 6.06 Articles
VIII IX
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Article XI
 Section 6.07. Public Announcements .
  Section 6.08. Operating Expenses .
  Section 6.09. Transaction Expenses .
 Sections 10.01 and 10.02
 Section 6.10. Further Assurances .
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ARTICLE VII.
POST-CLOSING COVENANTS
 Section 7.01. Payment of Taxes .
  Section 7.02. Mutual Non-Solicitation; Non-Hire .
  Non-Hire
 Non-Solicitation
 Section 7.03. Access to Records .
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Section 7.04. Qualified Financing Documents .
  Section 7.05. Employees of the CoGenesys Business .
 Schedule 7.05
 ARTICLE VIII.
CONDITIONS PRECEDENT TO THE OBLIGATIONS OF THE SELLER
 Article VIII
 Section 8.01. Representations and Warranties .
  Section 8.02. Performance of Obligations .
  Section 8.03. No Litigation .
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Section 8.04. Consents and Approvals .
  Section 8.05. Qualified Financing .
  ARTICLE IX.
CONDITIONS PRECEDENT TO THE OBLIGATIONS OF THE BUYER
 Article IX
 Section 9.01. Representations and Warranties .
  Section 9.02. Performance of Obligations .
  Section 9.03. No Litigation .
  Section 9.04. No Material Adverse Effect .
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Section 9.05. Consents and Approvals .
 Schedule 4.11
 Section 9.06. Qualified Financing .
  ARTICLE X.
INDEMNIFICATION
 Section 10.01. Obligations of the Seller .
 Section 10.06
 Section 10.02. Obligations of the Buyer .
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Section 10.03. Tax Indemnification .
 ad valorem
 Section 10.04. Procedure .
 Section 10.05
 Article X
 unless
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provided however
 Section 10.05. Survival .
 Article X
 Section 10.06. Limitations .
 Section 10.01 Article X
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Section 10.01
 Section 10.07. Remedies .
 Section 10.07
  ARTICLE XI.
TERMINATION
 Section 11.01. Termination .
   Section
11.01(b)
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Section 11.02. Consequences of Termination .
 Article XI provided however Section 12.02
 ARTICLE XII.
GENERAL PROVISIONS
 Section 12.01. Cooperation .
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Section 12.02. Confidentiality .
    except unless
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unless
  Section 12.02
  Section 12.02 provided, however
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provided, however
 Section 12.03. Amendments and Waivers .
  Section 12.04. Successors and Assigns .
 provided however except
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Section 12.05. No Third Party Beneficiaries .
 provided however Article X
 Section 12.06. Choice of Law .
    Section 12.07. Waiver of Jury Trial .
  Section 12.08. Notices .
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Section 12.08
 If to the Buyer, to:
    
    With a copy to:TriGenesys, Inc.
22400 Rolling Hill Lane 
Laytonsonville, Maryland 20852
    
    Cooley Godward LLP
11951 Freedom Drive
Reston, Virginia 20190Fax: 703-456-8100Attn: Craig A. Rosen, Ph.D.
    
    Attn: Michael R. LincolnIf to the Seller, to:
    
    With a copy to:Human Genome Sciences, Inc.
14200 Shady Grove Road
Rockville, Maryland 20850
Fax: (301) 309-8512
Attn: James H. Davis, Ph.D., Esq.
    
    DLA Piper Rudnick Gray Cary US LLP
6225 Smith Avenue
Baltimore, Maryland 21209
Fax: (410) 580-3170
Attn: Robert W. Smith, Jr., Esq.
 Section 12.09. Waiver of Bulk Sales .
  Section 12.10. Severability .
  Section 12.11. Entire Agreement .
  Section 12.12. Construction .
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Section 12.13. Titles and Subtitles .
  Section 12.14. Time .
  Section 12.15. Counterparts .
  [Signatures appear on the following pages]
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IN WITNESS WHEREOF
 BUYER
    
    TRIGENESYS, INC.By:
    
    /s/ Craig A. Rosen, Ph.D.Name:
    
    Craig A. Rosen, Ph.D.Title:
    
    Chairman of the Board of DirectorsSELLER
    
    HUMAN GENOME SCIENCES, INC.By:
    
    /s/ H. Thomas WatkinsName:
    
    H. Thomas WatkinsTitle:
    
    Chief Executive Officer
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EXHIBIT A
 DEFINITIONS
 Action Section 10.04
 Affiliate
 Agreement
 Assignment and Assumption Agreement Section 3.02
 Assumed Contracts Section 2.01
 Assumed Liabilities Section 2.03
 Bill of Sale Section 3.02
 Business
 Business Day
 Buyer
 Buyer Indemnified Person Section 10.01
 Buyers Equity Section 2.05
 Buyers Knowledge
 CERCLA
 Closing Section 3.01
 Closing Date Section 3.01




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Enforceability Exceptions Section 4.02
 Environmental Laws
 Equipment Section 2.01
 ERISA
 Excluded Assets Section 2.02
 Excluded Liabilities Section 2.03
 Excluded Records Section 2.02
 Governmental Authority
 Hazardous Materials
 HSR Act
 Indemnified Person Section 10.04
 Indemnifying Person Section 10.04
 Inventory Section 2.01




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Lease Section 3.02
 Lease Assignment Agreement Section 3.02
 Liability
 Lien provided however
 License Agreement Section 3.02
 Material Adverse Effect
 Manufacturing Services Agreement Section 3.02
 Name Section 2.01
 Operating Expenses Section 6.08
 Order
 Permits
 Permitted Lien




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Schedule 4.08
 Person
 Proceeding
 Purchased Assets Section 2.01
 Purchase Price Section 2.05
 Qualified Financing Section 2.05
 Qualified Financing Documentation Section 2.07
 Records Section 2.01
 Representative
 Securities Act Section 2.07
 Seller
 Seller Indemnified Person Section 10.02
 Sellers Knowledge
 Services Agreement Section 3.02
 Site Section 4.14




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Tax Taxes ad valorem
 Tax Code