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                                                                   Exhibit 10.21
                                    FORM OF
                    SCIENTIFIC ADVISORY BOARD AND CONSULTANT
                                   AGREEMENT


This Scientific Advisory Board and Consultant Agreement (this "Agreement") is
entered into effective as of __________, 2000, by and between Keryx
Biopharmaceuticals, Inc., a Delaware corporation, with a mailing address at 216
Jaffa Road, Jerusalem 94383 Israel ("the Corporation") and Moshe Oren, Ph.D.,
with a mailing address of ____________________________________________________
(the "Advisor").

1.   Services of the Advisor.
     -----------------------

     (a)  The Advisor agrees to perform scientific advisory services for the
     Corporation as a member of its Scientific Advisory Board and shall provide
     consultant services, devoting such time, attention, knowledge and skill as
     reasonably requested by the Corporation's Board of Directors or their
     designee, and as the interests, needs, business or opportunities of the
     Corporation shall require, at such time and place as the Corporation's
     Board of Directors or their designee shall reasonably request (the
     "Services"), for a period of three (3) years, unless earlier terminated in
     accordance with Section 3  (the "Services Period").  The Services Period
     may be extended for additional one (1) year periods upon the written
     agreement of the parties hereto.

     (b)  The Corporation acknowledges that the Advisor is an employee of the
     Weizmann Institute (the "Institute") and is subject to the Institute's
     policies, including policies concerning consulting, conflicts of interest,
     and intellectual property.

     (c)  The scope of the Advisor's work as a consultant of the Corporation
     shall be the modulation of protein kinase activity by short peptides or
     derivatives thereof (the "Project"). To the best of the parties' knowledge,
     the Project does not overlap or conflict with any work the Advisor is doing
     at the Institute.

2.   Compensation for Service Rendered.
     ---------------------------------

     (a) Monthly Consulting Fee. The Corporation shall pay the Advisor in his
     capacity as a consultant to the Corporation at a rate of two thousand
     dollars ($2,000) per month, payable monthly in arrears upon presentation of
     an invoice.

     (b) Stock Options. Within twenty one (21) days of the execution of this
     Agreement by the Advisor, the Board of Directors of the Corporation or a
     duly formed committee thereof shall issue to the Advisor an option to
     purchase one thousand (1,000) shares of the Corporation's Common Stock at a
     price equal to offering price at the initial public offering of the
     Corporation's Common Stock. Of these, five hundred (500) shall be deemed
     vested as of the date of grant and the balance shall vest in two equal
     annual installments, with the first occurring on the first anniversary of
     the date of the grant, provided that on the each vesting date the Advisor
     is still being retained pursuant to this or a similar agreement with the
     Corporation. Such options shall be deemed to have been granted pursuant to,
     and

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     shall be governed by, the Corporation's stock option program applicable
     to consultants to the Corporation. If this Agreement is terminated by the
     Corporation or the Advisor for any reason prior to the expiration of its
     term, the Corporation shall have the right to repurchase the vested portion
     of such options (or the shares resulting from the exercise of such options
     if such exercise has occurred) at the then-current fair market value of
     such shares or options, as reasonably determined by the Board of Directors
     of the Corporation. Such right shall be exercised by the Corporation and
     payment made, if at all, within ninety (90) days after the effective date
     of such termination.

3.   Termination.  The obligation of the Advisor to perform the Services may be
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     terminated by the Corporation during the Services Period with respect to
     the Advisor for any reason, with or without cause, upon the agreement of a
     majority of the Corporation's Board of Directors.

     The Advisor may voluntarily terminate his obligation to perform the
     Services for the Corporation at any time and for any reason (a "Voluntary
     Termination"). However, the Advisor agrees to provide thirty (30) days
     advance notice prior to the effective date of termination.

4.   Agreement Not to Compete.  During the Services Period and for twelve (12)
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     months thereafter, the Advisor agrees that he will not affiliate in any
     material role, including affiliation as an employee, consultant agent, or
     contractor, with any business enterprise which is in direct conflict or
     competition with the Corporation in the modulation of protein kinases to
     discover or develop pharmaceutical products (the "Field") nor will he
     found, promote or become a shareholder, partner, or owner in any other
     enterprise which competes with the Corporation in the Field other than as
     stockholder of up to five percent (5%) of the outstanding stock of any
     publicly traded corporation. Notwithstanding the foregoing, nothing in this
     Section shall prevent or inhibit the Advisor from conducting academic
     research in subjects related to the Field provided that the Advisor
     complies with the confidentiality obligations set forth in Section 7,
     below. In addition, the Corporation acknowledges and agrees that the
     Advisor's activities in connection with his employment by the Institute
     shall not be considered competitive and nothing in this Agreement shall
     affect the Advisor's obligations to, or research on behalf of, the
     Institute, including, without limitation, obligations or research of the
     Advisor in connection with a transfer by the Institute of materials or
     intellectual property developed in whole or in part by the Advisor, or in
     connection with research collaborations.

5.   Noninterference With Employees.  The Advisor agrees that for a period of
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     twelve (12) months following the termination of the performance of the
     Services for the Corporation by the Advisor, the Advisor will not interfere
     with or attempt to impair the relationship between the Corporation and any
     of its employees, consultants, and advisors, nor will the Advisor attempt
     to solicit, to entice, to hire, or otherwise to induce any employee,
     consultant, or advisor of the Corporation to terminate association with the
     Corporation.

6.   Remedies in the Event of Breach. The Corporation and the Advisor understand
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     and agree that any breach or threatened breach by the Corporation or the
     Advisor

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     of any of the provisions set forth in Section 4 and 5, cannot be remedied
     solely by the recovery of damages, and in the event of any such breach or
     threatened breach, the Corporation and the Advisor, as the case may be,
     shall be entitled to seek injunctive relief, restraining the Advisor or the
     Corporation, as the case may be, and any business, firm, corporation,
     individual, or other entity participating in such breach or attempted
     breach from engaging in any activity which would constitute a breach. The
     Corporation and the Advisor further agree that any dispute arising under
     the terms of this Agreement, other than a dispute that would be remedied by
     injunctive relief, shall be decided in accordance with the then current
     rules of the American Arbitration Association, and any arbitration award
     may be entered in a court of competent jurisdiction and enforced as a
     judgment thereof. Any such arbitration shall be heard at an appropriate
     location in the City of New York. Nothing herein, however, shall be
     construed as prohibiting the Corporation or the Advisor from pursuing, in
     conjunction with an injunction or otherwise, any other remedies available
     in equity for any such breach or threatened breach, including the recovery
     of damages.

7.   Non-Disclosure and Developments.
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  (a) Advisor shall not at any time, whether during or after the termination
     of this Agreement, disclose to any person or entity any of the trade
     secrets or confidential information concerning the organization, business
     or finances of the Corporation or of any third party which the Corporation
     is under an obligation to keep confidential (including but not limited to
     trade secrets or confidential information respecting inventions, patent
     applications, products, designs, methods, know-how, techniques systems,
     processes, software programs, works of authorship customer lists, projects,
     plans and proposals), except as may be required in the ordinary course of
     performing the Advisor's duties on behalf of the Corporation, and the
     Advisor shall keep secret all matters entrusted to the Advisor and shall
     not use or attempt to use any such information in any manner which may
     injure or cause loss or may be calculated to injure or cause loss whether
     directly to the Corporation.

     Further, the Advisor agrees that during the term of this Agreement, the
     Advisor shall not make, use or permit to be used any notes, memoranda,
     reports, lists, records, drawings, sketches, specifications, software
     programs, data, documentation, or other materials of any nature arising out
     of, or in connection with, this Agreement otherwise than for the benefit of
     the Corporation. The Advisor further agrees that he shall not, after the
     termination of this Agreement, use or permit to be used any such notes,
     memoranda, reports, lists, records, drawings, sketches, specifications,
     software programs, data, documentation or other materials, it is agreed
     that all of the foregoing shall be and remain the sole and exclusive
     property of the Corporation and that immediately upon the termination of
     this Agreement, the Advisor shall deliver all of the foregoing, and all
     copies thereof in his possession or under his control,  to the Corporation,
     at its main office.

     Notwithstanding the foregoing, the Advisor may disclose information (i)
     received from a third party (other than the Corporation) which is not
     subject to any confidentiality restriction, (ii) required by law to be
     disclosed, including,

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     by way of example and not limitation, pursuant to a subpoena or other
     discovery device or a court order, or (iii) already in the public domain.

  (b)  All products, concepts, ideas and other work product of the Advisor
     relating to the Project and resulting from the Services the Advisor
     provides to the Corporation pursuant to this Agreement (herein called
     "Developments") , whether patentable or not, shall be deemed to be the
     exclusive property of the Corporation. The Advisor shall promptly disclose
     to the Corporation (or any persons designated by it) each such Development.
     The Advisor hereby unconditionally assigns any rights (including, but not
     limited to, any copyrights and trademarks) the Advisor may have or acquire
     in the Developments and benefits and/or rights resulting therefrom to the
     Corporation and its assigns without further compensation, as may be
     necessary to ensure the Corporation's ownership of such Developments, and
     shall communicate, without cost or delay, and without disclosing to others
     the same, all available information relating thereto (with all necessary
     plans and models) to the Corporation.

     The Advisor shall during this Agreement, and at any time thereafter, at the
     request and cost of the Corporation, promptly sign, execute make and do all
     such deeds, documents, acts and things as the Corporation and its duly
     authorized agents may reasonably require (iv) to apply for, obtain register
     and vest in the name of the Corporation alone (unless the Corporation
     otherwise directs) letters patents, copyrights, trademarks or other
     analogous protection relating to the Developments in any country throughout
     the world and when so obtained or vested to renew and restore the same; and
     (v) to defend any judicial opposition or  other proceedings in respect of
     such applications and any judicial, opposition or other proceedings or
     applications for revocation of such letters patent, copyright, trademark or
     other analogous protection.

     In the event the Corporation is unable, after reasonable effort, to secure
     the Advisor's signature on any application for letters patent, copyright or
     trademark registration or other documents regarding any legal protection
     relating to the Developments, whether because of the Advisor's physical or
     mental incapacity or for any other reason whatsoever, the Advisor hereby
     irrevocably designated and appoints the Corporation and its duly authorized
     officers and agents as his agent and attorney-in-fact, to act for and in
     the Advisor's behalf and stead to execute and file any such application or
     applications or other documents and to do all other lawfully permitted acts
     to further the prosecution and issuance of letters patent, copyright or
     trademarks registrations, or any other legal protection thereon with the
     same legal force and effect as if executed by the Advisor.

     It is understood that any intellectual property or Developments which the
     Advisor has developed, or in the future may develop, which is or will be,
     owned or licensed by his current employer or any other permitted employer
     of his (other than the Corporation) shall not be subject to this Agreement.
     It is further understood that in the event that there is reasonable
     uncertainty whether certain information which Advisor has obtained is
     required to be disclosed to the Corporation pursuant to this Subsection
     (b), Advisor

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     shall have a reasonable amount of time to consult with his current employer
     or any other permitted employer of Advisor to whom such information may
     belong before determining whether or not to disclose such information to
     the Corporation.

  (c)  Advisor agrees that any breach of this Agreement by Advisor will cause
     irreparable damage to the Corporation and that in the event of such breach
     the Corporation shall have, in addition to any and all remedies of law, the
     right to seek an injunction, specific performance or other equitable relief
     to prevent the violation of the Advisor's obligations hereunder.

  (d)  The Advisor further represents that his performance of all of the terms
     of this Agreement does not and will not breach any agreement to keep in
     confidence proprietary information acquired by him in confidence or in
     trust prior to his obligation to perform Services for the Corporation. The
     Advisor has not entered into, and agrees that he shall not enter into, any
     agreement either written or oral in conflict herewith.

8.  Independent Contractor.
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 (a) The Advisor agrees that in rendering the Services hereunder, the Advisor
     and any person employed by, or subcontracting with, the Advisor to perform
     the Services, shall act (and be considered for all purposes) as an
     independent contractor of the Corporation, and not as an employee or agent
     of the Corporation. In his capacity as an independent contractor, the
     Advisor agrees and represents, and the Corporation agrees, that the
     Advisor: (i) has the right to control and direct the means and methods of
     performing the Services by himself, his employees, and his subcontractors;
     (ii) will provide supervision of all his employees and subcontractors
     assigned to perform the Services; (iii) will utilize and pay for the
     Advisor's, and his employees' and subcontractors' own tools and equipment,
     and will reimburse the Corporation for the use of the Corporation's
     equipment and administrative services, facilities and other consideration
     provided by the Corporation; (iv) shall receive compensation from the
     Corporation only as set forth herein and will not participate in benefits
     of any sort which the Corporation offers to its subcontractors; (v) shall,
     to the extent practical, keep his equipment, materials, drawings, and the
     like separate from any Corporation property, and will not remove any
     Corporation property from the premises without prior written approval by an
     authorized representative of the Corporation; (vi) maintain a place of
     business at a location other than the premises of the Corporation; (vii)
     will not require that he, his employees, or his subcontractors be trained
     by the Corporation in the professional skills necessary to perform the
     Services, though the Corporation may give general directions and
     orientation instructions; (viii) shall be fully liable for the grossly
     negligent or willful injurious acts or omissions of himself, his employees,
     or his subcontractors, causing harm to persons or property, but shall not
     be liable for consequential damages due to defects in performance; and (ix)
     shall deal with the Advisor's employees' or subcontractors' trade or union
     representatives, negotiate all employee and subcontractor disputes and
     terminate or change all employee or subcontractor assignments as necessary.

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   (b) Inasmuch as the Advisor and the Corporation are contractors independent
       of one another, neither has the authority to bind the other to any third
       person or otherwise to act in any way as the representative of the other,
       unless otherwise expressly agreed to in writing signed by both parties
       hereto. The Advisor agrees not to represent himself as the Corporation's
       agent for any purpose to any party unless specifically authorized, in
       advance and in writing, to do so, and then only for the limited
       purposes(s) stated in such authorization. This prohibition includes the
       use by the Advisor of the Corporation's stationery and forms; all
       contracts with third parties shall be made on the Advisor's own
       stationery and in the Advisor's own name, as appropriate. The Advisor
       agrees to assume full liability for any contracts or agreements the
       Advisor, his employees, or his subcontractors, if any, enter into on
       behalf of the Corporation without the express knowledge and written
       consent of the Corporation.

  (c)  The Corporation shall indemnify and hold blameless the Advisor against
       any claims, losses, expenses, costs, obligations, and liabilities arising
       out of, or in connection with, the performance of the Services by the
       Advisor, except for (i) such claims, losses expenses, costs, obligations,
       and liabilities as arise out of the gross negligence or willful injurious
       acts or omissions of the Advisor and (ii) such claims, losses, expenses,
       costs, obligations, and liabilities as the Advisor may be answerable to
       the Corporation for.

9.   Taxes.  The Advisor shall be responsible for the withholding, and payment,
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     as required by law, of all federal, state, and local taxes imposed on the
     Advisor because of the performance of the Services hereunder. Further, the
     Advisor shall comply with all federal, state, and local benefits laws
     applicable to the Advisor, including making deductions and contributions
     for social security and unemployment taxes. Each party to this Agreement
     shall otherwise be responsible for the payment of any other taxes imposed
     upon it or him in connection with, or as a result of, this Agreement.

10.  Site of Services.  The Advisor will perform the Services at a location
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     other than the premises of the Corporation if possible, or if the Services
     are such that the Services must be performed on the Corporation's premises,
     the Corporation shall provide the Advisor with office space and facilities
     commensurate with that provided to its own employees to the extent
     necessary to perform the Services specified by this Agreement. The Advisor
     will restrict the performance of the Services to a separate assigned work
     area as much as is feasible.

11.  Travel Expenses.  The Corporation will reimburse the Advisor for all
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     reasonable travel expenses, approved in advance by the Corporation, upon
     receipt of supporting documentation.

12.  Inventions.  The Corporation shall compensate the Advisor on a case-by-case
     ----------
     basis for any third party inventions licensed, assigned, or otherwise
     acquired by the Corporation through the efforts of the Advisor or conceived
     and reduced to practice by the Advisor and not otherwise the property of
     the Corporation in whole or in part.

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13.  Non-Exclusive Right.  The Corporation may contract with individuals other
     -------------------
     than the Advisor for the Services. The Advisor does not have an exclusive
     right to provide the Services to the Corporation.

14.  Waiver.   Any waiver by the Corporation of a breach of any provision of
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     this Agreement shall not operate or be construed as a waiver of any
     subsequent breach of such provision or any other provision hereof.

15.  Severability.  If for any reason any clause or provision of this Agreement,
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     or the application of any such clause or provision in a particular context
     or to a particular situation, circumstance or person, should be held
     unenforceable, invalid or in violation of law by any court or other
     tribunal, then the application of such clause or provision in contexts or
     to situations, circumstances or persons other than that in or to which it
     is held unenforceable, invalid or in violation of law shall not be affected
     thereby, and the remaining clauses and provisions hereof shall,
     nevertheless, remain in full force and effect.

16.  Governing Law.   This Agreement shall be governed by, and construed in
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     accordance with, the laws of the State of New York.

     IN WITNESS WHEREOF, the Corporation has caused this Agreement to be
     executed, and the Advisor has executed this Agreement, as of the date first
     set forth above.



     KERYX BIOPHARMACEUTICALS, INC.  ADVISOR



     By:__________________________         By:_________________________


     Name: _______________________


     Title: ______________________

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