<PAGE>   1
                                                                   EXHIBIT 10.22


                             AMENDMENT NUMBER ONE TO
                              INVESTORS' AGREEMENT

         THIS AMENDMENT NUMBER ONE TO INVESTORS' AGREEMENT dated as of July __,
2000, by and among the individuals set forth on Exhibit A attached hereto
(individually and collectively referred to as "Sellers"), SynQuest, Inc., a
corporation formed under the laws of the State of Georgia and successor to
Factory Automation & Computer Technologies, Inc., a corporation formed under the
laws of the State of New York ("Buyer"), and Warburg, Pincus Investors, L.P., a
Delaware limited partnership ("Warburg"), which amends that certain Investors'
Agreement dated as of February 23, 1996 (the "Original Agreement").

                              W I T N E S S E T H:

         WHEREAS, in consideration of cash and an aggregate of 622,005 shares of
Buyer's common stock, par value $0.01 per share ("Common Stock"), Buyer acquired
all of the issued and outstanding shares of Log'In, a societe anonyme formed
under the laws of France, from ABR Europe S.A., A.D.I. S.A., corporations formed
under the laws of France (collectively, the "Dissolved Owners"), and the
Original Sellers (as identified on Exhibit A attached hereto), pursuant to that
certain Stock Purchase Agreement dated February 23, 1996 (the "Stock Purchase
Agreement");

         WHEREAS, contemporaneously with the execution and delivery of the Stock
Purchase Agreement, Buyer, Warburg, the Dissolved Owners and the Original
Sellers entered into the Original Agreement;

         WHEREAS, subsequent to the execution of the Original Agreement, each of
the Distributee Sellers (as identified on Exhibit A attached hereto) acquired
from the Dissolved Owners or their beneficial owners, in one or more
transactions or series of related transactions, such number of shares of Common
Stock as is set forth opposite his or her name on Exhibit A attached hereto;

         WHEREAS, the Dissolved Owners no longer own, beneficially or of record,
any shares of Common Stock;

         WHEREAS, each of the Sellers owns beneficially and of record such
number of shares of Common Stock as is set forth opposite his or her name on
Exhibit A attached hereto; and

         WHEREAS, Sellers, Buyer and Warburg desire to amend the Original
Agreement as more fully set forth herein.

         NOW, THEREFORE, in consideration of the premises and the mutual
promises contained herein, and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, Sellers, Buyer and
Warburg do hereby agree to amend the Original Agreement as follows:


<PAGE>   2

There shall be added to the Original Agreement a new Article VI which shall read
as follows:

                     "ARTICLE VI.         TERMINATION.

                     This Agreement shall terminate upon the closing of an
                     initial public offering of Buyer's common stock, par value
                     $.01 per share."

         Except as amended herein, the provisions of the Original Agreement
shall remain in full force and effect.


                                        2
<PAGE>   3

         IN WITNESS WHEREOF, each of Sellers, Buyer and Warburg has caused its
duly authorized representative to execute this Amendment Number One to
Investors' Agreement on its behalf as of the date first above written.

                                    BUYER:

                                    SYNQUEST, INC.

                                    By:
                                       -----------------------------------------
                                       Name:
                                            ------------------------------------
                                       Title:
                                             -----------------------------------


                                    ORIGINAL SELLERS:

                                    By:
                                       -----------------------------------------
                                       Laurent Martineau

                                    By:
                                       -----------------------------------------
                                       Claude Martineau

                                    By:
                                       -----------------------------------------
                                       Pierre-Andre Dubreuil

                                    By:
                                       -----------------------------------------
                                       Seaforth Lyle

                                    By:
                                       -----------------------------------------
                                       Bertrand Renaud


                                    DISTRIBUTEE SELLERS

                                    By:
                                       -----------------------------------------
                                       Alain Renaud

                                    By:
                                       -----------------------------------------
                                       Arthur Litrowski

                                    By:
                                       -----------------------------------------
                                       Richard Litrowski

                                    By:
                                       -----------------------------------------
                                       Catherine Wajsmann


                                        3
<PAGE>   4

                                    By:
                                       -----------------------------------------
                                       Serge Lancrey-Javal

                                    By:
                                       -----------------------------------------
                                       Laurent Lancrey-Javal

                                    By:
                                       -----------------------------------------
                                       Katherine Litrowski

                                    By:
                                       -----------------------------------------
                                       Beatrice Litrowski

                                    By:
                                       -----------------------------------------
                                       Michel Bertoni


                                    WARBURG:

                                    WARBURG, PINCUS INVESTORS, L.P.

                                    By:
                                       -----------------------------------------
                                       Name:
                                            ------------------------------------
                                       Title:
                                             -----------------------------------


                                        4
<PAGE>   5

                                    EXHIBIT A

                                     SELLERS


<TABLE>
<CAPTION>

                                                               NUMBER OF
         ORIGINAL SELLERS                                        SHARES
         ----------------                                      ---------
         <S>                                                   <C>
         Laurent Martineau....................................  239,290
         Claude Martineau.....................................   16,099
         Pierre-Andre Dubreuil................................   19,832
         Seaforth Lyle........................................   56,346
         Bertrand Renaud......................................   11,709

         DISTRIBUTEE SELLERS
         Alain Renaud.........................................   43,174
         Arthur Litrowski.....................................  178,028
         Richard Litrowski....................................   28,656
         Catherine Wajsmann...................................   17,199
         Serge Lancrey-Javal..................................   11,458
         Laurent Lancrey-Javal................................       73
         Katherine Litrowski..................................       68
         Beatrice Litrowski...................................       68
         Michel Bertoni.......................................        5
</TABLE>