### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C

. 20460

OFFICE OF CHEMICAL SAFETY AND POLLUTION P R EVENTION



### MEM O RANDUM

Date:

Subject:

PC Code: Decision Nos.: Petition Nos.: 

### 22-July-2015



### Fl u dioxo n il. Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessment for Uses on Carrot, Stone Fruit

, Group 12-12, and Rapeseed

, Subgroup 20A.

071503 491305,491195 4E8272 (Carrot) 4F8277 (Rapeseed) DP Barcode: Registrat i on Nos. Reg ul atory Action: 0426862
I 00-1242

, I 00- 758 NA

Risk Assessment Type: NA Case No.: 7017 131341-86

- 1 §180

. 516 TXR No.: NA CAS No.:
MRIDNo.:



### From:

Through:

To: None 40 CF R :



### William D. Wassell, Chemist 

# li'f,,j/tl,**l}JfJ~ /7/**  Risk Assessment Branch 1 (RAB 1)

## ~ Health Effects Division (HED, 7509P)

Kristin Rury, DESAC Reviewer 

# ;J/ I/_ 

# h..:. 

# V

Sheila Piper

, DESAC

# Reviewer**S~~p-..'.-­** Dietary Exposure Science Advisory Council (DESAC)

## ~d**~** George F

. Kramer, Ph.D., Branch Senior Chern y

## ~ -- RAB 1/HED (7509P)

William D

. Wassell, Risk Assessor RAB 1/HED (7509C) And Barbara Madden/ A. Willis Ertman, RM 05 Registration Division (7505P)



### Executive S u m m ary

Dietar y (food plus water) exposure and risk assessments were conducted using Dietary Exposure E v aluation Model

- Food Consumption Intake Database (DEEM-FCID)

, ver. 3

. 16, which uses food consumption data from the U.S. Department of Agriculture's (USDA ' s) National Health and Nutrition Examination Survey, What We Eat in America

, (NHANES/WWEIA). This dietary survey

was conducted from 2003 to 2008. These**~alyses** 

### were performed to support the proposed Section 3 uses of fludioxonil on carrot and rapeseed

, subgroup 20A. Additionally

, the fludioxonil**toler~ce**

Page I of 17Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 2 of 17 

### and use for stone fruit, group 12 is being extended to the redefined stone fruit, group 12-12. This memorandum was reviewed by two peer reviewers as per DESAC Standard Operating Procedures.

Acute Dietary (Food and Drinking Water) Ex posure Results and Characterization

An acute dietary exposure assessment was not performed as there were no appropriate toxicological effects attributable to a single exposure (dose) observ ed in available oral toxicity studies, including maternal toxicity in the develo pmental toxicity studies. Therefore, a dose and endpoint were not identified for this risk assessment.

Chronic Dietary (Food and Dr inking Water) Exposure Resu lts and Characterization

An unrefined chronic dietary exposure and riskassessment was performed assuming tolerancelevel residues, 100% crop treated (CT) estima tes, and DEEM (ver. 7.81) default processing factors. The chronic drinking water estimat e of 0.0385 ppm, provided by the Environmental Fate and Effects Division (EFED), was directly incorporated into the ch ronic assessment. For the U.S. population the dietary risk (food plus water) utilizes 18% ofthe chronic populationadjusted dose (cPAD). The chronic dietary ri sk estimate for the highest reported exposed population subgroup, children 1 to 2 year s old, utilizes 71% of the cPAD.

Cancer Dietary (Food and Drinking Water) Exposure Results and Characterization

Fludioxonil is classified as a Gr oup D chemical - not classifiable as to human carcinogenicity; therefore, a cancer dietary exposure a nd risk assessment was not performed.

I. Introduction

Dietary risk assessment incorporat es both exposure and toxicity of a given pesticide. For acute and chronic assessments, the risks are expressed as a percentage of a maximum acceptable dose. This is the PAD, which HED has concluded will re sult in no unreasonable adverse health effects. The PAD is equivalent to the point of depa rture (POD; e.g., NOAEL, LOAEL) divided by the required uncertainty or safety fact ors. Dietary risk is expresse d as a percentage of the PAD.

For non-cancer chronic exposures, HED is concer ned when estimated dietary risk exceeds 100% of the PAD. References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site: “A vailable Information on Assessing Exposure from Pesticides, A User’s Guide”, 21/06/2000, we b link: http://www.epa.gov/fedrgstr/EPAPEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (08/20/1999).

The most recent dietary risk assessment for fludioxonil was conducted by G. Kramer (05/21/2012, D389981).

II. Residue Information

Established Tolerances: Permanent tolerances for residue s of fludioxonil are listed in 40 CFR §180.516 and are expressed in terms of fludioxon il (4-(2, 2-difluoro-1, 3-benzodioxol-4-yl)-1 H

– pyrrole-3-carbonitrile) in/on a va riety of plant commodities.Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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### Residue of Concern: The HED Metabolism Assessment Review Committee (MARC) has determined that the residue of concern for purposes of tolerance enforcement and risk assessment, is the parent fludioxonil (Memo, 01/18/2000, W. Donovan, et al ., D262022). As part of a previous tolerance petition memo, an additional plant metabolism study reconfirmed fludioxonil as the only residue of concern (Memo, 02/12/2003, T. Bloem, D287808). The nature of the residues in livestock is also unders tood based on the adequate goat and hen metabolism studies. For purposes of tolerance enforcement a nd risk assessment, the residues of concern in ruminants are fludioxonil and Metabolite B-1, an d the residues of concern in poultry are fludioxonil, CGA-344623, and Metabolite I-1.

Recommended Tolerances: As part of the current petiti on, HED recommends establishing the following tolerances:

CFR §180.516 (a) General. (1) is as follows: Tolerances are established for residues of the fungicide fludioxonil, including its metabolites and degradates, in or on the commodities in the table below. Compliance with the tolerance levels specified below is to be determined by measuring only fludioxonil, 4-( 2,2-difluoro-1,3-benzodioxol-4-yl)-1- H -pyrrole-3-carbonitrile).

Carrot 7.0 ppm Fruit, stone, group 12-12 5.0 ppm Rapeseed, subgroup 20A, except flax seed 0.01 ppm

No new data were submitted to support tole rances on stone fruit, group 12-12 and rapeseed, subgroup 20A. Residue data were submitted to support the post-harvest use on carrots. For stone fruit and rapeseed, the petitioner has requested that existing tolerances be expanded to their respective crop groups or crop subgroups.

Residue Data Used for Chronic Assessments : Established and recommended tolerance-level residues, 100% CT, and DEEM (ver. 7.81) defaul t processing factors we re utilized for the chronic assessment.

Fish: The USDA Pesticide Data Program (PDP) di d monitor for pesticide residues in catfish during 2008, 2009, 2010, 2011, and 2012. In general, pest icide residues would not be expected to be found in fish unless the pesticide bioaccumu lates or has an aquatic use. To determine whether or not residues are present in fish, HED now routinely checks PDP monitoring data regardless of the pesticide’s uses and physicoc hemical properties. However, PDP did not analyze catfish samples for residues of fludioxonil or its metabolites. As a result, residues in fish were not included in the assessment.

III. Drinking Water Data

Estimated drinking water concentrations (EDWCs) were generated using EFED’s standard suite of models (Memo, 09/17/2014, C. Sutton, D421066). The Pesticide Root Zone Model (PRZM, v3.12.2, May 2005) and Exposure Analysis Mode ling System (EXAMS, v 2.98.4.6, April 2005) are simulation models used to generate EDWCs of fludioxonil residues that may occur in surface water used as drinking water. The PRZM model simulates pesticide movement and transformation on and across the ag ricultural field resulting fromcrop applications. Percentcropped areas that account for the maximum area w ithin a watershed that may be planted with the modeled crop are applied to concentrations predicted by PRZM/EXAMS . EFED noted thatFludioxonil Dietary Exposure and Risk Assessment DP# 426862

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### an additional model (PRZM-GW) was not used as the contribution of residues in groundwater is negligible in comparison to surface water residu es. The models and their descriptions are available at the EPA internet site: h ttp://www.epa.gov/oppefed1/models/water/.

Screening Concentration in Ground Water (SCI -GROW v 2.3, Jul. 29, 2 003) is a regression model used as a screening tool to estimate pes ticide concentrations found in groundwater used as drinking water. The output of SCI-GROW repres ents the concentratio ns of fludioxonil that might be expected in shallow unc onfined aquifers under sandy soils , which is representative of the groundwater most vulnerable to pesticide co ntamination and likely to serve as a drinking

water source.

The maximum proposed application rate among a ll new proposed uses (for stone fruit group 12- 12) is 0.46 lbs ai/A/application, applied on ce per cropping season. Because the maximum proposed application rate among all of the uses c onsidered for this assessment is less than the rates previously assessed by EF ED for ornamentals, the EDWC s based on use on ornamentals are recommended for use in the human health dietary assessment. However, based on information provided in S yngenta’s 9/9/2011 submission “ Fludioxonil Registration Review Public Comments Response to Initial 60-Day Comment Period, Case Number: 7017, Docket Number: EPA-HQ-OPP-2010-1067,” EFED concurs that the us e of the container-grown ornamentals application rate is not appropriate for estimating EDWCs. As noted by the registrant, the strong adsorption of the pesticide to the potting media used for container-grown ornamentals, as well as the use of containers, re sults in attenuation of pesticide movement from the containers to the underlying soil in the field, there by reducing potential runoff of the pesticide. Thus, EFED did not ge nerate new EDWCs for this assessment. The values in the Tier I drinking water assessment are based on the us e of fludioxonil on field- grown ornamentals at one application of 2 lb ai/A/yr. The resulti ng acute and chronic EDWCs in surface water were 83.8 ppb (1-in-10-year acute estimate) and 38.5 ppb (1-in-10-year chronic estimate), respectively. The EDWC for groundwater (for both acute and chronic analysis) is 0.2 ppb. Since the surface water concentrations were th e highest; the chronic dietary analysis was conducted assuming water residues of 0.0385 ppm for all water sources (direct and indirect).

Table 2. Tier II Estimated Drinkin g Water Concentrations (EDWCs) Resultin g From Applications of Fludioxonil on Ornamentals (Total Rate of 4 lb ai/A/yr). Drinking water source (model) Use 1-in-10-year acute (μg/L) 1-in-10-year chronic (μg/L)

Surface water (PRZM/EXAMS) Container-grown ornamental 83.8 38.5

Groundwater (SCI-GROW) Container-grown ornamental 0.2 0.2



### IV. DEEM-FCID Program and Consumption Information

A fludioxonil chronic dietary exposure assessmen t was conducted using DEEM-FCID, ver. 3.16, which uses food consumption data from US DA’s NHANES/WWEIA. Foods “as consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fres h or N/S, baked) using publicly available recipe translation files developed jo intly by USDA Agricultural Rese arch Service and EPA. For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups, but for acute expo sure assessment are retained as individualFludioxonil Dietary Exposure and Risk Assessment DP# 426862

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### consumption events. Based on analysis of the c onsumption data, which t ook into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. popul ation, all infants (< 1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, adu lts 20-49, females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an esti mate of the residue level in each food or foodform (e.g., orange or orange juice) on the f ood commodity residue list is multiplied by the average daily consumption estimate for that food/f ood form to produce a residue intake estimate. The resulting residue intake estimate for each f ood/food form is summed w ith the residue intake estimates for all other food/food forms on the comm odity residue list to arrive at the total average estimated exposure. Exposure is expres sed in mg/kg body weight/day and as a percent of the cPAD. This procedure is performed for each population subgroup.

V. Toxicological Information

RAB1 previously reviewed the fludioxonil t oxicological database (Memo, 5/21/2012, W. Wassell, D389613). Based on toxicological consid erations and a review of the hazard and exposure data, the FQPA safety factor was reduced to 1X when chronic dietary exposures were assessed. HED’s Cancer Peer Review Committe e has classified fludioxonil as a “Group D” chemical - not classifiable as to human carcinogenicity.

The HED Hazard Identification Assessment Re view Committee previously reviewed the fludioxonil toxicological database (HED Doc. No. 013806, W. Dykstra, 10/13/1999; TXR No. 0050427, W. Dykstra, 1/29/2002). The toxicological endpoints used for dietary exposure for fludioxonil are summarized in Table 3, below.Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 6 of 17 Table 3. Summary of Toxicological Doses and Endpoints for Fludioxonil for Use in Dietary Exposure Risk Assessments.

Exposure/ Scenario Point of Departure

(POD) Uncertainty/FQPA Safety Factors RfD, PAD Study and Toxicological Effects Acute Dietary (General Population,

including Infants and Children) There were no appropriate toxicol ogical effects attributable to a single exposure (dose) observed in available oral toxicity studies, including ma ternal toxicity in the developmental toxicity studies. Therefore, a dose and endpoint were not identified for this risk assessment.

Chronic Dietary (All Populations) NOAEL = 33.1 mg/kg/day UF A = 10X UF H = 10X FQPA SF = 1X Chronic RfD = 0.33 mg/kg/day cPAD = 0.33

mg/kg/day Chronic toxicity in dogs. LOAEL = 297.8 mg/kg/day based upon decreased absolute body weights, increased platelets and fibrin in both sexes, cholesterol in males, and increased alkaline phosphatase release in both sexes. Enlarged livers in two females were observed along with biliary epithelial cell proliferation in one female. Cancer (oral, dermal, inhalation) Classification: HED’s Cancer Peer Re view Committee has classified fludioxonil as a Group D chemical - not classifiable as to human carcinogenicity. Point of departure (POD) = A data point or an estimated point that is derived from observed dose-response data and used to mark the beginning of extrapolation to determine risk associated with lower en vironmentally relevant human exposures. NOAEL = no-observed adverse-effect level. LOAEL = lowest-observed adverse-effect level. UF = uncertainty factor. UF A = extrapolation from animal to human (intraspecies). UF H = potential variation in sensitivity among members of the human population (inter species). FQPA SF = FQPA Safety Factor. PAD = population-adjusted dose (a = acute, c = chronic) . RfD = reference dose. N/A = not applicable.



### VI. Results/Discussion

For chronic assessments, HED is concerned when dietary risk exceeds 100% of the PAD. The DEEM-FCID analyses estimate the dietary e xposure of the U.S. population and various population subgroups. The results reported in the Summary Table (Table 4) are for the general U.S. population, all infants (<1 year old), child ren 1-2, children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50+ years.

Results of Acute and Chronic Dietary Exposure Analyses

The chronic dietary risk for the U.S. population (food plus water) for fludioxonil utilizes 18% of the cPAD. The chronic dietary risk for the highest exposed population subgroup, children 1-2 years old, is 71% of the cPAD.

The results of the acute and chronic dietary e xposure and risk analys es are reported in the Summary Table (Table 4, below).Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 7 of 17 Table 4. Summary of Dietary Exposure (Food Pl us Water) and Risk Assessment for Fludioxonil.

Population Subgroup Acute Dietary (95th Percentile) Chronic Dietary Dietary Exposure (mg/kg/day) % aPAD* Dietary Exposure (mg/kg/day) % cPAD* General U.S. Population

N/A 0.060754 18 All Infants (<1 year old) 0.096650 29 Children 1-2 years old 0.232759 71 Children 3-5 years old 0.171557 52 Children 6-12 years old 0.083311 25 Youth 13-19 years old 0.049740 15 Adults 20-49 years old 0.045760 14 Adults 50+ years old 0.045352 14 Females 13-49 years old 0.046659 14 * % PADs are reported to 2 significant figures. The values for the highest exposed population for each type of risk assessment are bolded.



### VII. Characterizati on of Inputs/Outputs

These analyses are conservative dietary expos ure assessments. Further refinement to the analyses could be made through the use of anticip ated residue estimates (ARs), incorporation of percent CT estimates, and/or monitoring data that better reflect re sidues at the time of consumption. However, refined analyses are not required at this time since the unrefined estimates are not of concern to HED.

An unrefined chronic dietary exposure and riskassessment was performed assuming tolerancelevel residues, 100% CT estimates, and DEEM (ver. 7.81) default processing factors. The chronic drinking water estimate of 0.0385 ppm, provi ded by the EFED, was directly incorporated into the chronic assessment. For the U.S. population the diet ary exposure (food plus water) utilizes 18% of the cPAD. The chronic dietar y exposure estimate for the highest reported exposed population subgroup, children 1 to 2 years old, utilizes 71% of the cPAD.

HED concludes that the exposure estimates pr ovided in this document are unlikely to underestimate actual exposure for the following reas ons: (1) the analysis incorporated tolerancelevel residues; and (2) the surf ace drinking water estimates were from a conservative drinking water assessment and are based upon the ma ximum use rate pattern on the label.

VIII. Conclusions

Chronic dietary (food plus drinki ng water) dietary exposure and ri sk assessments were conducted for fludioxonil to support the proposed Secti on 3 uses of fludioxonil on carrots, rapeseed (subgroup 20A) and stone fruit, group 12-12. Th e chronic dietary (food plus drinking water) exposure to fludioxonil is below HED’s level of concern for the general U.S. population and all population subgroups. The chronic dietary risk ut ilizes 18% of the cPAD for the general U.S. population; and, for the most hi ghly exposed population subgroup (children 1-2 years old) 71% of the cPAD.Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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### IX. List of Attachments

Attachment 1: DEEM-FCID Chronic Residue File Attachment 2: DEEM-FCID Chroni c Exposure and Risk Estimates

ID Number: 4E8272, 4F8277 DP #: D462862 PC Code: 071503Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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### Attachment 1: DEEM-FCID TM 

### Chronic Residue File

Filename: J:\Work Files\$ Fludioxonil\Carrot - 4E8272\DEEM\04_07_2015_chronic.r08 Chemical: Fludioxonil RfD(Chronic): .33 mg/kg bw/day NOEL(Chronic): 33.1 mg/kg bw/day RfD(Acute): 0 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day Date created/last modified: 04-07-2015/11:09:20 Program ver. 3.16, 03-08-d

----------------------------------------------------------------------------- EPA Crop Def Res Adj.Factors Comment Code Grp Commodity Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ --------- 0101050000 1AB Beet, garden, roots 0.750000 1.000 1.000 0101050001 1AB Beet, garden, roots-babyfood 0.750000 1.000 1.000 0101052000 1A Beet, sugar 0.020000 1.000 1.000 0101052001 1A Beet, sugar-babyfood 0.020000 1.000 1.000 0101053000 1A Beet, sugar, molasses 0.020000 1.000 1.000 0101053001 1A Beet, sugar, molasses-babyfood 0.020000 1.000 1.000 0101067000 1AB Burdock 0.750000 1.000 1.000 0101078000 1AB Carrot 7.000000 1.000 1.000 0101078001 1AB Carrot-babyfood 7.000000 1.000 1.000 0101079000 1AB Carrot, juice 7.000000 1.000 1.000 0101084000 1AB Celeriac 0.750000 1.000 1.000 0101100000 1AB Chicory, roots 0.750000 1.000 1.000 0101168000 1AB Ginseng, dried 4.000000 1.000 1.000 0101190000 1AB Horseradish 0.750000 1.000 1.000 0101250000 1AB Parsley, turnip rooted 0.750000 1.000 1.000 0101251000 1AB Parsnip 0.750000 1.000 1.000 0101251001 1AB Parsnip-babyfood 0.750000 1.000 1.000 0101314000 1AB Radish, roots 0.750000 1.000 1.000 0101316000 1AB Radish, Oriental, roots 0.750000 1.000 1.000 0101327000 1AB Rutabaga 0.750000 1.000 1.000 0101331000 1AB Salsify, roots 0.750000 1.000 1.000 0101388000 1AB Turnip, roots 0.750000 1.000 1.000 0103015000 1CD Arrowroot, flour 6.000000 1.000 1.000 0103015001 1CD Arrowroot, flour-babyfood 6.000000 1.000 1.000 0103017000 1CD Artichoke, Jerusalem 6.000000 1.000 1.000 0103082000 1CD Cassava 6.000000 1.000 1.000 0103082001 1CD Cassava-babyfood 6.000000 1.000 1.000 0103139000 1CD Dasheen, corm 6.000000 1.000 1.000 0103166000 1CD Ginger 6.000000 1.000 1.000 0103166001 1CD Ginger-babyfood 6.000000 1.000 1.000 0103167000 1CD Ginger, dried 6.000000 1.000 1.000 0103296000 1C Potato, chips 6.000000 1.000 1.000 0103297000 1C Potato, dry (granules/ flakes) 6.000000 6.500 1.000 0103297001 1C Potato, dry (granules/ flakes)-b 6.000000 6.500 1.000 0103298000 1C Potato, flour 6.000000 6.500 1.000 0103298001 1C Potato, flour-babyfood 6.000000 6.500 1.000 0103299000 1C Potato, tuber, w/peel 6.000000 1.000 1.000 0103299001 1C Potato, tuber, w/peel-babyfood 6.000000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 6.000000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel-babyfood 6.000000 1.000 1.000 0103366000 1CD Sweet potato 6.000000 1.000 1.000 0103366001 1CD Sweet potato-babyfood 6.000000 1.000 1.000 0103371000 1CD Tanier, corm 6.000000 1.000 1.000 0103387000 1CD Turmeric 6.000000 1.000 1.000 0103406000 1CD Yam, true 8.000000 1.000 1.000 0103407000 1CD Yam bean 6.000000 1.000 1.000 0200051000 2 Beet, garden, tops 30.000000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 10 of 17 0200101000 2 Chicory, tops 30.000000 1.000 1.000 0200140000 2 Dasheen, leaves 30.000000 1.000 1.000 0200315000 2 Radish, tops 30.000000 1.000 1.000 0200317000 2 Radish, Oriental, tops 30.000000 1.000 1.000 0200332000 2 Salsify, tops 30.000000 1.000 1.000 0301165000 3A Garlic, bulb 0.500000 1.000 1.000 0301165001 3A Garlic, bulb-babyfood 0.500000 1.000 1.000 0301237000 3A Onion, bulb 0.500000 1.000 1.000 0301237001 3A Onion, bulb-babyfood 0.500000 1.000 1.000 0301238000 3A Onion, bulb, dried 0.500000 9.000 1.000 0301238001 3A Onion, bulb, dried-babyfood 0.500000 9.000 1.000 0301338000 3A Shallot, bulb 0.500000 1.000 1.000 0302103000 3B Chive, fresh leaves 7.000000 1.000 1.000 0302198000 3B Leek 7.000000 1.000 1.000 0302239000 3B Onion, green 7.000000 1.000 1.000 0302338500 3B Shallot, fresh leaves 7.000000 1.000 1.000 0401005000 4A Amaranth, leafy 30.000000 1.000 1.000 0401018000 4A Arugula 30.000000 1.000 1.000 0401104000 4A Chrysanthemum, garland 30.000000 1.000 1.000 0401133000 4A Cress, garden 30.000000 1.000 1.000 0401134000 4A Cress, upland 30.000000 1.000 1.000 0401138000 4A Dandelion, leaves 30.000000 1.000 1.000 0401150000 4A Endive 30.000000 1.000 1.000 0401204000 4A Lettuce, head 30.000000 1.000 1.000 0401205000 4A Lettuce, leaf 30.000000 1.000 1.000 0401248000 4A Parsley, leaves 30.000000 1.000 1.000 0401313000 4A Radicchio 30.000000 1.000 1.000 0401355000 4A Spinach 30.000000 1.000 1.000 0401355001 4A Spinach-babyfood 30.000000 1.000 1.000 0402076000 4B Cardoon 15.000000 1.000 1.000 0402085000 4B Celery 15.000000 1.000 1.000 0402085001 4B Celery-babyfood 15.000000 1.000 1.000 0402086000 4B Celery, juice 15.000000 1.000 1.000 0402087000 4B Celtuce 15.000000 1.000 1.000 0402152000 4B Fennel, Florence 15.000000 1.000 1.000 0402322000 4B Rhubarb 15.000000 1.000 1.000 0402367000 4B Swiss chard 15.000000 1.000 1.000 0501061000 5A Broccoli 2.000000 1.000 1.000 0501061001 5A Broccoli-babyfood 2.000000 1.000 1.000 0501062000 5A Broccoli, Chinese 2.000000 1.000 1.000 0501064000 5A Brussels sprouts 2.000000 1.000 1.000 0501069000 5A Cabbage 2.000000 1.000 1.000 0501071000 5A Cabbage, Chinese, napa 2.000000 1.000 1.000 0501072000 5A Cabbage, Chinese, mustard 2.000000 1.000 1.000 0501083000 5A Cauliflower 2.000000 1.000 1.000 0501196000 5A Kohlrabi 2.000000 1.000 1.000 0502063000 5B Broccoli raab 10.000000 1.000 1.000 0502070000 5B Cabbage, Chinese, bok choy 10.000000 1.000 1.000 0502117000 5B Collards 10.000000 1.000 1.000 0502194000 5B Kale 10.000000 1.000 1.000 0502229000 5B Mustard greens 10.000000 1.000 1.000 0502318000 5B Rape greens 10.000000 1.000 1.000 0502389000 5B Turnip, greens 10.000000 1.000 1.000 0600347000 6 Soybean, seed 0.010000 1.000 1.000 0600349000 6 Soybean, soy milk 0.010000 1.000 1.000 0600349001 6 Soybean, soy milk-babyfood or in 0.010000 1.000 1.000 0600350000 6 Soybean, oil 0.010000 1.000 1.000 0600350001 6 Soybean, oil-babyfood 0.010000 1.000 1.000 0601043000 6A Bean, snap, succulent 0.400000 1.000 1.000 0601043001 6A Bean, snap, succulent-babyfood 0.400000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 11 of 17 0601257000 6A Pea, edible podded, succulent 0.400000 1.000 1.000 0601349500 6AB Soybean, vegetable 0.010000 1.000 1.000 0602031000 6B Bean, broad, succulent 0.400000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 0.400000 1.000 1.000 0602037000 6B Bean, lima, succulent 0.400000 1.000 1.000 0602255000 6B Pea, succulent 0.010000 1.000 1.000 0602255001 6B Pea, succulent-babyfood 0.010000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.010000 1.000 1.000 0603030000 6C Bean, black, seed 0.400000 1.000 1.000 0603032000 6C Bean, broad, seed 0.400000 1.000 1.000 0603034000 6C Bean, cowpea, seed 0.400000 1.000 1.000 0603035000 6C Bean, great northern, seed 0.400000 1.000 1.000 0603036000 6C Bean, kidney, seed 0.400000 1.000 1.000 0603038000 6C Bean, lima, seed 0.400000 1.000 1.000 0603039000 6C Bean, mung, seed 0.400000 1.000 1.000 0603040000 6C Bean, navy, seed 0.400000 1.000 1.000 0603041000 6C Bean, pink, seed 0.400000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.400000 1.000 1.000 0603098000 6C Chickpea, seed 0.400000 1.000 1.000 0603098001 6C Chickpea, seed-babyfood 0.400000 1.000 1.000 0603099000 6C Chickpea, flour 0.400000 1.000 1.000 0603182000 6C Guar, seed 0.400000 1.000 1.000 0603182001 6C Guar, seed-babyfood 0.400000 1.000 1.000 0603203000 6C Lentil, seed 0.400000 1.000 1.000 0603256000 6C Pea, dry 0.400000 1.000 1.000 0603256001 6C Pea, dry-babyfood 0.400000 1.000 1.000 0603258000 6C Pea, pigeon, seed 0.400000 1.000 1.000 0603348000 6C Soybean, flour 0.010000 1.000 1.000 0603348001 6C Soybean, flour-babyfood 0.010000 1.000 1.000 0801374000 8A Tomatillo 0.500000 1.000 1.000 0801375000 8A Tomato 5.000000 1.000 1.000 0801375001 8A Tomato-babyfood 5.000000 1.000 1.000 0801376000 8A Tomato, paste 5.000000 5.400 1.000 0801376001 8A Tomato, paste-babyfood 5.000000 5.400 1.000 0801377000 8A Tomato, puree 5.000000 3.300 1.000 0801377001 8A Tomato, puree-babyfood 5.000000 3.300 1.000 0801378000 8A Tomato, dried 5.000000 14.300 1.000 0801378001 8A Tomato, dried-babyfood 5.000000 14.300 1.000 0801379000 8A Tomato, juice 5.000000 1.500 1.000 0801380000 8A Tomato, Tree 5.000000 1.000 1.000 0802148000 8BC Eggplant 0.500000 1.000 1.000 0802234000 8BC Okra 0.500000 1.000 1.000 0802270000 8B Pepper, bell 0.500000 1.000 1.000 0802270001 8B Pepper, bell-babyfood 0.500000 1.000 1.000 0802271000 8B Pepper, bell, dried 0.500000 1.000 1.000 0802271001 8B Pepper, bell, dried-babyfood 0.500000 1.000 1.000 0802272000 8BC Pepper, nonbell 0.500000 1.000 1.000 0802272001 8BC Pepper, nonbell-babyfood 0.500000 1.000 1.000 0802273000 8BC Pepper, nonbell, dried 0.500000 1.000 1.000 0901075000 9A Cantaloupe 0.450000 1.000 1.000 0901187000 9A Honeydew melon 0.450000 1.000 1.000 0901399000 9A Watermelon 0.450000 1.000 1.000 0901400000 9A Watermelon, juice 0.450000 1.000 1.000 0902021000 9B Balsam pear 0.450000 1.000 1.000 0902088000 9B Chayote, fruit 0.450000 1.000 1.000 0902102000 9B Chinese waxgourd 0.450000 1.000 1.000 0902135000 9B Cucumber 0.450000 1.000 1.000 0902308000 9B Pumpkin 0.450000 1.000 1.000 0902309000 9B Pumpkin, seed 0.450000 1.000 1.000 0902356000 9B Squash, summer 0.450000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 12 of 17 0902356001 9B Squash, summer-babyfood 0.450000 1.000 1.000 0902357000 9B Squash, winter 0.450000 1.000 1.000 0902357001 9B Squash, winter-babyfood 0.450000 1.000 1.000 1001106000 10A Citron 10.000000 1.000 1.000 1001107000 10A Citrus hybrids 10.000000 1.000 1.000 1001108000 10A Citrus, oil 500.000000 1.000 1.000 1001240000 10A Orange 10.000000 1.000 1.000 1001241000 10A Orange, juice 10.000000 1.800 1.000 1001241001 10A Orange, juice-babyfood 10.000000 1.800 1.000 1001242000 10A Orange, peel 10.000000 1.000 1.000 1001369000 10A Tangerine 10.000000 1.000 1.000 1001370000 10A Tangerine, juice 10.000000 2.300 1.000 1002197000 10B Kumquat 10.000000 1.000 1.000 1002199000 10B Lemon 10.000000 1.000 1.000 1002200000 10B Lemon, juice 10.000000 2.000 1.000 1002200001 10B Lemon, juice-babyfood 10.000000 2.000 1.000 1002201000 10B Lemon, peel 10.000000 1.000 1.000 1002206000 10B Lime 10.000000 1.000 1.000 1002207000 10B Lime, juice 10.000000 2.000 1.000 1002207001 10B Lime, juice-babyfood 10.000000 2.000 1.000 1003180000 10C Grapefruit 10.000000 1.000 1.000 1003181000 10C Grapefruit, juice 10.000000 2.100 1.000 1003307000 10C Pummelo 10.000000 1.000 1.000 1100007000 11 Apple, fruit with peel 5.000000 1.000 1.000 1100008000 11 Apple, peeled fruit 5.000000 1.000 1.000 1100008001 11 Apple, peeled fruit-babyfood 5.000000 1.000 1.000 1100009000 11 Apple, dried 5.000000 8.000 1.000 1100009001 11 Apple, dried-babyfood 5.000000 8.000 1.000 1100010000 11 Apple, juice 5.000000 1.300 1.000 1100010001 11 Apple, juice-babyfood 5.000000 1.300 1.000 1100011000 11 Apple, sauce 5.000000 1.000 1.000 1100011001 11 Apple, sauce-babyfood 5.000000 1.000 1.000 1100129000 11 Crabapple 5.000000 1.000 1.000 1100173500 11 Goji berry 0.500000 1.000 1.000 1100210000 11 Loquat 5.000000 1.000 1.000 1100266000 11 Pear 5.000000 1.000 1.000 1100266001 11 Pear-babyfood 5.000000 1.000 1.000 1100267000 11 Pear, dried 5.000000 6.250 1.000 1100268000 11 Pear, juice 5.000000 1.000 1.000 1100268001 11 Pear, juice-babyfood 5.000000 1.000 1.000 1100310000 11 Quince 5.000000 1.000 1.000 1201090000 12A Cherry 5.000000 1.000 1.000 1201090001 12A Cherry-babyfood 5.000000 1.000 1.000 1201091000 12A Cherry, juice 5.000000 1.500 1.000 1201091001 12A Cherry, juice-babyfood 5.000000 1.500 1.000 1202012000 12B Apricot 5.000000 1.000 1.000 1202012001 12B Apricot-babyfood 5.000000 1.000 1.000 1202013000 12B Apricot, dried 5.000000 6.000 1.000 1202014000 12B Apricot, juice 5.000000 1.000 1.000 1202014001 12B Apricot, juice-babyfood 5.000000 1.000 1.000 1202230000 12B Nectarine 5.000000 1.000 1.000 1202260000 12B Peach 5.000000 1.000 1.000 1202260001 12B Peach-babyfood 5.000000 1.000 1.000 1202261000 12B Peach, dried 5.000000 7.000 1.000 1202261001 12B Peach, dried-babyfood 5.000000 7.000 1.000 1202262000 12B Peach, juice 5.000000 1.000 1.000 1202262001 12B Peach, juice-babyfood 5.000000 1.000 1.000 1203285000 12C Plum 5.000000 1.000 1.000 1203285001 12C Plum-babyfood 5.000000 1.000 1.000 1203286000 12C Plum, prune, fresh 5.000000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 13 of 17 1203286001 12C Plum, prune, fresh-babyfood 5.000000 1.000 1.000 1203287000 12C Plum, prune, dried 5.000000 5.000 1.000 1203287001 12C Plum, prune, dried-babyfood 5.000000 5.000 1.000 1203288000 12C Plum, prune, juice 5.000000 1.400 1.000 1203288001 12C Plum, prune, juice-babyfood 5.000000 1.400 1.000 1301055000 13A Blackberry 5.000000 1.000 1.000 1301056000 13A Blackberry, juice 5.000000 1.000 1.000 1301056001 13A Blackberry, juice-babyfood 5.000000 1.000 1.000 1301058000 13A Boysenberry 5.000000 1.000 1.000 1301208000 13A Loganberry 5.000000 1.000 1.000 1301320000 13A Raspberry 5.000000 1.000 1.000 1301320001 13A Raspberry-babyfood 5.000000 1.000 1.000 1301321000 13A Raspberry, juice 5.000000 1.000 1.000 1301321001 13A Raspberry, juice-babyfood 5.000000 1.000 1.000 1302057000 13B Blueberry 2.000000 1.000 1.000 1302057001 13B Blueberry-babyfood 2.000000 1.000 1.000 1302136000 13B Currant 2.000000 1.000 1.000 1302137000 13B Currant, dried 2.000000 1.000 1.000 1302149000 13B Elderberry 2.000000 1.000 1.000 1302174000 13B Gooseberry 2.000000 1.000 1.000 1302191000 13B Huckleberry 2.000000 1.000 1.000 1304175000 13D Grape 2.000000 1.000 1.000 1304176000 13D Grape, juice 2.000000 1.200 1.000 1304176001 13D Grape, juice-babyfood 2.000000 1.200 1.000 1304179000 13D Grape, wine and sherry 2.000000 1.000 1.000 1304195000 13D Kiwifruit, fuzzy 20.000000 1.000 1.000 1307359000 13G Strawberry 3.000000 1.000 1.000 1307359001 13G Strawberry-babyfood 3.000000 1.000 1.000 1307360000 13G Strawberry, juice 3.000000 1.000 1.000 1400282000 14 Pistachio 0.100000 1.000 1.000 1500025000 15 Barley, pearled barley 0.020000 1.000 1.000 1500025001 15 Barley, pearled barley-babyfood 0.020000 1.000 1.000 1500026000 15 Barley, flour 0.020000 1.000 1.000 1500026001 15 Barley, flour-babyfood 0.020000 1.000 1.000 1500027000 15 Barley, bran 0.020000 1.000 1.000 1500065000 15 Buckwheat 0.020000 1.000 1.000 1500066000 15 Buckwheat, flour 0.020000 1.000 1.000 1500120000 15 Corn, field, flour 0.020000 1.000 1.000 1500120001 15 Corn, field, flour-babyfood 0.020000 1.000 1.000 1500121000 15 Corn, field, meal 0.020000 1.000 1.000 1500121001 15 Corn, field, meal-babyfood 0.020000 1.000 1.000 1500122000 15 Corn, field, bran 0.020000 1.000 1.000 1500123000 15 Corn, field, starch 0.020000 1.000 1.000 1500123001 15 Corn, field, starch-babyfood 0.020000 1.000 1.000 1500124000 15 Corn, field, syrup 0.020000 1.500 1.000 1500124001 15 Corn, field, syrup-babyfood 0.020000 1.500 1.000 1500125000 15 Corn, field, oil 0.020000 1.000 1.000 1500125001 15 Corn, field, oil-babyfood 0.020000 1.000 1.000 1500126000 15 Corn, pop 0.020000 1.000 1.000 1500127000 15 Corn, sweet 0.020000 1.000 1.000 1500127001 15 Corn, sweet-babyfood 0.020000 1.000 1.000 1500226000 15 Millet, grain 0.020000 1.000 1.000 1500231000 15 Oat, bran 0.020000 1.000 1.000 1500232000 15 Oat, flour 0.020000 1.000 1.000 1500232001 15 Oat, flour-babyfood 0.020000 1.000 1.000 1500233000 15 Oat, groats/rolled oats 0.020000 1.000 1.000 1500233001 15 Oat, groats/rolled oats-babyfood 0.020000 1.000 1.000 1500323000 15 Rice, white 0.020000 1.000 1.000 1500323001 15 Rice, white-babyfood 0.020000 1.000 1.000 1500324000 15 Rice, brown 0.020000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 14 of 17 1500324001 15 Rice, brown-babyfood 0.020000 1.000 1.000 1500325000 15 Rice, flour 0.020000 1.000 1.000 1500325001 15 Rice, flour-babyfood 0.020000 1.000 1.000 1500326000 15 Rice, bran 0.020000 1.000 1.000 1500326001 15 Rice, bran-babyfood 0.020000 1.000 1.000 1500328000 15 Rye, grain 0.020000 1.000 1.000 1500329000 15 Rye, flour 0.020000 1.000 1.000 1500344000 15 Sorghum, grain 0.020000 1.000 1.000 1500345000 15 Sorghum, syrup 0.020000 1.000 1.000 1500381000 15 Triticale, flour 0.020000 1.000 1.000 1500381001 15 Triticale, flour-babyfood 0.020000 1.000 1.000 1500401000 15 Wheat, grain 0.020000 1.000 1.000 1500401001 15 Wheat, grain-babyfood 0.020000 1.000 1.000 1500402000 15 Wheat, flour 0.020000 1.000 1.000 1500402001 15 Wheat, flour-babyfood 0.020000 1.000 1.000 1500403000 15 Wheat, germ 0.020000 1.000 1.000 1500404000 15 Wheat, bran 0.020000 1.000 1.000 1500405000 15 Wild rice 0.020000 1.000 1.000 1901028000 19A Basil, fresh leaves 10.000000 1.000 1.000 1901028001 19A Basil, fresh leaves-babyfood 10.000000 1.000 1.000 1901029000 19A Basil, dried leaves 65.000000 1.000 1.000 1901029001 19A Basil, dried leaves-babyfood 65.000000 1.000 1.000 1901102500 19A Chive, dried leaves 65.000000 1.000 1.000 1901118000 19A Cilantro, leaves 10.000000 1.000 1.000 1901118001 19A Cilantro, leaves-babyfood 10.000000 1.000 1.000 1901144000 19A Dillweed 10.000000 1.000 1.000 1901184000 19A Herbs, other 10.000000 1.000 1.000 1901184001 19A Herbs, other-babyfood 10.000000 1.000 1.000 1901202000 19A Lemongrass 10.000000 1.000 1.000 1901220000 19A Marjoram 10.000000 1.000 1.000 1901220001 19A Marjoram-babyfood 10.000000 1.000 1.000 1901249000 19A Parsley, dried leaves 65.000000 1.000 1.000 1901249001 19A Parsley, dried leaves-babyfood 65.000000 1.000 1.000 1901334000 19A Savory 10.000000 1.000 1.000 1902105000 19B Cinnamon 0.020000 1.000 1.000 1902105001 19B Cinnamon-babyfood 0.020000 1.000 1.000 1902119000 19B Coriander, seed 0.020000 1.000 1.000 1902119001 19B Coriander, seed-babyfood 0.020000 1.000 1.000 1902143000 19B Dill, seed 0.020000 1.000 1.000 1902274000 19B Pepper, black and white 0.020000 1.000 1.000 1902274001 19B Pepper, black and white-babyfood 0.020000 1.000 1.000 1902354000 19B Spices, other 0.020000 1.000 1.000 1902354001 19B Spices, other-babyfood 0.020000 1.000 1.000 2001163000 20A Flax seed, oil 0.050000 1.000 1.000 2001319000 20A Rapeseed, oil 0.010000 1.000 1.000 2001319001 20A Rapeseed, oil-babyfood 0.010000 1.000 1.000 2001336000 20A Sesame, seed 0.010000 1.000 1.000 2001336001 20A Sesame, seed-babyfood 0.010000 1.000 1.000 2001337000 20A Sesame, oil 0.010000 1.000 1.000 2001337001 20A Sesame, oil-babyfood 0.010000 1.000 1.000 2002330000 20B Safflower, oil 0.010000 1.000 1.000 2002330001 20B Safflower, oil-babyfood 0.010000 1.000 1.000 2002364000 20B Sunflower, seed 0.010000 1.000 1.000 2002365000 20B Sunflower, oil 0.010000 1.000 1.000 2002365001 20B Sunflower, oil-babyfood 0.010000 1.000 1.000 2003128000 20C Cottonseed, oil 0.050000 1.000 1.000 2003128001 20C Cottonseed, oil-babyfood 0.050000 1.000 1.000 3100044000 31 Beef, meat 0.010000 1.000 1.000 3100044001 31 Beef, meat-babyfood 0.010000 1.000 1.000 3100045000 31 Beef, meat, dried 0.010000 1.920 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 15 of 17 3100046000 31 Beef, meat byproducts 0.050000 1.000 1.000 3100046001 31 Beef, meat byproducts-babyfood 0.050000 1.000 1.000 3100047000 31 Beef, fat 0.050000 1.000 1.000 3100047001 31 Beef, fat-babyfood 0.050000 1.000 1.000 3100048000 31 Beef, kidney 0.050000 1.000 1.000 3100049000 31 Beef, liver 0.050000 1.000 1.000 3100049001 31 Beef, liver-babyfood 0.050000 1.000 1.000 3200169000 32 Goat, meat 0.010000 1.000 1.000 3200170000 32 Goat, meat byproducts 0.050000 1.000 1.000 3200171000 32 Goat, fat 0.050000 1.000 1.000 3200172000 32 Goat, kidney 0.050000 1.000 1.000 3200173000 32 Goat, liver 0.050000 1.000 1.000 3300189000 33 Horse, meat 0.010000 1.000 1.000 3500339000 35 Sheep, meat 0.010000 1.000 1.000 3500339001 35 Sheep, meat-babyfood 0.050000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.050000 1.000 1.000 3500341000 35 Sheep, fat 0.050000 1.000 1.000 3500341001 35 Sheep, fat-babyfood 0.050000 1.000 1.000 3500342000 35 Sheep, kidney 0.050000 1.000 1.000 3500343000 35 Sheep, liver 0.050000 1.000 1.000 3600222000 36 Milk, fat 0.010000 1.000 1.000 3600222001 36 Milk, fat-baby food/infant formu 0.010000 1.000 1.000 3600223000 36 Milk, nonfat solids 0.010000 1.000 1.000 3600223001 36 Milk, nonfat solids-baby food/in 0.010000 1.000 1.000 3600224000 36 Milk, water 0.010000 1.000 1.000 3600224001 36 Milk, water-babyfood/infant form 0.010000 1.000 1.000 3600225001 36 Milk, sugar (lactose)-baby food/ 0.010000 1.000 1.000 8601000000 86A Water, direct, all sources 0.038500 1.000 1.000 8602000000 86B Water, indirect, all sources 0.038500 1.000 1.000 9500001000 O Acerola 5.000000 1.000 1.000 9500019500 O Atemoya 20.000000 1.000 1.000 9500020000 O Avocado 5.000000 1.000 1.000 9500074000 O Canistel 5.000000 1.000 1.000 9500089000 O Cherimoya 20.000000 1.000 1.000 9500151000 O Feijoa 5.000000 1.000 1.000 9500177000 O Grape, leaves 2.000000 1.000 1.000 9500178000 O Grape, raisin 2.000000 4.300 1.000 9500183000 O Guava 5.000000 1.000 1.000 9500183001 O Guava-babyfood 5.000000 1.000 1.000 9500209000 O Longan 20.000000 1.000 1.000 9500211000 O Lychee 20.000000 1.000 1.000 9500212000 O Lychee, dried 20.000000 1.850 1.000 9500214000 O Mamey apple 5.000000 1.000 1.000 9500215000 O Mango 5.000000 1.000 1.000 9500215001 O Mango-babyfood 5.000000 1.000 1.000 9500216000 O Mango, dried 5.000000 1.000 1.000 9500217000 O Mango, juice 5.000000 1.000 1.000 9500217001 O Mango, juice-babyfood 5.000000 1.000 1.000 9500245000 O Papaya 5.000000 1.000 1.000 9500245001 O Papaya-babyfood 5.000000 1.000 1.000 9500246000 O Papaya, dried 5.000000 1.800 1.000 9500247000 O Papaya, juice 5.000000 1.500 1.000 9500252000 O Passionfruit 5.000000 1.000 1.000 9500252001 O Passionfruit-babyfood 5.000000 1.000 1.000 9500253000 O Passionfruit, juice 5.000000 1.000 1.000 9500253001 O Passionfruit, juice-babyfood 5.000000 1.000 1.000 9500263000 O Peanut 0.010000 1.000 1.000 9500264000 O Peanut, butter 0.010000 1.890 1.000 9500265000 O Peanut, oil 0.010000 1.000 1.000 9500279000 O Pineapple 20.000000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 16 of 17 9500279001 O Pineapple-babyfood 20.000000 1.000 1.000 9500280000 O Pineapple, dried 20.000000 5.000 1.000 9500281000 O Pineapple, juice 20.000000 1.700 1.000 9500281001 O Pineapple, juice-babyfood 20.000000 1.700 1.000 9500289000 O Pomegranate 5.000000 1.000 1.000 9500333000 O Sapote, Mamey 5.000000 1.000 1.000 9500346000 O Soursop 20.000000 1.000 1.000 9500351000 O Spanish lime 20.000000 1.000 1.000 9500358000 O Starfruit 5.000000 1.000 1.000 9500361000 O Sugar apple 20.000000 1.000 1.000 9500398000 O Watercress 7.000000 1.000 1.000Fludioxonil Dietary Exposure and Risk Assessment DP# 426862

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Page 17 of 17 

### Attachment 2: DEEM-FCID Chroni c Exposure and Risk Estimates

US EPA Ver. 3.16, 03-08-d DEEM-FCID Chronic analysis for FLUDIOXONIL NHANES 2003-2008 2-day Residue file name: J:\Work Files\$ Fludioxonil\Carrot - 4E8272\DEEM\06_30_2015_chronic.r08 Adjustment factor #2 NOT used. Analysis Date 06-30-2015/15:09:41 Residue file dated: 06-30-2015/15:09:04 Reference dose (RfD, Chronic) = .33 mg/kg bw/day

============================================================================= Total exposure by population subgroup

----------------------------------------------------------------------------- Total Exposure

----------------------------------- Population mg/kg Percent of Subgroup body wt/day Rfd

-------------------------------------- ------------- ---------------- Total US Population 0.060754 18.4% Hispanic 0.078007 23.6% Non-Hisp-White 0.056075 17.0% Non-Hisp-Black 0.065624 19.9% Non-Hisp-Other 0.066796 20.2% Nursing Infants 0.059931 18.2% Non-Nursing Infants 0.113049 34.3% Female 13+ PREG 0.066731 20.2% Children 1-6 0.185664 56.3% Children 7-12 0.075819 23.0% Male 13-19 0.051744 15.7% Female 13-19/NP 0.047767 14.5% Male 20+ 0.044191 13.4% Female 20+/NP 0.046126 14.0% Seniors 55+ 0.045187 13.7% All Infants 0.096650 29.3% Female 13-50 0.046866 14.2% Children 1-2 0.232759 70.5% Children 3-5 0.171557 52.0% Children 6-12 0.083311 25.2% Youth 13-19 0.049740 15.1% Adults 20-49 0.045760 13.9% Adults 50-99 0.045352 13.7% Female 13-49 0.046659 14.1%

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