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Tebufenpyrad Preliminary Work Plan – Table of Contents 

OVERVIEW ................................................................................................................................... 3

STATUTORY AND REGULATORY AUTHORITY ................................................................... 3

CHEMICAL FACTS ...................................................................................................................... 4

NEXT STEPS ................................................................................................................................. 4 

References:

This Preliminary Work Plan summarizes the Environmental Protection Agency’s current position 

based on the following documents: 

1. BEAD Chemical Profile for Registration Review: Tebufenpyrad (090102). Colwell Cook, 

Jihad Alsadek, and Stephen Smearman. April 15, 2014. 

2. Voluntary Cancellation of Tebufenpyrad Registrations (AC 801, 757 Miticide-Insecticide 

EPA Reg. No. 71711-22 and AC 801, 757 3EC Miticide-Insecticide EPA Reg. No. 71711-

23). Lydia Cox. April 8, 2014. 

3. Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations. 

[EPA–HQ–OPP–2009–1017; FRL–9914–36; 45803.] Richard P. Keigwin, Jr. August 6, 

2014. 

These documents for the tebufenpyrad registration review case may be found in the docket EPAHQ-OPP-2014-0218 at http://www.regulations.gov. 
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OVERVIEW 

The docket for tebufenpyrad is now open, initiating the public comment period for the 

registration review (docket number EPA-HQ-OPP-2014-0218) associated with this Preliminary 

Work Plan (PWP). Tebufenpyrad is an insecticide/miticide registered for use on ornamental 

plants grown in commercial greenhouses for the control of mites, aphids, grape mealybug, pear 

psylla, serpentine leafminer, thrips, and whiteflies. 

Prior to initiation of the registration review for tebufenpyrad, the sole registrant of tebufenpyrad 

products, Nichino America, Inc., informed the Agency that it was intending to request 

voluntarily cancellation of all of its tebufenpyrad product registrations (EPA Reg. Nos. 71711-

22, technical formulation, and 71711-23, end use formulation). On April 8, 2014, Nichino 

America, Inc., submitted a letter requesting voluntary cancellation of all of their products 

containing the active ingredient tebufenpyrad and waiving the 180-day public comment period in 

lieu of a 30-day public comment period under FIFRA Section 6(f). These two products are the 

last tebufenpyrad pesticide product registrations in the United States. A copy of the request for 

voluntary cancellation and the Federal Register Notice announcing its receipt by the Agency 

have been placed in the docket for this Registration Review. 

The Agency had intended to open the tebufenpyrad docket with a PWP that explained what 

EPA’s Office of Pesticide Programs knows about tebufenpyrad, highlighting anticipated data and 

assessment needs, identifying the types of information that would be especially useful to the 

Agency in conducting the review, and providing an anticipated timeline for completing the 

registration review for tebufenpyrad. However, due to the request from Nichino America, Inc. to 

voluntarily cancel all of its tebufenpyrad product registrations in the United States, the Agency 

anticipates closing this registration review case once all tebufenpyrad product registrations have 

been cancelled. Should these voluntary cancellations not occur, the Agency will amend this 

PWP and include, among other things, anticipated data and assessment needs and an anticipated 

timeline for the registration review. 

STATUTORY AND REGULATORY AUTHORITY 

The Food Quality Protection Act (FQPA) of 1996 mandated a registration review program. All 

pesticides distributed or sold in the United States (U.S.) generally must be registered by the 

Environmental Protection Agency (EPA or the Agency), based on scientific data showing that 

they will not cause unreasonable risks to human health or the environment when used as directed 

on product labeling. The registration review program is intended to make sure that, as the ability 

to assess risk evolves and as policies and practices change, all registered pesticides continue to 

meet the statutory standard of no unreasonable adverse effects to human health or the 

environment. Changes in science, public policy, and pesticide use practices will occur over time. 

Through the registration review program, the Agency periodically reevaluates pesticides to make 

sure that as change occurs, products in the marketplace can be used safely. Information on this 

program is provided on EPA’s website.1

 

1

 http://www.epa.gov/oppsrrd1/registration_review/ 
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The Agency is implementing the registration review program pursuant to Section 3(g) of the 

Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and will review each registered 

pesticide every 15 years to determine whether it continues to meet the FIFRA standard for 

registration. The regulations governing registration review begin at 40 CFR 155.40. The 

Agency will consider benefits information and data as required by FIFRA. The public phase of 

registration review begins when the initial docket is opened for each case. The docket is the 

Agency’s opportunity to state what it knows about the pesticide and what additional risk analyses 

and data or information it believes are needed to make a registration review decision. 

CHEMICAL FACTS 

Table 1 provides a summary of the chemical facts for tebufenpyrad. 

Table 1: Chemical Facts for Tebufenpyrad

PC code 090102 

Case Number 7435

CAS Number 119168-77-3

Year first registered 2002 

Pesticide Type Insecticide/Miticide 

Chemical class Pyrazole 

Reregistration Eligibility 

Decision (RED) 

Tebufenpyrad was registered after November 1984; therefore, it 

was not subject to reregistration. 

Cumulative group EPA has not made a common mechanism of toxicity finding as to 

tebufenpyrad and any other substances and tebufenpyrad does not 

appear to produce a toxic metabolite produced by other 

substances. 

40 CFR Citation There are no registered tebufenpyrad food/feed uses and no 

established tolerances for tebufenpyrad. 

Dual-use Conventional pesticidal uses only 

Non-pesticidal uses No non-pesticidal uses of tebufenpyrad 

Pesticide Re-evaluation 

Division, Chemical 

Review Manager 

Susan Bartow, bartow.susan@epa.gov, (703) 603-0065 

Registration Division, 

Product Manager 

Richard Gebken, gebken.richard@epa.gov, (703) 305-6701 

NEXT STEPS 

On August 6, 2014, EPA published a Federal Register Notice announcing receipt of the request 

to voluntarily cancel Nichino America, Inc. pesticide registrations with a 30-day public comment 

period [79 FR 45803]. EPA intends to grant this request at the close of the comment period 

unless the Agency receives substantive comments within the comment period that would merit 

its further review of the request, or unless the registrant withdraws their request within this 

period. The Agency anticipates closing the registration review case for tebufenpyrad once all 
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tebufenpyrad product registrations have been cancelled. Pursuant to 40 CFR § 155.42(c), the 

Agency “will close a registration review case if all products in the case are cancelled.” 

If the affected products are not cancelled, the Agency will amend this PWP to reflect potential 

data needs for and the schedule for the registration review.