Exhibit 3.5

                            CERTIFICATE OF CORRECTION
                                       OF
                         CALYPTE BIOMEDICAL CORPORATION

 Pursuant to Section 103(f) of Title 8 of the Delaware Code of 1953, as Amended

         I, the  undersigned,  being  the  Executive  Chairman  of the  Board of
Calypte Biomedical Caorporation,  a corporation organized and existing under and
by virtue of the General  Corporation  Law of the State of  Delaware,  DO HEREBY
CERTIFY:

         RESOLVED, that
         a) In  the  Certificate  of  Amendment  of  the  Amended  and  Restated
Certificate of  Incorporation of this  corporation,  filed with the Secretary of
State on May 22, 2003, within the resolution  setting forth the amendment of the
par value of the Common Stock of the  corporation,  reference to the  resolution
authorizing a reverse stock split was inadvertently and incorrectly omitted, and

         b) In  the  Certificate  of  Amendment  of  the  Amended  and  Restated
Certificate  of  Incorporation  of this  corporation,  the effective date of the
amendment inadvertently was set forth incorrectly, therefore,

         Paragraphs  FIRST and FIFTH of the Amended and Restated  Certificate of
Incorporation should be corrected to read as follows:

         "FIRST:  That  at a  meeting  of the  Board  of  Directors  of  CALYPTE
BIOMEDICAL  CORPORATION,  resolutions  were duly  adopted by  unanimous  written
consent dated March 28, 2003,  setting forth a proposed amendment of the Amended
and Restated  Certificate of Incorporation of said  corporation,  declaring said
amendment  to be  advisable  and calling a meeting of the  stockholders  of said
corporation for consideration thereof. The resolution setting forth the proposed
amendment is as follows:

         RESOLVED, that the Amended and Restated Certificate of Incorporation of
this  corporation  be amended by  changing  the first  paragraph  of the Article
thereof  numbered  "IV",  so that,  as  amended,  said  paragraph  shall read as
follows:

<PAGE>

         `IV:
                  The  corporation  is authorized to issue two classes of shares
of stock to be  designated,  respectively,  Common Stock,  $0.03 par value,  and
Preferred  Stock,  $0.001  par  value.  The  total  number  of  shares  that the
corporation is authorized to issue is 805,000,000  shares.  The number of shares
of Common Stock  authorized  is  800,000,000  and the number of Preferred  Stock
authorized is 5,000,000.'

         IT IS FURTHER  RESOLVED  that  CALYPTE  BIOMEDICAL  CORPORATION  be and
hereby is authorized and directed to cause a one for thirty (1:30) reverse stock
split of the issued and  outstanding  Common  Shares,  which reverse stock split
shall  decrease the number of issued and  outstanding  shares of Common Stock by
one-thirtieth,  but shall have no effect on the 800,000,000 shares of authorized
Common Stock."

         "FIFTH:  That said amendment shall become effective on May 28, 2003."

         IN WITNESS WHEREOF,  I have hereunto set my hand and seal this 27th day
of May, 2003

/s/ Anthony J. Cataldo
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Anthony J. Cataldo
Executive Chairman of the Board