Exhibit 10.90





CALYPTE
BIOMEDICAL CORPORATION


1265 Harbor Bay Parkway


Alameda, CA 94502





December 19, 2001





David Collins


PMB # 224


774 Mays Blvd., # 10


Incline Village, NV 89451





Re:    Consulting Agreement With Calypte





Dear Dave:





Upon your signature at the end of this letter where indicated, this letter will be
the binding agreement (the Agreement), effective as of October 19, 2001 (the Effective Date), between Calypte Biomedical Corporation (Calypte) and you with respect to your provision of service
as a consultant to Calypte as provided in this letter. The Basic Retained Services described in Section 1(a) hereof and any Additional Services defined in Section 1(b) hereof are referred to herein collectively as the Services.





1.    Services.





(a)  Basic Retained Services.    Subject to the terms and conditions of this Agreement, you hereby are retained by Calypte as a
consultant to Calypte from the Effective Date until terminated as provided herein, to provide (i) an aggregate of five (5) days of Services (the Basic Retained Services) per calendar month during the term hereof, commencing with
the month of October, 2001 (with a day of Services being considered for such purposes as eight (8) hours, with travel time while on business for Calypte, and while travelling from your home outside of California to Calyptes
principal offices for purposes of rendering such Basic Retained Services, in each case being counted as one-half time), and (ii) such additional days of Additional Services, as provided in and defined in Section 1(b) hereof, as you may agree with
Calypte upon Calyptes reasonable and good faith request to you, in each case with respect to Calyptes business, and such other matters commensurate with the position of Chairman of the Board, all as may be requested from time to time
during the term hereof orally or in writing by the Board of Directors (the Board) of Calypte or by the Chief Executive Officer of Calypte.





(b)  Additional Services.    In addition to the Basic Retained Services rendered as described in Section 1(a) hereof, you will
render such number of days of Services (the Additional Services) as are so requested in good faith by Calypte, by its Board or Chief Executive Officer (with a day of Services being considered for such purposes as eight
(8) hours, with travel time while on business for Calypte, and while travelling from your home outside of California to Calyptes principal offices for purposes of rendering such Basic Retained Services, in each case being counted as one-half
time).





(c)Certain Conditions Concerning Service As A Director Of
Calypte.    You hereby agree that you will serve as the Chairman of the Board for so long as you are duly elected thereto. The number of days you spend rendering Services to Calypte hereunder will be in addition to time you
spend to discharge your customary duties as a Director of Calypte, including time to prepare for and attend meetings of the Board and of Board Committees upon which you serve, during such time as you are serving as a Director of Calypte. Any
compensation you may receive for your services as a Director of Calypte, such as indemnification, stock, and/or stock options and other benefits from the Company as are made available from time to time by the Company to other Directors, will be
separate from this Agreement.







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(d)  Scheduling; Location.    The days upon which Calypte will require your
Services will be based upon dates and times mutually agreeable between you and Calypte. Calypte will provide as much advance notice as possible to you of the dates and times required, and you will make every reasonable effort to make yourself
available during such dates. Calypte will not require you to render such services at dates, times or places that would reasonably interfere with other work commitments you may have. You may render the Services by telephone and/or e-mail, and/or
on-site at Calyptes headquarters in the San Francisco Bay Area, and/or at other locations, as determined in good faith by Calypte after consultation with you as to mutual convenience and the particular Services required.





(e)Reporting.    You will report to the Board, but you will render Services upon the
request of the Board and/or of the Chief Executive Officer of Calypte.





(f)Other
Activities.    Calypte acknowledges and agrees that, while you will devote such time and effort as is necessary to discharge your duties hereunder, you will not be providing your full-time services to Calypte, and that you
may consult with or become an employee of other entities as you wish (including but not limited to accepting full time employment), subject to your obligations as to confidential and proprietary information of Calypte as set forth in this Agreement.





(g)Nonassignability of Your Services.    You may not assign or
subcontract your duties or rights under this Agreement without the prior written consent of Calypte signed by its Chief Executive Officer.





2.    Compensation; Expense Reimbursement; Lodging and Automobile; Stock Options.





(a)  Retainer For Basic Retained Services; Payment For Additional Services.    Calypte will grant you a stock option award for 300,000 shares of its common stock exercisable at
$0.22 per share, under the terms of its 2000 Equity Incentive Plan, (the Stock Option). The Stock Option will be subject to certain restrictions with respect to forfeiture and transferability, as set forth in the Stock Option
documentation that Calypte will provide to you separately from this Agreement. The Stock Option will vest one-twelfth of the optioned shares on each monthly anniversary of the Effective Date over the twelve-month term of this agreement and the Stock
Option will have a ten-year term. In addition, Calypte will pay you a consulting fee in cash for any Additional Services you may render, within thirty (30) days after the close of each calendar month during which you render such Additional Services,
at the rate of one thousand dollars ($1,000.00) per day of such Additional Services.





(b)  Expense Reimbursement; Lodging and Automobile.    Calypte will reimburse you for all reasonable, ordinary and necessary travel and entertainment expenses incurred by you in conjunction with your
services to Calypte hereunder. While you are rendering Services in the San Francisco Bay Area, Calypte will provide lodging for you, or will reimburse you for lodging, in a business hotel or business traveler long-term stay facility reasonably
convenient to Calyptes offices, and will reimburse you for that portion of your automobile lease apportioned for your use of your automobile on business of Calypte. Any such expense, including without limitation lodging or automobile lease
reimbursement will, to the extent not specifically provided in this Section 2(b), be consistent with Calyptes then-standard reimbursement policy, and, as applicable, travel policy, and will be made as to a given expense only if you have
submitted commercially customary support documentation to Calypte therefor.





3.    Our Relationship.





(a)  Independent Contractor.    In performance of your services under
this Agreement, you will be an independent contractor of, and are not an agent or employee of, and have no authority to bind, Calypte by contract or otherwise.





(b)  Employment Taxes and Benefits.    You will report as self-employment income all compensation you received pursuant to this
Agreement, including the fair market value of the Shares. You will indemnify Calypte and hold it harmless from and against all claims, damages, losses and expenses, relating to any obligation imposed by law on Calypte to pay any withholding taxes,
social security (except for employers share of social security, if any), unemployment or disability insurance, or similar items in connection with compensation received by you pursuant to this Agreement. You will not be entitled to receive any
vacation




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or illness payments, or to participate in any plans, arrangements, or distributions by Calypte pertaining to any bonus, stock option, profit sharing, insurance or similar benefits for
Calyptes employees, except as provided herein or as otherwise specifically approved by the Board.





(c)  No Remuneration as to Products.    You will receive no royalty or other remuneration on the production or distribution of any products developed by the Company or by you in connection with or based
upon the Services.





4.    Indemnification.





(a)  By You.    To the extent determined by a tribunal of competent jurisdiction (arbitral or judicial), not subject to further
appeal, you will indemnify Calypte and hold it harmless from and against all claims, damages, losses and expenses, including court costs and reasonable fees and expenses of attorneys, expert witnesses, and other professionals, arising out of or
resulting from:





(i)  Any action by a third party against Calypte to the extent based on any claim
that any Services performed under this Agreement, or their results, to your actual knowledge (A) infringe a patent, trademark, copyright or other proprietary right, and/or (B) violate a trade secret of such third party; and





(ii)  Any action by a third party to the extent based on any conduct by you in performing Services under this Agreement
which results in any of the following and for which such tribunal determines you to be liable to Calypte under applicable law: (A) any bodily injury, sickness, disease or death; (B) any injury or destruction to tangible or intangible property
(including computer programs and data) or any loss of use resulting therefrom; or (C) any violation of any statute, ordinance, or regulation.





(b)  By Calypte.    To the extent legally permitted, and not in derogation of your obligations under Section 4(a) hereof: (i) you will be considered as subject to the indemnity
provisions of Calyptes Certificate of Incorporation and Bylaws, a copy of which will be furnished to you upon request, and (ii) Calypte will indemnify you and hold you harmless from and against all claims, damages, losses and expenses,
including court costs and reasonable fees and expenses of attorneys, expert witnesses, and other professionals, arising out of or resulting from any action by a third party against Calypte or you, or both, in connection with or based upon the
performance by you of the Services, or their result.





5.    Property of Calypte.





(a)  Definitions.    For the purposes of this Agreement:





(i)  Inventions means any and all inventions, ideas, designs, circuits, schematics, formulas, algorithms,
trade secrets, works of authorship, mask works, developments, methods, processes, techniques, improvements, and related know-how in the field of research, development and commercialization in which Calypte is engaged, and which are made by you,
alone or in combination with others, which result from or relate to the services you perform for Calypte hereunder, and whether made on behalf of Calypte under this Agreement, or with the use of or as a result of access to Confidential Information,
including but not limited to any derivative work which constitutes an improvement or modification to any tangible form of Confidential Information, as hereinafter defined, such as any design, drawing, or product that embodies Confidential
Information.





(ii)  Designs and Materials means all designs, discoveries,
inventions, products, computer programs, procedures, improvements, developments, drawings, notes, documents, information and materials made, conceived or developed by you alone or with others which result from or relate to the services you perform
for Calypte hereunder.





(iii)  Moral Rights means any right to claim authorship
of a work, any right to object to any distortion or other modification of a work, and any similar right, existing under the law of any country in the world, or under any treaty.





(b)  Assignment of Ownership.    You agree that all the Inventions, Designs and Materials that (1) are developed using equipment,
supplies, facilities or trade secrets of Calypte, (2) result from work performed by you for Calypte or (3) relate to Calyptes business or current or anticipated research and development,




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will be the sole and exclusive property of Calypte. You hereby irrevocably transfer and assign any and all of your right, title, and interest in and to Inventions, Designs and Materials,
including but not limited to all patent rights, copyrights, trademarks and trade secrets, to Calypte. All Inventions, Designs and Materials will be the sole property of Calypte and Calypte will have the sole right to determine the treatment of any
Inventions, Designs and Materials, including the right to keep them as trade secrets, to file and execute patent applications on them, to use and disclose them without prior patent application, to file registrations for copyright or trademark on
them in its own name, or to follow any other procedure that Calypte deems appropriate. You acknowledge that copyrightable works prepared by you within the scope of your service hereunder are works for hire under the federal Copyright Act
and that Calypte will be considered the author thereof. If Calypte files an original United States patent application covering any invention of which you are a named inventor, you will receive in each case from Calypte an inventors fee of One
Hundred Dollars $100.00 in cash as full compensation therefor. You will:





(i)  Disclose promptly in
writing to Calypte all Inventions, Designs and Materials; and





(ii)  Cooperate with and assist
Calypte to apply for, and to execute any applications and/or assignments reasonably necessary to obtain, any patent, copyright, trademark or other statutory protection for Inventions, Designs and Materials in Calyptes name as Calypte deems
appropriate, provided that Calypte will reimburse you for any reasonable costs incurred by you, and your normal billing rate for reasonable time incurred, in connection therewith; and





(iii)  Otherwise treat all Inventions, Designs and Materials as Confidential Information, as defined below. Your obligations to so disclose,
assist, and execute will survive until the earlier of your death or disability or five years following any expiration or termination of this Agreement.





(c)  Moral Rights Waiver.    You hereby irrevocably transfer and assign to Calypte any and all Moral Rights that you may have in
any services you render hereunder, or in any Inventions, Designs and Materials or products of Calypte. You also hereby forever waive and agree never to assert against Calypte, its successors or licensees any and all Moral Rights you may have in any
such services, Inventions, Designs and Materials or such products, even after expiration or termination of this Agreement.





(d)  Company Property.    All papers, records, data, notes, drawings, files, documents, samples, devices, products, equipment, and other materials, including copies and in whatever
form, relating to the business of Calypte that you possess or create as a result of your service to Calypte, whether or not confidential, are the sole and exclusive property of Calypte.





6.    Confidential Information.    You acknowledge that you will acquire information and materials from Calypte and knowledge about the
business, products, programming techniques, experimental work, customers, clients and suppliers of Calypte and that all such knowledge, information and materials acquired, the existence, terms and conditions of this Agreement, and the Designs and
Materials, are and will be the trade secrets and confidential and proprietary information of Calypte (collectively Confidential Information). Confidential Information will not include, however, any information which is or becomes
part of the public domain through no fault of your own or that Calypte regularly gives to third parties without restriction on use or disclosure. You will hold all such Confidential Information in strict confidence, and will not disclose it to
others or use it in any way, commercially or otherwise, except in performing your services hereunder, and will not allow any unauthorized person access to it, either before or after expiration or termination of this Agreement. You will take all
action reasonably necessary and satisfactory to protect the confidentiality of the Confidential Information in your possession, including, without limitation, implementing and enforcing operating procedures to minimize the possibility of
unauthorized use or copying of the Confidential Information.





7.    Term of Service; Termination; Effect
of Termination.





(a)  Term of Service.    This Agreement is for a
period of twelve (12) months from and after the Effective Date, subject to earlier termination as provided in Section 7(b) hereof.




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(b)  Termination; Effect of Termination.





(i)Termination.    This Agreement will terminate automatically upon the earliest of
(A) your death, (B) such date as you voluntary terminate service, by written notice to Calypte, or (C) the date upon which Calypte terminates your service hereunder for cause by giving written notice thereof to you, stating therein that such
termination is for cause and specifying in reasonable detail such cause, or (D) the date upon which your successor as Chairman of the Board of Calypte has been appointed. For purposes of this Agreement, cause is defined as your willful
failure to follow lawful and commercially reasonable directives of the Board, and/or intentional damage to the tangible or intangible property of Calypte, and/or conviction of a crime involving moral turpitude, and/or the performance of any
dishonest or fraudulent act which is or would be, in each case as determined in good faith by the Board, materially detrimental to the interest of Calypte and its other stockholders.





(ii)  Effect of Termination.    Upon termination of your service with Calypte hereunder for any reason, Calypte will pay you all of
your accrued and unpaid expenses, if any, provided, as to a given expense, you have submitted commercially customary support documentation to Calypte therefor. Your obligations of confidentiality hereunder will survive any such termination, and
termination hereof will not have any effect on any other binding agreement between Calypte and you except to the extent specifically so stated in such other agreement or agreements. Your termination hereunder will not be deemed to be a termination
of all your services with Calypte, for purposes of your Option, if you then are still serving Calypte as a consultant, including service as a Director.





8.    Prior Contracts.    You represent that except as disclosed in writing to Calypte, (a) there are no other contracts to assign Inventions, Designs or Materials that
are, as of the Effective Date, in existence between you and any other person or entity, and (b) as of the Effective Date, you have no employment, consultancies or undertakings which would restrict or impair your performance of this Agreement.





9.    General.    This Agreement may be executed in counterparts, each of which
will be deemed an original, but both of which together will constitute one and the same instrument. This Agreement will be governed by the laws of the State of California without regard to its body of law controlling conflict of laws. This Agreement
is the complete and exclusive agreement between you and Calypte regarding the specific subject matter of this Agreement, which subject matter relates solely to your rendering of services to Calypte as a consultant in the position of Chairman of the
Board of Calypte, and not to any other binding agreement you may have with Calypte nor with respect to your service as a Director of Calypte, and supersedes in their entirety all prior agreements, understandings and communications, oral or written,
between us regarding such specific described subject matter. This Agreement will be binding upon and inure to our respective successors and assigns, and upon your heirs, executors and administrators, and may only be amended by a writing signed by
each of us or our respective successors, assigns or authorized representatives.




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We look forward to continuing to work with you, Dave, as part of our team for the success of
Calypte.





| | Sin | cerely,
| | --- | -------




| | /s/    NANCY E. KATZ
| | --------------------

| | 
| | 

| | Nancy E. Katz
| | -------------

| | President and Chief Executive Officer
| | -------------------------------------




ACCEPTED AND AGREED:





/s/    DAVID E. COLLINS


_____________________________________________


David Collins


Date:    December 19, 2001