Exhibit 31.1

  CERTIFICATION OF THE REGISTRANT'S PRINCIPAL EXECUTIVE OFFICER
PURSUANT TO RULE 13A-14(A) OF THE SECURITIES EXCHANGE ACT OF 1934,
                 AS AMENDED, AS ADOPTED PURSUANT TO
            SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Stephen F. Hiu, certify that:

  1.  I have reviewed this quarterly report on Form 10-Q of IGENE
  Biotechnology, Inc. (the "Registrant");

  2.  Based  on  my  knowledge, this report does not contain  any
  untrue statement of a material fact or omit to state a material
  fact  necessary to make the statements made, in  light  of  the
  circumstances  under  which  such  statements  were  made,  not
  misleading with respect to the period covered by this report;

  3.  Based  on my knowledge, the financial statements, and other
  financial  information  included in this report, fairly present
  in  all  material  respects the financial condition, results of
  operations and cash flows of the Registrant as of, and for, the
  periods presented in this report;

  4.    The  Registrant's other certifying officer(s) and  I  are
  responsible   for   establishing   and  maintaining  disclosure
  controls  and  procedures  (as  defined  in  Exchange Act Rules
  13a-15(e) and  15d-15(e))  and  internal control over financial
  reporting  (as  defined  in  Exchange  Act  Rules 13a-15(f) and
  15d-15(f) for the Registrant and have:

          a.   Designed  such disclosure controls and procedures,
          or caused such disclosure controls and procedures to be
          designed under our supervision, to ensure that material
          information  relating to the Registrant, including  its
          consolidated  subsidiaries, is  made  known  to  us  by
          others  within those entities, particularly during  the
          period in which this report is being prepared;

          b.   Designed  such  internal  control  over  financial
          reporting,   or  caused  such  internal  control   over
          financial   reporting   to  be   designed   under   our
          supervision, to provide reasonable assurance  regarding
          the   reliability  of  financial  reporting   and   the
          preparation   of  financial  statements  for   external
          purposes   in   accordance  with   generally   accepted
          accounting principles;

          c.   Evaluated  the  effectiveness of the  Registrant's
          disclosure  controls and procedures  and  presented  in
          this report our conclusions about the effectiveness  of
          the  disclosure controls and procedures, as of the  end
          of  the  period  covered by this report based  on  such
          evaluation; and

          d.    Disclosed  in  this  report  any  change  in  the
          Registrant's internal control over financial  reporting
          that  occurred  during  the  Registrant's  most  recent
          fiscal  quarter (the Registrant's fourth fiscal quarter
          in  the  case of an annual report) that has  materially
          affected, or is reasonably likely to materially affect,
          the   Registrant's  internal  control  over   financial
          reporting; and

  5.    The  Registrant's other certifying officer(s) and I  have
  disclosed,  based  on  our most recent evaluation  of  internal
  control  over financial reporting, to the Registrant's auditors
  and  the audit committee of the Registrant's board of directors
  (or persons performing the equivalent functions):

          a.    All   significant   deficiencies   and   material
          weaknesses  in  the  design or  operation  of  internal
          control  over financial reporting which are  reasonably
          likely to adversely affect the Registrant's ability  to
          record,   process,   summarize  and  report   financial
          information; and

          b.  Any  fraud, whether or not material, that  involves
          management  or  other employees who have a  significant
          role   in   the  Registrant's  internal  control   over
          financial reporting.

Date: May 15, 2009

/S/ STEPHEN F. HIU
____________________
    Stephen F. Hiu
    President