48280 Federal Register / Vol. 74, No. 182 / Tuesday, September 22, 2009 / Notices 

for biocontainment practices for loose 

housed animals. 

Appendix G–II–C–5–c. Occupational 

Health 

A detailed occupational health plan 

shall be developed in advance of 

working with these agents in 

consultation, as needed, with 

individuals with the appropriate 

clinical expertise. In addition, the 

appropriate public health authority 

shall be consulted (e.g. local public 

health officials) on the plan and a mock 

drill of this plan shall be undertaken 

periodically. The plan should include 

an incident reporting system and 

laboratory workers shall report all 

incidents. 

Appendix G–II–C–5–c–(1). Laboratory 

workers shall be provided with medical 

cards which include, at a minimum, the 

following information: characterization 

of the influenza virus to which they 

have been potentially exposed, and 24- 

hour contact numbers for the principal 

investigator and institution’s 

occupational health care provider(s). 

Appendix G–II–C–5–c–(2). A detailed 

occupational health plan shall include: 

(1) Unless there is a medical 

contraindication to vaccination (e.g. 

severe egg allergy) annual seasonal 

influenza vaccination as prerequisite for 

research to reduce risk of influenza like 

illness requiring isolation and tests to 

rule out infection with experimental 

virus and possible co-infection with 

circulating influenza strains. 

(2) Virus specific vaccination, if 

available, should be offered; 

(3) Reporting of all respiratory 

symptoms and/or fever (i.e. influenza 

like illnesses); and 

(4) 24-hour access to a medical facility 

that is prepared to implement 

appropriate respiratory isolation to 

prevent transmission and is able to 

provide appropriate antiviral agents. 

Real-time reverse transcriptionpolymerase chain reaction (RT–PCR) 

procedures should be used to 

discriminate these viruses from 

currently circulating human influenza 

viruses. For exposures to viruses 

containing genes from 1918 H1N1 or the 

HA gene from human H2N2 (1957– 

1968), specimens shall be sent to the 

CDC for testing (RT–PCR and 

confirmatory sequencing). 

Appendix G–II–C–5–c–(3). In 

preparing to perform research with 1918 

H1N1, human H2N2 (1957–1968), or 

HPAI H5N1, principal investigators 

should develop a clear plan specifying 

who will be contacted in the event of a 

potential exposure (during and after 

work hours) to conduct a risk 

assessment and make decisions as to the 

required response, including the need 

for and extent of isolation of the 

exposed worker. After any kind of 

potential exposure, a rapid risk 

assessment shall be performed by the 

principal investigator, health and 

biosafety officials and subsequent 

actions should depend on the appraised 

level of risk of respiratory infection for 

the individual and potential for 

transmission to others. A laboratory 

worker performing research with either 

an influenza virus containing the HA 

gene from human H2N2 or an influenza 

virus containing genes and/or segments 

from 1918 H1N1, shall be informed in 

advance that, in the case of a known 

laboratory exposure with a high risk for 

infection, e.g., involving the upper or 

lower respiratory tract or mucous 

membranes, the laboratory worker will 

need to be isolated in a predetermined 

facility, rather than home isolation, 

until infection can be ruled out by 

testing (e.g., negative RT–PCR for 1918 

H1N1 or human H2N2 (1957–1968)) of 

appropriately timed specimens. 

Laboratory workers shall be informed in 

advance that in the case of a known 

laboratory exposure to highly 

pathogenic avian influenza H5N1 

strains within the Goose/Guangdong/96- 

like H5 lineage with high risk for 

infection, they should be prepared to 

self isolate (for example at home) until 

infection can be ruled out by testing 

(e.g., negative RT–PCR for HPAI H5N1) 

of appropriately timed specimens. The 

action taken for other types of exposures 

should be based on the risk assessment. 

In addition, based on the risk 

assessment: (1) Treatment with 

appropriate antiviral agents shall be 

initiated, and (2) the appropriate public 

health authorities shall be notified. 

Appendix G–II–C–5–c–(4). Influenzalike illness. If a laboratory worker, who 

had recent exposure (within ten days) to 

influenza viruses containing the human 

H2N2 HA gene or any gene from the 

1918 H1N1 or HPAI H5N1 viruses, or to 

animals exposed to such viruses, 

demonstrates symptoms and/or signs of 

influenza infection (e.g., fever/chills, 

cough, myalgias, headache), then the lab 

worker shall report by phone to the 

supervisor/principal investigator and 

other individuals identified in the 

occupational health plan. The 

laboratory worker shall be transported 

to a healthcare facility that can provide 

adequate respiratory isolation, 

appropriate medical therapy, and testing 

to determine whether the infection is 

due to a recombinant influenza virus. 

The appropriate public health 

authorities shall be informed whenever 

a suspected case is isolated. 

Appendix G–II–C–5–c–(5). For 1918 

H1N1 research, the use of antiviral 

agents (e.g., oseltamivir) for preexposure prophylaxis shall be discussed 

with laboratory workers in advance 

including a discussion of the data on the 

safety of long term exposure to these 

agents and their ability to reduce the 

risk of clinical disease and the limits of 

the data regarding protection of close 

contacts and the community. 

Appendix G–II–C–5–c–(6). Antiviral 

agents for post-exposure prophylaxis 

shall be provided only after medical 

evaluation. Home supplies shall not be 

provided in advance for research with 

1918 H1N1 or influenza viruses 

containing the HA gene from human 

H2N2. 

Dated: September 15, 2009. 

Jacqueline Corrigan-Curay, 

Acting Director, Office of Biotechnology 

Activities, National Institutes of Health. 

[FR Doc. E9–22693 Filed 9–21–09; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

U.S. Customs and Border Protection 

Agency Information Collection 

Activities: Application To Establish a 

Centralized Examination Station 

AGENCY: U.S. Customs and Border 

Protection (CBP), Department of 

Homeland Security. 

ACTION: 60-Day notice and request for 

comments; Extension of an existing 

collection of information: 1651–0061. 

SUMMARY: As part of its continuing effort 

to reduce paperwork and respondent 

burden, CBP invites the general public 

and other Federal agencies to comment 

on an information collection 

requirement concerning the Application 

to Establish a Centralized Examination 

Station (CES). This request for comment 

is being made pursuant to the 

Paperwork Reduction Act of 1995 (Pub. 

L. 104–13; 44 U.S.C. 3505(c)(2)). 

DATES: Written comments should be 

received on or before November 23, 

2009, to be assured of consideration. 

ADDRESSES: Direct all written comments 

to U.S. Customs and Border Protection, 

Attn: Tracey Denning, Office of 

Regulations and Rulings, 799 9th Street, 

NW., 7th Floor, Washington, DC 20229– 

1177. 

FOR FURTHER INFORMATION CONTACT: 

Requests for additional information 

should be directed to Tracey Denning, 

U.S. Customs and Border Protection, 

Office of Regulations and Rulings, 799 


sroberts on DSKD5P82C1PROD with NOTICES
Federal Register / Vol. 74, No. 182 / Tuesday, September 22, 2009 / Notices 48281 

9th Street, NW., 7th Floor, Washington, 

DC 20229–1177, at 202–325–0265. 

SUPPLEMENTARY INFORMATION: CBP 

invites the general public and other 

Federal agencies to comment on 

proposed and/or continuing information 

collections pursuant to the Paperwork 

Reduction Act of 1995 (Pub. L. 104–13; 

44 U.S.C. 3505(c)(2)). The comments 

should address: (a) Whether the 

collection of information is necessary 

for the proper performance of the 

functions of the agency, including 

whether the information shall have 

practical utility; (b) the accuracy of the 

agency’s estimates of the burden of the 

collection of information; (c) ways to 

enhance the quality, utility, and clarity 

of the information to be collected; (d) 

ways to minimize the burden including 

the use of automated collection 

techniques or the use of other forms of 

information technology; and (e) the 

annual costs burden to respondents or 

record keepers from the collection of 

information (a total capital/startup costs 

and operations and maintenance costs). 

The comments that are submitted will 

be summarized and included in the CBP 

request for Office of Management and 

Budget (OMB) approval. All comments 

will become a matter of public record. 

In this document CBP is soliciting 

comments concerning the following 

information collection: 

Title: Application to Establish 

Centralized Examination Station. 

OMB Number: 1651–0061. 

Form Number: None. 

Abstract: If a port director decides his 

or her port needs a Centralized 

Examination Station (CES), the port 

director announces this need to the 

public and solicits applications to 

operate a CES. The information 

contained in the application will be 

used to determine the suitability of the 

applicant’s facility, the fairness of his 

fee structure, his knowledge of cargo 

handling operations and his knowledge 

of CBP procedures. 

Current Actions: There are no changes 

to the information collection. This 

submission is being made to extend the 

expiration date. 

Type of Review: Extension (without 

change). 

Affected Public: Businesses. 

Estimated Number of Respondents: 

50. 

Estimated Number of Annual 

Responses per Respondent: 1. 

Estimated Time per Response: 2 

hours. 

Estimated Total Annual Burden 

Hours: 100. 

Dated: September 16, 2009. 

Tracey Denning, 

Agency Clearance Officer, Customs and 

Border Protection. 

[FR Doc. E9–22740 Filed 9–21–09; 8:45 am] 

BILLING CODE 9111–14–P 

DEPARTMENT OF THE INTERIOR 

U.S. Geological Survey 

Agency Information Collection 

Activities: Comment Request 

AGENCY: U.S. Geological Survey (USGS), 

Interior. 

ACTION: Notice of an extension of an 

information collection (1028–0051). 

SUMMARY: To comply with the 

Paperwork Reduction Act of 1995 

(PRA), we are notifying the public that 

we will submit to OMB an information 

collection request (ICR) to renew 

approval of the paperwork requirements 

for respondents to submit proposals to 

support research in earthquake hazard 

assessments and earthquake occurrence 

under the Earthquake Hazards 

Reduction Act of 1977, as amended, 

Public Law 95–124, 42 U.S.C. 7701 et 

seq. To submit a proposal three standard 

OMB forms and a project narrative must 

be completed and submitted via 

Grants.gov. This notice provides the 

public an opportunity to comment on 

the paperwork burden of these forms. 

DATES: You must submit comments on 

or before November 23, 2009. 

ADDRESSES: Send your comments on 

this information collection directly to 

the Office of Management and Budget 

(OMB), Office of Information and 

Regulatory Affairs, Attention: Desk 

Officer for the Department of the 

Interior via OMB e-mail: 

(OIRA_DOCKET@omb.eop.gov); or by 

fax (202) 395–6566; and identify your 

submission with Information Collection 

Number 1028–0051 in the subject line. 

Please submit a copy of your comments 

to Phadrea Ponds, Information 

Collections, U.S. Geological Survey, 

2150–C Center Avenue, Fort Collins, CO 

80525 (mail); (970) 226–9230 (fax); or 

FAX: pponds@usgs.gov (e-mail). Use 

Information Collection Number 1028– 

0051 in the subject line. 

FOR FURTHER INFORMATION CONTACT: To 

request additional information about 

this ICR, Elizabeth Lemersal, Earthquake 

Hazards Program, (703) 648–6716. 

SUPPLEMENTARY INFORMATION: 

Title: Earthquake Hazards Program 

Research and Monitoring. 

OMB Control Number: 1028–0051. 

Type of Request: Extension of a 

currently approved collection. 

Abstract: Research and monitoring 

findings are essential to fulfilling 

USGS’s responsibility under the 

Earthquake Hazards Reduction Act to 

develop earthquake hazard assessments 

and recording and reporting earthquake 

activity nationwide. Residents, 

emergency responders, and engineers 

rely on the USGS for this accurate and 

scientifically sound information. 

Respondents to Program 

Announcements submit proposals to 

support research and monitoring related 

to earthquake hazard assessments, 

earthquake causes and effects, and 

earthquake monitoring. This 

information is used as the basis for 

selection and award of projects meeting 

the USGS’s Earthquake Hazards 

Program objectives. Final reports of 

research and monitoring findings are 

required for each funded proposal; 

annual progress reports are required for 

awards of a two- to five-year duration. 

Final reports are made available to the 

public at the Web site http:// 

earthquake.usgs.gov/research/external/. 

We will protect information from 

respondents considered proprietary 

under the Freedom of Information Act 

(5 U.S.C. 552) and implementing 

regulations (43 CFR Part 2), and under 

regulations at 30 CFR 250.197, ‘‘Data 

and information to be made available to 

the public or for limited inspection.’’ 

Responses are voluntary. No questions 

of a ‘‘sensitive’’ nature are asked. 

Affected Public: Research scientists, 

engineers, and the general public. 

Respondent Obligation: Voluntary; 

necessary to receive benefits. 

Frequency of Collection: Annually 

and once every three to five years. 

Estimated Annual Number of and 

Description of Respondents: 250 

Educational institutions, and profit and 

non-profit organizations. 

Estimated Annual Number of 

Responses: 370 (250 applications and 

narratives and 120 annual and final 

report). 

Estimated Completion Time: 45 hours 

per application response and 9 hours 

per final report. 

Estimated Annual Burden Hours: 

12,330 (11,250 hours per application 

and 1,080 hours per annual and final 

report). 

Estimated Annual Reporting and 

Recordkeeping ‘‘Hour’’ Burden: We 

estimate the public reporting burden 

will average 45 hours per application 

response. This includes time to develop 

project goals, write the statement of 

work, perform internal proposal 

reviews, and submit the proposal 

through grants.gov. We estimate the 

public reporting burden will average 9 

hours per final or annual report 


sroberts on DSKD5P82C1PROD with NOTICES