**EXHIBIT 21**

 

**LIST OFSUBSIDIARIES OF CHIRON CORPORATION**

 
| **SUBSIDIARY**                                                                                                                | ** ** | **JURISDICTION OF INCORPORATION  OR ORGANIZATION** |
|-------------------------------------------------------------------------------------------------------------------------------|------------|----------------------------------------------------|
|                                                                                                                          |       |                                               |
| Cetus Generic  Corporation                                                                                                    |       | Delaware, USA                                      |
| Chiron Partners, Inc.                                                                                                         |       | California, USA                                    |
| Chiron Alpha  Corporation                                                                                                     |       | California, USA                                    |
| Chiron/Cephalon JV  (50%)                                                                                                     |       | Delaware, USA                                      |
| Chiron Properties, Inc.                                                                                                       |       | California, USA                                    |
| Chiron Delta  Corporation                                                                                                     |       | Delaware, USA                                      |
| Chiron Investment  Corporation                                                                                                |       | Nevada, USA                                        |
| Chiron Mimotopes U.S.                                                                                                         |       | California, USA                                    |
| Chiron Redevelopment  Corporation                                                                                             |       | Missouri, USA                                      |
| Chiron Foreign Sales  Corporation                                                                                             |       | U.S. Virgin Islands                                |
| Biocent Insurance  Company, Inc.                                                                                              |       | Hawaii, USA                                        |
| Chiron AB                                                                                                                     |       | Sweden                                             |
| Chiron Behring Vaccines  Private Limited (51%)                                                                                |       | India                                              |
| Chiron Technologies  Pty. Ltd.                                                                                                |       | Australia                                          |
| Chiron B-1 Limited  (formerly known as “Chiron IL-2 Technology (Bermuda) Ltd.”, name changed  effective 12/6/01)(1) |       | Bermuda                                            |
| Chiron Overseas Holding  Co.                                                                                                  |       | Nevada, USA                                        |
| Sagres Discovery, Inc.                                                                                                        |       | Delaware, USA                                      |
| MemRex  Corporation                                                                                                           |       | Delaware, USA                                      |
| Prion Solutions, Inc.                                                                                                         |       | California, USA                                    |
| Chiron  B-2 Limited (1)                                                                                                       |       | Bermuda                                            |
| Chiron  Blood Testing (Bermuda) Ltd.                                                                                          |       | Bermuda                                            |
| Chiron  Vaccines LLC                                                                                                          |       | Delaware, USA                                      |
| Chiron  B.V.                                                                                                                  |       | The Netherlands                                    |
| Chiron  Blood Testing B.V.                                                                                                    |       | The Netherlands                                    |
| AlgoRx  Pharmaceuticals Inc. US (13%)                                                                                         |       | Delaware, USA                                      |
| Bavarian Nordic AS (6%)                                                                                                       |       | Denmark                                            |
| Chiron  Canada ULC/Chiron Canada SRI                                                                                          |       | Canada                                             |
| Chiron  Blood Testing SAS                                                                                                     |       | France                                             |
| Chiron  Limited                                                                                                               |       | Hong Kong                                          |
| Chiron  Vaccines Holding Limited                                                                                              |       | United Kingdom                                     |
| PowderJect  Pharmaceuticals Limited                                                                                           |       | United Kingdom                                     |
| PowderJect  Pharmaceuticals Employees Share Scheme Trustees Ltd.                                                              |       | Jersey                                             |
| Chiron  Vaccines Limited                                                                                                      |       | United Kingdom                                     |

 

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(1)  Chiron B-1 Limited andChiron B-2 Limited entered into a partnership called Chiron Blood Testing(Bermuda) Ltd. on 12/18/2002; Chiron B-1 holds an 85% partnership interest, andChiron B-2 holds a 15% partnership interest. Together, the 2 entities jointlyown Chiron Blood Testing (Bermuda) Ltd. and the subsidiaries listed thereunder.

 

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| **SUBSIDIARY**                                                                                                                                                                                                                       | ** ** | **JURISDICTION OF INCORPORATION  OR ORGANIZATION** |
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|------------|----------------------------------------------------|
|                                                                                                                                                                                                                                 |       |                                               |
| Chiron  Vaccines Australia Pty Ltd                                                                                                                                                                                                   |       | Australia                                          |
| EPS  Vaccines Limited                                                                                                                                                                                                                |       | United Kingdom                                     |
| PowderChek  Diagnostics Inc.                                                                                                                                                                                                         |       | Delaware, USA                                      |
| Chiron  Healthcare Ireland Limited dba “Chiron Ireland”                                                                                                                                                                    |       | Ireland                                            |
| Chiron  Blood Testing Pty Ltd                                                                                                                                                                                                        |       | Australia                                          |
| PathoGenesis  Portugal –Produtos Farmacêuticos, Sociedade Unipessoal Lda.                                                                                                                                                  |       | Portugal                                           |
| Chiron  Iberia S.L.                                                                                                                                                                                                                  |       | Spain                                              |
| Appold  Consultadoria E Serviços Lda                                                                                                                                                                                            |       | Portugal                                           |
| Chiron  Blood Testing, S.De R.L. de C. V. [Appold-Consultadoria E Servicos (Sociedade  Unipessoal), LDA- 75%;Chiron B.V. – 25%]                                                                                                 |       | Mexico                                             |
| Chiron  Holding LLC (Formerly known as “Chiron LLC”)                                                                                                                                                                       |       | Delaware                                           |
| Chiron  Hungary Üzleti Szolgáltató Korlátolt Felelősségű Társaság (aka  Chiron Hungary Kft.) or Chiron Hungary Business Services Limited Liability  Company (aka Chiron Hungary Ltd)(2) |       | Hungary                                            |
| Chiron  Vaccines Holding Srl (3)                                                                                                                                                                                                     |       | Italy                                              |
| Chiron  Srl                                                                                                                                                                                                                          |       | Italy                                              |
| Istituto  Vaccinogeno Pozzi Srl                                                                                                                                                                                                      |       | Italy                                              |
| Chiron Funding  LLC (0.01%)                                                                                                                                                                                                          |       | Delaware, USA                                      |
| Chiron  Panacea Vaccines Private Limited (50%)                                                                                                                                                                                       |       | India                                              |
| Chiron  Corp. s.r.o. [75%; Chiron Vaccines International & Co KG, 25%]                                                                                                                                                           |       | Czech Republic                                     |
| Chiron  Vacccines International Srl & Co KG                                                                                                                                                                                      |       | Germany                                            |
| 31  Corsa Verwaltungsgesellschaft mbH                                                                                                                                                                                                |       | Germany                                            |
| Chiron  Behring Verwaltungsgesellschaft mbH                                                                                                                                                                                          |       | Germany                                            |
| Chiron  Behring GmbH & Co KG(4)                                                                                                                                                                                                  |       | Germany                                            |
| Chiron  GmbH                                                                                                                                                                                                                         |       | Germany                                            |
| Chiron  Biotecnologia Limitada Brazil(5)                                                                                                                                                                                             |       | Brazil                                             |
| Rocamadour –  Consultadoria e Servicos, Lda (this is an LLC)                                                                                                                                                                    |       | Portugal                                           |
| Chiron  Investment Company Spain, Srl (ETVE)                                                                                                                                                                                         |       | Spain                                              |
| Chiron  Corporation Limited                                                                                                                                                                                                          |       | United Kingdom                                     |
| Chiron Italia  S.r.l                                                                                                                                                                                                                 |       | Italy                                              |
| Chiron France  S.A.S. (formerly S.a.r.l.)                                                                                                                                                                                            |       | France                                             |

 

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(2)  Appold holds a 99.4% interest and ChironHolding LLC holds a 0.6% interest.

(3)  Appold holds a 94% interest and ChironHolding LLC holds a 6% interest.

(4)  Chiron Redevelopment Corp & Co KG holds a99% interest and Chiron Behring holds a 1% interest.

(5)  Members will be: Chiron VaccinesInternational Srl & Co. KG and Chiron Blood Testing (Bermuda) Ltd.

 

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