FORM 10-Q/A
                                (Amendment No. 1)

                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549

(Mark One)

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
ACT OF 1934

For the quarterly period ended March 31, 1999

                                       OR

[  ]TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
ACT OF 1934

For the transition period from ________ to ___________

Commission file number: 0-11749


                                   Scios Inc.

                  State or other jurisdiction of (IRS Employer  incorporation or
                organization Identification No.)

                               Delaware 95-3701481

                                   Scios Inc.
             2450 Bayshore Parkway, Mountain View, California 94040
                                 (415) 940-6656


         Indicate by check mark whether the registrant (1) has filed all reports
required  to be filed by  Section  13 or 15(d) of the  Securities  Exchange  Act
ofv1934  during the  preceding  12 months (or for such  shorter  period that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days. Yes X No ____

         Indicate the number of shares  outstanding of each of the  registrant's
classes of common stock, as of the latest practicable date.

Title                                                        Outstanding

Common Stock, $.001 par value                                38,468,652



<PAGE>



1. The  Consolidated  Statements of Operations and  Comprehensive  Income (Loss)
contained in Part I, Item 1 is hereby  amended in its  entirety by  substituting
the following  Consolidated  Statements of Operations and  Comprehensive  Income
(Loss):


<PAGE>




                                   SCIOS INC.
                                AND SUBSIDIARIES
<TABLE>
<CAPTION>

       Consolidated Statements of Operations and Comprehensive Income (Loss)
                     (In thousands, except share data)


                                                   Three months ended
                                                        March 31,
                                            1999                       1998
                                      ----------------           ---------------
                                                      (Unaudited)
<S>                                           <C>                       <C>
Revenues:
      Product sales                           $7,822                    $8,430
      Co-promotion commissions                 2,728                     1,268
      Research & development contracts         2,177                     4,592
                                      ----------------           ---------------
                                              12,727                    14,290
                                      ----------------           ---------------

Costs and expenses:
      Cost of goods sold                       4,308                     4,805
      Research and development                10,543                    10,527
      Marketing, general and administration    5,313                     4,711
      Profit distribution to third parties     1,117                     1,070
      Restructuring charges                    6,670                        --
                                      ----------------           ---------------
                                              27,951                    21,113
                                      ----------------           ---------------

Loss from operations                         (15,224)                   (6,823)

Other income and expense:
      Investment income                        1,026                       987
      Interest expense                          (670)                     (650)
      Realized gains on securities             4,786                     8,039
      Other income, net                          231                        19
                                      ----------------           ---------------
                                               5,373                     8,395

Equity in net loss of affiliates                   --                     (244)
                                      ----------------           ---------------
      Income (loss) before provision
        for income taxes                     (9,851)                     1,328

Provision for income taxes                       (6)                        (4)
                                      ----------------           ---------------
                                      ----------------           ---------------
      Net Income (loss)                     ($9,857)                    $1,324
                                      ----------------           ---------------

Other comprehensive income (loss):
      Unrealized losses on securities       (10,830)                       (44)
                                      ----------------           ---------------
Comprehensive income (loss)                ($20,687)                    $1,280
                                      ----------------           ---------------

      Earnings (loss) per common share:
           Basic                             ($0.26)                     $0.04
                                      ----------------           ---------------
           Diluted                           ($0.26)                     $0.03
                                      ----------------           ---------------

           Weighted average number
           of common shares outstanding
           used in calculation of:
           Basic                            37,746,605                37,273,536
                                      ----------------           ---------------
                                      ----------------           ---------------
           Diluted                          37,746,605                38,835,221
                                      ----------------           ---------------

The accompanying notes are an integral part of these consolidated financial
statements.
</TABLE>

                                                     2





<PAGE>



                             SIGNATURES



Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned, thereunto duly authorized.

SCIOS INC.


By:___/s/ David W. Gryska_____________________________________________
         David W. Gryska
         Vice President of Finance and CFO
         (Chief Accounting Officer)

Date: July 26, 1999