Exhibit 10.15

        

         

        

        THE SYMBOL “[****]” DENOTES PLACES WHERE CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THE EXHIBIT BECAUSE IT IS BOTH (i) NOT MATERIAL, AND (ii) WOULD LIKELY CAUSE
          COMPETITIVE HARM TO THE COMPANY IF PUBLICLY DISCLOSED

        

        

        SECOND AMENDMENT

         

        TO

         

        LICENSE AGREEMENT

         

        This amendment (“Second Amendment”) to Agreement (defined below) is entered into by and between Sunovion
            Pharmaceuticals Inc. (formerly Cynapsus Therapeutics, Inc.) (“Sunovion”) and Aquestive Therapeutics, Inc. (formerly MonoSol Rx, LLC) (“Aquestive”) and is effective as of October 23, 2020
          (the “Second Amendment Effective Date”). Capitalized terms not defined herein shall have the meaning set forth in the Agreement. Except as set forth in this Second Amendment, all other terms and conditions of the Agreement shall remain in
          full force and effect.

         

        RECITALS

        

        

        WHEREAS, Cynapsus Therapeutics, Inc. developed and owned patented
          technology related to the film based drug delivery of the active pharmaceutical ingredient, Apomorphine;

        

        

        WHEREAS, Aquestive Therapeutics, Inc. owns
          patented and trade secret proprietary technology related to film-based drug delivery systems which includes orally soluble film strips containing active pharmaceutical ingredients;

        

        

        WHEREAS, under the Agreement, Cynapsus Therapeutics, Inc. obtained an
          exclusive right and license from Aquestive Therapeutics, Inc. in connection with the development and commercialization of Apomorphine for oral administration (the “Product”);

        

        

        WHEREAS, Sunovion acquired Cynapsus Therapeutics, Inc. and all rights and licenses to its technology in October of
          2016;

        

        

        WHEREAS, the Parties entered into the First Amendment of the Agreement effective as of March 16, 2020 wherein
          the Parties agreed, among other things, to amend Section 7.2.2(d) of the Agreement to extend the date by which Sunovion may terminate the Agreement upon 180 days prior written notice to March 31, 2028; and

         

        

        

        WHEREAS, the parties to this Second Amendment wish to amend certain terms of that certain License Agreement (as
          amended) entered into by and between Sunovion and Aquestive effective as of April 1, 2016 (the “Agreement”) to clarify certain rights and obligations of the Parties under the Agreement, as outlined below;

         

        NOW, THEREFORE, the parties agree as follows:

        

        

        	

              	1.	
                Section 3.3.2 of the Agreement is deleted in its entirety and replaced with the following:

              


        

        

        “3.3.2

         

        

        
          
            


        

        Subject to  Section 3.4, from January 1, 2025 until the termination of this Agreement, Licensee or its Affiliates, in consideration of the rights granted to Licensee under Section 2.1.1
            and/or 2.1.2, as applicable, shall pay Licensor an amount equal to [****] percent ([****]%) of the quarterly Net Sales of the Product in the Territory, provided that on and after March 31, 2028, in respect of any jurisdiction or jurisdictions
            in the Territory, Licensee may terminate its rights with respect to the Licensed Patents upon one hundred and eighty (180) days prior written notice to Licensor. In such event Licensee or its Affiliates shall cease to be obligated to pay to
            Licensor an amount equal to [****] percent ([****]%) of the quarterly Net Sales of the Product in such jurisdiction or jurisdictions. Licensor will have no further obligations under this Agreement in such jurisdictions where Licensee is not
            paying and/or ceases to pay a royalty on or after March 31, 2028.”

        

        

        	

              	2.	
                Section 8.1.3 is deleted in its entirety and replaced with the following:

              


        

        

        “8.1.3

        

        

        (a) In the event that Licensor desires to abandon or cease prosecution or maintenance of any Licensor Patent in any country in the Territory, Licensor shall provide reasonable prior written notice to
          Licensee of such intention to abandon (“Notice to Abandon”), such Notice to Abandon shall be given no later than sixty (60) days prior to the next deadline for any action that must be taken with respect to any such Licensor Patent in the relevant
          patent office. In such case, upon Licensee’s written election (“Step-In Notice”), provided no later than thirty (30) days after Licensee’s receipt of the applicable Notice to Abandon, Licensee shall have the right to assume prosecution and
          maintenance of such Licensor Patent at Licensee’s expense (“Step-In Rights”).

        

        

        (b) Licensor shall have the right to rescind a Notice to Abandon upon written notification to Licensee no later than ten (10) days after Licensor’s receipt of the applicable Step-In Notice and such
          rescission shall revoke Licensee’s Step-In Rights provided that Licensor within five (5) days of such written notification of rescission shall take all actions necessary to prevent abandonment, cessation of prosecution or maintenance of the
          applicable Licensor Patent at Licensor’s sole expense.

        

        

        (c) Should Licensee fail to provide Step-In Notice within thirty (30) days after Licensee’s receipt of the applicable Notice to Abandon, Licensor may, in its sole discretion, continue prosecution and
          maintenance of such Licensor Patent or discontinue prosecution and maintenance of such Licensor Patent.

        

        

        (d) For clarity, with respect to a Licensor Patent in a country in the Territory, “abandon or cease prosecution or maintenance of any Licensor Patent” as used in this section 8.1.3 shall mean (i) if
          pending, abandon said pending Licensor Patent without having a pending continuing application (e.g., continuation or divisional) on file claiming priority to the pending Licensor Patent to be abandoned in such country, or (ii) if issued, stop
          maintaining said issued Licensor Patent in such country.”

        

        

        [Signatures to follow on next page.]

         

        

        
          
            


        

        IN WITNESS WHEREOF, the parties hereto have caused this Second Amendment to be executed by their duly
          authorized representatives to be effective as of the Second Amendment Effective Date stated above.

        

        

        	
                Sunovion Pharmaceuticals Inc.

              	 	
                Aquestive Therapeutics, Inc.

              
	 	 	 	 	 
	
                By:

              	
                /s/ Yumi Sato

              	 	
                By:

              	
                /s/ Daniel Barber

              


        	 	 	 	 	 
	
                Print Name:

              	
                Yumi Sato

              	 	
                Print Name: 

              	
                Daniel Barber, COO

              


        	 	 	 	 	 
	
                Title:

              	
                EVP, Chief Corporate Strategy Officer

              	 	
                By:

              	
                /s/ Lori Braender

              
	 	 	 	 	 


        	 	 	 	
                Print Name:

              	
                Lori Braender, SVP, General Counsel