EX-4.3





 Exhibit 4.3 

Execution Version 
 SECOND
AMENDMENT TO SECOND AMENDED AND RESTATED 
 MULTICURRENCY MASTER NOTE PURCHASE AGREEMENT 

This SECOND AMENDMENT TO SECOND AMENDED AND RESTATED MULTICURRENCY MASTER NOTE PURCHASE AGREEMENT, dated as of March 5, 2021 (this
“Amendment”), is among Henry Schein, Inc., a Delaware corporation (the “Company”), Metropolitan Life Insurance Company and MetLife Investment Management, LLC (formerly known as MetLife Investment Advisors Company,
LLC and MetLife Investment Advisors, LLC) (together, “MetLife”), and each of the holders of the Existing Notes (as defined below) (together, the “Holders”). 

W I T N E S S E T H 

WHEREAS, reference is made to that certain $200,000,000 Second Amended and Restated Multicurrency Master Note Purchase Agreement, dated as of
June 29, 2018, by and among the Company, MetLife and each Holder party thereto (as amended by that certain First Amendment to Second Amended and Restated Multicurrency Master Note Purchase Agreement, dated as of June 23, 2020, and as may
be further amended, restated, modified or supplemented from time to time, the “Note Facility”) pursuant to which the Company issued and sold to the Holders its (a) 3.42% Series 2017-A Senior
Notes due June 16, 2027 in the original aggregate principal amount of $50,000,000, (b) 3.32% Series 2018-A Senior Notes due January 2, 2028 in the original aggregate principal amount of $50,000,000
and (c) 2.35% Series 2020-A Senior Notes due September 2, 2030 in the original aggregate principal amount of $50,000,000; and 

WHEREAS, the Company has requested, and MetLife and the Holders have agreed, to amend certain terms and conditions of the Note Facility,
subject and pursuant to the terms and conditions of this Amendment; 
 NOW, THEREFORE, in consideration of the premises and mutual covenants
contained herein, the parties hereto agree as follows: 
 SECTION 1. Defined Terms. Unless otherwise defined herein, capitalized
terms used but not defined herein shall have the meanings assigned to such terms in the Note Facility. 
 SECTION 2. Amendments to
the Note Facility. Effective as of the Second Amendment Effective Date, the Note Facility is hereby amended as follows: 
 (a) Subsection
7.2(a) of the Note Facility is hereby amended and restated in its entirety as follows: 
 (a) Covenant Compliance
— (i) the information required in order to establish whether the Company was in compliance with the requirements of Section 10.9 (including reasonably detailed calculations), (ii) a certification by the Senior Financial Officer that the
Company was in compliance with the requirements of Section 10.5(o), Section 10.6(a) and (b)(vi) and Section 10.7(g)(iii) during the quarterly or annual period covered by the statements then being furnished (including with respect to
each such Section, if requested, the calculations of the maximum or minimum amount, ratio or percentage, as the case may be, permissible 












 
under the terms of such Sections, and the calculation of the amount, ratio or percentage then in existence) and (iii) a reconciliation of the treatment of leases which are or would be deemed
by GAAP as in effect on the date hereof to be treated as operating leases, in form and substance reasonably satisfactory to the Required Holders; and 

(b) Subsection 10.9 of the Note Facility is hereby amended and restated in its entirety as follows: 

10.9. Leverage Ratio. The Company will not permit the Consolidated Leverage Ratio to exceed 3.25 to 1.00
for the four fiscal quarters of the Company then last ended (in each case taken as one accounting period) as of the last day of each fiscal quarter; provided, that, to the extent the Company consummates an acquisition permitted by this
Agreement for aggregate cash consideration exceeding $150,000,000 (each, a “Material Acquisition”), the Company may elect, upon written notice to MetLife and each holder of a Note that is an Institutional Investor, which notice
shall be provided no later than the last Business Day of the fiscal quarter in which the relevant Material Acquisition is consummated, to increase the maximum Consolidated Leverage Ratio permitted by this Section 10.9 to 3.75 to 1.00 for the
fiscal quarter in which such Material Acquisition is consummated and the three consecutive fiscal quarters of the Company following such Material Acquisition (each, a “Four Quarter Period”) (retroactive to the first day of such Four
Quarter Period), and the interest rate applicable to the Notes shall increase by 0.50% per annum during the period from (and retroactive to) the first day of such Four Quarter Period until the earlier of (i) the last day of such fiscal quarter
at the end of which the Consolidated Leverage Ratio for the four fiscal quarters of the Company then ended did not exceed 3.25 to 1.00 (retroactive to such date) and (ii) the last day of such Four Quarter Period (each a “Covenant Reset
Date”) (such increase, the “Acquisition Spike”); provided further that, the maximum Consolidated Leverage Ratio may be increased to 3.75 to 1.00 for a Four Quarter Period in connection with a Material
Acquisition no more than three times after the Original Closing Date. For the avoidance of doubt, the Consolidated Leverage Ratio may not exceed 3.25 to 1.00 for the four fiscal quarters of the Company then last ended (in each case taken as one
accounting period) as of the last day of each fiscal quarter that ends after a Covenant Reset Date during a Four Quarter Period. If the Consolidated Leverage Ratio is increased for a Four Quarter Period pursuant to the preceding sentence, no
corresponding increase in the Consolidated Leverage Ratio with respect to a subsequent Material Acquisition may occur until the completion of at least one full fiscal quarter following the last day of such Four Quarter Period. If an interest payment
on any Notes is due after the last day of any fiscal quarter of the Company, but before the Consolidated Leverage Ratio as of such last day has been calculated, then the Company shall pay an amount calculated as if the interest rate in effect on
such last day had continued thereafter. If such calculation shows that there was a change in the interest rate on the Notes effective as of the first day following such last day, then the amount of interest payable by the Company on the next
succeeding interest payment date in respect of such Notes shall be increased or decreased, as applicable, to the extent necessary to reflect the interest rate that should have been taken into account as of such first following day. 

  
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 (c) Section 10 of the Note Facility is hereby amended by deleting Subsection 10.11. 

(d) Schedule B of the Note Facility is hereby amended by: 

(i) amending and restating the definition of “Additional Interest” to read in its entirety as follows: 

“Additional Interest” means the Acquisition Spike. 

(ii) deleting the following definitions: “Cash Equivalents,” “Cost Savings,”
“Consolidated Net Debt,” “Consolidated Net Leverage Ratio,” “Designated Charges,” “Leverage Spike,” “Leverage Spike Period,” “Moody’s,”
“Pro Forma Cost Savings,” “Restricted Payment,” “Restructuring Expenses,” “S&P”, and “Unrestricted Cash.” 

(e) The definition of “Consolidated EBITDA” in Schedule B of the Note Facility is hereby amended and restated in its entirety
as follows: 
 “Consolidated EBITDA” means, for any period, Consolidated Operating Income plus, without
duplication, (a) Consolidated Interest Income, (b) depreciation, (c) amortization, (d) all non-cash charges, (e) to the extent deducted in computing Consolidated Operating Income,
stock-based compensation of the Company and its Subsidiaries, (f) all non-recurring, unusual or extraordinary charges, costs and expenses, and (g) restructuring, consolidation, transaction,
integration or other similar charges and expenses; provided that the aggregate amount under this clause (g) for any applicable period shall not exceed 10% of Consolidated EBITDA for such period, in each case, determined on a consolidated basis
in accordance with GAAP and as calculated consistent with the manner disclosed by the Company in its Annual Report on Form 10-K for the fiscal year ended December 31, 2016. 

SECTION 3. Representations and Warranties. To induce MetLife and the Holders to enter into this Amendment, the Company hereby
represents and warrants to MetLife and the Holders that, both before (except with respect to Section 3(f) below) and after giving effect to this Amendment: 

(a) The Company is a corporation duly organized, validly existing and in good standing under the laws of its jurisdiction of incorporation,
and is duly qualified as a foreign corporation, where legally applicable, and is in good standing in each jurisdiction in which such qualification is required by law, other than those jurisdictions as to which the failure to be so qualified or in
good standing could not, individually or in the aggregate, reasonably be expected to have a Material Adverse Effect. The Company has the corporate power and authority, in all material respects, to own or hold under lease the properties it purports
to own or hold under lease, to transact the business it transacts, to execute and deliver this Amendment and to perform the provisions hereof and thereof. 

  
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 (b) This Amendment has been duly authorized by all necessary corporate action on the part of
the Company, and this Amendment constitutes a legal, valid and binding obligation of the Company enforceable against the Company in accordance with its terms, except as such enforceability may be limited by (i) applicable bankruptcy,
insolvency, reorganization, moratorium or other similar laws affecting the enforcement of creditors’ rights generally and (ii) general principles of equity (regardless of whether such enforceability is considered in a proceeding in equity
or at law). 
 (c) This Amendment and the documents, certificates or other writings delivered to the Holders by or on behalf of the Company
in connection with the amendments set forth herein, taken as a whole, do not contain any untrue statement of a material fact or omit to state any material fact necessary to make the statements therein not misleading in light of the circumstances
under which they were made. There is no fact known to the Company that could reasonably be expected to have a Material Adverse Effect that has not been set forth herein or in the other documents, certificates or other writings delivered to the
Holders by or on behalf of the Company in connection with the amendments set forth herein. 
 (d) No event has occurred and no condition
exists that, either before or after giving effect to this Amendment, constitutes or would constitute a Default or an Event of Default. 

(e) No consent, approval or authorization of, or registration, filing or declaration with, any Governmental Authority is required in
connection with the execution, delivery or performance by the Company of this Amendment. 
 (f) the representations and warranties contained
in the Note Facility (except with respect to Section 5.8, as disclosed in the Company’s Quarterly Report on Form 10-Q or in the Company’s Annual Report on Form
10-K, in each case, most recently filed with the Securities and Exchange Commission) and the other Financing Documents are true and correct in all material respects as of the Second Amendment Effective
Date except to the extent that such representations and warranties specifically refer to an earlier date, in which case they shall be true and correct in all material respects as of such earlier date. 

(g) The Company has not paid, nor has it agreed to pay, any fees or other compensation in connection with the amendments described in
Section 4(b) and (c) below. 
 SECTION 4. Conditions to Effectiveness. The amendments set forth in
Section 2 shall become effective on the first date on which the following conditions precedent have been satisfied or waived (the first date on which such conditions shall have been so satisfied or waived, the
“Second Amendment Effective Date”): 
 (a) the Company, MetLife and the Holders shall have executed and delivered a
counterpart of this Amendment; 
 (b) MetLife and the Holders shall have received a fully executed copy of an amendment agreement to the New
York Life Master Note Facility, dated as of the date hereof (the “New York Life Amendment”), by and among the Company, NYL Investors LLC and the other holders of notes party thereto, in form and substance satisfactory to the
Required Holders; 

  
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 (c) MetLife and the Holders shall have received a fully executed copy of an amendment
agreement to the Prudential Shelf Agreement, dated as of the date hereof (the “Prudential Amendment”), by and among the Company, PGIM, Inc., The Prudential Insurance Company of America and the other holders of notes party thereto,
in form and substance satisfactory to the Required Holders; 
 (d) the 364-Day Facility shall have
been terminated, and the Company shall have provided evidence thereof in form and substance satisfactory to the Required Holders;  

(e) each of the representations and warranties set forth in Section 3 above shall be true and correct as of the date
of the execution and delivery of this Amendment and as of the Second Amendment Effective Date as if made on and as of such date (or if any representation and warranty is expressly stated to have been made as of a specific date, as of such specific
date). 
 (f) no Default or Event of Default shall have occurred and be continuing on and as of the Second Amendment Effective Date or
immediately after giving effect to this Amendment; and 
 (g) the Company shall have paid the reasonable fees and disbursements of the
Holders’ special counsel in accordance with Section 6 below. 
 SECTION 5. Effects on Note
Facility. This Amendment shall be construed in connection with and as a part of the Note Facility and, except as specifically amended herein, the Note Facility shall continue to be in full force and effect and is hereby in all respects ratified
and confirmed. Any and all notices, requests, certificates and other instruments executed and delivered after the execution and delivery of this Amendment may refer to the Note Facility without making specific reference to this Amendment, but
nevertheless all such references shall include this Amendment unless the context otherwise requires. 
 SECTION 6. Expenses.
Without prejudice to the provisions of Section 15 (Expenses, Etc.) of the Note Facility, whether or not the amendments set forth herein become effective, the Company agrees to pay or reimburse MetLife and the Holders for all of their
reasonable and invoiced out-of-pocket costs and expenses incurred in connection with the development, preparation and execution of this Amendment and any other documents
prepared in connection herewith or therewith, and the consummation and administration of the transactions contemplated hereby and thereby, including, without limitation, the reasonble and documented fees and disbursements of Morgan, Lewis &
Bockius LLP, counsel to MetLife and the Holders. 
 SECTION 7. GOVERNING LAW; JURISDICTION AND PROCESS; WAIVER OF JURY TRIAL.
THIS AMENDMENT SHALL BE CONSTRUED AND ENFORCED IN ACCORDANCE WITH, AND THE RIGHTS OF THE PARTIES SHALL BE GOVERNED BY, THE LAW OF THE STATE OF NEW YORK EXCLUDING
CHOICE-OF-LAW PRINCIPLES OF THE LAW OF SUCH STATE THAT WOULD PERMIT THE APPLICATION OF THE LAWS OF A JURISDICTION OTHER THAN SUCH STATE. EACH PARTY HERETO HEREBY AGREES
AS SET FORTH FURTHER IN SECTION 22.8 OF THE NOTE FACILITY AS IF SUCH SECTION WAS SET FORTH IN FULL HEREIN. 

  
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 SECTION 8. No Novation. This Amendment is not intended by the parties to be, and
shall not be construed to be, a novation of the Note Facility or an accord and satisfaction in regard thereto. 
 SECTION 9.
Financing Document. This Amendment shall constitute a “Financing Document” for all purposes of the Note Facility and the other Financing Documents. 

SECTION 10. Amendments; Execution in Counterparts; Electronic Execution. 

(a) This Amendment shall not constitute an amendment of any other provision of the Note Facility not referred to herein and shall not be
construed as a waiver or consent to any further or future action on the part of the Company that would require a waiver or consent of the Holders or MetLife. Except as expressly amended hereby, the provisions of the Note Facility are and shall
remain in full force and effect. 
 (b) This Amendment may be executed in any number of counterparts and by the different parties hereto on
separate counterparts, including by means of facsimile or electronic transmission, each of which when so executed and delivered shall be an original, but all of which shall together constitute one and the same instrument. 

(c) Delivery of an executed counterpart of a signature page of this Amendment by telecopy, emailed pdf. or any other electronic means that
reproduces an image of the actual executed signature page shall be effective as delivery of a manually executed counterpart of this Amendment. The words “execution,” “signed,” “signature,” “delivery,” and
words of like import in or relating to any document to be signed in connection with this Amendment and the transactions contemplated hereby shall be deemed to include an electronic sound, symbol, or process attached to, or associated with, a
contract or other record and adopted by a Person with the intent to sign, authenticate or accept such contract or record (each an “Electronic Signature”), each of which shall be of the same legal effect, validity or enforceability
as a manually executed signature, physical delivery thereof or the use of a paper-based recordkeeping system, as the case may be, to the extent and as provided for in any applicable law, including the Federal Electronic Signatures in Global and
National Commerce Act, the New York State Electronic Signatures and Records Act, or any other similar state laws based on the Uniform Electronic Transactions Act; provided that nothing herein shall require MetLife or the Holders to accept
Electronic Signatures in any form or format without their prior written consent. Without limiting the generality of the foregoing, each party hereto hereby (i) agrees that, for all purposes, including without limitation, in connection with any
workout, restructuring, enforcement of remedies, bankruptcy proceedings or litigation among the MetLife, the Company and the other parties hereto, electronic images of this Amendment or any other Financing Documents (in each case, including with
respect to any signature pages thereto) shall have the same legal effect, validity and enforceability as any paper original, and (ii) waives any argument, defense or right to contest the validity or enforceability of this Amendment or any of
the other Financing Documents based solely on the lack of paper original copies of this Amendment or any other Financing Documents, including with respect to any signature pages hereto or thereto. 

  
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 SECTION 11. Successors and Assigns. All covenants and other agreements contained
in this Amendment by or on behalf of any of the parties hereto bind and inure to the benefit of their respective successors and assigns (including, without limitation, any subsequent holder of a Note) whether so expressed or not. 

SECTION 12. Severability. Any provision of this Amendment that is prohibited or unenforceable in any jurisdiction shall, as to
such jurisdiction, be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining provisions hereof, and any such prohibition or unenforceability in any jurisdiction shall (to the full extent permitted by
law) not invalidate or render unenforceable such provision in any other jurisdiction. 
 [Remainder of page intentionally left blank]


  
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 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly executed and
delivered by their respective proper and duly authorized officers as of the day and year first above written. 
  

					
	HENRY SCHEIN, INC., as the Company
		
	by	 	
		 	 /s/ Michael Amodio

		 	Name:	 	Michael Amodio
		 	Title:	 	Vice President and Treasurer



  
 [Signature Page to
Second Amendment to Second A&R Multicurrency Master Note Purchase Agreement (MetLife)] 













 METLIFE INVESTMENT MANAGEMENT, LLC 

 

					
	 by
	 	
		 	 /s/ John Wills

		 	Name:	 	John Wills
		 	Title:	 	Authorized Signatory

  

	
	METROPOLITAN LIFE INSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	METLIFE INSURANCE K.K.
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	METLIFE REINSURANCE COMPANY OF CHARLESTON
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	FARMERS NEW WORLD LIFE INSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	ZURICH AMERICAN INSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	 PENSION AND SAVINGS COMMITTEE, ON BEHALF OF THE ZURICH AMERICAN

INSURANCE COMPANY MASTER RETIREMENT TRUST

	By: MetLife Investment Management, LLC, Its Investment Manager
	
	ZURICH INSURANCE COMPANY LTD, BERMUDA BRANCH
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	TRANSATLANTIC REINSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	BRIGHTHOUSE LIFE INSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	BRIGHTHOUSE REINSURANCE COMPANY OF DELAWARE
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	AMERICAN FIDELITY ASSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	RSUI Indemnity Company
	By: MetLife Investment Management, LLC, Its Investment Manager


  
 [Signature Page to
Second Amendment to Second A&R Multicurrency Master Note Purchase Agreement (MetLife)] 














	
	METROPOLITAN GROUP PROPERTY AND CASUALTY INSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	ECONOMY FIRE & CASUALTY COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager
	
	SYMETRA LIFE INSURANCE COMPANY
	By: MetLife Investment Management, LLC, Its Investment Manager

  

					
	 by
	 	
		 	 /s/ John Wills

		 	Name:	 	John Wills
		 	Title:	 	Authorized Signatory

 SWISS REINSURANCE COMPANY LIMITED 

By: MetLife Investment Management Limited, Its Investment Manager 
  

					
	 by
	 	
		 	 /s/ Annette Bannister

		 	Name:	 	Annette Bannister
		 	Title:	 	Authorized Signatory


  
 [Signature Page to
Second Amendment to Second A&R Multicurrency Master Note Purchase Agreement (MetLife)]