Form of Registrant's Common Stock Certificate



 Exhibit 4.1 






 
 . 016570| 003590|127C|RESTRICTED||4|057-423 

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COMMON STOCK COMMON STOCK 
 PAR VALUE $0.001 THIS CERTIFICATE IS TRANSFERABLE IN CANTON, MA AND NEW YORK, NY 
 Certificate 
 Shares Number 

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 GLOBEIMMUNE, INC. 

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INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE 

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Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. 
 THIS CERTIFIES THAT 
 MR. SAMPLE & MRS.
SAMPLE & CUSIP 37957B 10 0 
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Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David
Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample ****
Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David
Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. 
 SEE REVERSE FOR
CERTAIN DEFINITIONS 
 MR. SAMPLE & MRS. SAMPLE 

Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample ****
Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Alexander David Sample **** Mr. Sample ****
Mr. Sample 

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 is the owner of 
 ***ZERO HUNDRED THOUSAND 

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 ZERO HUNDRED AND ZERO*** 

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 FULLY-PAID AND NON-ASSESSABLE SHARES OF THE COMMON STOCK OF 
 GlobeImmune, Inc. (hereinafter called the “Company”), transferable on the books of the Company in person or by duly authorized attorney, upon surrender of this Certificate
properly endorsed. This Certificate and the shares represented hereby, are issued and shall be held subject to all of the provisions of the Certificate of Incorporation, as amended, and the By-Laws, as amended, of the Company (copies of which are on
file with the Company and with the Transfer Agent), to all of which each holder, by acceptance hereof, assents. This Certificate is not valid unless countersigned and registered by the Transfer Agent and Registrar. 

Witness the facsimile seal of the Company and the facsimile signatures of its duly authorized officers. 

[GRAPHIC APPEARS HERE] 
  

[GRAPHIC APPEARS HERE] DATED <<Month Day, Year>> 
  
 COUNTERSIGNED AND REGISTERED: 
  
 COMPUTERSHARE TRUST COMPANY, N.A. 
  
 TRANSFER AGENT AND REGISTRAR, 
  
 Chief Executive Officer and President 
  
 [GRAPHIC APPEARS HERE] 

 
 [GRAPHIC APPEARS HERE] 

 
 By 

AUTHORIZED SIGNATURE 







 



 
 GlobeImmune, Inc. THE COMPANY WILL FURNISH WITHOUT CHARGE TO EACH SHAREHOLDER WHO SO
REQUESTS, A SUMMARY OF THE POWERS, DESIGNATIONS, PREFERENCES AND RELATIVE, PARTICIPATING, OPTIONAL OR OTHER SPECIAL RIGHTS OF EACH CLASS OF STOCK OF THE COMPANY AND THE QUALIFICATIONS, LIMITATIONS OR RESTRICTIONS OF SUCH PREFERENCES AND RIGHTS, AND
THE VARIATIONS IN RIGHTS, PREFERENCES AND LIMITATIONS DETERMINED FOR EACH SERIES, WHICH ARE FIXED BY THE CERTIFICATE OF INCORPORATION OF THE COMPANY, AS AMENDED, AND THE RESOLUTIONS OF THE BOARD OF DIRECTORS OF THE COMPANY, AND THE AUTHORITY OF THE
BOARD OF DIRECTORS TO DETERMINE VARIATIONS FOR FUTURE SERIES. SUCH REQUEST MAY BE MADE TO THE OFFICE OF THE SECRETARY OF THE COMPANY OR TO THE TRANSFER AGENT. THE BOARD OF DIRECTORS MAY REQUIRE THE OWNER OF A LOST OR DESTROYED STOCK CERTIFICATE, OR
HIS LEGAL REPRESENTATIVES, TO GIVE THE COMPANY A BOND TO INDEMNIFY IT AND ITS TRANSFER AGENTS AND REGISTRARS AGAINST ANY CLAIM THAT MAY BE MADE AGAINST THEM ON ACCOUNT OF THE ALLEGED LOSS OR DESTRUCTION OF ANY SUCH CERTIFICATE. The following
abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full Additional abbreviations may also be used though not in the above list. PLEASE INSERT SOCIAL SECURITY OR OTHER
IDENTIFYING NUMBER OF ASSIGNEE For value received,             hereby sell, assign and transfer unto (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING POSTAL ZIP CODE, OF ASSIGNEE)
            Shares of the common stock represented by the within Certificate, and do hereby irrevocably constitute and appoint
            Attorney to transfer the said stock on the books of the within-named Company with full power of substitution in the premises. Signature(s) Guaranteed: Medallion Guarantee Stamp
Dated:             20             THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (Banks,
Stockbrokers, Savings and Loan Associations and Credit Unions) WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM, PURSUANT TO S.E.C. RULE 17Ad-15. Signature:             
Signature:              Notice: The signature to this assignment must correspond with the name as written upon the face of the certificate, in every particular, without alteration or
enlargement, or any change whatever. The IRS requires that we report the cost basis of certain shares acquired after January 1, 2011. If your shares were covered by the legislation and you have sold or transferred the shares and requested a
specific cost basis calculation method, we have processed asrequested. If you did not specify a cost basis calculation method, we have defaulted to the first in, first out (FIFO) method. Please visit our website or consult your tax advisor if you
need additional information about cost basis. If you do not keep in contact with us or do not have any activity in your account for the time periods specified by state law, your property could become subject to state unclaimed property laws and
transferred to the appropriate state. according to applicable laws or regulations: TEN COM -as tenants in common UNIF GIFT MIN ACT -.Custodian . (Cust) (Minor) TEN ENT -as tenants by the entireties (State) JT TEN -as joint tenants with right of
survivorship UNIF TRF MIN ACT -.Custodian (until age .) and not as tenants in common (Cust) .under Uniform Transfers to Minors Act . (Minor) (State)