Exhibit 10.3

                                 SECOND WARRANT
                       TO PURCHASE SHARES OF COMMON STOCK
                                       OF
                       PROTEIN POLYMER TECHNOLOGIES, INC.


THE WARRANTS REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED, AND NEITHER THESE WARRANTS NOR ANY INTEREST
THEREIN MAY BE TRANSFERRED, HYPOTHECATED OR OTHERWISE DISPOSED OF WITHOUT
REGISTRATION UNDER THAT ACT OR AN OPINION OF COUNSEL ACCEPTABLE TO THE COMPANY
THAT SUCH REGISTRATION IS NOT REQUIRED.

No. I2-____                                   Warrant to Purchase _______ Shares
March [__], 2003                                 of Common Stock, $.01 Par Value





                     SECOND WARRANT TO PURCHASE COMMON STOCK
                                       of
                       PROTEIN POLYMER TECHNOLOGIES, INC.,
                             a Delaware corporation
                             Expires: March 31, 2007



            This certifies that, for value received, ___________________ or
registered assigns ("Holder") is entitled, subject to the terms set forth below,
to purchase from Protein Polymer Technologies, Inc., a Delaware corporation (the
"Company"), _______ shares of Common Stock, $.01 par value, of the Company (such
class of stock being referred to herein as "Common Stock"), as constituted on
March [__], 2003 (the "Issue Date"), upon surrender of this Warrant, at the
principal office of the Company referred to below, with the subscription form
attached hereto duly executed, and simultaneous payment therefor in the
consideration specified in Section 1 hereof, at the price of $1.65 per share
(the "Purchase Price"). This Warrant must be exercised, if at all, on or prior
to March 31, 2007. The shares of Common Stock issued or issuable upon exercise
of this Warrant are sometimes referred to as the "Warrant Shares." The term
"Warrants" as used herein shall include this Warrant and any warrants delivered
in substitution or exchange therefor as provided herein.

            1. Exercise. This Warrant may be exercised at any time or from time
to time, on any business day, for all or part of the full number of shares of
Common Stock during the period of time called for hereby, by surrendering it at
the principal office of the Company, 10655 Sorrento Valley Road, First Floor,
San Diego, California 92121, with the subscription form duly executed, together
with payment for the Warrant Shares payable in cash and/or by check for same day
funds. No other form of consideration


<PAGE>


shall be acceptable for the exercise of this Warrant. A Warrant shall be deemed
to have been exercised immediately prior to the close of business on the date of
its surrender for exercise as provided above, and the person entitled to receive
the shares of Common Stock issuable upon such exercise shall be treated for all
purposes as the holder of such shares of record as of the close of business on
such date. As soon as practicable on or after such date, and in any event within
10 days thereof, the Company shall issue and deliver to the person or persons
entitled to receive the same a certificate or certificates for the number of
shares of Common Stock issuable upon such exercise. Upon any partial exercise,
the Company will issue and deliver to Holder a new Warrant or Warrants with
respect to the shares of Common Stock not so transferred. No fractional shares
of Common Stock shall be issued upon exercise of a Warrant. In lieu of any
fractional share to which Holder would be entitled upon exercise, the Company
shall pay cash equal to the product of such fraction multiplied by the Common
Stock Value (as defined in the Company's Certificate of Designation of Series I
Preferred Stock) on the date of exercise.

            2. Payment of Taxes. All shares of Common Stock issued upon the
exercise of a Warrant shall be duly authorized, validly issued and outstanding,
fully paid and non-assessable. Holder shall pay all taxes and other governmental
charges that may be imposed in respect of the issue or delivery thereof and any
tax or other charge imposed in connection with any transfer involved in the
issue of any certificate for shares of Common Stock in any name other than that
of the registered Holder of the Warrant surrendered in connection with the
purchase of such shares, and in such case the Company shall not be required to
issue or deliver any stock certificate until such tax or other charge has been
paid or it has been established to the Company's satisfaction that no tax or
other charge is due.

            3. Transfer and Exchange. Subject to the provisions of Section 8,
this Warrant and all rights hereunder are transferable, in whole but not in
part, only with the prior approval of the Company, which consent shall not be
unreasonably withheld. If such a proposed transfer is so approved, this Warrant
is transferable on the books of the Company maintained for such purpose at its
principal office referred to above by Holder in person or by duly authorized
attorney, upon surrender of this Warrant properly endorsed and upon payment of
any necessary transfer tax or other governmental charge imposed upon such
transfer. Notwithstanding the foregoing, the restrictions imposed upon the
transferability of the Warrant do not apply to transfers made by the Holder, in
whole or in part, to any subsidiary, parent, affiliate, general partner or
limited partner of the Holder. Each taker and holder of this Warrant, by taking
or holding the same, consents and agrees that this Warrant, when endorsed in
blank, shall be deemed negotiable and that when this Warrant shall have been so
endorsed, the Holder hereof may be treated by the Company and all other persons
dealing with this Warrant as the absolute owner hereof for any purpose and as
the person entitled to exercise the rights represented hereby or to the transfer
hereof on the books of the Company, any notice to the contrary notwithstanding;
but until such transfer on such books, the Company may treat the registered
Holder hereof as the owner for all purposes.


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<PAGE>


            4. Certain Adjustments.

               4.1 Adjustment for Reorganization, Consolidation, Merger. In case
of any reorganization of the Company (or any other corporation, the stock or
other securities of which are at the time receivable on the exercise of this
Warrant) after the Issue Date, or in case, after such date, the Company (or any
such other corporation) shall consolidate with or merge into another corporation
(other than the merger of a wholly owned subsidiary into the Company) or convey
all or substantially all its assets to another corporation, then and in each
such case Holder, upon the exercise hereof as provided in Section 1 at any time
after the consummation of such reorganization, consolidation, merger or
conveyance, shall be entitled to receive, in lieu of the stock receivable upon
the exercise of this Warrant prior to such consummation, the stock or other
securities or property to which such Holder would have been entitled upon such
consummation if such Holder had exercised this Warrant immediately prior
thereto.

               4.2 Adjustments for Dividends in Common Stock. If the Company at
any time or from time to time after the Issue Date declares, or fixes a record
date for the determination of holders of Common Stock entitled to receive, a
dividend payable in additional shares of Common Stock, then and in each such
event the Purchase Price then in effect shall be decreased as of the time of
such issuance or, in the event such record date is fixed, as of the close of
business on such record date, by multiplying the Purchase Price then in effect
by a fraction (1) the numerator of which is the total number of shares of Common
Stock issued and outstanding immediately prior to the time of such issuance or
the close of business on such record date, and (2) the denominator of which
shall be the total number of shares of Common Stock issued and outstanding
immediately prior to the time of such issuance or the close of business on such
record date plus the number of shares of Common Stock issuable in payment of
such dividend; provided, however, that if such record date is fixed and such
dividend is not fully paid on the date fixed therefor, the Purchase Price shall
be recomputed accordingly as of the close of business on such record date and
thereafter the Purchase Price shall be adjusted pursuant to this Section 4.2 as
of the time of actual payment of such dividends.

               4.3 Stock Split and Reverse Stock Split. If the Company at any
time or from time to time after the Issue Date effects a subdivision of the
outstanding Common Stock, the Purchase Price then in effect immediately before
that subdivision shall be proportionately decreased and the number of shares of
Common Stock theretofore receivable upon the exercise of this Warrant shall be
proportionately increased. If the Company at any time or from time to time after
the Issue Date combines the outstanding shares of Common Stock into a smaller
number of shares, the Purchase Price then in effect immediately before that
combination shall be proportionately increased and the number of shares of
Common Stock theretofore receivable upon the exercise of this Warrant shall be
proportionately decreased. Each adjustment under this Section 4.3 shall become
effective at the close of business on the date the subdivision or combination
becomes effective.

               4.4 Accountants' Certificate as to Adjustment. In each case of an
adjustment in the shares of Common Stock receivable on the exercise of the
Warrants,


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<PAGE>


the Company at its expense shall cause its chief financial officer to compute
such adjustment in accordance with the terms of the Warrants and prepare a
certificate setting forth such adjustment and showing the facts upon which such
adjustment is based. The Company will forthwith mail a copy of each such
certificate to each holder of a Warrant at the time outstanding at the holder's
address as shown in the Company's books.

            5. Loss or Mutilation. Upon receipt by the Company of evidence
satisfactory to it (in the exercise of reasonable discretion) of the ownership
of and the loss, theft, destruction or mutilation of any Warrant and (in the
case of loss, theft or destruction) of indemnity satisfactory to it (in the
exercise of reasonable discretion), and (in the case of mutilation) upon
surrender and cancellation thereof, the Company will execute and deliver in lieu
thereof a new Warrant of like tenor.

            6. Reservation of Common Stock. The Company shall at all times
reserve and keep available out of its authorized but unissued shares of Common
Stock, solely for the purpose of effecting the exercise of the Warrant, such
number of its shares of Common Stock as shall from time to time be sufficient to
effect exercise of the Warrant; and if at any time the number of authorized but
unissued shares of Common Stock shall not be sufficient to effect such exercise,
the Company will take such corporate action as may, in the opinion of its
counsel, be necessary to increase its authorized but unissued shares of Common
Stock to such number of shares as shall be sufficient for such purpose, and may
obtain agreements from a certain number of its holders of securities convertible
into or exchangeable for shares of Common Stock not to convert or exchange their
securities until the Company has taken such corporate action.

            7. Notices of Record Date. In the event of (i) any taking by the
Company of a record of the holders of any class of securities for the purpose of
determining the holders thereof who are entitled to receive any dividend or
other distribution, or (ii) any capital reorganization of the Company, any
reclassification or recapitalization of the capital stock of the Company, any
merger or consolidation of the Company with or into any other corporation (other
than a merger of a wholly owned subsidiary into the Company), or any transfer of
all or substantially all of the assets of the Company to any other person or any
voluntary or involuntary dissolution, liquidation or winding up of the Company,
the Company shall mail to the Holder at least thirty (30) days prior to the
record date specified therein, a notice specifying (1) the date on which any
such record is to be taken for the purpose of such dividend or distribution and
a description of such dividend or distribution, (2) the date on which any such
reorganization, reclassification, transfer, consolidation, merger, dissolution,
liquidation or winding up is expected to become effective, and (3) the date, if
any, that is to be fixed, as to when the holders of record of Common Stock (or
other securities) shall be entitled to exchange their shares of Common Stock (or
other securities) for securities or other property deliverable upon such
reorganization, reclassification, transfer, consolidation, merger, dissolution,
liquidation or winding up.


                                      -4-
<PAGE>


            8. Investment Representation and Restriction on Transfer.

               8.1 Securities Law Requirements.

                   (a) By its acceptance of this Warrant, Holder hereby
represents and warrants to the Company that this Warrant and the Warrant Shares
will be acquired for investment for its own account, not as a nominee or agent,
and not with a view to the sale or distribution of any part thereof, and that it
has no present intention of selling, granting participations in or otherwise
distributing the same. By acceptance of this Warrant, Holder further represents
and warrants that it does not have any contract, undertaking, agreement or
arrangement with any person to sell, transfer or grant participations to any
person, with respect to this Warrant or the Warrant Shares.

                   (b) By its acceptance of this Warrant, Holder understands
that this Warrant is not, and the Warrant Shares will not be, registered under
the Securities Act of 1933, as amended (the "Act"), on the basis that the
issuance of this Warrant and the Warrant Shares are exempt from registration
under the Act pursuant to Section 4(2) thereof, and that the Company's reliance
on such exemption is predicated on Holder's representations and warranties set
forth herein.

                   (c) By its acceptance of this Warrant, Holder understands
that the Warrant and the Warrant Shares may not be sold, transferred, or
otherwise disposed of without registration under the Act, or an exemption
therefrom, and that in the absence of an effective registration statement
covering the Warrant and the Warrant Shares or an available exemption from
registration under the Act, the Warrant and the Warrant Shares must be held
indefinitely. In particular, Holder is aware that the Warrant and the Warrant
Shares may not be sold pursuant to Rule 144 promulgated under the Act unless all
of the conditions of Rule 144 are satisfied. Among the conditions for use of
Rule 144 are the availability of current information about the Company to the
public, prescribed holding periods which will commence only upon Holder's
payment for the securities being sold, manner of sale restrictions, volume
limitations and certain other restrictions. By its acceptance of this Warrant,
Holder represents and warrants that, in the absence of an effective registration
statement covering the Warrant or the Warrant Shares, it will sell, transfer or
otherwise dispose of the Warrant and the Warrant Shares only in a manner
consistent with its representations and warranties set forth herein and then
only in accordance with the provisions of Section 8.1(d).

                   (d) By its acceptance of this Warrant, Holder agrees that in
no event will it transfer or dispose of any of the Warrants or the Warrant
Shares other than pursuant to an effective registration statement under the Act,
unless and until (i) Holder shall have notified the Company of the proposed
disposition and shall have furnished the Company with a statement of the
circumstances surrounding the disposition, and (ii) if reasonably requested by
the Company, at the expense of the Holder or transferee, it shall have furnished
to the Company an opinion of counsel, reasonably satisfactory to the Company, to
the effect that (A) such transfer may be made without registration under the Act
and (B) such transfer or disposition will not cause the termination or the
non-applicability of any exemption to the registration and prospectus


                                      -5-
<PAGE>


delivery requirements of the Act or to the qualification or registration
requirements of the securities laws of any other jurisdiction on which the
Company relied in issuing the Warrant or the Warrant Shares; provided, however,
that such opinion need not be furnished for the transfer of the Warrant or
Warrant Shares, in whole or in part, to any subsidiary, parent, affiliate,
general partner or limited partner of the Holder.

               8.2 Legends; Stop Transfer.

                   (a) All certificates evidencing the Warrant Shares shall bear
a legend in substantially the following form:

            The securities represented by this certificate have not
            been registered under the Securities Act of 1933. These
            securities have been acquired for investment and not with
            a view to distribution and may not be offered for sale,
            sold, pledged or otherwise transferred in the absence of
            an effective registration statement for such securities
            under the Securities Act of 1933 or an opinion of counsel
            reasonably satisfactory in form and content to the issuer
            that such registration is not required under such Act.

                   (b) The certificates evidencing the Warrant Shares shall also
bear any legend required by any applicable state securities law.

                   (c) In addition, the Company shall make, or cause its
transfer agent to make, a notation regarding the transfer restrictions of the
Warrant and the Warrant Shares in its stock books, and the Warrant and the
Warrant Shares shall be transferred on the books of the Company only if
transferred or sold pursuant to an effective registration statement under the
Act covering the same or pursuant to and in compliance with the provisions of
Section 8.1(d).

            9. Notices. All notices and other communications from the Company to
the Holder of this Warrant shall be mailed by first-class registered or
certified mail, postage prepaid, to the address shown in the Company's books.

            10. Change; Waiver. Neither this Warrant nor any term hereof may be
changed, waived, discharged or terminated orally, but only by an instrument in
writing signed by the party against which enforcement of the change, waiver,
discharge or termination is sought.

            11. Headings. The headings in this Warrant are for purposes of
convenience in reference only, and shall not be deemed to constitute a part
hereof.


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<PAGE>


            12. Governing Law. This Warrant is delivered in California and shall
be construed and enforced in accordance with and governed by the internal laws,
and not the law of conflicts, of such State; provided however, that to the
extent that an issue of determination is one of corporate law, then the Delaware
General Corporation Law shall govern.

                           PROTEIN POLYMER TECHNOLOGIES, INC.,
                             a Delaware corporation



                           By
                              -------------------------------------
                              J. Thomas Parmeter, President


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<PAGE>


                                SUBSCRIPTION FORM
                                -----------------
                 (To be executed only upon exercise of Warrant)


            The undersigned, registered owner of this Warrant, irrevocably
exercises this Warrant and purchases ____________ of the number of shares of
Common Stock, $.01 par value, of PROTEIN POLYMER TECHNOLOGIES, INC., a Delaware
corporation, purchasable with this Warrant, and herewith makes payment therefor,
all at the price and on the terms and conditions specified in this Warrant.

DATED:______________

                                    ______________________________
                                    (Signature of Registered Owner)

                                    ______________________________
                                    (Street Address)

                                    ______________________________
                                    (City)      (State)      (Zip)


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<PAGE>


                               FORM OF ASSIGNMENT
                               ------------------

            FOR VALUE RECEIVED the undersigned, registered owner of this
Warrant, hereby sells, assigns and transfers unto the Assignee named below all
of the rights of the undersigned under the within Warrant, with respect to the
number of shares of Common Stock, $.01 par value, set forth below:

Name of Assignee              Address           No. of Shares
----------------              -------           -------------




and does hereby irrevocably constitute and appoint __________________________
_________________________________________________ Attorney to make such transfer
on the books of PROTEIN POLYMER TECHNOLOGIES, INC., a Delaware corporation,
maintained for the purpose, with full power of substitution in the premises.

DATED: ___________________

                                            __________________
                                               (Signature)

                                            __________________
                                                 (Witness)


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