International Chemical Safety Cards 

UREA ICSC: 0595 

Carbamide 

Carbonyldiamide 

NH2CONH2 / CH4N2O 

Molecular mass: 60.1 

ICSC # 0595 

CAS # 57-13-6 

RTECS # YR6250000

July 10, 1997 Validated 

TYPES OF 

HAZARD/ 

EXPOSURE 

ACUTE HAZARDS/ 

SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING 

FIRE 

Not combustible. Gives off 

irritating or toxic fumes (or 

gases) in a fire. 

In case of fire in the 

surroundings: all extinguishing 

agents allowed. 

EXPLOSION 

EXPOSURE PREVENT DISPERSION OF 

DUST! 

 •INHALATION Cough. Shortness of breath. Sore 

throat. 

Local exhaust. Fresh air, rest. 

 •SKIN Redness. Protective gloves. Rinse and then wash skin with 

water and soap. 

 •EYES 

Redness. Safety spectacles. First rinse with plenty of water 

for several minutes (remove 

contact lenses if easily possible), 

then take to a doctor. 

 •INGESTION Convulsions. Headache. Nausea. 

Vomiting. 

Do not eat, drink, or smoke 

during work. 

Give plenty of water to drink. 

Rest. 

SPILLAGE DISPOSAL STORAGE PACKAGING & 

LABELLING 

Sweep spilled substance into 

containers; if appropriate, moisten first 

to prevent dusting. Wash away 

remainder with plenty of water. 

Separated from incompatible materials, 

(see chemical dangers). 

SEE IMPORTANT INFORMATION ON BACK 

ICSC: 0595 Prepared in the context of cooperation between the International Programme on Chemical Safety & the 

Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version 

have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values. 

International Chemical Safety Cards 

ICSC:NENG0595 International Chemical Safety Cards (WHO/I... Iris Camacho, 6308MM Page 1 of 2

http://www.cdc.gov/niosh/ipcsneng/neng0595.html 8/9/2011
UREA ICSC: 0595 

I 

M 

P 

O 

R 

T 

A 

N 

T 

D 

A 

T 

A 

PHYSICAL STATE; APPEARANCE: 

WHITE CRYSTALS , WITH 

CHARACTERISTIC ODOUR. 

PHYSICAL DANGERS: 

CHEMICAL DANGERS: 

The substance decomposes on heating above 

melting point producing toxic gases. Reacts 

violently with strong oxidants, nitrites, 

inorganic chlorides, chlorites and perchlorates 

causing fire and explosion hazard. 

OCCUPATIONAL EXPOSURE LIMITS: 

TLV not established. 

ROUTES OF EXPOSURE: 

The substance can be absorbed into the body by 

inhalation of its aerosol and by ingestion. 

INHALATION RISK: 

Evaporation at 20°C is negligible; a nuisancecausing concentration of airborne particles can, 

however, be reached quickly if powdered. 

EFFECTS OF SHORT-TERM EXPOSURE:

The substance irritates the eyes, the skin and the 

respiratory tract. 

EFFECTS OF LONG-TERM OR 

REPEATED EXPOSURE: 

Repeated or prolonged contact with skin may 

cause dermatitis. 

PHYSICAL 

PROPERTIES 

Melting point: 132.7-135°C 

Density: 1.32 

Solubility in water: miscible 

Octanol/water partition coefficient as log Pow: 

-3.00 to -1.54 

ENVIRONMENTAL 

DATA 

N O T E S 

Temperature of decomposition unknown in literature. 

ADDITIONAL INFORMATION 

ICSC: 0595 UREA 

(C) IPCS, CEC, 1994 

IMPORTANT 

LEGAL 

NOTICE: 

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the 

IPCS is responsible for the use which might be made of this information. This card contains the 

collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed 

requirements included in national legislation on the subject. The user should verify compliance of the 

cards with the relevant legislation in the country of use. The only modifications made to produce the 

U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values. 

ICSC:NENG0595 International Chemical Safety Cards (WHO/I... Iris Camacho, 6308MM Page 2 of 2

http://www.cdc.gov/niosh/ipcsneng/neng0595.html 8/9/2011