### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 2 of 25 

## America, (NHANES/WWEIA). This dietary survey was conducted from 2003 to 2008. Dietary risk assessments were performed to suppor t a Section 3 registration application submitted by Mitsui Chemicals Agro, Inc. (Mitsui), through its authorized agent, Landis International, Inc., is requesting the establishment of a tolerance for dinotefuran on rice. In conjunction with this petition, Mitsui is requesting amended registration of a water soluble granule (SG) formulation of dinotefuran (LX434 Dinotefuran 20 SG; EPA Reg.

No. 86203

- 25) to add use on rice.

Additionally, BASF Corporation, through its authorized agent, Landis International, is requesting the establishment of a tolerance for residues of dinotefuran in/on all food/feed items (other than those already covered by a higher tolerance as a result of use on growing crops) in food/feed handling establishments (FHE) where food product s are held, processed or prepared. In conjunction with this petition, BASF is requesting amended registration of three ready

- to

- use dinotefuran products: a 0.5% pressurized liquid formulation (TC 267; Alpine® Pressurized Insecticide; EPA Reg. No. 499

- 531 ); a 0.025% foam formulation (Whitmire Micro

- Gen TC 259; AlpineTM Ant and Termite Foam; EPA Reg. No. 499

- 526); and a 0.25% dustable powder formulation (TC 249; Dino Dust Insecticide; EPA Reg. No. 499

- 527). The products are proposed for crack and crevice, s pot, and general treatment applications in food/feed

- handling establishments.

The most recent a cute and chronic aggregate dietary assessments were conducted for

dinotefuran in July 2012 ( D 391885

, Barry O’Keefe

, 20

- JULY

- 2012 ).

Acute Dietary Exposure R esults and Characterization

.

An u nrefined acute screening

- level dietary assessment was conducted assuming that all

of the crops associated with the requested and currently re gistered uses of dinotefuran are 100% treated and that all treated crops contain residues at tolerance level s

. In addition,

default processing factors were assumed for both registered and requested crop uses

. Potential residues in drinking water were included in the analyses based on s urface water

results from the provisionally modif ied Tier 1 Rice Model v.1.0 as these val ues were higher than the ground water estimates from the Screening Concentration in Ground Water ( SCI GROW ) model ( D 397490

, James Wolf

, 7

- AUG

- 201 2 ). T he results obtained from the present dietary analyses may be consi dered highly conservative. At the 95 th


## percentile of exposure, no population subgroups exceed HED’s level of concern: the

U

. S

. population occupied 3.0 % of the acute population

- a djusted d ose ( a PA D) , while the most high ly exposed population subgroup, all i nfants

, occupied 7.6 % of the a PA D

.

Chronic Dietary Exposure Results and Characterization

An unrefined chronic screening

- level dietary assessment was conducted assuming that all of the crops associated with the requested and currently registered uses of dinotefuran are 100% treated and that all treated crops contain residues at tolerance level s

. In addition, default processing factors were assumed for both registered and requested crop uses

. Potential residues in drinking water were included in the ana lyses based on surface water

results from the modified Tier 1 Rice Model as these values were higher than the groundwater estimates from the SCIGROW model ( D 397490, James Wolf

, 7

- AUG

-

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 3 of 25 

## 201 2 ). N o population subgroups exceed HED’s level of concern: the U

. S

. population occupied 1.4 % of the chronic population

- a djusted d ose (c PA D), while the most highly exposed population subgroup, Chi ldren 1

- 2 years old, occupied 3.9 % of the c PA D.

Cancer Dietary Exposure Results and Characterization

A determination of canc er risk was not performed with DEEM

- FCIDTM as part of the

present assessment, since this chemical was classified as “Not likely to be Carcinogenic

to Humans” based on negative genotoxicity and carcinogenicity in long term cancer

studies in rats and mice.

I

. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). This dose i s referred to as the population

- adjusted dose (PAD). The PAD is equivalent to point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety factors.

For acute and non

- c ancer chronic exposures, HED is concerned when estimated dietary

risk exceeds 100% of the PAD. References which discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site: “Available

Information on Assessin g Exposure from Pesticides, A User’s Guide,” 21

- JUN

- 2000,

web link: http://www.epa.gov/fedrgstr/EPA

- PEST/2000/July/Day

- 12/6061.pdf ; or see SOP 99.6 (20

- AUG

- 1999).

The most recent dietary risk assessment for d inote furan was conducted to support FIFRA §3 registrations ( D 391885

, Barry O’Keefe, 20

- JULY

- 2012 ).

II. Residue Information

Dinotefuran [( RS )

- 1

- methyl

- 2

- nitro

- 3

- (tetrahydro

- 3

- furylmethyl)guanidine] is a Group

4A insec ticide for which permanent tolerances have been established under 40 CFR§180.603(a) for the combined residues of dinotefuran and its metabolites DN [1

- methyl

- 3

- (tetrahydro

- 3

- furylmethyl)guanidine], and UF [1

- methyl

- 3

- (tetrahydro

- 3

- furylmethyl)

- urea)]. The tolerance levels established for the following commodities range from 0.05 ppm to 15.0 ppm : Brassica (subgroup 5A and 5B), cotton, grape, grape/raisin, potato, potato chips, potato granules/flakes, tomato paste, turnip greens, fruiting vegetables, cucurbi ts, and leafy vegetables. Tolerances have also been established under 180,603(b) at 0.05 ppm for the fat, meat

, and meat by products of cattle, goat s , hog s , horse s , sheep , and milk. A FIFRA §18 emergency exemption tolerance currently exists for rice, gra in at 2.8 ppm. Additionally, there are pending tolerances on the following crops: berry, low growing, except strawberry, subgroup 13

- 07H; fruit, small, vine climbing, except fuzzy kiwifruit, subgroup 13

- 07F; onion, bulb, subgroup 3

- 07A; onion, green, subg roup 3

- 07B; vegetable, tuberous and corm, subgroup 1C; peach; and watercress.

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 4 of 25 

## The nature of the residue in plants and livestock commodities is understood (MARC report, TXR #52304, DP293759, L. Cheng, 1/20/2004). In plants, parent dinotefuran and

the metab olites DN and UF are the residues of concern for tolerance monitoring, and dinotefuran, DN, UF

, and PHP are the residues of concern for risk assessment. In livestock, dinotefuran is the residue of concern for tolerance monitoring, and dinotefuran

and meta bolites UF and FNG in ruminants, and dinotefuran and the metabolite FNG in poultry for risk assessment.

For both the acute and chronic dietary analyse s, the existing , pending, and recommended

tolerance s were used for each food commodity residue level. Default processing factors

were also used except for dry potatoes, tomato paste, and grape raisins where tolerances

are established

. The acute and chronic assessment s also assume that 100% of the crops are treated. Table 1 summarizes the dinotefuran resi due levels for the recommended, pending, and currently registered crops used in the acute and chronic dietary assessments.

It should be noted that the FHE use was only included in the chronic assessment.

Additionally , for the proposed use on rice, HE D has concluded that no changes are needed to the existing tolerances for milk, ruminant or swine tissues as a result of the addition of rice grain or bran to the diet. For poultry, with the increased dietary burden resulting from the proposed use on rice , and in consideration of the results from the available poultry metabolism study, HED concludes that poultry tolerances in egg and liver at the LOQ of 0.01 ppm are now needed (DP397469, L. Cheng, 8/15/12)

.

Table 1. Summary of Dinotefuran Residue Level s For Pending, Recommended and Established

Tolerances Used in Acute and Chronic Analyses. Commodity Tolerance Level [Acute and Chronic] (ppm) Berry, low growing, except strawberry, subgroup 13

- 07H 3 

### 0.2

Brassica , head and stem, subgroup 5A 1 

### 1.4

Bra s sic a , leafy greens, subgroup 5B 1 

### 15.0 Cattle, goat, hog, horse, and sheep 1



### F at, meat, and meat by products

Milk 0.05

Egg 2 

### 0.01 Poultry, meat byproducts 2 

### 0.01
Cotton, undelinted seed 1 

### 0.4 Fruit, pome 4 

### 1.0 Fruit, small, vine climbing, except fuzzy ki wifruit, subgroup 13

- 07F 3 

### 0.9

Fruit, stone 4 

### 1.0 Grape, raisin 1 

### 2.5 Onion, bulb, subgroup 3

- 07A 3 

### 0.15 Onion, green, subgroup 3

- 07B 3 

### 5 .0

Peach 3 

### 1.0 Potato, chips 1 

### 0.1 Potato, granules/flakes 1 

### 0.15 Rice, grain 2 

### 9
Tea, dried 3 

### 50 Tomato, paste 1 

### 1.0

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 5 of 25 Table 1. Summary of Dinotefuran Residue Level s For Pending, Recommended and Established

Tolerances Used in Acute and Chronic Analyses. Commodity Tolerance Level [Acute and Chronic] (ppm) Turnip greens 1 

### 15.0 Vegetable, fruiting, group 8 1 

### 0.7 Vegetable, cucurbit, group 9 1 

### 0.5 Vegetable, leafy, except Brassica , group 4 1 

### 5.0 Vegetable, tuberous and corm, subgroup 1C 3 

### 0.05

Watercress 3 

### 8.0 All food/feed items (other than those already cove red by a higher tolerance as a result of use on growing crops) in food/feed handling establishments where food products are held, processed or prepared 2 

### 0.01

1 Current Section 3 tolerance

2 Recommended tolerance 3 Pending tolerance

4 Current Section 18 to lerance



## III. Drinking Water Data

There are no drinking water monitoring data available on the concentrations of parent dinotefuran or any of its’ degradates. EFED provided a Tier 1 dinotefuran drinking water assessment with estimated drinking water co ncentrations (EDWCs) for dinotefuran and its metabolite/degradate DN ( DP397490, J. Wolf & J. Hetrick , 8/7/12 ).

In addition to its registered Section 3 uses there is an active dinotefuran Section 18 for use on rice in Texas. For the Section 18, a drinki ng water assessment was previously prepared for dinotefuran and its transformation products MNG, DN, UF, and DN

- 2

- OH +

DN

- 3

- OH, in support of the use on rice in Texas (surface water) and turf (ground water). Based upon the results of an additional aerobic and anaerobic aquatic metabolism study, EFED has determined that the major transformation product in an aquatic environment such as a rice paddy would be the degradate DN only.

For this assessment, the EDWCs for dinotefuran and DN degradates for surfac e water were obtained using the modified Tier 1 Rice Model which assumes that only aerobic and anaerobic aquatic metabolism processes occur in the rice paddy during the holding period. Ground water EDWCs were obtained with the Tier 1 SCI

- GROW model v.2.3

. SCI

- GROW is used for the rice assessment because the PRZM

- GW is not applicable for paddy (flooded) conditions (i.e., water column over lying soil) and saturated conditions.

Table 2 summarizes the surface water EDWCs for dinotefuran and DN degradate. The peak concentration is 269 μg/L and the longer term concentration (≈average) would depend upon retention time (10 to 30 days).

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 6 of 25 Table 2 . Tier 1 Surface Water EDWCs (μg/L) for Drinking Water Risk Assessment for the Use of

Dinotefuran on Rice. Base d upon total toxic residues (Dinotefuran + DN).

Peak Retention Time

10 day 30 day 60 day 100 day 150 day

269 257 253 248 240 198



## The ground water EDWC, obtained using the Tier 1 SCI

- GROW , is the same value for

the turf use and the Section 18 rice use ; 4.90 μg/L for both the acute and chronic exposures. Since the application rate for turf (1 application at 0.54 l b ai/A) is higher than

for rice and since SCI

- GROW is not site or crop dependent

, the resulting water

concentration is considered to be conse rvative.

Because the surface water estimates are higher than the groundwater estimates, the surface water values, expressed to two significant figures and converted to ppm, were directly incorporated in the DEEM

- FCID into the food categories “water, direc t, all sources” and “water, indirect, all sources.” The peak value was used in the acute assessment and the 10 day retention time value was used in the chronic assessment.

IV. DEEM

- FCIDTM Program and Consumption Information

Dinotefuran acute and chronic dietary exposure assessments were conducted using the Dietary Exposure Evaluation Model software with the Food Commodity Intake Database

DEEM

- FCID, Version 3.16, which incorp orates consumption data from USDA’s NHANES/WWEIA. This dietary survey was conducted from 2003 to 2008. The data are based on the reported consumption of more than 20,000 individuals over two non

consecutive survey days. Foods “as consumed” (e.g., apple pie) are linked to EPA

defined food commodities (e.g.

, apples, peeled fruit

- cooked; fresh or N/S; baked; or

wheat flour

- cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA. For chronic e xposure assessment, consumption data are averaged for the entire US population and within population subgroups. Based on analysis of the 1994

- 96, 98 CSFII consumption data, which took into account dietary patterns of survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children 1

- 2, children 3

- 5, children 6

- 12, youth 13

- 19, adults 20

- 49, females 13

- 49, and adults 50+ years old.

For chron ic dietary exposure assessment s , an estimate of the residue level in each food or

food

- form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a resid ue intake estimate. The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure. Exposure is expre ssed in mg/kg body weight/ day and as a percent of the cRfD . This procedure is performed for each population subgroup.

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 7 of 25 

## For acute exposure assessments, individual one

- day food consumption data are used on

an individual

- by

- individual basis. The reported co nsumption amounts of each food item can be multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or “matched” in multiple random pairings with residue values and then summed in a probabilistic assessment. The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per

capita (i.e., those who reported eating the relev ant commodities as well as those who did not) basis. In accordance with HED policy, per capita exposure and risk are reported for all tiers of analysis.

V. Toxicological Information

All information specific to th e t oxicity characteristics of dinotefur an is presented in the

most risk assessment ( Barry O’Keefe et. al.

, July

- 2012 ). For the acute and c hronic exposure scenario s , the standard 100 fold UF was applied to account for inter

- species extrapolation and intra

- species variation

.

As previously not ed, a cancer risk evaluation is not included in this assessment. To provide an overview of the toxicological profile, a summary of the doses and endpoints

selected for the re le vant dietary exposure scenarios is provided in Table 3

.

Table 3

. Summary of Toxicological Doses and Endpoints for Dinotefuran for Use in Dietary Exposure Risk Assessments

. Exposure/

Scenario Point of

Departure Uncertainty/FQPA

Safety Factors RfD, PAD, Level

of Concern Study and Toxicological

Effects

Acute Dietary (General Popu lation

, including

Infants and Children) NOAEL=125

mg/kg/day UF A 

### = 10x

UF H 

### = 10x FQPA SF= 1x Acute RfD = 1.25

mg/kg/day

aPAD =1.25 mg/kg/day Developmental Toxicity Study

in Rabbits LOAEL = 300 mg/kg/day based on clinical signs in does (prone position, tremor

, erythema) seen following a single dose.

Chronic Dietary (All Populations) NOAEL=99.7

mg/kg/day UF A 

### = 10x

UF H 

### = 10x FQPA SF= 1x Chronic RfD =

1.0 mg/kg/day

cPAD = 1.0 mg/kg/day C hronic /Carcinogenicity Study

in Rats

L OAEL = 991 mg/kg/day

based on decrease d body weight gain in females and evidence of nephrotoxicity

. Cancer Classification: “Not likely to be Carcinogenic to Humans” based on the absence of significant tumor increases in two adequate rodent carcinogenicity studies. Point of Departure (POD) = A data point or an estimated point that is derived from observed dose

- response data and used to mark the beginning of extrapolation to determine risk associated with lower environmentally relevant human exposures. NOAEL = no observed adverse effect lev el. LOAEL = lowest observed adverse effect level. UF = uncertainty factor. UF A 

### = extrapolation from animal to human (interspecies). UF H 

### = potential variation in sensitivity among members of the human population (intraspecies ). FQPA SF = FQPA Safety Fa ctor. PAD = population adjusted dose (a = acute, c = chronic). RfD = reference dose. MOE = margin of exposure. LOC = level of concern.

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 8 of 25 

## VI. Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk

exc eeds 100% of the PAD. The DEEM

- FCIDTM analyses estimat e the dietary exposure

of the U

. S

. population and various population subgroups. The results reported in Table 4 are for the general US Population, all infants (<1 year old), children 1

- 2, children 3

- 5,

children 6

- 12, youth 13

- 19, females 13

- 49, adults 20

- 49, and adults 50+ years.

Results of Acute and Chronic Dietary (Food and Drinking Water) Exposure Analysis

Acute dietary risk a nalyses were conducted with the DEEM

- FCIDTM model to form a

conservative evaluation of exposure for dinotefuran

. At the 95 th 

## percentile of exposure,

a ll acute analys e s yielded risk estimates well below the 100% of the aPA D threshold level of concern for each population subgroup. For the U

. S

. Population subgroup, acute

aggreg ate di eta ry risk was calcul ated at 3.0 % of the aPAD wi th an exposure level of

0.0 37384 mg/kg/day. For the subgroup with the highest calculated exposure, all infants

, acute aggregate dietary risk occupied 7.6 % of the aPA D with an exposure of 0.0 9 4678 mg/kg /day. An overview summarizing the results of the acute dietary assessments with the population subgroup having the highest exposure noted in bold is presented in Table

4

.

C hronic dietary risk a nalys e s were conducted with the DEEM

- FCIDTM model to form a

co nservative evaluation of exposure for dinotefuran

. All chronic analys e s yield ed risk

estimates well below the 100% of the c PA D threshold level of concern for each population subgroup. For the U

. S

. Population subgroup, chronic aggregate dietary risk

w as c alculated at 1.4 % of the cPA D with an exposure level of 0.0 14 212 mg/kg/day. For the subgroup with the highest calculated exposure, Children 1

- 2 years old

, chronic

aggregate dietary risk occupied 3.9 % of the c PA D with an exposure of 0.0 38 570 mg/kg/day. An overview summarizing the results of the chronic dietary assessment with the population subgroup h aving the highest exposure noted in bold is presented in Table

4

.

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 9 of 25 Table 4. Result of Acute and Chronic Dietary Exposure and Risk Estimates for Dinotefuran using DEEM

- FCID (food and water)

.

Population Subgroup* Acute Dietary (95 th 

### Percentile) Chronic Dietary

Dietary Exposure (mg/kg/day) % aPAD** Dietary Exposure (mg/kg/day) % cPAD**

General U.S. Population 0.037384 3.0 0.014212 

### 1.4

All Infants (< 1 year old) 0.095276 7.6 0.035606 

### 3.6

Children 1

- 2 years old 0.094678 7.6 0.038570 

### 3.9

Children 3

- 5 years old 0.069524 5.6 0.027569 

### 2.8

Children 6

- 12 years old 0.040299 3.2 0.015393 

### 1. 6

Youth 13

- 19 years old 0.026648 2. 4 0.009989 

### 1.0

Adults 20

- 49 years old 0.031301 2.5 0.012827 

### 1.3

Adults 50

- 99 years old 0.027932 2.2 0.012054 

### 1.2

Fe males 13

- 49 years old 0.030602 2. 5 0.012242 

### 1.2

*The values for the highest exposed population for each type of risk assessment are bolded. ** Report %PADs to 2 significant figures.



## VII. Characterization of Inputs/Outputs

The acute screening

- level dietary assessment conducted with DEEM

- FCIDTM for

dinotefuran is an unrefined analysi s. In addition to tolerance level residues, default processing factors

, and 100% crop treated assumptions, i t utilized conse rvative EDW Cs derived through EFED modeling which are unlikely to underestimate t he concentration of

dinotefuran in drinking water

. The present DEEM

- FCIDTM analysis assumes that all drinking water will contain dinotefuran at the highest acute E DW C levels modeled by

EFED for ground water or surface water

. For these reasons

, it can be co ncluded that the

DEEM

- FCIDTM analysi s do es not underestimate risk from acute exposure to dinotefuran for the general U

. S

. population and all its subgroups.

The chronic dietary assessment conducted with DEEM

- FCIDTM for dinotefuran is an

unrefined analysis. In addition to tolerance level residues

, default processing factors

, and 100% crop treated assumptions, it utilized conservative EDWCs derived through EFED modeling which are unlikely to underestimate the concentration of dinotefuran in drinking water . Th e present DEEM

- FCIDTM analysis assumes that all drinking water will

contain dinotefuran at the highest chronic EDWC le vels modeled by EFED for ground water or surface water. For these reasons, it can be concluded that the DEEM

FCIDTM analysis does not underestimate ri sk from chronic exposure to dinotefuran for the general U

. S

. population and all its subgroups.

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

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Page 10 of 25 

## VIII. Conclusions

The conservative acute screening

- level dietary risk assessment conducted with DEEM

FCIDTM indicate s that exposure s to dinotefuran are below H ED’s level of concern. The

acute dietary risk to dinotefuran is estimated to be 3.0 % of the aPA D for the general U

. S

. population an d 7.6 % of the aPAD f or the most highly exposed population subgroup

, all

infants

. Therefore, HED does not have any concerns for the propos ed new tolerances of

dinotefuran

.

The conservative chro nic dietary risk assessment conducted with DEEM

- FCIDTM indicates that exposures to dinotefuran are below HED’s level of concern. The chronic dietary risk to di notefuran is estimated to be 1.4 % of the cPAD for the general U

. S

. popu lation and 3.9 % of the cPAD f or the most highly exposed population s u bgroup,

Children 1

- 2 years old. Therefore, HED does not have any concerns for the propos ed new

tolerances of dinotefuran

.

IX. List of Attachments

1. Attachment 1: Acute Dietary Exposure (food + water) Input File.

2. Attachment 2: Acute Dietary Exposur e (food + water) Results File.

3

. Attachment 3 : Chronic Dietary Exposure (food + water) Input File.

4

. Attachment 4 : Chronic Dietary Exposure (food + water) Results File.

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 11 of 25 ATTACHMENT 1

Filename: C: \ Documents and Settings \ cwalls \ My

Documents \ Cassi \ HED \ D inotefuran \ section 3 rice 2012 \ ACUTE FOOD+WATER 082012.R08

Chemical: Dinotefuran RfD(Chronic): .38 mg/kg bw/day NOEL(Chronic): 38 mg/kg bw/day RfD(Acute): 1.25 mg/kg bw/day NOEL(Acute): 125 mg/kg bw/day
Date created/last modified: 08

- 29

- 2012/12:28:46 Program ver. 3.16, 03

- 08

- d Comment: Acute and Chronic Dietary (food+drinking water) Assessment

---------------------------------------------------------------------------------

-- EPA Crop Def Res Adj.Factor s

Comment Code Grp Commodity Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ ------ -----

-- 0103015000 1CD Arrowroot, flour 0.050000 1.000 1.000

01030150 01 1CD Arrowroot, flour

- babyfood 0.050000 1.000 1.000
0103017000 1CD Artichoke, Jerusalem 0.050000 1.000 1.000

0103082000 1CD Cassava 0.050000 1.000 1.000

0103082001 1CD Cassava

- babyfood 0.050000 1.000 1.000
0103139000 1CD Dasheen, corm 0.050000 1.000 1.000 0103166000 1CD Ginger 0.050000 1.000 1.000 0103166001 1CD Ginger

- babyfood 0.05000 0 1.000 1.000 0103167000 1CD Ginger, dried 0.050000 1.000 1.000 0103296000 1C Potato, chips 0.100000 1.000 1.000 0103297000 1C Potato, dry (granules/ flakes) 0.150000 1.000 1.000

010329 7001 1C Potato, dry (granules/ flakes)

- b 0.150000 1.000 1.000
0103298000 1C Potato, flour 0.150000 1.000 1.000
0103298001 1C Potato, flour

- babyfood 0.150000 1.000 1.000
0103299000 1C Potato, tuber, w/peel 0.050000 1.000 1.000 0103299001 1C Potato, tuber, w/peel

- babyfood 0.050000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 0.050000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.050 000 1.000 1.000 0103366000 1CD Sweet potato 0.050000 1.000 1.000 0103366001 1CD Sweet potato

- babyfood 0.050000 1.000 1.000
0103371000 1CD Tanier, corm 0.050000 1.000 1.000

0103 387000 1CD Turmeric 0.050000 1.000 1.000
0103406000 1CD Yam, true 0.050000 1.000 1.000

0103407000 1CD Yam bean 0.050000 1.000 1.000
0301165000 3A Garlic, bulb 0.150000 1.000 1.000
0301165001 3A Garlic, bulb

- babyfood 0.150000 1.000 1.000
0301237000 3A Onion, bulb 0.150000 1.000 1.000
0301237001 3A Onion, bulb

- babyfood 0.1 50000 1.000 1.000
0301238000 3A Onion, bulb, dried 0.150000 9.000 1.000
0301238001 3A Onion, bulb, dried

- babyfood 0.150000 9.000 1.000

0302198000 3B Leek 5.000000 1.000 1.000

03 02239000 3B Onion, green 5.000000 1.000 1.000
0302338500 3B Shallot, fresh leaves 5.000000 1.000 1.000 0401005000 4A Amaranth, leafy 5.000000 1.000 1.000 0401018000 4A Arugula 5.000000 1.000 1.000 0401104000 4A Chrysanthemum, garland 5.000000 1.000 1.000 0401133000 4A Cress, garden 5.000000 1.000 1.000 0401134000 4A Cress, upland 5 .000000 1.000 1.000
0401138000 4A Dandelion, leaves 5.000000 1.000 1.000

0401150000 4A Endive 5.000000 1.000 1.000
0401204000 4A Lettuce, head 5.000000 1.000 1.000
0401205000 4A Lettuce, leaf 5.000000 1.000 1.000 0401248000 4A Parsley, leaves 5.000000 1.000 1.000

0401313000 4A Radicchio 5.000000 1.000 1.000 0401355000 4A Spinach 5.000000 1.000 1.000 0401355001 4A Spinach

- babyfood 5.000000 1.000 1.000

0402076000 4B Cardoon 5.000000 1.000 1.000 0402085000 4B Celery 5.000000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 12 of 25 0402085001 4B Celery

- babyfood 5.000000 1.000 1.000 0402086000 4B Celery, juice 5.000000 1.000 1.000

0402087000 4B Celtuce 5.000000 1.000 1.000
0402152000 4B Fennel, Florence 5.000000 1.000 1.000

0402322000 4B Rhubarb 5.000000 1.000 1.000

0402367000 4B Swiss chard 5.000000 1.000 1.000

0501061000 5A Broccol i 1.400000 1.000 1.000

0501061001 5A Broccoli

- babyfood 1.400000 1.000 1.000
0501062000 5A Broccoli, Chinese 1.400000 1.000 1.000 0501064000 5A Brussels sprouts 1.400000 1.000 1.000 0501069000 5A Cabbage 1.400000 1.000 1.000 0501071000 5A Cabbage, Chinese, napa 1.400000 1.000 1.000 0501072000 5A Cabbage, Chinese, mustard 1.400000 1.000 1.00 0

0501083000 5A Cauliflower 1.400000 1.000 1.000

0501196000 5A Kohlrabi 1.400000 1.000 1.000

0502063000 5B Broccoli raab 15.000000 1.000 1.000

0502070000 5B Cabba ge, Chinese, bok choy 15.000000 1.000 1.000

0502117000 5B Collards 15.000000 1.000 1.000

0502194000 5B Kale 15.000000 1.000 1.000 0502229000 5B Mustard greens 15.000000 1.000 1.000 0502318000 5B Rape greens 15.000000 1.000 1.000 0502389000 5B Turnip, greens 15.000000 1.000 1.000

0801374000 8A Tomatillo 0.700000 1.000 1. 000

0801375000 8A Tomato 0.700000 1.000 1.000

0801375001 8A Tomato

- babyfood 0.700000 1.000 1.000 0801376000 8A Tomato, paste 1.000000 1.000 1.000

0801376001 8A Tom ato, paste

- babyfood 1.000000 1.000 1.000 0801377000 8A Tomato, puree 0.700000 3.300 1.000 0801377001 8A Tomato, puree

- babyfood 0.700000 3.300 1.000
0801378000 8A Tomato, dried 0.700000 14.300 1.000
0801378001 8A Tomato, dried

- babyfood 0.700000 14.300 1.000 0801379000 8A Tomato, juice 0.700000 1.500 1.000 0802148000 8BC Eggplant 0.700000 1.000 1.000 0802270000 8B Pepper, bell 0.700000 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 0.700000 1.000 1.000 0802271000 8B Pepper, bell, dried 0.700000 1.000 1.000

0802271001 8B P epper, bell, dried

- babyfood 0.700000 1.000 1.000 0802272000 8BC Pepper, nonbell 0.700000 1.000 1.000 0802272001 8BC Pepper, nonbell

- babyfood 0.700000 1.000 1.000 0802273000 8BC Pepper, nonbell, dried 0.700000 1.000 1.000 0901075000 9A Cantaloupe 0.500000 1.000 1.000 0901187000 9A Honeydew melon 0.500000 1.000 1.000

0901399000 9A Watermelon 0.500000 1.000 1.000 0901400000 9A Watermelon, juice 0.500000 1.000 1.000 0902021000 9B Balsam pear 0.500000 1.000 1.000 0902088000 9B Chayote, fruit 0.500000 1.000 1.000

0902102000 9B Chinese waxgourd 0.500000 1.000 1.000

0902135000 9B Cucumber 0.500000 1.000 1.000 0902308000 9B Pumpkin 0.500000 1.000 1.000 0902309000 9B Pumpkin, seed 0.500000 1.000 1.000 0902356000 9B Squash, summer 0.500000 1.000 1.000 0902356001 9B Squash, summer

- babyfood 0.500000 1.000 1.000 0902357000 9B Squash, winter 0.500000 1.0 00 1.000 0902357001 9B Squash, winter

- babyfood 0.500000 1.000 1.000 1100007000 11 Apple, fruit with peel 1.000000 1.000 1.000 1100008000 11 Apple, peeled fruit 1.000000 1.000 1.000

1100008001 11 Apple, peeled fruit

- babyfood 1.000000 1.000 1.000 1100009000 11 Apple, dried 1.000000 8.000 1.000 1100009001 11 Apple, dried

- babyfood 1.000000 8.000 1.000 1100010000 11 Apple, juice 1.000000 1.300 1.000 1100010001 11 Apple, juice

- babyfood 1.000000 1.300 1.000 1100011000 11 Apple, sauce 1.000000 1.000 1.000 1100011001 11 Apple, sauce

- babyfood 1.000000 1 .000 1.000 1100129000 11 Crabapple 1.000000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 13 of 25 1100210000 11 Loquat 1.000000 1.000 1.000

1100266000 11 Pear 1.000000 1.000 1.000

1100266001 11 Pear

- babyfood 1.000000 1.000 1.000
1100267000 11 Pear, dried 1.000000 6.250 1.000 1100268000 11 Pear, juice 1.000000 1.000 1.000 1100268001 11 Pear, juice

- babyfood 1.000000 1.000 1.000
1100310000 11 Quince 1.000000 1.000 1.000 1201090000 12A Cherry 1.000000 1.000 1.000 1201090001 12A Cherry

- babyfood 1.000000 1.000 1.000 1201091000 12A Cherry, juice 1.000000 1.500 1.000 1201091001 12A Cherry, juice

- babyfood 1.000000 1.500 1.000 1202012000 12B Apricot 1.000000 1.000 1.000

120201200 1 12B Apricot

- babyfood 1.000000 1.000 1.000 1202013000 12B Apricot, dried 1.000000 6.000 1.000 1202014000 12B Apricot, juice 1.000000 1.000 1.000 1202014001 12B Apricot, juice

- bab yfood 1.000000 1.000 1.000

1202230000 12B Nectarine 1.000000 1.000 1.000

1202260000 12B Peach 1.000000 1.000 1.000

1202260001 12B Peach

- babyfood 1.000000 1.000 1.000
1202261000 12B Peach, dried 1.000000 7.000 1.000
1202261001 12B Peach, dried

- babyfood 1.000000 7.000 1.000 1202262000 12B Peach, juice 1.000000 1.000 1.000

1202262 001 12B Peach, juice

- babyfood 1.000000 1.000 1.000

1203285000 12C Plum 1.000000 1.000 1.000

1203285001 12C Plum

- babyfood 1.000000 1.000 1.000 1203286000 12C Plum, prune, fre sh 1.000000 1.000 1.000 1203286001 12C Plum, prune, fresh

- babyfood 1.000000 1.000 1.000 1203287000 12C Plum, prune, dried 1.000000 5.000 1.000 1203287001 12C Plum, prune, dried

- babyfood 1.0000 00 5.000 1.000 1203288000 12C Plum, prune, juice 1.000000 1.400 1.000 1203288001 12C Plum, prune, juice

- babyfood 1.000000 1.400 1.000 1302057000 13B Blueberry 0.200000 1.000 1.000

13020 57001 13B Blueberry

- babyfood 0.200000 1.000 1.000 1302174000 13B Gooseberry 0.900000 1.000 1.000 1304175000 13D Grape 0.900000 1.000 1.000 1304176000 13D Grape, juice 0.900000 1.200 1.000 1304176001 13D Grape, juice

- babyfood 0.900000 1.200 1.000 1304179000 13D Grape, wine and sherry 0.900000 1.000 1.000 1307130000 13G Cranberry 0.20 0000 1.000 1.000 1307130001 13G Cranberry

- babyfood 0.200000 1.000 1.000 1307131000 13G Cranberry, dried 0.200000 1.000 1.000 1307132000 13G Cranberry, juice 0.200000 1.100 1.000

130 7132001 13G Cranberry, juice

- babyfood 0.200000 1.100 1.000
1500323000 15 Rice, white 9.000000 1.000 1.000
1500323001 15 Rice, white

- babyfood 9.000000 1.000 1.000
1500324000 15 Rice, brown 9.000000 1.000 1.000
1500324001 15 Rice, brown

- babyfood 9.000000 1.000 1.000
1500325000 15 Rice, flour 9.000000 1.000 1.000
1500325001 15 Rice, flour

- babyfood 9. 000000 1.000 1.000
1500326000 15 Rice, bran 9.000000 1.000 1.000
1500326001 15 Rice, bran

- babyfood 9.000000 1.000 1.000
2003128000 20C Cottonseed, oil 0.400000 1.000 1.000

2 003128001 20C Cottonseed, oil

- babyfood 0.400000 1.000 1.000
3100044000 31 Beef, meat 0.050000 1.000 1.000
3100044001 31 Beef, meat

- babyfood 0.050000 1.000 1.000
3100045000 31 Beef, meat , dried 0.050000 1.920 1.000 3100046000 31 Beef, meat byproducts 0.050000 1.000 1.000 3100046001 31 Beef, meat byproducts

- babyfood 0.050000 1.000 1.000
3100047000 31 Beef, fat 0.050000 1.000 1.000
3100047001 31 Beef, fat

- babyfood 0.050000 1.000 1.000 3100048000 31 Beef, kidney 0.050000 1.000 1.000
3100049000 31 Beef, liver 0.050000 1.000 1.000
3100049001 31 Beef, liver

- babyfood 0.050000 1.000 1.000
3200169000 32 Goat, meat 0.050000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 14 of 25 3200170000 32 Goat, meat byproducts 0.050000 1.000 1.000
3200171000 32 Goat, fa t 0.050000 1.000 1.000 3200172000 32 Goat, kidney 0.050000 1.000 1.000
3200173000 32 Goat, liver 0.050000 1.000 1.000
3300189000 33 Horse, meat 0.050000 1.000 1.000
3400290000 34 Pork, meat 0.050000 1.000 1.000
3400290001 34 Pork, meat

- babyfood 0.050000 1.000 1.000
3400291000 34 Pork, skin 0.050000 1.000 1.000 3400292000 34 Pork, meat byproducts 0.050000 1.000 1.000 3400292001 34 Pork, meat byproducts

- babyfood 0.050000 1.000 1.000
3400293000 34 Pork, fat 0.050000 1.000 1.000
3400293001 34 Pork, fat

- babyfood 0.050000 1.000 1.000 3400294000 34 Pork, kidney 0.050000 1.000 1.000
3400295000 34 Pork, liver 0.050000 1.000 1.000 3500339000 35 Sheep, meat 0.050000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.050000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.050000 1.000 1.000 3500341000 35 Sheep, fat 0.050000 1.000 1.0 00 3500341001 35 Sheep, fat

- babyfood 0.050000 1.000 1.000 3500342000 35 Sheep, kidney 0.050000 1.000 1.000 3500343000 35 Sheep, liver 0.050000 1.000 1.000

3600222000 36 Milk , fat 0.050000 1.000 1.000
3600222001 36 Milk, fat

- baby food/infant formu 0.050000 1.000 1.000
3600223000 36 Milk, nonfat solids 0.050000 1.000 1.000
3600223001 36 Milk, nonfat solids

- baby food /in 0.050000 1.000 1.000
3600224000 36 Milk, water 0.050000 1.000 1.000
3600224001 36 Milk, water

- babyfood/infant form 0.050000 1.000 1.000
3600225001 36 Milk, sugar (lactose)

- baby food/ 0.050000 1.000 1 .000 3800221000 38 Meat, game 0.050000 1.000 1.000
3900312000 39 Rabbit, meat 0.050000 1.000 1.000 4000095000 40 Chicken, meat byproducts 0.010000 1.000 1.000

4000095001 40 Ch icken, meat byproducts

- babyfoo 0.010000 1.000 1.000 6000303000 60 Poultry, other, meat byproducts 0.010000 1.000 1.000 7000145000 70 Egg, whole 0.010000 1.000 1.000 7000145001 70 Egg, whole

- babyfood 0.010000 1.000 1.000 7000146000 70 Egg, white 0.010000 1.000 1.000 7000146001 70 Egg, white (solids)

- babyfood 0.010000 1.000 1.000 7000147000 70 Egg, yolk 0.010000 1.000 1.000 7000147001 70 Egg, yolk

- babyfood 0.010000 1.000 1.000
8601000000 86A Water, direct, all sources 0.269000 1.000 1.000
8602000000 86B Water, indirect, all sources 0.269000 1.000 1.000

9500177000 O Grape, leaves 0.900000 1.000 1.000 9500178000 O Grape, raisin 2.500000 1.000 1.000
9500372000 O Tea, dried 50.000000 1.000 1.000

9500398000 O Watercress 8.000000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 15 of 25 ATTACHMENT 2

U.S. EPA Ver. 3.16, 03

- 08

- d

DEEM

- FCID ACUTE Analysis for DINOTEFURAN NHANES 2003

- 2008 2

- Day

Residue file: ACUTE FOOD+WATER 082012.R08 Adjustment factor #2 NOT used. Analysis Date: 08

- 29

- 2012/12:34:49 Residue file dated: 08

- 29

- 2012/12:28:46 NOEL (Acute) = 125.000000 mg/kg body

- wt/day
RAC/FF intake summed over 24 hours
Run Comment: "Acute and Chronic Dietary (food+drinking water) A ssessment "

===============================================================================

Summary calculations

-- per capita:

--- 95th Percentile

---- --- 99th Percentile

---- --- 99.9th Percentile

---- Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE

---------- ------- -------- ---------- ------- -------- ---------- ------- -------- Total US Population:

0.037384 2.99 3343 0.067207 5.38 1859 0.119658 9.57 1044

All Infants:

0.095276 7.62 1311 0.138033 11.04 905 0.227361 18.19 549

Female 13

- 50:

0.030469 2.44 4102 0.044595 3.57 2803 0.069898 5.59 1788

Children 1

- 2:

0.094678 7.57 1320 0.143110 11.45 873 0.205827 16. 47 607

Children 3

- 5:

0.069524 5.56 1797 0.105979 8.48 1179 0.135738 10.86 920

Children 6

- 12:

0.040299 3.22 3101 0.064862 5.19 1927 0.099914 7.99 1251

Youth 13

- 19:

0.026648 2.13 4690 0 .042869 3.43 2915 0.063353 5.07 1973

Adults 20

- 49:

0.031301 2.50 3993 0.047706 3.82 2620 0.073855 5.91 1692

Adults 50

- 99:

0.027932 2.23 4475 0.042925 3.43 2912 0.077277 6.18 1617

Fema le 13

- 49:

0.030602 2.45 4084 0.044730 3.58 2794 0.069415 5.55 1800

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 16 of 25 ATTACHMENT 3

Filename: C: \ Documents and Settings \ cwalls \ My

Documents \ Cassi \ HED \ Dinotefuran \ section 3 rice 2012 \ CHRONIC FOOD+WATER 082012.R08

Chemical: Dinote furan RfD(Chronic): 1 mg/kg bw/day NOEL(Chronic): 99.7 mg/kg bw/day RfD(Acute): 1.25 mg/kg bw/day NOEL(Acute): 125 mg/kg bw/day
Date created/last modified: 08

- 29

- 2012/12:31:14 Program ver. 3.16, 03

- 08

- d Comment: Acute and Chronic Dietary (food+dri nking water) Assessment

---------------------------------------------------------------------------------

-- EPA Crop Def Res Adj.Factors

Comment Code Grp Commodity Name (ppm) #1 #2

---------- ---- ------------------------------- ---------- ------ ------ -----

-- 0101050000 1AB Beet, garden, roots 0.010000 1.000 1.000 0101050001 1AB Beet, garden, roots

- babyfood 0.010000 1.000 1.000

010105 2000 1A Beet, sugar 0.010000 1.000 1.000 0101052001 1A Beet, sugar

- babyfood 0.010000 1.000 1.000 0101053000 1A Beet, sugar, molasses 0.010000 1.000 1.000 0101053001 1A Beet, sugar, mo lasses

- babyfood 0.010000 1.000 1.000

0101067000 1AB Burdock 0.010000 1.000 1.000

0101078000 1AB Carrot 0.010000 1.000 1.000

0101078001 1AB Carrot

- babyfood 0.010 000 1.000 1.000 0101079000 1AB Carrot, juice 0.010000 1.000 1.000

0101084000 1AB Celeriac 0.010000 1.000 1.000 0101100000 1AB Chicory, roots 0.010000 1.000 1.000

0101 168000 1AB Ginseng, dried 0.010000 1.000 1.000

0101190000 1AB Horseradish 0.010000 1.000 1.000 0101250000 1AB Parsley, turnip rooted 0.010000 1.000 1.000 0101251000 1AB Parsnip 0.010000 1.000 1.000 0101251001 1AB Parsnip

- babyfood 0.010000 1.000 1.000
0101314000 1AB Radish, roots 0.010000 1.000 1.000
0101316000 1AB Radish, Oriental, roots 0.0 10000 1.000 1.000 0101327000 1AB Rutabaga 0.010000 1.000 1.000 0101331000 1AB Salsify, roots 0.010000 1.000 1.000 0101388000 1AB Turnip, roots 0.010000 1.000 1.000

01 03015000 1CD Arrowroot, flour 0.050000 1.000 1.000
0103015001 1CD Arrowroot, flour

- babyfood 0.050000 1.000 1.000
0103017000 1CD Artichoke, Jerusalem 0.050000 1.000 1.000

0103082000 1CD Cassava 0.050000 1.000 1.000

0103082001 1CD Cassava

- babyfood 0.050000 1.000 1.000
0103139000 1CD Dasheen, corm 0.050000 1.000 1.000 0103166000 1CD Ginger 0 .050000 1.000 1.000 0103166001 1CD Ginger

- babyfood 0.050000 1.000 1.000 0103167000 1CD Ginger, dried 0.050000 1.000 1.000 0103296000 1C Potato, chips 0.100000 1.000 1.000 0103297000 1C Potato, dry (granules/ flakes) 0.150000 1.000 1.000 0103297001 1C Potato, dry (granules/ flakes)

- b 0.150000 1.000 1.000
0103298000 1C Potato, flour 0.150000 1.000 1.000
0103298001 1C Potato, f lour

- babyfood 0.150000 1.000 1.000 0103299000 1C Potato, tuber, w/peel 0.050000 1.000 1.000 0103299001 1C Potato, tuber, w/peel

- babyfood 0.050000 1.000 1.000 0103300000 1C Potato, tuber, w/o peel 0.050000 1.000 1.000 0103300001 1C Potato, tuber, w/o peel

- babyfood 0.050000 1.000 1.000 0103366000 1CD Sweet potato 0.050000 1.000 1.000 0103366001 1CD Sweet potato

- babyfood 0.050000 1.000 1.000
0103371000 1CD Tanier, corm 0.050000 1.000 1.000

0103387000 1CD Turmeric 0.050000 1.000 1.000
0103406000 1CD Yam, true 0.050000 1.000 1.000

0103407000 1CD Yam bea n 0.050000 1.000 1.000 0200051000 2 Beet, garden, tops 0.010000 1.000 1.000 0200101000 2 Chicory, tops 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 17 of 25 0200140000 2 Dasheen, leaves 0.010000 1.000 1.000 0200315000 2 Radish, tops 0.010000 1.000 1.000 0200317000 2 Radish, Oriental, tops 0.010000 1.000 1.000 0200332000 2 Salsify, tops 0.010000 1.000 1.00 0
0301165000 3A Garlic, bulb 0.150000 1.000 1.000
0301165001 3A Garlic, bulb

- babyfood 0.150000 1.000 1.000
0301237000 3A Onion, bulb 0.150000 1.000 1.000

0301237001 3A Onion , bulb

- babyfood 0.150000 1.000 1.000
0301238000 3A Onion, bulb, dried 0.150000 9.000 1.000
0301238001 3A Onion, bulb, dried

- babyfood 0.150000 9.000 1.000
0301338000 3A Shallot, bulb 0.010000 1.000 1.000
0302103000 3B Chive, fresh leaves 0.010000 1.000 1.000

0302198000 3B Leek 5.000000 1.000 1.000 0302239000 3B Onion, green 5.000000 1.000 1. 000
0302338500 3B Shallot, fresh leaves 5.000000 1.000 1.000 0401005000 4A Amaranth, leafy 5.000000 1.000 1.000 0401018000 4A Arugula 5.000000 1.000 1.000

0401104000 4A Chr ysanthemum, garland 5.000000 1.000 1.000 0401133000 4A Cress, garden 5.000000 1.000 1.000 0401134000 4A Cress, upland 5.000000 1.000 1.000
0401138000 4A Dandelion, leaves 5.000000 1.000 1.000

0401150000 4A Endive 5.000000 1.000 1.000
0401204000 4A Lettuce, head 5.000000 1.000 1.000
0401205000 4A Lettuce, leaf 5.000000 1.000 1.000 0401248000 4A Parsley, leaves 5.000000 1.000 1.000

0401313000 4A Radicchio 5.000000 1.000 1.000 0401355000 4A Spinach 5.000000 1.000 1.000

0401355001 4A S pinach

- babyfood 5.000000 1.000 1.000

0402076000 4B Cardoon 5.000000 1.000 1.000 0402085000 4B Celery 5.000000 1.000 1.000 0402085001 4B Celery

- babyfood 5.000000 1.000 1.000 0402086000 4B Celery, juice 5.000000 1.000 1.000

0402087000 4B Celtuce 5.000000 1.000 1.000
0402152000 4B Fennel, Florence 5.000000 1.000 1.000

0402322000 4B Rhubarb 5.000000 1.000 1.000

0402367000 4B Swiss chard 5.000000 1.000 1.000

0501061000 5A Broccoli 1.400000 1.000 1.000

0501061001 5A Broccoli

- babyfood 1.400000 1.000 1.000
0501062000 5A Broccoli, Chinese 1.400000 1.000 1.000 0501064000 5A Brussels sprouts 1.400000 1.000 1.000 0501069000 5A Cabbage 1.400000 1.000 1.000 0501071000 5A Cabbage, Chinese, napa 1.400000 1.000 1.000 0501072000 5A Cabbage, Chinese, mustard 1.400000 1.000 1.000

0501083000 5A Cauliflower 1.400000 1.0 00 1.000

0501196000 5A Kohlrabi 1.400000 1.000 1.000

0502063000 5B Broccoli raab 15.000000 1.000 1.000 0502070000 5B Cabbage, Chinese, bok choy 15.000000 1.000 1.000

0502117000 5B Collards 15.000000 1.000 1.000

0502194000 5B Kale 15.000000 1.000 1.000 0502229000 5B Mustard greens 15.000000 1.000 1.000 0502318000 5B Rape greens 15.000000 1.000 1.000 0502389000 5B Turnip, greens 15.000000 1.000 1.000 0600347000 6 Soybean, seed 0.010000 1.000 1.000 0600349000 6 Soybean, soy milk 0.010000 1 .000 1.000 0600349001 6 Soybean, soy milk

- babyfood or in 0.010000 1.000 1.000 0600350000 6 Soybean, oil 0.010000 1.000 1.000 0600350001 6 Soybean, oil

- babyfood 0.010000 1.000 1.000

0601043000 6A Bean, snap, succulent 0.010000 1.000 1.000 0601043001 6A Bean, snap, succulent

- babyfood 0.010000 1.000 1.000 0601257000 6A Pea, edible podded, succulent 0.010000 1.000 1.000 0601349500 6AB Soybean, vegetable 0.010000 1.000 1.000
0602031000 6B Bean, broad, succulent 0.010000 1.000 1.000 0602033000 6B Bean, cowpea, succulent 0.010000 1.000 1.000
0602037000 6B Bean, lima, succulent 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 18 of 25 0602255000 6B Pea, succulent 0.010000 1.000 1.000
0602255001 6B Pea, succulent

- babyfood 0.010000 1.000 1.000 0602259000 6B Pea, pigeon, succulent 0.010000 1.000 1.000

060303000 0 6C Bean, black, seed 0.010000 1.000 1.000
0603032000 6C Bean, broad, seed 0.010000 1.000 1.000 0603034000 6C Bean, cowpea, seed 0.010000 1.000 1.000 0603035000 6C Bean, great north ern, seed 0.010000 1.000 1.000 0603036000 6C Bean, kidney, seed 0.010000 1.000 1.000
0603038000 6C Bean, lima, seed 0.010000 1.000 1.000 0603039000 6C Bean, mung, seed 0.010000 1.000 1.000 0603040000 6C Bean, navy, seed 0.010000 1.000 1.000 0603041000 6C Bean, pink, seed 0.010000 1.000 1.000 0603042000 6C Bean, pinto, seed 0.010000 1.000 1.000

0603098 000 6C Chickpea, seed 0.010000 1.000 1.000 0603098001 6C Chickpea, seed

- babyfood 0.010000 1.000 1.000 0603099000 6C Chickpea, flour 0.010000 1.000 1.000
0603182000 6C Guar, seed 0.010000 1.000 1.000
0603182001 6C Guar, seed

- babyfood 0.010000 1.000 1.000
0603203000 6C Lentil, seed 0.010000 1.000 1.000 0603256000 6C Pea, dry 0.0100 00 1.000 1.000 0603256001 6C Pea, dry

- babyfood 0.010000 1.000 1.000 0603258000 6C Pea, pigeon, seed 0.010000 1.000 1.000 0603348000 6C Soybean, flour 0.010000 1.000 1.000

06033 48001 6C Soybean, flour

- babyfood 0.010000 1.000 1.000

0801374000 8A Tomatillo 0.700000 1.000 1.000

0801375000 8A Tomato 0.700000 1.000 1.000

0801375001 8A Tomato

- babyfoo d 0.700000 1.000 1.000 0801376000 8A Tomato, paste 1.000000 1.000 1.000 0801376001 8A Tomato, paste

- babyfood 1.000000 1.000 1.000 0801377000 8A Tomato, puree 0.70 0000 3.300 1.000 0801377001 8A Tomato, puree

- babyfood 0.700000 3.300 1.000
0801378000 8A Tomato, dried 0.700000 14.300 1.000
0801378001 8A Tomato, dried

- babyfood 0.700000 14.300 1.000

080 1379000 8A Tomato, juice 0.700000 1.500 1.000
0801380000 8A Tomato, Tree 0.010000 1.000 1.000 0802148000 8BC Eggplant 0.700000 1.000 1.000

0802234000 8BC Okra 0.010000 1.000 1.000 0802270000 8B Pepper, bell 0.700000 1.000 1.000 0802270001 8B Pepper, bell

- babyfood 0.700000 1.000 1.000 0802271000 8B Pepper, bell, dried 0. 700000 1.000 1.000 0802271001 8B Pepper, bell, dried

- babyfood 0.700000 1.000 1.000 0802272000 8BC Pepper, nonbell 0.700000 1.000 1.000 0802272001 8BC Pepper, nonbell

- babyfood 0.700000 1.000 1.000

0 802273000 8BC Pepper, nonbell, dried 0.700000 1.000 1.000 0901075000 9A Cantaloupe 0.500000 1.000 1.000 0901187000 9A Honeydew melon 0.500000 1.000 1.000

0901399000 9A Watermelon 0.500000 1.000 1.000 0901400000 9A Watermelon, juice 0.500000 1.000 1.000 0902021000 9B Balsam pear 0.500000 1.000 1.000 0902088000 9B Chayote, fruit 0.500000 1.000 1.000 0902102000 9B Chinese waxgourd 0.500000 1.000 1.000

0902135000 9B Cucumber 0.500000 1.000 1.000 0902308000 9B Pumpkin 0.500000 1.000 1.000 0902309000 9B Pumpkin, seed 0.500000 1.000 1.000 0902356000 9B Squash, summer 0.500000 1.000 1.000 0902356001 9B Squash, summer

- babyfood 0.500000 1.000 1.000 0902357000 9B Squash, winter 0.500000 1.000 1.000 0902357001 9B Squash, winter

- babyfood 0.500000 1.000 1.000

1001106000 10A Citron 0.010000 1.000 1.000 1001107000 10A Citrus hybrids 0.010000 1.000 1.000
1001108000 10A Citrus, oil 0.010000 1.000 1.000 1001240000 10A Orange 0.010000 1.000 1.000 1001241000 10A Orange, juice 0.010000 1.000 1.000 1001241001 10A Orange, juice

- babyfood 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 19 of 25 1001242000 10A Orange, peel 0.010000 1.000 1.000 1001369000 10A Tangerine 0.010000 1.000 1.000 1001370000 10A Tanger ine, juice 0.010000 1.000 1.000 1002197000 10B Kumquat 0.010000 1.000 1.000

1002199000 10B Lemon 0.010000 1.000 1.000 1002200000 10B Lemon, juice 0.010000 1.000 1.000 1002200001 10B Lemon, juice

- babyfood 0.010000 1.000 1.000 1002201000 10B Lemon, peel 0.010000 1.000 1.000

1002206000 10B Lime 0.010000 1.000 1.0 00 1002207000 10B Lime, juice 0.010000 1.000 1.000 1002207001 10B Lime, juice

- babyfood 0.010000 1.000 1.000 1003180000 10C Grapefruit 0.010000 1.000 1.000 1003181000 10C Grap efruit, juice 0.010000 1.000 1.000

1003307000 10C Pummelo 0.010000 1.000 1.000 1100007000 11 Apple, fruit with peel 1.000000 1.000 1.000 1100008000 11 Apple, peeled fruit 1.000000 1.000 1.000 1100008001 11 Apple, peeled fruit

- babyfood 1.000000 1.000 1.000 1100009000 11 Apple, dried 1.000000 8.000 1.000 1100009001 11 Apple, dried

- babyfood 1.000000 8.000 1 .000 1100010000 11 Apple, juice 1.000000 1.300 1.000 1100010001 11 Apple, juice

- babyfood 1.000000 1.300 1.000 1100011000 11 Apple, sauce 1.000000 1.000 1.000 1100011001 11 Ap ple, sauce

- babyfood 1.000000 1.000 1.000 1100129000 11 Crabapple 1.000000 1.000 1.000 1100173500 11 Goji berry 0.010000 1.000 1.000 1100210000 11 Loquat 1.000000 1.000 1.000

1100266000 11 Pear 1.000000 1.000 1.000

1100266001 11 Pear

- babyfood 1.000000 1.000 1.000
1100267000 11 Pear, dried 1.000000 6.250 1.000 1100268000 11 Pear, juice 1.000000 1.000 1.000 1100268001 11 Pear, juice

- babyfood 1.000000 1.000 1.000
1100310000 11 Quince 1.000000 1.000 1.000

1201090000 12A Cherry 1.000000 1.000 1.000 1201090001 12A Cherry

- babyfood 1.000000 1.000 1.000 1201091000 12A Cherry, juice 1.000000 1.500 1.000 1201091001 12A Cherry, juice

- babyfood 1.000000 1.500 1.000 1202012000 12B Apricot 1.000000 1.000 1.000 1202012001 12B Apricot

- babyfood 1.000000 1.000 1.000 1202013000 12B Apricot, dried 1.000000 6.00 0 1.000 1202014000 12B Apricot, juice 1.000000 1.000 1.000 1202014001 12B Apricot, juice

- babyfood 1.000000 1.000 1.000

1202230000 12B Nectarine 1.000000 1.000 1.000

1202260000 12B Peach 1.000000 1.000 1.000

1202260001 12B Peach

- babyfood 1.000000 1.000 1.000
1202261000 12B Peach, dried 1.000000 7.000 1.000
1202261001 12B Peach, dried

- babyfood 1.000000 7.000 1.000 1202262000 12B Peach, juice 1.000000 1.000 1.000 1202262001 12B Peach, juice

- babyfood 1.000000 1.000 1.000

1203285000 12C Plum 1.000000 1. 000 1.000

1203285001 12C Plum

- babyfood 1.000000 1.000 1.000 1203286000 12C Plum, prune, fresh 1.000000 1.000 1.000 1203286001 12C Plum, prune, fresh

- babyfood 1.000000 1.000 1.000

1203287000 1 2C Plum, prune, dried 1.000000 5.000 1.000 1203287001 12C Plum, prune, dried

- babyfood 1.000000 5.000 1.000 1203288000 12C Plum, prune, juice 1.000000 1.400 1.000 1203288001 12C Plum, prune, juice

- ba byfood 1.000000 1.400 1.000 1301055000 13A Blackberry 0.010000 1.000 1.000 1301056000 13A Blackberry, juice 0.010000 1.000 1.000 1301056001 13A Blackberry, juice

- babyfood 0.010000 1.000 1.000 1301058000 13A Boysenberry 0.010000 1.000 1.000 1301208000 13A Loganberry 0.010000 1.000 1.000 1301320000 13A Raspberry 0.010000 1.000 1.000

1301320001 13A Raspberry

- babyfood 0.010000 1.000 1.000 1301321000 13A Raspberry, juice 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 20 of 25 1301321001 13A Raspberry, juice

- babyfood 0.010000 1.000 1.000 1302057000 13B Blueberry 0.200000 1.000 1.000 1302057001 13B Blueberry

- babyfood 0.200000 1.000 1.000

1302136000 13B Currant 0.010000 1.000 1.000
1302137000 13B Currant, dried 0.010000 1.000 1.000 1302149000 13B Elderberry 0.010000 1.000 1.000 1302174000 13B Gooseberry 0.900000 1.000 1.000 1302191000 13B Huckleberry 0.010000 1.000 1.000

13032270 00 13C Mulberry 0.010000 1.000 1.000 1304175000 13D Grape 0.900000 1.000 1.000 1304176000 13D Grape, juice 0.900000 1.200 1.000 1304176001 13D Grape, juice

- baby food 0.900000 1.200 1.000 1304179000 13D Grape, wine and sherry 0.900000 1.000 1.000 1304195000 13D Kiwifruit, fuzzy 0.010000 1.000 1.000 1307130000 13G Cranberry 0.20000 0 1.000 1.000 1307130001 13G Cranberry

- babyfood 0.200000 1.000 1.000 1307131000 13G Cranberry, dried 0.200000 1.000 1.000 1307132000 13G Cranberry, juice 0.200000 1.100 1.000

130713 2001 13G Cranberry, juice

- babyfood 0.200000 1.100 1.000 1307359000 13G Strawberry 0.010000 1.000 1.000 1307359001 13G Strawberry

- babyfood 0.010000 1.000 1.000 1307360000 13G Strawberry, jui ce 0.010000 1.000 1.000 1307360001 13G Strawberry, juice

- babyfood 0.010000 1.000 1.000

1400003000 14 Almond 0.010000 1.000 1.000

1400003001 14 Almond

- babyfood 0.010 000 1.000 1.000
1400004000 14 Almond, oil 0.010000 1.000 1.000
1400004001 14 Almond, oil

- babyfood 0.010000 1.000 1.000

1400059000 14 Brazil nut 0.010000 1.000 1.000

1400 068000 14 Butternut 0.010000 1.000 1.000

1400081000 14 Cashew 0.010000 1.000 1.000

1400092000 14 Chestnut 0.010000 1.000 1.000

1400155000 14 Hazelnut 0.010000 1.000 1.000
1400156000 14 Hazelnut, oil 0.010000 1.000 1.000 1400185000 14 Hickory nut 0.010000 1.000 1.000

1400213000 14 Macadamia nut 0.0 10000 1.000 1.000

1400269000 14 Pecan 0.010000 1.000 1.000

1400278000 14 Pine nut 0.010000 1.000 1.000

1400282000 14 Pistachio 0.010000 1.000 1.000

14 00391000 14 Walnut 0.010000 1.000 1.000 1500025000 15 Barley, pearled barley 0.010000 1.000 1.000 1500025001 15 Barley, pearled barley

- babyfood 0.010000 1.000 1.000 1500026000 15 Barley, flo ur 0.010000 1.000 1.000 1500026001 15 Barley, flour

- babyfood 0.010000 1.000 1.000 1500027000 15 Barley, bran 0.010000 1.000 1.000

1500065000 15 Buckwheat 0 .010000 1.000 1.000
1500066000 15 Buckwheat, flour 0.010000 1.000 1.000
1500120000 15 Corn, field, flour 0.010000 1.000 1.000
1500120001 15 Corn, field, flour

- babyfood 0.010000 1.000 1.000
1500121000 15 Corn, field, meal 0.010000 1.000 1.000
1500121001 15 Corn, field, meal

- babyfood 0.010000 1.000 1.000
1500122000 15 Corn, field, bran 0.010000 1.000 1.000
1500123000 15 Corn, fie ld, starch 0.010000 1.000 1.000
1500123001 15 Corn, field, starch

- babyfood 0.010000 1.000 1.000 1500124000 15 Corn, field, syrup 0.010000 1.000 1.000 1500124001 15 Corn, field, syrup

- babyfood 0.010000 1.000 1.000
1500125000 15 Corn, field, oil 0.010000 1.000 1.000
1500125001 15 Corn, field, oil

- babyfood 0.010000 1.000 1.000 1500126000 15 Corn, pop 0.010000 1.000 1.000
1500127000 15 Corn, sweet 0.010000 1.000 1.000
1500127001 15 Corn, sweet

- babyfood 0.010000 1.000 1.000 1500226000 15 Millet, grain 0.010000 1.000 1.000
1500231000 15 Oat, br an 0.010000 1.000 1.000
1500232000 15 Oat, flour 0.010000 1.000 1.000
1500232001 15 Oat, flour

- babyfood 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 21 of 25 1500233000 15 Oat, groats/rolled oats 0.010000 1.000 1.000 1500233001 15 Oat, groats/rolled oats

- babyfood 0.010000 1.000 1.000
1500323000 15 Rice, white 9.000000 1.000 1.000
1500323001 15 Rice, white

- babyfood 9.000000 1.000 1.00 0
1500324000 15 Rice, brown 9.000000 1.000 1.000
1500324001 15 Rice, brown

- babyfood 9.000000 1.000 1.000
1500325000 15 Rice, flour 9.000000 1.000 1.000
1500325001 15 Rice, flour

- babyfood 9.000000 1.000 1.000
1500326000 15 Rice, bran 9.000000 1.000 1.000
1500326001 15 Rice, bran

- babyfood 9.000000 1.000 1.000 1500328000 15 Rye, grain 0.010000 1.000 1.000 1500329000 15 Rye, flour 0.010000 1.000 1.000 1500344000 15 Sorghum, grain 0.010000 1.000 1.000 1500345000 15 Sorghum, syrup 0.010000 1.000 1. 000
1500381000 15 Triticale, flour 0.010000 1.000 1.000
1500381001 15 Triticale, flour

- babyfood 0.010000 1.000 1.000 1500401000 15 Wheat, grain 0.010000 1.000 1.000

1500401001 15 Whe at, grain

- babyfood 0.010000 1.000 1.000
1500402000 15 Wheat, flour 0.010000 1.000 1.000
1500402001 15 Wheat, flour

- babyfood 0.010000 1.000 1.000 1500403000 15 Wheat, germ 0.010000 1.000 1.000
1500404000 15 Wheat, bran 0.010000 1.000 1.000

1500405000 15 Wild rice 0.010000 1.000 1.000
1800002000 18 Alfalfa, seed 0.010000 1.000 1.000
1901028000 19A Basil, fresh leaves 0.010000 1.000 1.000
1901028001 19A Basil, fresh leaves

- babyfood 0.010000 1.000 1.000
1901029000 19A Basil, dried leaves 0.010000 1.000 1.000

1901029001 19A B asil, dried leaves

- babyfood 0.010000 1.000 1.000
1901102500 19A Chive, dried leaves 0.010000 1.000 1.000
1901118000 19A Cilantro, leaves 0.010000 1.000 1.000
1901118001 19A Cilantro, leaves

- babyfood 0.010000 1.000 1.000

1901144000 19A Dillweed 0.010000 1.000 1.000
1901184000 19A Herbs, other 0.010000 1.000 1.000
1901184001 19A Herbs, other

- babyfood 0.010000 1.000 1.000 1901202000 19A Lemongrass 0.010000 1.000 1.000 1901220000 19A Marjoram 0.010000 1.000 1.000 1901220001 19A Marjoram

- babyfood 0.010000 1.000 1.000

1901249000 19A Parsley, dried leaves 0.010000 1.000 1.000 1901249001 19A Parsley, dried leaves

- babyfood 0.010000 1.000 1.000 1901334000 19A Savory 0.010000 1.000 1.000

1902105000 19B Cinnamon 0.010000 1.000 1.000

1902105001 19B Cinnamon

- babyfood 0.010000 1.000 1.000
1902119000 19B Coriander, seed 0.010000 1.000 1.000
1902119001 19B Coriander, seed

- babyfood 0.010000 1.0 00 1.000
1902143000 19B Dill, seed 0.010000 1.000 1.000 1902274000 19B Pepper, black and white 0.010000 1.000 1.000 1902274001 19B Pepper, black and white

- babyfood 0.010000 1.000 1.000

1902354000 19 B Spices, other 0.010000 1.000 1.000 1902354001 19B Spices, other

- babyfood 0.010000 1.000 1.000
2001163000 20A Flax seed, oil 0.010000 1.000 1.000 2001319000 20A Rapeseed, oil 0.010000 1.000 1.000 2001319001 20A Rapeseed, oil

- babyfood 0.010000 1.000 1.000
2001336000 20A Sesame, seed 0.010000 1.000 1.000
2001336001 20A Sesame, seed

- babyfood 0.010000 1 .000 1.000
2001337000 20A Sesame, oil 0.010000 1.000 1.000
2001337001 20A Sesame, oil

- babyfood 0.010000 1.000 1.000
2002330000 20B Safflower, oil 0.010000 1.000 1.000

2002330001 20B Safflower, oil

- babyfood 0.010000 1.000 1.000
2002364000 20B Sunflower, seed 0.010000 1.000 1.000
2002365000 20B Sunflower, oil 0.010000 1.000 1.000
2002365001 20B Sunflower, oil

- babyf ood 0.010000 1.000 1.000
2003114001 20C Coconut, oil

- babyfood 0.010000 1.000 1.000
2003128000 20C Cottonseed, oil 0.400000 1.000 1.000
2003128001 20C Cottonseed, oil

- babyfood 0.400000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 22 of 25 2100228000 21 Mushroom 0.010000 1.000 1.000
3100044000 31 Beef, meat 0.050000 1.000 1.000
3100044001 31 Beef, meat

- babyfood 0.050000 1.000 1.000

310004500 0 31 Beef, meat, dried 0.050000 1.920 1.000 3100046000 31 Beef, meat byproducts 0.050000 1.000 1.000 3100046001 31 Beef, meat byproducts

- babyfood 0.050000 1.000 1.000
3100047000 31 Beef, fat 0.050000 1.000 1.000
3100047001 31 Beef, fat

- babyfood 0.050000 1.000 1.000 3100048000 31 Beef, kidney 0.050000 1.000 1.000
3100049000 31 Beef, liver 0.050000 1.000 1.000
3100049001 31 Beef, liver

- babyfood 0.050000 1.000 1.000
3200169000 32 Goat, meat 0.050000 1.000 1.000 3200170000 32 Goat, meat byproducts 0.050000 1.000 1.000

3200171 000 32 Goat, fat 0.050000 1.000 1.000 3200172000 32 Goat, kidney 0.050000 1.000 1.000
3200173000 32 Goat, liver 0.050000 1.000 1.000
3300189000 33 Horse, meat 0.050000 1.000 1.000
3400290000 34 Pork, meat 0.050000 1.000 1.000
3400290001 34 Pork, meat

- babyfood 0.050000 1.000 1.000
3400291000 34 Pork, skin 0.0500 00 1.000 1.000 3400292000 34 Pork, meat byproducts 0.050000 1.000 1.000 3400292001 34 Pork, meat byproducts

- babyfood 0.050000 1.000 1.000
3400293000 34 Pork, fat 0.050000 1.000 1.000

34002 93001 34 Pork, fat

- babyfood 0.050000 1.000 1.000 3400294000 34 Pork, kidney 0.050000 1.000 1.000
3400295000 34 Pork, liver 0.050000 1.000 1.000 3500339000 35 Sheep, meat 0.050000 1.000 1.000 3500339001 35 Sheep, meat

- babyfood 0.050000 1.000 1.000 3500340000 35 Sheep, meat byproducts 0.050000 1.000 1.000 3500341000 35 Sheep, fat 0.05 0000 1.000 1.000 3500341001 35 Sheep, fat

- babyfood 0.050000 1.000 1.000 3500342000 35 Sheep, kidney 0.050000 1.000 1.000 3500343000 35 Sheep, liver 0.050000 1.000 1.000

360 0222000 36 Milk, fat 0.050000 1.000 1.000
3600222001 36 Milk, fat

- baby food/infant formu 0.050000 1.000 1.000
3600223000 36 Milk, nonfat solids 0.050000 1.000 1.000
3600223001 36 Milk, nonfat solids

- baby food/in 0.050000 1.000 1.000
3600224000 36 Milk, water 0.050000 1.000 1.000
3600224001 36 Milk, water

- babyfood/infant form 0.050000 1.000 1.000
3600225001 36 Milk, sugar (lactose)

- baby food/ 0. 050000 1.000 1.000 3800221000 38 Meat, game 0.050000 1.000 1.000
3900312000 39 Rabbit, meat 0.050000 1.000 1.000
4000093000 40 Chicken, meat 0.010000 1.000 1.000

4 000093001 40 Chicken, meat

- babyfood 0.010000 1.000 1.000
4000094000 40 Chicken, liver 0.010000 1.000 1.000 4000095000 40 Chicken, meat byproducts 0.010000 1.000 1.000
4000095001 40 Chicken, m eat byproducts

- babyfoo 0.010000 1.000 1.000
4000096000 40 Chicken, fat 0.010000 1.000 1.000
4000096001 40 Chicken, fat

- babyfood 0.010000 1.000 1.000
4000097000 40 Chicken, skin 0.010000 1.000 1.000
4000097001 40 Chicken, skin

- babyfood 0.010000 1.000 1.000 5000382000 50 Turkey, meat 0.010000 1.000 1.000 5000382001 50 Turkey, meat

- babyfood 0.010000 1.000 1.000 5000383000 50 Turkey, liver 0.010000 1.000 1.000 5000383001 50 Turkey, liver

- babyfood 0.010000 1.000 1.000 5000384000 50 Turkey, meat byproducts 0.010000 1.000 1.000 5000384001 50 Turkey, meat byproducts

- babyfood 0.010000 1.000 1.000 5000385000 50 Turkey, fat 0.010000 1.000 1.000 5000385001 50 Turkey, fat

- babyfood 0.010000 1.000 1.000 5000386000 50 Turkey, skin 0.010000 1.000 1.000 5000386001 50 Turkey, skin

- babyfood 0.010000 1.000 1.000 6000301000 60 Poultry, other, meat 0.010000 1.000 1.000 6000302000 60 Poultry, other, liver 0.010000 1.000 1.000 6000303000 60 Poultry, other, meat byproducts 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 23 of 25 6000304000 60 Poultry, other, fat 0.010000 1.000 1.000 6000305000 60 Poultry, other, skin 0.010000 1.000 1.000 7000145000 70 Egg, w hole 0.010000 1.000 1.000 7000145001 70 Egg, whole

- babyfood 0.010000 1.000 1.000 7000146000 70 Egg, white 0.010000 1.000 1.000 7000146001 70 Egg, white (solids)

- babyfood 0.010000 1.000 1.000 7000147000 70 Egg, yolk 0.010000 1.000 1.000 7000147001 70 Egg, yolk

- babyfood 0.010000 1.000 1.000

8000157000 80 Fish

- freshwater finfish 0.010000 1.000 1.0 00

8000158000 80 Fish

- freshwater finfish, farm ra 0.010000 1.000 1.000

8000159000 80 Fish

- saltwater finfish, tuna 0.010000 1.000 1.000

8000160000 80 Fish

- saltwater finfish, other 0.010000 1.000 1.000

8000161000 80 Fish

- shellfish, crustacean 0.010000 1.000 1.000

8000162000 80 Fish

- shellfish, mollusc 0.010000 1.000 1.000
8601000000 86A Water, direct, all sources 0.257000 1.000 1.000
8602000000 86B Water, indirect, all sources 0.257000 1.000 1.000 9500000500 O Acai berry 0.010000 1.000 1.000

9500001000 O Acerola 0.010000 1.000 1.000 9500001500 O Agave 0.010000 1.000 1 .000 9500006000 O Amaranth, grain 0.010000 1.000 1.000 9500016000 O Artichoke, globe 0.010000 1.000 1.000 9500019000 O Asparagus 0.010000 1.000 1.000

9500019500 O At emoya 0.010000 1.000 1.000

9500020000 O Avocado 0.010000 1.000 1.000
9500022000 O Bamboo, shoots 0.010000 1.000 1.000

9500023000 O Banana 0.010000 1.000 1.000

9500023001 O Banana

- babyfood 0.010000 1.000 1.000
9500024000 O Banana, dried 0.010000 1.000 1.000
9500024001 O Banana, dried

- babyfood 0.010000 1.000 1.000 9500054000 O Belgium endive 0.010000 1.000 1.000

9500060000 O Breadfruit 0.010000 1.000 1.000

9500073000 O Cactus 0.010000 1.000 1.000

9500074000 O Canistel 0.010000 1.000 1.000

9500077000 O Carob 0.010000 1.000 1.000 9500089000 O Cherimoya 0.010000 1.000 1.000
9500109000 O Cocoa bean, chocolate 0.010000 1.000 1.000 9500110000 O Cocoa bean, powder 0.010000 1.000 1.000
9500111000 O Coconut, meat 0.010000 1.000 1.000
9500111001 O Coconut, meat

- babyfood 0.010000 1.00 0 1.000
9500112000 O Coconut, dried 0.010000 1.000 1.000
9500113000 O Coconut, milk 0.010000 1.000 1.000
9500114000 O Coconut, oil 0.010000 1.000 1.000

9500115000 O Coffee, roasted bean 0.010000 1.000 1.000
9500116000 O Coffee, instant 0.010000 1.000 1.000

9500141000 O Date 0.010000 1.000 1.000 9500151000 O Feijoa 0.010000 1.000 1.000 9500153000 O Fig 0.010000 1.000 1.000 9500154000 O Fig, dried 0.010000 1.000 1.000 9500177000 O Grape, leaves 0.900000 1. 000 1.000 9500178000 O Grape, raisin 2.500000 1.000 1.000

9500183000 O Guava 0.010000 1.000 1.000

9500183001 O Guava

- babyfood 0.010000 1.000 1.000

9500186000 O Honey 0.010000 1.000 1.000 9500186001 O Honey

- babyfood 0.010000 1.000 1.000 9500188000 O Hop 0.010000 1.000 1.000

9500193000 O Jackfruit 0.010000 1.000 1.000 9500209000 O Longan 0.010000 1.000 1.000 9500211000 O Lychee 0.010000 1.000 1.000 9500212000 O Lychee, dried 0.010000 1.000 1.000 9500214000 O Mamey apple 0.010000 1.000 1.000 9500215000 O Mango 0.010000 1.000 1.000 9500215001 O Mango

- babyfood 0.010000 1.000 1.000

9500216000 O Mango, dried 0.010000 1.000 1.000 9500217000 O Mango, juice 0.010000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 24 of 25 9500217001 O Mango, juice

- babyfood 0.010000 1.000 1.000 9500218000 O Maple, sugar 0.010000 1.000 1.000 9500219000 O Maple syrup 0.010000 1.000 1.000

9500235000 O Olive 0.010000 1.000 1.000
9500236000 O Olive, oil 0.010000 1.000 1.000
9500243000 O Palm heart, leaves 0.010000 1.000 1.000
9500244000 O Palm, oil 0.010000 1.000 1.000
9500244001 O Palm, oil

- babyfood 0.010000 1.000 1.000

95002450 00 O Papaya 0.010000 1.000 1.000 9500245001 O Papaya

- babyfood 0.010000 1.000 1.000 9500246000 O Papaya, dried 0.010000 1.000 1.000 9500247000 O Papaya, juice 0.010000 1.000 1.000

9500252000 O Passionfruit 0.010000 1.000 1.000

9500252001 O Passionfruit

- babyfood 0.010000 1.000 1.000 9500253000 O Passionfruit, juice 0.01000 0 1.000 1.000 9500253001 O Passionfruit, juice

- babyfood 0.010000 1.000 1.000 9500254000 O Pawpaw 0.010000 1.000 1.000

9500263000 O Peanut 0.010000 1.000 1.000

950026 4000 O Peanut, butter 0.010000 1.000 1.000
9500265000 O Peanut, oil 0.010000 1.000 1.000 9500275000 O Peppermint 0.010000 1.000 1.000 9500276000 O Peppermint, oil 0.010000 1.000 1.000

9500277000 O Persimmon 0.010000 1.000 1.000 9500279000 O Pineapple 0.010000 1.000 1.000 9500279001 O Pineapple

- babyfood 0.010 000 1.000 1.000 9500280000 O Pineapple, dried 0.010000 1.000 1.000 9500281000 O Pineapple, juice 0.010000 1.000 1.000 9500281001 O Pineapple, juice

- babyfood 0.010000 1.000 1.000

9500 283000 O Plantain 0.010000 1.000 1.000
9500284000 O Plantain, dried 0.010000 1.000 1.000 9500289000 O Pomegranate 0.010000 1.000 1.000 9500306000 O Psyllium, see d 0.010000 1.000 1.000 9500311000 O Quinoa, grain 0.010000 1.000 1.000 9500333000 O Sapote, Mamey 0.010000 1.000 1.000

9500335000 O Seaweed 0.0 10000 1.000 1.000

9500335001 O Seaweed

- babyfood 0.010000 1.000 1.000 9500346000 O Soursop 0.010000 1.000 1.000 9500351000 O Spanish lime 0.010000 1.000 1.000

95 00352000 O Spearmint 0.010000 1.000 1.000 9500353000 O Spearmint, oil 0.010000 1.000 1.000

9500358000 O Starfruit 0.010000 1.000 1.000 9500361000 O Sugar apple 0.010000 1.000 1.000 9500362000 O Sugarcane, sugar 0.010000 1.000 1.000 9500362001 O Sugarcane, sugar

- babyfood 0.010000 1.000 1.000 9500363000 O Sugarcane, molasses 0.010000 1.000 1.000 9500363001 O Sugarcane, molasses

- babyfood 0.010000 1.000 1.000

9500368000 O Tamarind 0.010000 1.000 1.000
9500372000 O Tea, drie d 50.000000 1.000 1.000
9500373000 O Tea, instant 0.010000 1.000 1.000
9500373500 O Teff, flour 0.010000 1.000 1.000 9500390000 O Vinegar 0.010000 1.000 1.000

9500397000 O Water chestnut 0.010000 1.000 1.000

9500398000 O Watercress 8.000000 1.000 1.000

### Dinotefuran Dietary Exposure and Risk Assessment DP Number: 398050

PC Code: 044312

____ __________________________________________________________________________________

Page 25 of 25 ATTACHMENT 4

U.S. EPA Ver. 3.16, 03

- 08

- d

DEEM

- FCID Chronic analysis for DINOTEFURAN NHANES 2003

- 2008 2

- day

Residue file name: C: \ Documents and Settings \ cwalls \ My

Documents \ Cassi \ HED \ Dinotefuran \ section 3 rice 2012 \ CHRONIC FOOD+WATER 082012.R08 Adjustment factor #2 NOT used. Analysis Date 08

- 29

- 2012/12:32:59 Residue file dated: 08

- 29

- 2012/12:31:14 Reference dose (RfD, Chronic) = 1 mg/kg bw/day
COMMENT 1: Acute and Chronic Dietary (food+drinking water) Assess ment

=============================================================================== Total exposure by population subgroup

-------------------------------------------------------------------------------

Total Exposure

----------------------------------- Population mg/kg Percent of Subgroup body wt/day R fd

-------------------------------------- ------------- ---------------- Total US Population 0.014212 1.4% Hispanic 0.015500 1.6%

Non

- Hisp

- White 0.013571 1.4%

Non

- Hisp

- Black 0.013486 1.3%

Non

- Hisp

- Other 0.021194 2.1% Nursing Infants 0.018379 1.8%

Non

- Nursing Infants 0.043299 4.3%

Female 13+ PREG 0.012678 1.3%

Children 1

- 6 0.030478 3.0%

Children 7

- 12 0.014299 1.4%

Male 13

- 19 0.009684 1.0%

Female 13

- 19/NP 0.010287 1.0%

Male 20+ 0.01 2390 1.2%
Female 20+/NP 0.012595 1.3%

Seniors 55+ 0.011767 1.2%

All Infants 0.035606 3.6%

Female 1 3

- 50 0.012224 1.2%

Children 1

- 2 0.038570 3.9%

Children 3

- 5 0.027569 2.8%

Children 6

- 12 0.015393 1.5%

Youth 13

- 19 0.009989 1.0%

Adults 20

- 49 0.012827 1.3%

Adults 50

- 99 0.012054 1.2%

Fe male 13

- 49 0.012242 1.2%

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