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Exhibit 10.19    
    


         

  


EMPLOYEE CONFIDENTIALITY, NON-COMPETITION, AND

PROPRIETARY INFORMATION AGREEMENT


        AGREEMENT,
effective as of                        , between Sirtris Pharmaceuticals, Inc., a Delaware corporation (the "Company"),
and                        (the "Employee"). 



        1.     Employee
will make full and prompt disclosure to the Company of all inventions, improvements, modifications, discoveries, methods, technologies, biological materials, and
developments, and all other materials, items, techniques, and ideas related directly or indirectly to the business of the Company (all of which are collectively termed "Intellectual Property"
hereinafter), whether patentable or not, made or conceived by Employee or under Employee's direction during Employee's employment with the Company, whether or not made or conceived during normal
working hours, or on the premises of the Company. 


        2.     Employee
agrees that all Intellectual Property, as defined above, shall be the sole property of the Company and its assigns, and the Company and its assigns shall be the
sole owner of all patents and other rights in connection therewith. Employee hereby assigns to the Company any rights Employee may have or acquire in all Intellectual Property and all related patents,
copyrights, trademarks, trade names, and other industrial and intellectual property rights and applications therefore, in the United States and elsewhere. Employee further agrees that with regard to
all future developments of Intellectual Property, Employee will assist the Company in every way that may be reasonably required by the Company (and at the Company's expense) to obtain and, from time
to time, enforce patents on Intellectual Property in any and all countries that the Company may require, and to that end, Employee will execute all documents for use in applying for and obtaining such
patents thereon and enforcing the same, as the Company may desire, together with any assignment thereof to the Company or persons designated by the Company, and Employee hereby appoints the Company as
Employee's attorney to execute and deliver any such documents or assignments requested by the Company. Employee's obligation to assist the Company in obtaining and enforcing patents for Intellectual
Property in any and all countries shall continue beyond the termination of Employee's employment with the Company, but the Company shall compensate Employee at a reasonable, standard hourly rate
following such termination for time directly spent by Employee at the Company's request for such assistance. 


        3.     Employee
hereby represents that Employee has no continuing obligation to assign to any former employer or any other person, corporation, institution, or firm any
Intellectual Property as described above. Employee represents that Employee's performance of all the terms of this Agreement and as an employee of the Company does not and will not breach any
agreement to keep in confidence proprietary information acquired by Employee, in confidence or in trust, prior to Employee's employment by the Company. Employee has not entered into, and Employee
agrees not to enter into, any agreement (either written or oral), which would put Employee in conflict with this Agreement. 


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        4.     Employee
agrees to assign to the Company any and all copyrights and reproduction rights to any material prepared by Employee in connection with this Agreement and/or
developed during the term of Employee's employment with the Company. 



        5.     Employee
understands and agrees that a condition of Employee's employment and continued employment with the Company is that Employee has not brought and will not bring to
the Company or use in the performance of Employee's duties at the Company any materials or documents rightfully belonging to a former employer which are not generally available to the public. Employee
may bring such materials and documents to the Company only to the extent that Employee has obtained written authorization from such former employer for their possession and use. Accordingly, this is
to advise the Company that any materials and/or documents belonging to a former employer and which are not generally available to the public that Employee has brought or will bring to the Company or
has used or will use in Employee's employment are identified in Exhibit A appended to this Agreement, and as to each such item, Employee
represents that Employee has obtained prior to the effective date of this Agreement written authorization for their possession and use in Employee's employment with the Company. 


        6.     Employee
recognizes that the services to be performed by Employee hereunder are special, unique, and extraordinary and that, by reason of Employee's employment with the
Company, Employee may acquire Confidential Information (as hereinafter defined) concerning the operation of the Company, the use or disclosure of which would cause the Company substantial loss and
damage which could not be readily calculated and for which no remedy at law would be adequate. Accordingly, Employee agrees that Employee will not (directly or indirectly) at any time, whether during
or after Employee's employment with the Company: 



	(i)
	knowingly
use for personal benefit or for any other reason not authorized by the Company any Confidential Information that Employee may acquire or has acquired by reason
of Employee's employment with the Company, or;



	(ii)
	disclose
any such Confidential Information to any person or entity except (A) in the performance of Employee obligations to the Company hereunder, (B) as
required by a court of competent jurisdiction, (C) in connection with the enforcement of Employee rights under this Agreement, or (D) with the prior consent of the Board of Directors of
the Company. 




        As
used herein, "Confidential Information" includes information with respect to the facilities and methods of the Company, reagents, chemical compounds, cell lines or subcellular
constituents, organisms, or other biological materials, trade secrets, and other Intellectual Property, systems, patents and patent applications, procedures, manuals, confidential reports, financial
information, business plans, prospects, or opportunities, personnel information, or lists of customers and suppliers; provided, however, that Confidential Information shall not include any information
that is known or becomes generally known or available publicly other than as a result of disclosure by Employee which is not permitted as described in clause (ii) above, or the Company
discloses same to others without obtaining an agreement of confidentiality. 


        Employee
confirms that all Confidential Information is the exclusive property of the Company. All business records, papers, documents and electronic materials kept or made by Employee
relating to the business of the Company which comprise Confidential Information shall be and remain the property of the Company during the Employee's employment and at all times thereafter. Upon the
termination, for any reason, of Employee's employment with the Company, or upon the request of the Company at any time, Employee shall deliver to the Company, and shall retain no copies of any written
or electronic materials, records and documents made by Employee or coming into Employee's possession concerning the business or affairs of the Company and which comprise Confidential Information. 


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        7.     During
the term of Employee's employment with the Company and, in the event of any termination of the Employee's employment, for a period of eighteen (18) months
after the date of termination of the Employee's employment with the Company (the "Restricted Period"), the Employee shall not directly or indirectly, for Employee's own account or for the account of
others, as an employee, consultant or otherwise render services to any person or organization engaged in, or about to become engaged in, research on or the acquisition, development, production,
distribution, marketing, or providing of a product, process or service that competes or is reasonably expected to compete with a material product, process or service in existence or being developed by
the Company (a "Competing Organization"). 


        During
the Restricted Period, the Employee shall not, whether for Employee's own account or for the account of any other person (excluding the Company): 



	(i)
	solicit
or contact in an effort to do business with any person who was or is a customer of the Company during the term of this Agreement or after its termination, or any
affiliate of any such person, if such solicitation or contact is for the purpose of competition with the Company; or



	(ii)
	solicit
or induce any of the Company's employees to leave their employment with the Company or accept employment with anyone else, or hire any such employees or persons
who were employed by the Company during the preceding twelve (12) months. 




        The
Company agrees to permit Employee to accept employment with a Competing Organization, provided that Employee's duties with that Competing Organization during the eighteen
(18) month period following the termination of Employee's employment with the Company do not include duties relating to any product, process or service that competes or is reasonable expected
to compete with a material product, process or service in existence or being developed by the Company, and provided that Employee will have delivered to the Company a written statement, confirmed by
Employee's
prospective employer, describing Employee's duties and stating that such duties are consistent with Employee's obligations under this Agreement. 


        Employee
has carefully read and considered the provisions of this Section 7 (including the Restricted Period and scope of activity to be restrained) and concluded them to be fair,
appropriate and reasonably required for the protection of the legitimate business interests of the Company, its officers, directors, employees, creditors, and shareholders. Employee understands that
the restrictions contained in this Section 7 may limit Employee's ability to perform certain duties for a Competing Organization, but acknowledges that Employee will receive adequate and
affluent remuneration and other benefits from the Company hereunder to justify such restrictions. 


        The
Employee shall give prompt notice to the Company of the Employee's acceptance of employment or other fees for services relationship during the Restricted Period, which notice shall
include the name of, the business of, and the position that Employee shall hold with such other employer. 



        8.     In
the event that Employee's employment is transferred by the Company to a subsidiary, affiliated company, or acquiring company (as the case may be), Employee's
employment by such company will, for the purpose of this Agreement, be considered as continued employment with the Company, unless Employee executes an agreement, substantially similar in substance to
this Agreement, and until the effective date of said agreement in any such company for which Employee becomes employed. It is likewise agreed that no changes in Employee's position or title will
operate to terminate the provisions of this Agreement unless expressly agreed to in writing. 



        9.     Upon
termination of Employee's employment for any reason, unless such employment is transferred to a subsidiary, affiliated or acquiring company of the Company, Employee
agrees to leave with, or return to, the Company all records, drawings, notebooks, and other documents pertaining to 


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the
Company's Confidential Information, whether prepared by Employee or others, as well as any equipment, tools or other devices owned by the Company, that are then in Employee's possession, however
such items were obtained, and Employee agrees not to reproduce or otherwise retain any document or data relating thereto. 



        10.   Employee
obligations under this Agreement shall survive the termination of Employee's employment with the Company regardless of the manner of, and reason for, such
termination, and shall be binding upon Employee's heirs, executors, and administrators. 


        11.   Prior
to entering the employ of the Company, Employee has lawfully terminated employment with all previous employers. Employee acknowledges that this Agreement does not
constitute a contract of employment for a term and does not otherwise imply that the Company will continue his or her employment for any period of time. Employee further understands and agrees that no
license to any of the Company's trademarks, patents, copyrights or other proprietary rights is either granted or implied by Employee's access to and utilization of the Confidential Information or
Intellectual Property. 


        12.   As
a matter of record, Employee has identified in Exhibit B, appended to this Agreement, all Intellectual Property
relevant to the subject matter of Employee's employment with the Company, which has been made or conceived or first reduced to practice by Employee alone or jointly with others prior to Employee's
employment with the Company (collectively referred to as "Prior Intellectual Property") which Employee desires to exclude from Employee's obligations under this Agreement; and Employee represents that
such list is complete. If there is no such list set forth in Exhibit B, Employee represents that Employee has no such Intellectual Property at
the time of execution of this Agreement. If, in the course of Employee's employment with the Company, Employee incorporates into a Company product, process or machine Prior Intellectual Property owned
by Employee or in which Employee has an interest, the Company is hereby granted and will have a non-exclusive, royalty-free, irrevocable, perpetual, worldwide license to make,
have made, modify, use and sell the Prior Intellectual Property as part of or in connection with the product, process or machine. 


        13.   No
delay or omission by the Company in exercising any right under this Agreement will operate as a waiver of that or any other right. A waiver or consent given by the
Company on any one occasion is effective only in that instance and will not be construed as a bar to or waiver of any right on any other occasion. 


        14.   Employee
agrees that in addition to any other rights and remedies available to the Company for any breach or threatened breach by Employee of Employee's obligations
hereunder, the Company shall be entitled to enforcement of Employee's obligations hereunder by whatever means are at the Company's disposal, including court injunction. In the event of any such breach
or threatened breach by Employee, the Company shall be entitled to recover all of its reasonably incurred costs and attorney's fees in enforcing its rights hereunder. 



        15.   The
Company may assign this Agreement to any other corporation or entity which acquires (whether by purchase, merger, consolidation or otherwise) all or substantially
all of the business and/or assets of the Company. Employee shall have no rights of assignment. 


        16.   If
any provision of this Agreement shall be declared invalid, illegal, or unenforceable, then such provision shall be enforceable to the extent that a court deems it
reasonable to enforce such provision. If such provision shall be unreasonable to enforce to any extent, such provision shall be severed and all remaining provisions shall continue in full force and
effect. 


        17.   Employee
hereby acknowledges receipt of the Company's Confidentiality Policy. 


        18.   This
Agreement shall be effective as of the date first written above. 


        19.   This
Agreement shall be governed in all respects by the laws of the Commonwealth of Massachusetts. Each of the Company and Employee (a) hereby irrevocably submits
to the exclusive 


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jurisdiction
of the state courts of The Commonwealth of Massachusetts or the United States District Court located in The Commonwealth of Massachusetts for the purpose of any action between the Company
and Employee arising in whole or in part under or in connection with this Agreement, (b) hereby waives, to the extent not prohibited by applicable law, and agrees not to assert, by way of
motion, as a defense or otherwise, in any such action, any claim that it is not subject personally to the jurisdiction of the above-named courts, that its property is exempt or immune from attachment
or execution, that any such action brought in one of the above-named courts should be dismissed on grounds of forum non conveniens, should be
transferred or removed to any court other than one of the above-named courts, or should be stayed by reason of the pendency of some other proceeding in any other court other than one of the
above-named courts, or that this Agreement or the subject matter hereof may not be enforced in or by such court, and (c) hereby agrees not to commence any such action other than before one of
the above-named courts. Notwithstanding the previous sentence, the Company or Employee may commence any action in a court other than the above-named courts solely for the purpose of enforcing an order
or judgment issued by one of the above-named courts. 


[Remainder
of page intentionally left blank.] 


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        IN WITNESS WHEREOF, Employee has executed this Agreement under seal as of the date set forth above: 



	

BY:	

    
	
 	

 
	Name of Employee:	 	 
	
ACCEPTED AND AGREED TO:	
 	

 
	

Sirtris Pharmaceuticals, Inc.	
 	

 
	

BY:	

    
	
 	

 
	Name:	 	 	 
	Title:	 	 	 




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Exhibit 10.19