ViroPharma Bonus Plan



 Exhibit 10.22 
 ViroPharma Bonus Plan 
 The ViroPharma Incorporated Bonus Plan applies to each of our employees, including the
members of our management team. Each employee receives a target bonus, expressed as a percentage of his or her base salary for the year. The amount of a specific employee’s target bonus varies by the employee’s role in the Company and his
or her applicable pay band, as identified in the table below: 
  
  

											
	Exempt Positions	  		  			 		
					
	  	 	 Position
	  	Pay Band(s)	  	Target	 	 	Maximum	 
		 	 CEO
	  	18	  	50	%	 	62.5	%
		 	 Management Team
	  	17B	  	50	%	 	62.5	%
		 	 Management Team
	  	17A	  	40	%	 	50	%
		 	 Vice President
	  	16	  	30	%	 	37.5	%
		 	 Senior Director
	  	15B	  	30	%	 	37.5	%
		 	 Director
	  	15A	  	20	%	 	25	%
		 	 Associate Director
	  	14	  	20	%	 	25	%
		 	 Assistant Director
	  	13B	  	20	%	 	25	%
		 	 Manager
	  	13A	  	15	%	 	18.75	%
		 	 Senior Professional
	  	12	  	15	%	 	18.75	%
		 	 Senior Professional
	  	11	  	12	%	 	15	%
		 	 Mid-level Professional
	  	10	  	12	%	 	15	%
		 	 Professional
	  	9	  	12	%	 	15	%
		 	 Entry Level
	  	7-8	  	10	%	 	12.5	%
				
	 Non-Exempt Positions
	  		  			 		
					
		 	 Senior Non-Exempt
	  	6	  	10	%	 	12.5	%
		 	 Non-Exempt
	  	5	  	10	%	 	12.5	%
		 	 Non-Exempt
	  	2-4	  	8	%	 	10	%
		 	 Non-Exempt
	  	1	  	6	%	 	7.5	%

 For employees with less than one year of service, the bonus will be pro-rated based on the actual base pay
earnings during the bonus year. Overtime earnings are not eligible to be included in bonus calculations. 
 Awards pursuant to the plan are based upon two
factors: Company and Individual. The Company factor represents the degree to which we achieved our overall corporate goals in a given year. Each employee also is given an Individual factor by his or her supervisor to reflect the employee’s
performance against his or her individual goals for the year. Each factor can be assigned a value of up to 125% for maximum performance. Thus, depending on the performance of the Company and the individual employee, an employee may receive up to
125% of his or her target bonus. 







 Each of the Company and Individual factors is itself separately weighted for each employee. The weighting assigned to
each factor varies by employee depending on the role he or she plays with the Company and his or her applicable pay band. For example, for the members of the company’s management team, the Company factor is weighted significantly higher than
the Individual factor in order to ensure that the bonus system for the company’s management team is closely tied to the company’s performance. 
 The weighting of the factors is as follows: 
  

							
	 Exempt Positions
	  	Company Factor	 	 	Individual Factor	 
	 Pay Bands 17A, 17B, 18
	  	70	%	 	30	%
	 Pay Bands 15A, 15B, 16
	  	60	%	 	40	%
	 All others
	  	50	%	 	50	%

 To determine the actual bonus paid, an employee’s target payout percentage is multiplied by the sum of the
Company factor plus the Individual factor as each is weighted for such employee. The result of that calculation is then multiplied by the employee’s target bonus. 
 Whether or not a bonus is actually paid, however, is ultimately at the discretion of the Compensation Committee of the Board of Directors. Bonuses, if any, are paid during the first quarter of the year immediately
following the year being measured.