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                                                                 Exhibit 10.25.3

                                SECOND AMENDMENT

                                       TO

                           LEASE TERMINATION AGREEMENT

     This Second Amendment To Lease Termination Agreement ("Agreement") is dated
and effective April 2, 2003, and is entered into by and among WILLOW PARK
HOLDING COMPANY II, LLC, a Delaware limited liability company ("Willow Park"),
AMB PROPERTY, L.P., a Delaware limited partnership ("AMB", and together with
Willow Park, the "Landlords") and DELTAGEN, INC., a Delaware corporation
("Tenant").

     WHEREAS, Willow Park and Tenant entered into that certain Lease Termination
Agreement dated March 27, 2003, as amended by that certain First Amendment to
Lease Termination Agreement dated April 1, 2003 (collectively, the "Termination
Agreement") whereby Tenant was to pay Landlords a certain Termination Payment
upon Tenant obtaining Interim Financing;

     WHEREAS, Tenant paid Landlords the Termination Payment on March 31, 2003,
however, Tenant did not obtain the Interim Financing until April 2, 2003; and

     WHEREAS, the parties desire to amend the Termination Agreement to provide
that the Termination Payment was due and was paid on March 27, 2003 and that
Tenant was not and is not in breach of the Termination Agreement for not
obtaining Interim Financing until April 2, 2003.

     NOW, THEREFORE, for and in consideration of the mutual covenants and
promises herein contained, and for other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, the parties hereto
agree as follows:

     1. Capitalized Terms. All capitalized terms herein shall have the same
meaning as the Termination Agreement.

     2. Modification of Interim Financing Definition. "Interim Financing" as
defined in Section 1(b) of the Termination Agreement shall be replaced with the
following: "Interim Financing shall mean Tenant's consummation of an interim
equity or debt financing in an amount not less than $4,000,000 which financing
must occur on or before April 2, 2003."

     3. Confirmation of Interim Financing. Tenant hereby represents and warrants
that it has obtained such Interim Financing effective as of April 2, 2003.

     4. Miscellaneous. Warranties, representations, agreements, and obligations
contained in this Agreement shall survive the execution and delivery of this
Agreement and shall survive any and all performances in accordance with this
Agreement. This Agreement may be executed in any number of counterparts which
together shall constitute the Agreement. Faxed signatures hereon shall be deemed
originals for all purposes. If any party obtains a judgment against any other
party by reason of breach of this Agreement, reasonable attorneys' fees as fixed

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by the court shall be included in such judgment. This Agreement and the terms
and provisions hereof shall inure to the benefit of and be binding upon the
heirs, successors and assigns of the parties. This Agreement shall be construed
and enforced in accordance with the laws of the State of California.

     IN WITNESS WHEREOF, the parties have executed this Agreement as of the date
first written above.

                                WILLOW PARK:

                                WILLOW PARK HOLDING COMPANY II, LLC
                                a Delaware limited liability company

                                By:  AMB Property, L.P., a Delaware limited
                                     partnership, its Manager

                                     By:   AMB Property Corporation, a Maryland
                                           corporation, its General Partner

                                           By:__________________________________
                                                 John Rossi

                                           Its: Senior Vice President

                                           Date:________________________________


                                     AMB:

                                     AMB PROPERTY, L.P.,
                                     a Delaware limited partnership

                                     By:  AMB PROPERTY CORPORATION
                                          a Maryland corporation, its general
                                          partner

                                          By:___________________________________
                                                 John Rossi

                                          Its:  Senior Vice President

                                          Date:_________________________________

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                                          TENANT:

                                          DELTAGEN, INC.,
                                          a Delaware corporation

                                          By:___________________________________
                                          Its:__________________________________


                                          By:___________________________________
                                          Its:__________________________________


                                          Date:_________________________________

If Tenant is a CORPORATION, the authorized officers must sign on behalf of the
corporation and indicate the capacity in which they are signing. The Lease must
be executed by the president or vice-president and the secretary or assistant
secretary, unless the bylaws or a resolution of the board of directors shall
otherwise provide, in which event, the bylaws or a certified copy of the
resolution, as the case may be, must be attached to this Lease.

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