Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

E. I. DU PONT DE NEMOURS AND COMPANY (S300/419)

1007 MARKET STREET

WILMINGTON, DE 198980001

Environmental Fate Data Requirements (Conventional 

Chemical)

835.1230

835.1240

835.2120

835.4100

835.4200

835.4300

835.6100

Sediment and soil absorption/desorption for parent 

and degradates

Soil column leaching

Hydrolysis of parent and degradates as a function of 

pH at 25 C

Aerobic soil metabolism

Anaerobic soil metabolism

Aerobic aquatic metabolism

Terrestrial field dissipation

N/A - Indoxacarb

Chemical # and Name: 067710

Indoxacarb

GENERIC

ID # GDCI-067710-1382

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

GUIDELINE

GUIDELINE

GUIDELINE

GUIDELINE

GUIDELINE

GUIDELINE

GUIDELINE

12

12

12

24

24

24

12

Page 1 of 

(2)

(2)

(2)

(2)

(7)

(2)

(8)

N

N

N

N

N

N

N

3
OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

E. I. DU PONT DE NEMOURS AND COMPANY (S300/419)

1007 MARKET STREET

WILMINGTON, DE 198980001

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

850.4100

850.4150

850.1075

850.2100

850.6100

SS-1228

Seedling Emergence and Seedling Growth

Vegetative Vigor

Fish acute toxicity test, freshwater and marine

Avian acute oral toxicity test

Environmental Chemistry Methods and Associated 

Independent Laboratory Validation

Larval honey bee acute oral toxicity

N/A - Indoxacarb

Chemical # and Name: 067710

Indoxacarb

GENERIC

ID # GDCI-067710-1382

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

TEP

TEP

GUIDELINE

TGAI

GUIDELINE

TGAI

12

12

12

12

12

Page 2 of 

(3)

(3)

(5)

(4)

(6)

(4)

N

N

N

Y

N

Y

3
Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

E. I. DU PONT DE NEMOURS AND COMPANY (S300/419)

1007 MARKET STREET

WILMINGTON, DE 198980001

SS-1231 Whole sediment chronic invertebrates freshwater and

marine

N/A - Indoxacarb

Chemical # and Name: 067710

Indoxacarb

GENERIC

ID # GDCI-067710-1382

N,K,Y,II,L,Q,C,Z,R,B,O,A

,S,V,HH,M,U,EE

TGAI 24

Page 3 of 

(1) Y

3
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

N/A - Indoxacarb

GDCI-067710-1382

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Case # and Name:

DCI Number:

Page: 1 of

Use Categories Key:

A - Terrestrial food crop

B - Terrestrial feed crop

C - Terrestrial nonfood crop

K - Residential

L - Indoor food use

M - Indoor nonfood use

N - Indoor medical use

O - Residential Indoor use

Q - Residential outdoor use

R - Agricultural premises and equipment

S - Food handling/storage establishments premises

and equipment

U - Residential and public access premises

V - Medical premises and equipment

Y - Industrial processes and water systems - 

once through 

Z - Industrial processes and water systems - not 

once through

EE - Indoor use

HH - Occupational Use Conventional Chemical

II - Residential Use Conventional Chemical

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

N/A - Indoxacarb

GDCI-067710-1382

1

2

3

4

5

6

7

8

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

To be conducted with Chironomus dilutus, Hyalella azteca, and Leptocheirus plumulosus. All sediment testing should include quantification of parent indoxacarb DPX-MP062, IN-JT333 and INMP819 in both pore water and sediment and report results (i.e.., endpoints) in terms of parent indoxacarb, IN-JT333 and IN-MP819.

A tiered approach using toxicity data from sub-chronic (10-day) sediment toxicity tests with parent indoxacarb and the three species may be used to determine which species should undergo 

chronic toxicity testing.

Study to be conducted on TGAI and degradates IN-JT333 and IN-MP819.

Study to be conducted on TEP with DPX-MP062 and TEP enriched in DPX-KN128.

Study is to be conducted on DPX-MP062.

Study is to be conducted on DPX-MP062 with estuarine/marine fish and degradate IN-MP819 with freshwater fish and coldwater species.

EPA requires environmental chemistry methods and independent lab validations for soil, water, and sediment with TGAI and degradates IN-JT333 and IN-MP819.

EPA requires anaerobic soil metabolism data for four soils. EPA requires a protocol be submitted for review and comment within 60 days of receipt of this DCI. Study to be conducted on DPXMP062.

EPA requires ONLY the storage stability in soil portion of GDLN 835.6100, not the full terrestrial field dissipation study. Study is to be conducted on DPX-MP062.

Case # and Name:

DCI Number:

Page: 2 of 2

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.