Initial to indicate certification as to information on this page (full text of certification is on page one) 13. Phone Number 10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. 12. Name of Company 11. Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________ E. I. DU PONT DE NEMOURS AND COMPANY (S300/419) 1007 MARKET STREET WILMINGTON, DE 198980001

Environmental Fate Data Requirements (Conventional Chemical) 835.1230 835.1240 835.2120 835.4100 835.4200 835.4300 835.6100 Sediment and soil absorption/desorption for parent

and degradates Soil column leaching Hydrolysis of parent and degradates as a function of pH at 25 C Aerobic soil metabolism Anaerobic soil metabolism Aerobic aquatic metabolism Terrestrial field dissipation N/A - Indoxacarb Chemical # and Name: 067710 Indoxacarb GENERIC ID # GDCI-067710-1382

N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE GUIDELINE GUIDELINE GUIDELINE GUIDELINE GUIDELINE GUIDELINE GUIDELINE 12 12 12 24 24 24 12 1 of Page

(2) (2) (2) (2) (7) (2) (8) N N N N N N N 3OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number E. I. DU PONT DE NEMOURS AND COMPANY (S300/419) 1007 MARKET STREET WILMINGTON, DE 198980001

Nontarget Plant Protection Data Requirements (Conventional Chemical)

Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical) 850.4100 850.4150

850.1075 850.2100

850.6100 SS-1228 Seedling Emergence and Seedling Growth

Vegetative Vigor
Fish acute toxicity test, freshwater and marine Avian acute oral toxicity test
Environmental Chemistry Methods and Associated Independent Laboratory Validation Larval honey bee acute oral toxicity N/A - Indoxacarb Chemical # and Name: 067710 Indoxacarb GENERIC ID # GDCI-067710-1382

N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE
N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE TEP TEP

GUIDELINE TGAI

GUIDELINE TGAI 12 12

12

12 12 2of Page

(3) (3)
(5) (4)
(6) (4) N N

N Y

N Y 3Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number E. I. DU PONT DE NEMOURS AND COMPANY (S300/419) 1007 MARKET STREET WILMINGTON, DE 198980001

SS-1231 Whole sediment chronic invertebrates freshwater and

marine N/A - Indoxacarb Chemical # and Name: 067710 Indoxacarb GENERIC ID # GDCI-067710-1382

N,K,Y,II,L,Q,C,Z,R,B,O,A ,S,V,HH,M,U,EE TGAI 24 3of Page

(1) Y 3

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS N/A - Indoxacarb GDCI-067710-1382 Key:Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient Case # and Name: DCI Number: 1 Page: of

Use Categories Key: A - Terrestrial food crop B - Terrestrial feed crop C - Terrestrial nonfood crop K - Residential L - Indoor food use M - Indoor nonfood use N - Indoor medical use O - Residential Indoor use Q - Residential outdoor use R - Agricultural premises and equipment S - Food handling/storage establishments premises and equipment U - Residential and public access premises V - Medical premises and equipment Y - Industrial processes and water systems - once through Z - Industrial processes and water systems - not once through EE - Indoor use HH - Occupational Use Conventional Chemical II - Residential Use Conventional Chemical 2

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS N/A - Indoxacarb GDCI-067710-1382

1

2 3 4 5 6 7 8 Key:Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

To be conducted with Chironomus dilutus, Hyalella azteca, and Leptocheirus plumulosus. All sediment testing should include quantification of parent indoxacarb DPX-MP062, IN-JT333 and INMP819 in both pore water and sediment and report results (i.e.., endpoints) in terms of parent indoxacarb, IN-JT333 and IN-MP819. A tiered approach using toxicity data from sub-chronic (10-day) sediment toxicity tests with parent indoxacarb and the three species may be used to determine which species should undergo chronic toxicity testing. Study to be conducted on TGAI and degradates IN-JT333 and IN-MP819. Study to be conducted on TEP with DPX-MP062 and TEP enriched in DPX-KN128. Study is to be conducted on DPX-MP062. Study is to be conducted on DPX-MP062 with estuarine/marine fish and degradate IN-MP819 with freshwater fish and coldwater species. EPA requires environmental chemistry methods and independent lab validations for soil, water, and sediment with TGAI and degradates IN-JT333 and IN-MP819.EPA requires anaerobic soil metabolism data for four soils. EPA requires a protocol be submitted for review and comment within 60 days of receipt of this DCI. Study to be conducted on DPXMP062. EPA requires ONLY the storage stability in soil portion of GDLN 835.6100, not the full terrestrial field dissipation study. Study is to be conducted on DPX-MP062. Case # and Name: DCI Number: 2 Page: of 2

Footnotes:The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.