|Exhibit 99.1
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|CERTIFICATION PURSUANT TO
SECTION 302(a) OF THE SARBANES-OXLEY ACT OF 2002
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|I, Geoffrey P. Kempler, certify that:
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|1. I have reviewed this annual report on Form
20-F of Prana Biotechnology Limited;
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|2. Based on my knowledge, this annual report
does not contain any untrue statement of a material fact or omit to state a  material
fact necessary to make the statements made, in light of the circumstances under which
such statements were made,  not misleading with respect to the period covered by this
annual report;
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|3. Based on my knowledge, the financial
statements, and other financial information included in this annual report,  fairly
present in all material respects the financial condition, results of operations and cash
flows of the registrant  as of, and for, the periods presented in this annual report;
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|4. The registrants other certifying officers
and I are responsible for establishing and maintaining disclosure controls  and
procedures (as defined in Exchange Act Rules 13a-14 and 15d-14) for the registrant and we
have:
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|a) designed such disclosure controls and
procedures to ensure that material information relating to the registrant,  including its
consolidated subsidiaries, is made known to us by others within those entities,
particularly during the  period in which this annual report is being prepared;
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|b) evaluated the effectiveness of the
registrants disclosure controls and procedures as of a date within 90 days prior  to the
filing date of this annual report (the Evaluation Date); and
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|c) presented in this annual report our
conclusions about the effectiveness of the disclosure controls and procedures  based on
our evaluation as of the Evaluation Date;
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|5. The registrants other certifying officers
and I have disclosed, based on our most recent evaluation, to the  registrants auditors
and the audit committee of registrants board of directors (or persons performing the
equivalent  function):
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|a) all significant deficiencies in the design or
operation of internal controls which could adversely affect the  registrants ability to
record, process, summarize and report financial data and have identified for the
registrants  auditors any material weaknesses in internal controls; and
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|b) any fraud, whether or not material, that
involves management or other employees who have a significant role in the  registrants
internal controls; and
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|6. The registrants other certifying officers
and I have indicated in this annual report whether or not there were  significant changes
in internal controls or in other factors that could significantly affect internal
controls subsequent  to the date of our most recent evaluation, including any corrective
actions with regard to significant deficiencies and  material weaknesses.
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|Date:  January 9, 2003
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|/s/ Geoffrey P. Kempler *
      Geoffrey P. Kempler
      Chief Executive Officer
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|* |  | The
originally executed copy of this Certification will be maintained at the  Companys
offices and will be made available for inspection upon request.
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