Revision date: 30 June 2011

Version: 2.0

Page 1 of 11

SAFETY DATA SHEET

SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE 

COMPANY/UNDERTAKING

Emergency telephone

number (Chemtrec):

1-(800) 424-9300 (US and 

Canada)

1-(703) 527-3887 (Collect 

calls accepted)

Product identifier

Synonyms

Trade names

Chemical family

Relevant identified uses of 

the substance or mixture 

and uses advised against

To be handled by trained personnel for research and development purposes only.

Note The pharmacologic and toxicologic properties of this have not been fully 

characterized; this SDS will be revisited as more data become available. 

Issue Date 30 June 2011 

SECTION 2 - HAZARDS IDENTIFICATION

Classification of the 

substance or mixture

Regulation (EC) 

1272/2008 [GHS]

Skin Sensitizer - Category 1. not yet fully tested 

Directive 67/548/EEC or 

1999/45/EC

Xi - R43. not yet fully tested 

Label elements
Revision date: 30 June 2011

Version: 2.0

Page 2 of 11

SECTION 2 - HAZARDS IDENTIFICATION ...continued

CLP/GHS hazard 

pictogram

CLP/GHS signal word Warning 

CLP/GHS hazard 

statements

H317 - May cause allergic skin reaction. 

CLP/GHS precautionary 

statements

P261 - Avoid breathing mist/vapor/spray. P272 - Contaminated work clothing 

should not be allowed out of the workplace. P280 - Wear protective gloves/eye 

protection/face protection. P302 + P352 - If on skin: Wash with plenty of soap and 

water. P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention. 

P363 - Wash contaminated clothing before reuse. P501 - Dispose of 

contents/container to location in accordance with 

local/regional/national/international regulations. 

Other hazards No information identified. 

US Signal word Warning 

US Hazard overview May cause allergic skin reaction. not yet fully tested. 

Note This is classified as hazardous according to Directive 67/548/EEC, 

Regulation EC No 1272/2008 (EU-CLP), and applicable US regulations. The 

pharmacological, toxicological, and ecological properties have not been fully 

characterized. See Section 16 for full text of EU and GHS classifications. The 

GHS classifications are based on Regulation (EC) 1272/2008. 

SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS

Ingredient CAS # EINECS/ELIN

CS#

Amount EU 

Classification

GHS 

Classification

Not classified Not classified

Xi - Irritant: 

R43

SS1: H317
Revision date: 30 June 2011

Version: 2.0

Page 3 of 11

SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS ...continued

Note The ingredient(s) listed above are considered hazardous. The pharmacological and 

toxicological characteristics of this have not been fully characterized. See 

Section 16 for full text of EU and GHS classifications. The EU classification is 

based on Directive 67/548/EEC and the GHS classification is based on Regulation 

(EC) 1272/2008. 

SECTION 4 - FIRST AID MEASURES

Description of first aid 

measures

Immediate Medical 

Attention Needed

Yes 

Eye Contact If easy to do, remove contact lenses, if worn. Immediately flush eyes with copious 

quantities of water for at least 15 minutes. If irritation occurs or persists, notify 

medical personnel and supervisor. 

Skin Contact Wash exposed area with soap and water and remove contaminated clothing/shoes. 

If irritation occurs or persists, notify medical personnel and supervisor. 

Inhalation Immediately move exposed subject to fresh air. If not breathing, give artificial 

respiration. If breathing is labored, administer oxygen. Immediately notify medical 

personnel and supervisor. 

Ingestion If swallowed, call a physician immediately. Do not induce vomiting unless 

directed by medical personnel. Do not give anything to drink unless directed by 

medical personnel. Never give anything by mouth to an unconscious person. 

Notify medical personnel and supervisor. 

Protection of first aid 

responders

See Section 8 for Exposure Controls/Personal Protection recommendations. 

Most important symptoms 

and effects, both acute and 

delayed

See Sections 2 and 11 

Indication of immediate 

medical attention and 

special treatment needed, if 

necessary

Treat symptomatically and supportively. If accidental exposure occurs to an 

individual who is also taking one or more concomitant medications, consult the 

respective package or prescribing information for potential drug interactions. 

SECTION 5 - FIREFIGHTING MEASURES

Extinguishing media Use water spray (fog), foam, dry powder, or carbon dioxide, as appropriate for 

surrounding fire and materials. 
Revision date: 30 June 2011

Version: 2.0

Page 4 of 11

SECTION 5 - FIREFIGHTING MEASURES ...continued

Specific hazards arising 

from the substance or 

mixture

No information identified. May emit toxic fumes of carbon monoxide and carbon 

dioxide. 

Flammability/Explosivity No explosivity or flammability data identified. High airborne concentrations of 

finely divided organic particles can potentially explode if ignited. 

Advice for firefighters Wear full protective clothing and a self-contained breathing apparatus with a full 

facepiece operated in the pressure demand or other positive pressure mode. 

Decontaminate all equipment after use. 

SECTION 6 - ACCIDENTAL RELEASE MEASURES

Personal precautions, 

protective equipment and 

emergency procedures

If product is released or spilled, take proper precautions to minimize exposure by 

using appropriate personal protective equipment (see Section 8). Area should be 

adequately ventilated. 

Environmental precautions Do not empty into drains. Avoid release to the environment. 

Methods and material for 

containment and cleaning 

up

For small spills (such as in a laboratory), soak up material with absorbent, e.g., 

damp paper towel, and wash spill area thoroughly with soap and water. For large 

spills in manufacturing, use an industrial vacuum cleaner equipped with a high 

efficiency particulate (HEPA) filter if available. Alternatively if in solid or dried 

form, do not raise dust. Surround spill or powder with absorbents and place a 

damp cloth or towel over the area to minimize powder from entering the air. Add 

excess liquid to allow for the material to enter solution. Capture remaining liquid 

onto spill absorbents. Place spill materials into a leak-proof container suitable for 

disposal. Decontaminate area a second time. Dispose of material in a manner that 

is compliant with federal, state and local laws. 

Reference to other sections See Sections 8 and 13 for more information. 

SECTION 7 - HANDLING AND STORAGE

Precautions for safe 

handling

Avoid contact with eyes, skin and other mucous membranes. Wash thoroughly 

after handling. Use personal protective equipment. Avoid breathing vapor. Do not 

eat, drink or smoke while handling this product. Avoid prolonged or repeated 

exposure. Provide sufficient air exchange and/or exhaust in workrooms. Take 

precautionary measures against static discharges. Use normal preventative fire 

protection measures. 

Conditions for safe storage 

including any 

incompatibilities

Keep container tightly closed. Keep in a cool and well ventilated area away from 

any ignition source. To maintain product quality, do not store in heat or direct 

sunlight. 
Revision date: 30 June 2011

Version: 2.0

Page 5 of 11

SECTION 7 - HANDLING AND STORAGE ...continued

Specific end use(s) No information identified. 

SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION

Control 

Parameters/Occupational 

Exposure Limit Values

Compound Issuer Type OEL

-- -- --

-- -- --

Exposure/Engineering 

controls

Selection and use of containment devices and personal protective equipment 

should be based on a risk assessment of exposure potential. Use local exhaust and/ 

or enclosure at mist/aerosol/spray-generating points. High-energy operations such 

as spraying should be done within an approved emission control or containment 

system. 

Respiratory protection Choice of respiratory protection should be appropriate to the task and the level of 

existing engineering controls. An approved and properly fitted air-purifying 

respirator with HEPA filters should provide ancillary protection based on the 

known or foreseeable limitations of existing engineering controls. Use a powered 

air-purifying respirator equipped with HEPA filters or combination filters or a 

positive-pressure air-supplied respirator if there is any potential for an 

uncontrolled release, when exposure levels are not known, or in any other 

circumstances where a lower level of respiratory protection may not provide 

adequate protection. 

Hand protection Wear nitrile or other impervious gloves if skin contact is possible. Double gloves 

should be considered. When the material is dissolved or suspended in an organic 

solvent, wear gloves that provide protection against the solvent. 

Skin protection Wear appropriate gloves, lab coat, or other protective overgarment if skin contact 

is likely. Base the choice of skin protection on the job activity, potential for skin 

contact and solvents and reagents in use. 

Eye/face protection Wear safety glasses with side shields, chemical splash goggles, or full face shield, 

if necessary. Base the choice of protection on the job activity and potential for 

contact with eyes or face. An emergency eye wash station should be available. 

Environmental Exposure 

Controls

Avoid release to the environment and operate within closed systems wherever 

practicable. Air and liquid emissions should be directed to appropriate pollution 

control devices. In case of spill, do not release to drains. Implement appropriate 

and effective emergency response procedures to prevent release or spread of 

contamination and to prevent inadvertent contact by personnel. 
Revision date: 30 June 2011

Version: 2.0

Page 6 of 11

SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION ...continued

Other protective 

measures

Wash hands in the event of contact with this substance, especially before eating, 

drinking or smoking. Protective equipment is not to be worn outside the work area 

(e.g., in common areas or out-of-doors). Decontaminate all protective equipment 

following use. 

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES

Information on basic 

physical and chemical 

properties

Appearance

Color

Odor

Odor threshold

pH

Melting point/freezing 

point

Initial boiling point and 

boiling range

Flash point

Evaporation rate

Flammability (solid, gas)

Upper/lower 

flammability or explosive

limits

Vapor pressure

Vapor density

Relative density

Water solubility

Solvent solubility

Partition coefficient 

(n-octanol/water)

Auto-ignition 

temperature
Revision date: 30 June 2011

Version: 2.0

Page 7 of 11

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ...continued

Decomposition 

temperature

Viscosity

Explosive properties

Oxidizing properties

Other information

Molecular weight

Molecular formula

SECTION 10 - STABILITY AND REACTIVITY

Reactivity No information identified. 

Chemical stability No information identified. 

Possibility of hazardous 

reactions

Not expected to occur. 

Conditions to avoid No information identified. 

Incompatible materials No information identified. 

Hazardous decomposition 

products

No information identified. 

SECTION 11 - TOXICOLOGICAL INFORMATION

Information on toxicological 

effects

Route of entry May be absorbed by inhalation, skin contact and ingestion. 

Acute toxicity

Compound Type Route Species Dose

-- -- -- --

LC50 Inhalation Rat >2.19 mg/L

LD50 Oral Rat > 5000 mg/kg

LD50 Dermal Rabbit > 5000 mg/kg
Revision date: 30 June 2011

Version: 2.0

Page 8 of 11

SECTION 11 - TOXICOLOGICAL INFORMATION ...continued

Irritation/Corrosion This has not been tested. is a dermal and eye irritant in rabbits. 

Sensitization This has not been tested. Skin sensitization was observed for in 

a local lymph node assay (LLNA) in mice. 

STOT-single exposure No studies identified. 

STOT-repeated 

exposure/Repeat-dose 

toxicity

No studies identified. 

Reproductive toxicity No studies identified. 

Developmental toxicity No studies identified. 

Genotoxicity was negative in the Ames bacterial cell mutagenicity assay. 

Carcinogenicity No studies identified. This substance is not listed by NTP, IARC, ACGIH or 

OSHA as a carcinogen. 

Aspiration hazard No data available. 

Human health data See "Section 2 - Other Hazards" 

Additional information not fully tested. 

SECTION 12 - ECOLOGICAL INFORMATION

Toxicity

Compound Type Species Concentration

-- -- --

-- -- --

Additional toxicity 

information

No data available. 

Persistence and 

Degradability

No data available. 

Bioaccumulative potential No data available. 

Mobility in soil No data available. 

Results of PBT and vPvB 

assessment

No data available. 
Revision date: 30 June 2011

Version: 2.0

Page 9 of 11

SECTION 12 - ECOLOGICAL INFORMATION ...continued

Other adverse effects No data available. 

Note The environmental characteristics of this have not been fully investigated. 

Releases to the environment should be avoided. 

SECTION 13 - DISPOSAL CONSIDERATIONS

Waste treatment methods Used product should be disposed of according to local, state, and federal 

regulations. Do not send down the drain or flush down the toilet. All wastes 

containing the material should be properly labeled. Dispose of wastes in 

accordance to prescribed federal, state, and local guidelines, e.g., appropriately 

permitted chemical waste incinerator. Rinse waters resulting from spill cleanups 

should be discharged in an environmentally safe manner, e.g., appropriately 

permitted municipal or on-site wastewater treatment facility. 

SECTION 14 - TRANSPORT INFORMATION

Transport Based on the available data, this is not regulated as a hazardous material/ 

dangerous good under EU ADR/RID, US DOT, Canada TDG, IATA, or IMDG. 

UN number None assigned. 

UN proper shipping name None assigned. 

Transport hazard classes 

and packing group

None assigned. 

Environmental hazards Based on the available data, this product/mixture is not regulated as an 

environmental hazard or a marine pollutant. 

Special precautions for 

users

not fully tested - avoid exposure. 

Transport in bulk according 

to Annex II of 

MARPOL73/78 and the IBC 

Code

Not applicable. 

SECTION 15 - REGULATORY INFORMATION

Safety, health and 

environmental 

regulations/legislation 

specific for the substance or 

mixture

This SDS complies with the requirements under US, EU and GHS (EU CLP -

Regulation EC No 1272/2008) guidelines. 
Revision date: 30 June 2011

Version: 2.0

Page 10 of 11

SECTION 15 - REGULATORY INFORMATION ...continued

Chemical safety assessment Not conducted. 

OSHA Hazardous Yes. May cause allergic skin reaction. not fully tested. 

WHMIS classification Not classified. This product has been classified in accordance with the hazard 

criteria of the Controlled Products Regulations and the SDS contains all of the 

information required by those regulations. 

TSCA status This is not listed on the TSCA inventory. 

SARA section 313 Not listed. 

California proposition 65 Not listed. 

SECTION 16 - OTHER INFORMATION

Full text of R phrases and 

EU Classifications

R43 - May cause sensitization by skin contact. not yet fully tested. 

Full text of H phrases, P 

phrases and GHS 

classification

SS1 - Skin sensitizer Category 1. H317 - May cause an allergic skin reaction. 

not yet fully tested. 

Sources of data Information from published literature and internal company data. 

Abbreviations ACGIH - American Conference of Governmental Industrial Hygienists ADR/RID 

- European Agreement Concerning the International Carriage of Dangerous Goods 

by Road/Rail AIHA - American Industrial Hygiene Association CAS# - Chemical 

Abstract Services Number DNEL - Derived No Effect Level DOT - Department of 

Transportation EINECS - European Inventory of New and Existing Chemical 

Substances ELINCS - European List of Notified Chemical Substances EU -

European Union GHS - Globally Harmonized System of Classification and 

Labelling of Chemicals IARC - International Agency for Research on Cancer 

IDLH - Immediately Dangerous to Life or Health IATA - International Air 

Transport Association IMDG - International Maritime Dangerous Goods LOEL -

Lowest Observed Effect Level LOAEL - Lowest Observed Adverse Effect Level 

NIOSH - The National Institute for Occupational Safety and Health NOEL - No 

Observed Effect Level NOAEL - No Observed Adverse Effect Level NTP -

National Toxicology Program OEL - Occupational Exposure Limit OSHA -

Occupational Safety and Health Administration PBT - Persistent, Bioaccumulative 

and Toxic PNEC - Predicted No Effect Concentration SARA - Superfund 

Amendments and Reauthorization Act STEL - Short Term Exposure Limit
Revision date: 30 June 2011

Version: 2.0

Page 11 of 11

SECTION 16 - OTHER INFORMATION ...continued

Abbreviations ...continued TDG - Transport Dangerous Goods TSCA - Toxic Substances Control Act TWA -

Time Weighted Average WHMIS - Workplace Hazardous Materials Information 

System 

Revisions This is the first version of this SDS. 

Disclaimer The above information is based on data available to us and is believed to be 

correct. Since the information may be applied under conditions beyond our control 

and with which we may be unfamiliar, we do not assume any responsibility for the 

results of its use and all persons receiving it must make their own determination of 

the effects, properties and protections which pertain to their particular conditions. 

No representation, warranty, or guarantee, express or implied (including a 

warranty of fitness or merchantability for a particular purpose), is made with 

respect to the materials, the accuracy of this information, the results to be obtained 

from the use thereof, or the hazards connected with the use of the material. 

Caution should be used in the handling and use of the material because it is a 

pharmaceutical product. The above information is offered in good faith and with 

the belief that it is accurate. As of the date of issuance, we are providing all 

information relevant to the foreseeable handling of the material. However, in the 

event of an adverse incident associated with this product, this Safety Data Sheet is 

not, and is not intended to be, a substitute for consultation with appropriately 

trained personnel.