[Federal Register Volume 75, Number 39 (Monday, March 1, 2010)]
[Notices]
[Pages 9205-9206]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2010-4138]


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ENVIRONMENTAL PROTECTION AGENCY

[FRL-9120-3]


Science Advisory Board Staff Office Notification of a Public 
Meeting of a Workgroup of the Chartered Science Advisory Board

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice.

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SUMMARY: The EPA Science Advisory Board (SAB) Staff Office announces a 
public meeting of a workgroup of the chartered Science Advisory Board 
to conduct an expedited and focused review of EPA's draft 
``Toxicological Review of Inorganic Arsenic: In Support of the Summary 
Information on the Integrated Risk Information System (IRIS)'' (EPA/
635/R-10/001). The SAB workgroup will assess the adequacy of EPA's 
implementation of the SAB previous recommendations regarding the cancer 
risk assessment of inorganic arsenic.

DATES: The meeting will be held on April 6, 2010 from 1 p.m. to 5:30 
p.m. (Eastern Time) and April 7, 2010 from 8:30 a.m. to 2 p.m. (Eastern 
Time).

ADDRESSES: The meeting will be held at the St. Regis Hotel, 923 16th 
and K Streets, NW., Washington, DC 20006.

FOR FURTHER INFORMATION CONTACT: Any member of the public wishing to 
obtain general information concerning this public meeting should 
contact Dr. Sue Shallal, Designated Federal Officer (DFO), EPA Science 
Advisory Board (1400F), 1200 Pennsylvania Avenue, NW., Washington, DC 
20460; via telephone/voice mail: (202) 343-9977; fax: (202) 233-0643; 
or e-mail at <a href="/cdn-cgi/l/email-protection#7e2d161f12121f12500d0b161f170c3e1b0e1f50191108"><span class="__cf_email__" data-cfemail="acffc4cdc0c0cdc082dfd9c4cdc5deecc9dccd82cbc3da">[email protected]</span></a>. General information concerning the 
EPA Science Advisory Board can be found on the SAB Web site at http://www.epa.gov/sab.

SUPPLEMENTARY INFORMATION: The SAB was established by 42 U.S.C. 4365 to 
provide independent scientific and technical advice to the 
Administrator on the technical basis for Agency positions and 
regulations. The SAB is a Federal advisory committee chartered under 
the Federal Advisory Committee Act (FACA), as amended, 5 U.S.C., App 2. 
The SAB will comply with the provisions of FACA and all appropriate SAB 
Staff Office procedural policies. Pursuant to the Federal Advisory 
Committee Act, Public Law 92-463, notice is hereby given that a 
workgroup of the chartered SAB will hold a public meeting to lead the 
review of the implementation of SAB's previous recommendations for the 
revision of EPA's cancer risk assessment of inorganic arsenic.
    Background: The EPA is currently in the process of updating the 
1988 IRIS cancer assessment for inorganic arsenic (iAs). The EPA 
evaluated and implemented the National Research Council (2001) 
recommendations and in 2005 requested that the SAB review the Agency's 
draft cancer assessment for iAs. The SAB review report was finalized in 
2007 and is available at the following URL: http://yosemite.epa.gov/
sab/sabproduct.nsf/02ad90b136fc21ef85256eba00436459/
EADABBF40DED2A0885257308006741EF/$File/sab-07-008.pdf.
    EPA's Office of Research Development has completed a 2010 draft 
``Toxicological Review of Inorganic Arsenic: In Support of the Summary 
Information on the Integrated Risk Information System (IRIS)'' (EPA/
635/R-10/001). This draft assessment includes an evaluation and 
characterization of

[[Page 9206]]

the potential cancer hazard of iAs and a quantitative dose-response 
cancer assessment for iAs. The draft assessment also provides a 
disposition of SAB's previous review comments and recommendations.
    In response to the Administrator's request, ORD is requesting that 
the SAB evaluate and comment on EPA's interpretation and implementation 
of the key SAB (2007) recommendations in the revised draft assessment. 
ORD is requesting an expedited and focused review of the draft 
assessment in three areas: Evaluation of epidemiological literature; 
dose-response modeling approaches; and the sensitivity analysis of the 
exposure assumptions used in the risk assessment. In response to this 
request, the SAB is convening a workgroup of the chartered SAB to lead 
this expedited and focused review and to assess the responsiveness of 
EPA's implementation of the previous SAB recommendations. The SAB 
workgroup's draft report will be reviewed and approved by the full 
Board in a subsequent public meeting to be announced in a separate 
Federal Register notice. Information about this SAB advisory activity 
can be found on the SAB Web site at http://yosemite.epa.gov/sab/sabproduct.nsf/fedrgstr_activites/Rev%20Tox%20Review%20Inorg%20Arsenic?OpenDocument.
    Availability of Meeting Materials: The agendas and other materials 
in support of the meeting will be placed on the SAB Web site at http://www.epa.gov/sab in advance. For technical questions and information 
concerning EPA's draft document, please contact Dr. Reeder Sams at 
(919) 541-0661, or <a href="/cdn-cgi/l/email-protection#a2d1c3cfd18cd0c7c7c6c7d0e2c7d2c38cc5cdd4"><span class="__cf_email__" data-cfemail="3043515d431e425555545542705540511e575f46">[email protected]</span></a>.
    Procedures for Providing Public Input: Interested members of the 
public may submit relevant written or oral information for the SAB to 
consider on the topics included in this advisory activity or on the 
group conducting this advisory activity. Oral Statements: In general, 
individuals or groups requesting an oral presentation at a public 
meeting will be limited to five minutes per speaker, with no more than 
a total of one hour for all speakers. Interested parties should contact 
Dr. Shallal, DFO, in writing (preferably via e-mail) at the contact 
information noted above no later than March 26, 2010 to be placed on a 
list of public speakers for the meeting. Written Statements: Written 
statements should be received in the SAB Staff Office by March 29, 2010 
so that the information may be made available to the chartered SAB 
members for their consideration and placed on the SAB Web site for 
public information. Written statements should be supplied to the DFO in 
the following formats: one hard copy with original signature, and one 
electronic copy via e-mail (acceptable file format: Adobe Acrobat PDF, 
WordPerfect, MS Word, MS PowerPoint, or Rich Text files in IBM-PC/
Windows 98/2000/XP format). Submitters are asked to provide versions of 
each document submitted with and without signatures, because the SAB 
Staff Office does not publish documents with signatures on its Web 
sites.
    Accessibility: For information on access or services for 
individuals with disabilities, please contact Dr. Sue Shallal at (202) 
343-9977, or <a href="/cdn-cgi/l/email-protection" class="__cf_email__" data-cfemail="285b404944444944065b5d4049415a684d5849064f475e">[email protected]</a>. To request accommodation of a 
disability, please contact Dr. Shallal, preferably at least 10 days 
prior to the meeting, to give EPA as much time as possible to process 
your request.

    Dated: February 22, 2010.
Anthony Maciorowski,
 Deputy Director, EPA Science Advisory Board Staff Office.
[FR Doc. 2010-4138 Filed 2-26-10; 8:45 am]
BILLING CODE 6560-50-P


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