## Support D ocuments for

Significant New Use Rule (SNUR s ) on

Premanufacture Notice s (PMN s)

P-01-384 , P -01-385, P-01-386,

P-01- 387, and P -01-388

EPA Docket EPA

- HQ

- OPPT

- 201 1-0577

## Index

A-001 Structure Activity Team (SAT) Report for

PMNs P-01- 384, P -01- 385, P -01-386,

P-01- 387, and P-01-388

A-002 Initial Review Engineering Report for

PMNs P-01- 384, P -01- 385, P -01-386,

P-01- 387, and P -01-388

A-003 Initial Review Exposure Report for

PMNs P-01- 384, P -01- 385, P -01-386,

P-01- 387, and P -01-388

## A-001

Structure Activity Team (SAT) Report

for PMNs P-01- 384, P -01- 385, P -01-386,

P-01- 387, and P -01-388

## A-002

Initial Review Engineering Report

for PMNs P-01- 384, P -01- 385, P -01-386,

P-01- 387, and P -01-388**FINAL-Revised 8/9/01**

**Changes are in bold.**

INITIAL REVIEW ENGINEERING REPORT

PMN: 01-384, 385, 386, 387 & 388 ENGINEER: Hall/TMB

PV (kg/yr):

SUBMITTER:

USE:

OTHER USES: None found.

MSDS: Yes Label: No

General Eqp.:

Respirator:

Health Effects:

TLV/PEL (PMN or raw materials):

CRSS: (same for all chemicals)

Chemical Category:

VP: <1E-06 torr @25  C

S-H 2 O: d ersible

MW:

Phys State: Neat: solid (est); Mfg:

Proc/Form:

; End Use:

Consumer Use: No

SAT (concerns):

Related cases:

Ground Water: negligible

Health: 385, 386, 387: 1 no

384, 388: 1-2 inhalation, dermal, ingestion,

Eco: All: 2 all exposures needed for

environmental risk

PBT: P2B1T1OCCUPATIONAL EXPOSURE RATING: 2-3INITIAL REVIEW ENGINEERING REPORT Page # 3

PMN: 01-384, 385, 386, 387 & 388

ASSUMPTIONS: The submission does not indicate if the production

volume is for a combination of the substances or for each individual

substances, therefore assessed as if any one substance is produced

at the production volume. All release and exposure estimates are

applicable to all PMN substances, unless otherwise noted.

PREVENTION CONSIDERATIONS:INITIAL REVIEW ENGINEERING REPORT Page # 4

PMN: 01-384, 385, 386, 387 & 388

EXPOSURE-BASED REVIEW

EXPOSURE-BASED REVIEWINITIAL REVIEW ENGINEERING REPORT Page # 5

PMN: 01-384, 385, 386, 387 & 388

MFG:

Site/Location:

Days/yr:

Process Description:

ENVIRONMENTAL RELEASES (Eqpt. cleaning, container residue, etc.):

**NOTE:**

from:

to:

basis:

OCCUPATIONAL EXPOSURE

Tot. # of workers: (submission)

Days/yr: (submission, based on one day per

batch)

Inhalation: negligible (VP < 0.001 torr )

Dermal with : 900 mg/day

Basis:

Note:INITIAL REVIEW ENGINEERING REPORT Page # 6

PMN: 01-384, 385, 386, 387 & 388

PROC:

Site/Location: (submission)

Days/yr: (submission)

Process Description:

ENVIRONMENTAL RELEASES (Eqpt. cleaning, container residue, etc.):

OCCUPATIONAL EXPOSURE

Tot. # of workers: (submission)

Days/yr:

Inhalation: negligible (VP < 0.001 torr

Dermal : 900 mg/day

Basis:INITIAL REVIEW ENGINEERING REPORT Page # 7

PMN: 01-384, 385, 386, 387, 388

USE:

Site/Location:

Days/yr:

Process Description:

ENVIRONMENTAL RELEASES (Eqpt. cleaning, container residue, etc.):

from:

basis:

OR

from:INITIAL REVIEW ENGINEERING REPORT Page # 8

PMN: 01-384, 385, 386, 387, 388

USE: (cont)

OCCUPATIONAL EXPOSURE

Tot. # of workers:

Days/yr:

Inhalation:

<3.8 mg/day (upper limit)

<0.2 mg/day (lower limi

Number of w

Basis:

Note:

Dermal with : 110 mg/day

Basis:

## A-003

Initial Review Exposure Report

for PM Ns P-01- 384, P -01- 385, P -01-386,

P-01- 387, and P -01-3888/15/01 FINAL Page 1 of 1

POST FOCUS EXPOSURE REPORT

P-01-384c Reviewer: Wormell/Flessner

No exposure assessment needed; the revised engineering report dropped the original

release amount was below assessment threshold.