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                            Funding & Awards
 Interpretation of Y chromosome STRs for missing persons cases
Award Information
Awardee
              UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH
Award #
              2020-DQ-BX-0018
Funding Category
              Competitive Discretionary
Location
                    FORT WORTH, TX
Congressional District
              12
Status
              Closed
Funding First Awarded
              2020
Total funding (to date)
              $198,362
Original Solicitation
              Research and Evaluation for the Testing and Interpretation of Physical Evidence in Publicly Funded Forensic Laboratories, Fiscal Year 2020
Description of original award (Fiscal Year 2020, $198,362)
Y chromosome STR haplotypes (Y-STRs) have been used in assisting forensic investigations primarily for identification and male lineage determination. However, because of the high mutation rate of Y-STRs, there are complex missing person cases in which inconsistent Y-STR haplotypes between true paternal lineage relatives will arise and cases with two or more male references in the same lineage and yet differ in their haplotypes. Therefore, improved guidelines are needed for interpretation of Y-STR haplotype data. Computational methods and interpretation guidelines
have been developed specifically addressing this issue, either using a mismatch based counting method or a pedigree likelihood ratio method. However, these methods and guidelines have not been adopted by forensic laboratories, likely because of a lack of specific procedures and software to facilitate analyses.
This proposed project will validate and implement methods and guidelines for Y-STR applications, particularly for complex missing persons cases. A software program will be developed and validated to facilitate Y-STR haplotype interpretation, and the software will be made accessible to the forensic community free of charge with the goal of improving the interpretation of complex cases with Y-STR
haplotype evidence.
Note: This project contains a research and/or development component, as defined in applicable law, and complies with Part 200 Uniform Requirements - 2 CFR 200.210(a)(14). CA/NCF



  
Grant-Funded Publications
        
                      MPKin-YSTR: Interpretation of Y chromosome STR haplotypes for missing persons cases
                  Interpretation of Y Chromosome STRs for Missing Persons Cases

  
Date Created: October 22, 2020
    
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