U.S. flag
      An official website of the United States government, Department of Justice.
        Here's how you know
      Here's how you know**Official websites use .gov**
            
            A **.gov** website belongs to an official government organization in the United States.
      **Secure .gov websites use HTTPS**
            
            A **lock** (
            A locked padlock
            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites. Menu

      
        close

            
            
                                              About NIJ
        
                    
  
          About NIJ
      
    
          The NIJ Director
          How NIJ Is Organized
          Mission and Guiding Principles
          Research and Development Process
          Strategic Framework
          Assessments of NIJ
          Annual Reports & Reports to Congress
          Staff Directory
          Funding & Awards
        
                    
  
          Funding & Awards
      
    
          Current Funding
          Forthcoming Funding
          Expired Funding
          Awards: Listing of Funded Projects
          Guidance for Applicants and Awardees
          Fellowship & Student Programs
          Travel Scholarships
          NIJ Challenge Program
          Library & Multimedia
        
                    
  
          Library & Multimedia
      
    
          NIJ Journal
          Podcasts
          Publications Listing
          Multimedia Listing
          Rated Practices on CrimeSolutions
          Rated Programs on CrimeSolutions
          Software & Databases
          Datasets
          Patents
          Topics
        
                    
  
          Topics
      
    
          Article Listing
          Corrections
          Courts
          Crime Prevention
          Crimes
          Drugs and Crime
          Equipment and Technology
          Forensic Sciences
          Youth Justice
          Justice System Reform
          Law Enforcement
          Tribal Crime and Justice
          Victims of Crime
          Events
        
                    
  
          Events
      
    
          NIJ 2024 Research Conference
          Scheduled Events
          On-Demand Events
          Research Meetings & Workshops
          NIJ-Hosted Online Training

                            
                                About
          Contact Us
          Subscribe
          Topics A-Z
                  Share
FacebookXLinkedInRedditPinterestEmail Home
                            Funding & Awards
 Forensic Identification of an Individual in Complex Mixtures Utilizing SNP Technology
Award Information
Awardee
              Orchid Cellmark
Award #
              2011-DN-BX-K555
Funding Category
              Competitive
Location
                    Dallas, TX
Congressional District
              24
Status
              Closed
Funding First Awarded
              2011
Total funding (to date)
              $224,968
Original Solicitation
              NIJ FY 11 Applied Research and Development in Forensic Science for Criminal Justice Purposes
Description of original award (Fiscal Year 2011, $224,968)
This research will develop a method using a SNP assay based on the recent work elucidating a novel strategy for identification of an individual's DNA in a complex mixture composed of up to 10 individuals. This strategy employs genotyping a DNA mixture and a 'suspect' DNA sample with 1000-3000 SNPs. The statistical framework shows that this number of markers produces the statistical power required for accurate assessment and inclusion/exclusion of a single contributor in a complex mixture.  The research aims to develop and thoroughly test the feasibility of this strategy utilizing Illumina's GoldenGate(R) genotyping technology, a SNP genotyping technology commonly utilized by the forensic community.  Researchers will test and optimize a pre-selected SNP panel.  Following optimization of the SNP panel, thorough testing of detection limits, sensitivity, and reproducibility studies will be performed prior to testing complex mixtures containing between 3-10 individuals.  ca/ncf



  
Grant-Funded Publications
        
                      SNP-microarrays Can Accurately Identify the Presence of an Individual in Complex Forensic DNA Mixtures

  
Date Created: September 11, 2011
    
          Side navigation
  

        

  
  
              Current Funding
    
      
            
            
            
      Forthcoming Funding
    
      
            
            
            
      Expired Funding
    
      
            
            
            
      Awards: Listing of Funded Projects
    
      
            
            
            
      Guidance for Applicants and Awardees
    
      
            
            
            
      Fellowship & Student Programs
    
      
            
            
            
      Travel Scholarships
    
      
            
            
            
      NIJ Challenge ProgramSimilar Awards
        
                      Experimental and numerical investigations for the development and validation of thermo-chemistry models and property databases for selected wall lining materials under fire exposure
                  Quantitative Assessment of Fracture Characteristics in Blunt Force Skeletal Trauma for Forensic Interpretations
                  Using Community-Based Participatory Research to Advance Transformative Credible Messenger Mentoring for Justice-Involved Youth of Color
 Top

      National Institute of Justice

        
        
                        About NIJ
                    About NIJ
      
    
                  How NIJ Is Organized
      
    
                  NIJ Director
      
    
                  Research Disclaimer
      
    
                  Funding & Awards
                    Funding & Awards Home
      
    
                  Awards Listing
      
    
                  Current Funding
      
    
                  Guidance for Applicants and Awardees
      
    
                  Resources
                    Events
      
    
                  Podcasts
      
    
                  Publications
      
    
                  Topics
      
    
                  Multimedia
      
    
                  Reuse Policy
      
    
                  Contacts
                    Contact NIJ
      
    
                  Staff Directory
      
    
                  Submit a FOIA Request
      
    
                  File a Civil Rights ComplaintFacebook
          
                      X
          
                      YouTube
  

      810 7th St. NW, Washington, D.C. 20531
      
              Secondary Footer link menu
            Accessibility
              Plain Language
              Privacy Policy
              Legal Policies and Disclaimer
              No FEAR Act
              Freedom of Information Act
              USA.gov
              Justice.gov