### DRAFT Agenda **Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel Meeting**  **January 31 -**  **February 2, 2012 Scientific Issues Associated with**  **Common Effects Methodology developed by**

**the Office of Pesticide Programs and the Office of Water**  **Docket number: EPA -** **HQ -**  **OPP -**  **2011 -**  **0898 OPP Docket Tel: 703**  **- 305**  **- 5805**  **Please note that all tim es are approximate**  **(See note at the end of the Agenda) Tuesday, January 31, 2012**  **9:00 A.M. Opening of Meeting and Administrative Procedures** 

– Sharlene Matten, Ph.D.

Designated Federal Official, Office of Science Coordination and Policy, EPA **9:05 A.M. Introduction and Identification of Panel Members** 

– Janice Chambers, Ph.D.,

DABT, FIFRA Scientific Advisory Panel, Session Chair **9: 1**  **5 A.M. Opening Remarks** 

– Donald Brady, Director, Environmental Fate and Effects

Division, Office of Pesticide Programs , EPA and Elizabeth Behl, Ph.D., Director, Office of Science and Technology, Office of Water, EPA **9:30 A.M. Introduction, Background**  **, Statu**  **s , and OPP and OW Data Requirements** 

**and Effects Characterizations**

– Kris Garber, Environmental Fate and Effects Division, Office of Pesticide Programs , EPA and Joe Beaman , Ph.D., Office of Science and Technology, Office of Water, EPA **1 0:15**  **A.M. Break**  **10:30 A.M.**  **Potential Use of Predictive Toxicology Tools in Characterizing Effects of** 

**Chemical Stressors to Aquatic Animals**

**–** Chris Russom, Ph.D., Mid
- Continent Ecology Division, Office of Research and Development, EPA **11: 0**  **0 A.M.**  **Analysis of Sensitivity Distributions for Estimation of Acute Hazard** 

**Concentrations to Aquatic Animals**

**–** Matthew Etterson , Ph.D., Mid
- Continent Ecology Division, Office of Research and Development, EPA **12: 15**  **P. M.**  **Lunch**2

**1: 15**  **P. M.**  **Extrapolation Factors for Derivat ion of Acute Aq**  **uatic Life HC5s :**  **Emphasis**

**on Acetylcholinesterase Inhibitors**

**–** Russell Erickson , Ph .D., Mid
- Continent Ecology Division, Office of Research and Development, EPA **2: 15**  **P. M.**  **Analysis of Chr onic Toxicity Data and Acute Chronic Ratios (ACRs) in** 

**Support of Deriving Chronic HC5s: Acetylcholinesterase Inhibitors**

**–** David Mount, Ph .D., Mid
- Continent Ecology Division, Office of Research and Development, EPA **3:00 P.**  **M. Break**  **3: 15**  **P. M.**  **Estimating Aquatic Plant Community Hazard Concentrations for Pesticide**

**Effects**

**–** Glen Thursb y, Ph.D., Atlantic Ecology Division, Office of Research and Development, EPA **5: 00**  **P. M.**  **Adjournment Wednesday, February 1, 2012**  **9:00 A.M. Opening of Meeting and Administrative Procedures** 

– Sharlene Matten, Ph.D.,

Designated Federal Official, Office of Science Coordination and Policy, EPA **9:05 A.M. Introduction a**  **nd Identification of Panel Members**

– Janice Chambers, Ph.D.,

DABT, FIFRA Scienti fic Advisory Panel, Session Chair **9:10 A.M. Follow** **- up f**  **rom Previous Day’s Meeting**

– Kris Garber, Ph.D., Office of Pesticide Programs , EPA **9:20 A.M. Public Comments**  **10:30 A.M.**  **Break 10**  **: 45**  **A.M. Charge**  **Issue 1**  **: Quantitative Structural Activity Relationship Models** 

**( QSARs**  **) f** 

**or Predicting Acute Toxicity f**  **or Aquatic Animals 12:**  **00 P.**  **M. Lunch**  **1: 00**  **P. M.**  **Charge Issue**  **2 :**  **Web -** **based Interspecies Correlation Estimation M**  **odels**

**( Web**  **- ICE**  **) f** 

**or Predicting Acute Toxicity f**  **or Aquatic Animals**  **2: 00**  **P. M.**  **Charge Issue**  **3: Use o**  **f S**  **pecies S**  **ensitivity D**  **istributions (SSDs)**  **w ith Varying** 

**Am ounts**  **of Empirical Data of Estimate t he**  **HC5 ( the**  **5 -** **th Percentile of the**  **SSD) 3:**  **00 P.**  **M. Break** 3

**3: 15**  **P. M.**  **Charge Issue**  **4 :**  **Extrapolation Factors for E stimating**  **HC5 with a Specified** 

**Level of C onfidence**  **4:30 P.**  **M. Charge**  **Issue 5**  **: Use**  **o f**  **Acute -**  **Chronic Ratios (ACRs) t o Estim**  **ate Chronic**

**Toxicity Endpoints o r**  **HC5 Values f**  **or Acutely Sensitive Species 5:30 P.M.**  **Adjournment Thursday, February 2, 2012**  **9:00 A.M.**  **Opening of Meeting and Administrative Procedures**

– Sharlene Matten, Ph.D.,

Designated Federal Official, Office of Science Coordination and Policy, EPA **9:05 A.M.**  **Introduction and Identification of Panel Members**

– Janice Chambers, Ph.D.,

DABT, FIFRA S cientific Advisory Panel , Session Chair **9:10 A.M.**  **Follow -**  **up From Previous Day’s Meeting**

– Kris Garber, Ph.D., Office of

Pesticide Programs , EPA **9:20 A.M.**  **Panel Discussion of Charge Question 5 cont’d**  **10:30 A.M.**  **Break 10:45 A**  **.M. Charge**  **Issue 6:**  **Estimating the HC5 for Aquatic P** **lants 12:3**  **0 P.M. Lunch**  **1:30 P.M. Continued**  **Panel Discussion**  **(as necessary) 3:00 P.M.**  **Adjournment** Please be advised that agenda times are approximate; when the discussion for one topic is completed, discussions for the next topic will begin. For further information, please contact the Designated Federal Official for this meeting, Dr. Sharlene Matten , telephone: (202)
- 564
- 0130, fax: (202) 564
- 8382, or email: matten.sharlene@epa.gov.