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|   | 1. | Acknowledgement of Assignment of Agreement. Kamada hereby acknowledges and consents to the assignment of the Agreement by Baxter Healthcare SA to Baxalta. Baxalta hereby accepts all of the terms and conditions of the Agreement. All mentions of “Baxter” in the Agreement are amended to read “Baxalta”. |
|--------|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 2. | Section 1.68 of the Agreement is amended to read as follows: |
|--------|----|--------------------------------------------------------------|

|   | 3. | Section 5.3 of the Agreement is amended to read as follows: |
|--------|----|-------------------------------------------------------------|

| [*****] Confidential portions of this document have been redacted and filed separately with the Securities and Exchange Commission.Second Amendment to the Technology License Agreement |   |
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| Milestone | Milestone Payment (USD) |
|-----------|-------------------------|
| [*****]   | [*****][PAID]           |
| [*****]   | [*****][PAID]           |
| [*****]   | [*****][PAID]           |
| [*****]   | [*****]                 |
| [*****]   | [*****]                 |

|   | 4. | All provisions of the Agreement which are not expressly amended by the terms of this Second Amendment shall remain in effect and without change. |
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| BAXALTA GMBH                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          | KAMADA LTD.                                                                                                                                                                                                                                                                                                                                                                                |
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| By: /s/ Stasia L. Ogden                                           Name:  Stasia L. OgdenTitle:  Associate General CounselDate: Aug 25, 2015                                                        | By: /s/ Amir London                                            Name: Amir LondonTitle:  Chief Executive OfficerDate: August 25, 2015            |
| By: /s/ Michael K. Kirschner                                            Name:  Michael K. KirschnerTitle:  Assistant General CounselDate: August 25, 2015                                                                                                      | By: /s/ Gil Efron                                            Name: Gil EfronTitle:  Deputy CEO and Chief Financial OfficerDate: August 25, 2015 |

| [*****] Confidential portions of this document have been redacted and filed separately with the Securities and Exchange Commission.Second Amendment to the Technology License Agreement | Page 2 |
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