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                            Funding & Awards
 Assessing Deep Sequencing Technology for Human Forensic mitochondrial DNA
Award Information
Awardee
              Western Carolina University
Award #
              2010-DN-BX-K171
Funding Category
              Competitive
Location
                    Cullowhee, NC
Awardee County
              Jackson
Congressional District
              11
Status
              Closed
Funding First Awarded
              2010
Total funding (to date)
              $397,098
Original Solicitation
              NIJ FY 10 Forensic DNA Research and Development
Description of original award (Fiscal Year 2010, $397,098)
The researchers propose to evaluate two newly emerging methods of DNA sequence analysis to obtain massively parallel mtDNA sequence information (deep sequencing) from hair, buccal, and blood samples. The expanded information available from deep mtDNA sequence analysis will reveal whether or not interpretational changes in forensic mtDNA analysis of such samples are necessary, as well as the extent to which deep sequencing can offer a window into a level of variation that is currently underappreciated in forensic casework.  This effort will also reveal the general level of sequence heteroplasmy present in hair samples as compared to blood and buccal samples, all common targets of forensic mtDNA analysis.
ca/ncf



  
Grant-Funded Publications
        
                      Assessing Deep Sequencing Technology for Human Forensic Mitochondrial DNA Analysis
                  Simultaneous Detection of Human Mitochondrial DNA and Nuclear Inserted Mitochondrial-Origin Sequences (NumtS) Using Forensic mtDNA Amplification Strategies and Pyrosequencing Technology

  
Date Created: September 16, 2010
    
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