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                            Funding & Awards
 Population Genetic Issues for Forensic DNA Profiles
Award Information
Awardee
              University of Washington
Award #
              2014-DN-BX-K028
Funding Category
              Competitive
Location
                    Seattle, WA
Awardee County
              King
Congressional District
              7
Status
              Closed
Funding First Awarded
              2014
Total funding (to date)
              $510,045
Original Solicitation
              NIJ FY 14 Research and Development in Forensic Science for Criminal Justice Purposes
Description of original award (Fiscal Year 2014, $510,045)
As submitted by the proposer: This application is for continued support of a highly productive team of statistical geneticists, forensic scientists and statisticians at the University of Washington and the Institute of Environmental Science and Research in New Zealand. 

These four investigators will continue working to produce statistical procedures for providing quantitative strength to DNA evidence. Their work will extend population genetic theory for accommodating population structure in calculating match probabilities for autosomal and lineage markers, and combinations of these markers. They will also employ advanced statistical procedures for using peak heights in electropherograms in order to accommodate allelic drop-out and drop-in in situations with single or multiple contributors, and for autosomal as well as lineage markers.

The new statistical techniques to be developed will be applied to publicly-available datasets, including those maintained by the National Institute for Standards and Technology.

The primary outcome of the proposed work will be peer-reviewed publications, although the work will inform the investigators' many teaching activities and service on forensic advisory panels.
ca/ncf



  
Grant-Funded Publications
        
                      Advancing the Statistical Interpretation of Forensic DNA Data Samples
                  Combating Transnational Organized Crime by Linking Multiple Large Ivory Seizures to the Same Dealer
                  Implementation and Validation of an Improved Allele Specific Stutter Filtering Method for Electropherogram Interpretation
                  Likelihood Ratio Development for Mixed Y-STR Profiles
                  Internal Validation of STRmix (TM) - A Multi Laboratory Response to PCAST
                  Population Genetic Issues for Forensic DNA Profiles
                  Internal Validation of STRmix (TM) for the Interpretation of Single Source and Mixed DNA Profiles
                  The Factor of 10 in Forensic DNA Match Probabilities
                  Importance Sampling Allows H-d True Tests of Highly Discriminating DNA Profiles
                  A Unified Characterization of Population Structure and Relatedness
                  Does the Use of Probabilistic Genotyping Change the Way We Should View Sub-threshold Data?
                  Likelihood Ratio Formulae for Disputed Parentage When the Product of Conception Is Trisomic
                  Population Data on the Expanded CODIS Core STR Loci for Eleven Populations of Significance for Forensic DNA Analyses in the United States
                  Admitting to uncertainty in the LR
                  Evaluation of Forensic DNA Mixture Evidence: Protocol for Evaluation, Interpretation, and Statistical Calculations Using the Combined Probability of Inclusion
                  Population-Specific F-ST Values for Forensic STR Markers: A Worldwide Survey
                  Factors Affecting Peak Height Variability for Short Tandem Repeat Data
                  Using Probabilistic Theory To Develop Interpretation Guidelines for Y-STR Profiles
                  Model-free Estimation of Recent Genetic Relatedness
                  Modern Methods of DNA Interpretation
                  Practical Guide for the Formulation of Propositions in the Bayesian Approach to DNA Evidence Interpretation in an Adversarial Environment
                  Probabilistic Approach for the Interpretation of RNA Profiles as Cell Type Evidence
                  Categorical Methods for the Interpretation of RNA Profiles as Cell Type Evidence and Their Limitations
                  Uncertainty in the Number of Contributors in the Proposed New CODIS Set
                  Do Low Template DNA Profiles Have Useful Quantitative Data?
                  Investigating a Common Approach to DNA Profile Interpretation Using Probabilistic Software
                  Testing Likelihood Ratios Produced From Complex DNA Profiles
                  SNPs and SNVs in forensic science
                  The effect of wild card designations and rare alleles in forensic DNA database searches
                  The Variability in Likelihood Ratios due to Different Mechanisms

  
Date Created: September 11, 2014
    
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