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                            Funding & Awards
 Investigating Unexplained Deaths through Molecular Autopsies
Award Information
Awardee
              City of New York, Office of Chief Medical Examiner
Award #
              2011-DN-BX-K535
Funding Category
              Competitive
Location
                    New York, NY
Congressional District
              11
Status
              Closed
Funding First Awarded
              2011
Total funding (to date)
              $696,879
Original Solicitation
              NIJ FY 11 Basic Scientific Research to Support Forensic Science for Criminal Justice Purposes
Description of original award (Fiscal Year 2011, $696,879)
In this application, the researchers propose to sequence the entire coding regions of 52 candidate genes believed to be involved in sudden unexplained deaths in 200 samples, as well as sequence all identified variants in an additional 50 cases and 1,000 gender and ethnically matched controls. Data will be evaluated for new variants as well as combinations of variants that alone may not be disease causing, but in concert may predispose victims to sudden death. To achieve these goals, the authors propose to use the massive parallel sequencing technology available in next generation sequencing platforms.

ca/ncf



  
Grant-Funded Publications
        
                      Genetic Variants Linked to Sudden Unexplained Deaths
                  Investigating Unexplained Deaths for Molecular Autopsies
                  Applying High-Resolution Variant Classification to Cardiac Arrhythmogenic Gene Testing in a Demographically Diverse Cohort of Sudden Unexplained Deaths
                  Holistic Approach to Determine Cause of Autopsy-Negative Sudden Natural Death
                  Cardiac Channelopathy Testing in 274 Ethnically Diverse Sudden Unexplained Deaths

  
Date Created: September 15, 2011
    
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