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|  | 1. | Capitalized terms not otherwise defined in this Amendment shall have the same meaning as ascribed to them in the Agreement. |
|--|----|-----------------------------------------------------------------------------------------------------------------------------|

|  | 2. | Except as specifically set forth herein in this Amendment, the terms and conditions of the Agreement remain in full force and effect. |
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|  | 3. | Section 1.46 of the Agreement is amended to read as follows: |
|--|----|--------------------------------------------------------------|

|  | (a) | Two Surgeon Leads |
|--|-----|-------------------|

|  | (b) | One Surgeon Leads |
|--|-----|-------------------|

|  | (c) | Collaboration Leads |
|--|-----|---------------------|

|  | (d) | Lead Cap |
|--|-----|----------|

|  | 4. | A new Section 1.60 is added to the Agreement: |
|--|----|-----------------------------------------------|

|  | 1.60. | “Two-Surgeon Lead” means a sales account with respect to which [THE CONFIDENTIAL PORTION HAS BEEN SO OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND HAS BEEN FILED SEPARATELY WITH THE COMMISSION] |
|--|-------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|  | 5. | A new Section 1.61 is added to the Agreement: |
|--|----|-----------------------------------------------|

|  | 1.61 | “One-Surgeon Lead” means a sales account with respect to which at least [THE CONFIDENTIAL PORTION HAS BEEN SO OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND HAS BEEN FILED SEPARATELY WITH THE COMMISSION] |
|--|------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 6. | A new Section 1.62 is added to the Agreement: |
|--|----|-----------------------------------------------|

|  | 1.62 | “Collaboration Lead” [THE CONFIDENTIAL PORTION HAS BEEN SO OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND HAS BEEN FILED SEPARATELY WITH THE COMMISSION] |
|--|------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | 7. | Section 4.1 of the Agreement is amended to read as follows: |
|--|----|-------------------------------------------------------------|

|  | 4.1 | Generation of Qualified Leads.  During the U.S. Lead Generation Period, Medtronic will generate and provide to Mazor Two-Surgeon Leads and One-Surgeon Leads, and work together with Mazor on Collaboration Leads, in accordance with Applicable Laws and the terms and conditions of this Agreement and the Medtronic Sales and Marketing Plan (“Lead Generation Services”).  Mazor acknowledges that Medtronic does not guarantee the success of the Lead Generation Services or that the Lead Generation Milestone Amount will be obtained as a result of Medtronic’s efforts.  Medtronic will provide Mazor with a quarterly report detailing the Lead Generation Services. |
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|  | 8. | Section 4.4(a) of the Agreement is amended to read as follows: |
|--|----|----------------------------------------------------------------|

|  | 4.4 (a) | Lead Generation Fees.  With respect to each sale of a MazorX System during the Lead Generation Period resulting from a Two-Surgeon Lead, a One-Surgeon Lead or a Collaboration Lead, Mazor will pay to Medtronic a fee (a “Lead Generation Fee”) equal to the greater of (i) [THE CONFIDENTIAL PORTION HAS BEEN SO OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND HAS BEEN FILED SEPARATELY WITH THE COMMISSION] and (ii) an amount equal to twenty-five percent (25%) of the Net Sales received by such sale.  Once Mazor has paid Medtronic [THE CONFIDENTIAL PORTION HAS BEEN SO OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND HAS BEEN FILED SEPARATELY WITH THE COMMISSION] Lead Generation Fees, for each additional sale of a MazorX System during the Lead Generation Period resulting from a Two-Surgeon Lead, a One-Surgeon Lead or a Collaboration Lead, Mazor will pay to Medtronic a fee equal to the greater of (i) [THE CONFIDENTIAL PORTION HAS BEEN SO OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND HAS BEEN FILED SEPARATELY WITH THE COMMISSION] and (ii) an amount equal to twelve-and-one-half percent (12.5%) of the Net Sales received by such sale.  No Lead Generation Fee shall be payable with respect to any Demo Units or any Initial Placed Unit even if such unit is sold to a customer. |
|--|---------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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| MEDTRONIC NAVIGATION, INC. By: /s/ Scott Hutton Name: Scott Hutton Title: VP/ GM Date: October 31, 2016 |   | MAZOR ROBOTICS LTD. By: /s/ Jonathan Adereth Name: Jonathan Adereth Title:  Chairman of the Board of Directors Date:  October 24, 2016 |
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|                                                                                                                        |   |                                                                                                                                                                 |
|                                                                                                                        |   | By: /s/ Ori Hadomi Name: Ori Hadomi Title: Chief Executive Officer Date:  October 24, 2016                                                       |

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