| **EXHIBIT 32.1  CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED  PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002**                                                                                                                                                                                                                                                                                                                                                                                                       |
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |
|      In  connection with the quarterly report of CNB Corporation on Form 10-Q for the  period ending March 31, 2005 as filed with the Securities and Exchange  Commission on the date hereof, W. Jennings Duncan, President and Chief  Executive Officer and Paul R. Dusenbury, Treasurer and Chief Financial  Officer, of the CNB Corporation, each certifies to the best of his knowledge,  pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the  Sarbanes-Oxley Act of 2002 that:

  |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | 1. | The  above-referenced Form 10-Q fully complies with the requirements of Section  13(a) or 15(d) of the Securities Exchange Act of 1934; and |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |  |  |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | 2. | The  information contained in the above referenced Form 10-Q fairly presents, in  all material respects, the financial condition and results of operations of  the Company. |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |
| Date:   May 10, 2005                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | /s/W. Jennings Duncan                        W. Jennings Duncan  President and Chief Executive Officer |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | /s/Paul R. Dusenbury                          Paul R. Dusenbury  Treasurer and Chief Financial Officer |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                |  |  |  |