76460 Federal Register / Vol. 75, No. 235 / Wednesday, December 8, 2010 / Notices 

approach may allow estimation of dataderived uncertainty factors that consider 

use of toxicokinetic and toxicodynamic 

data to inform quantitative 

extrapolations for interspecies 

differences and human variability in 

dose response assessment. The topics to 

be covered in the February 2011 SAP 

are consistent with EPA’s Office of 

Pesticide Programs continuing efforts to 

improve the scientific basis for risk 

assessment by broadening the 

application of probabilistic exposure 

techniques and PBPK models. The 

Agency has a conceptually similar effort 

on-going to link PBPK models for 

pyrethroids with Stochastic Human 

Exposure and Dose Simulator (SHEDS) 

exposure software, a probabilistic 

exposure model developed by the EPA’s 

Office of Research and Development, 

which was reviewed by the SAP in July 

2010. The current effort by Dow 

AgroSciences is a research effort which 

may, if sufficiently robust, inform future 

risk assessments; the February meeting 

is a key milestone in this research. The 

Agency will solicit feedback from the 

Panel on technical issues related to 

PBPK/PD model, the proposed approach 

for merging the PBPK/PD model with 

CARES, and the use of such merged 

models in risk assessment. 

C. FIFRA SAP Documents and Meeting 

Minutes 

EPA’s background paper, related 

supporting materials, charge/questions 

to FIFRA SAP, FIFRA SAP composition 

(i.e., members and ad hoc members for 

this meeting), and the meeting agenda 

will be available by late January 2011. 

In addition, the Agency may provide 

additional background documents as the 

materials become available. You may 

obtain electronic copies of these 

documents, and certain other related 

documents that might be available 

electronically, at http:// 

www.regulations.gov and the FIFRA 

SAP homepage at http://www.epa.gov/ 

scipoly/sap. 

FIFRA SAP will prepare meeting 

minutes summarizing its 

recommendations to the Agency 

approximately 90 days after the 

meeting. The meeting minutes will be 

posted on the FIFRA SAP Web site or 

may be obtained from the OPP 

Regulatory Public Docket at http:// 

www.regulations.gov. 

List of Subjects 

Environmental protection, Pesticides 

and pests. 

Dated: November 23, 2010. 

Frank Sanders, 

Director, Office of Science Coordination and 

Policy. 

[FR Doc. 2010–30630 Filed 12–7–10; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[FRL–9236–6; Docket ID No. EPA–HQ–ORD– 

2010–0991] 

Lymphohematopoietic Cancers 

Induced by Chemicals and Other 

Agents: Overview and Implications for 

Risk Assessment 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice of public comment 

period. 

SUMMARY: EPA is announcing a 45-day 

public comment period for the draft 

document titled, 

‘‘Lymphohematopoietic Cancers 

Induced by Chemicals and Other 

Agents: Overview and Implications for 

Risk Assessment’’ (EPA/600/R–10/ 

095A). The draft document was 

prepared by the National Center for 

Environmental Assessment within 

EPA’s Office of Research and 

Development. The draft document 

provides an overview of the types and 

mechanisms underlying the 

lymphohematopoietic cancers induced 

by chemical agents and radiation in 

humans, with a primary emphasis on 

leukemia and leukemia-inducing agents. 

In addition, the document also focuses 

on how mechanistic information on 

human leukemia-inducing agents can 

inform risk assessment. 

EPA is releasing this draft document 

solely for the purpose of predissemination peer review under 

applicable information quality 

guidelines. This draft document has not 

been formally disseminated by EPA. It 

does not represent and should not be 

construed to represent any Agency 

policy or determination. All public 

comments received will be provided to 

the peer reviewers at the beginning of 

the review process. 

DATES: The 45-day public comment 

period begins December 8, 2010, and 

ends January 24, 2011. Technical 

comments should be in writing and 

must be received by EPA by January 24, 

2011. 

ADDRESSES: The draft 

‘‘Lymphohematopoietic Cancers 

Induced by Chemicals and Other 

Agents: Overview and Implications for 

Risk Assessment’’ is available primarily 

via the Internet on the National Center 

for Environmental Assessment’s home 

page under the Recent Additions and 

the Data and Publications menus at 

http://www.epa.gov/ncea. A limited 

number of paper copies are available 

from the Information Management 

Team, NCEA; telephone: 703–347–8561; 

facsimile: 703–347–8691. If you are 

requesting a paper copy, please provide 

your name, your mailing address, and 

the draft document title, 

‘‘Lymphohematopoietic Cancers 

Induced by Chemicals and Other 

Agents: Overview and Implications for 

Risk Assessment.’’ 

Comments may be submitted 

electronically via http:// 

www.regulations.gov, by mail, by 

facsimile, or by hand delivery/courier. 

Please follow the detailed instructions 

provided in the SUPPLEMENTARY

INFORMATION section of this notice. 

FOR FURTHER INFORMATION CONTACT: For 

information on the public comment 

period, contact the Office of 

Environmental Information Docket; 

telephone: 202–566–1752; facsimile: 

202–566–1753; or e-mail: 

ORD.Docket@epa.gov. 

For technical information, contact 

Nagu Keshava, NCEA; telephone: 919– 

541–3047; facsimile: 919–541–0245; or 

e-mail: keshava.nagu@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. Information About the Project/ 

Document 

This project was initiated to better 

understand the mechanisms underlying 

the lymphohematopoietic cancers 

induced by chemical agents in humans. 

A draft report was developed that 

provides an overview of types and 

mechanisms underlying the 

lymphohematopoietic cancers induced 

by both chemical agents and radiation 

in humans, with a primary emphasis on 

leukemia and leukemia-inducing agents. 

II. How to Submit Technical Comments 

to the Docket at http:// 

www.regulations.gov 

Submit your comments, identified by 

Docket ID No. EPA–HQ–ORD–2010– 

0991, by one of the following methods: 

• http://www.regulations.gov: Follow 

the on-line instructions for submitting 

comments. 

• E-mail: ORD.Docket@epa.gov. 

• Fax: 202–566–1753. 

• Mail: Office of Environmental 

Information (OEI) Docket (Mail Code: 

2822T), U.S. Environmental Protection 

Agency, 1200 Pennsylvania Ave., NW., 

Washington, DC 20460. The phone 

number is 202–566–1752. 

• Hand Delivery: The OEI Docket is 

located in the EPA Headquarters Docket 


jlentini on DSKJ8SOYB1PROD with NOTICES
Federal Register / Vol. 75, No. 235 / Wednesday, December 8, 2010 / Notices 76461 

Center, Room 3334 EPA West Building, 

1301 Constitution Ave., NW., 

Washington, DC. The EPA Docket 

Center Public Reading Room is open 

from 8:30 a.m. to 4:30 p.m., Monday 

through Friday, excluding legal 

holidays. The telephone number for the 

Public Reading Room is 202–566–1744. 

Such deliveries are only accepted 

during the docket’s normal hours of 

operation, and special arrangements 

should be made for deliveries of boxed 

information. If you provide comments 

by mail or hand delivery, please submit 

three copies of the comments. For 

attachments, provide an index, number 

pages consecutively with the comments, 

and submit an unbound original and 

three copies. 

Instructions: Direct your comments to 

Docket ID No. EPA–HQ–ORD–2010– 

0991. Please ensure that your comments 

are submitted within the specified 

comment period. Comments received 

after the closing date will be marked 

‘‘late,’’ and may only be considered if 

time permits. It is EPA’s policy to 

include all comments it receives in the 

public docket without change and to 

make the comments available online at 

http://www.regulations.gov, including 

any personal information provided, 

unless a comment includes information 

claimed to be Confidential Business 

Information (CBI) or other information 

whose disclosure is restricted by statute. 

Do not submit information that you 

consider to be CBI or otherwise 

protected through http:// 

www.regulations.gov or e-mail. The 

http://www.regulations.gov Web site is 

an ‘‘anonymous access’’ system, which 

means EPA will not know your identity 

or contact information unless you 

provide it in the body of your comment. 

If you send an e-mail comment directly 

to EPA without going through http:// 

www.regulations.gov, your e-mail 

address will be automatically captured 

and included as part of the comment 

that is placed in the public docket and 

made available on the Internet. If you 

submit an electronic comment, EPA 

recommends that you include your 

name and other contact information in 

the body of your comment and with any 

disk or CD–ROM you submit. If EPA 

cannot read your comment due to 

technical difficulties and cannot contact 

you for clarification, EPA may not be 

able to consider your comment. 

Electronic files should avoid the use of 

special characters, any form of 

encryption, and be free of any defects or 

viruses. For additional information 

about EPA’s public docket visit the EPA 

Docket Center homepage at http:// 

www.epa.gov/epahome/dockets.htm. 

Docket: Documents in the docket are 

listed in the http://www.regulations.gov 

index. Although listed in the index, 

some information is not publicly 

available, e.g., CBI or other information 

whose disclosure is restricted by statute. 

Certain other materials, such as 

copyrighted material, are publicly 

available only in hard copy. Publicly 

available docket materials are available 

either electronically in http:// 

www.regulations.gov or in hard copy at 

the OEI Docket in the EPA Headquarters 

Docket Center. 

Dated: December 2, 2010. 

Darrell A. Winner, 

Acting Director, National Center for 

Environmental Assessment. 

[FR Doc. 2010–30848 Filed 12–7–10; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPP–2010–0548; FRL–8852–8] 

Petition for a Ban on Triclosan; Notice 

of Availability 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: This notice makes available 

for review and public comment a 

petition submitted by Beyond 

Pesticides, and Food & Water Watch 

(hereafter referred to as ‘‘the 

petitioners’’) to the Environmental 

Protection Agency (hereafter referred to 

as ‘‘EPA’’ or ‘‘the Agency’’), asking EPA 

to use its authority under various 

statutes to regulate triclosan. Triclosan 

is an antimicrobial substance used in 

pesticide products, hand sanitizers, 

toothpaste, and other consumer 

products. The petitioners claim that the 

‘‘pervasive and widespread use’’ of 

triclosan poses significant risks to 

human health and the environment. In 

addition, the petitioners claim that the 

agency failed to address the impacts 

posed by triclosan’s degradation 

products on human health and the 

environment, failed to conduct separate 

assessments for triclosan residues in 

contaminated drinking water and food, 

and is complacent in seriously 

addressing concerns related to 

antibacterial resistance and endocrine 

disruption. EPA has established a public 

docket, which contains a copy of the 

petition and will contain all comments 

received in response to this notice. The 

docket may be accessed as described in 

this notice. 

DATES: Comments must be received on 

or before February 7, 2011. 

ADDRESSES: Submit your comments, 

identified by docket identification (ID) 

number EPA–HQ–OPP–2010–0548, by 

one of the following methods: 

• Federal eRulemaking Portal: http:// 

www.regulations.gov. Follow the on-line 

instructions for submitting comments. 

• Mail: Office of Pesticide Programs 

(OPP) Regulatory Public Docket (7502P), 

Environmental Protection Agency, 1200 

Pennsylvania Ave., NW., Washington, 

DC 20460–0001. 

• Delivery: OPP Regulatory Public 

Docket (7502P), Environmental 

Protection Agency, Rm. S–4400, One 

Potomac Yard (South Bldg.), 2777 S. 

Crystal Dr., Arlington, VA. Deliveries 

are only accepted during the Docket 

Facility’s normal hours of operation 

(8:30 a.m. to 4 p.m., Monday through 

Friday, excluding legal holidays). 

Special arrangements should be made 

for deliveries of boxed information. The 

Docket Facility telephone number is 

(703) 305–5805. 

Instructions: Direct your comments to 

docket ID number EPA–HQ–OPP–2010– 

0548. When commenting, please specify 

the statute to which your comments 

refer (FIFRA, FFDCA, SDWA, CWA, or 

ESA) and the specific issue(s) raised in 

the petition regarding that statute on 

which you are commenting. EPA’s 

policy is that all comments received 

will be included in the docket without 

change and may be made available online at http://www.regulations.gov, 

including any personal information 

provided, unless the comment includes 

information claimed to be Confidential 

Business Information (CBI) or other 

information whose disclosure is 

restricted by statute. Do not submit 

information that you consider to be CBI 

or otherwise protected through 

regulations.gov or e-mail. The 

regulations.gov Web site is an 

‘‘anonymous access’’ system, which 

means EPA will not know your identity 

or contact information unless you 

provide it in the body of your comment. 

If you send an e-mail comment directly 

to EPA without going through 

regulations.gov, your e-mail address 

will be automatically captured and 

included as part of the comment that is 

placed in the docket and made available 

on the Internet. If you submit an 

electronic comment, EPA recommends 

that you include your name and other 

contact information in the body of your 

comment and with any disk or CD–ROM 

you submit. If EPA cannot read your 

comment due to technical difficulties 

and cannot contact you for clarification, 

EPA may not be able to consider your 

comment. Electronic files should avoid 

the use of special characters, any form 


jlentini on DSKJ8SOYB1PROD with NOTICES