INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary. 2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product Registration 5. I wish to cancel this product registration voluntarily 6. Generic Data 7. Product Specific Data 6a. I am claiming a Generic Data Exemption because I obtain the active ingredient from the source EPA registration number listed below. 6b. I agree to satisfy Generic Data Requirements as indicated on the attached form entitled "Requirements Status and Registrant's Response." 7a. My product is an MUP and I agree to satisfy the MUP requirement on the attached form entitled "Requirements Status and Registrant's Response." 7b. My product is an EUP and I agree to satisfy the EUP requirement on the attached form entitled "Requirements Status and Registrant's Response." OMB Approval 2070-0174

1. Company Name and Address 2540 - Profenofos Chemical # and Name: 111401 Profenofos 30-Dec-2009 GENERIC ID # GDCI-111401-870 

### United States Environmental Protection Agency

Washington, D.C. 20460 DATA CALL-IN RESPONSE 1 Page of 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. Signature and Title of Company's Authorized Representative ______________________________________________________ 10. Name of Company N/A N/A

9. Date
11. Phone Number13. Phone Number 10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. 12. Name of Company 11. Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Environmental Fate Data Requirements (Conventional Chemical)

Nontarget Plant Protection Data Requirements (Conventional Chemical) Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical) 835.1230 835.4300

850.4400

850.1400 850.2100 Sediment and soil absorption/desorption for parent

and degradates Aerobic aquatic metabolism
Aquatic plant toxicity test using Lemna spp. Tiers I and II Fish early-life stage toxicity test Avian acute oral toxicity test 2540 - Profenofos Chemical # and Name: 111401 Profenofos 30-Dec-2009 GENERIC ID # GDCI-111401-870

C C

C

C C EP; PAI; TGAI EP; PAI; TGAI
EP; PAI; TGAI

TGAI EP; PAI; TGAI 12 24

12

12 12 1 of Page

(1, 6)

(2)
(3, 4) (5, 7) N

N

N

N Y 2OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Toxicology Data Requirements (Conventional Chemical) 870.7800

830.7050 Immunotoxicity

UV/Vis ble absorption 2540 - Profenofos Chemical # and Name: 111401 Profenofos 30-Dec-2009 GENERIC ID # GDCI-111401-870

C

C TGAI
EP; PAI; TGAI 24

8 2 of Page

N

N 2

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS 2540 - Profenofos GDCI-111401-870

1 2 3 4

5 6 7 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

This study should define Kd and Koc values of this chemical in US soils. Study is required for both lemna and algae. Data are required on one estuarine/marine fish species, preferably sheepshead minnow, Cyprinodon variegatus. Data are required on estuarine species if the product is: (i) intended for direct application to the estuarine or marine environment; (ii) expected to enter this environment in significant concentrations because of its expected use or mobility patterns, and (iii) if the acute LC50 or EC50 < 1 mg/l; or (iv) if the estimated environmental concentration in water is equal to or greater than 0.01 of the acute EC50 or LC50 and any of the following conditions exist: (a) studies of other organisms indicate the reproductive physiology of fish and/or invertebrates may be affected; (b) physicochemical properties indicate bioaccumulation of the pesticide; (c) the pesticide is persistent in water (e.g., half-life in water greater than 4 days). Data are required on a passerine species and either one waterfowl species or one upland game bird species for terrestrial, aquatic, forestry, and residential outdoor uses. Adsorption and desorption using a batch equilibrium method is preferred. However, in some cases, for example, where the pesticide degrades rapidly, soil column leaching with unaged or aged columns may be more appropriate to fully characterize the potential mobility of the parent compound and major transformation products. A passerine study protocol must be submitted for review by the Agency prior to initiation of this study. Case # and Name: DCI Number: 1 Page: of 1

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement. Use Categories Key: C - Terrestrial nonfood crop

### United States Environmental Protection Agency Washington, D.C. 20460 LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE 2540 - Profenofos Case # and Name: 1 Page: of 1

100 SYNGENTA CROP PROTECTION, LLC Co. Nr. Company Name Agent For Company 410 SWING ROAD, P.O. Box 18300 Address City ZIP GREENSBORO 274198300 OMB Approval 2070-0174

State NC DCI Number: GDCI-111401-870

# LINKS TO FORMS: The pesticide registration forms that are listed below can be found at: http://www.epa.gov/opprd001/forms/ Link to C onfidential Statement of Formula and Instructions (Form # 8570 -4 

# ) http://www.epa.gov/opprd001/forms/8570 - 4.pdf C ertification of Attempt to Enter Into an Agreement With Registrants for Development of Data (Form # 8570 - 32 

# ) http://www.epa.gov/opprd001/forms/8570 - 32.pdf C ertification With Respect to Citation of Data (Form # 8570 - 34 

# ) http://www.epa.gov/opprd001/forms/8570 - 34.pdf