Page 1 of 1INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.1. Company Name and Address4. EPA ProductRegistrationOMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460DATA CALL-IN RESPONSE3. Date and Type of DCI and NumberGENERIC23-Feb-2010ID # GDCI-075202-292212. Case # and Name3132 Sodium fluorideChemical # and Name075202Sodium fluoride5. I wish tocancel thisproduct registration voluntarily6. Generic Data7. Product Specific Data7a. My product is an MUP andI agree to satisfy the MUPrequirements on the attachedform entitled "RequirementsStatus and Registrant'sResponse."7b. My product is an EUP andI agree to satisfy the EUPrequirements on the attachedform entitled "RequirementsStatus and Registrant'sResponse."6a. I am claiming a GenericData Exemption because Iobtain the active ingredientfrom the source EPA registration number listed below.6b. I agree to satisfy GenericData requirements as indicatedon the attached form entitled"Requirements Status andRegistrant's Response."N.A.N.A.10. Name of Company11. Phone Number9. Date8. Certification I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that anyknowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.Signature and Title of Company's Authorized Representative__________________________________Sodium fluorideINSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.4. GuidelineRequirementNumber5. Study Title1. Company Name and AddressPage 1 of 1OMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE3. Date and Type of DCI and NumberID #GENERIC23-Feb-2010GDCI-075202-292212. Case # and Name3132 Sodium fluoride075202Chemical # and Name8. TimeFrame(Months)9. RegistrantResponse7. TestSubstance6. UsePatternPROTOCOLProgressReports321Applicator Exposure Data Requirements (Antimicrobial)(2 ,3 ,4)875.110024BBDermal exposure--outdoor(5)875.160024BBApplication exposure monitoring data reportingToxicology Data Requirements (Antimicrobial)(1)870.325024TGAIBB90-day dermal toxicity12. Name of Company13. Phone NumberSignature and Title of Company's Authorized Representative__________________________________10. Certification I certify that the statements made on this form and all attachments are true, accurate, and complete. Iacknowledge that anyknowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law11. DateCase # and Name:3132 Sodium fluorideDCI Number:GDCI-075202-29221Page 1 of 1[The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Footnotes:Key:United States Environmental ProtectionAgency Washington, D.C. 20460FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTSTGAI = Technical Grade Active Ingredient [TGAI]Use Categories Key:BB - Wood preservatives1Required if intended use of the antimicrobial pesticide product is expected to result in human exposure to the product, under the following conditions:(i) Human exposure is via skin contact. (ii)Expected human exposure is not purposeful, and is over a limited portion of the human lifespan, yet is significant in terms ofthe frequency of exposure, magnitude of exposure, or the duration ofexposure. (iii) Data from a subchronic 90-day dermal toxicity study are not required. The EP shall also be tested if any component of the EP may increase dermal absorption of the activeingredient(s) or potentiate toxic or pharmacologic effects.2The Agency will require application exposure data beyond the required product use information (Guideline 875.1700) if at leastone of the following exposure criteria and at least one of thefollowing toxicity criteria are met by the TEP, TGAI, or one of the pesticide's metabolites: (i) Exposure criteria. (A) Dermalexposure is likely to occur during use. (B) Inhalation exposure is likelyto occur during use. (C) Adequate surrogate exposure data (e.g. PHED) to estimate the magnitude of exposure for a particular work activity with an acceptable degree of confidence areunavailable. (ii) Toxicity criteria. (A) The acute dermal LD50 is less than or equal to 200 mg/kg (i.e., Toxicity CategoryI (Guideline 870.1200) as per 40 CFR 156.10). (B) The acute inhalationLC50 (Guideline 870.1300) is less than or equal to 0.05 mg/liter (i.e., 4-hour exposure, Toxicity Category I) and the TGAI hasa vapor pressure greater than 10-3 mm Hg at 25degrees C if usedoutdoors or any indoor application regardless of the vapor pressure. (C) The pesticide is found to be a neurotoxicant (Guideline 870.6200). (D) The pesticide is found to be a developmentaltoxicant (Guidelines 870.3700 and 870.6300). (E) The pesticide is found to be a carcinogen (Guideline 870.4200). (F) The pesticide shows potential adverse effects in subchronic studies suchas 90-day oral (Guideline 870.3100), 21-day repeated dermal toxicity (Guideline 870.3200), 90-day dermal toxicity (Guideline 870.3250), 90-day inhalation (Guideline 870.3465), reproductionand fertility effects (Guideline 870.3800), and chronic feeding (Guideline 870.4100). (G) The pesticide is found to be a mutagen (Guidelines 870.5100 to 870.5900) or an immunotoxicant(Guideline 870.7800). (H) Epidemiological or poisoning incidence data indicate adverse effects from handling the pesticide.3Required for outdoor uses when that is the primary use or if outdoor uses are expected to result in greater exposure than indoor uses.4Protocols must be submitted to the Agency for approval before initiating a study.5Data reporting and calculations are required when exposure data are submitted.United States Environmental ProtectionAgency Washington, D.C. 20460LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICECo. Nr.Company NameAgent ForAddressCity & StateZipCase # and Name:3132,Sodium fluoridePRESCHEM PTY. LTDSCIREG, INC.12733 DIRECTOR'S LOOPWOODBRIDGEVA2219283933OSMOSE INC.980 ELLICOTT STBUFFALONY142093008