# Support Documents for

Significant New Use Rules (SNURs) on

Premanufacture Notices (PMNs)

P-09-152 and P-09-153

EPA Docket EPA-HQ-OPPT-2010-1075

# Index

A-001 Structure Activity Team (SAT) Report s for

PMNs P -09-152 and P -09-153

A-002 Initial Review Engineering Reports for

PMNs P -09-152 and P -09-153

A-003 Initial Review Exposure Reports for

PMNs P -09-152 and P -09-153

# A-001

Structure Activity Team (SAT) Reports

for PMNs P-09-152 and P-09-153

## SAT Report

PMN Number: P-09-0152
SAT Date: 1/16/2009

Related cases : Health related cases:
Ecotox related cases:

Concern levels :



### Type of Concern: Health Eco Comments
Level of Concern: 1-2 2

Persistence Bioaccum Toxicity Comments
2 1 2

Exposure Based Review : Health:
Ecotox: N o

Routes of exposure : Health: Inhalation, drinking water
Ecotox: All releases to water
Fate: ;

P 2 Rec Comments : Comment: SAT had no comment

Keywords : Keywords: DEVEL; MUTA; BLOOD; ONCO; SENS (UNCERT); MALE REPRO (UNCERT); AQUATOX

Summary of Assessment :

Fate : Fate Summary: P-09-0152-53
FATE: Solid S = 75 g/L at 25 C (M) VP < 1.0E-6 torr at 25 EC (E) BP > 400 EC (E) H < 1.00E-8 (E) POTW removal (%) = 0 Time for complete ultimate aerobic biodeg = mo

### Time for primary anaerobic biodeg # da Sorption to soils/sediments = low - moderate
PBT Potential: P2B1 *CEB FATE: Migration to ground water = negl

Health : Health Summary: N ot absorbed from the skin or the GI tract intact, absorbed from the lung ( p che m ); expect dissociation from the 2:1 complex to the 1:1 complex with <5% bioavailability of based on data for expect reduction in both moieties and group reduction for the moieties containing that group; and absorption of the reduction products from the GI tract (analog). Concern for blood toxicity (methemoglobinemia) and uncertain concern for male reproductive toxicity based on submitted test data for Concern for developmental toxicity, mutagenicity, and methemoglobinemia for the reduction product; mutagenicity, oncogenicity, and developmental toxicity for the naphthylamine reduction product based on ; developmental toxicity, mutagenicity, oncogenicity, and blood toxicity for the reduction product. Uncertain concern for developmental toxicity and mutagenicity
for to the extent that it is bioavailable.
Test Data: For (-) Salmonella with and without activation; (-) E. coli with and without activation; (-) for chromosome aberrations in CHL cells with and without activation; rat oral LD0 = 2000 mg/kg; rat dermal LD0 = 2000 mg/kg; slight eye irritation in rabbits, cleared by 48 hours; no skin irritation in rabbits; no skin sensitization in guinea pigs using the Magnusson-Kligman assay; rat 28-day oral NOEL = 200 mg/kg, blood toxicity and discolored organs, including the testes, at 1000 mg/kg

Ecotox :

Test Organism Test Type Test End
Point Predicted Measured Comments

fish 96-h LC50 7.0 daphnid 48-h LC50 7.0 green algal 96-h EC50 3.0 shading

fish

_ chronic value 1.1 daphnid chronic value 1.1 algal

_ chronic value 0.30 shading Sewage Sludge 3-h EC50

_ Sewage Sludge

_ Chronic Value

_
Ecotox Values Comments: Predictions are based on SAR-nearest analog method for and indirect effect of algal shading from the ; SAR chemical class = MW 1026/924; p H7; effective concentrations based on 100% active ingredients and mean measured concentrations; hardness <180.0 mg/L as CaCO3; and TOC <2.0 mg/L;

Factors Values Comments

### Assessment Factor 10
Concentration of Concern ( p pb) 30

SARs
SAR Class

Ecotox Factors Comments:

SAT Chair: L Keifer 564-8916

## SAT Report

PMN Number: P-09-0153
SAT Date: 1/16/2009

Related cases : Health related cases:
Ecotox related cases:

Concern levels :



### Type of Concern: Health Eco Comments
Level of Concern: 1-2 2

Persistence Bioaccum Toxicity Comments
2 1 2

Exposure Based Review : Health:
Ecotox: N o

Routes of exposure : Health: Inhalation, drinking water
Ecotox: All releases to water
Fate: ;

P 2 Rec Comments : Comment: SAT had no comment

Keywords : Keywords: DEVEL; MUTA; BLOOD; ONCO; SENS (UNCERT); MALE REPRO (UNCERT); AQUATOX

Summary of Assessment :

Fate : Fate Summary: P-09-0152-53
FATE: Solid S = 75 g/L at 25 C (M) VP < 1.0E-6 torr at 25 EC (E) BP > 400 EC (E) H < 1.00E-8 (E) POTW removal (%) = 0 Time for complete ultimate aerobic biodeg = mo

### Time for primary anaerobic biodeg # da Sorption to soils/sediments = low - moderate
PBT Potential: P2B1 *CEB FATE: Migration to ground water = negl

Health : Health Summary: N ot absorbed from the skin or the GI tract intact, absorbed from the lung ( p che m ); expect dissociation from the 2:1 complex to the 1:1 complex with <5% bioavailability of based on data for expect reduction in both moieties and group reduction for the moieties containing that group; and absorption of the reduction products from the GI tract (analog). Concern for blood toxicity (methemoglobinemia) and uncertain concern for male reproductive toxicity based on submitted test data for Concern for developmental toxicity, mutagenicity, and methemoglobinemia for the reduction product; mutagenicity, oncogenicity, and developmental toxicity for the reduction product based on ; developmental toxicity, mutagenicity, oncogenicity, and blood toxicity for the reduction product. Uncertain concern for developmental toxicity and mutagenicity
for to the extent that it is bioavailable.
Test Data: For (-) Salmonella with and without activation; (-) E. coli with and without activation; (-) for chromosome aberrations in CHL cells with and without activation; rat oral LD0 = 2000 mg/kg; rat dermal LD0 = 2000 mg/kg; slight eye irritation in rabbits, cleared by 48 hours; no skin irritation in rabbits; no skin sensitization in guinea pigs using the Magnusson-Kligman assay; rat 28-day oral NOEL = 200 mg/kg, blood toxicity and discolored organs, including the testes, at 1000 mg/kg

Ecotox :

Test Organism Test Type Test End
Point Predicted Measured Comments

fish 96-h LC50 7.0 daphnid 48-h LC50 7.0 green algal 96-h EC50 3.0 shading

fish

_ chronic value 1.1 daphnid chronic value 1.1 algal

_ chronic value 0.30 shading Sewage Sludge 3-h EC50

_ Sewage Sludge

_ Chronic Value

_
Ecotox Values Comments: Predictions are based on SAR-nearest analog method for and indirect effect of algal shading from the ; SAR chemical class = MW 1026/924; p H7; effective concentrations based on 100% active ingredients and mean measured concentrations; hardness <180.0 mg/L as CaCO3; and TOC <2.0 mg/L;

Factors Values Comments

### Assessment Factor 10
Concentration of Concern ( p pb) 30

SARs
SAR Class

Ecotox Factors Comments:

SAT Chair: L Keifer 564-8916

# A-002

Initial Review Engineering Reports

for PMNs P-09-152 and P-09-153

### INITIAL REVIEW ENGINEERING REPORT

P-09-0152 C P-09-0152, P-09-0153 Focus Ready Draft 1/26/2009

ENGINEER: Prothero \ CPW PV (kg/yr):

Revision Notes/Assessment Overview:

SUBMITTER:

USE:

OTHER USES:

MSDS: LABEL :

Gen Eqpt:

Respirator :

Health Effects:
TLV/PEL :

CRSS:
Chemical Name:

Chemical Category : S-H2O: g/L @
VP: torr @
MW: %<500 %<1000 Physical State and Misc CRSS Info:
Neat: Mfg:
Proc/Form: End Use

Consumer Use:

SAT (concerns):

Migration to groundwater : PBT rating:
Health:
Eco:

OCCUPATIONAL EXPOSURE RATING :

NOTES & KEY ASSUMPTIONS :Generated by the 06/07/2005 version of ChemSTEER.

POLLUTION PREVENTION CONSIDERATIONS:
P2 Claim:

P2 REC:

EXPOSURE-BASED REVIEW:P-09-0152 C P-09-0152, P-09-0153P-09-0152 C P-09-0152, P-09-0153

### INITIAL REVIEW ENGINEERING REPORT

P-09-0152 C P-09-0152, P-09-0153 Focus Ready Draft 1/26/2009

ENGINEER: Prothero \ CPW PV (kg/yr):

Revision Notes/Assessment Overview:

SUBMITTER:

USE:

OTHER USES:

MSDS: LABEL :

Gen Eqpt:

Respirator :

Health Effects:
TLV/PEL :

CRSS:
Chemical Name:

Chemical Category : S-H2O: g/L @
VP: torr @
MW: %<500 %<1000 Physical State and Misc CRSS Info:
Neat: Mfg:
Proc/Form: End Use

Consumer Use:

SAT (concerns):

Migration to groundwater : PBT rating:
Health:
Eco:

OCCUPATIONAL EXPOSURE RATING :

NOTES & KEY ASSUMPTIONS :Generated by the 06/07/2005 version of ChemSTEER.

POLLUTION PREVENTION CONSIDERATIONS:
P2 Claim:

P2 REC:

EXPOSURE-BASED REVIEW:P-09-0152 C P-09-0152, P-09-0153P-09-0152 C P-09-0152, P-09-0153

# A-003

Initial Review Exposure Reports

for PMNs P -09- 152 and P -09- 1531/23/09 Page of

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Chemical ID: P090152c Reviewer: Kwon

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air Drinking Water Fish Ingestion

ADR LADD ADR LADD 7Q10
CC=30 PDM Days Exceeded LADD ADR LADD ADR LADD Release activity(ies) 2 ;
exposure calculation(s) 3

mg/kg/day mg/kg/day mg/kg/day mg/kg/day μ g/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day PROC: max ADR, LADD, PDM 1.57E-03 6.75E-06 --- --- 32.22 8 --- --- --- --- ---

USE: max ADR, LADD, PDM 4.14E-02 4.62E-04 --- --- 905.66 184 --- --- --- --- ---

1 Exposure scenario titles consist of release activ ity followed by exposure calculation abbreviation.

2 Release activities are from engineering report's Manufactur ing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location.

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern.

Fate test recommendations: None1/23/09 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090152c Assessor: Kwon

ENVIRONMENTAL RELEASES

Scenario#:1 Number of Release Sites: 1.

Remarks:1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 1 Number of Site s: 1 RELEASE ACTIVITY:PROC: max ADR, LADD, PDM

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 50. 0.25 0.25 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 288.00 123.84 78.18 66.05 0.87 2.02 3.20 3.79

ALL 10 39.60 13.29 7.76 7.57 6.31 18.81 32.22 33.03

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 9.27E-07 6.75E-06 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 4.76E-05 3.46E-04 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.69E-04 1.57E-03 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 1 RELEASE ACTIVI TY: PROC: max ADR, LADD, PDM

SIC CODE RESULTS

COC ( μ g/L) Percent of
Year COC
Exceeded Number of Days COC
Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

30.00 2 8 50.00 0.25 0.00 High1/23/09 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090152c Assessor:

ENVIRONMENTAL RELEASES1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 Number of Sites: 25 RELEASE ACTIVITY:USE: max ADR, LADD, PDM

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 250. 0.96 0.96 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 7.65 21.81 35.82 42.61

ALL 10 11.11 1.94 1.06 0.96 86.41 494.85 905.66 1000.00

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 4.08E-05 4.62E-04 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 2.09E-03 2.37E-02 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.82E-03 4.14E-02 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

Remarks: COC exceeded for > 20 days.1/23/09 Page of



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedence of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure
≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water
≥ 10,000 kg/yr release to environment (post-treatment)
≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences:
≥ 2,000 kg/yr release to environment (post-treatment)
≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.1/23/09 Page of

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air Drinking Water Fish Ingestion

ADR LADD ADR LADD 7Q10
CC=30 PDM Days Exceeded LADD ADR LADD ADR LADD Release activity(ies) 2 ;
exposure calculation(s) 3

mg/kg/day mg/kg/day mg/kg/day mg/kg/day μ g/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day PROC: max ADR, LADD, PDM 1.57E-03 6.75E-06 --- --- 32.22 8 --- --- --- --- ---

USE: max ADR, LADD, PDM 4.14E-02 4.62E-04 --- --- 905.66 184 --- --- --- --- ---

1 Exposure scenario titles consist of release activ ity followed by exposure calculation abbreviation.

2 Release activities are from engineering report's Manufactur ing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location.

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern.

Fate test recommendations: None1/23/09 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090152c Assessor: Kwon1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 1 Number of Site s: 1 RELEASE ACTIVITY:PROC: max ADR, LADD, PDM

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 50. 0.25 0.25 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 288.00 123.84 78.18 66.05 0.87 2.02 3.20 3.79

ALL 10 39.60 13.29 7.76 7.57 6.31 18.81 32.22 33.03

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 9.27E-07 6.75E-06 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 4.76E-05 3.46E-04 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.69E-04 1.57E-03 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

g/site/day) Waste Water Treatment (%) High/Avg Analysis

30.00 2 8 50.00 0.25 0.00 High1/23/09 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P090152c Assessor:1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 250. 0.96 0.96 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 7.65 21.81 35.82 42.61

ALL 10 11.11 1.94 1.06 0.96 86.41 494.85 905.66 1000.00

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 4.08E-05 4.62E-04 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 2.09E-03 2.37E-02 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.82E-03 4.14E-02 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:1/23/09 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P090152c

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SIC CODE RESULTS

COC ( μ g/L) Percent of
Year COC
Exceeded Number of Days COC
Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

30.00 50 184 250.00 0.96 0.00 High

Remarks: COC exceeded for > 20 days.1/23/09 Page of



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedence of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure
≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water
≥ 10,000 kg/yr release to environment (post-treatment)
≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences:
≥ 2,000 kg/yr release to environment (post-treatment)
≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.03/23/2009

POST-FOCUS EXPOSURE REPORT03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152c Assessor:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152c

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C Assessor:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 Number of Sites: 25 RELEASE ACTIVITY:Use: max
PDM

: Adult

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 250. 0.0026 2.60E-03 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 2.07E-02 5.91E-02 9.70E-02 0.12

ALL 10 11.11 1.94 1.06 0.96 0.23 1.34 2.45 2.71

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.11E-07 1.25E-06 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 5.67E-06 6.41E-05 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 4.94E-06 1.12E-04 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 RELEASE ACTIVITY: Use: max PDM

SIC CODE RESULTS

COC ( μ g/L) Percent of
Year COC
Exceeded Number of Days COC
Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

30.00 0 1 250.00 2.60E-03 0.00 High03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C Assessor:

ENVIRONMENTAL RELEASES03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 3 Number of Sites: 25 RELEASE ACTIVITY: Use: max
ADR

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 1. 0.22 0.22 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 1.75 5.00 8.21 9.76

ALL 10 11.11 1.94 1.06 0.96 19.80 113.40 207.55 229.17

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 3.74E-08 4.23E-07 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 1.92E-06 2.17E-05 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 4.18E-04 9.48E-03 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C Assessor:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 4 Number of Sites: 25 RELEASE ACTIVITY: Use: max
LADD

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 1. 0.87 0.87 0.00 0.00

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.48E-07 1.67E-06 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 7.59E-06 8.58E-05 mg/L 0.00 0.00 mg/kg

SIC Code Comments:03/23/2009



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedance of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure
≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water
≥ 10,000 kg/yr release to environment (post-treatment)
≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences:
≥ 2,000 kg/yr release to environment (post-treatment)
≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.03/23/2009

POST-FOCUS EXPOSURE REPORT

Updated according to new engineering report, Post-Foc us Draft Revision 2, 3/23 /2009, to add water releases from processing.

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air

Drinking Water Fish Ingestion

ADR LADD ADR LADD 7Q10
CC=30 PDM Days Exceeded LADD ADR LADD ADR LADD Release activity(ies) 2 ;
exposure calculation(s) 3 m g/kg/day mg/kg/day mg/kg/day mg/kg/day μ g/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day
PROC: max ADR, max LADD, max

acute eco 1.45E05 8.69E-0 9 --- --- 0.30 --- --- --- --- --- ---

USE: max
PDM --- --- --- --- 2.45 1 --- --- --- --- ---

USE: max ADR; max

acute eco 9.48E03 --- --- --- 207.55 --- --- --- --- --- ---

USE: max
LADD --- 1.67E-0 6 --- --- --- --- --- --- --- --- ---

1 Exposure scenario titles consist of release activ ity followed by exposure calculation abbreviation.

2 Release activities are from engineering report's Manufactur ing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location.

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern.

Fate test recommendations: None03/23/2009

POST-FOCUS EXPOSURE REPORT

/

Remarks:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152c

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 7

. 0.0023 2.30E-03 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 288.00 123.84 78.18 66.05 7.99E-03 1.86E-02 2.94E-02 3.48E-02

ALL 10 39.60 13.29 7.76 7.57 5.81E-02 0.17 0.30 0.30

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.19E-09 8.69E-09 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 6.13E-08 4.46E-07 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 1.55E-06 1.45E-05 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C Assessor:

ENVIRONMENTAL RELEASES03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 250. 0.0026 2.60E-03 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 2.07E-02 5.91E-02 9.70E-02 0.12

ALL 10 11.11 1.94 1.06 0.96 0.23 1.34 2.45 2.71

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 1.11E-07 1.25E-06 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 5.67E-06 6.41E-05 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 4.94E-06 1.12E-04 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC CODE EXPOSURES TO SURFACE WATER RELEASES

SIC CODE RESULTS

COC ( μ g/L) Percent of
Year COC
Exceeded Number of Days COC
Exceeded Release days/year Loading (kg/site/day) Waste Water Treatment (%) High/Avg Analysis

30.00 0 1 250.00 2.60E-03 0.00 High03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C Assessor:

Remarks:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

WWT

REMOVAL (%) RELEASE
DAYS PRETREATMENT
RELEASE (kg/site/day) POSTTREATMENT
RELEASE (kg/site/day) DWT
(%) BCF (L/kg)

0.00 1. 0.22 0.22 0.00 0.00

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT
TYPE % ILE
FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic
Mean 30Q5 7Q10 1Q10

ALL 50 125.56 44.02 26.80 22.53 1.75 5.00 8.21 9.76

ALL 10 11.11 1.94 1.06 0.96 19.80 113.40 207.55 229.17

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking
Water Units Fish Ingestion Results Fish Ingestion

Units

50% 10% 50% 10%

Cancer

LADD pot 3.74E-08 4.23E-07 mg/kg/day 0.00 0.00 mg/kg/day

LADC pot 1.92E-06 2.17E-05 mg/L 0.00 0.00 mg/kg

Acute

ADR pot 4.18E-04 9.48E-03 mg/kg/day 0.00 0.00 mg/kg/day

SIC Code Comments:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C Assessor:03/23/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P090152C

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

Comments:03/23/2009



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedance of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure
≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water
≥ 10,000 kg/yr release to environment (post-treatment)
≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences:
≥ 2,000 kg/yr release to environment (post-treatment)
≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.