Exhibit 
21.1

Subsidiaries of Registrant

|Entity                                                    |  | State of
  Incorporation |  | Doing Business As
  (if different from corporate name)         
|--------------------------------------------------------- |  | ------------------------ |  | ---------------------------------------------------------------
|                                                          |  |                          |  |                                                                
|                                                          |  |                          |  |                                                                
|Anniston
  HMA, Inc.                                      |  | Alabama                  |  | Stringfellow
  Memorial Hospital                               
|Bartow HMA,
  Inc.                                        |  | Florida                  |  |                                                                
|Biloxi
  H.M.A., Inc.                                     |  | Mississippi              |  | Biloxi
  Regional Medical Center                               
|Brandon
  H.M.A., Inc.                                    |  | Mississippi              |  | Rankin
  Medical Center                                        
|Canton HMA,
  Inc.                                        |  | Mississippi              |  |                                                                
|Carlisle
  HMA, Inc.                                      |  | Pennsylvania             |  | Carlisle
  Regional Medical Center                             
|Chester HMA,
  Inc.                                       |  | South
  Carolina         |  | Chester
  Regional Medical Center                              
|Chester HMA
  Physician Management, Inc.                  |  | South
  Carolina         |  |                                                                
|Citrus HMA,
  Inc.                                        |  | Florida                  |  | Seven Rivers Regional Medical Center                           
|Clarksdale
  H.M.A., Inc.                                 |  | Mississippi              |  | Northwest
  Mississippi Regional Medical Center                
|Coffee
  Hospital Management
     Associates, Inc. (1)    |  | Tennessee                |  |                                                                
|Collier HMA,
  Inc.                                       |  | Florida                  |  | Collier
  Regional Medical Center                              
|Durant
  H.M.A., Inc.                                     |  | Oklahoma                 |  | Medical
  Center of Southeastern Oklahoma                      
|Durant HMA
  Surgical Center, Inc. (5)                    |  | Oklahoma                 |  |                                                                
|FirstMed,
  Inc.                                          |  | Arkansas                 |  |                                                                
|Gaffney
  H.M.A., Inc.                                    |  | South
  Carolina         |  | Upstate
  Carolina Medical Center                              
|Green
  Clinic, Inc.                                      |  | Florida                  |  |                                                                
|Gulf Coast
  HMA Physician Management, Inc.               |  | Florida                  |  |                                                                
|Haines City
  H.M.A., Inc.                                |  | Florida                  |  | Heart of
  Florida Regional Medical Center                     
|Hamlet
  H.M.A., Inc.                                     |  | North
  Carolina         |  | SandHills
  Regional Medical Center                            
|Hartsville
  H.M.A., Inc.                                 |  | South
  Carolina         |  | Carolina
  Pines Regional Medical Center                       
|Hartsville
  HMA Physician Management, Inc.               |  | South
  Carolina         |  | The Medical
  Group                                            
|Health
  Management Associates of West Virginia, Inc. (1) |  | West
  Virginia          |  | Williamson
  Memorial Hospital                                 
|Health
  Management Associates, Inc.                      |  | Kentucky                 |  |                                                                
|Health
  Management Investments, Inc.                     |  | Delaware                 |  |                                                                
|Hernando
  H.M.A., Inc.                                   |  | Florida                  |  | Brooksville
  Regional Hospital
  Spring Hill Regional Hospital
|HMA Fentress
  County General Hospital, Inc.              |  | Tennessee                |  | Jamestown
  Regional Medical Center                            
|HMA
  Foundation, Inc.                                    |  | Florida                  |  |                                                                
|HMA Mesquite
  Hospital, Inc.                             |  | Texas                    |  | Medical
  Center of Mesquite                                   
|HMA Santa
  Rosa Medical Center, Inc.                     |  | California               |  | Santa Rosa
  Medical Center                                    
|Hospital
  Management Associates, Inc.                    |  | Kentucky                 |  |                                                                
|Insurance
  Company of the Southeast, Ltd.                |  | Cayman
  Islands, BWI    |  |                                                                
|Jackson HMA
  North Medical Office Building,Inc.          |  | Mississippi              |  |                                                                
|Jackson HMA,
  Inc.                                       |  | Mississippi              |  | Central
  Mississippi Medical Center                           
|Kennett HMA,
  Inc.                                       |  | Missouri                 |  | Twin Rivers Regional Medical Center                            
|Kentucky HMA
  Physician Management, Inc.                 |  | Kentucky                 |  |                                                                
|Keystone HMA
  Property Management, Inc.                  |  | Pennsylvania             |  |                                                                
|Key West HMA
  Physician Management, Inc.                 |  | Florida                  |  |                                                                
|Key West
  HMA, Inc.                                      |  | Florida                  |  | Lower Keys
  Medical Center                                    
|Lake Norman
  HMA Surgical Center, Inc.                   |  | North
  Carolina         |  |                                                                
|Lancaster
  HMA, Inc.                                     |  | Pennsylvania             |  | Heart of Lancaster Regional Medical Center                     
|Lancaster
  HMA Physician Management, Inc.                |  | Pennsylvania             |  | Central Penn
  Medical Group                                   

78

---

---

|Entity                                            |  | State of
  Incorporation |  | Doing Business As
  (if different from corporate name)
|------------------------------------------------- |  | ------------------------ |  | ------------------------------------------------------
|                                                  |  |                          |  |                                                       
|                                                  |  |                          |  |                                                       
|Lebanon HMA,
  Inc.                               |  | Tennessee                |  | University Medical Center                             
|Lebanon HMA
  Physician Management Corp.          |  | Tennessee                |  |                                                       
|Lebanon HMA
  Surgery Center, Inc.                |  | Tennessee                |  |                                                       
|Lehigh HMA,
  Inc.                                |  | Florida                  |  | Lehigh
  Regional Medical Center                      
|Little Rock
  H.M.A., Inc.                        |  | Arkansas                 |  | Southwest
  Regional Medical Center                   
|Lone Star
  HMA, L.P.                             |  | Delaware                 |  | Mesquite
  Community Hospital                         
|Louisburg
  H.M.A., Inc.                          |  | North
  Carolina         |  | Franklin
  Regional Medical Center                    
|Madison HMA,
  Inc.                               |  | Mississippi              |  | Madison
  County Medical Center                       
|Marathon
  H.M.A., Inc.                           |  | Florida                  |  | Fishermens
  Hospital                                
|Meridian
  H.M.A. Nursing Home, Inc.              |  | Mississippi              |  |                                                       
|Meridian
  H.M.A., Inc.                           |  | Mississippi              |  | Riley
  Memorial Hospital                             
|Meridian HMA
  Clinic Management, Inc.            |  | Mississippi              |  |                                                       
|Mesquite HMA
  General, LLC                       |  | Delaware                 |  |                                                       
|Mesquite HMA
  Limited, LLC                       |  | Delaware                 |  |                                                       
|Midwest City
  H.M.A., Inc.                       |  | Oklahoma                 |  | Midwest
  Regional Medical Center                     
|Monroe HMA,
  Inc.                                |  | Georgia                  |  | Walton
  Regional Medical Center                      
|Mooresville
  HMA Physician Management,Inc.       |  | North
  Carolina         |  | Primary Care
  Associates                             
|Mooresville
  Hospital Management Associates,Inc. |  | North
  Carolina         |  | Lake Norman
  Regional Medical Center                 
|Natchez
  Community Hospital, Inc.                |  | Mississippi              |  | Natchez
  Community Hospital                          
|Norton HMA,
  Inc.                                |  | Virginia                 |  |                                                       
|Orlando
  H.M.A., Inc.                            |  | Florida                  |  | University
  Behavioral Center                        
|Oviedo, HMA,
  Inc.                               |  | Florida                  |  |                                                       
|Paintsville
  Hospital Company (1)                |  | Kentucky                 |  | Paul B. Hall
  Regional Medical Center                
|Pasco HMA,
  Inc.                                 |  | Florida                  |  | Pasco
  Regional Medical Center                       
|PBEC HMA,
  Inc.                                  |  | Florida                  |  | Pelican Bay
  Executive Center                        
|Pennington
  Gap HMA, Inc.                        |  | Virginia                 |  | Lee Regional
  Medical Center                         
|Personal
  Home Health Care, Inc.(2)              |  | Tennessee                |  |                                                       
|Polk HMA,
  Inc.                                  |  | Florida                  |  |                                                       
|Poplar Bluff
  HMA, Inc.                          |  | Missouri                 |  | Poplar Bluff Regional Medical Center                  
|Poplar Bluff
  HMA Physician ManagementCorp.      |  | Missouri                 |  |                                                       
|Port
  Charlotte HMA, Inc.                        |  | Florida                  |  |                                                       
|Punta Gorda
  HMA, Inc.                           |  | Florida                  |  | Charlotte
  Regional Medical Center                   
|Regional
  Cardiology Center, LLC (3)             |  | Mississippi              |  |                                                       
|River Oaks
  Hospital, Inc                        |  | Mississippi              |  | River Oaks
  Health System                            
|River Oaks
  Management Company (4)               |  | Mississippi              |  | Preferred
  Medical Network                           
|River Oaks
  Medical Office Building, Inc. (4)    |  | Mississippi              |  |                                                       
|Riverview
  Regional Medical Center, Inc.         |  | Alabama                  |  | Riverview
  Regional Medical Center                   
|ROH, Inc.
  (4)                                   |  | Mississippi              |  | Womans
  Hospital at River Oaks                      
|Rose City
  HMA, Inc.                             |  | Pennsylvania             |  | Lancaster
  Regional Medical Center                   
|Sebastian
  Hospital, Inc.                        |  | Florida                  |  | Sebastian
  River Medical Center                      
|Sebring
  Hospital Management Associates, Inc.    |  | Florida                  |  | Highlands
  Regional Medical Center                   
|Statesboro
  H.M.A., Inc.                         |  | Georgia                  |  | East Georgia
  Regional Medical Center                
|Statesville
  HMA, Inc.                           |  | North
  Carolina         |  | Davis
  Regional Medical Center                       
|Tequesta
  H.M.A., Inc.                           |  | Florida                  |  | SandyPines                                            
|The Surgery
  Center at Durant, LLC (6)           |  | Oklahoma                 |  | The Surgery
  Center at Durant                        
|Topeka
  H.M.A., Inc.                             |  | Kansas                   |  |                                                       
|Tullahoma
  HMA, Inc.                             |  | Tennessee                |  | Harton Regional Medical Center                        
|Van Buren
  H.M.A., Inc.                          |  | Arkansas                 |  | Crawford
  Memorial Hospital                          
|Venice HMA,
  Inc.                                |  | Florida                  |  |                                                       
|Yakima HMA,
  Inc                                 |  | Washington               |  | Yakima
  Regional Medical & Heart Center              

79

---

---

|Entity                                  |  | State of
  Incorporation |  | Doing Business As
  (if different from corporate name)
|--------------------------------------- |  | ------------------------ |  | ------------------------------------------------------
|                                        |  |                          |  |                                                       
|                                        |  |                          |  |                                                       
|Yakima HMA
  Physician Management Corp. |  | Washington               |  |                                                       
|                                        |  |                          |  |                                                       

|(1)
  Subsidiary of Health Management Associates, Inc. (Kentucky)
|-----------------------------------------------------------------
|(2)
  Subsidiary of HMA Fentress County General Hospital, Inc.   
|(3)
  Subsidiary of Biloxi H.M.A., Inc.                          
|(4)
  Subsidiary of River Oaks Hospital, Inc.                    
|(5)
  Subsidiary of Durant H.M.A., Inc.                          
|(6)
  Subsidiary of Durant HMA Surgical Center, Inc.             

80

---

---