**Exhibit        32.1**

**CERTIFICATION        PURSUANT TO 18 U.S.C. SECTION 1350, AS ADOPTED**

**PURSUANT        TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002**

| (1) | The                  Report fully complies with the requirements of Section 13(a) or                  15(d) of                  the Securities Exchange Act of 1934;                  and |
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| (2) | The                  information contained in the Report fairly presents, in all material                  respects, the financial condition and results of operations of                  the                  Company. |
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|                            |                                                 |                                                                                                                                                                                                                                                                            |
|---------------------------------|------------------------------------------------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|                            | **IR                    BIOSCIENCES HOLDINGS, INC.** |
|                       |                                            |                                                                                                                                                                                                                                                                       |
| April                  30, 2007 | By:                                        | /s/ Michael                  K.                  Wilhelm                                    |
|                            | Michael                    K. Wilhelm                |
|                            | Chief Executive                  Officer             |

|                            |                                     |                                                                                                                                                                                                                                                                                      |
|---------------------------------|------------------------------------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|                            |                                     |
|                       |                                |                                                                                                                                                                                                                                                                                 |
| April                  30, 2007 | By:                            | /s/ John                  N.                  Fermanis                                      |
|                            | John                    N. Fermanis      |
|                            | Chief Financial                  Officer |

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