**Exhibit 21.1**

Subsidiaries of Registrant

| **Entity**                                                   |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|--------------------------------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                                              |   |                              |   |                                                              |
| Alabama HMA Physician   Management, Inc.                     |   | Alabama                      |   | Cheaha Family Medicine                                       |
|                                                         |   |                         |   | Primary Care Associates                                      |
|                                                         |   |                         |   |                                                         |
| Amory HMA, Inc.                                              |   | Mississippi                  |   | Gilmore Regional Medical   Center                            |
|                                                         |   |                         |   |                                                         |
| Amory HMA Physician   Management Group, Inc.                 |   | Mississippi                  |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Anniston HMA, Inc.                                           |   | Alabama                      |   | Stringfellow Memorial   Hospital                             |
|                                                         |   |                         |   |                                                         |
| Augusta HMA, Inc.                                            |   | Georgia                      |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Bartow HMA, Inc.                                             |   | Florida                      |   | Bartow Regional Medical   Center                             |
|                                                         |   |                         |   |                                                         |
| Biloxi H.M.A., Inc.                                          |   | Mississippi                  |   | Biloxi Regional Medical   Center                             |
|                                                         |   |                         |   |                                                         |
| Biloxi HMA Physician   Management, Inc.                      |   | Mississippi                  |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Brandon HMA, Inc.                                            |   | Mississippi                  |   | Rankin Medical Center                                        |
|                                                         |   |                         |   |                                                         |
| Brooksville HMA Physician   Management, Inc.                 |   | Florida                      |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Canton HMA, Inc.                                             |   | Mississippi                  |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Carlisle HMA, Inc.                                           |   | Pennsylvania                 |   | Carlisle Regional Medical   Center                           |
|                                                         |   |                         |   |                                                         |
| Carlisle HMA Physician   Management, Inc.                    |   | Pennsylvania                 |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Chester        HMA, Inc.                                     |   | South Carolina               |   | Chester Regional Medical   Center                            |
|                                                         |   |                         |   | Chester Nursing Center                                       |
|                                                         |   |                         |   | Neighbors Care Home Health   Agency                          |
|                                                         |   |                         |   | Church Street Clinic                                         |
|                                                         |   |                         |   | Richburg Family Medical   Center                             |
|                                                         |   |                         |   |                                                         |
| Chester HMA Physician   Management, Inc.                     |   | South Carolina               |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Citrus HMA, Inc.                                             |   | Florida                      |   | Seven Rivers Regional   Medical Center                       |
|                                                         |   |                         |   | Seven Rivers Home Care                                       |
|                                                         |   |                         |   | Seven Rivers Rehab Center                                    |
|                                                         |   |                         |   | Seven River Outpatient   Laboratory                          |
|                                                         |   |                         |   | Dunnellon Diagnostic   Center                                |
|                                                         |   |                         |   | Seven Rivers Rehab &   Wound Center                      |
|                                                         |   |                         |   |                                                         |
| Clarksdale HMA, Inc.                                         |   | Mississippi                  |   | Northwest Mississippi   Regional Medical  Center        |
|                                                         |   |                         |   |                                                         |
| Clarksdale HMA Physician   Management, Inc.                  |   | Mississippi                  |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Coffee Hospital Management   Associates, Inc. (1) (inactive) |   | Tennessee                    |   |                                                         |
|                                                         |   |                         |   |                                                         |
| Collier HMA, Inc.                                            |   | Florida                      |   | Collier Regional Medical   Center                            |
|                                                         |   |                         |   |                                                         |
| Durant H.M.A., Inc.                                          |   | Oklahoma                     |   | Medical Center of   Southeastern Oklahoma                    |
|                                                         |   |                         |   | Jaiswal Clinic                                               |
|                                                         |   |                         |   | Southeastern Multispecialty   Group                          |
|                                                         |   |                         |   | Ob/Gyn Associates of SE   Oklahoma                           |
|                                                         |   |                         |   | Donald W. Malone, M.D.   Orthopedic Care                     |
|                                                         |   |                         |   |                                                         |
| Durant HMA Surgical   Center, Inc. (5)                       |   | Oklahoma                     |   |                                                         |

Subsidiaries of Registrant

| **Entity**                                                |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|-----------------------------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                                           |   |                              |   |                                                              |
| FirstMed, Inc.                                            |   | Arkansas                     |   | FirstMed                                                     |
|                                                      |   |                         |   |                                                         |
| Gaffney H.M.A., Inc.                                      |   | South Carolina               |   | Upstate Carolina Medical   Center                            |
|                                                      |   |                         |   |                                                         |
| Gaffney HMA Physician   Management, Inc.                  |   | South Carolina               |   | Gaffney Medical Associates                                   |
|                                                      |   |                         |   |                                                         |
| Georgia HMA Physician   Management, Inc.                  |   | Georgia                      |   |                                                         |
|                                                      |   |                         |   |                                                         |
| Green Clinic, Inc.  (inactive)                       |   | Florida                      |   |                                                         |
|                                                      |   |                         |   |                                                         |
| Gulf Coast HMA Physician   Management, Inc.               |   | Florida                      |   | Gulf Coast Medical Group                                     |
|                                                      |   |                         |   | Charlotte Harbor Cardiac   Surgery Associates                |
|                                                      |   |                         |   | Englewood Primary Care   & Walk-In Clinic                |
|                                                      |   |                         |   | North Port Family Medicine                                   |
|                                                      |   |                         |   | North Port Internal   Medicine                               |
|                                                      |   |                         |   | Port Charlotte Internal   Medicine                           |
|                                                      |   |                         |   | Punta Gorda Cardiology   Group                               |
|                                                      |   |                         |   | Venice Family Medical   & Walk-Ins                       |
|                                                      |   |                         |   | Venice Health Center                                         |
|                                                      |   |                         |   | Venice Hospital Group                                        |
|                                                      |   |                         |   | Venice Internal Medicine   Healthpark                        |
|                                                      |   |                         |   | Venice Internal Medicine   Island                            |
|                                                      |   |                         |   |                                                         |
| Haines City HMA, Inc.                                     |   | Florida                      |   | Heart of Florida Regional   Medical Center                   |
|                                                      |   |                         |   | Heart of Florida Therapy   Center                            |
|                                                      |   |                         |   |                                                         |
| Hamlet H.M.A., Inc.                                       |   | North Carolina               |   | Sandhills Regional Medical   Center                          |
|                                                      |   |                         |   |                                                         |
| Hamlet HMA Physician   Management, Inc.                   |   | North Carolina               |   | Sandhills Medical Group                                      |
|                                                      |   |                         |   |                                                         |
| Hartsville HMA, Inc.                                      |   | South Carolina               |   | Carolina Pines Regional   Medical Center                     |
|                                                      |   |                         |   |                                                         |
| Hartsville HMA Physician   Management, Inc.               |   | South Carolina               |   | The Medical Group                                            |
|                                                      |   |                         |   | Pee Dee Hospitalists                                         |
|                                                      |   |                         |   |                                                         |
| Health Management   Associates of West Virginia, Inc. (1) |   | West Virginia                |   | Williamson Memorial   Hospital                               |
|                                                      |   |                         |   |                                                         |
| Health Management   Associates, Inc.                      |   | Kentucky                     |   |                                                         |
|                                                      |   |                         |   |                                                         |
| Health Management   Investments, Inc.                     |   | Delaware                     |   |                                                         |
|                                                      |   |                         |   |                                                         |
| Hernando HMA, Inc.                                        |   | Florida                      |   | Brooksville Regional   Hospital                              |
|                                                      |   |                         |   | Spring Hill Regional   Hospital                              |
|                                                      |   |                         |   | Special Delivery Suites                                      |
|                                                      |   |                         |   |                                                         |
| HMA Fentress County   General Hospital, Inc.              |   | California                   |   | Jamestown Regional Medical   Center                          |
|                                                      |   |                         |   |                                                         |
| HMA Mesquite Hospital,   Inc.                             |   | Texas                        |   | Medical Center of Mesquite                                   |
|                                                      |   |                         |   |                                                         |
| HMA Santa Rosa Medical   Center, Inc.                     |   | California                   |   | Santa Rosa Medical Center                                    |
|                                                      |   |                         |   | Santa Rosa Medical Group                                     |
|                                                      |   |                         |   | Santa Rosa Primary Care   Center                             |
|                                                      |   |                         |   |                                                         |
| Hospital Management   Associates, Inc.                    |   | Kentucky                     |   |                                                         |

2

Subsidiaries of Registrant

| **Entity**                                        |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|---------------------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                                   |   |                              |   |                                                              |
| Insurance Company of the   Southeast, Ltd.        |   | Cayman Islands, BWI          |   |                                                         |
|                                              |   |                         |   |                                                         |
| Jackson HMA, Inc.                                 |   | Mississippi                  |   | Central Mississippi   Medical Center                         |
|                                              |   |                         |   |                                                         |
| Jackson HMA North Medical   Office Building, Inc. |   | Mississippi                  |   |                                                         |
|                                              |   |                         |   |                                                         |
| Jamestown HMA Physician   Management, Inc.        |   | Tennessee                    |   |                                                         |
|                                              |   |                         |   |                                                         |
| Kennett HMA, Inc.                                 |   | Missouri                     |   | Twin Rivers Regional   Medical Center                        |
|                                              |   |                         |   | Gideon Medical Center                                        |
|                                              |   |                         |   | Senath Medical Center                                        |
|                                              |   |                         |   | Twin Rivers EMS                                              |
|                                              |   |                         |   | Twin Rivers Center for   Women’s Health                 |
|                                              |   |                         |   | Twin Rivers Emergency   Medical Services                     |
|                                              |   |                         |   |                                                         |
| Kentucky HMA Physician Management,   Inc.         |   | Kentucky                     |   | Tug Valley Pediatrics                                        |
|                                              |   |                         |   | Williamson Cardiac Care   Center                             |
|                                              |   |                         |   | Williamson Family Care   Center                              |
|                                              |   |                         |   | Williamson Orthopedic and   Spine Institute                  |
|                                              |   |                         |   |                                                         |
| Key West HMA, Inc.                                |   | Florida                      |   | Lower Keys Medical Center                                    |
|                                              |   |                         |   |                                                         |
| Key West HMA Physician   Management, Inc.         |   | Florida                      |   | South Florida Medical and   Surgical Associates              |
|                                              |   |                         |   | Fishermen’s Hospital   Diagnostic Center                |
|                                              |   |                         |   | Keys Medical Group                                           |
|                                              |   |                         |   | Lower Keys Primary Care   Clinic                             |
|                                              |   |                         |   | Primary Care Center of Key   West                            |
|                                              |   |                         |   | Family Medicine Center of   Marathon                         |
|                                              |   |                         |   | Cardiology Center of   Marathon                              |
|                                              |   |                         |   | Paradise Pulmonary                                           |
|                                              |   |                         |   |                                                         |
| Keystone HMA Property   Management, Inc.          |   | Pennsylvania                 |   |                                                         |
|                                              |   |                         |   |                                                         |
| Lancaster HMA, Inc.                               |   | Pennsylvania                 |   | Heart of Lancaster   Regional Medical Center                 |
|                                              |   |                         |   |                                                         |
| Lancaster HMA Physician   Management, Inc.        |   | Pennsylvania                 |   | Central Penn Medical Group                                   |
|                                              |   |                         |   | Central Penn Management   Group                              |
|                                              |   |                         |   | Heart of Lancaster   Cardiology                              |
|                                              |   |                         |   | Heart of Lancaster   Internal Medicine                       |
|                                              |   |                         |   | Heart of Lancaster Ob Gyn   Clinic                           |
|                                              |   |                         |   | Heart of Lancaster Family   Practice                         |
|                                              |   |                         |   |                                                         |
| Lebanon HMA, Inc.                                 |   | Tennessee                    |   | University Medical Center                                    |
|                                              |   |                         |   | McFarland Specialty   Hospital                               |
|                                              |   |                         |   | University Medical Center   Skilled Nursing Facility         |
|                                              |   |                         |   | Donelson Home Health                                         |
|                                              |   |                         |   |                                                         |
| Lebanon HMA Physician   Management Corp.          |   | Tennessee                    |   | Tennessee Orthopedics and   Sports Medicine                  |
|                                              |   |                         |   | Tennessee Orthopaedics                                       |
|                                              |   |                         |   | Tennessee Medical   Professionals                            |
|                                              |   |                         |   | Reflections                                                  |
|                                              |   |                         |   |                                                         |
| Lebanon HMA Surgery   Center, Inc.                |   | Tennessee                    |   | Lebanon Surgical Center                                      |
|                                              |   |                         |   |                                                         |
| Lehigh HMA, Inc.                                  |   | Florida                      |   | Lehigh Regional Medical   Center                             |
|                                              |   |                         |   | Lehigh Medical Group                                         |
|                                              |   |                         |   | Lehigh Pediatric Care   Center                               |

3

Subsidiaries of Registrant

| **Entity**                                         |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|----------------------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                                    |   |                              |   |                                                              |
| Lehigh HMA Physician   Management, Inc.            |   | Florida                      |   |                                                         |
|                                               |   |                         |   |                                                         |
| Little Rock HMA, Inc.                              |   | Arkansas                     |   | Southwest Regional Medical   Center                          |
|                                               |   |                         |   | First Med Urgent Care                                        |
|                                               |   |                         |   | FirstMed Occupational   Medicine                             |
|                                               |   |                         |   |                                                         |
| Lone Star HMA, L.P.                                |   | Delaware                     |   | Mesquite Community   Hospital                                |
|                                               |   |                         |   |                                                         |
| Louisburg H.M.A., Inc.                             |   | North Carolina               |   | Franklin Regional Medical   Center                           |
|                                               |   |                         |   | Triangle ENT Specialists                                     |
|                                               |   |                         |   |                                                         |
| Louisburg HMA Physician   Management, Inc.         |   | North Carolina               |   |                                                         |
|                                               |   |                         |   |                                                         |
| Madison HMA, Inc.                                  |   | Mississippi                  |   | Madison Regional Medical   Center                            |
|                                               |   |                         |   |                                                         |
| Marathon H.M.A., Inc.                              |   | Florida                      |   | Fishermen’s Hospital                                    |
|                                               |   |                         |   | Big Pine Medical Complex                                     |
|                                               |   |                         |   |                                                         |
| Meridian HMA, Inc.                                 |   | Mississippi                  |   | Riley Hospital                                               |
|                                               |   |                         |   |                                                         |
| Meridian HMA Clinic   Management, Inc.             |   | Mississippi                  |   |                                                         |
|                                               |   |                         |   |                                                         |
| Meridian HMA Nursing Home,   Inc.  (inactive) |   | Mississippi                  |   |                                                         |
|                                               |   |                         |   |                                                         |
| Mesquite HMA General, LLC   (7)                    |   | Delaware                     |   |                                                         |
|                                               |   |                         |   |                                                         |
| Mesquite HMA Limited, LLC   (8)                    |   | Delaware                     |   |                                                         |
|                                               |   |                         |   |                                                         |
| Midwest City H.M.A., Inc.                          |   | Oklahoma                     |   | Midwest Regional Medical   Center                            |
|                                               |   |                         |   |                                                         |
| Monroe HMA, Inc.                                   |   | Georgia                      |   | Walton Regional Medical   Center                             |
|                                               |   |                         |   | Walton Regional Nursing   Home                               |
|                                               |   |                         |   |                                                         |
| Monroe HMA Physician   Management, Inc.            |   | Georgia                      |   |                                                         |
|                                               |   |                         |   |                                                         |
| Mooresville HMA Physician   Management, Inc.       |   | North Carolina               |   | Primary Care Associates                                      |
|                                               |   |                         |   | Primary Care Associates   Internal Medicine                  |
|                                               |   |                         |   | Lakeshore Women’s   Specialists                         |
|                                               |   |                         |   | Lake Norman Neonatology   Associates                         |
|                                               |   |                         |   | Oakhurst Women’s Center at   the Lake                   |
|                                               |   |                         |   | Lake Norman   Center for Digestive & Liver Disease       |
|                                               |   |                         |   | Center for Infectious   Disease                              |
|                                               |   |                         |   | North Mecklenburg Medical   Associates                       |
|                                               |   |                         |   |                                                         |
| Mooresville Hospital Management   Associates, Inc. |   | North Carolina               |   | Hospitalists of Lake   Norman                                |
|                                               |   |                         |   | The Surgical Center at   Lake Norman                         |
|                                               |   |                         |   | Lake Norman Regional   Medical Center                        |
|                                               |   |                         |   |                                                         |
| Natchez Community   Hospital, Inc.                 |   | Mississippi                  |   | Natchez Community Hospital                                   |
|                                               |   |                         |   |                                                         |
| Natchez HMA Physician   Management, Inc.           |   | Mississippi                  |   |                                                         |
|                                               |   |                         |   |                                                         |
| North Port HMA, Inc.                               |   | Florida                      |   |                                                         |
|                                               |   |                         |   |                                                         |
| Norton HMA, Inc.                                   |   | Virginia                     |   | Mountain View Regional   Medical Center                      |
|                                               |   |                         |   |                                                         |
| Orlando H.M.A., Inc.                               |   | Florida                      |   | University Behavioral   Center                               |
|                                               |   |                         |   |                                                         |
| OsceolaSC, LLC                                     |   | Delaware                     |   | St. Cloud Regional Medical   Center                          |
|                                               |   |                         |   |                                                         |
| Oviedo HMA, Inc.                                   |   | Florida                      |   |                                                         |

4

Subsidiaries of Registrant

| **Entity**                                      |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|-------------------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                                 |   |                              |   |                                                              |
| Paintsville HMA Physician   Management, Inc.    |   | Kentucky                     |   |                                                         |
|                                            |   |                         |   |                                                         |
| Paintsville Hospital   Company (1)              |   | Kentucky                     |   | Paul B. Hall Regional   Medical Center                       |
|                                            |   |                         |   | Women’s Center of   Paintsville                         |
|                                            |   |                         |   |                                                         |
| Pasco Hernando HMA   Physician Management, Inc. |   | Florida                      |   | East Pasco Family Medicine                                   |
|                                            |   |                         |   | East Pasco Family Practice                                   |
|                                            |   |                         |   | East Pasco Primary Care                                      |
|                                            |   |                         |   | Pasco Orthopaedic Clinic                                     |
|                                            |   |                         |   | Pasco Regional Anesthesia                                    |
|                                            |   |                         |   |                                                         |
| Pasco HMA, Inc.                                 |   | Florida                      |   | Pasco Regional Medical   Center                              |
|                                            |   |                         |   | Pasco Medical Plaza   Condominium                            |
|                                            |   |                         |   |                                                         |
| PBEC HMA, Inc.                                  |   | Florida                      |   | Pelican Bay Executive   Center                               |
|                                            |   |                         |   |                                                         |
| Peace River HMA Nursing   Center, Inc.          |   | Florida                      |   | Peace River Nursing and   Rehabilitation Center              |
|                                            |   |                         |   |                                                         |
| Pennington Gap HMA, Inc.                        |   | Virginia                     |   | Lee Regional Medical   Center                                |
|                                            |   |                         |   |                                                         |
| Personal Home Health Care,   Inc. (2)           |   | Tennessee                    |   |                                                         |
|                                            |   |                         |   |                                                         |
| Polk HMA, Inc.                                  |   | Florida                      |   |                                                         |
|                                            |   |                         |   |                                                         |
| Poplar Bluff Regional   Medical Center, Inc.    |   | Missouri                     |   | Poplar Bluff Regional   Medical Center-North                 |
|                                            |   |                         |   | Poplar Bluff Regional   Medical Center-South                 |
|                                            |   |                         |   | Piedmont Family Pharmacy                                     |
|                                            |   |                         |   | Three Rivers Lab and X-ray                                   |
|                                            |   |                         |   | Three Rivers Healthcare   Home Health                        |
|                                            |   |                         |   | Three Rivers Healthcare   Pathology Services                 |
|                                            |   |                         |   | Three Rivers Healthcare   Hospice                            |
|                                            |   |                         |   |                                                         |
| Poplar Bluff HMA Physician   Management, Inc.   |   | Missouri                     |   | Piedmont Family Clinic                                       |
|                                            |   |                         |   | Malden Medical Center                                        |
|                                            |   |                         |   | Puxico Medical Center                                        |
|                                            |   |                         |   | Dexter Medical Center                                        |
|                                            |   |                         |   | Bloomfield Medical Clinic                                    |
|                                            |   |                         |   | Ozark Hospitalist Group                                      |
|                                            |   |                         |   | Ozark Medical Management                                     |
|                                            |   |                         |   | Ozark Heart & Vascular   Institute                       |
|                                            |   |                         |   |                                                         |
| Port Charlotte HMA, Inc.                        |   | Florida                      |   | Peace River Regional   Medical Center                        |
|                                            |   |                         |   | Peace River Home Health   Services                           |
|                                            |   |                         |   |                                                         |
| Punta Gorda HMA, Inc.                           |   | Florida                      |   | Charlotte Regional Medical   Center                          |
|                                            |   |                         |   | Riverside Behavioral   Center                                |
|                                            |   |                         |   | Wound Care Clinic of Charlotte                               |
|                                            |   |                         |   | North Port Family Health   Center                            |
|                                            |   |                         |   | Home Health Services of   Charlotte                          |
|                                            |   |                         |   | Charlotte Regional Private   Duty Services                   |
|                                            |   |                         |   |                                                         |
| Regional Cardiology Center   LLC (3)            |   | Mississippi                  |   |                                                         |
|                                            |   |                         |   |                                                         |
| River Oaks Hospital, Inc.                       |   | Mississippi                  |   | River Oaks Health System                                     |
|                                            |   |                         |   | River Oaks Hospital                                          |
|                                            |   |                         |   |                                                         |
| River Oaks Management   Company, Inc. (4)       |   | Mississippi                  |   | Preferred Medical Network                                    |

5

Subsidiaries of Registrant

| **Entity**                                        |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|---------------------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                                   |   |                              |   |                                                              |
| River Oaks Medical Office   Building, Inc. (4)    |   | Mississippi                  |   |                                                         |
|                                              |   |                         |   |                                                         |
| Riverview Regional Medical   Center, Inc.         |   | Alabama                      |   | Riverview Regional Medical   Center                          |
|                                              |   |                         |   |                                                         |
| ROH, Inc. (4)                                     |   | Mississippi                  |   | Woman’s Hospital at River   Oaks                        |
|                                              |   |                         |   |                                                         |
| Rose City HMA, Inc.                               |   | Pennsylvania                 |   | Lancaster Regional Medical   Center                          |
|                                              |   |                         |   |                                                         |
| Santa Rosa HMA Physician   Management, Inc.       |   | Florida                      |   |                                                         |
|                                              |   |                         |   |                                                         |
| Sebastian Hospital, Inc.                          |   | Florida                      |   | Sebastian River Medical   Center                             |
|                                              |   |                         |   | Sebastian River Home   Health                                |
|                                              |   |                         |   |                                                         |
| Sebring HMA Physician   Management, Inc.          |   | Florida                      |   |                                                         |
|                                              |   |                         |   |                                                         |
| Sebring Hospital   Management Associates, Inc.    |   | Florida                      |   | Highlands Regional Medical   Center                          |
|                                              |   |                         |   | Highland Medical Group                                       |
|                                              |   |                         |   |                                                         |
| St. Cloud HMA Physician   Management, Inc.        |   | Florida                      |   |                                                         |
|                                              |   |                         |   |                                                         |
| Statesboro HMA, Inc.                              |   | Georgia                      |   | East Georgia Regional   Medical Center                       |
|                                              |   |                         |   |                                                         |
| Statesboro HMA Physician   Management, Inc.       |   | Georgia                      |   |                                                         |
|                                              |   |                         |   |                                                         |
| Statesville HMA, Inc.                             |   | North Carolina               |   | Davis Regional Medical   Center                              |
|                                              |   |                         |   |                                                         |
| Tequesta HMA, Inc.                                |   | Florida                      |   | SandyPines                                                   |
|                                              |   |                         |   |                                                         |
| The Surgery Center at   Durant, LLC (6)           |   | Oklahoma                     |   | The Surgery Center at   Durant                               |
|                                              |   |                         |   |                                                         |
| Topeka H.M.A., Inc.  (inactive)              |   | Kansas                       |   |                                                         |
|                                              |   |                         |   |                                                         |
| Tullahoma HMA, Inc.                               |   | Tennessee                    |   | Harton Regional Medical   Center                             |
|                                              |   |                         |   | Family Medical Center                                        |
|                                              |   |                         |   | Family Medical Center of   Decherd                           |
|                                              |   |                         |   | Medical Home Health Care                                     |
|                                              |   |                         |   |                                                         |
| Tullahoma HMA Physician   Management, Inc.        |   | Tennessee                    |   |                                                         |
|                                              |   |                         |   |                                                         |
| Van Buren H.M.A., Inc.                            |   | Arkansas                     |   | Summit Medical Center                                        |
|                                              |   |                         |   | Complete Knee Center of   Arkansas                           |
|                                              |   |                         |   | Cornerstone Family Clinic                                    |
|                                              |   |                         |   | Cornerstone Medical Group                                    |
|                                              |   |                         |   | Southwest Impotency Clinic                                   |
|                                              |   |                         |   |                                                         |
| Venice HMA, Inc.                                  |   | Florida                      |   | Venice Regional Medical   Center                             |
|                                              |   |                         |   | Home Health Services of   Venice                             |
|                                              |   |                         |   | Personal Care Services                                       |
|                                              |   |                         |   | Regional Oxygen & Medical   Equipment                    |
|                                              |   |                         |   |                                                         |
| Western Virginia HMA   Physician Management, Inc. |   | Virginia                     |   | Dickenson Clinic                                             |
|                                              |   |                         |   | Health Associates                                            |
|                                              |   |                         |   | OB\GYN Clinic                                                |
|                                              |   |                         |   | Orthopedic Center                                            |
|                                              |   |                         |   | Pediatric Center                                             |
|                                              |   |                         |   | Wise Medical Group                                           |
|                                              |   |                         |   |                                                         |
| Winder HMA, Inc.                                  |   | Georgia                      |   | Barrow Regional Medical Center                               |

6

Subsidiaries of Registrant

| **Entity**                              |   | **State of   Incorporation** |   | **Doing   Business As   (If different from corporate name)** |
|-----------------------------------------|--------|------------------------------|--------|--------------------------------------------------------------|
|                                         |   |                              |   |                                                              |
| Yakima HMA, Inc.                        |   | Washington                   |   | Yakima Regional Medical   & Heart Center                 |
|                                    |   |                         |   | Yakima Regional Medical   and Cardiac Center                 |
|                                    |   |                         |   | Yakima Regional Home   Health & Hospice                  |
|                                    |   |                         |   | Yakima Regional Medical   Center Pharmacy                    |
|                                    |   |                         |   | Toppenish Regional Medical                                   |
|                                    |   |                         |   | Toppenish Regional Medical   Center Pharmacy                 |
|                                    |   |                         |   | Toppenish Community   Hospital                               |
|                                    |   |                         |   |                                                         |
| Yakima HMA Physician   Management Corp. |   | Washington                   |   | Central Washington   Occupational Medicine                   |
|                                    |   |                         |   | Terrace Heights Family   Physicians                          |
|                                    |   |                         |   | Midvalley Family Medicine                                    |
|                                    |   |                         |   | Central Washington   Neurosciences                           |
|                                    |   |                         |   | Central Washington   Endocrine Center                        |
|                                    |   |                         |   | Central Washington   Rehabilitation                          |
|                                    |   |                         |   | Emergency Physicians   Toppenish                             |
|                                    |   |                         |   | YRMC Cardiology                                              |
|                                    |   |                         |   | YRMC Anesthesiology                                          |
|                                    |   |                         |   | Toppenish Anesthesiology                                     |