Exhibit 21.1

Subsidiaries of
Registrant

|                                            |  | State of      |  | Doing Business
    As                        
|------------------------------------------- |  | ------------- |  | ---------------------------------------------
|Entity                                      |  | Incorporation |  | (If different from corporate name)           
|Alabama HMA Physician Management, Inc.      |  | Alabama       |  | Cheaha Family Medicine                       
|                                            |  |               |  | Primary Care Associates                      
|                                            |  |               |  |                                              
|Amory HMA, Inc.                             |  | Mississippi   |  | Gilmore Regional Medical Center              
|                                            |  |               |  |                                              
|Amory HMA Physician Management Group, Inc.  |  | Mississippi   |  |                                              
|                                            |  |               |  |                                              
|Anniston HMA, Inc.                          |  | Alabama       |  | Stringfellow Memorial Hospital               
|                                            |  |               |  |                                              
|Augusta HMA, Inc.                           |  | Georgia       |  |                                              
|                                            |  |               |  |                                              
|Augusta HMA Physician Management, Inc.      |  | Georgia       |  |                                              
|                                            |  |               |  |                                              
|Bartow HMA, Inc.                            |  | Florida       |  | Bartow Regional Medical Center               
|                                            |  |               |  |                                              
|Bartow HMA Physician Management, Inc.       |  | Florida       |  | Womens Health Specialists of Central Florida
|                                            |  |               |  |                                              
|Biloxi H.M.A., Inc.                         |  | Mississippi   |  | Biloxi Regional Medical Center               
|                                            |  |               |  |                                              
|Biloxi HMA Physician Management, Inc.       |  | Mississippi   |  | Center for Industrial Health & Wellness      
|                                            |  |               |  | Lakeview Family Medicine Center              
|                                            |  |               |  |                                              
|Brandon HMA, Inc.                           |  | Mississippi   |  | Rankin Medical Center                        
|                                            |  |               |  |                                              
|Brooksville HMA Physician Management, Inc.  |  | Florida       |  |                                              
|                                            |  |               |  |                                              
|Canton HMA, Inc.                            |  | Mississippi   |  |                                              
|                                            |  |               |  |                                              
|Carlisle HMA, Inc.                          |  | Pennsylvania  |  | Carlisle Regional Medical Center             
|                                            |  |               |  | Carlisle Regional Surgery Center             
|                                            |  |               |  |                                              
|Carlisle HMA Physician Management, Inc.     |  | Pennsylvania  |  |                                              
|                                            |  |               |  |                                              
|Chester HMA, Inc.                           |  | South         |  | Chester Regional Medical Center              
|                                            |  | Carolina      |  | Chester Nursing Center                       
|                                            |  |               |  | Neighbors Care Home Health Agency            
|                                            |  |               |  | Church Street Clinic                         
|                                            |  |               |  | Richburg Family Medical Center               
|                                            |  |               |  |                                              
|Chester HMA Physician Management, Inc.      |  | South         |  |                                              
|                                            |  | Carolina      |  |                                              
|                                            |  |               |  |                                              
|Citrus HMA, Inc.                            |  | Florida       |  | Seven Rivers Regional Medical Center         
|                                            |  |               |  | Seven Rivers Home Care                       
|                                            |  |               |  | Seven Rivers Rehab Center                    
|                                            |  |               |  | Seven River Outpatient Laboratory            
|                                            |  |               |  | Dunnellon Diagnostic Center                  
|                                            |  |               |  | Seven Rivers Rehab & Wound Center            
|                                            |  |               |  |                                              
|Clarksdale HMA, Inc.                        |  | Mississippi   |  | Northwest Mississippi Regional Medical Center
|                                            |  |               |  |                                              
|Clarksdale HMA Physician Management, Inc.   |  | Mississippi   |  |                                              
|                                            |  |               |  |                                              
|Coffee Hospital Management Associates, Inc. |  | Tennessee     |  |                                              
|(1) (inactive)                              |  |               |  |                                              
|                                            |  |               |  |                                              
|Collier HMA Facility Based Physician        |  | Florida       |  |                                              
|Management, Inc.                            |  |               |  |                                              
|                                            |  |               |  |                                              
|Collier HMA Physician Management, Inc.      |  | Florida       |  | Medical Surgical Specialists                 
|                                            |  |               |  | Naples Medical & Surgical Specialists        

1

---

Subsidiaries of
Registrant

|                                             |  | State of      |  | Doing Business
    As                      
|-------------------------------------------- |  | ------------- |  | -------------------------------------------
|Entity                                       |  | Incorporation |  | (If different from corporate name)         
|Crystal River HMA Physician Management, Inc. |  | Florida       |  |                                            
|                                            
|Durant H.M.A., Inc.                          |  | Oklahoma      |  | Medical Center of Southeastern Oklahoma    
|                                             |  |               |  | Jaiswal Clinic                             
|                                             |  |               |  | Southeastern Multispecialty Group          
|                                             |  |               |  | Ob/Gyn Associates of SE Oklahoma           
|                                             |  |               |  | Donald W. Malone, M.D. Orthopedic Care     
|                                            
|Durant HMA Surgical Center, Inc. (5)         |  | Oklahoma      |  | The Surgery Center at Durant               
|                                            
|Durant HMA Physician Management, Inc.        |  | Oklahoma      |  |                                            
|                                            
|FirstMed, Inc.                               |  | Arkansas      |  |                                            
|                                             |  |               |  |                                            
|Florida HMA Urgent Care, Inc.                |  | Florida       |  |                                            
|                                             |  |               |  |                                            
|Gadsden HMA Physician Management, Inc.       |  | Alabama       |  |                                            
|                                             |  |               |  |                                            
|Gaffney H.M.A., Inc.                         |  | South         |  | Upstate Carolina Medical Center            
|                                             |  | Carolina      |  |                                            
|                                             |  |               |  |                                            
|Gaffney HMA Physician Management, Inc.       |  | South         |  | Gaffney Medical Associates                 
|                                             |  | Carolina      |  |                                            
|                                             |  |               |  |                                            
|Georgia HMA Physician Management, Inc.       |  | Georgia       |  | The Childrens Group                       
|                                             |  |               |  |                                            
|Green Clinic, Inc. (inactive)                |  | Florida       |  |                                            
|                                             |  |               |  |                                            
|Gulf Coast HMA Physician Management, Inc.    |  | Florida       |  | Gulf Coast Medical Group                   
|                                             |  |               |  | Charlotte Harbor Cardiac Surgery Associates
|                                             |  |               |  | Englewood Primary Care & Walk-In Clinic    
|                                             |  |               |  | North Port Family Medicine                 
|                                             |  |               |  | North Port Internal Medicine               
|                                             |  |               |  | Port Charlotte Internal Medicine           
|                                             |  |               |  | Punta Gorda Cardiology Group               
|                                             |  |               |  | Venice Family Medical & Walk-Ins           
|                                             |  |               |  | Venice Health Center                       
|                                             |  |               |  | Venice Hospital Group                      
|                                             |  |               |  | Venice Internal Medicine Healthpark        
|                                             |  |               |  | Venice Internal Medicine Island            
|                                             |  |               |  |                                            
|Haines City HMA, Inc.                        |  | Florida       |  | Heart of Florida Regional Medical Center   
|                                             |  |               |  | Center for Healthy Workforce               
|                                             |  |               |  | Heart of Florida Therapy Center            
|                                             |  |               |  |                                            
|Hamlet H.M.A., Inc.                          |  | North         |  | Sandhills Regional Medical Center          
|                                             |  | Carolina      |  |                                            
|                                             |  |               |  |                                            
|Hamlet HMA Physician Management, Inc.        |  | North         |  | Sandhills Medical Group                    
|                                             |  | Carolina      |  |                                            
|                                             |  |               |  |                                            
|Harrison HMA, Inc.                           |  | Mississippi   |  | Gulf Coast Medical Center                  
|                                             |  |               |  |                                            
|Harrison HMA Physician Management, Inc.      |  | Mississippi   |  |                                            
|                                             |  |               |  |                                            
|Hartsville HMA, Inc.                         |  | South         |  | Carolina Pines Regional Medical Center     
|                                             |  | Carolina      |  |                                            

2

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Subsidiaries of
Registrant

|                                                      |  | State of      |  | Doing Business
    As                        
|----------------------------------------------------- |  | ------------- |  | ---------------------------------------------
|Entity                                                |  | Incorporation |  | (If different from corporate name)           
|Hartsville HMA Physician Management, Inc.             |  | South         |  | The Medical Group                            
|                                                      |  | Carolina      |  | Pee Dee Hospitalists                         
|                                                      |  |               |  | The Children's Group                         
|                                                      |  |               |  | Children's Care Clinic                       
|                                                      |  |               |  |                                              
|Health Management Associates of West                  |  | West Virginia |  | Williamson Memorial Hospital                 
|Virginia, Inc. (1)                                    |  |               |  |                                              
|                                                      |  |               |  |                                              
|Health Management Associates, Inc.                    |  | Kentucky      |  |                                              
|                                                      |  |               |  |                                              
|Hernando HMA, Inc.                                    |  | Florida       |  | Hernando Healthcare                          
|                                                      |  |               |  | Brooksville Regional Hospital                
|                                                      |  |               |  | Spring Hill Regional Hospital                
|                                                      |  |               |  | Special Delivery Suites                      
|                                                      |  |               |  |                                              
|HMA Fentress County General Hospital, Inc.            |  | California    |  | Jamestown Regional Medical Center            
|                                                      |  |               |  |                                              
|HMA Mesquite Hospital, Inc.                           |  | Texas         |  | Medical Center of Mesquite                   
|                                                      |  |               |  |                                              
|HMA Physician Practice Management, Inc.               |  | Florida       |  |                                              
|                                                      |  |               |  |                                              
|HMA Santa Rosa Medical Center, Inc.                   |  | California    |  | Santa Rosa Medical Center                    
|                                                      |  |               |  | Santa Rosa Medical Group                     
|                                                      |  |               |  | Santa Rosa Primary Care Center               
|                                                      |  |               |  |                                              
|Hospital Management Associates, Inc.                  |  | Kentucky      |  |                                              
|                                                      |  |               |  |                                              
|Hospital Management Services of Florida, Inc.         |  | Kentucky      |  |                                              
|                                                      |  |               |  |                                              
|Insurance Company of the Southeast, Ltd.              |  | Cayman        |  |                                              
|                                                      |  | Islands, BWI  |  |                                              
|                                                      |  |               |  |                                              
|Jackson HMA, Inc.                                     |  | Mississippi   |  | Central Mississippi Medical Center           
|                                                      |  |               |  |                                              
|Jackson HMA North Medical Office Building,
      Inc. |  | Mississippi   |  |                                              
|                                                      |  |               |  |                                              
|Jamestown HMA Physician Management, Inc.              |  | Tennessee     |  |                                              
|                                                      |  |               |  |                                              
|Kennett HMA, Inc.                                     |  | Missouri      |  | Twin Rivers Regional Medical Center          
|                                                      |  |               |  |                                              
|Kennett HMA Physician Management, Inc.                |  | Missouri      |  |                                              
|                                                      |  |               |  |                                              
|Kentucky HMA Physician Management, Inc.               |  | Kentucky      |  | Tug Valley Pediatrics                        
|                                                      |  |               |  | Williamson Cardiac Care Center               
|                                                      |  |               |  | Williamson Family Care Center                
|                                                      |  |               |  |                                              
|Key West HMA, Inc.                                    |  | Florida       |  | Lower Keys Medical Center                    
|                                                      |  |               |  |                                              
|Key West HMA Physician Management, Inc.               |  | Florida       |  | South Florida Medical and Surgical Associates
|                                                      |  |               |  | Fishermen's Hospital Diagnostic Center       
|                                                      |  |               |  | Keys Medical Group                           
|                                                      |  |               |  | Lower Keys Primary Care Clinic               
|                                                      |  |               |  | Primary Care Center of Key West              
|                                                      |  |               |  | Family Medicine Center of Marathon           
|                                                      |  |               |  | Cardiology Center of Marathon                
|                                                      |  |               |  | Paradise Pulmonary                           
|                                                      |  |               |  |                                              
|Keystone HMA Property Management, Inc.                |  | Pennsylvania  |  |                                              
|                                                      |  |               |  |                                              
|Lancaster HMA, Inc.                                   |  | Pennsylvania  |  | Heart of Lancaster Regional Medical Center   

3

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Subsidiaries of
Registrant

|                                           |  | State of      |  | Doing Business
    As                             
|------------------------------------------ |  | ------------- |  | --------------------------------------------------
|Entity                                     |  | Incorporation |  | (If different from corporate name)                
|Lancaster HMA Physician Management, Inc.   |  | Pennsylvania  |  | Central Penn Medical Group                        
|                                           |  |               |  | Central Penn Management Group                     
|                                           |  |               |  | Heart of Lancaster Cardiology                     
|                                           |  |               |  | Heart of Lancaster Internal Medicine              
|                                           |  |               |  | Heart of Lancaster Ob Gyn Clinic                  
|                                           |  |               |  | Heart of Lancaster Family Practice                
|                                           |  |               |  | Highlands Family Practice                         
|                                           |  |               |  | Carlisle Urology                                  
|                                           |  |               |  | Cardiothoracic & Vascular Surgeons of Lancaster   
|                                           |  |               |  |                                                   
|Lebanon HMA, Inc.                          |  | Tennessee     |  | University Medical Center                         
|                                           |  |               |  | McFarland Specialty Hospital                      
|                                           |  |               |  | University Medical Center Skilled Nursing Facility
|                                           |  |               |  | Donelson Home Health                              
|                                           |  |               |  |                                                   
|Lebanon HMA Physician Management Corp.     |  | Tennessee     |  | Tennessee Orthopedics and Sports Medicine         
|                                           |  |               |  | Tennessee Orthopaedics                            
|                                           |  |               |  | Tennessee Medical Professionals                   
|                                           |  |               |  | Reflections                                       
|                                           |  |               |  | Women's Wellness of Lebanon                       
|                                           |  |               |  |                                                   
|Lebanon HMA Surgery Center, Inc.           |  | Tennessee     |  | Lebanon Surgical Center                           
|                                           |  |               |  |                                                   
|Lehigh HMA, Inc.                           |  | Florida       |  | Lehigh Regional Medical Center                    
|                                           |  |               |  | Lehigh Pediatric Care Center                      
|                                           |  |               |  |                                                   
|Lehigh HMA Physician Management, Inc.      |  | Florida       |  | Lehigh Medical Group                              
|                                           |  |               |  |                                                   
|Little Rock HMA, Inc.                      |  | Arkansas      |  | Southwest Regional Medical Center                 
|                                           |  |               |  | First Med Urgent Care                             
|                                           |  |               |  | FirstMed Occupational Medicine                    
|                                           |  |               |  |                                                   
|Lone Star HMA, L.P.                        |  | Delaware      |  | Mesquite Community Hospital                       
|                                           |  |               |  |                                                   
|Louisburg H.M.A., Inc.                     |  | North         |  | Franklin Regional Medical Center                  
|                                           |  | Carolina      |  |                                                   
|                                           |  |               |  |                                                   
|Louisburg HMA Physician Management, Inc.   |  | North         |  | Perry Medders Medical Group                       
|                                           |  | Carolina      |  | Franklin Pediatric Care                           
|                                           |  |               |  | Triangle ENT Specialists                          
|                                           |  |               |  | Franklin Family Medicine                          
|                                           |  |               |  | Franklinton Medical Practice                      
|                                           |  |               |  | Heritage Family Care                              
|                                           |  |               |  |                                                   
|Madison HMA, Inc.                          |  | Mississippi   |  | Madison Regional Medical Center                   
|                                           |  |               |  |                                                   
|Madison HMA Physician Management, Inc.     |  | Mississippi   |  |                                                   
|                                           |  |               |  |                                                   
|Marathon H.M.A., Inc.                      |  | Florida       |  | Fishermen's Hospital                              
|                                           |  |               |  | Big Pine Medical Complex                          
|                                           |  |               |  |                                                   
|Meridian HMA, Inc.                         |  | Mississippi   |  | Riley Hospital                                    
|                                           |  |               |  |                                                   
|Meridian HMA Clinic Management, Inc.       |  | Mississippi   |  |                                                   
|                                           |  |               |  |                                                   
|Meridian HMA Nursing Home, Inc. (inactive) |  | Mississippi   |  |                                                   
|                                           |  |               |  |                                                   
|Mesquite HMA General, LLC (7)              |  | Delaware      |  |                                                   
|                                           |  |               |  |                                                   
|Mesquite HMA Limited, LLC (8)              |  | Delaware      |  |                                                   

4

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Subsidiaries of
Registrant

|                                                 |  | State of      |  | Doing Business
    As                           
|------------------------------------------------ |  | ------------- |  | ------------------------------------------------
|Entity                                           |  | Incorporation |  | (If different from corporate name)              
|Midwest City H.M.A., Inc.                        |  | Oklahoma      |  | Midwest Regional Medical Center                 
|                                                
|Midwest City HMA Physician Management, Inc.      |  | Oklahoma      |  |                                                 
|                                                
|Monroe HMA, Inc.                                 |  | Georgia       |  | Walton Regional Medical Center                  
|                                                 |  |               |  | Walton Regional Nursing Home                    
|                                                
|Monroe HMA Physician Management, Inc.            |  | Georgia       |  | Social Circle Family Medicine                   
|                                                 |  |               |  | Walton OB/GYN Specialists                       
|                                                 |  |               |  | Walton Pulmonary and Sleep Medicine             
|                                                 |  |               |  | Walton Surgical Group                           
|                                                 |  |               |  | Barrow Surgical Associates                      
|                                                 |  |               |  | Winder Pediatrics                               
|                                                 |  |               |  |                                                 
|Mooresville HMA Physician Management, Inc.       |  | North         |  | Primary Care Associates                         
|                                                 |  | Carolina      |  | Primary Care Associates Internal Medicine       
|                                                 |  |               |  | Lakeshore Women's Specialists                   
|                                                 |  |               |  | Lake Norman Neonatology Associates              
|                                                 |  |               |  | Oakhurst Women's Center at the Lake             
|                                                 |  |               |  | Lake Norman Center for Digestive & Liver Disease
|                                                 |  |               |  | Center for Infectious Disease                   
|                                                 |  |               |  | North Mecklenburg Medical Associates            
|                                                 |  |               |  | Sherrill Orthopaedics                           
|                                                
|Mooresville Hospital Management Associates, Inc. |  | North         |  | Lake Norman Regional Medical Center             
|                                                 |  | Carolina      |  | Hospitalists of Lake Norman                     
|                                                 |  |               |  | The Surgical Center at Lake Norman              
|                                                 |  |               |  | Davis Regional Home Health                      
|                                                 |  |               |  |                                                 
|Naples HMA, Inc.                                 |  | Florida       |  | Physicians Regional Healthcare System           
|                                                 |  |               |  | Physicians Regional Medical Center-Pine Ridge   
|                                                 |  |               |  | Physicians Regional Medical Center-Collier      
|                                                 |  |               |  | Boulevard                                       
|                                                
|Natchez Community Hospital, Inc.                 |  | Mississippi   |  | Natchez Community Hospital                      
|                                                
|Natchez HMA Physician Management, Inc.           |  | Mississippi   |  | Family Medical Center                           
|                                                
|North Port HMA, Inc.                             |  | Florida       |  |                                                 
|                                                
|Norton HMA, Inc.                                 |  | Virginia      |  | Mountain View Regional Medical Center           
|                                                
|Orlando H.M.A., Inc.                             |  | Florida       |  |                                                 
|                                                
|OsceolaSC, LLC                                   |  | Delaware      |  | St. Cloud Regional Medical Center               
|                                                
|Oviedo HMA, Inc.                                 |  | Florida       |  |                                                 
|                                                
|Paintsville HMA Physician Management, Inc.       |  | Kentucky      |  |                                                 
|                                                
|Paintsville Hospital Company (1)                 |  | Kentucky      |  | Paul B. Hall Regional Medical Center            
|                                                 |  |               |  | Women's Center of Paintsville                   

5

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Subsidiaries of
Registrant

|                                              |  | State of      |  | Doing Business
    As                        
|--------------------------------------------- |  | ------------- |  | ---------------------------------------------
|Entity                                        |  | Incorporation |  | (If different from corporate name)           
|Pasco Hernando HMA Physician Management, Inc. |  | Florida       |  | A Place for Women of Pasco County            
|                                              |  |               |  | East Pasco Family Medicine                   
|                                              |  |               |  | East Pasco Family Practice                   
|                                              |  |               |  | East Pasco Primary Care                      
|                                              |  |               |  | Lake Jovita Family Practice                  
|                                              |  |               |  | Lake Jovita Internal Medicine                
|                                              |  |               |  | Lake Jovita Primary Care                     
|                                              |  |               |  | Pasco Orthopaedic Clinic                     
|                                              |  |               |  | Pasco Regional Anesthesia                    
|                                              |  |               |  | Place for Women                              
|                                              |  |               |  | The Place for Women                          
|                                              |  |               |  | Women's Health of Pasco                      
|                                              |  |               |  |                                              
|Pasco HMA, Inc.                               |  | Florida       |  | Pasco Regional Medical Center                
|                                              |  |               |  | Pasco Medical Plaza Condominium              
|                                             
|PBEC HMA, Inc.                                |  | Florida       |  | Pelican Bay Executive Center                 
|                                             
|Peace River HMA Nursing Center, Inc.          |  | Florida       |  | Peace River Nursing and Rehabilitation Center
|                                             
|Pennington Gap HMA, Inc.                      |  | Virginia      |  | Lee Regional Medical Center                  
|                                             
|Pennington Gap HMA Physician Management, Inc. |  | Virginia      |  |                                              
|                                             
|Personal Home Health Care, Inc. (2)           |  | Tennessee     |  |                                              
|                                             
|Polk HMA, Inc.                                |  | Florida       |  |                                              
|                                             
|Poplar Bluff Regional Medical Center, Inc.    |  | Missouri      |  | Poplar Bluff Regional Medical Center-North   
|                                              |  |               |  | Poplar Bluff Regional Medical Center-South   
|                                              |  |               |  | Piedmont Family Pharmacy                     
|                                              |  |               |  | Three Rivers Lab and X-ray                   
|                                              |  |               |  | Three Rivers Healthcare Home Health          
|                                              |  |               |  | Three Rivers Healthcare Pathology Services   
|                                              |  |               |  | Three Rivers Healthcare Hospice              
|                                              |  |               |  | Piedmont Family Clinic                       
|                                              |  |               |  | Malden Medical Center                        
|                                              |  |               |  | Puxico Medical Center                        
|                                              |  |               |  | Dexter Medical Center                        
|                                              |  |               |  | Bloomfield Medical Clinic                    
|                                             
|Poplar Bluff HMA Physician Management Corp.   |  | Missouri      |  | Ozark Hospitalist Group                      
|                                              |  |               |  | Ozark Medical Management                     
|                                              |  |               |  | Ozark Heart & Vascular Institute             
|                                              |  |               |  |                                              
|Port Charlotte HMA, Inc.                      |  | Florida       |  | Peace River Regional Medical Center          
|                                              |  |               |  | Peace River Home Health Services             
|                                             
|Port Charlotte HMA Physician Management, Inc. |  | Florida       |  |                                              
|                                              |  |               |  |                                              
|                                             
|Punta Gorda HMA, Inc.                         |  | Florida       |  | Charlotte Regional Medical Center            
|                                              |  |               |  | Riverside Behavioral Center                  
|                                              |  |               |  | Wound Care Clinic of Charlotte               
|                                              |  |               |  | North Port Family Health Center              
|                                              |  |               |  | Home Health Services of Charlotte            
|                                              |  |               |  | Charlotte Regional Private Duty Services     

6

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Subsidiaries of
Registrant

|                                             |  | State of      |  | Doing Business
    As               
|-------------------------------------------- |  | ------------- |  | ------------------------------------
|Entity                                       |  | Incorporation |  | (If different from corporate name)  
|Punta Gorda HMA Physician Management, Inc.   |  | Florida       |  |                                     
|                                             |  |               |  |                                     
|Regional Cardiology Center LLC (3)           |  | Mississippi   |  |                                     
|                                            
|River Oaks Hospital, Inc.                    |  | Mississippi   |  | River Oaks Health System            
|                                             |  |               |  | River Oaks Hospital                 
|                                             |  |               |  |                                     
|River Oaks Management Company, Inc. (4)      |  | Mississippi   |  | Preferred Medical Network           
|                                             |  |               |  |                                     
|River Oaks Medical Office Building, Inc. (4) |  | Mississippi   |  |                                     
|                                             |  |               |  |                                     
|Riverview Regional Medical Center, Inc.      |  | Alabama       |  | Riverview Regional Medical Center   
|                                             |  |               |  |                                     
|ROH, Inc. (4)                                |  | Mississippi   |  | Woman's Hospital at River Oaks      
|                                             |  |               |  |                                     
|Rose City HMA, Inc.                          |  | Pennsylvania  |  | Lancaster Regional Medical Center   
|                                             |  |               |  |                                     
|Santa Rosa HMA Physician Management, Inc.    |  | Florida       |  | Santa Rosa Medical Group            
|                                             |  |               |  |                                     
|Sebastian Hospital, Inc.                     |  | Florida       |  | Sebastian River Medical Center      
|                                             |  |               |  | Sebastian River Home Health         
|                                             |  |               |  |                                     
|Sebastian HMA Physician Management, Inc.     |  | Florida       |  | Sebastian Family Walk In Care       
|                                             |  |               |  |                                     
|Sebring HMA Physician Management, Inc.       |  | Florida       |  | Highlands Medical Group             
|                                             |  |               |  |                                     
|Sebring Hospital Management Associates, Inc. |  | Florida       |  | Highlands Regional Medical Center   
|                                             |  |               |  | Highland Medical Group              
|                                             |  |               |  |                                     
|St. Cloud HMA Physician Management, Inc.     |  | Florida       |  |                                     
|                                             |  |               |  |                                     
|St. Cloud Physician Management, LLC          |  | Florida       |  | St. Cloud Medical Group             
|                                             |  |               |  | Medical Solutions for Women         
|                                             |  |               |  |                                     
|Statesboro HMA, Inc.                         |  | Georgia       |  | East Georgia Regional Medical Center
|                                             |  |               |  |                                     
|Statesboro HMA Physician Management, Inc.    |  | Georgia       |  |                                     
|                                             |  |               |  |                                     
|Statesville HMA, Inc.                        |  | North         |  | Davis Regional Medical Center       
|                                             |  | Carolina      |  |                                     
|                                             |  |               |  |                                     
|Statesville HMA Physician Management, Inc.   |  | North         |  |                                     
|                                             |  | Carolina      |  |                                     
|                                             |  |               |  |                                     
|Tequesta HMA, Inc.                           |  | Florida       |  |                                     
|                                             |  |               |  |                                     
|The Surgery Center at Durant, LLC (6)        |  | Oklahoma      |  | The Surgery Center at Durant        
|                                             |  |               |  |                                     
|Tullahoma HMA, Inc.                          |  | Tennessee     |  | Harton Regional Medical Center      
|                                             |  |               |  | Family Medical Center               
|                                             |  |               |  | Family Medical Center of Decherd    
|                                             |  |               |  | Medical Home Health Care            
|                                             |  |               |  |                                     
|Tullahoma HMA Physician Management, Inc.     |  | Tennessee     |  |                                     
|                                             |  |               |  |                                     
|Van Buren H.M.A., Inc.                       |  | Arkansas      |  | Summit Medical Center               
|                                             |  |               |  | Complete Knee Center of Arkansas    
|                                             |  |               |  | Cornerstone Family Clinic           
|                                             |  |               |  | Cornerstone Medical Group           
|                                             |  |               |  | Southwest Impotency Clinic          

7

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Subsidiaries of
Registrant

|                                                |  | State of      |  | Doing Business
    As                     
|----------------------------------------------- |  | ------------- |  | ------------------------------------------
|Entity                                          |  | Incorporation |  | (If different from corporate name)        
|Van Buren HMA Central Business Office, Inc.     |  | Arkansas      |  |                                           
|                                               
|Venice HMA, Inc.                                |  | Florida       |  | Venice Regional Medical Center            
|                                                |  |               |  | Home Health Services of Venice            
|                                                |  |               |  |                                           
|Western Virginia HMA Physician Management, Inc. |  | Virginia      |  | Dickenson Clinic                          
|                                                |  |               |  | Health Associates                         
|                                                |  |               |  | OB\GYN Clinic                             
|                                                |  |               |  | Orthopedic Center                         
|                                                |  |               |  | Pediatric Center                          
|                                                |  |               |  | Wise Medical Group                        
|                                               
|Winder HMA, Inc.                                |  | Georgia       |  | Barrow Regional Medical Center            
|                                               
|Yakima HMA, Inc.                                |  | Washington    |  | Yakima Regional Medical & Heart Center    
|                                                |  |               |  | Yakima Regional Medical and Cardiac Center
|                                                |  |               |  | Yakima Regional Home Health & Hospice     
|                                                |  |               |  | Yakima Regional Medical Center Pharmacy   
|                                                |  |               |  | Toppenish Regional Medical                
|                                                |  |               |  | Toppenish Regional Medical Center Pharmacy
|                                                |  |               |  | Toppenish Community Hospital              
|                                               
|Yakima HMA Physician Management Corp.           |  | Washington    |  | Ahtanum Ridge Family Medicine             
|                                                |  |               |  | Central Washington Endocrine Center       
|                                                |  |               |  | Central Washington Internal Medicine and  
|                                                |  |               |  | Endrocrine Center                         
|                                                |  |               |  | Central Washington Internal Medicine      
|                                                |  |               |  | Central Washington Neurosciences          
|                                                |  |               |  | Central Washington Occupational Medicine  
|                                                |  |               |  | Central Washington Orthopedic Surgeons    
|                                                |  |               |  | Central Washington Rehabilitation         
|                                                |  |               |  | Central Washington Surgical Associates    
|                                                |  |               |  | Emergency Physicians Toppenish            
|                                                |  |               |  | Midvalley Family Medicine                 
|                                                |  |               |  | Terrace Heights Family Physicians         
|                                                |  |               |  | Toppenish Anesthesiology                  
|                                                |  |               |  | YRMC Anesthesiology                       
|                                                |  |               |  | YRMC Cardiology                           

|(1) |  | Subsidiary of Health
      Management Associates, Inc. (Kentucky)
|--- |  | -----------------------------------------------------------------
|   
|(2) |  | Subsidiary of HMA Fentress
      County General Hospital, Inc.   
|   
|(3) |  | Subsidiary of Biloxi H.M.A.,
      Inc.                          
|   
|(4) |  | Subsidiary of River Oaks
      Hospital, Inc.                    
|   
|(5) |  | Subsidiary of Durant H.M.A.,
      Inc.                          
|   
|(6) |  | Subsidiary of Durant HMA
      Surgical Center, Inc.             
|   
|(7) |  | General Partner of Lone Star
      HMA, L.P.                     
|   
|(8) |  | Limited Partner of Lone Star
      HMA, L.P.                     

8

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