Support Documents for 

Significant New Use Rule (SNUR) on 

Premanufacture Notice (PMN) 

P-11-591 

EPA Docket EPA-HQ-OPPT-2011-0942 

EPA SANITIZED Page 1 of 21
Index 

A-001 Structure Activity Team (SAT) Report for 

 PMN P-11-591 

A-002 Initial Review Engineering Report for 

 PMN P-11-591 

A-003 Initial Review Exposure Report for 

 PMN P-11-591 

EPA SANITIZED Page 2 of 21
A-001 

Structure Activity Team (SAT) Report 

for PMN P-11-591 

EPA SANITIZED Page 3 of 21
SAT Report

PMN Number: P-11-0591

SAT Date: 8/30/2011

Print Date: 10/3/2011

Related cases: 

Health related cases: 

Concern levels:

Type of Concern: Health Eco Comments

Level of Concern: 1-2 1

 Persistence Bioaccum Toxicity Comments

1 1 1 PMN

3 1 1 Hyd Pdt

Exposure Based Review:

Health: No

Ecotox: No

Routes of exposure: Health: Dermal Drinking Water Inhalation 

Ecotox: No releases to water

Fate: ; ; Hyd Pdt

Keywords:

 Keywords: 

IRRR-E,S,L

SENS-S,L

INH ONCO

Summary of Assessment:

 Fate:

Fate Summary: P-11-0591

FATE: 

Solid

S = Reacts

Hydrolysis half-life = hr

VP < 1.0E-6 torr at 25 C (E)

BP > 400 C (E)

EPA SANITIZED Page 4 of 21
H < 1.00E-8 (E)

POTW removal (%) = PMN 99 via hydrolysis; then Hyd Pdt 90-99 via sorption

Time for complete ultimate aerobic biodeg = mo

Sorption to soils/sediments = v.strong

PBT Potential: PMN P1B1; Hyd Pdt P3B1

*CEB FATE:

 Health:

 Health Summary: Absorption is nil all routes for the neat material, and poor 

all routes for the low molecular weight fraction when in solution, 

based on physical/chemical properties. There are concerns for irritation to the eye, skin, and 

mucous membranes, dermal and respiratory sensitization, and oncogenicity if the PMN is 

inhaled, based on 

 Ecotox:

Test 

Organism

Test 

Type

Test End 

Point

Predicted Measured Comments

fish 96-h LC50 *

daphnid 48-h LC50 *

green algal 96-h EC50 *

fish _ chronic value *

daphnid _ chronic value *

algal _ chronic value *

Sewage Sludge 3-h EC50 _

Sewage Sludge _ Chronic Value _

Ecotox Values Comments: Predictions are based on SARs for nonionic polymers; SAR 

chemical class = ; solid 

with mp unknown (P); S = reacts with water at 25 C (P); pH7; effective concentrations based 

on 100% active ingredients and nominal concentrations; hardness <150.0 mg/L as CaCO3; and 

TOC <2.0 mg/L;

Factors Values Comments

Assessment Factor 10

Concentration of Concern 

(ppb)

*

SARs nonionic polymers

SAR Class

Ecotox Factors Comments: 

 SAT Chair: J. Kwiat

EPA SANITIZED Page 5 of 21
A-002 

Initial Review Engineering Report 

for PMN P-11-591 

EPA SANITIZED Page 6 of 21
p110591.eng

INITIAL REVIEW ENGINEERING REPORT : 

PMN: 11-0591

Focus Ready Draft 9/8/2011

ENGINEER: Austin \ JAS

PV (kg/yr): 

SUBMITTER: 

USE:

OTHER USES:

MSDS: Yes Label: No

Gen Eqpt: Chemical-resistant, impervious gloves (butyl

rubber gloves are recommended. // safety eyewear (safety

glasses with side-shields are recommended). // In some

cases,| fume scrubbers, filters or engineering

modifications to the process equipment will be| necessary

to reduce emissions to acceptable levels.

Respirator: Use a properly fitted, air-purifying or

air-fed respirator complying with an approved standard if

a risk assessment indicates this is necessary. Respirator

selection must be based on known or anticipated exposure

levels, the hazards of the product and the safe working

limits of the selected respirator.

Health Effects: Flammable liquid and vapor / may be fatal

if inhaled / causes respiratory tract, skin and eye

irritation / may cause allergic respiratory and skin

irritation / may cause sensitization by inhalation or

skin contact / contains material that may cause target

organ damage, based on animal data / exposure to

decomposistion products may cause a health hazard.

TLV/PEL:

CRSS :

 

Page 1

EPA SANITIZED Page 7 of 21
p110591.eng

 

 

Consumer Use: 

SAT (concerns) (08/30/2011):

Related Cases and Related Cases and Misc SAT Info:

Ecotox Related Cases: 

Migration to groundwater: Negligible

PBT rating: P3B1T1 PMN: P1B1T1 // Hyd Pdt: P3B1T1

Health: 1-2 Dermal, Drinking Water, Inhalation

Eco: 1 No releases to Water

OCCUPATIONAL EXPOSURE RATING: 1-2B

NOTES & KEY ASSUMPTIONS:

Generated by the 06/07/2005 version of ChemSTEER. 

 

 

 

POLLUTION PREVENTION CONSIDERATIONS:

EXPOSURE-BASED REVIEW: No

INITIAL REVIEW ENGINEERING REPORT 

PMN: 11-0591

 

Page 2

EPA SANITIZED Page 8 of 21
p110591.eng

 

 

 

Page 3

EPA SANITIZED Page 9 of 21
p110591.eng

INITIAL REVIEW ENGINEERING REPORT : 

PMN: 11-0591

 

Page 4

EPA SANITIZED Page 10 of 21
p110591.eng

 

 

 

 

Page 5

EPA SANITIZED Page 11 of 21
A-003 

Initial Review Exposure Report 

 for PMN P-11-591 

EPA SANITIZED Page 12 of 21
September 7, 2011 Page of 

INITIAL REVIEW EXPOSURE REPORT (IRExR) 

 Chemical ID: P-11-0591 Reviewer: Kwon/JB 

 

 

Results Table: Dose, Concentration, and Days Exceeded Results Summary 

Exposure Scenario1 Water Landfill Stack Air Fugitive Air 

Drinking Water Fish Ingestion 

ADR LADD ADR LADD 7Q104 

CC = 

PDM 

Days 

Exceeded 

LADD ADR LADD ADR LADD 

Release 

activity(ies)2; 

exposure 

calculation(s)3 

mg/kg/day mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day 

 

 

 

 

1 Exposure scenario titles consist of release activity followed by exposure calculation abbreviation. 

2 Release activities are from engineering report's Manufacturing (Mfg), Processing (Proc) and Use release 

activity labels. 

 Multiple release activities are combined in one exposure scenario if their releases occur at same location. 

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and 

Probabilistic Dilution 

 Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. 

 CC is the aquatic concentration of concern. 

4 This column displays concentration values for the 7Q10 streamflow, which is defined as the average daily 

streamflow of the seven consecutive days of lowest flow within a ten year period. 

Remarks: 

EPA SANITIZED Page 13 of 21
September 7, 2011 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-11-0591 Assessor: Kwon/JB 

ENVIRONMENTAL RELEASES 

 Scenario#:1 Number of Release Sites: 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 14 of 21
September 7, 2011 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-11-0591 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 1 Number of Sites: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION:

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 

ALL 10 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot mg/kg/day mg/kg/day 

LADCpot mg/L mg/kg 

Acute 

ADRpot mg/kg/day mg/kg/day 

SIC Code Comments: 

EPA SANITIZED Page 15 of 21
September 7, 2011 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-11-0591 Assessor: Kwon/JB 

ENVIRONMENTAL RELEASES 

 Scenario#:2 Number of Release Sites: 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 16 of 21
September 7, 2011 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-11-0591 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 2 Number of Sites: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: 

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 

ALL 10 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot mg/kg/day mg/kg/day 

LADCpot mg/L mg/kg 

Acute 

ADRpot mg/kg/day mg/kg/day 

SIC Code Comments: 

EPA SANITIZED Page 17 of 21
September 7, 2011 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-11-0591 Assessor: Kwon/JB 

ENVIRONMENTAL RELEASES 

 Scenario#:3 Number of Release Sites: 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 18 of 21
September 7, 2011 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-11-0591 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 3 Number of Sites: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: 

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 

ALL 10 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot mg/kg/day mg/kg/day 

LADCpot mg/L mg/kg 

Acute 

ADRpot mg/kg/day mg/kg/day 

SIC Code Comments: 

EPA SANITIZED Page 19 of 21
September 7, 2011 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-11-0591 Assessor: Kwon/JB 

ENVIRONMENTAL RELEASES 

 Scenario#:4 Number of Release Sites: 

 Release Activity: 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 

EPA SANITIZED Page 20 of 21
September 7, 2011 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-11-0591 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 4 Number of Sites: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: 

SIC-CODE (S): EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 

ALL 10 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot mg/kg/day mg/kg/day 

LADCpot mg/L mg/kg 

Acute 

ADRpot mg/kg/day mg/kg/day 

SIC Code Comments: 

EPA SANITIZED Page 21 of 21