# Support Documents for Significant New Use Rule (SNUR) on Premanufacture Notice (PMN)
P-11-591

EPA Docket EPA-HQ-OPPT-2011-0942

# Index A-001 Structure Activity Team (SAT) Report for PMN P-11-591 A-002 Initial Review Engineering Report for PMN P-11-591 A-003 Initial Review Exposure Report for PMN P-11-591

# A-001 Structure Activity Team (SAT) Report
for PMN P-11-591

## SAT Report PMN Number: P-11-0591 SAT Date: 8/30/2011 Print Date: 10/3/2011

Related cases : Health related cases:

Concern levels : 

### Type of Concern: Health Eco Comments Level of Concern: 1-2 1

Persistence Bioaccum Toxicity Comments 1 1 1 PMN 3 1 1 Hyd Pdt

Exposure Based Review : Health: N o Ecotox: N o
Routes of exposure : Health: Dermal Drinking Water Inhalation Ecotox: N o releases to water Fate: ; ; Hyd Pdt
Keywords : Keywords: IRRR-E,S,L SENS-S,L INH ONCO
Summary of Assessment :

Fate : Fate Summary: P-11-0591 FATE: Solid S = Reacts Hydrolysis half-life = hr VP < 1.0E-6 torr at 25 C (E) BP > 400 C (E)

### H < 1.00E-8 (E) POTW removal (%) = PMN 99 via hydrolysis; then Hyd Pdt 90-99 via sorption Time for complete ultimate aerobic biodeg = mo Sorption to soils/sediments = v.strong PBT Potential: PMN P1B1; Hyd Pdt P3B1 *CEB FATE:

Health : Health Summary: Absorption is nil all routes for the neat material, and poor all routes for the low molecular weight fraction when in solution, based on physical/chemical properties. There are concerns for irritation to the eye, skin, and mucous membranes, dermal and respiratory sensitization, and oncogenicity if the PMN is inhaled, based on

Ecotox :

Test Organism Test Type Test End Point Predicted Measured Comments

fish 96-h LC50 * daphnid 48-h LC50 * green algal 96-h EC50 * fish

_ chronic value * daphnid

_ chronic value * algal

_ chronic value * Sewage Sludge 3-h EC50

_ Sewage Sludge

_ Chronic Value

_ Ecotox Values Comments: Predictions are based on SARs for nonionic polymers; SAR chemical class = ; solid with mp unknown (P); S = reacts with water at 25 C (P); p H7; effective concentrations based on 100% active ingredients and nominal concentrations; hardness <150.0 mg/L as CaCO3; and TOC <2.0 mg/L;

Factors Values Comments Assessment Factor 10 Concentration of Concern ( p pb) *

SARs nonionic polymers SAR Class

Ecotox Factors Comments:

SAT Chair: J. Kwiat

# A-002 Initial Review Engineering Report
for PMN P-11-591p110591.eng INITIAL REVIEW ENGINEERING REPORT : PMN: 11-0591 Focus Ready Draft 9/8/2011 ENGINEER: Austin \ JAS PV (kg/yr):

SUBMITTER:

USE:

OTHER USES:

MSDS: Yes Label: No Gen Eqpt: Chemical-resistant, impervious gloves (butyl rubber gloves are recommended. // safety eyewear (safety glasses with side-shields are recommended). // In some cases,| fume scrubbers, filters or engineering modifications to the process equipment will be| necessary to reduce emissions to acceptable levels. Respirator: Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Health Effects: Flammable liquid and vapor / may be fatal if inhaled / causes respiratory tract, skin and eye irritation / may cause allergic respiratory and skin irritation / may cause sensitization by inhalation or skin contact / contains material that may cause target organ damage, based on animal data / exposure to decomposistion products may cause a health hazard. TLV/PEL:

CRSS :

Page 1p110591.eng

Consumer Use: SAT (concerns) (08/30/2011): Related Cases and Related Cases and Misc SAT Info: Ecotox Related Cases: Migration to groundwater: Negligible PBT rating: P3B1T1 PMN: P1B1T1 // Hyd Pdt: P3B1T1 Health: 1-2 Dermal, Drinking Water, Inhalation Eco: 1 No releases to Water
OCCUPATIONAL EXPOSURE RATING: 1-2B
NOTES & KEY ASSUMPTIONS: Generated by the 06/07/2005 version of ChemSTEER.

POLLUTION PREVENTION CONSIDERATIONS:

EXPOSURE-BASED REVIEW: No

INITIAL REVIEW ENGINEERING REPORT PMN: 11-0591

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Page 3p110591.eng INITIAL REVIEW ENGINEERING REPORT : PMN: 11-0591

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# A-003 Initial Review Exposure Report
for PMN P-11-591September 7, 2011 Page of



### INITIAL REVIEW EXPOSURE REPORT (IRExR)

Chemical ID: P-11-0591 Reviewer: Kwon/JB

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air Drinking Water Fish Ingestion
ADR LADD ADR LADD 7Q10 4
CC = PDM Days Exceeded LADD ADR LADD ADR LADD

Release activity(ies) 2 ; exposure calculation(s) 3 mg/kg/day mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day

1 Exposure scenario titles consist of release activity followed by exposure calculation abbreviation. 2 Release activities are from engineering report's Manuf acturing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location. 3 Exposure calculations are Acute Dose Rate (A DR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern. 4 This column displays concentration values for the 7Q 10 streamflow, which is defined as the average daily streamflow of the seven consecutive days of lowest flow within a ten year period.

Remarks:September 7, 2011 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P-11-0591 Assessor: Kwon/JB

ENVIRONMENTAL RELEASES

Scenario#:1 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr:

Per Site Release: (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:September 7, 2011 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P-11-0591

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 1 Number of Site s: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: SIC-CODE (S): EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50

ALL 10

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot mg/kg/day mg/kg/day

LADC pot mg/L mg/kg

Acute

ADR pot mg/kg/day mg/kg/day

SIC Code Comments:September 7, 2011 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P-11-0591 Assessor: Kwon/JB

ENVIRONMENTAL RELEASES

Scenario#:2 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr:

Per Site Release: (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:September 7, 2011 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P-11-0591

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 2 Number of Site s: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: SIC-CODE (S): EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50

ALL 10

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot mg/kg/day mg/kg/day

LADC pot mg/L mg/kg

Acute

ADR pot mg/kg/day mg/kg/day

SIC Code Comments:September 7, 2011 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P-11-0591 Assessor: Kwon/JB

ENVIRONMENTAL RELEASES

Scenario#:3 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr:

Per Site Release: (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:September 7, 2011 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P-11-0591

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 3 Number of Site s: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: SIC-CODE (S): EX POSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50

ALL 10

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot mg/kg/day mg/kg/day

LADC pot mg/L mg/kg

Acute

ADR pot mg/kg/day mg/kg/day

SIC Code Comments:September 7, 2011 Page of

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P-11-0591 Assessor: Kwon/JB

ENVIRONMENTAL RELEASES

Scenario#:4 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases: (kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge Release Days/yr:

Per Site Release: (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:September 7, 2011 Page of

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P-11-0591

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO #: 4 Number of Site s: RELEASE ACTIVITY:

SIC-CODE DESCRIPTION: SIC-CODE (S): EX POSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

PLANT TYPE % ILE FACILITY STREAM FLOW (MLD) STREAM CONC. ( μ g/l)

Harmonic

Mean 30Q5 7Q10 1Q10 Harmonic Mean 30Q5 7Q10 1Q10

ALL 50

ALL 10

DRINKING WATER AND FISH IN GESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion

Units 50% 10% 50% 10%

Cancer

LADD pot mg/kg/day mg/kg/day

LADC pot mg/L mg/kg

Acute

ADR pot mg/kg/day mg/kg/day

SIC Code Comments: