Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

1. Company Name and Address

0253 - Oxamyl

Chemical # and Name: 103801

Oxamyl

27-Oct-2011

GENERIC

ID # GDCI-103801-859

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Environmental Fate Data Requirements (Conventional 

Chemical)

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

835.4400

850.4100

850.4150

850.4400

850.1025

850.1035

Anaerobic aquatic metabolism

Terrestrial Plant Toxicity (Seedling Emergence)

Terrestrial plant toxicity, Tier 1 (vegetative vigor)

Aquatic plant toxicity test using Lemna spp. Tiers I 

and II

Oyster acute toxicity test (shell deposition)

Mysid acute toxicity test

0253 - Oxamyl

Chemical # and Name: 103801

Oxamyl

27-Oct-2011

GENERIC

ID # GDCI-103801-859

C,A,B

C,A,B

C,A,B

C,A,B

C,A,B

C,A,B

TGAI

TEP

TEP

TEP

TGAI

TGAI

24

12

12

12

12

12

Page 1 of 

(10)

(4, 6, 15)

(3, 8, 16)

(1, 12, 17)

(7)

(9)

N

N

N

N

N

N

2
Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical)

850.1350

850.1400

850.2100

850.3040

870.7800

Mysid chronic toxicity test

Fish early-life stage toxicity test

Avian acute oral toxicity test

Field testing for pollinators

Immunotoxicity

0253 - Oxamyl

Chemical # and Name: 103801

Oxamyl

27-Oct-2011

GENERIC

ID # GDCI-103801-859

C,A,B

C,A,B

C,A,B

C,A,B

C,A,B

TGAI

TGAI

TGAI

TEP

TGAI

12

12

12

24

12

Page 2 of 

(2)

(2)

(11)

(5, 13)

(14)

N

N

Y

Y

Y

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0253 - Oxamyl

GDCI-103801-859

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

The 40 CFR Part 158.660 indicates that either the TEP or the TGAI may be used for aquatic plant testing. However, use of the TEP is preferred to a TGAI study with a standard solvent.

Since chronic toxicity studies involving freshwater fish and invertebrates indicate that oxamyl affects reproduction endpoints of freshwater animals (MRIDs 40901101 and 45067801), data are 

also required for estuarine / marine fish and invertebrates.

Refer to public draft guideline 850.4250 for guidance on Tier II vegetative vigor testing.

Refer to public draft guideline 850.4225 for guidance on Tier II seedling emergence testing.

Data are required to fulfill this guideline due to concerns that oxamyl may affect honey bee colonies.

Data are required for tomatoes only.

Data are required for the Eastern oyster.

Data are required for six species of dicots from at least four families, one species of which is soybean (Glycine max). Data are required for four species of monocots from at least two families,

one species which is corn (Zea mays). At least one of either the monocot or dicot species must be a root crop.

Data are required for mysid shrimp.

Data are required for acidic systems in which abiotic degradation is minimized. Inclusion of a ferrous iron-poor system is also required. Multiple sampling intervals should be included within the 

first hours after application in the event that degradation is rapid.

Data are required for a passerine species. A passerine study protocol must be submitted to the Agency for review and approval prior to initiation of this study. The draft protocol must be 

submitted to EPA within 90 days of receipt of this DCI.

Data are required for a duckweed species.

A study protocol must be submitted to the Agency for review and approval prior to initiation of this study. The draft protocol must be submitted to EPA within 90 days of receipt of this DCI.

A protocol must be submitted to the Agency for review and approval prior to study inception. The draft protocol must be submitted to EPA within 90 days of receipt of this DCI.

A Tier II study is required. For oxamyl, the Agency already has an acceptable Tier I seedling emergence study (MRID 45546101). However, because a no-effect value could not be determined 

for tomatoes, Tier II data are required and are being called-in through this DCI. The purpose of a Tier II study is to establish both a definitive No Observed Adverse Effect Concentration (NOAEC),

or alternatively, a concentration at which there is a 5% observed inhibition effect (IC05), to be used in a risk assessment and effects determination for endangered or threatened species (listed 

species), and a definitive IC25 (concentration at which there is a 25% observed inhibition effect) for assessing risk to non-listed nontarget plants.

A Tier II study is required. For oxamyl, the Agency already has a supplemental Tier I vegetative vigor study (MRID 45546102). Due to the limitations in the available Tier I study and because 

oxamyl can be used as a plant growth regulator, Tier II data are required and are being called-in through this DCI. The purpose of a Tier II study is to establish both a definitive No Observed 

Case # and Name:

DCI Number:

Page: 1 of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

A - Terrestrial food crop

B - Terrestrial feed crop

C - Terrestrial nonfood crop

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0253 - Oxamyl

GDCI-103801-859

17

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Adverse Effect Concentration (NOAEC), or alternatively, a concentration at which there is a 5% observed inhibition effect (IC05), to be used in a risk assessment and effects determination for 

endangered or threatened species (listed species), and a definitive IC25 (concentration at which there is a 25% observed inhibition effect) for assessing risk to non-listed nontarget plants.

A Tier II study is required. A supplemental study is available to characterize the effects of oxamyl on vascular aquatic plants, specifically duckweed (MRID 45546103). This toxicity study was 

considered scientifically sound, but was classified as "supplemental" due to a lack of constant exposure of test organisms to the test material. Therefore, there is uncertainty associated with 

the results of this study in that the endpoint obtained may underestimate the effects of oxamyl on aquatic vascular plants. Tier II are required and are being called-in through this DCI. The 

purpose of a Tier II study is to establish both a definitive No Observed Adverse Effect Concentration (NOAEC), or alternatively, a concentration at which there is a 5% observed inhibition effect 

(IC05), to be used in a risk assessment and effects determination for endangered or threatened species (listed species), and a definitive IC50 (concentration at which there is a 50% observed 

inhibition effect) for assessing risk to non-listed nontarget plants.

Case # and Name:

DCI Number:

Page: 2 of 2
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 0253 - Oxamyl

Page: 1 of 1

352 E. I. DU PONT DE NEMOURS AND COMPANY

(S300/419)

Co. Nr. Company Name Agent For Company

1007 MARKET STREET

Address City ZIP

WILMINGTON 198980001

OMB Approval 2070-0174

State

DE

 DCI Number: GDCI-103801-859
LINKS TO FORMS:

The pesticide registration forms that are listed below can be found at:

http://www.epa.gov/opprd001/forms/

Link to Confidential Statement of Formula and Instructions (Form # 8570-4)

http://www.epa.gov/opprd001/forms/8570-4.pdf

Certification of Attempt to Enter Into an Agreement With Registrants for 

Development of Data (Form # 8570-32)

http://www.epa.gov/opprd001/forms/8570-32.pdf

Certification With Respect to Citation of Data (Form # 8570-34)

http://www.epa.gov/opprd001/forms/8570-34.pdf