# EPA Registration 264
‐418 Vol.2

# JocJ 

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# " ,.....'·21·"
United srlru 

## Roglstration opp Identifier Numb., 

# oEPA Environmental Protection Agency 

# 7.. Amendment W

..hinoton. OC 20460 

## Other

,for 

# , I- 

### I I
I. CcmponylPloducl Number 

### 2. EPA 3. Plo!,o$od Clu:tific.tkln 

### 264-418 iI 

# oNano 

# o Rul/iclocj 

# .i;,c;:;b-**,'N~"** 

# ','!' ,?? CaUon and T obaCGQ 5. Ntml .nd Addrus 01**AP9~e.nl** Ilnclud. ZIP Cod_}**~._~.P'dit'd** 

### Reveiw. In accordance with

### FfFRA Seelion 31en3!**~axo~**

### CropScionco

### ~~!!f!. 'my ploduct is sfmRar or identical in compositfon and fabeUng



## .**~-R;** 120t4.2T.W.AfexanderOrive 1 Ifl<lflyfe Palk, NC 27709 

### Reg. No.



# DCh."k it 1111$ i$ 

### .newaddr,ss 

### Product Name


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# [2] Amarnllnenl·

### f.pl~n b.lo

..... 

# U FiMI printed lab,11 in replonlo 10 Agency 1IIIel detod 

# 18 '''''m'''''.,., ••,•••• ,.

# AO'M' "U,' ,...,. 

# o**~M.** Too'

......pile.II,,".
NotiUe.lion· Expl.in billow. 

# oOthll. Exp/&in bolo

..... 

### Explanation: 

## us. oddilion41 Plgoflf i/ 

### ne.:usory. 1"'01 l"tlion [OM S,,'uon 11.1 REGFEE: Amem!menlloRegiWation· Re!}lsltatk!n 01 Altemale Coolldentiaf S[!Ilements01 Fonnwa (CSF$). F:ulllllck, FEE: NotApplicable. JUSTIFICATION: Tho ploposedAllcmaleCSFsreReel eMelamoodlOOnl.$ 10 tho CSFfot the MUP, 8aw- 250 (EPA Reg. No, 264.0$11). ortho US!) mMW MUPs forwhich**App~caUon&**f<lf RCfJi![rnliolliNnottdm&1IIs MIl bIllng submllied coocorrcnUywiththiS subtnl.$s!oo. No nowdala IlIGuiloo lor [no PfOPO$Cd amendmentto [no subjm;:t ondusn producl-**~Iy** 00 OJ6sl[nG dlliaonmo III [he EPA. No chlll'lgu made [0 the eomposll1Moftho and U$OptOOwct. Cutailed jvsll5t:.alloru:l provided IttIho attached 1etter. COUTACT: OanlelloA.l.'irochcHo, 9[9154S,27!8;**cMa~;** Da.n!eHo,Lolochel!oObAyltreropfdCIlCII.CQm. 

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# . ; (9t9) 549·27fB

.

### _~~_ ••:. 

### Certification t;, O,[:t!r-""don I Artily th,[ tho $'-I<If1\MIs I hava made on lhis fOlm and lIII,nethmants 1I'!alelO ola tnlo. 1ICC:llre[a and



# . : ,:"ee ••• lecknowl.cge 11u[ any kno

....llnglly /fl" or mi$/udinO ,""_n[moybe punishable by 1In11 

### : (S""",edl both under 

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# ..:: • 

# .. Reg!slration Manager, Inseclicides 

## • 

## • • •••• • '4. Typld Name 

# ..:. • • 5.01[' 

## •••• Danielle

## A. Larochelle September 17. 2004 

## • 

# • ••••



# .

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• BaverCropScience

November 5, 2004

IJoCUntellt 

### Processing Desk (WD) Office ofPesticide Prugrams (7504C) 

### C.S, Environmental Protection Agcucy 

### ISOI South Bell Street Arlington, Virginia 22202-450I Attenliun: Ms. Linda Arrington, RD



### DearMs, Arringtou,

Rc: \Vitbdrawal ofApplications for Pesticide Amendment 

### End**u.~c** 

### Products Containing Ethepbon
On September /7, 

### 2004 BayerCropSciem:e submitted sL'"verul application:> for pestici(ie amendments tor

.. 'od 

### usc products c])Otilining 

### the active ingredientEthcphon. The proposed itnlClldntcnts 

### reflected a) changes whIch are not yet approved for the manufacturing llse 

### product Blls..' 250 Confidential SrnlCmCl!lS 

### ofFormula (CSFl» and b) the usc ofmanufacturillg 

### usc product'i which arc llol yel registcred, Base 211 Ethcplton and Etbcpbon \1al!ni.1eturillg C(Jl!centratc (applications also

...ubmittcd 9lJ7J2004). \Ve 

### are therefore withdrawing the 

### applications submitted 

### flu- the following end use products:



### ETHREL1t bm.nd Ethephon Plant 

### Growth Regulator (ForPi!!eapple and

Sugarcalle)**~-** 

### EPA Reg. No. 264-257**FLOREU~'.'** 

### brand Ethephon Phlnt Growth Regulator- EPA Reg. No. 264-263 ETI-lREL® brand Eth"'phon Plant Regulator

- EPA Reg. No. 264-267 CERON£¥: 

### brand Ethephon Plnnt Regulator

- EPA Reg. No.**264~377**

### PREpr~l 

### brand Ethcphon Plant Regulator roreQUOl!

- EPA Reg. No. 264·380 pR.EpTM 

### brand Ethcpholl torCotton tllld TubaeCl)

- EPA 

### Reg. 1\0. 264-4 [8 

### FLOREL® brand GjR Plant Gro\\.1h Regulator

- EPA Reg. No. 264-543 FfN1SHltr (j 

### PRO [Iarvest Aid tor Cotton· EPA R"'g. No.**264~**

### 703
Furyourconvenicrn.'c, copies olthe App[kations for Pcsticide Amendmeltt 

### ,EPA Foml 

### 8570-1) submitter! on September [7 for these- proullCL<; 

### are attached for referenec. Ple,lsc schedule the review oltheApplications submitted OJ! Sept

.. 'mher 

### 17'" proposing CSF amclldments for Base 250 lind 

### the registration oftlte llew

/l2



# 3

# •



# • November 5, 2004 

### Ms. Linda Arrington 

### Page 2of2



### Withdrawal ofApplications for 1)I..'Sticidc Amcndmcnr (Cont'd)

manufacfuring usc products, Dase 2!! Ethephon and Efhcphon Manufacturing Concentrate. Once 

### these aCfions 

### arc complefed, the amendmenfs 

### for rhe producfs listed above 

### will be rc-submiffcd.


### Please leI me know if

### you need any additional iniOrmatioll. Yon C311 

### reach me 31 (Y!9) 549<17!R 

### or hy c-mni! at**D.gI:!l~!lu&;:~i',.,",Hr~tw)£Tgill!-.'t£_Jf'_IJ.t-t_C{}.!l!** 

### .. Sincerely,



### Dank!!c.l\. L.1fochc!!c 

### RcgistrmioJl Product /I,'!unagcr

cc: Ms. Cynthia Giles Parker. RDiPM22

AltacbmcnlS

CarT. t\o_ daLll:!-J)4



# 4

# ,



# • BayerCropScience

Kovembcr 

### 5,2004



### DllcumentProcessing fk-5k ('1'.'0) 

### Office ofPesticide Pmgroms (7504C) U.S. Environmental Pwtection AgCl1C), 

### 1801 South Bell SlreC! Arlington, Virginin22201-4501 Attention:**~1s.** 

### Linda Arrington, 

### Jill

Dear Ms. Arrington,
Re: 'Vithdrawal ofApplications for Pesticide Amendment 

### End Use Produtts ContainingEtbcptlOn By!""**(;,;pS~,!,,~.~** 1;11" r" C !k" 1::{!'>\ PTI'\ 

### lie ;:710!) "i.1**S!S~As<nnL** On 

### September 17, 2004 BayerCropSeiencc submitted severnl applications forpesticide nmendmeIlls forend useproductstontainingthe active ingredicn\ Et1tephou. The proposed amendments reflected a)**change~** 

### which
are notyet ttppruved for the manufacturing

# uscproduct Base 250 Confidential**Slatcmeul~** 

### ofFonnula (CSFs) andb) the Use ofmanufacturing usc prodUCl" wllie/; are 1101 yel registered, Base2J I Ethephoo andEtbephon Manufacturing Concentrate (applic.1.lions also submittt.:"<i 9//7/2004). We are 

### therefore withdrawi11g 

### the applications 

### submitted for the foJ/owil1g cnd tLSe 0'('

### i,C'}(

## ~ products: 

## Itc-'t'

## t' 0 V'I

_

# ~J

# .:tt..,,/: 

# ""'-w.::t:s-

# L12.::.... D3.5-i\l7,2/S771 't 1'1 . 5 e'"

. ETHREL® brand Ethcphon PlantGrowth Regulator (ForPineapple and wl<V\ • 

### Sugarcane)

### ~~ EPAReg. No. 264-257 FLOREL®brand Etbcp/ion PlaUT Growth Regulator

... EPA Reg. Nu, 264-263 

### 1)

## :SSl

## "37

## 3js-771

# Y. 2.0 ETIJREL® brand Ethcphon Phmt Regulator

... EPA Reg. t{o. 264

...267 D 

# :s S 

## 1"'3" 7

## L-f / S 

## 771 L{:2.. 

## ! CERONE:[t brandEthepbon Plant 

### RCb'1lJator

... EPA Reg. No. 264·377 

### "0.3 S l 

### '87.s

## IS77 !L{

# '22. PREplM brnnd Ethephon PlautRegulDlor for Cotton

... EPA Reg. No. 264-380 

## D35 I'g

# 7b/ S 77

## (Y2.. 3: PREPTh! 

### br:md Ethephon for Colton and Tobacco

... EPA Reg. No. 264-4 J

### S 

## D 3 

## S l 

# '8 77/S 7 7 !

# Lf2 Lj FLOREL®brnnd 

## GiR Plant Growth Regl1JlltOr- EPA 

### neg. No. 264-543 

## 1)35I'g'

## 7'6/ S 

## 77f

# Lf2 S
FINfSH® 6 PRO Harvest Aid fur COlion

- 

### EPA Reg. No. 264·103 

## t> 

## 35**(~7 ~/.s7** 

## 71LJ. 

## 2 C**4~"<"-~** 

### For your convenience, copies ofthe Applications for Pe.\licide Amendmcn(**(l~PA**

### Fonn 8570-1) submitted on September 17 for these pmduets arc attached for referente.
Please schedule Ihe review ofthe Applications submitted on Septcmber 17!"**prop().~ing** 

### CSF ame11dments for Basc 250and the tcgis-:rlllion ofthe new

/12 

### , ,

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# 5

## , •



# •

• November5, 2004 

### Ms. Linda Arrington Page 2 of2



### Withdrawal ofApplications for Pesticide Amendment (Cont'd)

manufacturing usc producls, Ha..<;e 211 EtllCphon and Ethephon Manufacturing 

### Concenlrllle. Once these actiuns i:Hl:

### CllUlplcled, the amendments for the products listed above 

### will be re·submitted.
Please leI me know if

### YOll need tiny 

### IJdditional iluormation. 

### You can rellc!; me at (919) 549-2718 orby e-mail at**ll:Jlli8lwdrr:~bc!!c'd'haxIT..cJ:!}Jllii.£!!.£.S@!.D.** 

### Sincl:rcly,

Danielle A. Larrn:hel1e Registration Product Manager



### cc: Ms. Cruthia Giles Parker. RDIPM22

Attllchmcnb

Corr. No. daU 12-04



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### D..-:sl 1\\'Di 

### (ltYic.: or Peo.licldc**Pfogl'.illl~** (75il..J() !' S EnVirollll);.'!II:d PI{I!cclloll**A!!':Il"~'** 

### i i.;()! Suuth IkE '>Ir<:rt \ri!l1ghln. \ irglillil**~2202-45(Jl** ·\IfClllion, ivh 1.lI1d.1 :ll'rJllpIUIl. Ttl)**R~'** 

### Wilhtlnmal (l(

### AppUclllinn.\ lor PcstiddL' Amcmlnl{'llt 

### End CSt: PrndlicH C(lIlI:lillin/.i Elhcpilon /

On Scptr:mD<:r 

### \1 > 2()O"; B:1Y("I" CrDpS:.:ienc..: :.u!mll\\ed 

### s\:\'na\ ;lppiIC-:1Illllh for ptstil:id..: ;lrlicOdn1(';1ts for ,'1)(1 Ih(, ptnducts containing lilt :\;:llvC 

### mb'l'cd'lL"lIl Hh..:pihll:. 

### Tilt,**prop0~i.'d ;llllclltlmepl~**  

### n:i1c..:-r..:d ai c!i:ll1g;:s WhlCh**3r~'** DDt yet :lppliH

### cd {,:lr**IhL~** Illanlli:H:nlfmg the prl)Jucl 

### Hil-..;e 250 COllfidcnlui StIICl1i:.:n;s 

### 1)1'hmll1li,1 (CSFs

### 1:iIlJ hi lht: use 

### oflllanlilaCllli"ing 11:'.(' 

### pmdw:t:s whidl 

### :lrc n,)! yet n:gLslcrd, 13.:15<': 211 Elln:pllllil :Inti**Uil~pholl** Mantii;ICl1lnng (\IIlCnl1rnlL'**(aprnC<llI011~** QISll SOi.llll!U<!d \)' Ii.'::'n(4). We ;ire: 

### 1ilL'rcfon: wllhdwwing !lle :ljlp!ICllioll:> 

### SllbfHllH.:d [,)r lht**~)ilowing** end Ib": pr(llhlcLS:

I-,TII

### RJ: Lji, hr;!l1d l',!hcpholl 1'1,1111 

### r;-r,Hvth Regulaln:- ll-()r Pi Ilcappic and**S\l~3r<,';lIlC:)'~ I~PA**  Reg. 1'.11. 

### 26-l':157 

### FLORH 11 hr;lIld 

### HhepiJlIll Planl UrO\'.'lh 

### Rcgui:Hl1r' rI'A Reg. 1\0. 264-2(,] f-T! IRFLJ<, bra no Elllcpiloo 1'!:1111 Regu la Ilir

- I--.Pr\ R<.'g. 1\ Ii. 264-267 

### (THO:-JFA br:lll<:i Llllt.'piJlJll Phllt! R<:g.uhllir FPA Reg. 1\0,**~6-1,.n:** pgEl'r,! brand FI11Cpl10ll Planl R<!glllahrr I'or('nllnll· EPA Reg. 

### 1\1) 2fJ4-3XO !'RLP\V (;1':11111 

### Hlh:piJoll fM CI,II()n3I1U Toh:IL';;,)· I--PA !l.eg. Ko 

### ':(,4-..jiX
FLOIU?L lZ bnlHti 

### CFR Pbnl Growth**Kq;'ll~nli)r** - IJIA 

### Reg. 1\0_**26'-\-:;4_~** 1-1\11:-;11**~** () PRU**11'1r;'{:~1** Aid )(lrO,l1ol1

- i:PA. Reg.**~o. 2(,~,** 7fB

1-'01 y0\1r C\lil\-\:lW:llce. COp1C_-:' IJrUw Applicatwlt., jilr**f'c~li';lde** AnIClltil11'-'IlJ iI-,rA ronn K570·! I 'lIhlllillC-d on 

### Sep!<:mh-cr I'; [i)r**Ih~se** prudlk1s :lfC :l1(;IL'!l,'1i 1(11 n:fcr..:nc\"
ric;lsL S,'hLJllk the ret lew ':IftiTL !\pplit<l!IIJIlS ';1I!mlined 0)\ Seplel1lhcr I7" (1rl)p(,';ll1g 

## r Sf ;)!ilelldmcnl" fill' 1},I'c**~511** alld tile**,egl~lr<llH'n** l,r IIIL 11(\\

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### Page.2 of:':



### WilhdnlWal 

# DrApllliratillm ftJr 

### Pc')ticidc Amendment (Cont'd)

manllfaZ'tllnng n;.;;:**pn)'!II-(!~,** lkh,: 21 

### I Elhepil()l1 :md 

### l"lhr:rh()J1 \iamd:l{,llIring**C(ln~'cnlraJe,** (JIK:': thes;;**,1(:)1(l1l~ m~'**  {;l)mpkled. tile .l!l1.:ndmt.'IlI_" j(lr lh<.:**pn'Klil(l~** 11S((.'d ahove 

### will b<: rt:-!.lIbntlllcd



### D:midi.;: A !.amendk Ikgistnlllllil 

### Proilud \LHwg..:r



# 8

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## ----------,__**'''~**____________**~u~**

_ ______________________**~**



# "'- '" ",

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# ,

# ,.,.."**Unit~Stot**.. OPP Idandfi., Numbtor 

# .oEPA Environmental Protection Agency Wuhil\qton. DC 20460 

## Registration Amendment 

### Other 

# ';:

Cottotl and Tobacco Addrus of Applieont fktefude ZIP Cod., 

### tSa.yerCropScience**1~.O._Box** 12014,2

### T.W. Aleltander Olivo Research TrianGle Park, NC 27709 

# oen"k. iff/li$ iz. "flW.ddro.ts 

## IIor 

# I'·EPA; 

# ,-

PM' Team 22 3. Ptoposod CfusiHcadon 

# o NOM 

# 0 ft,.meted



### 6. Eltpldi(ed Reveiw. In accordance with FIFRA Section 3{cIl3) /bllil. mv product Is similar or 1dentic.tlln compositionand {abaling**t~,_** EPA Reg. No.

_____________ _ 

### tNam.



## - II

## ~ Amendmlnt· Expteln below. 

# == =

."

# 1Q nnubmlnlQn in ,uponu to AoencyI.He, dOfo.l

______ _

• [] Notilicetion· e,ploinbelow. OUw·Explain b"'ow.
Explanation: U!e odd,tlon&l p"lIohl if neclI."'ry. IFor nCI,on Iend Sectlon 1t.1 REGFEE: Amendmentto Regi5trndon· RegIstration ofAlternale Conrlll'enlial Statemenls ofFonnulaICSfs). Fasl !mel!.. FEE: Nol Appllc:oblo. JUSnFICATIOH: Tho ptap!lndAiternate CSFs roneet eilheramendments 10 the CSF fer tho MUP. BlIMI 250{EPA Reg. No. 26-1-51 I).Oflho uso of nfJW MUPs forwhich**App~C<ltlOtl.slor Reg!~lrntianfAmoJ"ldrn&fl1s**  am bclngsubmilted COIlcurrll1ltly

.....ith thl:l submission. No new data required for the proposed IImendlMnlto tho subJect eod use produet

- rely on eJdstfng dala on No at tho EPA. No change mode 10 the C(lmposilion eftho end use pI"Oduct. Dlliailed llatlricallons provJdoo in IhG attachod luuor.**CO~frACT:** Daniello A. llllod1ene, 9t9/549-2711l;**eMa~;** Danlclte.Larocho1lc@bayoreropselence.com.

# I-m----------------~ 1. 

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# 11 I",;"!'" must**.~.** 

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!6. MlnMr inWhich Libel I. Allixld 10 PreQuct

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# R."**I.~er** Soluble Peckellinll 

### !- V

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### -IV No. 

### p.n eontjljn.'



# o Oln,r

, Insecticides 

### Certifk:ation .. <Lob."



# ..., . Telophon. No. 19t91549·2718

Icertify Ihet tho $l.at,monts Ihoy. mild_ on thill form "nd all .nechmtnts Ihe,.to

# 0" tNO. oceutet.end ; : I t ocknowlodgo th4t ony knowHnatly 1&1111 or mi,ll&ding .telement moy bo pUnishlbll bytine or\m9rilOlVnOnt or • ,.

# (jJ;;;~ {/tllilf 3.TI'.,

# ::~:: Registration Manager, 

## Inseclicides : 

# 14. Typ.d N"",. S.DItI



## Danielle A. Larochelle September 17. 2004 

## ;.

• tStamped)



## • •• 

## •• •



## •••• • •••• 

# , 

# .

••••

•••• • 

## •••• y
.. - ••**~- -··9--·-~-·** 

## r---
--------- ---



# c' I,Cynthia Giles-Parker,Product Manager, Team 22, Fungicide Branch, Registration Division, Office of Pesticide Programs, Office of Prevention, Pesticide and Toxic Substances, United States Environmental Protection Agency (EPA), certify that the pesticide product(s) listed below is, 

## as of the date of this letter, a 

## registered product under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, and that as such, the product(s) may be Bold and marketed in the United States of America as authorized and limited by FIFRA. A true and correct copy of the product label approved by EPA is attached to accompany this letter. Registration of this product(s) with EPA also denotes that the registrant listed below is responsible for ensuring full compliance with all laws of the United States of America, or governing jurisdiction, regarding the sale, storage and/or disposal of the product(s). Further the recipient of this letter is on notice that the status of the referenced registration and/or the accompanying label may change subsequent to the date of this letter. EPA assumes no responsibility to notify the recipient of this letter of any 

## change in the status of the registration{s) and/or the product label for the product(s) listed below. f " 

## .", EPA has issued registration numbers for the product (s) listed below to: 

## Bayer CropScience 2 T,N. 

## Alexander Drive Research _Triangle Park, NC 27709 

## EPA REGISTRATION NO. PRODUCT 

## NAME

264-418 

## Prep brand Ethephon for Cotton And Tobacco

/

. 

# /J;;> Cynthia Gi s-Parker Product Manager (PM22) Fungicide Branch Registration Division{7505C)



# 10**~------.-~**



# ,



# •



# • 11/27/02 

### 12:33 

### REG1STRATION)RTP**~** 

### 917033355596 

# 'V Bayer

# CropScience

Fax

To: From: 

# 'EPA'·

----------**---M-'-'-es"n~.-a-J-,** 

## 80:-r-oo-,.- ttn' Document Processi Desk: 

## Be Wlrriams Re ulat Affairs.

## r=:==="""-="-""''''-'.!="'t~~=~-'·····----c 

## ax: 703-305-6596

__ I 01: 

### 919-549·2425 

# 1:-"',,-,::==:-"1='------- , 

# ax: 919.549-2545 

## ; mall: Meshea,Brodie ba er 'ence.coml



### This islarequest\11M

## (~l gold 

### sealcertlfIcates of roglStralion 

### for EPA Rog. No. 

### l64-4S7

# + MOCAP lSG,

...... EPA Reg. 

## Nq, 2&+418 P"!e.

## bland Ethep/!on for 

## Cotton andTobacco, 

## Pleas. send

### them 

## to me 

## atthe following 

## address.,."

# C r --:7 

# 11J

## /Wn~ ..

## l;rf/~J - 

### /tRvk>eY Meihu Brodie 

## Sayer CropScience PO. Box 

### 12014 

## 2T.W.

# Alexa""'"Drive Reoearch Triangle Pari<. NC 27709


## TharI<yeo lor

## yourallllistance. Please caM m.**~** 

## yoo have any

## queotiOflS or concems

. Regarde,

# L.J:2~

# ~.~' Sr. Reglstnotion AUociate 

## Bayer CropSeience



# 11

## • •



# •

• UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C 20460



## Prasad Rao Aventis CropScicncc 

## 2T,W. Alexander Drive Research Triangle Park, North Carolina 27709 Subject:



## Dear Mr. ROoD. 

## Prep brand Ethcphon for Cotton and Tobacco EPA Registration No. 2644!8 Your label amendment application dated August 12. 

## 2002 OffiCE Of 

### PREVENTION, pESTICIDES AND TOXIC SUBSTANCES



## The amended labeling referred to above, submitted in connection with registration tmdcr the Federal Insecticide. Fungicide and Rodenticide Act (FIFRA). as amended is acceptable, provided thatyou comply with the f()!lo\\iing conditions.
I. 

## You must make the following changes to the labe!:



## n. 

## At every place in the label where it 

## occurs, "PREP" (without any additional prorlm:l name) or "PREP brand Ethephon" must eitherbe changcd to a nonspeciJ1c tcml 

## such as "this product" orelse changed to '\PREP brand Ethepboll for Cotton and Tobacco", the**completl.~** 

## namc ofthe subject product. "PREP" and "PREP brand Ethcphonh are also pari ofthe name ofEPA Reg. No. 264 M

### 380.


## b. In the "IF IN EYES:" subsection ofthe "FIRSTAID" section. in the second SlalCl1lc.:.'ilt add "eye" after "then continue rinsing".

c. In the Jirst sentence in the "PERSONAL PROTECTIVE EQUIPMENT (PPE)" seclion. add "made ofany walerproofmaterial" after "chemical resistant gloves".
d. In the first sentence in the secondMloMlust paragraph in the "AGRICULTURAL USE 

## REQUIREMENTS" section. change "chemical resistant gloves such as any waterproofgloves" lo "chemical resistant gloves made ofany walerproofmaterial, such as nitrile, butyl, ncoprene, or barrier laminate".



# 12

# •

• e. Move the sentence "Do 110t 

### contaminate wmer, food, or feed 

### by storagt: ordisposaL" in 

## the "STORAGE" subsection ofthe "STORAGEAND DISPOSAL" section 10

## just afit!f

## the "STORAGEAND DISPOSAL" heading, change the name ofthe "STORAGE" subsection to 

### "PESTICIDE STORAGE", andprovide appropriate statements for spills specifically (not solely spills), in this subsection.

L In the first sentence ofthe second paragraph in the "Specific Directions" column ofthe "Over-The-TopApplicaliol1" row in the "TOBACCO (FJue-Cllrcd Only)" table at the topofpage 6, Change H,••

### usingthret! nozzles (one nozzle tips over
..," to "

...using three n07.2les (one nozzle {ipover

...".



### 2. Submit one copyofyour final printed iabcliag before you release the product for shipment.

Tfthcse conditions nrc not complied with, !llt: 

### registration may be 

### subjectto cancellation in 

### accordance \\ith 

## FIFRA section 

## 6(e)< Your release for shipmentofthe product 

## bearing the amended labeling constitutes acceptanceofthese conditions,

Ifyou have any questions about this letter. please contact John Bazuin at**(703)3()5~**

### 7381 "

Sincerelyyours.

Cynthia 

### L**Giles~Parker** 

### Product Manager (22) 

### Fungicide Branch Registration Division 

### (7505C)

Attachment: Label stamped "ACCEPTED withCOMMENTS"



# 13

### TM 

# J..J;"'**-~** 

# r 4

'"

, v. 

# PREP brand 

# Ethephon FOR COTTON AND TOBACCO
For Commercial Use OrAgricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: EJi1ephon (2-ChloroethyJ) phosphonic aci(l"



### ............................. 55.4% 

### INERT INGREDIENTS: ,.."

....,.....................,,44.6% 

### *This product contains 6pounds elhepholl per gallon. 

## EPA 

## Res. No. 264-418 EPA Est. 

## No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN



# DANGER PELIGRO

Sl**u~t«lIlO** 

### t'nlierlde Ja ('liqueti'!, busqueaalgui!.'11 piHiI que- seJa (',wJiquea listed en detallt'. (If 1'ilU do nOll1lldentand 1helahd, firld wnll'Olli' to 

### explain 

### it 10)'011 in detaiL) for 

### MEDICAL And IBA.M1tQRTATIQN Emergencies!llilYCall 24 Hours A Day 1·800·334·7577 

### 1 1 The U5C 

### oj**1l1i~** 

### product lor it 

### vMiety of plant growlh regllJallOn US5 ;Ul' prote<.ted by United 

### States ;lnt! 

### foreign patents imlulhng US 

### Patent 4,240,8t9. 

### No license 15

### grarl(ed In Uk

### this prodlJtt in countries olJler**O)~n** 

### the Urtit('{1 S1atl'\. or Jor anyure not (unlempJated bi' this 1,jj)eL LiabWtv fo ate I J' Igl'n)"nt na res It

### J Je of**lhi~** 

### product**Oll~ldl'** 

### 11 f' 

### Un ted**Slate~** 

# ,**,~** 

### nmm , 

# , , 

# " rom**U~l'** 

### or $<\ L 

# , tt

## •


# .. :

# :**~** •• • •



## -- t1-JiHYE5: 

## • Hold cyeopen and rinse**~Iowlyand** 

### gehJlywitl1 water for 

## 1S-16 mi!,!ute!i. 

## • 

## •• • 

## ••• • 

## • • • Reflll.we contactlr,nses. 

### ifpre$Cllt,attcr the l1r;t Sminutf5, then rontlnue rinsing. 

### , 

## • • 

# •• 

# i. <:>11


# .", 

## • 

## • 1 i 

## • " 

## •• • IF ON 5KJN OR 

## • lakeoff(J)ntarninatedpolhing, 

# : .'

tt " 

### CLOTt4JNG: Rinse**~n**

### immediately

### will (p\enty-oJwatt'r for 15-20**mln!lte~,** 

## • • ••• 

# • <:>11 , i . . t 

## ,,,d,"" 

# :'

# .. 1';-:**.;;.;;;:~** 

### Jmml'5l1att:lyfa!! il 

### poison-ton)rQl (ente! ordoctor

### fOf treatmenl advice. 

## •

. . 

# • Do not'Induce 'iomhing 1lflles5 toJdto do $0

### by aMironcontroJ (enteror doctor. 

## • Haw:person sipa**gla~of**

### .water

### Ifable to swaJlow_


## • 

# 'moo, i 

## • For MEOlCAlEniergencies

## call 24 Hours

## A Day 

### 1-800·334-7Sn.

### "'~ 

# ,**h~u** 

### 1 " , ,d""", 

### NOTETO 

## ,.;. 

# ;:;;;,:1,;;, should

### begiven

## to 

# .**~tJ1:;** ,

, t 

# , ;,h, 

# .-- PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANSAND DOMESTIC ANIMALS CORROSIVE (,lU!eS irre\'cr\ible eyedarn.'!);c and skin hUrris HarmJuJ If

### swallowed or 

### absorkd tllrolJgh skill Do nOl get ill e)'C'S, On skin or011 clUlhlOg. 

## PERSONAL PROTEGIVE EQUIPMENT (PPE) lIpplicators and olherhant]len II1U51 we,1f ((JI'erd]Js OVI!I ,horV.ic't'I'cd shirts and short P;HltS, ,hemic,lJ rl'';islanl gJ{)I'l'S isudl as Nitrile, BUlyl, Neoprene and/or BiHfler laminalej, (heml(aJ-r('\istJnt 10otw(w pllJS '>I)(ks, 

### prolcttlve CYCI¥{'dr, chemital·r('51',t.lnt htwlgear for t:lI'erhead exposure JfrlJ (I;('nli(;llrMistant apron whl'n cleaningt.'i\III'prnelit or mixing andJoading. DisciHd (IOHling and other absorbent nlaterlals that hayc been 

### drelrched or heaviJy (olllamin;tt.;d with this products con(entrate_ 00 not**reu~l'** 

### lhem. follow**lI1<1nllla(tllrer'~ in~tru(1iom**  

### Jor cleanmglmalnlainmg Pf'F. 

### If no**~uch in~lf1rniun~**  

### tor**lVasJl<lblf'~. u~-**  

### ddergenl and hot waler Kf'r'>J ;llld**wa~JI** 

### PI'E sep.natl'lyJroll1 other lanndlY Wllell**handl('f~ U~'**  

### dosed**~yslcnIS,** 

### enrJosed cabs, Ilf dlroilll in a rrlJnnff thilt Jlltets thl' requiremcnb Jisll'd mtheWorker Prote(lion 51"nliMd \WPS) 

### tor agri(lillllral pl"iticidl'S [40 eFR 170 24fr (d) (4·6)). 

### lhe hdrllJi('r prE requit('lllfrlts In"v be

### reduced or morlilicrl

## as spe(iJied in (be\'IPS 

# 14 I

## userSafety Recommendations Users should wash hamh**brfOf!~** 

### ealing. dl**jrl~ins.** 

### (hewing gum, USillg

### tobacco or USillg

### the toile!. Users shuuld remort: clothing immediately if**pe~li(jd"** 

### gels inside. Tllen wash body thoroughly ami pul 011 

### clean clolhing Us<-rs should rcmore PPt Immediately 

### after handling !ilis prodllct**A~** 

### soon as rossl"ble, 

### wash Ifloroughly 

### and dlilnge 

### into clean dolhing.**W<l~h** 

### Ihe olll1.ide 01**glo~'es** before relilovinS. 

## ENVIRONMENTAL HAZARDS Do 

### nol apply directly to waler, or In area$ where surface waiN is prMenl ur Iu 

### Illlertidal areilS below Ihe mean high waler mark. 00 not (OnlilllllO;jle 

### waler when disposing ofequipment washwaters. 00 nol contaminate WJlcr IISed for irrigation or donltosliL**purpusc~.** 

## SPRAY DRIFT Moid spray drift Do nol aPfrlr when weallier conditions may**CilU~** 

### drift, 

### Do nOl allow !llis Jlroduct to drift on to non·target areaS. Drift Olay re\ull III illegal re>idul'S or injlllY to adjacent crops alld l'!;gelation, io We form 01 leaf }'eJlowlOg and delolialion. ro avoid lpray drift, 00 N01 

### apply <IN(Jlly whenwind speed is greillerlhan 10 mph or during periodsoffemper;1!ure inversions. Use of largerdroplel $"Ile. will also reduce sprdydrifJ. AVOIDtNG SPRAY 

### DR1H Al n-ll: AI'Pl!(1IT10N sm tS H-lf**RE~PONSJfJJU1Y**Of- mEAPPLICATOR. 

### The interaction of many eQuillnlellt'i1nd,wealher-rel<l!eJ fa(!Or5 delermine the potentiallur**~pc.1r** 

### drifL The applicator is respon;ible lOr considen'ng aJi these ladors when making**decisian~.** 

### lhe following drift**man~gemenl r;>qUlrl'nlent~**  

### musl be 

### foJlowed 10 .avoid ulf·1Mgel mUl'ernenl from .lcrial applications 10 agricultural lield {fUIII. 

# eu:se reqlliremenlSdn nor "'Pllly 10 forestry applilaliuns, public 11('<llth 

### uses or to <lpplltatinns I rsing dry forrnulaliOl15. 1. 

### The diS1<lnceof tile outer fliOSl nlJalb onlheboom rlHrst no! exceed 3/-11he lellg!!1 of the wingspOln or roWL 2. 

### Noz;:les mllst alw<lYS poinl backward parallel with !lICair SlrCilnl ,111d nl'Ver bt: poinltG dowllwards more lllan 45 

### degreC5. WilerI' stall'S hOlve IllOfe stringent regulations, lhey sholdJ 

### be**ob~r\'ed,** 

### The applicator**~hoilld** 

### be familiar With and take Into aCCOlrnt lhc Infofllli\tlon col'Cred in 1I1e**Aeri~1** 

### Dnit Redilctillil Advisory belol'o-: 

## AERIAL DRIFT REDUCTION ADVISORY [This section is**ad~isory** 

### in nature and does ilol sllperwde tile mandatorylam-I requirement5j. INFORMATION ON DROPLETSIZE fhe most elk{live way tu reduce drilt PQlenlial is 

### 10 apply large droplf'h. Ihe best driJ!**m~llagclt1ent** 

### strategy is to 

### apply the lilrgC5t droplel'.. tllat pro'iide sufficient wl'era:;e and mrnrnJ. Allplying larger droplcls**rl'-ducr~**

### drilt polt'ntial. hut will 110t prevcnt drift ifapplications are made illlprnprrJv. or undel unlal'nrable em'irorllnenlal condiliuns (Si.'e 

### Wind. T 

### emperatllfcand !Jumidity. and Temperalure tnverslons). CONTROLLING DROPlff

### SIZE Volume

- U..e 

### high flow rate Iiontes to apply the highesl wdctiul**~pray**

### volume, NoalesWilh higher rated 1101'6 prndllt(' largerdroplets. Pressure

- ()() nnt exceC'd the ooa.le**mallufactllfer"~** 

### rNomlllendcd pressures, For many nozzle types tOlVer pressllfe produce51arger droplet5. When ..-li[glll:'rIfow r,1leS arc nrcded.lile h'lgher flow r<lte n07Zles'instead ofincreasing prewre, .Imberof Iloules· lise lhe minimllm number of novll's !llafpHll'ide unifufOl

### coVl'rag~'. Nonie Orient.l!ion' Orienllng nOl.l.h '}(l 

### that the spray is releil\€(fflarallel to the ailSlream prorJuces larger droplets**th~n** 

### oUler orienfiltiom iind IS lhe recommended praClKt'. )igniflcalll deJicllioll fW1l1**hurilom~l** 

### will redure droplel Slle and**incrt'a~e** 

### drill potenliaL Nonle lype·**u~** il 

### nuaJe type :hal is dl'5igncd lor lhe- inlended i111pllcatlOlt Wilh**HlO~t** 

### nOllle lypes, uarrower spray angles prudutt' largrl uroplCh. Consider uSing low·drif!**nOllle~,** 

### soilif**~lre,lnl** 

### nonlesoriented Slrdight biltk producc 11Ie largcst drupll'band 1I1e lowest drilt. 

### BOOM LENGTH For SOme UY..' 

### pdl1erus, rt'dlrcing lhe dfeClIYC boom lellsth to I'!ss lhan 

### 314 of lile willgl/ltln or rOl0r tenglh InaI' funhcr redute drifl wilhOin R'rJIIClng**~wath** 

### width. APPliCATION !lEIGtJT 

### Application, should not be 

### made at a heighl gleatertilan10l("et aoove tile tup ofthe target pl;:lIlts llOles, a 

### greater lleight h 

### re-quired fOf arruaft**~afety.** 

### Makingapplicalions-all1le luwht heighl 

### !!Iil[ is s.afe reducdexpowre01 droplets 10**ev~poraliOIl** 

### illid wind, 

### SWATH ADJUSTMENT Wflen application, 

### Me made wlth.l wmwmd. lhe swal!1 wllille displac('{! downwind. Tilerciorc. on tlie Irp ilnd downwind 

### edges 01 !lll' lltld, the**~pplkator** 

### SllOl1ld conl)Jf'ns<lte tor this dhtllacement by**adih~llng** 

### lile path 01 the aircruit UPWilld SWilth aliju'Strll('lIt**di~tanc('** 

### sflould**inl(l'iI~l'.** 

### with Inue<lsingdrill polcillial**(lligll~1** 

### Wllld, "nailer**droJl~,** 

### etcj, 

### WIND Drift polential**i~** 

### Inwesl bctwttll WIlid \peeds 01 2

. 10 mpli Hnwe

....er. manr larlurs, il1c1uding druplel 5i7e and equiprnenl type detenlilnf" driJt potential at ilily given speed, AppticallOn 511l"lUJd ue al"OId('{! below 2rliph due to l'ariable wind direction and high inversion ptllt!ntiaL NI)Tf" local terrain L,ln 1IIIIIIence wind p.ll1clns. hery appliGlt(Jf ShOlIlri he 1:lmiliar Il·ilh 10f<ll Wind palterllS i1rld how theyJffect spraydtift 

# 15

### TEMPERATURE AND HUMIDllY Wilen making**applicalion~** 

### iu low relative humidlt)'. set up equipment to produce**targ~1** 

### droplets to compeusate lor evaporation, Droplet evaporation is mosl severewhen conditions arc both hot and rlry_ TEMPERATURE INVERSIONS Applications should not OlLur during atrmper<ltme inversion btcall5e drilt putential is high. TelOfler.1ture illversions restrict vertical air mixing, which Cil\lreS small**~uspendctl** 

### droplets to remain ill .llonccntrilted cloud, 11lis cloud can move in unpredictable diledions due to the light varialJlr. winds common during inversions, lemperaturc**inversion~ aH~**  

### dl<!fdlh.'rized 

### by**in(f<'a~i!!g tt'IUIJl~ratures** 

### wilhallitudeilnd are commonon nighls with limiled do\!d (Over and light to 110 

### wind.**nte~'** 

### hegin to tonll as the sun sets and ollcII (()Iltmue into Ihe morniu8_ TheIr presence can**~** 

### indicated by ground fog; however, iffog is not prerent, inversions can also be idelltihcd by 

### the Illovemeut of**~rnoke** 

### from a ground source or an 

### aircrall smoke generator, Smoke that la}'f-(s and**ruo'<t~** 

### laterilily in il

### concentrated (loud 

### (undr.r low wind COltditions\ indirates an inversion, while smoke that**move~** 

### upward and rapidly diSSIpates indicatesgood verlic,lt air**nli~ing.** 

### SENSITIVEAREAS I he fK'Sticide should only be applii?d whell the potential lor drill to adlilcent S("n<;ltlve**~reas** 

### (e.g. rcsidential i1feilS. hodie; 01 waier, known habitat for titreatened orendangered species, non-target**crop~)** is 

### minimal (c.g_ whenwind**I~** 

### blowingawayfrom the**>en~iti¥e** 

### areas), 

## USE PRECAUTIONS 00 

### not apply PREP'V brand Ethephlln IrIr Cotton and Tobac(o through 'Hli' I)"pe 

### 01 Ifflgatioll sj-"'telll Avoid spray drilt to nearby cropsilS this proriuct will cause ntodific,.\!Ons In pl,.nt**gro\~1h** 

### Plant inimy or relluced**yicld~** 

### will rCSlllt. l.lix only tllfamount 01**~play**

### you ('xpect to lise e;\(h rlay

. [}(J 

### not allow mixed 'iohJtiol! to staud overnight 

# • DIREGIONS FOR USE II is a violalion ofFederal law to use Ihis product in a manner inconsistent with its labeling. 

### Do not apply this productina waythat will contactworkers ocother persons, eitherdire<tly or through drift. Only protected handlers may 

### be in thearea dudng applicalion, For any requirements spe<ifkto your State orTribe, consulItbe agency**re5pon~ble** 

### fQl" pesticide regulations. Read entire label before using Ihis product 

## RAL USE REO the**thi~** 

### product only in accordance with ib labeling and witll tile worker Prolcctlon Standard, '10 

# erR part 170. TillS standard contains requirenlents lor the protectIOn of agricultural workers on larms, lorem, nurseries, and**gre~nhouses.** 

### and handlers of agricultural pe"tkides. II contains**requirem~nh** 

### for training, decontanunatiou, notilication, anrl emergency iI!>Sistance. It 

### also**contain~** 

### spenlic instructions and exceptions i the stah?ll1cltls on this f.lhel about personal prot('(1ivr eqllipillent (PPE), IlotifkatH)n to**worker~**

### and restricto:-d·entry intervals, The requiremenh in box onlyapply to USes 01 this product**th~t .1n~**  

### lovered**b~·the**

### Worker I'rotcctilm\tiliidard. 00 not enter or allow workcr entry mto treated dleas during thi"**rKtnded-e!lt~·** 

### Irlterval (REI} 

### of4fl**Jlmlr~** 

### the Rlt**I~** 

### 72 tlours in a(('as 

### where**"".~"** 

# I 

# I"""'" "s I,,, tllan 25 imhes peryear PPE required lor early entry to treated**area~** 

### tha} IS peouittcd under the WOlker I'wtectiOi'1 standilfd and thaI involves contilct witll anything that trcaled such as plant'i, wil or water is covcralls oyer**10ng·~!eL'Ved** 

### shirt <HId long p.lnts, chernic;)1 resistant glovts such as any waterproof i I**re~istant** 

### footVlear plus socks. and prote-chve eyewcill. Fm overh!'ad eXflmure, dlenl!cal-resistant headgeoaris also required. I· I ' t to**trc~ted** 

### aleal.



# 16

## STORAGE AND DISPOSAL STORAGE Do not conlamillate Wdtl.'f, 

### food, 01 

### leed Ui'**S'O(Jg~** or

### dhposal. If

### (ontainer is broken 01 contents h<lve spilled, follow all 

### prc(al1liomiudicillt'd above and deiln up 

### immediately nefOie 

### cleaning 111l, pul 011 !u!lleng;h 

### trouserS, 

### long slerved shill, plOIIXtlV('" gloves, a11d goggle<. 01 lacC'shieid Soilk np \JlIll with abwrbent media such as S<1nd. earlh or olhel sirilahle materia! ilod Ili,pow oj waSIl' al**~n** 

### Jpproved**wasl('dispo~!** 

### f,lCilily. 

### PESTfCIDED!SPOYll re51ieide wastes ,lie <I(IIlel1' llMillllous_ Implorer dlspos<J! of**e:x(e~\ rn~li(jl!e.**  

### spray mixtlrfe, Of 

### IInStllc IS a violation of h"dclallaw If these wastcs 

# I**:;;~;:;,"":;:d:~;~'P,~OSed** 

### 01 by use il(cordlng 10 labd inSlru(liofl\, 

### tOnl-a(t yon! Slille I'eslitide or Environmental (0111101 Agency or Ihe lJazardous**Wash~** the ne;;r(,5t f-I)A Rl.'g10nal office lor gUidance. DISPOSAL rjnse (or equi\'alenlj th(- emrly (o111.'lI1ler5 Theu ollel 101 lecycling or reconrlilioniHg, or pUI1(\\lre ;wd di.,pt)sc of in a sallitary landlill, or 

# 1;";;"""";'0';" ;1 allowed bystale and !ocal

### Jl1lhorilie~, by blllning. Ifcontainer is burned, slayoul flf

### ~Inoke. RETURNABLE·· REFlll.ABLE COtHAINERS
use. lelurn thr container 10 Ihe /Xlillt of**p11l(ha~** or designaled !oralioIlS, This (onlaincr must 111dy 

### be Idilled wilh PREP'" brand Etlu:phon

and Tobacco. DO NOT REUSE TIll.**CO~·HAINER** FOR ANY OTIlER PuRPOSE- Prior In relillillg, insptct Ihoroughly Inr dalnage such as 1 and damaged 01 WOrH out**threJll~** 011 dosUie dcvlces. Do nol rehll or IldllSpOrt**dam~gerl** or leaking conlaincr5. (hed;; for! i!! I' iris nOI .Ii, I I I 

## ERAL INFORMATION 

# conON A !oliar srlfay 01 PREP'¥ bland Elherhon lill cOtlOH and Tomcro will dccclerale opc11Ing o! malure ullopened COllon bolb and ellhance dclolialion which can reSUlt In f.lnlt'l h,uv('sl wilh ,1n**In(lra~rl** rl.'wwrahlc Yield Pit! 1'''' Ireatlllt'l11 on cOl\on**al!ow~** in(f!!a!>Cd cHi(Jency from a once-ovel harvest:. TOBACCO (fLUf-.CURfD): Alolial sprayof**PRII"~** brand Elherhon rllonlOh.-'s early. uniform ·yello'.\1ng" olilialUIC lobacca_**PREP'~** ledlln',; rl1f1l1!; time. allowillg 1110reefficient use ofwring balll space, and increased control over harve'il**S(h~dule<,.** SPRAY PREPARATION Add 1/2 10 

### 311 of Ihe lIo-'quirel1 aOlonnt of watel 10 Ibc spray t<ink, 51<111 agildlioll Add the reQuiled arnlluHI ull'REP'" brand Elhephon. Jnd Ihe remaining alnounl otwalfr Prep;1fr lJIily**a~** Ilwch spray soluliOiI ih(&11 

### be I1sed on the day o! mixing /)0 nOI allow spray so!otion 10**~Ianll** ovelllighL 00 nOI $pi!llhe concenlrale{j product on spray equiplllellt, or any ail plane pJrI\, ANY SPIl.L5 5110111 0 III RINSW IMMEDIATELY Wlllll'll'NTYOF WAT£R, Us(>01 il nUise lalll;;**I~** 111!ltlly I('COnlmendell rnr avoH.llllg pOSSible Wills or{OrlO"lIlr<llro 10nl1ulalion on sprayf;<.ll1ipment 0/ allY dil plalll: palls. TANK MIXTURESWITH DEFOUANTSAND INSEOICIDES 

# Ar'" brand EUu:phon is (Ompallb!e wllh 1JI.I'1, rOLEX", OlOppi. i)l()pp" UII/il'"', GiIlSt,iI"2, Ha/Vade l

- Ml'thyll'aralhioll, GUIliioll1
, and Mafalhion{

. •

### EP'~ may 

### be app!ierf in '>CqIlCHCC 01

### J~ a tank mixilire (00 NOT TANK MIX WlTIl DESIC(AN15 II' COTTON IS TO BE SPINDLE HARVESTED). tollowaU

apr!iGlb!e use precaulions <lnll rate pel <iC\t' re(Onlln(;ndalions on !abrh ollflndl1r\s 

### Jflplied as lill1k mixtures Ol in sequence wilb PREP'" bfJnd (Ihephon. In some**(,;l\C~ ~Iiglll**  Iedudlon io boll opeOing I(;,ponse has been ollser

....ell whell tank**IlIixe~** wllh defoliants were used Good agilation in**Ih~~pIJy** tank i; Nlemi,,1 Mid a I,mk Illixiule shOilld nOI hf' al!owed 10**~I<ind** wllhoot agililtiol1 for mOle Ihan 5 10 10 minllle<;. Re;\r! <illd ob..elVt' all appropri31c**I~be!** me dirt'(liolls and precalltions for Ihe delo!ialllSand inslXliddes used. NOTE: UNIJER (ERTAIN (OhDITION\ Tr\NK f.IIXTURES Of PRTP'¥ [WAND fHIEPHON WITH DESlCCANTS CON IAINING SODIUM (I-lLORATE (aULD RESULT IN nil FORMAIION 01 IIYI'O(HLOROUS AODS WIIIUI 0.'-/ HEATING Will rklll IOXIC ClllORIDf**~UMES.** 1)0 NOl MIX PRfP'" BRAND ETHfPllON Willi AMklONlliM THIOSULfr\TI \UCII lANK MIXruklS MAY RESULT IN fORklATION OF TOXIC**~UM[S** EQUIPMENT ClEANING Because 01 the acidic i1illure ollhis prolluCI, lllolollgcd**e~pnsllrt'!O** ..pray dtposil will damagc acrylic plasllCs, cNtilin pilint5, i1nd IIlel<lll, Ri use Ihoroughly wllh a detr-rgt'lit and w,l1el all exposed ,myjic p!a\IIl-lype lilalei ialS ie.g., aimall wil1dshie-ldsl, and painted**slrrlace~** wilhin an hour after**e~posure** 10 Spfilydeposils. At the end ofeach day. rinse IhofOliglil\' wiitl" del!'rge-nl Jnd walPr "II the melJI P;llis o! Iht all((dfl and the associaled spr,lY t'quipment exposed 10 Ihe spray deposlls,



# 17

. 

# ",.,,'''---------------

## conON

USE EXPEaED 

### PREP'· ONE 

### MiNiMUM SPRAY APPtJCATtON CONDITIONS 

## RAn GALLON 

### VOLUMES TIMJNG 

### PREP;REA (Gals/A}*


### P;ntsJA lnSA.1. Act" 

### G<o"d AitHH 

## PREP'" Ilot ilIld Illy80'F or 

### 1 1/3 1.0 6 

### Apply when the numlx:t 

### of BoJJ Opener"'''' liigllcr 

### matute unupenM 

### bolls 

### ;, 

# I 5uHicient In 

### produce the Dry**~nrJ** 7') to**BO~F** 

### 2 1.5 .\ III 

### 2 detted (tOp. See 

### below tor lesl 1113 2.0 ) 

### 01 boll matmity_ Treatment (001 bllt aboY(' 65¢F IInlformly opens**boJl~** 7 tu 14 0< days earlier.



### PREP'" + 

### FOtEX- ltig!1 

### soil moisture 1i3 025 

# " 10 

### 5 Apply <\ 

### to 7 

### days prior In 

### DefoHantTank 

### MixH* 

# "**PREP'~** boll tlpellilll: 

### application. 10 be used as a 

### lIig!1 tertiillY level 

### seqllential treatment with. not 

# " ill place of PREP'· boJJ op<'niog Rank cottOIl Oropp 

### High <,oil Illui;tUIC 

### 1!J 

### 0.25 24 10 

### 1 Apply ·1 In 

### 7 dal'S prior In 

### OetoJiantTank Mix

...... 

# "' PI/FP'" boll 

### opening ItiSh tertiJity 

### level 

### appliGltioo. To be 

### used as it 

### 5.equf'ntial trl'i.ltlnent with, not 

# " ill place of**PREP'~** 

### boll openillg 

# , , Pre-Conditioner I" 

### tlot, dl)" aboV{' ROOF 

### 213 0.5 12 

### Apply <1 

### to 7 days prior 

# " Defolialion Caul, abovt65'F 1ir'3 

### to 

# " to 

### 2 

### ddoJianl Eohances top (lOP 

### defoliation reducillg 

# " deterioration oJ 

### bottom (top R.lllk COttOIl 

# I,,,d I ;

.. For best 

### pelfolmallce, by glouml or illr ,1pplicatloll,**cJIOO~** 

### cqulplnelll and sprayvnlilm/.'; that**wllIlll~1J11!** 

### unilorm (overage 01 

### foliage and bolls.

,..,. Prelreatment With Defoliants Priorto PREP" brand Ethephon 

### Bo!! OpeningTreatmenl: II the cotton**i~** 

### ovelly rankor layiog down in the middles and good**~prJy** 

### col'erage 01 

### the bolls with**rRLI"~** 

### is dillicult, a pr!'tlealrnenl with defoliallts. will be uselul to improve 

### boll coverage- with**I'tlt-P'~.** Usc 

### dosage hUes of**PRrp'~** 

### INOIOIliellunJ 101 boll ope'ning. Read Jlld**I)tJ~el\'e** 

### dll appropriate label use directions and ptelOlutiolls 101 

### tilt: de/oliant used

.

...Can 

### use up to lull label hue

### lor each prodllct,

••In (alilOlniil ilod AliZOlla liSt 

### avnlume oiliu

### Ie\~ ttlJ.1I S

### gallons fif'r Mrt' for aefl,,1 "pphr.lllolI;,



### BoH Mflturity A

### boJJ is mallrre when II**i~** 

### too hald to be deot('d whf'n sqllccn'd bdwt'co tllllmh ,1nd fingNs, ton hMd tn he 'iJiced with a**~,Jlarp** 

### knife, and wilen the seed (oat becoilles ligllt brown in cnlor 

### Use limitations
Do

### not**e:xc~d** 

### a maximlltn of 2 0 

### 111 l!llicplloll ,)(\1';(' 

### ingrcdiellt per a{r" per

### yeal Hllougll coillbiuc(]or retleated 11Si:$01 

### any ethephon product:;, Boll Opening: 00 

### not tillik mix**PREP'~** 

### lirilnd tthepfloll willi iI 

### dt'5lccant il the cottoo is to hI'**~pindlr** 

### h;HYE'..te(L Pre-Conditinn 101 

### lJelliliatioll: 00 

### not tank 

### mix**PREP'~** 

### hrilnd ftliepllon with OC,lCGllltS ulllcss plant dC'Siccatioo is tequired. 00 

### not mea 

### defoli"nl belore the-It'; is**~llffirient m~tule**  

### Iltl0PClll"l.l !Julb to plodllc

.... tile de,ired 'Iiehl (;ee 

### henerdl IIllonllJliol1 'it'(liOiI on how 10 

### tC'St lorboll millur]t)'_ DO NOT APPLY**PREP'~** 

### BRMiO rlttt'PItON It 

### tlAIN IS EXPECTED WI1It1N GtlOH.:\ 

### Rillfll;)1I witliill fi**hnll~** 

### of ;)pplfcafion mal' reduce plOduct perlormaoc('.
00 

### not plaltttHlother (topWithin 30

### dar) 

### alter tle:ltmrllL Siliall grillOS plamed f:,\rher thim t month Of 

### IOtercropped with the cotton (fOP 10 

### whic11**PREP'~** 

### will be applied Olay 

### only be me.] 

### as W\'t.!l ClOpS aod 01.1)' 

### not be IhHVf'\lerl lor load or frKf I'Rrp'· 

### may cause yellowlng alld grm-'Itli inhibition 01 

### treated slllall Y,fillll}_ WHEN TO 

### HARVESTCOTTON 

### Do Ilot harvest UlttOl1 SOOlterthan 7days allCt a IIratment with**t't(I=f"~** 

### brallu Ethel)lloll, Observe the Ireated crop and hJfVt'l.t**\~hl?fI** 

### OptUlllln\ bell opening**hi1~** 

### ht'en learhel!, tllO**eall~** 

### 1i;>T'ie.t might ledute the futl advantage Qj 

### thf.' lIe&tlllt'lit <llId tuo I<ltc a IIJlvest may I('sult in rffitJ{t'f1 Qllilhty alld**lo\~** 

### 01 lint wllich wilililnp Imlll tilt: plant 

# 18**~--------------------~--~~-~~~ ~** 

# . TOBACCO Flup-r",prl Only)

r. 

### PREP'"

## ~-~-"Y, 

## w"fi, 

# , ";;,:-

t 1/3 

### SO Use drbp nozlles, (iroose tG (lr OC 

### ,pray tips designed to apply 50·60 gpJ at 3)-40 

### Applkation**p~i ~rrtl**  

# " tractor \peed of 

### B mph. 

### U" :2**110lZle~** per row; olle on each side of the row dropp('(/ Irrl\' eoough In direct tire spray to the**Il'ave~** to he ripened and harvested, 

### Thorough spray coverJge is csselltial. With a 

### directed spray, be \Urc 

### to harvest all**Icave~** 

### with 20% or mOle



# " ,**u,,'~ '"~~**  lop t1!3 22,13 <0 

### Treal only wlien Iraves rernailting 

### on the stalk dte OIilture To**en~lIre** remaining


# , leaves are mature,**te~t** 

### \pray several tubacfO plants as desuilreu 

### Hodef the section "Proper Time of Tredtntent." lise the lower rak in a normally mature (fOP when t'xrcriCf1CC 

### indiciltes thallOiniOlUIO ripening inducement**i~** required. Use the higher 

### r<lle when the crop is heavy and**lIa~** 

### a tendency to be rnore fank or when tempe-ratures 

### are lower than normal. Always test spray to determirre- ifthe tobacco is rlliltJlle enouglr t(l**re~pond** 10 

### Ireatmentwitlr PRfI'''' Apply ovcHhe-tup PRH"" spray as a 

### line mist**u~irr&** 

### three nonks (one- lIonl!.' trps O'ier the CeirtN 01 

### the plant. and one un eacll 

### side} so 

### all leavcs are covered thnrollghly, similar 10 

### I 

# , Ir"nero nl sy,te-mic '>trckN (ontrol agents. Use 

# I, ,140 '0GO

# p;, USE LIMITATIONS Ou not apply**PRrr'~** 

### brand Eth!.'phon to intmalure lei\v('S a\tlli, (an rM1l1t in**un~trsf~ctory**

### (olnring. weight loss and reduced leal quality. 00 

### not allow the (fOP t(l over ripen in the lidr/ alter Ir;iltg**PRfP'~** 

### brarrd tthr.pllOn,**~ince-** 

### this may**cau~('** 

### .,nlue reduction in yield and qualrty, 

### Do not treat befure- antiLipate<.l major**~torm** 

### which lOuld prevent I raNest and re\ul! In crop**lo~~.** 00 NOl 

### AI'PlY**PREP'~** BRAND 

### HHEPttON tF fV\IN 

### tS EXI'EGW WITtIiN 6 HOURS, 

### fulinl.)11 wittrin 6**hour~** 

### of appli(ation may reduce product perlormimec. 00

### not uS/! PRfP'" br(lnd Ethephon with**additive~** 

### othertlr,ln rewf1\mend('(! OH thIS label. 00 

### not plantanother crop within 30 

### days aft('f tr('JlmerrL Do 

### not e;;(Cftla 

### rrtaxnnurn 01 

### Jibsetlrcpllon ,1Cflve ingledient trer ,>.cre pN year throngh repeated use,

### ul arry e-t1lephon**prudud~.** 

### APPLICATION TIMING Suuessful**r~ults** 

### witlr**PI!EP'~** 

### brand Etheplron GIll for tre-atmerrt r.i1enlcw.'eo, are matwe, nnt overly rank green wlren sprayed. lu easily deterrnrrle tire proper trealment tilhins Jud the uumher of 

### leil'lt:s per 

### stJlk re-ady for hilrves\. test**~pray** 

### :;cveml**plant~** in 

### m()1e than 0111' 

### IO{iJtion in ("ilCir field ilnd observe the re.ponse. Matnre**leav{'~** 

### will beRin to

### ycllow irr 24 to 72 Im,urs,**Te~t** 

### leaW'\ tlrat fail to yellow rn 72 huurs Me not mature and art' not readi' 

# l1li1 PRfl"M 

### tre,ltmen!. W.lit aIf'll.> rJays 

### to ptrm'll lurthN 113frrrill maturrng. tht'H**rn~k!.'**

### anolher test**~pray** 

### or "InatlJr'lty" cherk.

.. avoid quality 10\5 

### and ur

### po,~ible- leal drop,

### Irarvc~t any yellowed

### le~ve~ prior to applir;}tiurr

### tN~ 10WN 

### rates under rnost cunditiom. limit Uk 

### of higher**rate~**

### to (001 

### ihdow 65f

### ilt tile time of 

### !reiltrrrt;ut)**~Iow** 

### rqrCtilng**lbtlditiorr~_** 

### Wiren you !rave confirmed the**de~ired** 

### rrumilfr**(Jlleavl'~** 

### per plant that WIll tol!)r, yorr edH rll!lerwiH<" til(' r!limber nl au", ro treat iu Older to fill tire harn. Prepare your tC'St spr,ll' by ulixillg (Jrrl'**tea~poon** 01 PR[\,'v 

### brand Ethf'ldron nr 1quart 01 

### water. Spray each le\t pl,lnt wrth alJoul t UL 

### ofthis mlxturt'. covering alileav{'5 witlr a !rne mist PREP'" will not tulor rmrnatlH(' 5pmyed**Il'a~e~_**



# 19

# r

•• WHEN TO HARVEST An filature, spril\'cd [e<lves win lregin 

### 10 (olur within 

### 24 \0 i2 

### hllurs after**PREP'~** brand 

### Ethepholl <lfrpli(,llion. 

### The )'el[owing 

### protl:$$ is weat/ler dt'penden!; (001 weather will d('lay. 

### while hUI, SUliny

### w(';jIlIN (an**~p('ed** 

### IIIrthe process. f-lafY('Sltf('<l\eTI IOMC(t)whc[I [caw'S have reJthed fhe desired wlor intenSity, Ildr.'est can tOmmCf1{C 48 hours '111C'r**I'Rr!"~** brand f)lIcpllull ;Jppli(dIIOlf. 10 IlclNlnine holrYeSllimiliS Jml avoid qUillity loss ur ledl drop, clo-.ely monitor tre<lled crop and weather (oDditions 

### CURING PREP'" BRAND ETttEP/lON TREATED TOBACCO 

### Curing procedures ilrc ii, mirth ;111 

### art as a science dnd each (Ufe nlUst 

### be iudgetl on the basis o[ tobacco conditiun, interval betv.'een trealmenl and harvest, weather and type 01 (uring t<I(ility helole pre>(IIPtion tempcrdture and**~enfilillion** 

### s<hedubGin be**e~tablished.** 

### fo obtain milximum quality, (are must be taken to obwrve and (ootrol the (IInng protes, dosely, !'Specially(hlrillg the Idte "(oloring" and early "drying" stages01 the leal.**PREP'~** 

### ur,md tlhepllon treated tubatto will have**~tdrtcd** 

### the (l)loring fITQ(ess when**hiuve~ted,** 

### reducing the time required in the coloring phase 01 (uring. Treated tobacco should be dfled**la~ter** 

### illohacco leaves;ue greell Of wntalll some greelt when harvested, it 

### may be necessary 10 (olor diem lor a lew hOllrs. tl the len'lM: arc complelely yellow. temperature and 'fentil,1tion Iflust be**adi!l~ted** In 

### il Illilflner to dry the lobacco**a~** 

### fast as**po~~blc** 

### witlrollt scalding. Once Ih(' leal i, dried (J!4 dryi. ylln should lollul\' nOfilial piocelilfr,,", lor ((Iring. Sinre**PllfP\~** 

### 1(eated leave, (tlfe laster, treated alld Ilfitreated leaves should not be lUred together in the '><:Ime biJrn 

### IMPORTANT: READ BEFORE USE Read Ihe entire Dire(tlOos lor**U~C,** 

### Conriitlom, Oisctilinler of Warr<lnlics ,md IimifallOn> 01 Liability bl'lore using this product. If 

### terms are nut aW',-ptablc, return the1lnopcnet.i prodlltl contalfl('r at onr.'!

. •**u~ing** 

### tills prodlrC!, Ils('r UI boyer**ilW~plS** 

### the Ifillowing Conrlitiolls, fMdalmel ofWarr;rnties and Limit."Jtions of liilUility. WlNDITIONS: 1h('rlir('(tiom lor IN: ollhisprndllC! arf' !Jeli('ved to be adeqllale ,mel should be lollowed carefull,'. However, itis impos,ible to t'hminate all risks**a~~ci,:lIed** 

### with Iht' use 011his plOdlfct (rop milff)" ioelle(tivelle>s or other linintended (OllscCjllences may result utXau.se ofsuch laClors as weather conditions. prescn(e [II ollwr malerials, or tile IrlillWer of use I)r ilpplic<wt!ll, an 01 whidl are be)'olld tht' control 01 Aventis CropScience. All such risks shan be ils.5umed by the user or buyt'1- DISCLAIMER OF WARRANTIES: ,\VENTIS (ROI'5(11 Net 

### MAKES NO OIHlRWARRANTII \ EXPR[:.5 01{ IMl'lIW, Ot· MflKHANTADlllTY OR Of**mN~~S** 

### toR II PARTICUL-\R PURPOSE OR onIERWISf, THAT [X

### tEND Bt

### YOr.1) 11IE51ATfMENIS MAD[ 0'\1 (HtS tADEL No agent 01 Avt!ntls CropSCience**i~** 

### allthorized to Irtake any vlarranties be)·olld thoSf' (ontaint'tl heJeili or to modify the warranties lOnlained herern, AVt NTIS CROI>S(tEN(f DISCLAIMS ANY tlABILITY WIi.>\lSOEVER FOR 

### SI'EmL II">ClO!:NTAL OR CONS[QU[Nl tM DAMAG!:S RfSUI tlNG fROM TttE liSE OR HANDliNG 

### orTtliS PRODUCT. LIMITATIONS OF LIABILITY: THE tX(lUSIV[ RfMEDY OF IHi US[I( OR BUYER tOR ,\NYAND AlltoS51:S. INJURIESOR DAlvlAGES RlSU!TING FROM TltE**U~E** 

### OR HANDUNG OF TillS PRODUCT, WH[THI RtN CONTRACT, WARR,-\NTY, TORT, NfC,UGU-.'C[, STRICT lIABtliTY OR OTHERWtSE, SHAll r-iOT EXCEED IHr. PURCHASE PRtCE PAID, OR1\1 AVCNTI!> CRDPS(tENCf'$ ELECTiON, TIll R[PtArEf...1INT or PRODUCT 

# •

IDtFalld (,uthioll are registered trddelnarb ot Bdy\'f AG, (,trroany 10ropp <lnd Ginstar are rrgbterrd tradeillarks ami Ultra is atraoem;lfk 01Agr!\"0 JHalYildc 

### is aregistered trddemark cf

### Uniroyal Cumpally. 4Malathion is a trademilrk 01 Ameri(an CyanJmid Coropall)'

Aventis (ropSdeoce P.O. Box 12D14, 2T.W. Alexander Drive Research Triangle Park. North Ca(olina 27709 I'RFt> is the**trddemar~** 

### ulilleAvellti, Group, tOU';': is a wgiSIt:'fet/ trademark 01 theAvellti, Group PR[I'''' brand Ethephnn for (oUon and TouJ(w {PtNOINGJSublnlf\rd 7/17/02



# 20I 

# , TM



# PREP brand 

# Ethephon FOR COTTON AND TOBACCO

For Commercial Use OrAgricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: Et!lcpllon (2-Chloroethvl) phmphoni( 

### ilcid'" 

### INERT IN6REDIENTS:

_ ......"

.. ,. ,....... ,........ 44.6% 

### "'litis prodtlO 

### (ontain<. 6 POtlllds elflcpilofl 

### per gJllolL 

## EPA Reg. No. 264-418 EPA Est. No. 264-PA-01 

# KEEP OUT OF REACH OF CHILDREN



# DANGER PELIGRO**~ 11~I('d**  110 ("lltltlllle 1,1**etj41~t,),** hll;queil illguifll P;-1I<l (111e se la**~xpljque** <lllstcd eo del",II",. III )'OU do flOt IIfldmtilfld tilt' I,lbel. lind**~(lmO:llne** to 

### eXrl,lin 

### it to you in delail ) 

### for**~'£Q!'QL**

### And LRANSPORTATION Emergencies Q.NlY 

### (al! 24 Hours ADay 

### 1-aO()..334·7577

use 01 Illis proriliO lor a**~'Jnely** 01 plJllt gOl

....11I legll!atioll**us~** Me pfrJlt'ttC{1 IIV United Stille,> dod loreign**lIalelll~** illdudillg V.s. Patcnt-t,2'IO,S19, NO li{('rISt' is**gr<lIl1~rllu** U'ie IIlis plOrllicl ill (01lItiril'5 olher Ihanlh(' Uniled Sialc, 01 for**an~'** 11\(' filii crlntl'mplall'rl hy Ihl\ I

..hel I["bilil}, {(If palenI illtnflgefllenl Inai'result frOll1**II~** or 'WI('**olllll~** produetOllbi(lf' IIIe Uniled Slal(-,.



### S 

# ",tk5 !<V""'/'**~Ccl** 

# ;-F-,

• 

## • 

# .' · 

# . 

# .. •• 

## • ••• • 

## • • 

# ·Per- 

# r**R·Nct-~ ~** 

lhis 

## PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS (ORROI,IV(. (au'\ts Irrl"'.'l'(lii)lr eye dilmage alld skilliJOIII$. 11;Jr(lIful il**swallVl~rd** nr ,1\),Olbcillliwlfgli**~Iall** Do nO! get in ('\"1'S. 011 ,\(11) or 011 dodlillg. 

## PERSONAL PROTEGIVEEQUIPMENT(PPE) ",,-.l<- 

## of**~~y w,j-"",~~of>**  'J {,**~...j-~,~** ,\pplitalors

..lid olllt:r h,lIldlers**mll~1** WI:,'lf (over,ills over**~j(oll·skn('d** $lii[l<, ;lIld ,lion pallts, (/1('1111(;11**rf'~"lanl** gloves Isuch as Nllrile, Hillyl, Neojln.'lIe and/or B<lujf'[ lamlliat('). (hl'llIlcal·reml<lnl footwear pillS $nd.s, prol(,{liveerelVl'ar,**{h(,flll[al·r\'~i51<iflt** 

### lIeadgl'ar lor QVl'rllI'al1 expOiUH' .1lld (hem'lealn",istant aproll whell cleilililig eqllipment or mixing and !oJd!ng Ois(dru dothill); lind Oilier absorbellt Ilialerials Illill hasc bel'li drClirhed or lieavily lOlltanlill<lle<il'lltll Ihis plOrlUCh tOflccntrali:' 1)0 not**rell~** llieln, Follow**milllilladllrel'~** IIlstl**urllf)f1~** lordl"ililllIgim.ljnl,linlll}; ?I'r II 00 \1 Kh**III~trll(** lions lor**\>"as!iabk~.** IISI'" delerg"lIt ilfld hot ""<lIN Keep <lnd**lVd~1i** PPE ':>I'parately from other I

..lllldl)' Wht'nIMndlt'ls 1I'>t clo«>tl**\~.,tenl\,** fndosed railS. m ')Ir(ralt Ill" UI<lnIiN that IlIeCI$llic reqlllftrllenlS**Ii~ted** In til!! WOI/.;Cf Pllltet.li,.lIl**~tamlillrl** (WI'S) for ilgrinrllliralll<!SlKidl's

### [·W (HI. )702-10 (ill 

### (Hi.\). llir hJfldlcr I'PE r('qllirunef1t5 mJv he reduc('d or nloddled**J~** spetilied in Ille WI'S 

# 21 

# y

.._-----------

## •
UserSafety Recommendations Uscn s/loilid waS!1 hands 

### before cillillX. drinking. <-heY"ing 

### gUill, using I(1Uil(fO 

### or IJsing 

### the 

### toileL Vwr\ shOilld 1('lnuve (iutiling**illllll~idt{'ly** 

### il pesticide gl'\\ Imide. 1111'11 wash body 1I1orollghJy

### and put 011 <.1('<11] <lotilillg.**U~('fS** ,hould remuve l'pr immedi,ll('ly i1Jter hitmlling**tlll~** Plol!lI(.1. ,\\ SUOII**a$llo~SlbJe, \vil~1l1hOlouglil~'**  imd rJlaoge inlu dt'.lll cluthing WJ\h the IJut,lr!c oj**glo~"'>**helm

..**rf'mU~l!lg.** 

## ENVIRONMENTAL HAZARDS
Du nol J[lply directly to wilt("r, lJr 10**Jr~il\** wiwlr $1111.)(' Willer h fuewllt or to inl('rtirl,lj <11<'01, helow the loe,m higll Wdter Illilrk Do not LQrltolminille \','"Iel**\~Jlell** disposing oj equiplllenl Vi,gllw<lters. Do not (Onlalllill;Jt(' w;1Iel IIY'{\ lur Iffigatioll or rlollw,ti( !ltlqMJ><',. 

## SPRAY DRIFT**i\~'oid** spray dnlL Uo not**<lfJ[Jl~** wlielllVeilUIl,r colldltllln5 mill' «IU\.C drilL Do uot allow this prcrllltt to drill 1m to rtlln·targel ,HeJ$ Dllll may result in iUcgal**residue~** or illiliry tn <Illi,ltellt UOP\ alld**~-rgetation,** III**thl~** lorrn 01 leal yelluwing ilnrJ ddoli,11illll, 10 aVrJilJ spr,lY doll. 00 NOI appl)' <lellilJiy when willd**sp~~d** is gredtel Illan 

### to nlph orlillring 1l('1iods ul ternperatllre In.t'mom. U<.e-

### oJ larger dropkt**~i7e** 1'0111 "boreUlite**~pr~~'**drift. AVOIDING 'lPRAY DRIfT AllllfI\l't"ll(!\TlON 

## stfr IS WE I{E'lpO"I'lllllltfY Ot HH Al'PLKAlOR_ 1 he interaction ul 1Il,IIly ('{jlliplnellhlnd v.t'dtheHt'lolteilla(tors determine lhe potentl<11 lor**~rilV** t!rilt llll! Jppli(iltor h responsihle IIlI runsrrleriog JII lhe.e**tJ(\OI~** wbell milKlllg ti..ci\ions rhe lollowing dolt Inan,lgernent reljllirernents musl be 10110'1.'('11 to JHIIII iJll lJrgd 1110l'erlll"111 110m aelial <lppliUlIiolis to Jgrilullural hl'ld OUj1\, .dIII/il.leY.:'**r('qu~'renwllts** du not apply tu lorestry ,rppir(,ltrolls, pllbli(**IlfdItIIU$.e'~,or** to irpplicatiulI, lISi.n1\ dlY lorlllillatiolls,

• TII("ulst"nt/.' 01 tile ollkr must nlJlllcs 1)11 the bUNII IfllJSt Illlt e;o:cct'd 1,4 tIll' ienglll 

### of tlrewllIg\p<lll ur lolllr_ 2 NoalM I11llst**ah~<I~)** pIlint Thlckw,lnl p,llillid Volt!! lIle ilir ,1I('anl 

### ami ne\,1'( 11(' pointed**drJI~m~ilrtJs** nlOre tllall 45 Ilegrces_ Where stales**h~vl'** 1110re striogent rcglliations,**th~'** IhoulJ be oihrr.'i'tl rhe ,1pplkatnr '>llould h(" ianilliar willi <lnt! tdk 11110 ,'t(ounl the Inlorillatiun**(OY(~I("I)** illtire "elial Drilt Reductloll ,\d\'r50I)' Ilelow. 

## AERIAL DRIFT REDUCTION ADVISORY [Tlli\ s,e(tion isildYIWty ill**n~tlJrr** ,Iod does uol ,upersede tire rndlUJatory !,Jbd rcqullcrucllbj. INfORMATION ON DROPLET StZE 1I1e rno,t cJJrttivt' \\"lY to ICUU(C dlill vOlcnlrall) h! apply largf**ur{)pl('t~** Tile be\t dlilt Illiloilgement**strJ.leg~** i, tu appl)' the klrgesl droplets lh:Jt provide suJJiricnt (Overa}\e<rlld cootroL ApoP!Ylllg lalger droplet) relllJu."" drift powillial, but \'>iJJ nut prevent dlilt il ,lllpliutiulis**;lIi~** Qlade ilnplopt'rJy, ur unlier fIIlhrvorable eO\1ronrtlentill conul1ri)ns (Sel' wilirL lCIIlIJI.'rJlureilild llumidlly. illid ferlljJ('ratlile lnv("r'iion\j , CONTROLliNG DRDPLfT SIZE Volunl{" Use high 1I0w r,lIe lIu7.des to apply**tll~** illglle\t prattleJI SJlI.)), HJIIJme NmAc\with highcr I,lled IIml'\ prorJ,utelalgerdro[lleh. I'rC'>sule • Do not exr:cfd tire nnole IIldlllllaOlirer's ICU)!I1/l!endHi ilre%Urcs FlJr 111,111',' nUl/Ie t"(lle'>**hrWI~r** pleSSllre prodw,<":S larger dropll!h, Wilen Iligher tlowrales i'I/(' rtN:deri, rl}{' Iligher**JlOI~** rJte 1111ll!/.'\instead 01 irICrtminit**llr(,~sllr('.** ember01 nunlc\· Use the lIlilillhlJnl nllmber 01 nullleL lhM

## provid~ \IIlriufln (Overage, .' ,

Nook01ientilliun •Odenl'lng**n07l1~** St; tllal lhe**~pra\'** IS released**p~rirUcJ** 10 Ule Jirs\re;-Hn ploduCt's IJrgl'r dloplets tllan allicr orientaliolls Jnd i\ tll(" r('wmnltlldeu priJcti('**~il!llrikiint** ddlenrnn (uolm hOlil1lllt,ll \\'ill w(j(Ke dloplet weand ioueascllriJt fXltentiJI.**~unle** Yype· use " lIo111e 1)'fH' lir"t rS rlesignl'd lor the ilmndNj ,'Prlicdt!!)!l Wltll II1ml nUllle tV[-ll'S, narruwer sprJ), angles proullct:' largtr droplets (ollsider Iising luw·rJrrJ**In()lll('~.** '>ollu \tledll!**1I0lLle~** DrielHed**~t[,jigllt** had; proflu«(' lIlC IJrgcst dlopl!"h and tilt' luwcst dlill. BOOM UNGTH For Wille use patli'rIl5, rftillLIlIg ttle f'1I"OIvt: boum length 10 leIS lhan 3}4 01 lite**l\'illg~PJII** or rotl)l 1r1l£lh IllilV IUlth('r l<'dllc(' drill wiliiont retillLing swalh \

...·idth. APPLICATION HEIGllT .o\PPlicatiolls slluulu not be milrlc ,Itd 11l'I1\hl gre"ltr thiJn 10 Iet:t JIJOH' the lop (II the tJlgel plants unless J gredtel helgln**I~** rerplired fllr aimillt "-<lIe\\, M,ddng aprli(iltiolls at the luwest hClg!111hill I, <,cife reduces expO\\III' ,11 dropl!"ts 10 E\'<Ipt'lr,)tioll Jnd willd_ ' SWATH ADJUSTMENT Wilen**apprlf,1tioll~** M!" I11Jril' witlr ,I**OO~I~'lIlrJ.** Hie 5\1'a{1r**I~rll** h(' dl\[1l:lreu downwilld.**lllt'leloll~.** ull tilt' IJr ,lnrJ Ilol'tnwind edges 01 lht Helrl, tile applil,dtlJr**~hrl!llu** \OUIIWI1",'to: lur**thi~** Ilrwl;rCf'llWnl by ,1d[lrSting tl1l' p,lth of lhl' airuall IJPWlllrJ Sw,lth adju\tll1t'nt dlstall(e ,IIOuhllll(H'aY.::. Witil inaeasillgdrill jlOl(,!ltiJI 1.1liglll:rWilld, "lllalier drops. etr.) " WINO Dlift pnt('lItfill is lnw{"\t h(,h\'(-cn winrl \pet!(h 01 2

. 10 mph llllIU'VI':'f< IIMOy f,l(\{)(\, !Il(\lldUIB droplet Sill.' dnd L'ijlJlplnerlt f\'pe ul'tenl1ille dlill poti.:ntial at any Riven sfX:!.'d, .>\pph(atinrl**~hmllu** Il\' .l\'oldro below 

### 2. lTllib rloe til v,JIIJhlc 'hind IlirN.tion iind Iligll illn'rsion potelltlal N011-' total terrain Gill inUucll(l:winrl p<ltlenlS E;-ery ,Wp\rCiltor sl!Orlhl 

### bto 1<111111"11 wi;-h !u(al wind patterll,JmI how lhey JJlect srllay drift, 

# 22

### TEMPERATURE AND HUMIDITY WIIt'llllIaking**a/1J1licalion~** 

### il1ln1'; rd,lIive hurllidlly, sel up equiplIl(.'n1 10 product' IJrgt'!**dropl~g** 

### 10 COlilperlSJle lor l'\·,ll){Jl,llion. Oroplel t'vJpor,llI011**i~ Inn~1** **sev~re** 

### \'Illcn**(Onllilinn~**

### arc bnl11 1101 illlil Ihy TEMPERATURE INVERS1DNS**Applicajion~ ~llolllri**  

### nol occur ullring" leiliperdlure invenioll ba;]usr Uilit palelllial is hlgll lcmpCldlur\'**il1\'cr~lons** 

### 1 eWilt vt'rticJI air olixlllg.**l~llItll** 

### r<lUses :.mall**sll~pcl1uCd** 

### dlOrielS 10 It'm;)in ill ,1 lOncelllr;11ed clUild. This dllud riln move ill uflprf!{/iclaole Ilir('(11U1I) uuC' to 

### Ihe Ilghl variable**wind~** 

### conlOiOl1 dllrillg**jrl'icr~ions.** 

### TC[llller'l10r(· invt"r\ion\are (iIJrdCleriLcd**o~ in((('J~ing** 

### lemJlerillurts wilh al11111ue ailU Me cnnllnOil on IllShls willIlimilell rloud cover and lighllo 110 Willd, fhey bcgil110 lorm as llit 11111 

### seh and often (fJ111ifl1JC 11110 Ihe mornlog. Their pr('Y!flCC rilll be indi(')H'd by ground log, IlOwcver, il foa is IlOt preWlll. il1w(siOils (all al$O oe irlelilirll>d hi' lhe 1110\'(:I1)('rll 01 Ill1nl:C fl0ill" gl()und wurre or <111 aircral1 smoke gtnrr<lI01 5ulOke IhJl lai'ersilll(ll11oVCS IJ1Naily ill " ((i1l1;t!lllr,lled rlIIIIU (IIndrr low WiIiU rnlluiliol15! illdil:(Jles Jil**il1\'N~iol1,** 

### while Imok(' 111.11 nlOVe'S upward Jnd r,lllidli'**llissipdle~ in(lic;lIc~**  

### goorl H:r1ilal air nuxill!:!. SENSITIVEAREAS 1 lie l}('sliliue 5liol11d (lilly 

### be applied 1\'11<:'1]**lh~** 

### pOlentlal k,r (/1ifll0 ,)djacenl sellslli..-!! Me'}s (e.g. residellll,ll**drea~,** 

### bullies III watel. kllowllildllilJl lor**IlueJl~l1t'd** 

### Ilr emJangerel1**~PetiC5.** 

### fl0I1-I;l1g('1**1I0p~)** 

### il 1Illllirna\ [e.g, wilen wiml is blowillg**,1\~ay** 

### 1101111he sellsilive**ilrf~as1.** 

## USE PRECAUTIONS Do no! JPply PRFP'" IIri!ml Ethepllull for (oHoll ;Hld Tuoa((uthmugh Jnv Iype 01 ifflt\<lliull s'r,ICIll. Avoid**~pray** 

### drilt 10 Ileillby**crop~** 

### ,)S lhis ploollrl will C<)II\.C mmjilil.allolls il]I11al11**~rm~lh,** 

### Planl injl1ryor redllted Yield,> will resulL 1>lix only lhe ,lmOllill 01 ,prav**~Oll** 

### ('xpccllo IIW e<illl day 001101 ililow mixed solul11l1110 \Idllrl o\'{'rlliRhl, 

# • DIRECTIONS FOR USE It isa violation ofFederal law 10**u~** 

### lhis producl in a manner inconsistent wilh its labeling, Do not apply lhis ptoductin a way lhatwill contact workers atollterpc(sons, either diredly orth(ough drill. Only prot&led handle(s may be in th(' area duting application. Forany requirements specific 10 your Stale orTdbe, consult the agency responsible for peslicide regulations.. Read entire label bcfole using this product.

Ule Ihis producl only in ,p'-(I1rUd01ewith ils IJbf'lilig ;lIIU**\~ilh** 

### Ille Worker Proleclil1l1 St.1l1daru, ·tl1 CFR pan 170 Thi\ SI,lllrlilnl cOlll<1in\**rt'i\lIirCmelll~** 

### lor Ihe proluliofl 01 agliculll1ral work{'f, ilil 

### fanllS. 10(eslS, lIufs('ries, and \tr('t'lihOIl*S, ;;nd**lIiI01I1.;r~** 

### 0\ agriwltural**!leslicide~,** 

### It**cnllla,"~** 

### II lor 1Iililliog, dewnlalllinallOn, nOlill(Jllon, ;]IIU ('IIiCIgeIlC},**,:I~'ii~lancf'.** 

### 11 Jlw WllIalllS**~pe(ifi( 1Il~III1ClioI11**  

### ,llld exceplions pertililling 10 I 11 (111**111I~** 

### label aboul perwnillllroll,{live P,{juitlment (I'Pl). 

### nOli!lcalKill lIJ 

### worker,> ,1110 restll(,I('/I'elllIY ililervdls TIl{'**reqllircmelll~** 

### ill 11(1'0; onlyapply 101M'S 011**hi~** 

### PIOduLt lh,H <lrt' covererl by 111eWlJrh'r Prolectlun Slal1l11rri, nol enler or allow**~~OIkcr** 

### efllry in!n IltJled ilrc,1S durifl\t**Ih~** 

### 11?511iCh'fi·eotr'y inler";lll.RI I) 

### \,1 'IB 

### hl)IIIS. fhe REI**!~** 

### 7 2**ht!{If~** 

### III JredS wllere

# """g'I I I is Ics'>lhal125 inchK per \".'Jr 

### (equirNilor early el]lry 10

### lr~alt"{1**arl'iI~ 1I1dll~**  11l'll1lil1t'd llnder the Workcr l'roll'l!ion Sland<>rd "lid Illal

### ~.**~'~:i:,~~~~~§§~~~:;l:1 II~aled** **~lIlll il~**  

### plJnll, 

### wil or water is co,NaliS**o~er 10flg.~lccvecl**  

### shirl {IOU lflilil P(IIIIS, tlicmi(al**rcsi~lalll** 

### I Iresi\tanl lootwear**plu~** 

### >;(1Ck;, ,:Inrl prolccllve eyewear. ForlI¥crheart**expo~url'.** 

### (-h<il11ical-ll'5l>tal]l**h~ddgear** 

### I lhl' Ii II II h II '1**",</'-'~L** I

# b**rvt-t--~ ~**  ..l I}**V\-"~'4:..-.-/**



# 23

# --------------

..**----~**



# STORAGE AND DISPOSAL

nut (onldlllilltltL' WdIN, loor!, or 

### ked by**snrrag~**or

### di'po<;J1. If 

### conlaliler is brokell or Lonrerrts

### haw' Ipiilelt

### loUu\\' JII precanliDns indk<Jled <lbnve <lltl! 

### (k,jI) lilt immcdiatdy, 

### Iklnrc**de~nrny;** rip, 

### PHI lin frrll length 

### \wust'rs,. long sleeved shirl, prole(tlve 

### glov('$, dOO 

### goggles or IMe**~hjeJd.** 

### wilk up**~pil!** 

### with ,rOSOruCnI rnerli.! suLi, ,1'.**~H1d.** 

### Nlth nr other srritable materia!**~nd** 

### rlispo\('01 waste at ,111 aPlrlO\'f'rj !'i,nll'di"t)<)<;;ll 

### l,lrilltv 

### PESTIODf DISPOSAL**l'e~lind('** 

### \'J.),te$ alt' 

### iJcult'ly lIol7drdoll$ Irnprllpcr**rlisp(l~J** 

### oj**l')((l'~S pe~ti(Urc.**  

### WI"y**Ini~tIJrL'.** 

### Irr rin\Jte**j~** 

### a vioiatlull of fctier,ll 

### Jaw II 

# 'h,,,, ",,,d be**di~llo'>f'd** of by 11'£ ,1nurr1UIY. \0 I,dwl**IIrstru((joll~.** (orn;H\ yO(l[ S'd\(, I'e,\irjilc or Environlllcnral (ontrol**A!!~'I\(y** or tire ItazaruOlrS Waste

# ~~'~~::,"'~'**;~'~"** ilt 

### thr 1tC',lle,t

### fI'." Rewon;d Offiu' [firfllmldw¢ DISPOSAL (rrr equIValent) tire (-mpt1' wnrainel\. Theil oller frrl req'dllrg or rcc(lfluitinning, or**prrnctur~** ,lilt! rli;pow of ilt a <.-lnit'rrl' IJlldliH, or by

## ~~~~;;~:~~Eor-'~::":~~ Ul' stall'

### ,)IIUIO(dJ JllllrQlrti1..'S. hy burtllng If

### COOt,111Ie( i\ burned, 

### \tay out oj

## ~ll1oke

-- REFIllABLE CONTAINERS
use. rellirn Ihe CDaldinN 10 (Itt' POII\I oj pur(lIase 01 

### designated lueJ(iuns.**Ihj~** LOnMroer rnust**unJ~'** be relilled With PREP'" brand Illrcphun fur

<ltld 

### fobalLo. 1)0**~OT** RrUSr rHt (ONtAIN!R FOR .'\NY 011RR**t'LRPO~E** 

### Prinr to relrlling, 

### rn,pw tJrornuglrly for ddmorgl' Sllch <1\**dbra)jon~** 

### Jnd ilJmaged nl ",!)III out t!uedUS till**d/)~ule** tlcvi(('5 Do not 

### rdill or IraMpult 

### d,rrl1aged or Icaking (fJO\airrl'r5 (jrerk 

### lor



### Ii "I

- II 1.lIthL'CVrrlalof'r' rl.l II,rCl\)lnirtdthel II r**~ENI,RAlINFORMATION** 

### conON
A foli,lr ,pray 01 PREP'"**h~fld** I.tlrcphrm for Cott0n ;'IIId 1nl1<lt({t will iI(reicr<l:(' OW'lring ul i1rdllrlt' llrropencrilollrrrr**b()l1~** amf enllJncl:' dcfoli,1lrorr whirh C,)n resull In earlier haIVcst With dn Il!uc.neu re(Ovrr.rbl('**~ir:J1l** PRfP" \r('<1Iorcnt url mt\on Jllor.i inol'ilst;d efJiuenry hOlll il orrcC' OI.1:r hilr\'tSI. TOBACCO 

### (flUE-CURED)" Afoliar sway of 

### PRlI"u hr,lrrti lthcplroll prumolts !\lrJy. rrnlforrn "yellowillg" nl rll,lll11e tou,lew. PRI**P'~ re;jrr(<,~**  (Urlrlg time, / allOWing more dlicr('nt use 01 luring**b~fIl** Sp;rL('. ,'Hit!**irrLlea~'l1** corrtrol over iraIH'\t sdredtlle" SPRAY 

### PREPARATION 

## .lkttr\7,:;!,: '**~. ~'_**  / j0W'.d ,''.dd '1i2 tu 3.14 uf the re-quih:fl JInOurrl 01 w,ller tn rile \prJ'f tJnle StMt ,181101.1Iorl. Adrl the- required ;JI1lollrrl**orpREP'~** brand_ttlrephrm:-aot! the**~~~~,-,~** remaining aOr(Jlrrr[ ofWJt('L Prr[MrC' only**a~** Inndr wrily soilltion dS Cilll be r)\ed orr Ihe rlay III miXing, Do nllt 

### allow Iplir)' solntioo Iu Slilrrd overnight. Do 1101 

### spill the«(lnrt'lltralL'd prurirllt on \pray e((rllplrrent, or ,1rry ,wpIJor'**part~,** ANY SPtltSSHOULD BE RthSm IM\jtt)IAIII Y\','1 tH Pt I,NiY OF WA1(R**U~e**ofa HurS!' t&nk**i~** highly r(,{(1rnrnend<"1i for iWOlrling pO;:;lhle**spill~** uf**(lrr~:fotriltetl** 10Jlrrillatlllll orr Wr,li' eqrnprlltllt ur ani',1iqrIJnf' pdrts TANI\M!XIU1lliSWITH DEfOUANTSAND INSECTICIDES**/'~'-** -,/1£<'**(~,tk"i'4"I·hf"«,,,-<-, (_EP'~** **,,£!~,!I** EthepllPr)**I~** fOlnp,ltiblc with nHI, tOllX'" Dropp', DrO[1p'**Utr<l'~!,** Ginsr;)r2

. ttarv;\de" Methy! P.lfatJrron, Gutlriun\ and Mdlalhi(l1)4 /_rr""''jnay

### lie**app~ed** In \!!qlll'nll' Dr JS ,1 IJrrk rnrx\lrr(' (DO I\OT TANK MIX WIIH 01 <'ICC"NfS II**C01IO~ I~**  10 Ol SPINOll ItARVl-STW). Follow 

### ill!

### i~~,~e lise

### pre(ilutron~ Jrhi rale pL'r arre rrtOOHrrenoa\IOn\ on Iilbeb 01

### PI{Jdun~ applll'd as laok mixlures ur in

### ~qrJeIK(' rvrth

### 1'1fE~

## \ t-/**!~,-** (tmeel!,?a:'In \.Olne (JSl:S**~Ji)\ht** rl'(hl(liull 10 boll up('ning**respoll~ IrJ~** heelr**obY:rw~d** r'ilrerr lank rnixt'S I\'rllrdefnli"nt5were used**~~'-** .•• / 

### V

l\N., Good agitation irr the**~prily** t')nl: i,<,s\('lItial Jlld') tank IlhXhrrc**~hultld** rrot heallowed to 5.1i1nt! wltlr0ut agitalion for rliort': th,)n Sto 10 minlrles ReJd 

## ..;!' <urd ob*rveJIJ ,1pprOprrJle l;rue!**lI~l' rJlrectrDrr~**  (Iod PI**e(Juti()-lI~** lor tire rlelolianb and**1'IlSf'{trcid~-'JI5ed,**

I,**,,&l~¥** " ••..'

..,,""**'~~""'-.''-i'h·,** <fA\. ft."""J-'_ " ," NOTE:**U~I)ER** 

### ct ttrAiN CO"JDITIONS-. T,\NK \ltXitll£S Ot(PRrr''' !:lRA',/O IlHU'1I01{Wt1ll DESICCANT'> CONIAI'-lI\G SODIUM (HlORi\T( (OUt DIRSUll IN 

### THf IORMATION 

### OF ItyPOCttLQROUS ,,00'> WHlfll ONIltAT1fIG\VTllTMlrTOXfcCl ttORlm, rUI>lLS, OU 

### t\o rMIX

## t'RfV"-B~'~~D"r~'HEI'I'iO'l'\\'tTf-t ,'I,t!,IONILtI,1 TI-lIO..,Ulr" IE. ..,unl t..\Nt.: r,tlXTUliES MAY RISUlTtN FOR\IATt{J\ 

### or IUXt( fUMI S. -'" / f 

### EQUtPMfNT**CLEANTNC;--··'~""** "

- -, . <, ,**q~"** ,"',',' '. 

### '7:,;,,,,,,**Bc(01u~** 01 the ,rLidi( 1I.l\rrre oj tiltS pwcillrt, prolnrlg('1! L'!(pn\Ur(' to ,prdy u"PUSrt will darltdg<' ilU}'irllrlaSlil!>, (Ntdir1 pillrrl\ 'loci**m~tals** Rins{' thoroughly Wllh .l drlers<"rrt ,rrul l\ilttr 

### ,)11**e_WO~\!rl** iI<ryJic Irltlsti,**I~(jf InilleriJI~**  (t'.g , ,lirLiafl n'lr\dllrlelds!. and pJIOtet! SllrI,lees within an hour afkr t'Xfm,ur"10 sprJy**df'posit~,** 

### At the end ofeach 

### day, rilile thmoughl" wrth 

### a rleter:,:{'rrt <llrll ""ller all th(, rtrtt,11 pJltsrd Ihl' <rlrrrJlt .)(11llllc ;r\50(lated 'PIM('1lrliprrrellt eXlrO$('(1 to**11r~ ~1>rilY** **d~pn;ils**



# 24**.-.-~--~** ....

### -

..

## ----

# conON

USE EXPECTED 

### PREP'" ONE MINIMUM SPRAY AI'PUCATION CON[)ITIONS 

## RATE GALLON VOLUMES 

### TIMING**PREP~TREA** 

### (Gals/A)·



### Piot>fA "SA.L**,,~** C,m,mrl 

## Ai,'- 

# r i

## 00'"'. 

# . Ilotand dry BU'f (I[ 

### \ 1/3 1.0 b Apply when thl' number**~!** 

### Boll Opener""" Higlier IIIJIIlrI.' ilrlop<'oed 

### boll, SIIII,Clcol 10 prodll(e

- II;; Dry illlJ 7'> 10 BtJ"l 2 15 

# , 

# '" 1 desm'd crop See !lelow lor**h~il** 

# un 2.0 J 

# 0' holl nI,illirily.**Irc~lmerll** (001 hilI ;IDove**G)~I** 

# !**~;~~ormIV** OIlt'11S holls 7 10 14 m cdrliN. 

## I**D~II'** '·

..."'1 

### j 

# ·':r. roLEX· High wil nrOIStilll' 1:3 025 

### H 10 S "ppl,,. 4 

### to 7 

### day, prior 10 

# "'**I'REP'~** 

### tJoll ollel1lOg 

# ,. ITank Mix*

.... applicd!iOIL To be**lI~d** as d Iligh lerlllilykwl SN)tu.'llliJI Irealrllcnl with, 110\ m 

# I**i~ ;;I~(~·~I**  PRI,'" boll opelling

# ,~~ IHalik (OUOII 

# , 

# , , lIigh <.nil rIlOI\\Oll' ,) 111 (Il'}**j~** 10 l 

# !**',;~i~~~** 4 10 7 uavs prior 10 

### Tank**Mi~"  j)f

_ .J; I; hall oj}{'llillg 

# , 'lppli(Jtll)n, loll!' use-Ii ,IS ;j IliKi! lerlilil,! level


# , j** ~qul'nli.ll****tr('~lillcnl** \l'ilh, nOI 01

# - In plate 01**I'RfP'~** hOiI opeiling 

# I,,,'

# ",II"" 

# " " Pre-Condi\ioner 

# '0; HOI, dry, <lliOl'(' UU'f 213**IL~** 11 Apply 4 10 7 days PliOf 

### t" Defoliation (001, doo.,e b5"f I Iii II) & 10 1 dC'ioljilllL trlliancr. top Lrop 

# I defoliation reducing 01

## d('teri~ral~Or~r**~~rl~r';~~::l~()P** Rank (011011

... for besl perfOfllliln(e, 

### by ground 01 .Iir JpplIC<lliOII, chrHlsr cQuipmell1 anli ;pr<lv ..olUllles 1I1at**I\illlll~ure** unllOfrll (GI'er;)!:!!! of lollaw' ami bolls. 

## **

# Pr~treatment Wilh 

### Defoliants Prior to

# .eR[p~raEA~lhephon Boll

# o~ening**Tr~atment_:** IIlht' 1OIIOII

# ISov('rl~ rank or layingdown in I,he

# ~)-**~~~,<,** m,dd[:sand good**~pr.Jy mvt'rilg~**  nl tht" ll1j!ls wllIl(fIRII''::)S dil,h(Uh, il**prl'lr.:~'l!nll'lIl** wllh defoh'II.1IS '1'111 b", !lSd.','1 III Impmn' boll**(I)~'era)\e** Wllh t**rh"',~ ~'pmr'~~.)**  V.-.e dosage**r,lte~** ul PRI 

### P**~** rf'{,Olllm!'rl(Je-rl moll oJ}{'nIIlX, 

### R"au and obY'rI'e all <lllprOpndlc lahclllSf'**rJlr('(llnrl~** Jnd Ijler;)lliiolls for III(' )q '-(f(:fdliil'rll US<:I"I. 

### '/l?,-",) 

# **'" (an I,'>e up 10 hlillabcl f.)le lor Fadl plGlluo 

# e-*
In rilliforniil anrl ArilOna USl' a W!lIffie 01 r.o IL":>S Ihilll:;

## g.)lIo(l~ PN Mrf' lu( aNl,jl ,lpphl..illinm



### Boll Maturity Aboll i:l Olalurl' whell it 

### i

.. 100 hald to Il(:(knled WI'WIl 5qlleeltn belw<'l'n 111I1I11h ,llid III Igel" to.u 11,)rri**t,~** he- dKrd Willi ,1 <;llarp knile, ami whl'n Illl' wed (oal u{>(Omeslighl Ilrown ill (lkll 

### Use Limitations Do nul·(-xceed aln;nlmUIII 01 

### 2(l11;

..**r:HI~hnn ;1(11~r**  illl';rlXlit"111 r><"r ,Ilre [wr year ti1!(lHSb wmhirled 

### or rcp('aled**US('~** 01 any e1hephl)l1 prodillb Boll Opening: Do nollank

## Illi(PfU:P'~**brilll~t[theP!lOn** with <l dcsirr.,lIllli Ihe 1OilOil is to lie sDindle

## Iw\'e~lcd '-**-~,~-'** -**,--~-------** Pr("(,Oiltlilioll lor Oelolialll)ll: On rlu[ \.)nl::**Illi)£l)Rt:p'~** hritiid IlhcphmIwifh desl«(.)II!S**unlM~** p!.)fll dL'Sic(Jllon 

### is rl'quired, 00 oUI t.J<.i' a ddoliallt helore Ihere is \t.JIIIC)I:n.LOlil\llre UflOIJ;CfIS'd hilfi$l(i-p;o(i;-;I:e Ihl'

### dl~ir(.,.j field

### (~el' Gt'llf'fdllnlorlllannll \C(\101l UII hnw 10 1('\1 tOI boillllJlllrity. DO NOT APPLY

## 5'ilfP'~ IIRANI) nHfl'IIO)t'1I

## R>\I~ I::' EXI'I-CHD WITIII:-' G IIOLRS R'!infall wilhill r, 110111'> ul "pplicallnll IIlay rcdUCl' product /Il.'riofllldl)(e .**.-,-.~** "
00 not plJlI1 <H1ollier (rOP wilhlll 30 rl<tr" .)il«r**Ir('~lllIenl.** Slllall gr,rlils pldlllM eMIi('r Ihall \ lllOrllh (II interrruPIXit**,~ilh** Ihe Lunon (fOp In

.....lIlch**I'REP'~** will**h~** ilpplied lila!' 01111' 1J<: used ,1\ ((}Vcr (1011\ and Inal' nn( bl' hdrVl:')te-<1 lor ffinLi or lee" I'RI**r'~** mdy C311W yclloWIIlj\ ilOII growlh 1IIIIibilirm 

### ofIrealed \HlaH grdlns, WHEN TO 

### HARVEST COnON Do nollldl"y(>S1 Wl\on Y)OON IIun 7ddV'S ,llier ,1 Ire,cltm(,nl**\'l~lh I'I{EP'~**  hlilll(1 ! Iheph(lrL**Oh~erv{'** Ihe tr<,,{ted (rnp alld harec\1 Il'h!'11 Dplimum holl**OP('IlIlI~ hil~**  Geen reache·d. Too early**hilf',~~\** mlglil n'<ill(c Ihe full adrarlld?;e nf till' Irealmenl and Ion l'!le a h;lrl'l'Sf !lldY**rt',:~1** III rNluc('d IjUJhlr alld In"(II hr.! l'>'llidll\iU drop hOllllht planl 

# 25 ,/

VDirected SprJY Appll(,1110n

0\'c[·1h(',1 0 11 "pplir<lhOIl --""-----""

J 

## In 'in

I 

## tt, -2m 

# TOBACCO

U5e drup (loale, 

### (hun,!: TG or 0(\pray lips 

### designed, I. SO· 60 S[J<I al 

### 3540**p~i** 

### and ,It 

### tractor ,petti 

### 01 2·3 lurll. 

### lise 

### 2. nozzle, 

### pt'r lOW, 

### on(' Oil 

### eJeli**~ide** 

### oj the HII'! 

### dropped low f'lInugh 10 direct tile 

### ,pray 10 thl' 

### leilves to lie lipened 

### ,md**IIJIVC~I('d,** 

### lhnrough spray mWfilgc 

### i,**f'~'><:'lIli,ll** Willi <l dilli(lcd ,pray.**Jl'~ ~ure**  10 hJlve\1 illl le(lve> 

### willi 20')(; or ((lort'
[reill Oilly \vhCIl Irav!."> I 

### i on IIle**~talk** Me malure. To 

### cmure i i '(**I(',,~('$** art'" 

### o(illul!;, le,l 

### spray seve[iil 

### tobacco pl,1nl\**<!~** 

### db{ril)ed IInder llie S('(llon 

### "Proper rlln(' 

### 01 TreatmellJ" 

### Usc the lower filii:' 

### in a oormally IIIi1ture 

### (rap whell expcnCr1(c**Indi(~lc~** Ih.31 nlminnlfo ripcning indnfeme{li 

### i,rC(luircri Ihe the IlIgller 

## Ir/ [ale i'llit'll 

### tI((' (WP I,**IICd~** and**In~** <1 1t'lidcl\(Y 10 

### tit'. Inure rank or**wh~n** 1l'llIpNJtllrM Me luwer Ulan nnrll!;11 Always test 'ipray 10 dclernllne 

### d**IIH~** lohacco**I~** ") matllfl!enough to**r~~**

### umiJo lreatmentWllh**I'Uff"~** 

### J 

# "'iC""' Applv over Ilie-lofJ 

### REP':.wm.V <1\ a hlle 

### mi,1 1I,In8 Ihle!.' nOlll(,s (onr- 1I0lJle I rWN Ihe u!lIlcr 01 llie pldili. Jlld one 011 edcll ,ide) ,0 Jil le'Wb drc coverC'd thoroughl')'. ,llIlildl 10 Ihe JppliQliOiI IJJltcrn of ,y,t!'mir ,lId:cr colilrol agenl'>, U:,e 1060

### :~~~,~~;;b~,;'nn;d.~~'~.**:~' ~':**  imrnalllf<- !!',we, d, lilis(,lll rMulll1\ 11I1'>JII,bcloryrolflrlllj{.

### I~cigllllo»alid reduced leal qIlJlit)'. Do IlOl dllow 

### r ' I ripen in IIII.' IleitJ illier

## u5inJI;m;'-:f~~l1d**['I'i'I~'~;I:~)lItc** Illis

### roilY (.)llse \I1I!1C rctlurtion in 'iir-Irl ,\lid qUJliw,**""'~~-~.-.** Do nol Ireal helore Jntlfill'II("I1 Iflaior 5torn Iwlnrll rill/id prc\-'('nllmve;1iJrld**r("~ull** in (fOp**In,~.** 

## ou NOT

## <o\PPLl'~'B'RA-~'O-ETtlm)lf**ktV~** IS EXPI [III) WITHIN (; 

### 1101111\ I{dinfall wililln 

### h IHlun 01 applicalioll In.W Icdu(c product periormance.**~-,~-~.-** .. -•..**-~.-** 00 1101

### u~~'-;"br;(ld**EiT\cjlho~~~illl** illl(hlII'C, olher 11I.1n rK:lllliOICllded 

### on Ij)h l)lllcL I)n IInl pidOI allolher crop**\~ithll1** 

### 30 days "ller Ir(,<111 neili. Do [jot ('XCero)l nljlxilnlllO 

### 01 2 Ibs elhrl1tlllll ,1(11\'C Iligrefllt'nt I)N

### JW: Ilcr i'far Ihrongh**ICIH~Jled** OSC\ of illly ,'IIIt'pllOll prodll(I\, 

### APPllO.TION TIMING

## ~uw:$sful r{',lllt"

## IVllh~REP'·~b~~- flh;lIoll tdillor Irealml'nl wilen ic,)I"{'S Me malnre, 1\01 ovrrly rank green wllcll ,pr,1'r'NI fo f'.nily tlelcllliloe Iii

.. proper trcdli'lICnlltllling an 

## 1he-(jU'iI'iber-onb

...r; per ,(Jlk read)' III[

### b;II'.'~L lest spr,1y ,\,,\'Njd rridlll; ill 1ll00e Ihan olle IOldlion in each fielrl and Ob?l;file.th':Hi"fItlfl\e', Mature leav('",**I~ill** lJegllllo yellow In £,1 Ifl 72 IlolIIs T0:51 I("N". Ilul l<1illo ytllow in 72**h(lur~** dIe nol matlll!' ilnd dre riOI read)'

### 10r~~~e~Hn{'m,-.3Waita lewdd\',; 10 perm!!fllrther IIJlurill oliltllflng.

### Ih~n make allOlher I{',I

### ~llril\, or "11 lahlnl\," (ht><k, 

# A amid qualily 

### 10» ,)lId or

## pO\~lhlt' kdl drop,

## IIJr\"e~1 ;IIW ')dluwcU

## Ie,)v('~ prior III d!JPIIC<llion. 

### lise

## 11)\~er ralc, under

## 1ll()~1 {{lilflilinfl}. 

### limit lise

### oi

## ~gh('[ rales 10 mol iilelowf,sr <It lilt' Iline nllreallllclll) slow rillenillg WlldillOll}.

Wilen \'<llrhilve <onlil[lwli IIh' lie',ilen nlJlllb.![ olled"l'\ I)!'( pl;,nt Ihill will (oto)!, '.-"11 Ull**d('\~nnlinl'** Ih{' IlIlrnhPf of**,1cre~** k' I(Cdl ill oroN jll hilihe IMrn**~.-** ,''--- --"

____ 'j Prep,l.re yOIJf tesl 'Ilidl bi',

### mi~i~il 0111'

### ~A~ol I

### OI\PR£~~**hr~~](!yllep!lo.~.!ill** ! qlliifl flf Wdler.

### ~r,1y filrh 1f',1 p!,Ull willi abOul 1 nz ollhi'i InIXIl;fC. (, / ruvcIllIgalileilve5wllh il filic IIIISI!

### ·rRtp'~ )\-,1,1 n]}1 2;ior mWI<l\ur('

### ,pral'",ill£'J\'c~ '------**-~""'-'"** \.



# 26**----~--~.**

WHEN TO HARVEST All mature,

## ~pfilycd**ll'aVl:'~** will hegln to (olor \\1111111 2·1 10 72 hOIlf\ ,lite

## rHfP'~**bral1~e.!l?~i111J1li(alion. Th~**  yellowing

## fJfO(e~S i\ 1'it'i1lher depelldelll; ((Jol \H'Jlher IVIII delay, while hoi, SIIIIII,(wCiltlll'f (41\ 5peco nil I 1l' f()(t

....**~.** Iiollvrsl Ireilla:!lolMlCO when I('ilves Ila\-e Icarhed the deSlre;J WI(H**11IIen~ity_** < '"**"----~** I'lM\'l'5t [In Wl\1l1lel\(1:' 48 hOllf!> ,1Iter!PRI;P·· bfillid flllI'pllonjappliGllion munll(Jr I(MIMcrop Jnd weal her**(oIHJi~- --~-~,-** **~** -- - 10**dtterllHn~ 11~1\·('St**  timing and**~~'old** quality**1(1~~** Of leill drop, rlosely



### CURING PREP'" BRAND ETHEPHON lRfA1ED TOBACCO (liring pror.edllics**~fe** ,1\ mlflh ilil ,ulas i1 KlCIICf' and eacll (life**m(I~1** he IlIdgcrl on tlte IklSi5 olloh,KW (ondllion, 1II1eIVal1ietween Irc,11111('01 Jnll Ilap.:I'Sl, 

### v.
....**iltll(~r** Jnd type 01 (1I(1I1g laoIlly heloll"**pft~tfipli(}n** leffipt'l<1tllrc illidvemilJtion schedilles (all**h~ t5tabll~lIed**  To obl.)ilt m,jXlmum qualily. (arc OIIiSI 

### be laken 1(1 ob\Crve .:inn wnlrol thl' Olflllg prn( es\tlosel\,.**c\pc<iilll~'** duriltR lI(e lale "colorillg' and early "drving"**slage~** ollhe It·d!. 

# ;**rRli;;':~;;;JE~~~** ceall'iJ 10iJa(W will h,I\'c slalted the 1.010ling

## prO(~5S ",hell harveslclJ. redu(illg IIle llioe ft"qlllu:d irl Ihe coloring 

### pilau- 01 wong ft'ille 10 .1(CO**~lIollld b~**  dfied lasteL II tohJu() It,wcs are green or contain sonl€' greell wilen lIJ1Vt'\lal. il way be neusSJry 10 colm fhem 1m a lew houl>, 1I1he le<l\'('\**Jn~** willplelely**'i~1I0\~.** telflperatufe and \cntilalioll must be**Jdllj~lct1** in 

### J.J1!i!. ler IfI dry 

### til(' lobilC(O**il~ 1.)~1**  

### as 110ssible wililOul**~i)lrlilig.** Oncl;' tht" 1('011 

### i,dficti f3r4 dry), yOU il!()lIld loUow IIOf!ll.i\1**pfoc<,duJc~** {Qr**CUfinl-\.~e** PRrJ''''' lC{lled Ie-'t\'(!s (ljfe IJsler, If<'.lled Jnd tlfllrealed h.',lVbshnulrl fiot llf: cilled lug<"tilcr III the Xlmc O,lrl1

### CL-v:'t,t-~<)~ 

### -J0"CV<.->. 1.. 

### 'LI 

## E-b &J AR 

## R 

# ft k!Ti 

## JMPORTANT:READ BEFORE

## USE~M'Jl) 

## D! S CLAL!v\ 

## E.

## R 'J



# •

101 ( anri Guillion <If(' rejw;tered tfad(,lIl)rh

### 01 Il<lF'f AG. (,errrMfiY_ 'Oropp and ('illstdr**~fe** Irghtefe.u**t/'ildCflUd,~** <lnd IJIII;)**I~** {I Iraileln<lft<)1 ,\gr[\'O_ :iHarvdrie**i~** ol registered tr..df'lIJJ(k of\}lIiroyJI (Oll1floll1'j.**~"lalathiun i~**  <l lruuemill

### k(lJ Amefifolll Cy,uldmid (,lflIPollll'

t**il~ ,\,--::..~,-**  AventisCropScience

- 

### <:,,-,v"'"%'"'9""'&1 T ;/'-'0**V"-~** W'" L'0,')h L,- 

### P.O. Box 120H,2 T.W.Alexander Drive Research Triangle Park, Nonh carolina 27709 PllFr

## i~ IIIe IfJdelllJlk ul the

## A\lPn1i~Gf{{!lP; - __

## cj,\,~, 

## '"'\ ;Le) 

# mt LX

## i~ <l ft'glSt('ft:'{1 tf<ll.kffi.ak oll!lf'A'{('nth

## Gmi.!p,~**PR/-P'~** IHaml Elhl'phOiI lor (oltnl1 <HId Tohdc(Q (PENOi1\G) S(lllIllittrd 7/17/01.,

-- {::.J''<-Ct/\'"''

### ~

# t.cJ



# 27

# Aventis Crop5cience

August 12, 2002


## Document Processing Desk (AM.END) OfficeofPesticidePrograms (7504C) 

## U. S. Environmental Prote<:tion Agency Room 266A, Crystal Mall 2 

## }921 Jefferson 

## Davis Highway Arlington, VA 22202-4501


## Attn: Ms. Cynthia Giles-Parker (PM Team 22)

• Sub: PREPbrand Ethephon for Cotton and Tobacco (EPA Reg. No. 264-418) Revised First Aid Statement


## Dear Ms. Giles-Parker:

I 

## am submitting an amended label for PREPbrand Ethephon for Cotton and Tobacco (EPA Reg. No. 264-418) in order to c.ompJy with the directions set forth in the PR Notice 200l-1 (First Aid)
This submission contains the following documents:
l. An application for new registration/amendment (FomI8570-1) 

# II copYI 2. Amended label for PREPbrand Ethephon lorCotton and Tobacco 

# 15 copies) 

# e ffyou should have any questions. please contact me at (919) 549·2302.**Si~elY** 

## yours, " 

# --+i-**?7'>_~"..C** f·y!52.- Prasad Rao Registration Manager E-nlail P[jJ:-'iiltriJ.!J"itil\fJltL\

### (\1111)**A\'''lllj~** CnlpS;;;ielll"

. 2 T\V

### '\1C\,lIHJ~t' Dn..-e I{c;,,;n.:h

## TPnlHfjJ-l'!&R XC 277cr-} Tclcph"Ill' \91'» 549 lunD 

## •••••• • 

## •• • •• • • 

## ••••••



# • • 

# • •



## •• •••

## •• 

# • • • 

## • 

# ..... ••• • ••



## ••• • • • •••••• 

## •• 

## ••• • ••

•• 

## • • 

## •••• • •



# ••••-- --- --- ---- u."**_~**___

- -- -- 

## ----**,--~ -~**  -----**--~---** -- 

# . J3

- 

# '" .'**~**
United St,t

.. 

## Registration OPP Idonlfflet NtmOet 

# oEPA environmental Protactlon Agency

# ~ Amendment 

# ,;J.

# S' ,).5

# '11 W

.. hinaton. DC 20480 

## Other

# ~ ,for
,

# - II
1. Comp,nyl1'toduct Number 

# 12. EPA Product Mot\eo4r 3. PrGpOlod CI

.. IiJic«ion 

### 264418 i Gites--Parker 

# DN- 

# o RHtrict.d

# i4P~EPlbrand'tth!~h;~forCotton and Tobacco PM, 

### 22 5. Heme om Addr

... ofAppUcltnt (lndulh ZIP Cot/llj 

### 6. Expedited Reveiw. In occOfdllfl« with AFRA Section 3(cJj3) 

## Aventis CropScience (bHil. my

### product is similar Of' identical in composition and labeling 

## P.O. Box 12014, 2T.W. Alexander Olive to: 

## Research Triangle Pari<, NC 27709 EPA Reo. 

### No. 

# DChH:k If

# thn,..
n.waddnu

. D, t 

### Name I

- II 

# E Amendm,nt· !.xJJtein below. 

# U Fir>II printed Iobol. in rep.o.,., to 

# := [J A-o-nevl'mlr "ted


# - RnubmI.lionin te.,xJn

.. to AIiI.nov l'It'rdated_ "Me Too· Applic:eon. 

# jj Natillaatl,n· Explain bo!ow. 

# 0 Other· Explain IHIcw,



### Explanation: u
..additNlI101 peg_til) It nKosl-4fy. {For •• ction llItId Section IIJ ReviSed 

### FIrstAid section

### of\tl-IIlabel tocomply with PRNotiCe 2001-1,



### ,- III



# ,

# ....., Chikf..RHlIJtont P.ok.g!/IG

. Unit hckogina Wilier SofubI.Pacboino 2. Tvp.ofContainer 

# Et - V" - Vu

# g~~ N. 

### - No - N. PI

.. tic 

# ..., " d 

### 11 

### -Va'· No. par

### ~ 

## 'y

...

# w" No

.... 

# .....' Unit PlIOkaging wgt. <,ontain.r COfItaintlr 

# """',



# , <. , 

# '.f

..... f

...... 

# U
f. MatIMl in Which label I.**Affb:~** 10 Produ.:t**~-**

# I~~ u "'

....

, -IV 

# 11. ',N, 

# 1".:::"",_ n•• NO'.**{I~** 

### An.eo.:t.) Registration 

### Manager
Certification 8. Oat. Application I ccnilyth61 the ltotomtntl I**h~** mad. on tN.fonn 4ItId eft attIIchmUits thereto et. 1JufI,**_~** and compf,te. 

# ....... I odtnovrledp tim anyknowfir.glty 

### f.,. or mitIl

.. ding .tatemantmay b.**~** byfine OfImprleoM\aM or**.··~edl** both I,jnder IIppIicabf.l.w. : :: 

## ••• 

# II 13. litle 

# : • 

## •
I' 

# 12.,= • • Registration Mlllnanger 

## ••• 

## •• ••••• • 

## • • • • •••• 4. Typ.dN_**5.~o** 

## • • • 

## •••• •• •



## • 

# • Prasad Rao 

## August 12, 2002 

# • • • ••••• ••••• EPA FMm "70-' IRw.

# "04' • ""HI",,, 

# """



# ..... ;1::; I 

# l 29

# _ ......"


### ..**""'.-.~~-----** 

### J 

# • • w. ". 

# ,,. 

# " , A, 

# O""N,.
Unilod Stataa: 

## Registration OPP ld/lMlffot NumbM 

# &EPA Environmental Protection'Agency 

# - Amendment 

# 282591



# - WathiOQlon. DC 20400 

## Othor

I

## for 

# . J.
1. Complmy/Pfoduet Numbtt 2. EPA Product' MaMg/lt 

## 13. Ci

.. dfiCflIlQn 

# 14. CompanylPtoduet INam.) 

# \ PMI

# D~,.. 

# o Rea1rictad.

5. Nam. and Add,.... of AppllCiant 

### 6.Expedited Review. In

## accOld~~~~.FJFRA Sectioo3tc){3) (bHiI. my 

### product is similar or i ' 

### and labeling 

# Ito, ./



## EPA Reg. No.

0, 

## Name j/ 

# \ , • II 

# /

ArnoI'dmMlI'

# ~n b4low. A \ 

# On.• .L inrdporweto datod RHUbmiulen In ,,",pon

..to A;MlcV lener ;;I"IM 

# o**;7.:A~i''''''** No00c6tilm**~** ExpIwn balow. 

# \ 

# o fxpWnboiow. Explanation: v•• Mkfitional p.lslll ,,"OSIUlry. (For •• ellon Seclion II



# / )



## . • 

# 1,. " Will

.. 

# / \
Ch!Jd.RwUenl: Patlkaglr.g 

# ;/ Iw,,,, 2.T",", of**~ntai,,*i** 

# Bv,,' 

# 18:' f= 

# v" \**~~W** pjptic 

### N. N. 

# .,- 

# •**.;~** N ••."" If-Ye." 

# '1/••.., .. Pop" 

## must

## ~~il , ' eent_fl.r Pad:.aga WIJI 

## .". 

# , \

# ~~

# ...
,0 L.oboI 

# o ConteiMf

# ~/ , ••""' I 

# \

6. MbnMt In Which Labell. Afftxe<f,n: Pt()(!OOt ,. 

## ,\

# ~ U Oil", ."\ 

## ··IV 

# '\**1.Co_tP~"** 

# ,H. 

# '."'- iN

..."**Titl~** 

# "" No. (tl'lClUda At

..Codel



### Certification 8. Oat. Applin.tion I aortlfy that tM etot9fllOnili hoWl moo. onthisform or.d ell attachments tMrfito etetrue, ooeut.tte end complete. RflC.elved Iaeknowl.do- th.t

## -nv knowingly f.h,. Ofmislood#lg .t.lemont maybe, punilhilblebyfino 01' impriumment {W' 

## I (Stamped) both under**~!lc:WI.I.w.** 

# 12. SigMWte 3. Title

4.TvPed Namo 5. Dille

EPA.om> 657'" tRoy,

...., 

# ... Whlu • El'A ""Copy Appllunl Copy

# •

PAPERWORK REDUCTION ACT NOTICE 

### ond INSmUCTIONS

INSTBUCDQNS; 

### Thi. hlfm ill to hoUled fot fill appjlclltiCru: for mow tl/gillff.tion,**~md** UII" 

### '"/Ioh.trauon, amendment, toBUbml.don. to 3PPfjeation!l 1(1( MtilloaU:-, 

### final prinlod 1ab«lfIQ. twogi,tratJon, ote:. In o«ilu to PIOCOIII '"."plle,ti"n for II new ttgisuation 'ubmined onthi' form, tM f!lftowing metflfial rmHIt Mleotnpanythe**~cn:** 

### f. Cartlflo"tll," with nefPoctto Cit.tion 1)1 OIftD (EPA Form 857()'291. IIf flO! n:emptltd by 40 eM 151.81 tb114lJ: 2.**~ntW**St.temont ofFomwtl IEPA Form 867()."iJ 3. FonnuIatw'. Exemption Stetflmftnt (V'A Fo"." 8:510-211; 4. RVfI 1IOpi

..of draft l#beling; 5. ThfM copk. of anydltlo .ubmluod; 6. Authorization tatt" who,.**~c.ablo;** 

### 7. Matrlou whel'li eppIIcebfo. I'''''''''','''mo''''',,"'',. Labllflno .MoIdfir.t b. IIUbfri;tttd in tl'lo form ofdraft Iabo!

.. with aU applications fot new tegi,lr.tkwI. Suchdr.ft illboh, mIIV bt jin the- fCfm crl typed fetal !arton 8.5 x 11 tflll.h peper lot IWbmiu.ion Ot a mccl::up of

## tn.**p~** fAba!. Ifprepac-.:i' fM**~,** 

### It .twukI bo in. way '" 10 feeHitet. stolage in on ItS )( t 1 inch file. Mockup lebels eiorJficantly turuII1ar than 8.5 x 11**inchu,~** be/l'lQUntod r.ln 8.5
:x**l1i,r.c~_ ~~!..fot**  aubmiulon, OIlUl wbmlthtd In $UPport of thi' I/iPpflutlon mutt be tubroitttd in II(lcordM\Cle with PR Nolle. 8&-5. 

# AI**1~~~I!'IS!r!~~U!~~1J.!~.PlaaJI-III"d** the imtNOtion:o

# ij~t&d bafew bol(>r(1 completing tNc 6pplie4tien. Fiun det.nnine 

### tho

# "C~**:~,:~'~';"~~"'::II** i**~c.~.O(l, ~".t.~**  in**Bl~ck_~:.~~.W~~h** you .fe IIUbmittinu thill !lpptil:tltion, ,fot**appllllation~ S-\.I~ttlJd**  In**COO(wH)Il~n wi~**  N"w new.Uetion

_ II,**I~~I** fa c(jmph!titd by the I!ppikent. FOf applkatione wbtrutted m COMGIlli/Jf\ with amend&d Hllt6Q'III-tr.tioh .ction-c, ra#ubmlt-.lOM. tategistr.t$oM, 

### .te" Section, I. II. end IV must b. e-cmplotl!<l bytM llflP!lcant. Ch.eIt. th. tlppfOptiate eetlnn for which you ere submitting this form.

## 1~if!;:r!Qnlu

'··This lIIeetlan mullt DI6 compi'lI!&O,

.. IIPPlh:.ulbl., f()f all 

### reQielte«on .etlorur. 1. Ct!mpfllylProduct Nul'tlbv

- tnsert your C!m1pllflY Humbt!T, if Qra rnu: bllum 1I,.';on\tJJ by EPA. Thk numbef mayhe

.... befll ".fiQtl«i to yw I!lIi /I bMie r.gi.u&nt•• dilltribuwt, '}f all.., .,tab!illt-.I'!Unt. if**'t~t**ptoduct i. t3-giJitellld, tnJilllrt tho Pr/'4uct Numb.t. 2. EPA**Pt~** Mana

....• II 

### Known. t\I! in.the: mIDltlffld

### PM hUrrU.l!1t of tM EPA Ploduct MflMQ$r. 3. Ptop_d a
.. -.mc.t1on· SpeCify tM ptOfX>H;d etfWriflutl.;;n of

### 'tN.prmWM. 4. ProduatN.I'I'MI'**fntoth~.-t.ptodl.ltt** n_{II thiJil**~,t(cldc'$1t** will $(>pller Of! tho label. Tho nllmO mullt b.**~f!c** te 1'.hI$ptadvct rmly. Dupfication of 0IImfl i$ no-tj1!uminod liffHH)Q p;odvcu- 01 tttl'l $JmW Ctm'tfi8ny. Do nIlt Indtldfl lIny 

### In4rld 04lM- W ¢Ott'IfimV!intl**d~tloM.** 5. NOrM /MO Ad....,.**clApplkaiot~** 

### Tho twI'Io of dHl fifm or ptf&G1'! 

## .w**1'Idd~$** ,hown in yetit**~¢4t!M** it tM I»f1IOO or firm lG.-)YMm tho**1~{Jl**..tr.t1on 

### will b<llsw.d. Ifyeu ..-.$4ung 

### 1ft bohalf of llOOthor !NItty, 'fOOpl\Wt $ubmit .uthoritatitm from thllt pMty to lIUlt flU 

### thorn In**~n1ion** mau.r•. An appfic.nt not l.mdilllJ in tho Unltod Statn mutthiNt VI .ruth<.irtzed itQllnt wthungln tim Urntad Slm

..tt act fo1 them 

### In Ill! 

### IIIW,Uation mDttolll. Tho fl«im. rrod vomplllt.**mGi~ng** oddlU5 (if 

### $uth!!f!**a~nI** tm!_1It 

### aeeompony fhli 

### Dpptie.tion. S.

### ~dll.d 

## '\6ww

. FjFRA 'OI!etloo;} fe} 3 IBI

### plOvkh~$ fot IIxvtlditee reVilllw ot

### ~fltil}W$ fOl' ftQj5UlltlOn, or

### ~nu to

### .Jdftl~"'~~::~:'4i that lit.

### t®mlI., ()f id.noe.l to otMr**PlJlltickll~** ptt<ductl:th6t anI Ol.iffOnUy I.t.r&d withtta- EPA. In

## oro.t tOf y«lt aPPIIcatklfJ_IO :.**e~pOOit6d** reviow, ytJU mutl1 I)fOvWO u" with tM EPA ReQillfhlWn Huff\bll( 6ild pMUtt n&n'I!!I of tM proouct yeu b.IIl""". 1= similar to at YOUt ptoduct. Tholl ptoduetmuJ.t b. timilllr or idelltkal in 

### twtn fuqnuhltWl'l .nd lilb6lbd U$OUI.

1. Subi-et ot, .l.Ibmis,don • eM!)k the nppticahle binck. ami prov>dlij tM AOl'ney t"Uerd.11I H J!lf'PfepriMo. PU.I\Ikf" e britf .xlilfI:Mtmll.9f

## tn.**PUfJ1$'li.{~1** fot tM \Wbmi,tit>fl. su¢h Ita -the

### ildd,tlo" of it site, ye$t ct filliP {!lplleifyt; -nmend tta (01)fid!lntia1**St6t~t** of formula bY

..,"; -,eteoistrntion ftUbmlWOl\-; -(JeMroilatm**r.~** 01 u,.**d;,&<::tlGIW.~** Anlleh III iMP.tete P&Oe iI itddlfiomi1spae. i.t tloW4crl.

## ~~~~"~nl~:::::~ and COrita/ruft Infotmilltien!

- TNt Sectil;1n mus-t be eorrq}/eted fet a!luppfieatioru: Mlbmitted in oomaction wHh new amtndmal\t$. 1, TVPft of PmegIDg**~** Chocl<; 

## tn. apPlepritltj) Meck if VGur ploouet w:llile pnck_Oee in 

### tt.

.. mdi.mtOO plldegil'lQ t'm". Indfeete tho .-11" of 1Mindividual fHlckM1 aM numb.r I'M tHai! CiH'ItMnlH. 2,**T~** of

## n-.t.a**~tlllt.r·** todleat. typt <'II centllil!M in whic:h filiXlm:-t will bo rn.,btlld. 3, L<'IC8uon of N.t ¢ofttOJ1t1' • Inditat. tl'<$loa!l:tion oftho rat 1,l0n«tnU'lnlorrnalion fat '{t:Iur PI(>duc:t. 4. Sluts) Qf**Jk~ Cont~·**  SJMiC'i(y tn. IUtt eOOl/mt, 01 tdt fateil oonwl>OfS for yoor saoduet. 5, LOCflIkm of

# u.. tXr.ctf_· IMiGlite tho loeaMl'lot thl! U$O dllltCti<'lM fot YOiII Ploduct. S. MlllfflH' in whict! Jebtil!. affb:ed to ptodue1

. IndieiJt.d the matfwd productlab&! if 1Irn.;::hDd to rotall ecntoiflltt. 

### ltV ' Pnln Tro' S.dion roupt be enmpj"ted fot oII.,:;phcllt'oml for RegiJlr.ation ."tionll. I_e., new prodUclO rogiGtr.ti(ln,**~na.t(lo."** tlllegi'-lrotion, .tc. 1·5. Soll-flxplflMtory. G. EPA UN 0nI,/,

# •

• PRASAD RAO UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, 

## D.C. 20460
08/21/2002



## AVENTIS CROPSCIENCE USA LP P.O. BOX 12014 

## 2 T.W. ALEXANDER DRIVE RESEARCH TRIANGLE PARK NC 27709 OFFiCEOF PREVENTION, pESllCIDES A.NO TOXIC SUBSTANCES



## PRODUCT NAME, PREP BRAND ETHEPHON FOR COTTON AND TOBACCO COMPANY NAME, AVENTIS CROPSCIENCE USA LP OPP IDEN1'IFICATION NUMBER, 282591 

### EPA REGISTRATION NUt·mER: 264-418 

## EPA RECEIPT DATE, 08/15/2002 

## SUBJECT: RECEIPT OF**~YJENDMENT** 

## DEAR**REGISTRfu~T,** 

## The Office of Pesticide Programs has received your application for an amendment and it 

## has passed an administrative screen for completeness.**Du~-ing** 

## the initial screen we determined that the application 

## qualifies for fast track review. The package will now be forwarded to the Product rlJanager 

## for review to determine its acceptability. 

## If you 

## have any questions, please contact C. Giles-Parker, Product Manager 22, at (703)-305-7740

.



## Sincerely,

# <~;t/Aat· Front End Processing StafE Information Services Branch Program Management and Support Division

lnlcmCIM<lr1iss(VRlj. http:ir,\i·",w.cpa,gcv**R~d«lm.;;;)'d~bI0'** P,I"I"d MIt!**Veg~u.bl(l** 011**&~ed** l"lIson Recyd.,d PaperIMI"I,.""" 50%**P()s!cOn~u'M'** co"lc"l) 

# 3 2**-------------~**



# ..**,-.~;.,**

# ....**~**

1"HO;-':'I" rCND"I'Il()<'I':SSING APPl,ICATION INF'OHMAT10;'\ C!IECf( I,lST



# -- -_.**~---- --.~** **~** 

# --**----------~--~----------** --.

# __ .--------


### PM 

## ,,;2?**~--~**

# EPACOMPANTNUMBEI1.,,~Y"I- 

# Si//(

,

, 

### '1MB-TOO" CITED PRODUcrSTATUS 

# A<;rrVE,

__ CANCELLED'

__ NOTINREFS,

__ _ 

# •

•

33

## WITH DATA


## !NIT.
FEU

__ 

# SIG(DATA)
__ PM 

# •

• APPLICATION FOR AMENDMENT



# DATE NO DATA 

# !NIT.
FEU-7'-:'

# ;(J**~**



## • J PM**.~.;2,** 

# DATE

OPP #

# ,-?,f2;9

# s-9/

34

# •

• PESTICIDE REGISTRATION ACTION TRACKING SYSTEM (PRATS) CODING FORM

BAR

## CODE~g16~ ID NUMBER: 

# :2.(;'-/-'-/**l~** ACTION CODE, 

# 300
PM, 22 

### RSVIEWER'._-EG\."2-UiVl DUE DATE, 

# \I I 

# 13 1(l2

DATE ON

## APPLIC.~TION, 

# "l I 

# Ib I 02-

EPA RECEIVED DATE, 

# 'K / 

# 15/ 02-

PM RECEIVED DATE, 

# 'i / r;; / 0 :2-
APPLICANT,_AlLe.vJ:

# I;S 

# Cd-v-r ,sc:-;Vb C-L

# JPI'el. s= 0 

# J. 8,,, 0


### CHEM CODE 

### (11, 

# Q

# q

# '1'30 I CHEM :

# -"E-c=-l±1

....**,,'+,~~>.Jh!:..Uo<JhLL..------** CHEM CODE (2) ,____ _ 

### CHEM,

______________ __



### DATA REVIEWS:
HED: RCAB

__ _ TB,

__ _ RCB,

__ _ DRES

__ _ OREB

__ _ 

### 10

__ _ EEB

__ _ EFGI'/B,

__ _ ERCB,

__ _ BEAD, ACB.

__ _ BAB,

__ _ 

### EAB

__ __ 

### RSB: PCRS

__ _ PRS,

__ _ PCS

__ _ PM Team: Carl

__ _ 

## Paul Vern,

__ _ 

## Bill



## --- FINAL ACTION, RESPONSE CODE, RESPONSE 

### DATE:

## _1_/-
75-DAY 

### RESPONSE: YES NO MOS: (1 ) 

### CITE ALL
CRP: 

### YES NO 

## 14 ) NOT APPLICABLE


### RESTRICTED USE, YES NO (8 ) 

### SELECTIVE


### EXCLUSIVE OSE: YES NO


### MANUFACTURiNG USE: 

## YES NO
CONDITIONAL REGISTRATION/UNCONDITIONAL REGISTRATION


### NOTES:



# 35

# &EPA United StMo' Envirlmmflntol Proteetkm Agonoy Office of P"ticide Program. tH7505C) 40t M Stroet SW ( ("' Wa.hinUton, DC 20460 ,- 

## Notice of Supplemental Distribution of • Registered Pesticide Product**~::.:~:~a~~,.~e,gistrant** has obtained final registration for the basic product. the registrant may then supplementally

. hislher product. One form must be submitted for each distributor product and must 

### be signed bythe Involved. The basic registration number and the distributor company number must be shown.

### ;~~~;~~~;'a~ has 

### a potential distributor who does not have 

### a company number assigned, shelhe should have 

### the apply, on letterhead stationary, to the Registration Division to have a number assigned prior to submitting to the agency. Notice of Supplemental Distribution must be submitted by the basic registrant. The complated form must have concurrence and signature of both the registrant and the distributor.

Note: Do not submit distributor product labels Product fbQic**prodlJCrflllm(lllCc.,)t~** by EPA}**N~. Royst~r-Clark,**  

## Inc. 999 

## Waterside Drive Suite 800 Norfolk, VA 23510 

## Cottou (Iud POPIn!



### R

..

d AllCondition. &forti 

### Signing



### 1. The distributor product must have the same composition 

## as the basic product. 

### 2. The distributor product must be manufactured and packaged by the same person who manufactures and packages the registered basic product. The labeling tor the distributor product must bear the same claims as the basic product, provided. however, that specific claims may be deleted if by doing so, no other changes to the label are necessary. The product must remain 

### in the manufacturer's unbroken container. 5. 

### The label must bear the EPA 

### registration number ofthe basic product, followed by 

### a hypen and the distributor's company number. 

### 6. Distributor product labets must bear the name and address of

### the distributor Qualified by such terms 

### as ·packed tor.•.•·distributed by

...·; or sold by

...• to show that the name 

### is notthat of the manufacturer. 

### All conditions of the basic registration apply equally to distributor products. 

### It is the responsibility ofthe baaic registrant to 

### see that all distributor labelino is 

### kePt in compliance 

### with requirements placed on the basic product.
Distributor 

## ••• 

## • •• irorond to m6lktlt 011'product und"th. DistributorProducrNama $ptlCifi...-Jllbow, IJIlb;.ct re th_ com1itiortSJlptlCif'ftHI

### 0,;

# ·th-'NoD

.



### Regiatrent 

# .....

# . • 

## •• 

# . 

# .
••



# ...**~**

# .. distriblltor f'lNtMd ItbOV1ll may distribllta.rnJ$11/1 tha DistriblltorProducr

### ~&d**Itbo~.** $ub;.crto til.

### cOf'ldltloM~M • 

# •••• • 

## •

••••

### Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response, including time for reviewing the jnstructions, searching existing data sources, gathering and maintaining the data needed. and completing and reviewing the Information. Send comments regarding this 

## burden, to chief, Information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070·0044), Office of Management and Budget, Washington, DC 20503, Marked "Attention Desk Officer for EPA."

• 

## •• 

# •• •



# ."

•••••• • 

## •• • • 

## • ••• •• • •••••• 

## • 

## •• 

# , 

# .

•• ••••

## • • •



## ••••• • •••• 

# . . •••• 

## •••• ••••• 

# 37 

# •

•PI(lUO Read 

# &EPA Ullited Stalot EnvironmllOllIl Protmion Agency Office of PHlicidlll Prog11lm. tH7S05C) 40t M Str", SW Wuhington. DC 20460 

## Notice of Supplemental Distribution of a Registered Pesticide Product

a registrant has obtained final registration for the basic product, the registrant may then supplememally 

# I**~:~:~:g~:~;hjSlher** product. One form must be submitted for each distributor product and must be signed by

### the 

# I**~** 

### involved. The basic registration number and the distributor company number must be shown.



### a registrant has a potential distributor who does not have a company number assigned. 

### sheJhe should have the distributor apply, on letterhead stationary, to the Registration Division to 

### have 

### a number assigned prior to submitting this form to the agency. Notice of Supplemental Distribution must be submitted by the basic rogistrant. The completed form must have concurrence and signatute of both the registrant and the distributor.
Producl



### Note: 

### 00 not submit distributor productlabllls Rooi.llred Product Ibnie'prcductn_ tlCcoprtHibyEPA) 

## brand Ethephon for Cotton and Tobacco ! Oislributor Produci Nllmtl 

## IPrep brand Ethephon for Cotton and Tobacco

8I'ld AddlHS of Oislributor ITypo:incJudo ZIP cod.1 

## CRoP P{(.CDll..-c

....

\ 10 N 

## !;f!;/tv lc-eS I

### INC~ 

## z52>"- "'-. 7 I

# "*- 5"

# 'e""T

### p~ 

# o. Box 707500



# ILL I", "- 

# 0 K 7'1170

- 7500 Condition. 

### &fortJSlgnlng

The distributor product must have 1he same composition 

## as the basic product. The disttibutor product must be manufact1Jred and packaged by the same person who manufactures and packages the registered basic product. The labeling for the distributor product mUSt bear 

### the same claims 

### as the basic product, provided, however. that speCific claims may be deleted if by doing so, no other changes to 

### the label are necessary. The product must remain in the manufacturer's unbroken container. The label must bear the 

### EPA registration number of 

### th. bnic piCd

...::;t. 

### f;::.:kj\".'ec 

### by a hypan

..rid the dietributar'S: company number. 

### 6. Distributor product labels must bear 

### the name and addtess of 

### the distributor qualified by such terms 

### as ·packed for

......distributed by

..."; or sold by.•.• to show 1hat the 

### name is notthat of the 

### manUfacturer. 

### 7. All conditions ofthe basic registration apply equally to distributor products. 

### It is 

### the responsibility of

### the basic registrant to see that all distributor labeling is kept in compliance 

### with requirements placed on the basic product.
Dlitributor 

## • irl(flnd to 

### mllfi:or ourproduct undu Ihll Oistrjbu(crPrCduCI Name #p.clfifld 4JbOIlli'. $ubftlct to tht1 conditions$p«ifilld**~** 'lJt.it Notico.



### Registrant 

## •••••• ••••

: : ;111 • 

## •

••••



# • • 

## •• 

## • tigrett thtH 

### Iho distributor

### n.mod .bov. mllydhitribur.1tfId $IlJl the OistTibutorProducrSfH!Cffntd .twvv, 

### QU&;.1:tto rhft c:pndilfpns $p«:ifi.don this NoriC/l. • .:•••

Signllturr 

### lnge H. Davis, 

## stration Coordinator

Form 8570--5 (R

..... 2-921 

### Pt

....ioo. tldititm. lIle o04OIot•• 0"" 

# •••• • 

## •••• 3-

# • •

Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response, including time for reviewing the instructions, searching existing data sources, gathering and maintaining the 

### data needed, and completing and reviewing the information. Send comments regarding this 

## burden, to chief, Information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070-00441, Office of Management and Budget, Washington, DC 20503, Marked'Attention Desk Officer for EPA."

• 

## •••

• 

## •••• • •••• •

## ••••• 

## • • • 

## • • • 

## • 

# , •••• 

## • • 

## • • • 

## • •• 

## • • • 

## •

• 

## •• •

## ••• 

## • 

## • • • • 

## •• • 

## •••• 

## • • 

## •

•••• 

## •••• 

# • •••• 

# 39 

# ,

I

## -**--~-~~~~---~.---~ ~~-** **---~---** 

## ------------

'I

# aEPA "

SIIUOS EovlfMlmMI41**Ploleel~** AIlOllllY Ollie,01 ,."Hoid, PUlllltn)llH750SCI 40t M511"' SW Wt1Ihinglon, DC 

### 20460 

## Notlca of Supplemental DistributIon of a Registorod Posticide Product Instructfons 1':1

.



### AIUH 3 tllgi$tntnl has obtalnod Unal roglstralion for tho b••

### k: prodUCI, tho rngiGlr;Jm Tlmy 

### than SflPil!tllTlUntillly 

### dblllbule hislher product, Ono 101m must be submIt/ad for each disttibutor product and must be s.lunad by lite dlst/ilmto( involved. Tho basic fogistlillion IlUlnbflf alld the dislfibulor cornpilOy 1I111'11ber must 00 shown, 

### II it 

### leuistranl hal. potelltial distributor who does noth,lVI a company numbsr 

### assigned. sho{)\Il should have the dis/ributor apply, on lottorhOiJd SliltlonPfV, to the Heo)sualion DIvIsIon to /lava a lIumbor iJssiOnod 

### priol 10 

### $ubmiuinu Ihisform to the '(lency. TIl;!;. Notice of 

### Supplemental Dlm)butJon must be s.ubmitted by 

### the basic fog/want. Tho complotod form must havo tho concurrence *00 

### .ignltur. of both the registrant and the dlstribulor.
EPA 

### f!.cDjalllllon NumbCM' 01 P,ccll.llli Db:lrlblWII CMI'I/'IIII'IY NumhllW' 

### ,I:

### 264-418~...:'i

## __**~_~**

## __**~**

## ________**~**

## __ ": 55467 ._.•...

_..___________ . ____



### TENKOZ. 

### lie, 

## P.O, 

# oox 1036 Note: Do 

### not .ubmlt di.trlbutor produtit l.b,l,

315 toml 

### CAMELLIII BOOLhVARD**pO~r** 

## VALLEY, GEORGIA 31030

1. 

### The distributorproduct muat have the 

## ume compo,ltlon 

## as the basIc product. 2. The distrIbutor product must be manufactured and packaged by tne ume person who manufactures Ind packages the 

### reg!.ttred bI.1e product. ), Joe 

### lilbetinO for the 

### distributor product mUllt boar tho 

### $limo clllimlJ; '$ 

### tho basIc product, provided, however. that

## ~ecmc dalm. mlLY be 

### deleted If by doing $0, 

### no

## othe~ changes 

### to the label Ate 

### necesury.

## ~e product mUlt remain in the meoufactuw', unbrokef1 contamer. ' 5. The 

### la1>&1 must

### bear the EPA 

### registration number ofthe basIc product. follow&d by • 

### hypan and tho dIstributor', company 

## number. 6. Distributor prodUCt I,bell must bear the namo and .ddr."of the dlstrlbutOf Qualified by such terms 85 

### "packlld for",:distributed 

### by

....; or sold 

### by

.... to show that 

## the name I. not that ofthe manufacturer, 7, All 

### conditions of tht! basic 

### (egistrati01'llipply oqullfly to disttilJUtOf products. It Is the responsibility of tho basic 

### registrant to set 

### that aU 

### distributor**labll~ng** 

### is Jc&pt in 

### compliance wit.h roqufrflmonts placod on 

### the basic produci. Oi$ltlbutot Nh inrtmd

### rll tftMk.r

_**~cr** lind", Ih" DllrtiblllDti+Ddu",r N_$pf>{!ifiM/tb(>Vff, Aub/l>cr t(l ,h. o:tmrlilmfl.'t "pt>Cifiltd011 tltIs Noricll.. • •• 

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" 

### " 

# &EPA Notice of United SIBI1)1I Environmentsl Protection Ag6tlcy Offle

... of**P(l~llcide** Programs (H7505C) 401 M Strool SW Washinijlon, DC 20450 

## Distribution of a Pesticide Product



## Instructions 10-31·95

After a registrant has obtained final registration for the basic product. the registrant may then supplementally distribute his/her product, Ooe form must be submitted for each distributor product and must be signed by the distributor involved. The basic registration number and the distributor company number must be shown. If a registrant has a potential distributor who docs not have a company number assigned, she/he should have the distributor apply. on letterhead stationary, to the Registration Division to have a number assigned prior to submitting this form to the agency. This Notice of Supplemental Distribution must be submitted by the basic registrant. The completed form must have the concurrence and signature of both the registrant and the distributor.



## 264-418-,
Note: 00 ncrt submit dlS1ributor product labels oj R"OistereO Producf /b8$k: producrnlHrnJ IK:CCPttfdby EPA) Dit:fribulor P,oduef Name



## Alabama Farmers Coopel'ative, Inc. p, 

## 0, Box 2227 

## Decatur, Al 35609-2227

ReadAU

### Conditions **Before** 

### Signing 

## Prep brand

The distributor product must have the same composition as the basic product. 

## for 

# Cotton and Tobacco

The distributor product must be manufactured and packaged bythe same person who manufactures and packages the registered basic product. The labeling for the distributor product must bear the same claims as the basic product, provided, however. 1hat specific claims may be deleted if by doing so. no other changes-to the label are necessary. product must remain in the manufacturer's unbroken container. The label must bear the EPA registration number of the basic product. followed by a hypen and the distributor'S company number. Distributor product labels must bear the name and address of the distributor qualified by such terms as ·pack&d for

......distributed by

...·; or sold by

..... to show that the name is notthat of the manufacturer. 7. All conditions of the basic registration apply equally to distributor products. It is the responsibility of the basic 

## •••• registrant to see that all distributor labeling is kept in compliance with requirements plaCed on**the.~uic** 

### product.
Distributor 

## •

Registrant 

## • •

•• ••• 

## •• 

## • • •• •



## •••• • 

## ••



## •• • that tlw d;slriburor fJlffllttri above may distributelUIdsell the DistrilmtorPr-odlJctspec;(ifXiltb-oYe, 5lJbjcct ro the conditioM tiptXlirmi 011 

# Ithk IV,

### rico,

8570·5 f

# • •

Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response. including time for reviewing the instructions, searching existing data sources, gathering and maintaining the 

### data needed, and completing and reviewing the information. Send comments regarding this 

## burden, to chief, Information Policy Branch, PM 223, U,S. Environmental Protection Agnecy, 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070·0044), Office of Management and Budget, Washington, DC 20503, Marked"Attention Desk Officer for EPA."



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Notice of Un'lod 518tcII" Elwironmcnlal ProtectionAaencv Office 01 Peslicidtl ProglUms IH7505C) 401 M $"(1011 SW Washinglon, DC 20460 

## Distribution of a Pesticide Product



## Instructions

a registrant has obtained final tegistration for the basic product, the registrant may then supplementally 

# I**~:!:;:~~:~:his/her** product, One fotm must be submitted for each distributor product and must be signed by the 

# J

I 

### involved. The basic registration number and the distributor company number must be shown.

a registrant has a potential distribu10r who does not have a company number assigned, she/he should have the 

# Id;,.,'!butor apply. on letterhead stationary, to the Registration Division to have a number assigned prior to submit1ing I 

### form to the agency. Notice of Supplemental Distribution must be submitted by the basic registrant, The completed form must have concurrence and signature of both the registrant and the distributor, Rcg;

..tnllion Number of Product Companv 

## i 0,1 

## 3S Note: 

### DD 

### not submit distributor product labels Registeretd Product !wk;prot/Utlrmmw IICCtlptlXlbyEPA} 

### brand Ethephon for Cotton 

### and Tobacco

Name end Addr,," of

. 

### ZIPcodtlJ



### SOllthern 

### States Coopen'ltivc, Inc. P. O. Box 

### 26234 RiChmond, VA 23260 Oi$tribulor Product Name 

### Southern tes PREP brand Ethephon for

1. The distributor product must have the same composition 

### as the 

### basic product. The distributor product must 

### be manufactured and packaged by the same person who manufactures and packages the registered basic product. The labeling 

### for the distributor product must bear the same claims 

### as the basic product, provided. however, that specific claims may be deleted if by doing so, no other chang"es to the label are necessary. The product must remain in the manufactuter's unbroken container. The labe! must bear the 

### EPA registration number ofthe basic product, followed by a hypen and the distributor's company number. Distributor product labels must bear the name and address of the distributor qualified by such terms as -pou::ked for•..,-distributed by

...-; or sold 

### by

...• to show that the name is not 

### that of the<manufacturer. All conditions of the basic regIstration apply equally to distrib,utor products. It

### is the responsibility of the basic registrant to see 

### that all 

### distributor labeling is kept in compliance with requirements placed on the basic product.
Distributor 

# •

# .. inwmi to marketourproductumiM the Distributorp,O<!uct Nttmit**~p#C;mxI**abOV6. $Ubjt>ct to tlw condition$spoclfHXIon

# th. Noh

. •••

_



### Registrant 

## • 

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## • •••• 

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# .. •• • • • •

I QlJIrnI thst tho

### d~""'"to'm_'"

### ~~o" maydistTibuw Md!Wll llu. Oigtributor Product8p11dfi«JuboW". subject 

### ro tho

### corntl,J~;~!it1d on !Jrm Noliell. • :.: 

## •• 

## •

EPA Form 8570·5 

### iRav. 2·921 PUW'OU$ edilion,. oro ol»olcto.,- -- - 

## -- --"**~---** -- 

## --

- - - -**~** 

## - 

# • 

# •
Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered PesticIde Product is estimated to average 15 minutes per response, including time for reviewing the instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the Information. Send comments regarding this burden, to chief, Information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 

## 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (DMB No. 2070·0044), Office of Management and Budget, Washington, DC 20503, Marked"Attention Desk Officer for EPA."


# • •



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________________**~_~_** 

# 44Uniled SIal!)!! EnviroomootQI Proloction Agoncy OUial' 01 Pesticids PrO\lIlWT19 (H7505C) 401 M Strtlet SW Wumingloo, DC 20460 

## Notice of Supplemental Distribution of a Registered Pesticide Product

a registrant has obtained final registration for the basic product, the registrant may 

### then supplementally**~:::;::~~~,lhiSll\er** 

### product. One form must be submitted for each distributor product and must 

### be signed by the involved, The basic registration number and tho 

### distributor company number must 

### be shown.**Ifl;~{;;~;~~;'.npt!** 

### has a potential distributor who does not have a company number assigned, shethe should have the**~** 

### apply, on lettethead stationary, to the Registration Division to have 

### a number assigned prior to submitting to the agency. This Notice of Supplemental Distribution must be submitted by the basic registrant. The completed form must have the concurrence and signature of both the registrant and the distributor.



### 264-418 

## ! n09078 

### Note: Do notsubmit distributor prodUC1labels 

## 8thephon for Cotton and Tobacco

of Oiutribt.ttor 

### tTYPI': includfl

### ZIPcodtlJ**Tenn~s$ec** Fal:TIers Cooperati-..'e P. O. Box 3003 

### 200 Wa.ldron ROCld J.aVer':ine, Tennessee 370136-1983 

# "-- en-oPR 

# PREP brand £th

The distributor product must have the same composition as the basic product. 

## for Cotton

The distributor product must be manufactured and packaged by the same person who manufactUres and packages the registered basic product. The labelina for the distributor product must bear the same claims as the basic product, provided, however. that specific"claims may be deleted if by doing so, no other changes to-the label are necessary. product must remain in the manufacturer's unbroken container. The label must bear the 

### EPA registration number ofthe basic product, followed by a hypen and the distributor's company number. Distributor product labels must boar the name and address of the distributor Qualified by such terms 

### as ·packed 

### for

...,·distributed 

### by

.....; or sold by

..... to showthat the name is not that of the manufacturer. All conditions of

### the basic registration applv equally to distribotor products. 

### It is the responsibilitY of 

### the basic registrant to 

### see that all distributor labeling is kept in compliance 

### with requirements placed on the basic product.
Distributor 

## I W.m',Md to lIlIN/wr our,"oductunde, thq Oi&tribuw('Product Nimw 3pl'ICirrsd.wOVtl, sllhi-cr to tho condftiOfl$ lIPttcirNid on thi# Natictl. 

## • • Oato 

## • •• •• ••



## • < 

## ••••• 

## • • •

, 1ist

EPA Fein' 8570·5 (Rev. 2·921 Provious ed!i.km, IIr(l Ob90lfito. 

# .. . • ••



# .. . · 

# .. 

# ., 

# . •••• 

# ..

# • •

Paperwork Reduction Act Notice 

### The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product 1s estimated to average 15 minutes per response, including time for reviewing the instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the information. Send comments regarding this burden, to chief, Information Policy Branch, PM 223. U.S. Environmental Protection Agnecy, 

## 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (DMB No. 2070-00441, Office of Management and Budget. Washington, DC 20503, Marked"Attention Desk Officer for EPA."


# • 

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# 46

# &

# EPA fTWst bo Unilod Shllo" Enllironmllfll-al Protoction Agoncy Oftico 01 Poslicido Programs IH7505Cl 401 M SPOilt SW Wusnrngton, DC 20460 

## Notice of Supplemental Distribution of a Registered Pesticide Product 

## Instructions

<Ii 

### regisuant has obtained final registration for the basic product. the registrant may 

### then supplementallv 

# I**~:;:~:g~:~;hislher** product. One form must be submitted for each distributor product and must be 

### signed bV the 

# II involvod. 

### The basic registration number and the distributor company number must be shown.

a registrant has 

### a potential distributor who does not have a company numbor assigned, shelhe should have the 

# I**d;SU;~b;'tOr** apply. 

### on letterhead stationary. to the Registration Division to have a number assigned prior to submitting I 

### form to the agency. Notice of Supplemental Distribution must be submitted by the basic registrant. The completed form must have concurrence and signature of both the registrant and the distributor. Product 

### 264-418 

## q ; 51251 Note: Do not submit distributor product labets tbMicproductntlmfl 

## Ethephon for Cotton and Tobacco SF S('I'vices IlP.LP !wand 

### Ethepnon for Cotton

. im:Jud.ZlP CDd.1 

## S,p' 

# SCyvicp" r

# nc '

'i3;)Ji 

# Nodh J1},m 

# 51:; , NorI-h ).,ilfle

# f2lx

# f ,11 ;<, 701.//"1

1. The distributor product must have the same composition as the basic 

### product. and 

### Tobacco

The 

### otStributor 

### product must 00 

### manufactured and packaged'by the same person who manufactures and packages the registered basic 

### product. The 

### labeling for the distributor product must bear the same claims as the 

### basic product, provided, however, that 

### sped'fl,c claims may be de:leted if by doing 

### so. no other changes-to 

### the label 

### are necessary. product must remain in the 

### manufactUrer's unbroken container. The 

### label must bear the EPA 

### registration number ofthe basic product, followed by a 

### hypen and the 

### dlstributot's company number. Distributor product labels. must bear the name and address of the distributor qualified by such terms as ·packed for•.•,"distributed by

.....; or sold by.•.• to show that the name is not that of

### the manufactUlor. All 

### conditions ofthe basic registration apply equally to distributor products. It

### is the responsibility ofthe basic 

### registrant to 

### s.ee that all distributor labeling is kept In 'compliance 

### with requirements placed 

### on the basic product.
Distributor 

## I**~'**

## ••**,,~'"** ro fMlkllt QUf'

### pt"Oduct undtK tJt. Dist.ributwProduct N_ $pM:i1hHi 400_. $UbjBct 

### to thIIc.mditiom:**~1fXI**on thi8 Noticf,. 

## • • • 

## ••

•••• Signature and retia of Diouibotor 

### (Y-'\ 

## • ••••• 

# • • • 

# •• • 

# · " 

# .. IlIgrlHl th,,, t/Hl al$tributornlll1HKl4bove miry disrrilwtlllllld111111 thtt DitrtTibutorProductspilCifiM/**~oVll.** subj«t to th.ctmdfr:m;**~**

## M· this Noticf,. • ••••



### i 

## st
EPA FO'm 8570-5 tRav. 2-921 PrliviouS' edilions "'/11 ",bsoteta. 

# ·

# .. • • •

# • •

Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response, including time for 

## reviewing the jnstructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the information. Send comments regarding this burden, to chief, Information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070-0044), Office of Management and Budget, Washington, DC 20503, Marked·Attention Desk Officer for EPA.·



## •••••• •• 

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# 48 

# ,

,. Al! !nllllucliont< Be-folD 

## ],,) Form (Form
Unitod**S\lllil~** Envilonmcnta! Prot$Cllon Agcnoy Offke of Poslicido Pfogram$ lH7505C) 401 MSlIool SW Wllllhinglon. DC :20460 

# &EPA
Notice of Supplemental Distribution of a Pesticide Product 

## Instructions After a registrant has obtained final registration for the basic product, the registrant may then supplementally distribute his/her ptoduct. One form must be submitted for each distributor ptoduct and must be signed by the distributor involved. The basic registration number and the distributor company number must 

### be shown.**~;::~;~;~;'~~p~:.** a potentia! distributor who does not have a company number assigned, she/he should have the • on letterhead stationary, to the Registration Division to have 

### a number assigned prior to submitting agency.

I 

### Notice of Supplemental Distribution must bo submitted by the basic registrant. The completed form must have

concurrence and signature of both the registrant and the distributor.
of Product CompanyNumber 

### 1169**I----~**

## __**~~_~~_~~** 

## _____**~L-='--_~,--** 

## __________

# I Note: Do not submit distributor product labels lK:r:t1PtDf'i byEPA} Dishibulor Product Nomo

## brand fOI' 

## and Tobacco of Distributor (TYJW: 

### includ.ZIP cod.) 

## Gold Kist, Inc. 

## 't"P.I?Epll [b 

### a: 

## /le.gJ....6tVti?.d ,u,adeu!Q.kh 06 RllOne-Pou..ee.nc 

### Ag Campa-JU( 

## 244 Perimeter Center Park\-/ay, NE 

## P. O. Box 2210 Atlanta, GA 30301
RoadAll

The distributor product must have the same,composition as the basic product. 2. The distributor product Inust be manufactured and packaged by the same person who manufactures and packages the regist8/ed basic product. The labeling for the distributor product must bear the same claims as 1he basic product, provided, however, that specific claims may be deleted if by doing so, no other changes to the label are necessary. The- product must remain in the manufacturer's unbroken container. label must bear the EPA registration number of the basic product, followed by a hypen and the distributor's company number. Distributor product labels must bear the name and address of the distributor Qua!ified by such terms as "packed for

...,ndistributed by

.....; or sold by

... n 

### to show that the name is not 

### that ofthe manufactUrer. 7. All conditions of the basic registrat[on apply equally to distributor products. 

### It is the responsibility of the basic registrant to see that all distributor labeling is kept in compliance 

### with requirements placed on the basic
Distributor 

## •••••• • 

## I"' ••

# "",d to mmlctft ourproductundsr th8iJistribut"rProoucf

# N_ $pVCifiqd#bov",subjt1ct fo fhe canditiolJ8**~ttKJ** "",this "otic••

SignalUlO .,dTitle 01 Disllibulol 

## G0A$- jif-

# d;~r:k~**/?2r?~,.-** ... 

### c":?,.,,?_,,-**~-~** 

### RegIstrant 

## •••••• •••••• 

# •**~OJ·** 

## •••• 

## • 

# •**tJ??~s:~··.** 

## ••••• 

# • •• 

# •

•••• (aflftHI th.t thlt dl$tributor namedobevlt nmy

### dwtribute andsoli thl1 Dis[ributor Productspoci(iBd.wav", wbjuct ro the 

### ccndj60;r,·4ntcirHHfon this Notic#. •• •

EPA Form 8570-5 !Rllv. 2·92) Previou$ editions IIro obsolele.

# • •
Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response, including time for 

## reviewing the instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the information. Send comments regarding this 

## burden, to chief, Information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 401 M Street, S.W

.. Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070-0044). Office of Management and Budget, Washington, DC 20503, Marked'Attention Desk Officer for EPA.'


# • 

# •

• 

# •

• • 

## •• • ••••



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# 50'I Unilcd Stales Environm6fllal Protru::lion Ag&flcy Office of Pc!ticido PrOijfl.llllS {H7505CI 401 M Siroot SW W<lshinglon, DC 20460 

# &EPA Notice of 

## Distribution of a Pesticide Product 

## Instructions
After a registrant has obtained final registration for 1he basic product. the registrant may than supplamomally dis1ribute his!hQr product. One form must be submitted for each distributor produCt and must be signed by the distributot involved. The basic tegistration number and the distributor company number must be shown.**Iflfi~a;;;:~~i:~;"an~,**

### has a potential distributot 

### who does not have a company number assigned. shelhe should have the d apply. on letterhead st31ionary, to the Registration Division to have a number assigned ptior to submitting form TO 

### the agency.

I 

### Notice of Supplemental Distribution must be submitted by the basic registrant. The completed form must have

concurrence and signature of both the registrant and the distributor.
Number



### Note: Do not submit distrIbutor product labels Product {basic product nlJffl#1llCC6Pted by EPA} 01$lribulor Producl 

### Name 

## W A¥<-\"c\<.?\'c.\..D**'B'('c;._~** 

# ?\Zc?

NamG ..,dAddr&"

### WA.vt'~~';;::-\E\....O 

# ?m, ?,...:9

..... At 0 \.)'"

## ~ 0

........

## <?~~ 

# ;\\-.{
nlNldA11 ComIItiom

_ SignIng



### 1. The distributor product must have the same composition as the basic product. 

### 2. The distributor product must 

### be manufactuted and packaged by the same person who manufactures and packages tho registered basic product. The labeling for 

### the distributor product must bear the same claims as the basic product. provided. however. that specific claims may be deleted 

### if by doing so, no other changes to the label are necessary. The 

### product must remain in the manufacturer's unbroken container. The label must bear the EPA registration number of the basic product. followed by a hypen and the distributor's company number. 

### 6. Distributor product labels must bear the name and address of the distributor qualified by such terms as**~packed** 

### for

...."distributed by

...·; or sold by"

..**~** 

### to show that the name is not that of 

### the manufacturer. 

### 7. All conditions of the basic registration apply equally to distributor products, It is the responsibility of the basic registrant to see that all distributor labeling is kept in compliiimce with requirements placed on 

### the basic product.
Distributor 

# I'W''''',Md •••••• • to mMkotour productunder t'1IIDk;ttibutorPrcduetN_sp«:ifHWabovu, subject to tlw conditiOlt$ .J'tICI'fiedon this Nqticfl. 

## • • • • Tido ofOimibutof



# --

, Registrant 

### •••••• 

## •

• 

# •• •• •

•••• fI{Jf1Hl that tho dmtributornamod """"m" 

### .';SUm.,. andsPIItheDitJtnoutor

### Producrt'ipacifWd libow, st/bjl1-ct to tho**c(J(lrfl,&¥~rfi8d**

### on 

## •• •

8570-5 IRev. 2-921 Prllvioos odi!ioo$ 4ro oblloleto.

# --_

......

# _-_._------------- 

# • •

Paperwork Reduction Act Notice
The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response, including time for reviewing the instructions, searching existing data sources, gathering and maintaining the 

### data needed, and completing and reviewing the information. Send comments regarding this burden, to chief, Information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 

## 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070·0044). Office of Management and Budget, Washington, DC 20503, Marked"Attention Desk Officer for EPA."

• • •• 

## • ••••



## • 

## • • 

## •••••• 

## • •••• 

## • •••• •••••• 

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•

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# 52 

# • 

# •

• 

# •

## ----------------

I, Cynthia Giles-Parker, Product Manager, Team 22, Fungicide 

## Branch, Registration Division, Office of Pesticide programs, Office of Prevention, Pesticide and Toxic Substances, United States 

## Environmental Protection Agency (EPA), certify that the pesticide product (8) listed below is, as of the date of this letter, a 

## registered product under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) I 

## as amended, and that as such, the 

## product(s) may be sold and marketed in the United States of America as authorized and limited by FIFRA. A true and correct copy of the product label approved by 

## EPA is attached to accompany this letter. Registration of this product (s) with EPA also denotes that the 

## registrant listed below is responsible for ensuring full compliance with all laws of the United States of America, or governing jurisdiction, regarding the sale, storage and/or disposal of the 

## product(s). Further the recipient of this letter is on notice that the status of the 

## referenced registration and/or the accompanying label may change subsequent to the date of this letter. EPA assumes no responsibility to notify the recipient of this letter of any change in the status of the registration(s) and/or the product label for the product{s} listed below. EPA has issued registration numbers for the product(s) listed below to: Aventis CropScience USA LP P.O. Box 12014, 2 T.W. 

## Alexander Drive Research 

## Triangle Park, NC 27709

EPA REGISTRATION NO, ERQDUCT NAME



### 264-418 

## CERONE® 720 

# /j

f 

### .-..J
c , 

# , Cynthia GileS-Parker Product Manager (PM22) Fungicide Branch Registration Division 7505C



# 53

# r--.------ 

# I I IIIn9tructions BIlI",a FOlIO (Form mustbo
United Stst&!! En'l'ironmet\tol Protootion Agency Offico of Pcslidd4 P"'gram!l (H7505C) 40) M Stle"t SW Washin';ltIln, DC 20460 

# aEPA Notice of Supplemental Distribution of a Registered Pesticide Product 

## Instructions
After a registrant has obtained final registration for the basic product, tho registrant may then supplemantally



### i i his/her product, One fotm 

### must be submitted for each distributor product and must be signed by the distributor involved, The basic registration number and the distributor company number must be shown.**Ilffi;a't;;i;~~~;";~,**

### has. a potential distributor who does not have a company number assigned. she/he should have the d apply, on letterhead stationary, to the Registration Division to have a number assigned prior to submitting to the agency. Notice of Supplemental Distribution must be sUbmitted by the basic registrant. The completed form must have concurrence and signature of both the registrant and the distributor,
Numbet of Producl Company Numbet



### Note: Do not submit distributor product labels I1f**n~itJterod** Ptiiduct lbasicproductnlM'UlllCCltpttHIby EPA} Ohltributol P,oduct N$no 

## PREP brand

Calarcor Inc. 

## P.O. 

## Box 727 

## Corcoran, CA 93212

## for

Tho 

### distributor product must have the samO composition as 

### the basic product. 

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The distributor product must be manufactured and packaged by the same person who manufactures and packages the registered basic product. The labeling for 

### the distributor product must bear the same clairr:ts 

### as the basic product, provided, however, that spocific claims may be,deleted if by doing so, no other changes to the label are necessary, The product must remain in the manufacturer'to unbroken container, The label must bear the 

### EPA rogistration number of the basic product, followed by a hypen and the distributor's company number. Distributor product labels must bear the name and address of the distributor qualified by such terms 

### as "packed for".,"distributed by,.,M; or sold by"," to show that the name 

### is not that of 

### the manufacturer. 

### 7. All conditions ofthe basic registration apply equally to distributor products. 

### It Is the responsibility of the basic registrant to 

### see that all distributor labeling is kept in compliance with requirements placed on 

### the basic product.
Distributor 

# I'" ",'"

..tD fTIIHkot I1urprDducrumilllr the DisuibutIlrProduct

### Non,. specirlDd OODVD. wbject to the cDnditions spncifNxi DII thiJ NIlfic". Doh, 

### April 19, 1995 

### Registrant
agme that thtl dhJtributofntunedIJbOvtfmay distribut9 andsell ihg DhtributorPtf)duct3IWCHitidIilbIlvtt. "ubj6cr 

### ro the conditionsspfldlHKllin thm Notice.

EPA Flinn 8570-5lRov, 2·921 editkma IIle**I1b!lo~t(l. -----------------~** **~~-~~**



### Paperwork Reduction Act Notice The annual respondent burden for the Notice of Supplemental Distribution of a Registered Pesticide Product is estimated to average 15 minutes per response, including time for reviewing the jnstructions, searching existing data sources, gathering and maintaining the 

### data needed, and completing and reviewing the information. Send comments regarding this 

## burden, to chief, information Policy Branch, PM 223, U.S. Environmental Protection Agnecy, 401 M Street, S.W., Washington, DC 20460; and to Paperwork Reduction Project (OMB No. 2070-0044), Office of Management and Budget. Washington, DC 20503, Marked "Attention Desk Dff;cer for EPA."

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# • UNITED STATES ENVIRONMENTAI. PROTECTION AGENCY 

### WASHINGTON, D.C. 20460



### Ms. Gail S. Powell, Ph.D. Rhonc·Poulenc Ag Company P.O. Box 12014,2

## T.W. Alexander Drive 

## Research Triangle Park, NC 27709·2014 Off

### rce Of 

### PReVENTION. PESTICIDES 

# ... TOXIC SUBSTANCES



### July 7, 1999

EPA FILENO: 264·257,264·267,264·377,264·418.264·498,264·564

SUBJECT: Certification to Compliance with Child·Resistant Packaging Regulations Per PR Notice 96·2

DEAR REGJSTRA'IT:

The Office ofPesticide Programs has reviewed yourvoluntary certifications regarding child·resistant packaging and compliance

## v.ith the standards of40 CFR 157.32 includingthe 

## revised effectiveness standards: in 16CFR 1700.15(b), and [he revised testing procedures in 

## 16 CFR 1700.20 as published 

## in 60 FR37710 (July 21, 1995), Yourcertifications did include a statement describingthe type ofpackage used and itsdesignation using the American Society for Testing and Materials (ASTM) Standard D3475·95 "Standard Classification ofChild·Resistant Packages."

Please note yourchild·resistantpackagingcertifications

## will beplaced 

## in the registration jackets for the above named products. Ifyou haveany queslions please contact me at(703) 308· 7051. Sincerely,

# Z4~/2(,-~ Eugenia McAndrew 

## Technical Review Branch Registration Division



# 56

### r-
. $ dJIJ/j

- 

# \**'II~** 

# RHONE-POULENC**~** 

## CRrCERTWICATION NO PACKAGE CHANGE



# •



# • RHONe-poULENC AG COMPANY


# Child-ResistantPackagi1lgStateme1lt

Date: December10, 1997



## NameofProduct: PREpTM br.md EthephonforCotton and Tobacco

EPA Reg. No.: 

## 264-418 Registrant's Name and Address: Rh6ne-Poulenc 

## AgCompany PO Box 120]4, 2 T. W. AlexanderDrive Research Triangle Park, NC 27709-2014

I 

## certify that the packaging used for tillS 

## productmeets the standardsof40 CFR "157.32, including the revised standards in 16 CFR '1700.15(b), 

## when tested by 

## the revised tesbng procedures in 16 CfRI700.20, as published in 60 FR 37710 Ouly 21, 1995).


## Please note thatChild-ResistantPackaging is provided on a voluntary basis only for the 1 gallon (3.7854 liter) alld 2.5 gallon (9.4635 liter) containers.

For2.5 gallon (9.4635 liter): The

## type ofpackage is a 63 mm, one-piece, reclosable, continuously threaded closurewith 

## a localized squeezeforce while htrning, ASTMType 1 Bchildresistantmechanismon an "F" style plastic bottle.

For 19.1Ion (3.7854 liter): The type ofpackage is a 38 mm, one-piece, reclosablc, continuously threaded closurewith a localized squeeze force while tUflling, ASTM TypelBchild-. • •••••• 

## resistantmechanism on an "P' styleplastic bottle. •

Sincerely::-. / )," f

# ~ .. r;' / '// 

# tl

,. /,j II)".'" I ,/,.--,t-<,./**~-,** "**v~** 

# GailS. Powell, Ph. D. SeniorHegistration Ma-naget •••••• 

## • •• • •



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### eox: !alj·!.:;;.- WAlfr)(A:--;CfR 02.1>11; AFS(ARCH 1fl!/ONGl£ PARK, ,.C '71(B·2')\4 (919)549·200) Excellence ifi Pedorrnance 

### Pride mAchrevemenl nHFANA'lICN,\(. raE>'. NurJ!lfB4WJ378---N;SWlf,lll-,CK APC AT? INTERNATlO!{.O,l OI$TRlfjUTlon SEII-f,efS >fLEX NUMtlHI 49W377,MlSW(RHACKAPC lOS 

# 57 

# -

# •**~~~** 

## -------

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# --------

AUG T 1998



## I, Cynthia**Giles~Parker,** 

## Product Manager, Team 22. Fungicide Branch. Registration Division, Office of Pesticide Programs, Office of Prevention, Pesticide and Toxic Substances, United States 

## Environmental Protection Agency (EPA) I 

## certify that the pesticide product (6) 

## listed below is, as of the date of this letter, a 

## registered product under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, and that as such l 

## the product(s) may be sold and marketed in the United States of America as authorized and limited by 

## FIFRA. A true and correct copy of the product label approved by 

## EPA is attached to accompany this letter. 

## Registration of this product (s) with EPA also denotes that the registrant 

## listed below is responsible for ensuring full compliance with all laws of the United States of America, or governing jurisdiction, regarding the sale, storage and/or disposal of the product(s). Further the recipient of this letter is on notice that 

## the status of the referenced registration and/or the accompanying label may 

## change subsquent to the date of this letter. EPA assumes no responsibility to notify the recipient of this letter of any change in the status of the registration{s) and/or the product label for the product{s) listed below. EPA**ha~** 

## issued registration numbers for the product(s) listed below to: Rhone-Poulenc PO Box 12014, 2 T.W. Drive Research Triangle Park, NC 27709-2014



## EPA REGISTRATION NO. PRODUCT NAME

264-418 

## Prep brand Ethephon for Cotton & 

## Tobacco Alternate Brand: Ceronem

..**~~--~~ .~.**  - "-



## ----

# /~/ Cynthia Giles-Parker Product Manager (PM22) Fungicide Branch Registration Division



# 58

# ... /-

# ~ RHONE-POULENC**RH6NE~POULENC** AG COMPANY



### JlIllL,26,199:4



## Ivls. Cynthia**Gile~-Parkt'r** 

### OffiCI..' of**P(~sticjdt'** 

### Frog-rillnS (H7505C)
DOCUlllCllt**rroCt~ssing** 

## Desk (CER'[) L'.s. Envirnnmclltal PruLectinn 

### Agl'ncy 

### RUDm 266A, Cry::.[allvlall 2 1l)2] 

## Jt.'fferson Davis Higlnvily 

# e Arlington, Virgil1.ia 222])2

Re:**CERONI:~'-720,** 

### EPA Reg:. No.: 264-418
PI('dSt' 

### prnvidl' liS with it 

### (l!ftificMp 

### of rl'gisLratioil for the pn.!tiud rdl-'fel1Ced 

### .tbOVt'. Ph'ilSl' 

### lLlclude tht' 

## follmdng iuformation un th\' l'('rtificiltl':


### (1) Rl'gistfalIt:



### (2) ),j,Ulll' 

### uf Ihe Product: 

## Rhc'mr-Pmlit.'uc Ag Compilnr 

# r.o. Box 12014, 2T. 

### W.**AJexalH.h~r** 

### Drive R('seHI'(h Tri'lllgle 

### F,lrk, ;\;Ol'Lh 

### Clrnlina 277Lll}


### CERO!'\l:> 

### 720, EPJ\**J~l'g.** 

### Nu.: 264-11F1 

## (1)**Th\~** 

## phrase ",,:.Hbl.PJ1.!,.;,'J2frd.Y.QUb£.Jlli[f!e!m>.-b: .,,..thattlw product Illay 

## besold dnd 

### tnMkl'Ll'u in the Lnih'li Slates of**Anlt~ri(i'l** 

### for the Wil'S 

### indicdtl'd un 

### Lltt" label."



### A c{lf1Y lIf 

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### lteL'

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• - **RHONE-POULENC**

RHONE-POULENC AG COMPANY



### April R. ]998



## Unilcd**Stal~S** 

## Em**irolllH~'JlIal** 

## Prole!.:)iun Agency OfficL" 

## orpc::.1icidL' Pwgrams DOl.'lImeU1 I'roccs::.iug ])

....s\...( 

## 7505C) 401 M Street SII' 

## Washington 1),( 20460-0001

RE: Fi"JISt-I.K llarYcSl 

### Aid tiJr COllOIl (H':\ 

### Reg. :\n. 26

..k'i64)**C~cJanjljd('** 

### Tcchnicitl 

### (EPA Reg. '-:"0. 

### 2h-l-565 t**~utJ** 

### all Rhuue Poulenc Frhl'phon Product.<. (264-257, 264-163.**~64-:?67.** 

### 26-1- 

### 292. :::64-':>7b. 

## 26'+-377. 26..J.-.l80. 2(,-+--%18,164-51 bnd 11'14-543



## Dear Ms. Gill.'s-ParkL'r.

ThhkUC'f 

## is 10 

## inlimll**~nu** 

## Ihm due 

## 10 n.?l:(':!ll**tlrg~U!iz<Jli0nal** 

## cbJ.J1gt.'s at Rhone Pouknc. I

## will nil longer be handling 

## regislnllion issues on cyclallilid.

..... t:10.']SfI**i~,'** 

## brand 

## f-larvC$l Aid 

## for Collon. or ethephon 

## prodUC1S. \ifr. Warrcn Davis will 

## assunH: n:g.uLHory**rcspollsihiJiti~s** 

### for 

## ryd:.milidt' and FINISI+J.t. He call**b~** 

### r(:uchcu;tt**919~549<:.;**

### 79. \lc :.iick Summa will handk all**~lhl.'pholl reglll(1lD~**  

## isslles. \J

### lek'::> pholle 

## nurnhl.'r is 919-**5..JCJ~2**

### 3**7~.** 

### Pk;rsc .addn:ss 

## all tlnun.' corrcspolKiL-nce 10**~kk** 

### or Warren, YOli 

## sholllJ**~'oniinlll'** 

### 10 USC' 

## the 5;1111(.' mailing address 10 

### reach 

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### Wnrn:n.

1 

### havl.' enjoyC"d 

## )\orkmg**~\j1h** 

## you ill1(1 

### panii.:ularly 

## appn.:cialt: alll)fyvur comribu1inH5 to the FI:\ISI·1 U**r.;~iSJr;lt:un** 

### Ihi" pUil 

### year. 1t;JJl 

### b",**r~<1i.:hed** 

### al 

### 9!9-5-19-::'687**if~(lu hil\~~** **~Uly** 

### qUi.:i->tinn

...



## Gail S, PO\\t:l1. Ph.D. Senior Regislration**~Ialtagcr**

PO&JX**IX:~** :tT'.-, .\\[:'<.AN";i-.?;:':"-" f.1£'5EARCH**WIA!'Gt~** ,',ofOr; I. C**:::'7;~<'(;1~** (91<j)**~49<?;X:()** 

### Excellenc"! 1!1 

### r>erfcJ!!nance Prrde (f)

### Achievement IIHEf1IiA,IONAL Tf-fX Nc)',!"fH**~7.B'7ii·A("'·,1,r** Rt!:IK :,pc i'l7**I~JT(ml<\;iDh';L l<;h~'E'J,r(A'**  ":(G'd><, 1) LFj !.,lNflUl .1j",:,j/J·/d**,S·.V;~'N** ,,' Ji! ,- ,os 

# 60**----.~**..

# ---------

AHONE-POULENCAGCOMPANY



# • EPA Correspondence No. GSPlethi\J54 September 17. 1997

U.S. Environmental Protection Agency 

## Office ofPesticide Programs 

## (}l7504C) Document Processing Desk 401 M Street SW Washington D.C. 20460-0001

Atttl: Ms. CynthiaGiles Parker(PM No. 22),

RE: Ethephon Oat.Compensation (EPA Reg No.: 264-51 

## I. 264-418 and 264-267)

Dear Ms. Giles**~** 

### Parker.



### 1am 

### attaching (WO 

### letters relating (0

### ethephon datacompensation. These wererecently
sem

## by Rhone Poulenc toMicrofloCompany and Griffin Agricultural Products. 1

## think if is important thatthe Agency is aware that outstandingcompensation COSIS 

### exist. I believe that 

## both companies have cited [he studies in question to supporttheirethephon registrations. I will advise you as soon as a 

## daticompensation agreement is reachedfor these studies. 

# e Ifyou have any questions concerning this maner. Ican

# ~ reached at

# 919~549~2687.**,~.::.~r1'** {91gl54!1-:1!XI 

### Sincerely.

# %J;/~ Gail Powell. Ph.D. 

## RegiStr.1ll0n Manager

IN1£RNATlOf.

__**~,_** . __**~_._** ....... WEflBACKA?CRT? lNT£RNATICh'.£Al O1SHllBunON SfR'IlCES TElEX NUMBER40000n.ANSwtRBACK ;.PClOS 

### Excellence In 

### Performance Pnde In 

### Achievement 

# 61

# • ""RH(jNE-POULENC

RHONE-POULENC AG COMPANY



## Mr. George Thornlon Griffin AgrlcuIrurai Products P.O.80xI847 

## Rocky Ford Road Valdost.GA 31603·1847 September 17, 1997.

RE: Ethephon Data Compensation (EPA Reg No.: 264·511, 264·418 and 264·267)



## Dear Mr. Thornton,

I have attached a list ofstudies and associatedcosts required

## by EPA forethephon reregistration. These studies have been completed sinceourApril 12, 1996agreement. In 

## addition to study costs, we have also includedcosts for adietary risk assessment, petition fees to 

### supponcononseedlgintrash tolerances, andcontract fees incurredin the preparation ofthis petition. Yourshareofthese costsis onc thirdofthe total cost or 

## $157,619.00. These costs were nO! included in ourprioragreement. Please submit paymentwithin 

## 30 days ofreceiptofthis letter. I can be 

### reachedat**919~549-2687** 

### ifyou 

### have questions.

cc: Alan Reade 

## Len Castillo Peg Cherny 

## Jack Boyne Cynthia Giles· Parker (EPA)

# )I;~ Gail Powell, 

## Ph.D. SeniorRegistration Manager

..... r ,,] 

### _)-''''1**;J.~.,F**



### P1 '1**~i,** 

## AI L,,-t

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# 62

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## VJ 

# I::thephon Data Submitted to

# ~t 

# • I; ScplewiJc! 1!J3i

RafDrencif Study Name Subml,rrn>n /

....... M Stl.ldy Tit/o Year ofStud)" MRID D

... SludyCost, SK
MOA VERIFICATION· HUNT, T.W. 

### 1m. 14C'VAUDATIONOF GENERAL METHOD FOR THE ANALYSIS OF 1996 44036001 14-JUN·96 $26,647 POULTA.T1SJEGG ETHEPHON RESIDUES IN AVARIETY OF SUBSTRATES FOR ETHEPHQN IN POULTRY 171-4101 LIVER. STUDY NO. EC·95·327. JUNE 13. 1996.54 PP.**so~** MILLER N.E, AND A.C. UU. 1996. 2·HYOROXYE7HYL PHOSPHONIC ACID (ETHEPHON 

# ,- 43991301 ZZ·APR·9fj SS3JlOO ADSORPTlON/DESORPTIQN METABOLITE) ADSR:OPTIONIDESORPnON STUDY. RPAC. STUDY

### NQ. eC-95-314. APRil 163·1 

### 11,1996,232PP.
RISK ASSESSMENT KIDWELL, J. 1996. ETHEPHON ACUTE DIETARY EXPOSURE ASSESSMENT. GUIDELINE 1996 

### 44100203 26·AUQ·96 52,099 NO. NA. TAS, INC. STUDY NO. ETHEPHONOO..(li.AlJOUS721, 1996,37PP.
ACUTE NEUR070XICITY BEYAQUTY, P. 1996. ATIME OF PEAK EFFECTS STUDY OFA SINGLE ORALLY 1996 440006-01 29-APR·9fi 81-8 ADMINISTERED DOSE OF ETHEPHON IN RATS. PROJECT 10 97411, BID·RESEARCH LABORATORIES LTD., APRil 19, 1996, 132 PP
ACUTE NEUROTOXICITY BEYROUTY, P. 1996. AN ACUTE STUDY OFTHE POTENTIAL EFFECTS OF ASINGLE 

# ,,.. 44000602 2!:h·\PR·96 $149.280 61-8 ORALLY ADMINISTERED DOSE Of ETHEPHON, TECHNtCAL GRADE, ON BEHAVIOR AND NEUROMORPHOLQGY IN RATS. PROJECT 1097412, BIO-RESEARCH LABORATORIES LTD" APRIL 19,**19~,** 569 PP. SUBCHRONIC BEYR04TIE, A. 1997. A2·WEEK RANGE·FINDING TOXICITY STUDY 

### ofORALLY 1997 44283001 23·JUN-97 NEUROTOXICITY ADMINISTERED ETHEPHON TECHNICAL GRADE BASE 250 IN RATS. GUlDELINE NO. NA. 82-7 BIO RESEARCH LABORATORIES. PROJECT 10 97453, APRIL 28, 1997.
sueCHRONIC BEYROUTIE, A. 1997. A 13·WEEK STUDY OfORAllYADMINISTERED ETHEPHON 1997 442B3002 23·JUN·97 $218,006 NEUROTOXICITY TECHNICAL GRADE BASE 250 ON BEHAVIOUR, NEUROCHEMISTRYAND 82·7 NEUROMORPHOLOGY IN RATS. GUIDELINE NO. 82·7. ClINTRIALS BIORESEARCH LTD PROJECT 1097414.APRIL 28, 1997.
PERMANENT TOLERANCE PETITION FEES FOR CHANGES IN ETHEPHON TOlERANCES 1996 l1-SEP·9I) $8,325 ON MILK. MEAT, AND EGG 199$, FOOD QUALITY PROTECTION ACTt PETmON FOR ETHEPHQN TOLERANCES; 

### ,goo 18·NQV·96 $5,440 AMENDMENT TO ETHEPHON COTTONsEEOIGINmASH TOLERANCE -REVISED SECTION FAND G. NOV. 19,1996. PREPARED BY CHARLES, CONN, AND VAN GEMHART.

T""" $472,857 Development SlwIro

.. TO"'1 +3 $157.619



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# •



# • RHONE-POULENC AG COMPANY


## Mr, CEFormby MicroFlo Company P,O, Box 5948 Lakeland, Florida 33807-5948 September 17, 1997,

RE: Ethephon Data Compensation (EPA Reg No,: 264-511,264-418 and 264-267)

Dear 

## Mr, Formby,
1have attached a ii$t 

## ofstudies and a.<;sociated costs that were required by 

## EPA for etbephon reregistration after ourMarch, 1995 Ethephon Data Compensation Agreement. These studies were required by EPA in an April 28. 1995 data call in, Microfloreceived the same data 

## call in, In addition to study costs, we have also included 1) costs for a 

## dietaryrisk assessment, 2) petition fees to support apetition to 

## increasecottonseed and establlsh gin trash tolerances. and 3) contract fees incurredin the preparation ofthis petition, The April 28, 

## 1995 Ethephon Reregistration Eligibility Decision specifiedthat these tolerance changes wererequired. All ofthese costs have been incurred sinceour prioragreement. Your share ofthese costs is one third ofthe total cost for all studies or 

## $236,146,

There is currently an eye irritation study in progress to suppanreregisrration of2 lb ethephon enduse products. This was also a requirement ofEPA's April, 1995 datacall in. Anticipated stUdy cost is approximately $2,200. Your share will be halfofthe final cost. We will 

## bill you 

## faT this in 1998 when the study is submitted to

## EPA.
Please submit payment within 30 days ofreceipt ofthis letter. Ican be 

## reached at 919·549·2687 if

### you 

### have

## questions.

cc: Alan Reade 

## Len Castillo PegChemy 

## Jack Boyne CynthiaGiles- Parker (EPA) Sincerely,

# ~/Zd( Gail Powell. Ph.D. SeniorRegistration Manager

_I ,,' ,'.,.


### , 

### I

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RehlrllllflC. Study »ame**tGu~l1ne** StudyTitle

MOAVEA1ACATlON • HUNT, T.W. 1996. 14CVAl1DATION OF GENERALMETHOO FOATHE ANAlYSIS OF POVlTAX1SfEGG ETHEPHON RESIDUES IN AVARIETY OF SUBSTRATES FOR ETHEPHON IN POULTRY 171·4101 UVER STUDY NO, eC·95-327. JUNE 13. 

## 1m. 54 PP.
RESIDUE-CROP FIELD SEE, R.M. 1995. "MAGNITUDE OF RPA·9094f.iAND ETHEPHON RESIDUES INION seeD TRIALS COTTON RESULTING FROM FOl1AA APPUCATION OF 31039B, 1994. STUDY NO, 171-4IKl US94101R, RPAC AUGU$T9.1995, 7MPP. RESIDUE·CROP FIELD NYGREN, A. 1900. ETHREU!lBRAND PLANT AEGUl.ATORlTOMATOJMAGNITUDE OF TRIALS RESIDUE, RHONe,PDULENC AG COMPANY, UAA91E16, JANUARY 25, 1995.207 PP. 171-4(KI 

### SO<l MILLER, N.E. AND A.C. l1U, 1996. 2-HyDfl;OXYETHYL PHO$PHON1C ACID {ETHEPHQN ADSOAPTIONIDESORPTION METABOlITE)ADSRDPT10N1PESORPTlON STUDY, APAC. STUDY NO EC-95-314. APRIL 163-1
RISK ASSESSMENT

ACUTE NEUROTOXICITY Ill·a

ACUTE NEUROTOXICITY 81-8

SuBCHRONIC NEUROTOXICITY 62-1 SUBCHRONIC NEUROTOXICITY
•N 1',I996,232.PP, KIDWELL, 

### J. 19\Nl. ETHEPHQN ACUTE DIETARY EXPOSURE ASSEsSMENT. GUIDEUNE NO. NA. lAS, INC STUDY NO. ETHEPHON 96·01 AUGUST2-1, 1996, 37 PP. BEYRDUTY, P 1996, A TIME OF PEAK EFFECTS STUDY OF A SINGLE ORALLY ADMINISTERED DOSE OF ETHEPHON IN RATS_ PROJECT 1097411, ,Blc)'RESEARCH**LABORATO~IES** LTO. APRIL 19, 1996, 132 pp, BEYROUTY, P. 1996. AN ACUTE STUDY OF THE POTENTIAL EFFECTS OF A SINGLE ORAllYADMINISTERED DOSE OF ETHEPI-tON, TECHNICAL GRADE. ON BEHAVIOR AND NEUROMORPHOlOGY IN RATS. PROJECT 10 97412, BIQ·RESEARCH LABORATORIES l TO., APRIL 19, 1996, 5£9 PP. BEYRQUTIE, A. 19'91. AZ·WEEK RANGE-FINDING TOXICITY STUDY OF ORAlLY ADMINISTERED ETHEPHON TECHNICAL GRADE BASE 250 IN RATS. GUIDELINE NO. NA. BID RESEARCH LABQRATOA;IES, PROJECT 10 97453, APRIL 28, 19'91. BEvROUTIE, A. 1991. A 13·WEEK STUDY OF ORALLY ADMINISTERED ETHEPHON TECHNiCAl GRADE BASE 250 ON BEHAVIOUR, NEUROCHEMISTRY AND NEUROMOfIPHOlOGY IN RATS. GUIDELINE NO. 82·7. CUNTRIALS BIORESEARCH LTO

. PROJECT 10 97414, APRIL26, 1997.
PERMANENTTOLERANCE PETITION FEES FOR CHANGES IN ETHEPHQN TOLERANCES ON MILK, MEAT. AND EGG YMfof StI.tcty 

# '99'

'995

1995


# "00

1996 

# '119,

1996

1991 

# "'"

1996 Submlnbn MRIO 

# - Study

## eo",$K
44036001 14-JUN·96 S26.647

43868343 I·HiQV-95 $203,063

43532401 I·FEB·95 $32,496

43991301 22-APR·96 $63,000

44100203 28-"UG·96 $2,099

44000eOl 29·APA·96

44000802 29·APR-96 $149,2&0

44283001 23·JUN·97



### '4283002 23·JUN·91 $218,066

11·SEP·$6 $8,325



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# -**~** 

## - RHONE-POUlENC AG COMPANY PO BOX 12014, 2TW. ALGXANDER**[),.'~IVE** RESEARCH TRIANGLE PA"o.tf. N C. 2770(0 

### page



### ,,'

## O'l 

# Ethephon Data Submitted to

# E~

R"tOf'fI(1ce Study Name fGWdeUne S1udy TIIII
1996. FOOD OUALITY PROTECTION ACTI PETITION FOR ETHEPHON TOLERANCES; AMENDMENT TO ETHEPHON COTTONSEEDfGINTRASH TOt.ERANCE ·REVlSED SECTION FAND G , NOV. 19,1996. PREPARED BY CHARLES, CONN, ANOvAN GEMHART. 

# •

Vear 

### ot Study 

# '996 17September 

### 1997

MRIO Submission 

# ""Ie

18-NOV·96

Total DevelopmentShiite '" Total 

### +3 Study (;(at, $K
$5,440

$708.438 $236,146



## O'l

. - - - - - - - - - - - - - - - - . - . - - ••.........- ••.•.... - . - . - . - ..•.. - .. - ... - .. - - ...•.. - ...- .. - . - . - - - . - . -**AHONE~POULENC** AG COMPANY 

### PO BOX 12014, 2TW. ALl;XhNDEil C;;r/E RESEARCH TRIANGLE PI.r.I:, N.:: 27703

.-- - 

### P_ 2



# ."

# • SEP 23 1997

I, Cynthia Giles-Parker, Product Manager I 

## Team 22. Fungicide 

## Branch, Registration Division, Office of Pesticide Programs, Office of Prevention, Pesticide and Toxic Substances, United States 

## Environmental Protection Agency (EPA), confirm that the pesticide 

## product listed below is. as of the date of this letter. registered with EPA under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended, and that accordingly, the product may be 

## sold and marketed in the United States of America as authorized and limited by FIFRA. Registration of this product with EPA also denotes that the 

## registrant listed below is responsible for ensuring full compliance with all laws of the United States of America, or governing jurisdiction, regarding the purchase, sale, application, use, storage or disposal of the product. Further the recipient of this letter is on notice that the status of the referenced registration may 

## change after the date of this letter. EPA assumes no responsibility to n9tify any recipient of this letter of any change in the status of the registration listed below, and advises the recipient of this letter to request that the registrant provide this information if the status of the registration with EPA should change. EPA has issued registration numbers for the product listed below to: Rhone-Poulenc Ag Company P.O. Box 12014, 2 T.W. 

## Alexander Drive Research Triangle Park, North Carolina 27709 

## EPA Registration Numbers
264-418 

## Name of Products**CERONE~** 

### 720 

## Cynthia Giles-Parker Product Manager (Pf.122) Fungicide Branch Registration Division (750SC)



# 67,..---...**~ .~** **.~** ..

### - 

## -- -

# ~ RHONE-POULENC

"



### RHONE·POULENC AG COMPANY



## July 22, 1997



## i\4s, Cynthia Giles-Parker Office ofPesticidePrograms (H7S0SC) DocumentProcessing Desk (CERT) 

## Us. EnvironmentalProtecnon Agency Room 266A, 

## Crystal Mall 2 1921 

## Jefferson Davis Higlnvi.\}' 

# e Arlington, Virginia :22202

Dear Ms. 

## Giles-Parker:



## Re: CERONE" 720 • bl'A Reg. No.: 264418 "



## Please

## provide us 

## \vith**thret~** 

## (3) 

## certificates oi

## registration for the product reierenced above Please 

## inc10de the following information 

## onCilch cernficate: 

# cr) RegIstrant: Rh(me-Poulcnc Ag

## Compall)' P.O. Box 

## 12Ul4,:2 1'. 

# w. Alexander

## Drive ResearchTriangk Park, NorthCarolina 2770tJ



## • (2) Nameofthe Product: CERONE»720, EPA Reg. No.: 264-418
(3) 

## Thephrase within 

## the bod\' of the parabTfaph: "

...

## that the product may be sold 

## and nnrkcted i!1 

### t1');!**Unit~d** 

## St:ltc:, of ,A,rriCri([l 

## for the**\lS,,:~ ;,-,dic'll(:,-~**  tin 

## \l,t:' 

## i;;bt>L**PJ,!~se** 

## contact me at (919) 549-2112 shollid YOIl 

## have 

## tiny**qUl~stions.** 

## Slllccreiy,


## !


# -

Judith 

## L. 

## Moore Registration Document"

## Spedalist

\-":; "'(.if**1~01.1. ~**  r .'/1 ",Le;'''1jDEH "",;[ "tS[AFCI"**F{i'~I,(;_f** "'MY. II::**~7**..,-,·1 :.;,'!**I("'~-'** eot.c..:;.tvc, rllfRJ'lnTI:)l,N )[- Fi. '1' I'L'FR -"_.) ;:,7,., A'J,,".','(;i'U/.'::" <'<PC 1"17i' ,'U[WL:":,CjA;**;:;·~r~;',i'J;-,i3,' "'S'.'f·,~:';**  ""-c.,-,- r;cJ".'""Ul ,F'TXI**;,·,'·;~','.'Ui"i;L"** "P:" I::;',; 

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### in PetfO/!ll3N:fJ 

# 68

# ,---------------**~-~~ ~~** 


### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460



## Gail Powell Rhone-Poulenc Ag Company P.O. Box 12014 Research Triangle Park, NC.27709 

## Dear Ms. Powell: 

# SEP 23 1997 OFfICE OF ?AEVHITION. P'ESTlCIOES AND TOXIC SI.)BSTANCES



### Subject: PREp!!" Brand Ethephon for Cotton and Tobacco EPA Registration Number 264-418 

# e Your letter dated August 14, 1997



# • The labeling referred to above, submitted in connection with 

## registration under the Federal Insecticide, Fungicide, and Rodenticide Act, as amended, is acceptable. A stamped copy is enclosed for your records. Sincerely yours,

Cynthia Giles Parker Product Manger (22) Fungicide Branch Registration Division (H750SC)



# 69

# l brand 

# Ethephon FOR COTTON AND TOBACCO
For Commercial Use Or Agricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: Elhephon (2·ChlOroethyl) phosphonic acid'

............................."

.........................55.4% 

## INERT INGREDIENTS:

...........................................................................................................................44.6% ·This product contains 6 pounds ethephon percalion. 

## EPA Reg. No. 264·418 EPA Est. No. 264-PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no ontiendo la oliquela, busque Ii 

### alguion para quo $0 lit oxplique a ustod on defaUo. (M 

### you do not undGrstand Iho label, !lnd someono to explain it 

### 10 you in detaiL) 

### For MEDICAL And TRANSPORTATION Emergencies 

## .o..ti.L..Y. Call 24 Hours A Day 1-600-334-7577

# ~~_________________

# F~o~r~p~R~O~D~U~CJI~U~S~E~1n~f~o~rm~.~t~lo~n~C~.~I~t~1~-8~O~O~·~33~4~·~97~4~5~________________ _ Tho use 01 fhis producf lor a varioty 01 plant growth rogulalion uses are prOlocted by Uniled Slates and loreign patents including U.S. Palont 4,240,819. No license is granlod 10 uso this product in counlri&$. olhor than the Unitod States or lor any use nol contemplated by Ihis laboL Uabilityfor palent infringement may result lrom use orsale of Ihis product oUlside Iho**Un~od** Slales. 

# FIRST AID IF IN EYES: Hold oyeHds opon and flush with a gonfle slream 01 water lor at loast 15 minules. Get medical altontion, preferably an ophlhalmologlst. IF ON SKIN: lmmedialely wash skin with plenty of soap and wale" Get medical anenlkin. IF SWALLOWED: Do not induce vomiling. Promptly drink a largo ,quantity of milk, egg whites. getatin solution or 

### if thes", aro not available, drink large quantilies 

### ot wator. Avoid alcohol. Call a physician or Polson Conlrol Cenler. NOTE TO PHYSICIAN Treal symptomatically. Consideration should be given 10 the possibility that overexposuflil to malerials other Ihan Ihis produci may have occurred. No sp4cific anlidote is available. Probable mucosal damage may conlraindicate the use 01 gastriC lavago.



## eJANGER HAZARDS 

# PRECAUTIONARY STATEMENTS
TO HUMANS AND DOMESTIC ANIMALS CORROSIVE. Causos irrovorsiblo ey'" damage and skin burns. Harmlut if swallOwed or absorbed through skin. Do not gol in DYOS, on skin or on clothing. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Applicators and olhor handlers must wear coveralls ovor short-sleeved shirls and shon pants, chemical resislanl gloves (such as**N~ril&,** Butyl, Neoprene and/or Barrior.Laminalo), chemical-resislanl tOOlwoar plu:: socks, pJoteclive oyewear, chemical·resistanl headgearfor overhead oxposure and chemical·resistant apron whon cteaning equipment or mixing and loading. Discard clolhing and other absorbenl materials Ihat havo been drenched or heavily contaminated with this products concentrale. 

### Do not rouso them. Follow manufacturor's instructions lor cleaning/maintaining PPE. II no such instructions 

### tor washables, use dotergenl and hot water. Keep and wash PPE soparately from olhlH laundry.

. When handlers use closed syslems, enclosed cabs, or aircraft in a mannor rhat me!)ls Iho requiremenls lisled in**\h"·~er** Protoction Standard (WPS) for**agricu~ural** peslicides 140 CFR t70.240 (d) (4-6)], tho handlor PPE raquiremenls may be re£M;et; or modilied as speciJied In Ihe WPS. • •••••• 

## • 

## •• • • 

# ACCEPTED

SEe 22 i997 • • ••••

## •• •••• 

# · " 

## " 

# .

• 

## • •• •• •

•••• ••• • • •



## ••



# 70 •••••• 

## • •

•• 

## •••••

• • •••••

## User Safety Recommendations**Us~rs** shouldwash hands beloro oating, drinking, chowing gum, usingtobacco or using the 10ilol. 

### Usars should remove clothing immediatoly 

### if pesticide golS inside. Thon wash body

### thoroughly and put on clean clothing. UsafS should remove PPE immediately 

### aftor handling this product. As soon as possibla, wash thoroughly and chango 'Inl0 cIoan 

### clothing. Wash the outside 01 glovos bolaro removing. 

## ENVIRONMENTAL HAZARDS Do not apply dir&CI:1y to waiar, orto areaswhere $urlaco waler is prasen! orto intertidal aroas bolow tho moan highwator mark. 

### Do not 

### contaminate water whon disposing 01 equipmont washwatofS. 

### Do not contaminate wator used for irrigation or domestic purposes. 

## SPRAY DRIFT Avoid spray drift. 

### Do not applywhon weathor conditions may causo drill, 00 not allowthis product 10 drift on to non·target aroas. Drift may result in iHegal residues or Injury to adjacent crops and vogetatron, in tha lorm of loaf YGllcwing and deloliation. To avoid spray drift, 

### DO NOT 

### apply aerially when wind speed is greaterthan 10 mph orduring periods 

### 01 temperature inversions. 

### USG 

### at larger droplet 

### siuwiR 

### a!$a reduce spray drift. AVOIOINGSPRAY DRIFTATnlEAPPLICATION SITE IS nlE RESPONSIBILITY 

### OF 111E APPLICATOR. Tho Interaction 

### of manyequipment·and·weather·relaled lactors delermine the potontial lor spray drift. The applicalor is responsible for a:onsidering all these lactors when making decisions. 

## _(he lollowing drift management requirements must 

### be followed to avoid olf·target movement Irom 8arial applications 

### 10 agricultural lick:! crops. ThoS(! raquiraments do not apply to loreslry applicalions, public hQalth useS or to applications using dry tormulations. 

### 1. The distance 01 tho outer most nozzles on tho boom mus1 not eXCQed 3!4the length 01 the wingspan or rotor. 2, Nozzles must always point backward parallel with tho air stream and never be pointed downwards more than 45 degrees. Whore slates have more stringent regulalions. they should beobsorve<!. Tho applicatorshould 

### be familiar**w~h** and take intouccount the inlormation covered intheAerial Drilt RedUCtion Advisory below: 

## AERIAL DRIFT REDUCTION ADVISORY (This soctlon Is advisory In naturo and does not suporsodQ tho mandalory label roquiromentsJ. 

### INFORMATION ON DROPLET SIZE Tho most affective way to roduce drill potential is to apply large droplets. The best drill managoment strategy is to apply the largost droplots that provide su!!icient coverage and control. Applying larger droplets reduces drilt potential. but 

### will not prevent drilt 

### if applications are made improporly, or under unlavorable environmental condilions {See Wind, Temperalure and Humidity, and Tomperalur. Inversions}. CONTROLLING DROPLET 

### SlZE

• volume • USe high !low rate nozzles to apply tho highest practical spray volume. Nozzles with higher rated llows produce larger 'roplsts.**~** Pressure· Do not excaed the nozzle manulacturer's recommended

### pr~ssures. For'many nozzlatypes lower pressure produces largor droplots. When hlghortlow rotes aro needed, use higher 

### How rate nozzles inslead of increasing pressure, Numberol nozzles' Use tho minimum numbor of nozzlesthaI provido unilorm coverago. Nozile Orientation

- Orienting nozzles so that tho spray is released paralled to tho airstroam produces larger droplets than other orientations and is Iho recommonded practice. Signilicant dolicclion trom horizontal will roduce droplet size and incraaso drilt potential. Nozzle Type

- Uso a nozzle typo that is designod for tho intendod application, With most nozzlo typos, narrowl'H Spray angles produce larger droplets. Consider using low·drift nozzles. Solid stream nozzles orianted straighl back produco the largost droplots and the lowest drilt 

### BOOM LENGTH For somo uso patlorns. reducing the- etfoClive boom length to less than 3/4 ot the wingspan or rotor longth**marl~rtl'1fH** reduca drilr**w~hout** roducing swath width. • •••• 

### APPLICAnON HEIGHT •••••• 

# . " Applications should not be made al a height graator than to foot above the top of tho targot plants unle$.$ a groat".'ight is fequiratJ for airera!! salety. Making applications at the iowest hoightthat 

### is sale reduCQ!> exposure 

### 01 droplets to**ovapornt~n** andwind

. ••: ••: 

## •• • •• SWATH ADJUSTMENT •••••• • •••• When applications arq made with 

## acrosswind, Ihe swath will be displaced downwind. Therelore, on tho up and downwind**odg"e~t,Ptt** tiald, tho applicator should compensate lor Ihis displacement by adjusting the path 01 Ihe aircraft upwind. SwatlJ,**ad~1ment** distance**~hould increa~e.**  with incroasing drift potential {higherwind, smaller drops, ete.l. • .:••• 

## ••• 

## • 

# ..



# ..

71**~-~-~.~~~--** ....

# ---

...

### - ....**-~**..



### WIND Drifl 

### potontial Is IowGst betwGon wfnd speods 012· 10 mph, However, many faetors, including droplol sizo and oquipmonllypa dotormino drift potontial at any given spoed. Application should bn avoided below 2 mph duo to variable wind diroction and high inversion potential. NOTE: local terrain can inlluoncG wind pattErns. Evory applicalor should be familiar**w~h** local wind pallorns and how thoy affect spray drift. 

### TEMPERATURE AND HUMIDITY Whon making appfication$ 

### in 

### low rolative humidity, Sq\ up OQuipmont 10 produce largor droplots to compensate for avaporalion. Droplet evaporation 

### is most savor.whon conditions are both 

### hot and dry. 

### TEMPERATURE INVERSIONS Appfications should not OCCtJr during a tomperature inversion bocause drift potontial is high, Temperature Invorsions rostricl vertical air mixing, which causes sma" suspended droplets to remain in 

### a concentratoo cloud. This cloud can move in unpredidabledirections due 10 the light variable winds common during inversions. Tomptfraturo inversions are characteri20d 

### by increasing tomperatures with allitudo aod are common on nights with llmited cloud 

### cover and light to 

### no wind. They begin to lorm as the sun sets and olton continuo intothe morning. Their presenco can be indicated by ground fog; however. 

### if fog Is not prOMnt, inversions can also 

### be identilied by tho movement of smoko from 

### a ground source or an aircraft smoko generator. Smoke that layers and moves laterally in 

### a concontratod cloud (under 

### low wind conditions) indicates an invarsion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing, 

### SENSITIVE AREAS Tho pesticide should only be npplied when the potential for drift to adiacent sGnsitivo areas (e.g. rasidontial areas, bodies 01 water. known habitat for threatened or endangornd species. non·targetcrops) is minimal (e.g. when wind is blowing away from tho sensitive 

# e ueas). 

## USE PRECAUTIONS Do not apply PREpm brand Ethophon lor Collon and Tobacco through any typo 01 irrigalion system. Avoid spray drift to nearby crops asthis product will causo modaicalions in plant growth. Plant injury or reduced yields will result. Mix only tha amount 01 spray

### you 9XpGCI to use each day. 

### Do not allow mixed**~luHon** to stand ovarnighl. 

# DIRECTIONS FOR USE It Is a vlolatlon of Foderal law to use this product In a manner Inconsistent with Its labeling. Do not apply this product In a way Ihat will contact workers or other persons, either dlutcuy or Ihrough drill. Only prolected handl<Hs may be In the araa during application. For any requlremlmts speclflc to your State or Trlbe, consult the agency responslbte tor pesticide regulatlons. Read entire lab.1 betore using this product.

Usethis inaccordancewith its labeling and with the Worker Proteclion Standard,40 CFR part t70. This standard contains for protection 01 agricultural wolkers on farms. lorosts, nurseries, and greenhouses, and handlers 01**agricu~ural** contains requirements for training, decontamination, notification, and emergency,assistance. "also contains and exceptions penaining to the statements on this label about personal prote<:tive equipment

## (PPE).·~~:;(~,~~:~:~

# I
and rastrlcled·enhy intervals. The requirements in this box only apply to US9S 01 this product that are covered 

## h

Standard, Do not enter or allow worker entry into treated areas during the roslliC!od-ontry inlorval (REII of 48 hours. Tho REI is 72 hours in areas where average rainfall is less than 25 inchos per year. PPE required lor early entry to troated areas that is permill.od under the Worker Protection Standard and that involves contact wilh anything that has been treatod such as plants, soil or waler 

### is coveralls over Iong·sleeved shirt and long pants, chomical resistant gloves such as ·any waterprool gloves, chemicat resistanttootwear plus socks, and protective eyewear. For overhead exposure. chomical·resistant headgear is also required.



## •• 

# · • • 

## •

•• • 

## • •••••• • 

## • • • 

## • • • 

## •••••• • •••••• • • 

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## ••••• • • 

## • ••••• • •• 

## • • 

## •

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,. •

• •



## •• 

# 72STORAGE 

### Do not contaminate water. food, orfeod 

### by storago or disposal. 

### tf containor is brokon or contonts have spi!lod, tollow aU precautlons indicated above and clean up Immediatoly. Boloro cleaning up, pul on full length trousers, tong sleeved shirt, protoctive gloves, and goggles or lace shield. Soak up spill with absorbent media such as sand, earth orothersuitable material and disposo ot wasta 

### at an approved wasto disposalfacility. PESTtCtDE DtSPOSAL Postlcide wastes 

### are acutely hazardous. Improper disposat ot oxcess pesticide, spray mixture, or rinsato is a violaljon 01 Fedorallaw. 

### If these wastes cannot be disposed 01 by use according to label instructions, contact your Stato Pesticide or Environmental Control Agency orthe HazardousWaste roprosontativo attha nearest EPA Regional Oflicefor guidance. CONTAINER DISPOSAL Triplo rinse (or equivalent) Ihe empty containers. Then olfor for recycling or reconditioning, or punctum and dispose ot in a sanitary landfill, or by incineration or 

### if alJcwoo' 

### by stato and local authoritios, by burning. Ifcontainer is burned, stay oUI of smoke. RETURNABLE

- REFILLABLE CONTAINERS tho container to the point ot purchase or designated locations. This container must only be retilled with PREPl),j brand and Tobacco. 

## DO NOT REUSE THE CONTAINER FOR ANY OTHER PURPOSE. Prior to roliOing, ,,'

## "P'''''I

such 

### as cracks, punctums, abrasions and damaged or 

### worn out threads on closure devices. 

### 00 not Checkfor teaks atter refiWng and bMoro transportalion. If the container is not being



## GENERAL INFORMATION COTTON Afoliar spray of PREPn( brand Ethephon tor Cotton and Tobacco will accelerate opening ot mature unapaned cot1on bolls and enhanco defoliation which can result in earlier harvest with an increased recoverablo yield, PREp!J.I treatment on cotton allows increasod otficiency from 

### a onco<lver harvest. TOBACCO (FLUE-CURED): A foliar spray ot PREprn brand Ethephon promotos early, uniform**"yellowing~** of mature tobacco. PREpThi roducos curingtimo, allowing more etficiont use ot curing barn space. and increased control over harvest schedules. SPRAY PREPARATION Add 

### 112 to 

### 314 oftho required amount ot water 10 the spray tank. Start agitation. Add tho requiroo amount ot PREptJ.1 brand Ethephon. and tho romainlng amount of water. Prepare only 

### as much spray solution as can be used on tho day 01 mixing. 00 not allow spray solution to stand overnight. 

### Do not spill tho concentrated product on spray equipmont, or any airplane par1s. ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY

### OF WATER. Use of a nurse tank Is highly rocommended tor avoiding possible spills of concGOlraled tormulation on spray equipmenl or any airplane parts. _ANK MIXTURES WtTH DEFOLIANTS AND INSECTICtDES

## ~REPl'>I brand Ethephon is compatible with DEFt, FOlEXIJo, Oropp2, Dropp® Uifraw2

,

## Ginslar~2, Harvade3

. Molhyl Parathion, GUlhionl

, and Malathion". PREpm may be applied in sequence or

### as a tank mIxture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow 

### aU applicable use pre<:3utions and rate per acre recommendations on labels of products 

### applied as tank mixturo$ or in sequence with PREP N brand Ethephon. In some cases slight reduction in boll opening responso has been observed whontank mixtls with defoliants were used. Good agitation in the spray tank is essential and 

### a lank mixture should not be allowed to stand without agitation lor more than 

### 5 to to minutes. Read and observe 

### all appropriate labol use directions and prl;;lcautions for the defoliants and insOCljcides used. NOTE: UNDER CERTAIN CONDITIONS. TANK MIXTURES OF PREprn BRAND ETHEPHON WtTH DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH ON HEATINGWill EMITTOXtC CHLORIDE FUMES. 

### DO NOT

### MIX PREPn( BRAND ETHEPHON 

### WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OFTOXIC FUMES. EQUIPMENT CLEANING 

## ••• 

## • ••

••• Bocausa ottha acidic natur& 01 this product, prolonged oxposure to spray deposit will damage acrylic plastics. certain pallll.,..••• 

## • •• metals. : •••:. • • Rinse thoroughly with a detergent and wat!)r all exposed acrylic**plastk:·typ~** materials (e.g., aircraft windshields), llnd paintod**~~** within an hour after exposuro to spray doposits. • ••• • • •• At the end 01 each day, rinse thoroughly with a detergent and water aU tho metal parts of the aircraft and th·;

### a;socjate~.pr~ 

# .. 

# . . .... Gqulpmont exposed to the spray depoSIts. • •• 

## •• •

•••• ••• • 

## ••

••



# 73

## COTTON

USE 

## EXPECTED PREprn 

# ONE MINIMUM APPLICATION 

### CONDITIONS 

### RATE 

## GALLON SPRAY TIMING 

# ::EEfT';**~g~~~A~~** ILBS A.1. Acr•• 

# IAir·

..• 

### PREpnt Hot 

### and dry 80°F 

### or 

### 1113 1.0 6 Apply whon the numbor**~I** 

### Boll Opener·· highsf 

### mature unopened**bOIlSt~i:** 

### Dry and 75 to GO"F 

### 2 1.5 4 10 2 sufficient to produce ,:10;' desired crop. See below Cool but abovo 65°F 

### 22I:J 2.0 3 

### lesl 01 boll maturity,

or 

### Treatment**unilormIY.,~~ens** Rook coHon bolls 710 14 days earlier. PREp'N + 

### High soil molSluro 

### 113 0.25 2' 

## to 5 Apply 4 to 7**days~~~'I~~~t~** 

## FOLEX· or 

### PREPnl boll Defoliant Tank High fortilify 

### IDvel application. To b9 used

# as Mix··· 

### a**sequ9ntiallr9almen!.~it~:** 

### or 

## nm**0~~C8orpREP~boli** 

# IRook coHon ·PREPl'1I+ Oropp High soil moisturo 

### 113 0.25 

### 24 10 3 Apply 4 

### to 7 days_**£,~jO! t~**  

### Dotollant Tank High fanility leval 

### PAEPl"d boll



### Mix··• Rank cotton 

### application. To be us.ad**_~s** 

### a sequontialtreatment with, not in place 01 PREpm boll
Pro·Condltioner Hot. dry. abovo 80¢F 

### 213 0.5 12 Apply 

### -4 10 7_d,ays prior to tor Defoliation 

### Cool. above**65~F** 

### 1 113 1.0 6 

### 10 2 defoliant.**._!~~** 

### or crop I i dOlorioration of bollom crop Rank colton and allows lor oartier

• For bost performance. by ground or air applicalion, choose oqUipment and spray volumes that 

### will insurD uniform coverage 01 foliago

and bolls

. •• Pretreatment With Defoliants Prior fa PREpTlI brand Ethephon Boll Opening Treafment: II the collon is overly rank or laying down in lhe middies and good spray covorage 01 tho bolls with PREPw IS diflicult, a pretreatment wilh

• dololian!s will be 

### us.fulto improve boll coverago with PREprn. Use dosago rates 01 PREPl)l recommendod for boll opening, Road and observe all appropriate label use direcfions and procautions for Iho deloliant used

.

.... Can use up to full label rafe lor each product. -.

ouo 

### In Calilornia and Arizona use a volume of no lass than 5gallons per acre lor aDdal applications. Bon Maturity A boll is 

### maturo when 

### i1 is too h3Jd to bo 

### dented whon squoozod between thumb and lingers. too hard to be sliced with asharp kniht, and when tho seed coat bocomos light brown in color. Use Limitations Do not exceed a maximum ot 2.0 lb. ethophon activo ingredient por aero por year through combinod or ropoa:ted usos ot any ethephon products. Boll Opening: Do not tank mix PREprn brand Ethephon with a desiccant if the conon is to be spindle harvesfed. Pre-Condition for Defoliation: Do not tank mix PREpN brand Ethephon with dosiccants unloss plant d&siccation.i$ r,quired. Do not use a dololiant before there is sufficient mature unopened bolls 10 produce the desired yield (see General IrffOU1lfifon section on how to test for boll maturity. 

## • •••••• DO NOT APPLY PREpn< BRAND ETHEPHON IF RAIN IS EXPECTED WITHIN 6 HOURS. Rainfall within 6 Mlllrsof.applica¢m

### Iflal reduco product performance. :..... • •• 'O •• 

### Do not plant another crop within 30 days alter treatment. Sma" grains planted earlier than t month or**intorcr~~d:'lith** 

### the 

## &:.0011 crop to which PREpm will 

### be applied may 

### only be used as cover crops and 

### may not be harvested for food or+Hdo.**PREa~tIll**

### ..y cause yellowing and growth inhibition of treated small grains, • ..:••• WHEN TO HARVEST COTTON : •••• 'O'O •• 

### Do not harvest collon soonerthan 7 days after atreatment with PREpm brand Ethephon, 

## ••• 

# • Ob$orvt;) the troated crop and harvest whon optimum boll opening has been roached. Too early haNost might roduce'u¢luli advantage 01 tha troalment and too late a harvest 

### may result in roduced quality and loss 01 lint which 

### will drop from the plant. 

# 74**---~** -----

### Crop



### Over-Tho-Top Application 

### PREprn Plnts/Acro



### 1113

I 113 - 2213

USE LIMITATiONS 

### 50

40 

# TOBAcco ue-Cured 0

Specific Directions

Use drop nozzJ€!$. Choose TG or 00 spray lips designed to apply 

### 50

- 60 al 35·40 psi and at tractor spoed of 2-3 mph. Use

### 2~'~2>~'P;'**~~iw;** ono on 

### each side ofthe row dropped low enough to direct tho tho I to be ripened and harvested. Thorough spray a diroctod spray, be sure to halVest all loavas romaining on tha stalk are maturo. ensure 

### remaining loavos are malure, tesl spray $Ovora] tobacco plants as doscribGd undertho section ·Proper limo of Trentman!.M Usethe lower rale in a normally mature crop when experience Jnd'icaies Ihat m'fnlmum riponi"9 

### Inducement is requirod. Use the higher rate when tho crop is 

### heavy and has a tendency to be**mor~** rank or when temperatures oro Iowor than normal. Always tGst spray to determine if the tobacco is mature enough to r€!Spend to treatmont with PREplj,f Apply over-tho-top PREPw spray as a line mist using throe nozzlos (ono nozzletips tho comer of tho plant, and one on each side) so aU loaves arecovered , similar to the

.. of systemic sucker J


### Do not apply PREpTH brand Ethophon to immature leaves asthis can result in unsatisfactory coloring, woightloss and redUC6d leaf qualify. 

### Do notallow tho crop to over ripon in tho liold 

### OIlier using**PREP~M** brand Ethopoon. since this may causo some reduction in yield and quality. 

### Do not treat before anticipated major storm which could prevent harvost and resutt in crop loss. DO NOTAPPLY PREpThI BRAND ETHEPHON 

### IF RAIN IS EXPECTEDWITHIN 

### 6 HOURS, Rainfall within 

### 6 hours ot application may reduce product performance, 

### 00 not use PREP'l>( 

### brand Efhophon with additives other than recommended on this label. 

### 00 not planf another crop within 

### 30 days altertreatment 

### Do not exceed 

### a maximum of 

### 2 Ibs othophon activo ingredient per acre per year through repeated uses of any ethophon produdS. APPLICATION TIMfNG Succoss1ul rGsults with PREpn! brand Ethaphon call for troatman! when leaves rue mature, not ovorly rank green when sprayed, To .-easily determine the proper treatment timIng and the numbor ot leaves per stalk ready for harvost, test spray several planfs in mora**~an** onO; location in each liold and observe Ihe reSponse. Mature leavils will begin to yellow in 

### 24 to 

### 72 hours. Test loavesthai**fa~** to yellow in 

### 72 hours ruo not mature and aro not ready for PREprn troatment. Wait 

### a few days to permit further nafural maturing, thon make anofhet test spray or Mmaturity" check. To avoid quality loss and or po!/.siblo leaf drop, harvest any yollowGd leaves prior !o application. Use lower rates under most conditions. limit use

### of higher rates to cool (belowG5F at the tlmo01 twatmontj stow ripening conditions. When you have conlirmod thtl desirad number of leaves pi1r plant that wiD color, you can delermine the number01 acres to treat in order to fill the barn. Propare your tost spray by mixing one teaspoon of PREpn< brand Ethephon in t quart of water. Spray each test plant wilh aboUl f oz. 

### ofthis mixture. covering all leaves with a fine mist. PREprn will not color immature sprayed leaves. WHEN TO HARVEST All mature, sprayed leaves

## wm begin to color within 24 to 

### 72 hours atter PREprn brand Ethephon application, The yellowing process is wealher dependent; cool weatherwill delay, while hot, sunnywealher can speed upthe process. Harvell troated tobacco when leaves have reached the desired color 'Intensity. 

## ••• Harvost can commance 48 hours after PREpm brand Etht'lphon application. To datermine harvest timing and**avd\Q~lIty** loss or leat drop, closely monitor treated crop and weather conditions. • 

## •••••• CURING PREpN BRAND ETHEPHON TREATED TOBACCO •• :. : Curing procedures are as much an art as a scienco and each cure must be judged on the basis of tobacco**cond~M,·ltltarval Qi~t**  treatment and harvGst, weather and type of curing facfHty before prescription temperature and ventiJation.lc/aedulos c"'l. established. To obtain maximum quality, care must be taken to observe and conlrol tho curing process**closely,~ly duri~t**  a late ·coloringM and early ·dryingM stages of tho leaL ••• •• 

## • ••••• PREPTh{ brand Efhephon tr&atod tobacco will have started tho coloring process whon harvested, reducing thq,tirTVI.roquirod in 1M coloring phaso of curing. Treated tobacco should be dried laster. II tobacco loaves are green or contain somo gtmtmon harvosted. 

### it may be necessary to color thom for a 1ew hours. 

### If the leavGs are complQtety yollow, fomperarure and**ventilatiQl\'llu$~bG** adjustod in a mannerto dl)' the tobacco as fast as possible without scalding. Once the leaf is dried (314 dry), you should follow ntlrlflal procgduros for curmg. Sinco PREpl'ld treated leaves curefastor. Ireated and untroated leaves should not be cured togother in tho ;;mebarn. 

# 75**-.~-~~-~~~~~**

# LIMITED WARRANTY AND DISCLAIMER Tho manufacturerwarrants fa) thaI this product conforms to the chemical doscription on tho label; (b) thaI this product is reasonably 

### fit lor tho purposes sot forth In the directions lor Use when 

### it is used in accordanC4 with such directions; and (c) that tho dirOC1lons. werning and other statements on this label am based upon responsible experts' ovaluation 01 roasonablo losts 01 elfectivonoss. of toxicity to laboratory animals and to plants, and 01 rlllsiduos on food crops and upon reports oflleld experience. Tests have not boon 

### made on all varieties or in all states orunderall conditions. lHE MANUFACTURER NEITHER MAKES NOR INTENDS. NOR DOES IT AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE, ANY OTHER WARRANTIES. EXPRESS OR IMPLIED, AND IT 

### EXPRESSLY EXCLUDes AND DISCLAIMS All IMPLIED WARRANTIES OF MERCHANT·ABllITYOR FITNESS FOR A PARTICULAR PURPOSE. THIS WARRANTY DOES NOT EXTEND TO, AND THE BUYER SHALL BE SOLELY RESPONSIBLE FOR. ANY AND ALL LOSS OR DAMAGE WHICH RESULTS FROM THE USE OF THIS PRODUCT IN ANY MANNER WHICH IS INCONSISTENTWITH THE LABEL DIRECTIONS, WARNINGS 

### ORCAUTIONS. BUYER'S EXCLUSIVE REMEDY AND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY FOR ANY AND ALL CLAIMS, LOSSES, DAMAGES, OR INJURIES RESULTING FROM THE USE OR HANDLING OFl}USPRODUCT, WHETHER OR NOTBASED IN CONTRACT. NEGLIGENCE, STRICT LIABILITY IN TORT OR OTHERWISE SHALL BE LIMITED, ATTHE MANUFACTURER'S OProN. TO REPLACEMENTOF, 

### OR lliE REPAYMENT

### OF THE PURCHASE PRICE FOR, lHE QUANTIlY OF PRODUCT

### WITH RESPECTTO WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHALL MANUFACTURER OR SELLER BE LIABLE FOR SPECIAL INDIRECTOR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE 

### OR HANDLING OFTHIS PRODUCT, WHEN USE OR HANDUNG 

### IS NOT IN ACCORDANCE 

### WITH LABEL DlRECTlONS

.

... NOTICE TO BUYER

### ~urchaso 01 this product doos not contar any rights undQr patonls governing this produc1 or tho use thoroot in countries outsido 01 tho United StatQs

.



# •

lDEFand Gu!hion oro rGgistQred tradomarks 01 BayerAG, Germany. 2Dropp and Gil'lStarare rogistored trademarks and Ultra is a Iradomark 01 AgrEvo. 3Harvado is a registered tradomark 01 Uniroyal Company. "Malathion is a trademark 01 American Cyanamid Company.

Rh6no·PoulofIC Ag Company P.O. Box t2014, 2T.W. Aklxandor Drivo Rosoarch Trianglo Park. NoohCarolina 27709 PREP is tho trademark oj Rhono·Poulenc. FOLEX is a registerod trademark 01 Rh6ne·Poulenc. 

# .. . • ••



# •• •

• 

## • •••••• 

## •••• • 

## ••

•••

• • 

## •• •• •

•••• 

## ••• 

# • PREpno brand Ethephon tor Cotton and Tobacco (PENDING) Subm!lIed tlt6196, Resubmitted t131J97, Resubmitted 

# 8/.l!97.



# 76

.......**~** ...**~.--------------** 

## •

## ••••• • 

## •• 

## • • 

## •

# ••••• • •

•• '"

# ..

• • 

## •••••

## ---

- 

## --------_._-_._

..

# _._------------

RHONE-POULENC 11«", 3D 1 C;StS'l';Y)

## =~.- 

# .**'3~""-_"'.**E::'

## ""~~.~'**""""-~~""'~;~'--~~-~3"~**



# •



# • RHONE·POULENC AG COMPANY



### EPA Correspondence No. GSP/eth/o53 August 14. 1997

U.S. 

### EnvironmelltaJ Protection Agency 

### Office ofPesticide Programs Document Processing Desk (H7504C) Room 266A, Crystal Mall 2 

## 1921 Jefferson 

## Davis Highway Arlington, VA 22202 

### A(tn: Ms. Cynthia Giles Parker (PM No. 22), 

# 1 RE: EPA Reg NO.264-418 REP1M 

### brand Elhcphon for Cotton and Tohacco: Label revisions in respomc to 

### yourcomspondcm:e of Angost 

## I. 1997.

Dear Ms. Giles

- Parker,

I 

### am submitting five copies ofa draft label with the correction$ which YOII requested in your Angllst I, 1997 correspondence. 

# rim\'c 

## highlighted lilL' 

### changes Oil 

### one ofthese labels to [,lCilitate your review. Please note, Rhone Poulcnc would very llluth aJlpreciate a quickreviewofthis labeJ Oll your pan. Productioo for PREpTf'.1 begins in November for (he 1998 season. We wnuld like to be able to 

### have both EPA and C;liiromia approval belore then so fhar 

### we are able to Ilrodllce a)J product for the 1998**se;l.~on** 

### with the Sllme 

### label. All ofthe COlTelll 

### changes which have been made on this label are the same ;1$ 

### challges already approved 

## by rhe 

### Agency in Jilly whcn the PREP@/ethephon RED label changes were approved.

'fhefollowing ch:mgcs have been luade:

Hazards to Ihnualls Sectioll: Replaced text widl recommellded wording.

Statement ofPractical Trc<ltmcnt Section: Clwnged title to 

### '"FIRSTAID" Deleted "IfInhaled" Statement IfOll Skill: addcd: "Get medical :trtcntion," IfSwallo\','ed: Added "orPoison Control Ccnter",

Note t\) 

### Physician Section: Moved this section (rom 

### precautiollary SW'£Clllell{S 

### to FIRST /\11) 

### sCCI"ion 

## ••• • ••



## •••

• • •••••• 

### •

## •• • 

## • ••



## •• 

## • • 

## • •• 

## •• •



## •••• ••• • 

## ••

••**.~~~.**



### •

### ••••• 

### • 

## •• • • 

## •••••• 

### • •



## •• ••••• 

# • • •••••

Rj 80x**!2()1~** JTW A', i:.KAnOEfl**0n.v'~ i\E::;Lfl.I1C1111w.r,~t;::**  PAlii( tI C 

### n !ff.j_j{:,14 IIIHl;1;A:;"h,'Y')') 

### Excellence in 

### PerformanCe

'1IfHll>IAnOIJAl lHrx Wil/dFIl ·r):!}}7n,N

..!;:;';[FUJLI-(**M'(~** q II' 

### Pnde In

### Achlevemen! IUffRNt.TiCliAL[)ISffl.8lJnUN SUNI(;f-;; 1n LX hl;15;LH 1)')<_,7;-, "',(**8H"r,L~_:~"** M'(; ,,;5 

# 77

# •



# • Added: "Treat symptomatically. Consideration should be given to

## rhe possibility that Over

### exposure to materials otherthan this product may have: occurred. No 

## specific antidote is available. Probable mucosal damage may contraindicate the use ofgastric IlIvagc,"This sL.1tementcomplies with your input and was recommended 

## by ourcorporate physici;m as appropriate for

## all ethcphon labels. Deleted: Entire prior statement.



## PPE Section: Modified glove statement to meet current requirements.
Directions for Use section: Moved first paragraph from Agricultural Use Requirements box to text above box.
Use Limitations section: Modifed 2.0 Ib alIA statement as suggested

.

Ifyou 

## have Itny questions concerning this matter, J

## can be reached at 

## 919-549-2687.

Gail Powell.

## Ph.D. Registration M,magcr



# .. . • 

## ••

•• 

## •

• • 

## • •••••• 

## ••• • 

## • ••



## •• 

## • • • 

## •• •• •



## •••• ••• 

## • 

## • •

••


# 78 •••••• • 

## •• • • •••••• 

## • •



## •• ••••• 

## • • •••••

# • UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D,C. 20460



## Gail Powell**Rhone~Poulenc** 

### Ag Company P.O. Box 12014 

## Research Triangle Park, NC.27709
Dear Ms. Powell: OffiCE OF PREVENTION, PESTICIOES ANO TOXIC SUBSTANCES



## Subject: PREP'm 

## Brand Ethephon for Cocton and Tobacco EPA Registration Number 264-418 

## Your amendment application submission dated January 

## 29, 1997
The labeling referred to above, submitted in connection with 

### registration under the Federal Insecticide, Fungicide, and Rodenticide Act., as amended, is unacceptable. Please make the 

## following labeling changes;
1. Update the Hazards to HUmans section so it 

### reads as 

## follows: Corrosive. Causes irreversible eye damage and skin burns. Harmful 

## if swallowed or absorbed through the skin. Do not get in eyes or on skin or on clothing.
2. Delete the NOTE TO PHYSICIAN statement and add the**~** 

### following statement: Probable mucosal damage may contraindicate the use of gastric lavage.
3. In the Statement of Practical Treatment Section, you may delete the IF INHALED; section since this product is in Toxicity Category IV for inhalation toxicity.
4. In the same section as mentioned above, in the IF ON SKIN: statement, you must add the following statement: Get medical attention.
5. Move "Do not apply this product in a way
....agency responsible for pesticide regulations" out of the Agricultural**Use+Requirements~section** 

### to immediately below the heading "It is a violation of Federal

....with its labeling."



# 79

# •



# • 6. Modify the Use Limitation 50 it 

## is clear that the maximum 

## that can be applied to cotton is 2.0 lb. of ethephon as an active ingredient per acre from all sources of ethephon not just this product. 

## Please note that we are aware that the above changes were made on your label at the time of reregistration (label stamped 7/17/97)

. Sincerely yours, 

# hi Cynthia Gl{es-parker Product Manger (22) Fungicide Herbicide Branch Registration Division (H7S0SC)



# 80

# •

• PH ..., "')**~.~** EPA COMPANY NUl10ER 

# .2-':_(;, 'I

# ~

# g/

EPA REGlS'l'lU\'l'IOH IlUl1Blm 

### STATUS (For Amendment:s)

"ME-TOOH eX'i'ED PRODUCT 5'1'ATUS



### PHA'I' RECORD**CnEr~'rED** 

### Active 

# t/ Cancelled

__ _ Hot in REFS


### Active**Canc~lled** 

### Hot in HEFS



# 81

## // APPLICATION FOR. AMmIDMENT

WITH DATA 

### NO PAT1\.
INIT DATE 

### INIT DATE FEU FBU 

# .:h**d.~;2** -5--

# 5'?

PH 

# I,;:!..,:2- SIG (DATA) 

### PM



# ------ 

# •

•

82

### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460



## GAIL POWELL RHONE-POULENC AG COMPANY 

## P.O. BOX 12014 02/05/97

RESEARCH TRIANGLE PARK NC 27709



## PRODUCT NAME: PREP BRAND ETHEPHON FOR COTTON AND TOBACCO COMPANY NAME: RHONE-pOULENC AG COMPANY OPP IDENTIFICATION NUMBER: 242759 EPA REGISTRATION NUMBER: 264-418**~** 

## EPA RECEIPT DATE: 02/04/97



# • SUBJECT: RECEIPT OF AMENDMENT
DEAR REGISTRANT:
The Office of Pesticide Programs has received your application for an amendment and 

## it has passed an administrative screen for completeness. During the initial screen we determined that the application qualifies for fast track review. The package will now be forwarded to the Product Manager for review to determine its acceptability.


### If you 

### have any 

## questions I 

### please contact C. Giles-parker, Product Manager 22/ at (703}-305-5540
.



## Sincerely1



### Front End Processing staff Information services Branch Program Management and support Division

RecyclediRecyclablo J>Mlfd wIIh SoyiCal\olDlllkon**~** fl><Il**C<I~lll"',"I"'I~~\lH'**

# '" 

# .•.

, 

# &EPA • United lhfitlU 

## Environmental Protection Agency W4,hlngtOJl, pc 20400 

## I-- 

## Registration**~** 

## Amendment 

## '- Other 

# 242759

1. CompanylPrcduet Numb.r

4.'

Is, Narno and Ad4r&1W of II IlncluOI1 ZiP Cedel 

## Rhone-Poulenc Ag company P. O. Box 12014**Re'se'f"ep.~Trian91e** 

## Pack, NC 27709 

# I -,

# Ch-;;;;if(his jp tI n"wnddtoil'S 

## for 

# ,"
2. EPA Prod\lct M!.nilGf/t 

# c" PM' 

### 22 

# "
3. Proposed Cfl1uifKllltion 

# o NOM 

# 0**Ro~trietlXl**

6. Expedited Reviaw. In accordance with FIFRA Section 3(cj!31**~bHil,** 

### my ptoduct is similar or identical In composition and labeling 

### to, EPA Reg. No.

___ . ___________ .. Product Name



## ," II

Explanation: u.o additIonal 

### peg,*1 if fi<jclltisary. 

### (For fl"""on J

### and Soction

### IL) 

### -Changes in "Directions for: Use and**E.~~~ction-,~~for** 

### Tank Mixtures"


# --**"ru----------~~~--~**

2. 

### TV.,. of Ccmtrurwr

# :::~' Glen, PSP'H Other ISpeeifyl.

___ ,,'

___ _ If**Myu~** No. pM UNI PackugiflQ Wilt, eontaIner



### 3. ,.,N,," :4

.....,,' "". 

# lliJ ""'" 

# 0**Co",~~'** 1, 

### 2.5, 5.0, 110 

# aa\/bulJ->:-!

# :;::'t:E: 30, prOOtlc:t

# ~.- ..

# -M--'"-"'--'-'"-Vl--N-'.-h-L-.-b~--i.--A-ffi- ••

-..

--'.--P-'.,--'_"

___..

# ~ ...

# ~ i 

### Wrapper g 1!)OO**to,~** 

### ins 

### Label 

# 11. Cont&(;t Poll'lt


### Gail.**Powe~l** 

## , elV
Il&b. 

# I""'.

. Reglstcatlon Certification 

## Manager

# ~

# ::::"



# .. I cartilv Ihllt Ihl! lltntl!montll I h9VS mooe on

### tN.form a!'ld $3 IIttflchffitml$**th~falo** fire tru., &tcursto and complelll, I tld:nowlodlJj!l thai any knowIngly fDiu <n ml;JeliKJing Iltlliomenr mi!ly bit puNch:&tll. byfrttb I:;If imprilOI'\mOni or hoth UM" applle,blo law, 

# I,,} (Stamped)

# 12.s_""'~'",,~/a~/14~,J]~rJ~·__

# _+3~'''''~'==~~----~I~ r--**~IjY~~t** ·.flO! 

## Registcation Manager

# ~ 4. TyplifJ NIlll'It' $,ollte


## Gait Powell
EPA Fo<m 867

..' (RoY

....., 

# - .

# --_._-
•

PAPERWORK REDUCTION ACT NOTICE and INSTRUCTIONS


### PAPERWORK REOUCTION ACT NQTtCE; PuI>Hc reporting

### trurd," lor this

### tlullcction afinformation is Mtlmated

### to $ljIlTGIi1' 0,85 houtjHlf ((!$peMl'I, >'¢!uillng 11m3 fOf re\4uwlng inilitroctiom;, searohing &)(l$\/ng data lI00fl!Il$, gntharlng.oo mnintaln/nu liw d.\lw Mooed, and**S(l~tlng** ond rtvlaWihO tho Co!/(I!Hlon of information, S;ma Gomfth:lh\ltti!g&ttHng tho b<lrden utlmate or anycInar aIIpect of thi, colHu:tlon ofIn/ormation, including suOaa3\ions '(If riitdudnq thh' uurd<i"!1, to Chief. I,.,"-'rmati",., PelleyIiHIru;h, {213Gl. U,S, EnltlrOl'olThllntlll ProU.ction AO<lnev, 401 M Stroot, SW. W4$rnngtor:, D<': 20400,
INSTBUCTlONS: Thl$ (orm if! to bIJ us!'!? forcll applieiltior;$ {(If MW tOwstrlitlon, and 1.1$0 flltoQilmalion, alT1endlT\l:lllt. tl)wbinlUion, to II'pplilllltiolHl for n(HifictItJof'lll, tinm printGd Itlbeli"'\J, Iflrl.)(Jiutnltjon, IiIlt. ttl**ord~f** 10

### proceu an 3PpiicaUon fat II twlW rdglS"trotion fwhmluod on troll form, the lollowin:1 

### mal1Hlm must I'lCeCmpIlnV t!tll Gppliem).:m: 1. Certlfletttioll witl! R.upetrl 10 Cl1i11titm "I 011\1> (EPA rerm $570-29). lit not tl"l<empt'l'd by 40 em 152.31 (bj (<Ill; :L Confodeotilll Slatlllllflnt 01 Fctnwia itPA Form 8570>4); 3. FOlmul/ltOf'$ f>i!ffl\ptioh Statum

..n! ICftA Form SS70·2.71: 4. Flv!} eople% of dreft Ilibellng; 5. Thli!l0 eopl<w of#fiV dalll l!ubmhted;
o. AuthMilllJion ltottCf whlUfI IltpKtr!0l;;; 7. Mlltrico$ willlr!> epplleOOIIl.**Submk~l6h** of lllu¢!{ng "**lhbt~Jjno** $hCtuld**fj,~t** b$**~,-,bn-Jufd** in lllll ferm of u(!lft Icl!eli> wilh Ii!! eppticetiuJ)Q fer MW**rffDl~trl}tlWI.** Sl.ICh atllft 100/)1$ IlWVhI! in the form oll','11ud label [ext en 8,5 l( 11 Inch !"'):lSt fOf !1ubmiimico tlr lil trHH;kup Dr th0 Pl6potud Iwtl, Ifprepllted formO(:jQJp, it

### $tmuW Ia t;Ul'lStructt4 ill 11 ¥lOY as Wfzci/it6!e ll!GraiJ4 m en $,5 x 11 ;rwh fih. M'Kkup l!lbth:**!fi(:Jr~hel!iltiv** :IImaJ1er than $,5xli ltwrnHj shouldbe moumttd {ttl 8,5 y 11 ;nell PllPM 16r tubmiw&ion, Submi"don of 011111' OM,.

## sut)(l'~tt"il ill "WIi!:>Gn; of lhis oI'PDlid!l1!Ofl mutt

## b~ subrnittd If) e,;:cord

..m;e with PH Notice 86-5, 

# (It

ill..C1F!C INSTRUCTIONS;**Pi~il~11** n&! (he i<;ttrud.!6I'lli bted**b~bw** bilk"" compbt,l1[l tfuS epplic&tion, 

### Artl deteHnhw the tWit (If f$Qi$triltlMI tlGUon, til<km If! 81c'0k A, fOt wNch '10'-' Nil u,blnmmo this NPI'HC1!hol1, Vcr q,pth;ali!)l"w tublf'lftN in cor.f(tcti"n Witt; Naw**Rtgi1>lf~ti6f1** actiom;, S@c\klm I, 1H, lind IV must be (omph!!!!d Ly Ih", llpplJuiiM. For GpfJlitdWns 'll1,lbmithtt'l ill COHI1*,,;;un with umerdw INllglstrnti{H'llllctioM, re$\lbrnllldoM, rQJ!lic4'iofl$, 1l!U!;f,ttuatIOti:>, !Ht., Siiot;lif;IW I, If, Gnd IV 

### !Twn b& complalad by the "ppliGJlIlt. ill",;k A· Ch;;r,J,: tho ltflP,oprlil((I IK"!iQ'" for which you "m sutmHlillll tll)s fDlm,


### SECTION I

.**Tffi~** Motion mutt tit complt.g,;j. WI ll[miia,bl"" for ejj mQl$lttljion 1l.(;1lr.",,,. I. CompenyiProduu Numbu· IrH'llIrl yevr C"mt:Hlny NumDtt, ,f orm fHW be"l1 4#"'Yfl¢cl by EPA. Thb: number rrury fu:\la been 

### 1n,w"rwd to you 1l$

# '* t;"'tiC r00!H!4nt, 4 d'$lribuIM, 6t Wi' ik' !JffAbbthrr","t, II your PWd';.H:1 ill r"'ub-tcrud, in/ant the PrOO\H:t Numher. ::L EPA Ptodut:t I'th

....agll( 0 If known, W! j'(j iM n"nw ll1U PM number 01 !M- EPA Prooutt MEnllgM" J. Pr/}jlC4"!l(j' CllirowficMIm\. Spec'ly lhlt P(;:'PQ%W <;,j;%mfil:llliGn of til". plodue!. 4. P(od\Je1 N&IT'dI· Enterthe compl611$ fHlYlu-c.! Mr0& of thil! !HMtid" bllil wi!1 4'(;8$1 tift In{< l;JotL 

## nw rtam6**rffiJ~t** be- speeiflc 10 OAt prMU(lt only. DuphtlHwn of fllliT!<l'S i1; nN**pj:jffl~it~d** Mwn\:l pI¢d\Jch, cf tho ::-IIm!!**~mtlp@ny,** 0" not ;ndude- any br;;nd mUTH.! ot

### ¢OffI9&1fflitM dIl4ijm1th:ms, 5, N'Itm. $rid Add,_ 01 A!Ij1:1kMnt' Too mum!' IA lilt> firm IH per1!OIl and &ddrjJJ!@ dlOwn In yWt appltcatitm is Jlw pefilon &r firm til' whom Ihg f¢u'QHhlitm wi!! he inWlltt If yIN lifO lwtir,a in beh.clf of (lIH;;tt\l]I( PMty, y;-lti imillt lluOmit euth(lfiz<:!lIon from tlvlt l'iiVty tQ act 1&IhMft III r&{lill!lf61lM multN$, An uPPU;;/>l!l net (fH!id!n-g In tII\lI Vnii<'i-d StdQIl mUd f1i:lvt! an auth"r!n,t.! egen! 11lMJing jI; the UnitW' Stat

..; 

### to MtfIX th;nn in /iU**r~oi1Hrill;':1fl** matt<lf'#, Tho IHlmo nm! compliH6 nMi!lflQ aJdretll of w,wh Cil J>lj{!nt (tIti$t ifOotmlpenr this &pptlaMlon. tL**E:'1"adllad.fl~Vi%W:** FlfR-A section 3-lc)**~** (ej pfDv;-de* fOf <::'1;)00;1«1 rtNiew**~f** uppliC-lltitlM for reghmllliM, cr**em'H;dow~u;** to existing l,ttu\'tl1!Wfli,) tll"'t Me mrrulM Otkhm1lcml til Qtlwr**pti~t!tod$** pwduc:tll Jh!lt are CUrrlh'llly r&u,wler<'>d with the EPA. In erda, for your**~ei!thm** to lM elig!bla for, '_ fwpadjtlld fllvllilW, 'loti rtIti$t proVio", tiS with [ha EPA !\nO!Sfll<ilofl NUIY,vllr lInd proouH n&lie !lllho pfiXfuct you b&lil!v(!l!; lllmifu to Ot jdilnliecl to your product. Tnllt Plodllel mut! b

.. iIIirrHU or ;der;!ic:ci ill both f<lfm\llMkm Am! loo"led u\l4!l. 

### SECTION II • TN, !lH}lltio-ll tn\J!lt {HI emnplet.x! 

### Im.-.1l <1fpiio<1t)""g ;H.lomiUed 

### to 6ffHmd tM I1lIJi><tratiOrl 

### ohly of <I: 

### t:urrenuy f8W&tlltWj'ilc4U¢t lAm'lmimelHl, fe< II r<Hllubrnh:-§ion**j~** f:lltpl)f1,,:e It) -Uf> Agency lltl\or, flJr lWtllltiM'erm W the A\i$fWV. fot 1M ",ubmill'$lon of flM primedfnholinU, fer r"HlwMrillkll1 find for !lny other MII"n th<lt**p"'t"''''~** !tl ;'j**lw~<;lfii:'** g?A·rQ\1h!MOO pf(,.j',ct. This**g~ctlen**

# "t i!i2! 12

### h2 Ulied fur JiI 

### ""wbppIIt

..t],:m lor r"oi,llal)on_ I.**SUD~ct** of iliubm!lflIloo • eM!)k the !!ppr.ogblll block {1m:! pro'lidl) ttl<> AQOnuy !uner datlt 'f &pproplj!llft, P.ovil1<) u brief oxpianothm o-f

## tm. p\.lrpo&cls) fur the ;!;ubmission. ,-"ch IH' "theMdJti&n ;)! Ii ",!te, peit or !:fop lfpeclfyr;**~ijmllnd** too**C{)nfid~nti~** $11'iIemcnt of FOm\ulll**bV,.,~; ~t<'l(~!l-tr;jrJan** **~ubrni!ltlotl~; ~gentfcl**  f.mltl**mvi~lorr** {)f <is!! dUeniQrm.H Attm:h a sttpnrtlte PftlJl' [I eddit!ol'l1H fpMe il ",ednd. 

### SECTION III {Paokllgino amJ Contairvlf Infolmmlt;nJ

. ihill Section mtmt bo eorrl'plllt¢d f<)f att tlppllc81kmn submiuos(f in connection With fI!IW rtuistrlltiofi or ucplfcahlu iml6m!mijl'lt1l. I < Type 01 Packaging· Chock the IIPpmprillt<! block if yllur pr;;;d!H:t w1l! Ile pili:kaj;ld in the IndicotmJ ptwkawnu typos. Indicats tntl gilt! oftlw: Individual pdckal$" and number per r.;;lml (;on\clmlf, 2, Typll! of Rfltllil Cor;'tllintf· IndioJlle typo of eCfltrnnllf in which prvdu¢\ will bo O1mk4tod. 3. Locatinn 01 Not CcnllilnW "**hldieat~** tha !<Icalh'.m oflila r:l)t tl(lnlimta information {(lr ¥"ur prodUtlL 4.**Si:l:fI{~1** (II ltatllU Cootlillner· Splloitythll net contuolS 01 lill retail contlliMf!ll Il1tylltlfproduct. S. L()oedon- of !he DIrection. ·lndicUle tho locanOIl of thu use d,r$Cliof1$ 101 'lour product. 6. Mannef In wh,ch lab.1 k aflb;od to product Indlcllted the lnijtnw proo\u:t lilbel**h~** 111l3Chod to rlltml (;onlalnlllr" 

### SECTION IV (Contact POInt)· TN. Section mUllt i.l0l c¢ll1pj!!t<ld fa afl appli(13tior:lIlor Atwetratinn &eli(m,-, ).0., new prfX!u.:tt**r~lllr$llon,** rll$obmill$jon.**~1"l>1)·too,·** re-rog!st/o\ion, lite. 1-5. SlIlf·(lltplanatQry. G. EPA V,,, Ody.0

....... 

# j/**-----~------** 

# j,:!**-~---** Un!Ud StD'U,$ 

## Environmental Protection Agency WaehillQto!'l, OC 20460

## for 

# I-:-:- Reglstratlon 

# p{. Amendment
L- 

## Other "Section I ( 

# ''''''".

11.< Number ? 

### i4 .,

# H~""'l 'P 

# 13. Pfcpcaod Oe

.. irtOotlon 

# ONen. 

# D RII.trietlld j',,,-, Q, d. .' f. 

# .',

:5, Nnnw end Add,

... of App5Clfnt (lncluda ZIP CQdo} 

### 6. Expedited Review. In accordance with FIFRA Section 3(cH3) 

# ::w, mv product)s similar

# gtidentical in 

### composition and labeling


### EPA Rog.**No.~~~~~~~~~~~~~_** 

### Product Name



## ," II 

# I i

Amendment

- Explain beloW. 

# 0 Rnlll prinred labalal" r.'p<m1l"6 to 

# D AglmcyIIIItG! dated 

### -------"'0,----'

# I Rewbmluionin rcspcmo to AIlO'rnlY louo, dllllld**~------** 

# n**~Me Tco~**  Application_ /**;:~,** 

# o**N~lieation·** Explain b&lcw. 

## U Othor· E:.!piain balow. 

### -:i
ExplanatIon: Use itddilloMi pIIO"hl) if n/tcafll1:Cry, (For $aellon I and SoctiO'n ILl



### ')**I~'**

# .~------------------_4

# ~'U~iC~~_:~:_'______

# ·_·~··______

# ~~~'~7:~;~.~.p_'~_'~'7~_ng ____

# --1"~.~~' If "Y••**~** No. plH'**~ylll"~** No.por**~** Pap.r Unit P&Ck'glWJ wgt. conlalner wgt conlaiM'r 

### f/' OtMr ISpl>CifVI

______ _
3. 

# ,,!N,,' 14.

# $I",.,

..., g] I.B1af 

# 0 Containar 

# r'-'M_'_'"_'_'_'",-W_"_'_h_lob

_ "_'_'_A_"_'_"'_'_'_P_''''_"_'_'_

....

# ~_ oh



### CertificatIon 

# [g] Olher


## ·IV 

## 10" Pl;-H5tir- Vkv,,:,,·,'i.- 

### _?'ii"f' ,.-, CDM.nne(DOn(,(id( '.eipe'

### I.~

# ... I certlfy Ih6t too otfltomt-nls I have mode on this iorm-And ail stt&ehmllnts thbreto are tria, .ec:urate Mod eompIetll. 

## I.i· I

# ~-::.2!'~"~'~""~W~''''7''~'''~'~·~'''!!::k~''_W_''''_Y_'_''_'_'_'_'_~_·._'- 

# __**'_'_",--:-:::-"~' ~**  

# __ Y_b_'_"'_"'

_____ bY_r"'

__ 

# M_""'

__**'_~_"""** 

# __ "'_'_'

__**~i.**b..... 

## 4Stampedl 

## t hoth undO'r lew.

# ~2~'S~i'M~~~·D~<~~~_D~f~'~~i~(~I~·/ ________

# -4~3'~To_·~_'~D~f:"~":7~'I:,"~G':"':'0::________

# ~i~ 4. Typcd Nona 5. Oot.



### EPA 

### Fomo 8670-', 

# ........." • Copy

### PAPERWORK REDUCTION ACT NOTICE and INSTRUCTIONS


### PAPERWORK REQUCTION ACT NOTICE: F'lJhlili r6portlna hurdcl1lor this tallctnJeri'

# ofinformationis Ktlm6t&d 10

### Werage 0.85 hour por renponec. '''<Iudtog t!ow fO( ''''''I1Winll inlUrul.llioiW, 1lI0atchlng: omllhno dllta Boureutl, oathering lind maintaining t!w date needed, 4I'\d t!Off'IPItting and revil'lw!ng tho ool!lIOfwn 01 inllHffitl\lon. Send: eO/fllTllll\I$ MjjMdinO 1Mburd

..n utima\o Of any otmr a'pect of this oel/cationoflnfbtIDSllon, including turu;Mt.t{)m; lor radudf\\llhiJJ burdon, to Chiol, Information Po,ljoy Sr!lnllh, 1213&1. U,S. EnvirOnMental Protection AOfInoy, 

## 401 tiiI Sfillet, SW, WlI'$hll\{lton, DC 1046(L INSTRUCTIONS; TN:t hrm is \0 be U§!)d for alillppliMtioM lor r'!bW (oQlslratJon, cnd U$O rer0olSl,Mion, OO'HIndment, r.submistion, to lIpJ)#eaUolW lor I1(lrifieouolW. final printod IIIb&!lfll). f(lfepilllflUlon, etc. In ardor Itl process on f4lpllelltlon 

### for a new 

### toa!,lrouon #I.IbmItted O'n thl" form, Ita following I'fWIlarfai niUst ae::omj:)MY Ihe appliominn: 

### t. CortillGJil$)n with

### Rnpoct to Cl\lJllon 01 00111 IEPA Form &570·2SI. III nOlllXllmptlld by 40 CFR 152,81 /h) t41l: 2, Confld6fldtil SWtom4nt of Formu!a IEPA Form 8570·4); 3. fnrmuliltor', EXMI'Iption SUilcmenljEPA form 8570-27): 4. five copiell 01 draft labofing: 

## s. Thrall oopio. 01 MY dllte ,ubmilled; 

## a. AUll\¢riutlon leiter wtWIl IIpplwilblll; 7. MalricDS where Dflpfkable. ,S",,,,,.,,hm 01 t..haling

. l..ablillng 1Iih(HJ!d lirsl hi> tubrnined in lhu form 01 ({rftft !lfblll, wllh lIIIl $ppliellllioll$ lor I\IIW registrlltion. Such droft looo!s typed label te)(t 

### on 3.5 x 11 inch paper lor mJbmh,:;lol1 or II mockUp of tM propoSlld lab&!. If (neplJred for mockup. itahould be

### ;:::~:~:~:~iiil way Ifll< 10 fl/llllillilil stoma. in lin 8.5x It iw.:h file. Mcekup labels sigt'lHieantty sm&l!llr IhM 8.5X 11 Inch" should be1'rn:xmhx{ on 8,5

fM $ubmlstOOn. of Olte • Oalil IllJbmiltad ill !;UPport 01

## rl~s epplielllion musl be lluumittlld in ae::ordon::o wllh PR Nolioe 80·5. 

# e**l~fl;£lE!l:,lli~:!l.!1i;]JIQ!il!;** pjll:l$1! r<!(lt! tha inStn)¢lloll$li${ed I.HlIOW bdore ccmplOlinglhis appUcarion. First delermine tfa

## twa of ttlaiglfeUOn A. lor wive!'! you Ute ,ubmltling Ihill application. For applieationll submitted in oonnection wIth New Registration ootiO"', Se(;tiam !V muSI blJ eomp!elll'd by 111$ applk:Mt. For I.lPPlic(l\1oml §ubmit\ed in conMotJon with GITlllnd@dreregislral!,,"OelioM',f$,ubmtcs{on8.

### 1~"ilj""lQ"" rerIlQi$trlllinn" ate.•

### S~tllionll!, U, and IV moll! bo ::OInplaled bV rhllllpplielUlt. A • Check tJIC nppr"pri<l\!:1 aOlion lor whh:;h you @ro $Ubmlttino thi!J 10flTl,

## 1~!£j;;:rJQ!il' This =<lllllon muU bo ::ompI"IfU!, 4$ apph'c

..tM. for nil rl,lQis:UiIouon

## ~tl<Jm:, 1. CQfftfHmyiPl';,ducl Numb.r· IMen your Compllny Numb!!r, If orno hlilt bean allwiuood by ePA. Thl, numb!!r may havo baen 1II,lIigMdlo Y¢1J allJ bUlo rllghmant, III disrribulor. or

# m. an**esrl!b!i5hm~'"t.** II your product!9 regilllerod, Ill1Iort Ih. Proouct Numbar. 2, EPA PtoduelMIIIMGM**~** 1/ k-noWfi, lill in lhti 'n/llua lind I'M numiHlt 01 the ErA f'roduat Manager. 3. Propoud Cta!!ifIcatlon**~** Spocify 11\"**propO~$d** ellluifiellUon nf lhit prOOuct. 4. Pfo/fucl N.rne· Enter tM ecmplata proou(ll miMe of this pulicide I1S It wj!lllppur on 1M IlIbM. Tfa nama roo$1 be' spedflc t(llfill producl only. OupIkatlo:n of Mf11<1a Is 001 PIUmitled llmong prodtwlli of Ih" Salmi company. 00 nol irn:dudtl any brand MOW {)f eomfHmv**Umfd~thms.** 5. Namo end Addr

... el Apr»ieant • The name of 1M firm or pMlIon 1.Ind e<!dfuS IIlwwn In your**IIf>P~Cillh:,"** 

### hlltapertlon ot fum to wru:.mlh. U1Wfi'uauan win bo h'lIuDd. If you oro Il<lting in bahnll ofI'Hl¢ll\or porI\', you must lIubmllllulMrilatlon**Ir~** IhlJtporty 

### U, oct f'Or 1hllffj in reghltrallon tnlilww. An**IIpplil:~flt** notl11llldl!'li} in Iha Unilud Slutes must hllve lin lIulhori:uid lIQont r01l!ding In the Unlled Siallll' to &Ot for them in llR regi51ra\ion mallors, Tho name and ct.l'fl1!l!.le Il'm!lIng edQ"rll$!l of$\.l::h an n{ltfll mulll aacomp"nr till!> epplle1.ltitm, 6.**~dl~d** ReliWw· F!FRA s!l:IlUon 3 lel3 l6i prOvidl!lI for iJxpedilH rovi"w ofappljeutiof1# for rcgiS(flllion. Or trmall1,fnuln18 to**'~'~"'!"~''':"** that IV. lIlmifor OIldul'lt$(:IIIIIO orher pltMicWe productathatore currently t'1Jgistcf!td 

### with the EPA, In order for ytlUt llfiptloeoon te c.tpmhtoo reviow. you mullt pro0de us with IIHi' EPA RIlj)islrMion Number and product nil!'l1l1 of Ifwj- produet you

## ileuM Is: .imilar

# ""w,""", 'fOllr product. The product mullt b,simifM or iden1ical1n holh lomwlation <100 lalal&d US$$.

1, Subject of lI;ubmiJIalon • Chllck Ihe upp:J¢o!)le bfoek and provide: tho Aoency IMlerdOlO If 4pproprlate. Provld. 16 bria' oxph.nation of Ih1ll pU!"fW#oitl for the: lmhmiulon, suchas "lila addition 01 II tiro, pesl or orop l$poeifyl-; wwmtnd 1M- Conf(domii>l Slolllnwnt 01 Formula by

...·: wrerogi$trllliion wbmilllliol'l"; "gtMrnlInbel revi5ion of U5e dir:eetlon$," Allneh" Separale;

# p*il oddiUonili 'pace !$ MOOed.

## ~~!!i~~~ jPaCKoglnq lind Conllil(lOf !ntormarkmJ- TfU$ Seotion musl be ::i>mpIoted for allapplieatlont; =ulmilllod 

### in eonMctlon with now or epplieabltl amendmenl$', TYIUt cot Paellil;;";

- Chock the approprillie tJloek If y(Rlr pro>dw::1 wi!1 bo pa::kagedin the indiealed paekliQing typOt. lndieala thll $l'zo of Ino iOOhridual plfckol. and numlmr perr(lloll cont41Mr. Typo ofRetail CbntJm.t· IndlclIl. typo 01 containtH In whloh producl wiN bl! mmeleU, lnclllhm of Nel'**~nlents** - !ndhlate 1M localion of rlla nul eonl

..nUl in/nrrmltion for yetlr product. SiNic}.offlotllil C0fI1l1in«' Specify Ihe flol contel'lls of WI relail oonloinelll fot your producl. LCHlellon of USi!**O~cliotlll** -Inc!!::ol(l IhlJ location 01 Ihlt use dirllclloml lor ynur produot. MaM4»' In which lobo! is**affi~.d** 10 produet· Indlel'l(ed 1M melhod produel111blll j$ attached 10 r$lail ::onl.ciMr•

.**S~I·.XplamlIMy.**



### EPA U,e Only.

# •

• Date 

### of IlOOl.ic:aUa'l

_____ _

### ~ of 

### Product PRF;ptm n;;Qod l':;t.benhQQ for; CQt too ann Tobaccn



### P. O. 110% 

### J.2014
Reseilcch Tdang**~~** 

### Park! NC 27709



### 1. 11115 

### application is**~** 

### by 

### all data subaitted 

### or cited in the IR)lieation. In 

### addition, if 

### ciu-all op1:.1QM are indieaud. this 

### applieat.icn 

### is BUCp:)r'ud by 

### all 

### data in the 

### Jqencyl

### S tilM thAt. 

### concern the 

### prcpertles 

### or ettecu of this 

### croduct. or of 

# anv other cro:hlct:. that 

### is idenucal or sUDltantially similar. and th.I.t 

### is OM of 

### the CypetI 

### of data thn wculd be 

### required 'to 

### be 

### sutmitted 

### if this applicat.1cn ICUQht 

### the 

### initial reqistration 

### of a p:oduc:e 

### of ident.ieal or similar oq.-it1m and 

### intended. IJSH 

### under the 

### data 

### requinment:.!1 in 

### effeet; a\ 

### the 

### date of apptCNal 

### of 

### tfUs awlic.ation.
2.. 

### r certify t..'wt, 

### for each 

### Study 

### cited 

## in**~** 

### of this 

### application tor registration ehat 

### is an exclusive 

## us. at:Udy, I have obtained the writun**~tmiUlon** 

### of

# t.'" Or'xqinal data 

### .ut:mltter to elta that 

### studv_ 

## 3. I certify th.It. 

### for eaet'l study cited in 

## supcon of this 

### colication for reQ1Suation t.hat. 

### is not 

### an exclusive use uudy: 

# - I have obtained**tl'!~** 

### written pemiSSicn of the 

### original. data su.t:mitUJ:.n 

### to 

### cite th.at so.x1y: 

## S. 

## t9 I 

### t have nexified in writ1nJ 

### the ctI'IIpanies who 

### have 

### lI'1.Itnitud 

### r1au I haVe 

### cited to sutII::IOn: t."tis 

### a1)p.lieat.ion and 

### h&v. 

### offered to: 

### (a) p.y**COI~~t.ion** 

### fO\" "'-" data 

### in.=- with """"1",, 3(0)(1)(0) antll(c)(2)(0) 

## ¢ the _ra1 

### I_Icicle. FIIIlqidcle and 

### _icicle l\ct, ..., 

### (b) CUo_ negotia.tia"l.li to 

### detemino \ll\ich data 

## an SUbject 

### to the (£4t6IW,&t.ion**~** 

### requit•• nt. of 

## tIm ard the eount. 

### an:I tams of cu1C*ns&tion duef 

### if 

### &rtf. 'l'M**~es** 

### I have 

### not.ified 

## an: (Oeck 

### awl {x.l All**~i"** 

### listed a'l 

### the 

### Pesticic1e Dau Sut:Ditters tJ.at for 

### .t.ll acti,,,. 

### ir¥1Adient.S 

### contained in my prodUce 

### (Cit......u mHbOd 

### or cit

..... U option wder Selecti" Met.hex!.)-. (Also sign 'the 

### General 

## otter to Pay SUt.B'ftent 

### c.lcw.) 

# r J 'IIlOM**~i**

### .. _ """" 

## _<ted the 

## otutliea which 

### I have 

### cit.ed (S6lect.ive tllltthrxU

Date 

### 1I?'9/97



### General Offer to 

### Pay: t 

## huetJV offer 

### arJ!: aqree 

### to -pey Wi\MllUdon. to 

### Od\tIr 

### pat'1lCl'lS, 

## with nqarct 

### to the epc::a:oval of this 

### a;IIplieat.icn

.. to 

### U\e onent 

### roquired by FImA NC. 3(e)(1)(D) 

### an:!**3Jc)(2)(~.** 

### Siana=-

# /M/~d( TiUe

(A!>r,l 1985) Gai.J Povel 1 

### RegIstration Manager



# 88

# •

• RH6NE·POUlENCASCOMPANY



### EPA Correspondence No, GSP/elh!040 January 

### 31.1997

U.S. Environmental Protection Agency Office ofPesticide Programs Document Processing Desk (H7504C) Room 26M. CryStal Mall 

### 2 1921 

## Jefferson Davis Highway Arlington, VA 22202 

## Attn: Ms. Cynthia Ciites Parker (Pt-.-1 No. 22), 

# ...

# . '. • 

## •• • • •••••• 

### • •



## •• ••••• 

### • • ••••• 

## •• •• 

## • • •• • •••• 

# • •

•

## ••• • • • 

## ••

•

## ••• • 

# · 

# .. •• •



## •••• 

# ". 

# . • 

## •

••

RE: PrcpT.\f brand Elhephon 

### for Cotton and Tobacco (EPA Reg No,: 264-418); 

### Label Amendment



### DearMs.**Giles~P,'lIker,**



### Iam 

### sHbmilling five copics ofa revised PREpTM brand Ethephon for CottOil andTobncco 

### label. Please \Iote 

### this label 

## also contains revisions which \vere submitted to the Agency in January. 1996 itS 

### pan ofthe Ethephon reregistnnion process. TheJanuary 1996 

### revisions have not yet been approved. 1have highlightedthe new 

### proposed label revisions 

### on one copy ofthe submitted label.


### The following chimges hnve 

### been made:



## "Tank Mixtures with DcfoHants and Insecticides" 

## Seclion:

Added Dropp@ Ultrar.\I and Ginslar® to the list ofproducts.

"Directions for Use 

## Section":

COllon Tahk: "Spmy 

### Volume" column: 

### Changed title to 

### '"Minimum Spray Volumes",

Added footnote: "Fornest 

### perfonnance by ground or air applicarion, chouse eAluipment 

### and spray volumes thilt 

### will insure 

### unifonn coverage offoliage 

### ;lIld bolls"

'"GSOK**\;Sl~·:** 2 

### rw ALfXAJ;"<'iH i:ll"JL l<f;;rAI'lei iTHIN,(;t.f !'Nll( t-) r: ?/;'('1-;::14 (!:JJG)5{1l·;?Jfl) 

### Excellence In 

### Performance Pnde In

### AchJevemenr IlHfJmNI()flAt 1[1 ex hutAfiH1**,b~()TU** Ai r;,Yii'Ri',ACf;**A,,-~** ;-ui"' IlflfHHAl{(JNAL D;g,RIGuT\CN SHMCfS-**rL~** EX nUl-.l8fA**~9'Ynn-·Mb'i,i_PBAC"** Ai'\': '11:', 

# 89

# . '



# • • Deleted 

## upperlimitsfor all spray

## volumes. Changed spray volumes from 15 to 10 gallons/Acre for PREP'I'M, PREpTM +

## FOLEX® and preconditioner treatments.

"UseLimitations" Section:


## Added statement to address small grain intercropJling. This statement allows for 

## planting ofsmall b1fains priorto or immediately following harvest for soil erosion control 

## ifwheat is not harvested or grazed, The statement lIsed was modeled after a similar statement on the AgrEvo's Dropp®UltraTM label which is EPA approved. I have attached an article "Terminated-Wheat Cotron Best TexasDroughtOption" 

### from Cotton FanningMagazine. l1!is article explains rhe practiceofterminated 

## wheat-cotton production in Texas. In Texas, wheat is commonly plantedin cottOIl 

## fields prior to orimmediately following han'cstfor soil erosion control. This is " practice developed. andrecommended by 

## the USDA. The

## current label restriction would prevent [he use ofthis soil erosion COittrOJ practice 

## ill PREplM treated fields.

TobaccoTable: "Spray Volume" column: Changed title to

## "Minimum Spray 

## Volumes".
Deleted upper limit'> for aU 

## spray volumes.



## "Limited Warranty and Disclaimer" Section
Corrected typographical error 

## in last sentence ofwarranty 

## and disclaimer statement.
Added footnotes forDropp® 

## UltralM 

## ;md Ginslar®.

I 

## have included the following fonus: CenificaJion witli Respect to Citation ofDatannd Application for Pesticide (8570·1).


## Thank you for yonrhelp on this amendment. I<:an be 

## reached at 919-549-2687 if

## yon have any q1lcstions. 

# Si,ry'Y, 

# /i/JILL!

Gail Powell, Ph.D.



# 90

# PREp TM

# brand Ethephon FaA COTTON AND TOBACCO
For Commercial Use Or Agricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: Ethephon (2·Chloroethyl) phosphonic acid'

...................."

......"".""

....."

...""

.....55.4% INERT INGREDIENTS:

........................................................................................................................... 44.6% 

### aThis product contains 6 pounds elhephon per gallon. EPA Reg. 

### No. 264·418 

### EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN, 

# DANGER PELIGRO

5i usloo no ontiondo ta &Ilquela, busquo aalguion para quo so la exp!iquo a uslod en delano. (If you do nol understand tho laba!, find someone 10 explain illo you in detaiL) 

# e For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1·800·334·7577 

### For PRODUCT

# use. Information Call 1-800-334·9745**.:l,~t::';** Tho US8 of this product for a varioty of ptant growth rogutalion uses are protocted 

### by United 

### Siaies and loroign patents 

### including" 

### ".1 U.S. Patent 4.240.819, No liconso is granted to use this product in countries other than tho Unitod Stales or for any use not contemplatedby this labol. Liabilijy for patent infringement may result lrom uso orsale 01 this product outside tho**Un~ed** States, 

# / STATEMENT OF PRACTICAL TREATMENT
IF IN EYES: Hold eyelids open and flush with a gentle stream 01 waler lor at loast 15 minutes. Get modical attention, prolerably an ophthalmologist. IF ON SKIN: Immediatoly wash skin with plunty of soap and water. fF SWALLOWED: 

### Do not Induce vomiting. Promptly drink a largo quantity 01 milk, egg whites, golatin solution or 

### if tho$o are not available, drink largo quantities 01 water. Avoid alcohol. Call a physician immediately. IF INHALED: Remove victim to fresh air. 

### If not broathing, give nnlliciat rospiration. Administer oxygen il necessary, Get madical atlention.



## .ANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

# :±i PRECAUTIONARY STATEMENTS

CORAosrvE. CaulI&s eye and $kin damage. May

### be latal 

### if aDsorbed through skin. Harmlul 

### if swallowed or inha!ed,)Avoid breathing SfJI'ay mist. 00 not get

### in ay05, on skin oron ctothln9;/"p

### a~~yIrom**,~~mQstic ani~als.**  '" J 

# ,1 --""- ;,>NOTE TO PHYSiCIAN

## ~**\J~"J ~J,-,"j",** **~,.-;-J** f

## ~!t""fo--~l«,,,, j "

There 

### is no specific antidote, 

### An troatment should 

### bo based on obsorvoo signs and symptoms 01 distross in thO'**pall_e~t. Ovar~posure**  

### to materials othor than this product

### may hava occurred, 2_", ' 

# -, Victims of savare overexposure, by inhalation, should be kept under medical observation for up to 72 hours lor delayod'onsat of pulmonary edema, In a victim 01 over·oxposuro by ingestion, carolul gastric lavago is reqUired due to tho possibmty 01 stomach or osophageal perforation. This material is an 

### acid, but uso of alkaline**s~bstancos** 10 neutralize il is contraindicated,



### v 

## 'PERSONAL PROTECTIVE EQUIPMENT (PPE)

Applicators and other handlers must wear coveralls ovor short-sleevod shins and short pants, waterprool glovos, chamlcal·resistant footWear plus sockS, protactive oyewear, chemical·resistant headgear for ovarhoad exposuro and chemical-resistant apron when cleaning equipment or mixing and loading. OiSC3ld clothing and olher,absorbent materials thaI have been drenched or heavily contaminated with this products concentrato. 

### Do not rouse them. Follow manulacturer's instructions for cteaning/maintaining PPE. 

### If no such inslructions for washable!>, use detergent and hot water, Keep andwash PPE separately from olher laundry. When handlers use closed systems, enclosed cabs, oraircraft in a mannorthat moets tho roquirements listed in the Worker Protection Standard (WPS) lor**agricu~ural** pesticides (40 CFR 170.240 (d) (4·6)]. tho handler PPE requirements may be reduced or modified as specilied inthe WPS.


# 91

## User Safety Recommendations Usors should**~ash** hands bolon) aating. drinking, chowing gum, using tobacco or using the loilo!. 

### .)1 USGrs,should romov. dOlhlng immodialo/y

### if pesticide gots Insido. Then wash 

### body thoroughly and put on clean dothing. '\ ;: (**<Use~** should removo P.PE immooiatoJy after han?Hng this product. As soon as possibJa. wash thoroughly and chango into clean 

### p.

, clothing. Wash tho outside of glovos beforo remo

....mg, 

# t,

/ 

## ENVIRONMENTAL HAZARDS'/ Do no! 

### apply dirodly 

### 10 water, or 

### 10 arona whore surlaco wator Is present or to intol1idal areas bolow tho mean 

### high water mark. 

### Do nO! contaminate waterwhon dIsposing of equipmont washwalor$. 00

### not contaminate walor usedfor irrigation ordomastic purposos. 

## SPRAY DRIFT A

....

### oid spray drift. Do not

### apply when woathor conditions may cause drift. Do notallow this product to drift on to non-target areas. Drift may result in illogru residUes or injury to adjacent crops and vegot3tion, in the form of leaf yellowing and defoliation. To a

....oid spray drift. 00 NOT apply

### <lanally when wind speod Is greator than 10 mph or during periods of temperature inversions. Usoof largor droplet size wIH also reduce spray drift. AVOIDING SPRAY DRIFTAT "THE APPLICATION SITE IS THE RESPONSIBIUTY OFTHE APPLICATOR. '-'The intoraction 

### of many equipment-and·weather-rolatodfactors determine the potential lor spray drift. Tho applicator is responsible lor

considering all those factors when making docislons. 

# _The lollowing drift management requirements must be followed to avoid oll·targot movementfrom aorial applications to agriculturallield crops. These requirements do not appty to lorestry applications, public health uses or 

### 10 applications using dry lormulations. 

## "'1. Tho distanceofthe outor most nozzles onthe boom must not excoed 

### 3/4 the longth 

### 01 thewingspan or rotor. l2." Nozzles must always point ba<:kward parallel wilh the air stream and never be point

### ad downwards more than 45 dogrees. :' Where stales hav. more stringent regulations, they should be obsorved.
t The applicator should be familiar with andtake intoaccount the intormation COY/Hod in the Aerial Drill Reduction Advisory bolow:



## AERIAL DRIFT REDUCTION ADVISORY :/rThis section is advisory in nature and doas not supersede the mandatory labol requirements]. /fNFORMATION 

### ON DROPLET SIZE

Tho most ellective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provldo sufficient coverage and control. Applying largor droplets reducos drilt potontial, but will not pro

....ent drift if applications aro made improperly, or under unlavorablo I)nvironmental condillons (Seo Wind, Tomperaturo and Humidity, and Temperato/e Invors!ons). '

. J '-"CONTROLLING DROPLET SIZE \**~~**

Volume

- Use high flow rato nozzles to apply the highest prac!ical spray volUme. Nozzles with higher rated llows produce larger

# ~ "roplets.

### ~**~r."ure** - Do not exceed tho nozzle manufacturer's recommended preS$;lJres. For many nozzle types lowor pressure produces larger 

# *

droplets. Whon high&!' tlow rates are needed, use higher lIow rate nozzlos instead 

### 01 increasing pressure. Nomberof nozzles

- Use the minimum numbGrof nozzles that provide unilorm covQrago. Nozzle Orientation· Orienting nozzles so that the spray is relea.sod paraUol to tho airstream producO$. largor droplets than other orientations and is the rocommended practice. S!gnificant deflection Irom horizontal will reduclJ droplet size and Increase drill polenlial. Nozzle Type· Use a nozzletype that is designedfor the intendod llpplication. With most nozzle typos, narrower spray angles produce larger droplets. Consider using low·drilt nozzle!!. Solid stroam nozzles oriented straight back produce the large!!t droplets and thlJ lowos! drift. ".BOOM LENGTH

For somo uso patterns, reducing Ihe ellactive boom le-nglh to less than 

### 3/4 of Ihe wingspan or rotor IlJngth may further reduce drift without redUCing swath width. "'APPLICATION HEIGHT

Applications should oot be made at a height greater than 10 faet 

### abo

....e the top oftho target plants unloss a greater height is reqoired for aircraft safoty. Making applicalions at tho lowest height that is sa!!) reduces exposure 

### 01 droplets to e

....aporalion and wind. ,SWATH ADJUSTMENT**Wh~n** applications aro made with a crosswind. tho swathwill be displaced downwind. Th&reforo, onthe up and downwind ooges

### 01 the field, tho applicator should compunsato for this displacement by ad;usting the path 

### 01 the alreralt upwind. Swath ad;ulltment distance should Incroase, with incruasing drift potential (higherwind, smaller drops, atc.).

_____ 

# 92**WINO/~** Orift potential is lowest betwQon wind spoeds of 2· 10 mph. Howevor. many factors, including droplet slzo and equipment 

### typo determine drift potential at any given speGd. Application should be avoided below 2 mph duo to variable wind dIrection and high inversion 

### potential. NOTE: Local terrain can inftuenco wind patterns. Every applicator should bo familiar with tocal wind patterns and how

### ttley affect spray drift. 

### ,-,TEMPERATURE AND HUMIDITY

When making applications in low 

### retativG humidity, set up equipmont to produce targer droplo\s to compensate for evaporation. Oroptot evaporation 

### is most seVCUG 

### when conditions aro bolh hot and dry. 

### TEMPERATURE INVERSIONS Applications should not occurduring atemperature invorsion oocau5o drift potential is high. Temperature invorsions restrict vertical air mixing, which causes small suspended droplots 10 romain in a concenlratod cloud. This cloud can move in unpredtctable dirOClions duo to the tighl variable winds common during inversions. Tamporaturo invarsions are characterized by Incraasing temperatures with ahltude 

### and aro common on nights with limited cloud cover and light to no wind, Thoy begin to form asthe sun sots and often continue ) into Ihemorning. their presence can be Indicated by groundtog; howevnr, 

### ff log is not preSfant, inversions can also 

### be idantifi&d by**the~** movomont 01 smoke from a ground source or an aircraft smoko gonorator. Smoke that layors and movos latoraJly in a concentrated Y 

### cloud (under lowwind conditions) IndicattJS an invorsion, while smoke that moves upward and rapidly dissipates indicates good vnrtical air mixing.

- , 

### ",SENSITIVE AREAS**~**

The peslicide should only be applied when the potential lor drilt to adjacent sensitive areas (e.g. residential areas, bodies 01 water,

## ~ known habital lorthreatoned or ondangored spedos, non-targot crops) is minimal (o.g. when wind is blowing away Irom the sensitivn eareaS).

### ~ 

## vUSE PRECAUTIONS

Do not apply PAEpN brand Ethephon lor Cotton and Tobacco through any typo 

### of irrigalion system. Avoid spray dr;ft to nearby crops as this product wiU cause modilications in plant growth. Planr injury or reduood yields will result, Mix only the amount ofsprayyou oxpoct to uso each day. Do not allow mixod solution 10 sland ovornight. 

# DIRECTIONS FOR USE It I. a violation 01 Fedoral law to us. this producl In a manner InC1:lnslstont with Jts lab.llng, ,Read entlra label bofore using this product.

# r-~~~~'w.**=~------~** apply this prodvct in a way that will contact workers or other persons. oither diroctly orthrough drift. Only protected 

### handl"l

in the area during application. For any requirements specilic to your State or Tribe, consult Ihe agency responsible lor regulations. only in accordance with its labeling and with tho Worker Protection Standard, 40 CFR part t70. This standard contains for the protoction 01 agricultural workers on larms:, lorosts, nurserios, and greenhouses, and handlors 01 agricultural 

### It contains requirements for training, docontamination. notification, and emergoncy assistance. 

### It also contains specifIC and oXCGptlons: PtlMaining to the statemonts on this label about' porsonal protective equipment (PPE), notification to and restrictod-ontry Inlorvals. Tha rGquiramonts in this box only apply to uses 01 this prodUel that are coverod by Ihe Workor

Slandard. 

## IDo

### n~1 enter Of

### allow worker entry into troated arna$: Quring the rostricUld·enlry intorval (REI) of48 hours. (The AEI is 72 hours in aroas avorage rainfall is loss than 25 inches peryoar.}./JUJ;**~** ',-' / , PPE required lor early entry to treated areas Ihat is' permiltod under the Worker Proteelion

# ;'i:~~:~~~~:~~},I~:~:~~;~:t~~::~~~\t anything that has**b~en** treated such as plants, soil or wator is coveralls ovor long-sleeved such as any)watorproof gloves. chemical resistant footwear plus socks, and

I i headgear is also requirod.



# 93

### STORAGE' 00 not contamlnatowalnr, food, or food by 510rago or disposal. If contalnor is brokon or contonts have spHIod, follow alt procautions indicalod above and ctean up

# Ii',**'~:,?:i~~~'~~I,~;~~;~i~:~i~~:~**

# I

on fulliongth trousers, long sleeved shirt, protoctivo gloves, and 9og9les or laco shtotd. Soak up spitt with 

# I**,::.:~!~~.a::rth** 

### orother suitable mahlrial and disposo ofwMte at an approvod waste disposal facUity. DISPOSAL wastes are acutoly hazardous. Improper disposal 01 oxcess posticido, spray mixture, or finsalo Is aviolation 01 Foderallaw. wastes cannot be disposed 01 by use according to label instructions, contact your Slate Pasticido or Environmenlal Control

### ~~:,rA~o'~r,tt:h:~O Hazardous Waslo roprasontalivo altho nearest

# EPA Regional Offico lor guidance. DISPOSAL rlose (or equivalent) the empty containllfS. Then offer lor recycling or reconditioning, or punctum and dispose 01 in a sanitary

orby incineration or 

### if allowed by stato and local authoritios, 

### by burning. 

### II container 

### is burned. stay out 01 smoke

. •- REFILLABLE CONTAINERS rotum thO cootainor to the point 01 purchase ordosignated locations. This container must only bo "Ililted**w~h** PREPtl( brand lor Cotton and Tobacco. 

### 00 NOT REUSE THE CONTAINER FOR ANY OTHER PURPOSE. Prior to relftling,**lrn~!',oc'l** lor damage such as cracks, punctures. abrasions and damaged or worn outthroads on closure devices. 

### Do not leaking containers, Check lor leaks after refilling and belore tltho container is not baing reWled.



## INFORMATION VC:OTTON

A loliar spray 01 PREPN brand Elhephon lorCotton and Tobacco will accelerate opening 01 mature unopened cotton bolls and enhance**dolo~ation** which can rosult in earlier harvest with 

### an increased recoverablo yield. PREprn tmatment on cotton allows increased efficiancy Irom a once-over harvest. J'tOBACCO (FLUE-CURED): 

### A lotiar spray 01 PREpN brand Ethephon promotss early, uniform "yellowing- 01**matur~** tobacco. PREPnc roducos curing time, allowIng more efficient use 

### 01 curing barn space, 

### and increased controlover harvest schedules. /$PRAY PREPARATION

Add 

### 112 to 

### 314 ollho requiroo amount 01 water to the spray tank. Start agitation. Add Ihe required amount 01 PREP7lI brand Ethophon, 

### and the remaining amount 01 water. Prepare only 

### as much spray solution as can bo used on the day 01 mixing. Do not allow spray solu1lon to stand overnight. 

### Do not split the concentrated product on spray oquipment. or any airplane parts, ANYSPILLS SHOULD BE RINSED IMMEDIATELYWITH PLENTYOF WATER. Usa 01 

### a nurse tank is highly recommended lor avoiding possible spillS 01 COflC9nlralnd lormulation on spray aquipmont or any airplane parts

.

.

### ~ANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES ."REPN brand Ethephon is compatible with DEF'. FOlEX'#. Dropp2, Dropp1}Ulfrarn2

,

### Ginsta~2, Harvadlil· Methyl Parathion, Gll1hion', and Malatbion4• PREPN may 

### be applied in sequeoce oras a tank mixture (00 NOTTANK MIXWITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use pracaUlions and ralo poracre recommendations on labals 01 products applied as tank mix1ures or in sequence**w~h** PREP U< brand Ethephon. In somo cases slight roduction in bolt opening response has bean observed when tank mixeswith oololian!s wore used. 

### Good agilation In !hllspray tank is essential and 11 tank mixturo should not bo allowed to stand wllhout agitation lor more than 5to to minutos. Read and observe aU appropriate label use direction!> and pre-cautions lor the deloliantsand insecticides used. NOTE: UNDER CERTAIN CONDliIONS, TANK MIXTURES OF PREpnc BRAND ETHEPHON WITH DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMAT}QN OF HYPOCHLOROUSACIDS WHICH ON HEATINGWILL EMIT TOXIC CHLORIDE FUMES. DO NOT MIX PREPTloI BRAND ETHEPHON wlmAMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FQRMATK)N 

### OF TOXIC FUMES. ;/tEOUIPMENT CLEANING

Bllcause 01 tho acidic nature of this product, prolonged oxposure to spray**d(lpos~** witt damage acrylic plastics. certain paints. and metals. Rinse thotoughly with a dlltllrgel1t and walDr all oxposed acrylic plaslic.typ{! matorials (o.g., aircraft windshiolds). and painted surfaces within an hour after oxposurG to spray doposils. At tho ond 01 each day, rinsa thoroughly wilh a detergent and water alt the metal parts 01 the aircraft and the associatlld spray equipment expo$Od to tho spray deposits.



# 94

## COTTON

USE" 

## EXPECTED PREpTH 

### ONE 

### MINIMUM APPLICATION CONDITIONS 

## RATE GALLON SPRAY 

### TIMING 

### PREpm VOLUMES 

# ILBS AJ. Aere. Air

.... 

## PREpN Hot and 

### dry gO°F or 

### I 113 1.0 6 Apply when tho number of 

### Boll Openo,·· higher mature unopened bolts is Dry and 75 10 BO°F 

### 2 

### 1.5 

# • 2 suffldenl to produce tho 

### 10 desired crop. SOQ bGlow lor 

### Cool but above 

### 65"F 

### 2213 2.0 3 

### lest 

### of boll maturity, Treatment uniformly opens 

### or bolls 710 14 days oadior. 0, oil, 

### PREpTII 

### + High soil moisture 

### 113 0.25 2. 10 

### 5 Apply 4 

### to 7 days prior to 

### FOLEX· 

### or PREpm boll opening OefoUant Tank High ler@ty tevot 

### application. To b& 

### used as

Mix··· a soquonliallreatmom**w~h,** 

### or 

### not in I PREpnl bott



### .Rank conon EPN+ Dropp High soil moisture 113 

### 0.25 

### 2' 10 3 

# I**~~~~_;_IO** 7 days prior to 

### oefollanl Tank High fortUity lovel bolt opening 

### Mh,··· 

## r To be used as Rank cotton 

# Ia 

# :1**~;.:R"!o~~ ~nh.**  nOI**i~** 

### pi:",. boll


### Pre-Conditioner Hot, dry. 

### 213 0.5 12 Apply 4 to 7 days prior to 

### for DefolIation COOl, aboYO 

### 65"F 1113 

### 1.0 6 

### 10 2 dofoliant. Enhancos top


### or crop deloliation reducing dolerioralion of bottom crop Rank cotton and allows 

### lor aarlier

• Fat best performanco, by ground or air apphcauon, choose oqUlpment and spray volumes that Will Insura uniform coverage 01101lage



### and boRs

.
•• Pretreatment With Defoliants Prior to PREpn.o brand Ethephon Boll Opening Treatment: II the colton is oyorly rank or layIng down in tho mIddies and good spray coverage 01 tho botts with PREf'lM Is diJlicutt. a pretroatmont with**~** deloUants witt be uselul

### to improve 

### bolt covorage wilh PREpnI. Use dosago rates of PREpn< ro<:ommcnded for bottopening. Read and observe an approprratft labol use dirodions and precautions for the delolianl used. (can use up to lutt labol ralo lor each product)

# c-J,JC;;v~,,-

..... In California 

### and Arizona use a volume 01 no loss than 5 gallons per acre lor aerial applications. /8011 Maturity

A bott 

### is mature when 

### it is too hard 10

### bedented when squeezed between thumb and lingers. toO hard to be sliced with a sharp knife, and when the seed coat bocomes lighl brown in color. Use Llmttatlons 

### 00 not exceed a maximum 012.0 lb. ai/A lorcombined uses 01 PREpn.t brand Ethophon per acro peryear.

• Boll Opening: Do nottanl\: mix PREprn brand EltJaphon wiJh a desiccanl 

### if the colton is 10 be spindle harvesled.

• Pro-Condition lor Deloliation: Do not tank mix PREp1M brand Elhephon wilh desiccants unloss planl dosiccalion is required. Do not

- /USD a defolianl before Ihore is sulficient maluro unopanod bolls to produce Iho desirod yield {SGO General Informalion section on 

### ,"/ how to test for bon maturity. 

### 00 NOTAPPLY PREpnI BRAND ETHEPHON IF RAIN IS EXPECTED WITHIN 6 HOURS. RainlatJ within 6 hours of applicalion may roduco product performance. Do nol plant anolher crop within**~o** days aftertrealmonl. Small gl{1ins planted oarlior Ihan I month or inlercropped wilh lho colton crop to which PREpw witt 

### be appliad may only bo used as COYer crops and may not be harvosled lor lood or loed, PREpnI may cause yottowing andgrowth inhibition of IrealedsmatJ grains.

## ~~HEN TO HARVEST COTTON 

### Do not harvest colton soonerthan 7 days aftor a troalmonl with PREpm brand Elhephon. Observe Iho Irealedcrop and harvest whon optimUm boll oponing has boon roached. Too early harvest mighl r"ducs tho full advanlage 

### of tholrealmenl and 100 lale a harvest may resull in reduced quality and loss01 

### lint which 

### ¥lilt drop lrom Ihe planl. 

# 95

### Crop Situation

Application

Application 

### PREpTU Pints/Acre

1 1/3



### 11(3-2213

USE LIMITATIONS 

### Spray Volumos 

### Oallonsl
50

40 

# TOBACCO

SpecHlc Olr.ctlon.



### Use drop nozzles. ChooSB gpa at 

### 35-40 psi and at tractor speed 2·3 

### 2 nozzles per row; one on each side orthe row dropped low

### onough to dirOCf the spray to tho loaves to 

### be ripened and harvested. Thorough spray 

### i 

### With 

### a directed spray, 

### bo sure to harvest all loaves 

### ; Troa! only whon leaves I 

### remaining leaves ar. maturo, spray several 10t,.eeo described underthesection ·Proper Time 01 Troa!mont: Usa the lower rate 

### in a normally mature crop whon experience indicates that minimum ripening inducement is required. Use tho higher rato when tho crop is heavy and has a tendency to be 

### more rank or when temperatures are lower than normal. Always test spray to detormine 

### if tho tobacco is mature enough to respond to treatment with PREpm Apply ovor-tho-top PAEpl'" spray as a tine mist using: throo nozzles (ono nozzte tips over the canter of the plant, and one on oach side) $0 all leaves are covered thoroughly, similar to tho I 01 systemic sucker I


### Do not apply PAEpDI brand Ethophon to immature loaves as this clln result in unsatislactory coloring, woight loss and reduced loal quality. 

### Do not allowthe CfOptO ovor r'lpon 'In the tiold alter using PAEpu. brand Ethopoon. since this may causo somo roduction in yield and quality. 00 not treat before anticipated major storm which could prevent harvest and res}l.It,in crop**~ss:** .. '

. 

### 00NOTAPPLY PREpn.c BRAND ETHEPHON IF RAIN IS EXPECTED WITHfN\6,HOURS. "Rainfall Within 6 hours ofapplICation may 

### i. reduce 

### product periormance.) ;.

### jii~l~_**v....-~, ~**  ", 

### Do not use PAEPT"'lxand Ethephon with

### add~ivos other than recommendod on this label.' 

### Do not plant anothercropwithin 30 days altertreatmont.

### /~;;"'/" 

### Do not oxceod 2lbs othaphon per acre per year. .' vA'PPLlCAnON TIMING .'-

Successful results with PAEpn.c brand Ethephon call for treatmont when loaves are maturo, not ovorty rank green when sprayed. To ouily determine the proper troatment timing and the number of leavos per slalk ready for harvest, tost spray several plants in more ..-..!han one location In each Held and observe the reSponse. Mature leaves 

### will begin to yellow in 24 to 72 hours. Tost leaves that fail to .,.weflow 

### In 72 hours are not mature and aro not ready for PAEpN treatment Wait'8 few days to permit lurther natural maturing, then make anothor to51 spray or -maturity- chock. Toavoid quality 10$$ and or possible leafdrop. harvost an¥ yellowed leaves prior to application. Use lower rates under most conditions" limit use of higher ratos to cool (below 6SF at tho time

### of treatmont) slow rlponing conditions. Whon you have conlirmod tho desired numbor of leaves por plant that will color, you can dotermine the number of acros to troat in order to fill the bam. Preparo your test spray 

### by mixing onetoaspoon of PREP1).1 brand Ethephon in t quart of water. Spray each test plant with abolJt t oz. ofthis mixturtl:, covering aU leaves with a tino mist. PAEprn will not co_lor immature sprayed leaves. 

### tAYHEN TO HARVEST

All maturo, sprayed loaves will begin to colorwithin 24

### to 72 hours altor PREpm brand Ethophon application. Theyellowing procoss 

### i, woather dependent; cool weatherwill detay, while hot, sunny weathorcat'l spood up the procoss. Harvasttreated tobacco when leaves have reached the desired color inlensily. Harvest can commence 

### 48 hours alter PREpm brand Ethephon application. To detonninQ harvest timing and avoid quality loss or loal drop, closoly monitor trealed crop and weather conditions. v,CURING PREpm BRAND ETHEPHON TREATED TOBACCO

Curing proceduros are as much an art as a science and each curo must be judged on the basis of tobacco condition, Interval between troatment and harvest, woather and type of curing facility boforb prescription temperature and ventilation schodulos can be established. To obtain maximum quality, carl) must be taken to observe and control the curing process closely, espocially during the lalo ·coloring" and earty**"drying~** stagos 01 the loaf. PREpn.t brand Ethephon treated tobacco will have started Ihe coloring process when harvested, reducing tho time required in tho coloring phase ofcuring, Treated tobacco shOUld be dried faster. Iftobacco lea'lo$ are groen or contain some groen when harvested, 

### it may be nGCGs.sary to color them lor a few hours. Ifthe leaves are completely yellow. temperature and ventilation must 

### b& adjustlMl in a mannerto dry tho tobacco as fast as possible without scalding. Once tho loaf is dried (3/4 dry),

### you should follow normal procedures for curing. Since PAEpN troated loaves curo fastor, treated and untroated leavos should nol becured together in the same barn. 

# 96

# LIMITED WARRANTY AND DISCLAIMER The manufacturer warrants (a) Ihal this product conforms 10 Ihe chomical description on Iho labol; (b) Ihal this product is reasonably fit 

### for Ihe pUrpc.10S sol forth in Ihe directions for use whon 

### it is used in accordanoo**w~h** 

### such directions; and (c) 

### Ihal Ihe dirGC1!ons, warn!{lg and olhor stalomenls on Ihis label am based upon rosponsible oxpons' oyalualion of reasonable 10siS 01 offectiveness, of loxicity 10 laboralory animals and 10 planls, and of residues on 

### food ClOPS and upon roports of field experience. Tests have nol beon mado on affvaoollo$; or in all states or under aU conditions. lliE MANUFACTURER NEITHER MAKES NOR INTENDS. NOR DOES IT AUTHtJRlZJ::. ANY AGENT OR REPRESENTATIVE TO MAKE. ANY OTHER WARRANTIES, EXPRESS OR IMPLIED. AND IT 

### EXP'

.....EXCLUDES AND DISCLAIMS ALL IMPLIED WARRANTIES OF MERCHANT·ABILITY OR FITNESS FOR A PARTICULAR PUR }SE. THIS IARRANTY DOES NOT EXTEND TO, AND THE BUYER SHALL BE SOLELY RESPONSIBLE FOR, ANY AND ALL LOSS OR**DAM~** 

### iE WHICH RESULTS FROM THE USE OF THIS PRODUCT IN ANY MANNER WHICH IS INCONSISTENTWITH THE LABEL DIRi .OOS, WARNINGS OR CAUTIONS. 

### BUYER'S EXCLUSIVE REMEDY AND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY FOR ANY AND ALL CLAIMS, LOSSES, DAMAGES. OR INJURIES RESULTING FROMTHE USE OR HANDLiNGOFnilS PRODUCT, WHEniEROR NOT BASED IN CONTRACT. NEGLIGENCE, STRICT LIABILITY IN TORT OROniERWISE SHALL BE LIMITED, ATTHE MANUFACTURER'S OPTION, TO REPlACEMENT

### OF, OR THE REPAYMENT 

### OFTHE PURCHASE PAICE FOR, THE QUANTITYOF PRQDUCTWlTH RESPECTTO WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHALL MANUFACTURER OR SelLER BE LIABLE FOR SPECiAl INDIRECT OR CONSEQUENTIAL DAMAGES RESULTING FROM niE USE 

### OR HANDLING OFTHIS PRODUCT, WHEN USE 

### OR HANDLING IS NOT IN 

### ACCORDANCE WITH LAIlEL DIRECTIONS. NOncE TO BUYEA Purchaso ollhis product does not conler any rights under patenls governing Ihis product or Ihe usa therool in counlries oulsid$ 01 Ihe 

### fltt'nil&d Siaies

.



# •

1

### DEF and GlJlhion are registered trademarks of BayerAG, G&rmany. 2Dropp and Ginslarare regislerod trademarks and Ukra is a Irademark 01 AgrEvo. 'Haf\lade is a registoroo lrad.mark01 Uniroyal Company.**~Malalhion** 

### is a Iradomark 01 American Cyanamid Company.

RhOna·Poutone Ag Company P.O. Box 12014, 2 T.W. Aloxandor Drive RHoarch Triangle Park, Norlh Carolina 27709 PREP is Ihe Irademark 01 RhOne-PoulenC. FOLEX 

### is aregistered trademark 

### of Rhono-Poulenc

. PREpThi brand Elhophon for Cot'.on and Tobaa::o (PENDING) Submitted 1116196, 

### Resubmittod 1131/97.



# 97

# , ,


# -



# •

• 

# I N AN IRONIC TWIST TO THE CURRENT TEXAS DROUGHT, some cotton growers have shunned a moisture-conserving cultivation practice because they lacked irrigation water. But many who invested water in the practice this winter are benefitting from improved stands, fewer blown-out fields and potentially higheryields.

6 COTTON FAAMING JUl..,.. 1!l96 

## llYV1CKYBOYD

The practice, called conservation tillage or terminated wheat-cotton, involves planting a cover crop of 

### wheat or rye in the fnll after cotton 

### harvest. The seeds are sown in 28 to 30 inch!'!:; of the furrows and llides of 

### ·to-inch rows.**i<~aving**

### the top bllre.

Grower;; allow the wheat or rye to tiller until two to 

### four weeks before 

### planting, when they burn 

### it down 

### with a herbicide such as Roundup_ If 

### the wheat isn't tillerillg, it**"mdt$~** 

### aller the herbicide application and 

### does not provide enough residue to hold

### the soil and retain soil moisture.



### Because the top ofthe bed is bare, growers don't need special planting equipment to slice through 11 

### cover erop. IU'IyS 

### Wayne Keeling,**sys~ms** 

### agronomist with the Texas Agricultural Experiment Station in 

### Lubbock.Texas.

The lack oftop cover isn't**h~rge** 

### enough to promote wind erosion, a common problem in part:aoftheTexas Panhnndlo. Growers nlJro don't have to 

### fight n 

### cover crop regreening and compel,.ing with cotton seedlings, according to**~1ing.**



### After**cott~n** 

### harvest, growers plant wheat into the stalks. The cover not only trnps winter moiature but also holds the soil down during strong wind 

### stonnS'.

In Texas, heavy rains !!1ick over bare 

### fields ofsandy soil. When 

### strong winds fnllow, topJroil is 

### blown away.**~Blow outs~**  

### of entire fields. are not uncommon.



### Awheator rye 

### coverrequires II pre

### irrigation before piantingor irrigation Jor stand establishment. For thnt rea· 

### Jlon, some growers opted against it lasl,. winwr 

### l«auoo oflow water supplies. 

# 98

# r



# •

• TEXAS RAINFAU r1r 

### the ;
. .'ast 

### tbree**~'cnrs, T~:;;a;;**  

### h,w received**II;!~s-lfHtn-normal** 

### r,:unfull. The problem came to i1 

### head In 

### law 

### 1995 when fall nuns never camt',

The lr(lOd continued inti) 1996 with only**scan~** 

### ramfall in April and May

- normally the wettest month5 of the 

### year, :\1any areas oi the l!.taw Cltli'gO

### rized as having**~moderute** 

### uroughC conditions III 

### l'!nrly 1996 have neen 

### reclassified as being III

### a severedrought.

-Orought makes 

### this less ofa.n optIOn 

### than what 

### it might 

### be uncler normal ctrcumstanccs,F K(Wling SIlYS, -:\lm;t people in the sys

### tem aredoing It

### underirrigahon,"

Ouring four yellrs 

### of large-scale lield trials at Lamesa,Texas.conducted in 1991 lind from 1993 tll 

### 199;3 by the Texas Agricultural**Exlcn,~i(llt** 

### Service. terminatM wheat-colllJO had good yields**(~ee** 

### bmo,

Under drylnnd conditions, the**U'r~** 

### minated wheat·cott-on dldn't perform
as well. with field,; yu;;lding a**four~** 

### year average of 234 pounds an acre, Conventional tillage yielded 249 pounds an ocre and solid plnnting using minimum tillage yielded 364 pfJUndll perncrf'.


### IRRIGATION IS BENEFICIAL

All things. considered. Keeling believes terminated wheat-cotton under irrigation isthe bestoptioll,

"Generally, Yields (of the termmat· ",d wheat-cotton! have been equal to 

### or n little bit higher than conventional," he says. "We have had three ttl four yellrs of below-average .minfllil,. and it still yielded equul to convenrionoL I think ifwe ever get back inw
an uverage wateryear, that is whIm it 

### wilJ renlIy t"1)me**Oll.~**



### Alan Duncan, mdependent farm implement so-IllS representative based in Plainview. Texas, says terminated whellt-cotton is slowly catching on, espeeialJy in areas with sandy soil,**~Jt's** 

### increaSing eVl'ry year nnd I think, oven with the drought. it's**gaining.~** he**~ays,**



### As many as 30 pcreent ofthe grow

### ers In 

### the sandy solis around Seminole nnd Brownfield U!W 

### a cover. But in the Lubbotk area where soill>
are hl':'avler. ff>wer have adopted it. Duncan adds.

Butch Harrell. who farms (lcnr Hale**C~nt.er** 

### nonh of Lubbock. knows Ihe benefits of temunated wheat·co. ton. lIe h(l!! nbout. 122 acres planted with C()\'('r 

### under c('nu>r-pivnt lrriga· tlOn. IIis r<!maming 2,10 acres are con-

....entlonally tilled.

A recent rainstorm dropped a 3/4 

### inch on hiS fann, and two hours Inter Ihe sun came aut. "licking**o~'er** 

### the !loil. The v.ind then liLarted blowing at

50 miles per hour. "I lost tll"vcral acrcs (of convent!onal) hffausc the

.... indjust blew it up," Harrell says. "But with the no· !ill. I dIdn'teven worry about**It.~**



### The rover also hal> helped save soil mOISture, In the fields WIth a good**,~()ver,** 

### h" used his cuswmary 

### 314 inch nnd had good standestablishment.

Harrell.**wh~'s** 

### been experimenting' with ",over crop!; find what he calls**~no·ttW** 

### for the p!Cit five years, says the only drawback is the high cost of herbicides neededfor burndown_**~You ha~'e**  

### to have an awfully good**YH~ld** 

### to make it work

- that is the problem.**~** 

### he says. Two bllieli every yearwould 

### be greal. Butlastyear, we were happy to 

### get600 pounds. M



### .James Simpson, a cotton growf>r
near Lubbock. decided not to 

### plant a rover this**win~** 

### ter because well levels were half of what they were four 

### yeanago.**~l** 

### wiah I still had some wheat. because we would still have our crop," Simpson says.

Thesame winds that blew out parts ofHarrell's crop alro struck SimptiOn. who lostabouthalfofthe480 acreshe had**und~r** 

### cMwr-pivot irrigation. In late

### Mny hewas trying to 

### replant.

Duncan .says one deterrent UI 

### grow_ ers have to plant a cover 00 

### late they may not get adequate residue production by the time they have to 

### burn it down for spring planting.

# • U, EI'o'Vl1t«"ME.

.. 'TAL I'ROTECTlON AGENCY EPA Rq: NuJnb<,t. l'>$ of**rn~:mcc:** :cI'rt O

### ""'>r". Off« rX I\$lki& I'rograrm 

## 264-418 

## JUl 

## !7 1997**P:'1:I!md~'~** PI,>jlOnlH7505Ci 

### ;- 

# ..,.**~** .u)! 'M" Sr

. SW

# \~)**W:o!ltin~t<m,** 0 C**2~60 T~mrM**  l!suMICc' 

## Unconditional

+»"t

# ,.,..,.t V 

## NOTICE OF PESTICIDE,



# --- Registration _X_ 

## Reregistration N>..'W <If 1'

.. 

## \1<',* I'm&'<;:I'Pl-ep 

## brand

(\;r>!kr Fll'ltA,**~** :tmrndt'd) 

## Ethephon for Cotton and 

## Tobacco
NlI.IIlI' and Addr

.. s

### <,r**Rt~:1t.1;W (i",I~M**  7JP C.-.k), 

## Rhone-Poulenc AG 

## Company P.O. Box 12014, 2 

## T.W, 

## Alexander Drive Research Triangle Park, 

## NC 27709

Now.**C~o** ill bbdill; ditfmnt ill HlmW!Ce frnm Ilw**lI(C~** inCOOII«limI with II,n**~iMIIluo** toUl;\ Ix-**~ul>lMkd!(l ~**  1Ii:tepfI:dby the Rql«flIIJOI'> Dr-ItkinpMr III\lltof!k**~I** in romn><:ttt In:my**t"'rC$~** 00lhl!; ptl.>duCl.;lways I'C'fer 10 the**lIho~,t** EPA**~i1If/lliM** numb«**o~** th<: bti", m ;"I(>lTllllliun**f~r()iI;htd** by lhc Icti,trW., W**~** na.Ill<'>.J pcll>ci/k " hn.by rquttrw!rtttt,ll.:r«l undo" !be Ft<knllll;Oo;;lIdde. F\lIIjIO:id<:

... .<I R<xkntkKk ML 

# • Rq:utnlWn Ii In 110**w~y** to lK :00",:.

..

'<1 $ ""**mOOrn:mrr~** (>1 remmmcn.:I.Mmn Mtho. P'OI.Iu« by the**Ag~!:ICy.** 10 onkr II! p''Jl'Xt**~th** and!ht co.;ujtlJl)CnI, Iht**Adll\ll1isrr~r.** on hi:! IOOOiJO. !Ny !II ""y rime !wpmJ (>f wc:llW: rqarratiMof l palkKk in**acC<l~** with the Ao. lbc-**~tptaOCc** or My rwnc In conr.eaiM with**~** rOii>lr.iIion of**~** P'oo:i1lct un<ltr ill" A<I**i~** 001 10W**oo"'tnJ~d** ..**iivm~** Iht rttlSUiII\l**~** rijl" ru "dmj'eUI<; <If

### u.. name« l<) ir$ usc if11 Iw bo:r.**~o\tr~d** by lXhr..


## Based on your response to the Reregistration Eligibility Document, 

## EPA has 

## reregistered che 

## product listed above. Enclosed is a 

## copy of your label stamped "Accepted, " This action is 

## taken under the authority of section 4 (g) 

## (2) (c) 

## of the Federal Insecticide, Rodenticide Act, as 

## amended. Reregistration under this section does not eliminate the 

## need for continual reassessment of pesticides. 

## EPA may require submission of data at any time to maintain the registration of your produ(.'t.

:

. 

# •

Sigrw-

..re orApp",.,-ir,g O(fi"ral DiU: 1!' 

## i7 

## 1997



# .,
"rm 'I\H) 

# 100

# PREP TM 

# brand Ethephon FOR COTTON AND TOBACCO
For Commercial Use Or Agricultural Use Only. Not For Residential Use 

# •••• ACTIVE INGREDIENT: Elhephon**(2~ChloroethyJ)** 

### phosphonic 

### aCId'

.....................................""

........:•....55.4% INERT INGREDIENTS:

................................................. 0<

................................... , •••**-.~~.~;~.:.** •••••••• ,. •••**~** ••

### ,,44.G%



# . . . 

# . 'This producl contains 6 pounds ethephon per gallon.**~** 

### Reg. No. 264-418 

## •••••• 

## • 

## • 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

SI usled no enliende la eliqucln. busque a alguien para que SI! la expltque a usled en delalle, (II you 

### do nol understandthe label, find someone 10 explain 

### It to you in de/ail.) 

# •••••• •

• • 

## •• •• •



# ..., ••• 

## • ••



# ..**.FF'iio"rlMi:iE~DiiIllc~A~LClA\ini<dI"TIBMA1iN~Si1pgOl]Rii:TIAA1T]IQQijNEE;;m;;;e;:;rgg;e;;niCcT.;.;;.i"i:QlINUL::'y[(c':i.iill"l 2244iH:r.o;iuJrr:ss~AAiD5i.;;yi11:;·.iiioiOo::·3ii3i44:j·7'55"i777-**  For PRODUCT!lS..E. Information Call 1-800-334-9745 The use 01 this product lor a variety 01 plant growth regul<lHon uses are protected by United States and foreign patents Including 

### U.S. Palent 4.240,819. No license is granted /0 use this product in coull/ries other than tho United Stales or for any use nol contemplaled 

### by this label. liabilityfor patenllnlringumenl 

### may result from use or sale ol/hls product outside the United Siales. 

# FIRST AID
IF IN EYES: Hold cyelids open and /lush with a gontle Siream 0/ water lor 1I1Ioa51 15 minutes, Gol medical attention, preferably an ophlhalmologist IF ON SKIN: Immediately wash skln wilh plenty 01 soap and water. Get medical altention. IF SWALLOWED: Do not induce vomiling. Promptly drink a large quantityof milk, oggwhites, gelalin solulion or illhase are not available, drink largo quanlities 01 water. Avoid alcohol, Call a physician or Polson Control Ccnler. NOTE TO PHYSICIAN Treat symplomalicnlly. Consideration should be given to Ihe possibility Ihal overexposure !o materials olher Ihan Ihis producl may hnve occurred. No specific anlidote is available. Probable mucosal damage may contraindicale Ihe use 01 gastric lavage, 

# • PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS CORROSIVE. Causes irreversible eye damage andskin burns. Harmlul il swallowed orabsoftlod through skin. Do nor gel in eyes, on skin or on clothing, 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Applicators and olher handlers must wear coveralls over short-sleeved shills and shorl pants, chemiCa!·resislanl gloves (such as Nilrile, Bulyl, Naoprene andlor Barrier Lamlnale), chcmical'resislant loolwenr plus socks. prolective eyewear, chemical·resislanl headgear lor overhead exPosure and chemical·resfstanl apron when Cleaning equipment or mixing and loading. Discard clolhlng and olhor absoftlent malerials that have bean drenched or heavily conlaminaled wilh Ihls producls concenlra!e. Do not reuse Iham. FollOW manufacluror's inslruclions lorcleaninglmainlaining PPE. II no such fnslrucllons for washables, use delergenl and hOI waler. Keep and wash PPE sopar:llely lrom olherlaundry, When handlers use closed syslems. enclosed cabs. or aircralt in a manner Ihat meolS Ihe requiremenls lisled in Ihe Worker Proleclion Standard (WPS) for agricullural peslicides 

### [40 CFR 

### tiO.240 (d) 

### (4-6)j, Ihe handler PPE rcquiremenls may be reduced or modified as specitied in rhe WPS. 

# ACCEPTED
i 

## I 1997



# 101**,-----~~-~**...•**~** 

## --------------

User Safety Recommendations Users should wash hands before eallng, drinking, chewing gum, using tobacco or using tho toilel. 

### Users should remove clothing Immediately it 

### peslic!de gets 

### Inside. Then wash body thoroughly and put on clean clothing, Users should remove PPE immediately aHor handling this producL As soon as possible, wash thoroughly and change inlo clean 

### clothing. Wash the outside**o~9loves** 

### belore removing.



# . ...... ENVIRONMENTAL HAZARDS


# ........ Do not apply direcUy 10water, or 10 areas whore surface waler is present or 10 intertidal areas below

# tire intAtn high 

### waier mark. conlaminalewaterwhen disposing of equipmenl washwalers,

.. .. : •••:

.. 

### Do noJ contaminate water used lor irrigation ordomestic purposes. 

## SPRAY DRIFT 

# ...... .. • •

•• •••



# .......

• • • • •



## •• Donol

Avoid spray drilL Do not apply when weathor conditions may cause dnff. Do not allow this product 

## ie-drifton to non.ta!£!et areas. DrOt may result in illegal residues or injury to adjacent crops and vegetation, in the lorm 01 leal yellowing and

### detoH~ion~ 

### to avoid spray drift, 00 NOT apply aerially when wind speed ts groater than 10 mph orduring period!> oftemperature inversions. OMbt larger droplet size 

### will also reduce spray drift,

..... : AVOIDING SPRAY DRIFT AT THE APPUCATION SITE IS THE RESPONSIBILITY OFTHEAPPLICATOR. 

## ••
The interacllon 01 many equipment-and·weather·relaled laclors delermine the potenliat lor spmydrift. The appHcator is responsible tor

• conSidering all these factors when making decisions, The tollowing drilt management requirements must betollowed to avoid oll·target movement from aeriat appijca![ons to agricultural tield crops. These requirements do not appty to lorestry applications, public heaUh uses or to applications using dryformulations. 1 The distance ot the outer most nozzles on Ihe boom must not exceed 314 Ihe length 

### oJ the wingspan or rotor. 2, Nozzles must always point backward parnUel with the air stream and never be pointed downwards mora than 45 degrees. Where stales have more slringent regulations, they should be observed. 

### The applicator should 

### be lamltiar with and take into account the intormation covered in the Aerial Dr'dt Reduction Advisory below: 

## AERIAL DRIFT REDUCTION ADVISORY [This section is advisory in nature and does not supersede the mandatory label requirementsj. INFORMATION ON DROPLET StZE The most eUeclive way to reduce drill pOlential is 10 apply targe droplets. The besl drift management strategy is to appty tho largest droplets Ihat provide sutlicient coverage and control. Applying larger droplets reduces drill potential, bul will not prevent drill II appilcalfons are made improperly. or under unfavorable environmental cond[lfons (See Wind, Temperature and Humidity. and Temporature Inversions). CONTROLLING DROPLET StZE

• volume

- Use high How rate nozztes to apply the highest practical spray volume. Nozzles with higher raled Bows produce larger roplets, Pressure· Do not exceed tho nozzle manulacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higher1I0w rates are needed, use higher How rate nozzles instead 01 increasing pressure. Number ot nozztes

- Usc the minimum number 01 nozztoo that provide unilorm**covera~.** Nozzle Orientation· Orienting nozzles so Ihat the spray is released parallel to the airstream produces larger droplets than olher orientations and is the recommended practice. Significant deflection from horizontal wilt reduce droplet size and increase drift potential. Nozzle Type· Usa a nozzle type that is designed tor the intended applicaHon. With most nozzle types. murower spray angtos produce tafger droplets. ConSIder using low·drill nozzles. Solid stream nozzles oriented straighl back produce the largest droplcts and the lowest drill. 

### 800M LENGTH For some use pauerns. reducing the eJtective boom lenglh 10 less Ihan 3f4 ot tho wingspan or rotor length may turther reduce drill without reducing swath widlh. APPLICATION HEIGHT Applications should not be made at a height grealer Ihan to teet abovo the top of the targot plants unless a greater height is required for aircralJ salety. Making applications at th.e lowest height Ihal is sate reduces exposure 01 droplets to evaporalion ard,wind. SWATH ADJUSTMENT When applicalions arc made with a crosswind, the swath will be displaced downwind. Therelore, on the up and downwind edges 01 tho Held, the applicator should compensate lor this displacement by adjusting the path 01 the aircraft upwind. Swath adjustment distance should Increase. 

### with increasing dritt polenlial (higher wind. smaller drops, etc.).


# 102WINO Drill potentia! is lowesl between wind speedS ot 

### 2

- to mph< However. many faclors, including droplet size and equipment type determine drirt potential at any given speed. Application should be avoided below 

### 2 mph due to variable wind direction and high Invor$ion potential. NOTE: Local terrain can influence wind patlern$. Every applicator should be ramiliar with local wind patterns and how they aUect spray drill. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, 

### set up oqUipmenl to produce larger droplets to compensate lor**ev~poration.** Droplet evaporatton is most severe when conditions are both hot and dry. •••• 

### •••• TEMPERATURE INVERSIONS •••••• • 

## • 

## •• Applications should not occur during a temperalure inversion because drift potential is high. Ternpemlure ill.versioos I'Ktrlct vertical air mixing, which cau&es smail suspended droplels to remain in a concentraled cloud. This cloud can mt".

### to.!ilnpre~,a~·directions due to the light variable winds common during inversions. Temperalure inversions are characterized bY.illcreasing. Lem",eratures with allitud& and are common on nights wilh limited cloud cover and light to no wind. They begin 10 lorm

### NioJ/'/, sun sets and:bllen continue into the morning. Their presence can bo indicaled by ground log; however, 

### if log is not presenl,**invewOQ\~an** alsO**~identi!jed** by the movement 01 smoke Irom 

### a ground $Curce or an aircraft smoke generator. Smoke that layers and moves later'lUy 11".a concentrated cloud (under tow wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissIpates i"'ii!'!,t1"l good vertical alr mixing. SENSITIVE AREAS 

## •

## •• • ••

•• The pesticide shOUld only be applied when the potential tor drill to adiacenl sensitive areas (e.g. reSidential areas. bodies 01 water, known habitat lor threatened or endangered species. non·tergot crops) is mInimal (e.g. when Wind is blowing away trom the senslilve _areas). 

## USE PRECAUTIONS Do not apply PREP'" bland Elhephon tor Colton and Tobacco Ihrough any type 01 irrigation syslem. Avoid :>pray driltto nearby crops 85 this product win cause modifications In planl growth. Plant injury or reduced yields wlU result Mix only the amount 01 spray you expect 10 use each day, Do not allow mixed solution to stand overnight. 

# DIRECTIONS FOR USE It Is a violation 01 Federal law to use this product 

### in a manner Inconsistent with its labeling. 00 not apply thrs product rn a way that 

### wI!! contact workers or other persons, erther directly or throu9h drift. Only protected handlera may be In the area during application. For any requrrements specific to your State or Tribe, consult the agency responsible for pesticide regulaHons. Read entire tabel before using this product.

Use this producl only in accordance with ilS labeling and with Ihe Worker Protedion Standard, 40 CFR part t70. This standard contains tor the protection 01 agricultural workers on farms. lorasts. nurseries. and greenhouses, and handlors 01 agricultural

. i It contains reqUirements tor training, decontamination, noUilcat!on, and emergency assistance. It also conlains spocillc and except10ns pertain'lng 10 the statements on this label about peJsona:1 proteclive equipment (PPE), notilication workers and rastricied-enllY intervals. The reqUirements In this box only apply to uses otthls product that**ar~** covered by ihe

# W,,,k.,.! Protection Standard. 00 not enter or allow worker .ontry inlo treated areas during ihe reslricted-entry interval (REI) 01 4B hours. The REI is 72 hours in where average raintall is less than 25 inches peryear. PPE required tor early entry 10 treated areas Ihat is permitted under the Workor Prolection Stand;ud and that involves contact it anything that has been treated such as plants, soil or water is coveralts over long-sleeved shirt and long panIS, chomical resistanl gloves such as any waterproof.gloves, chemical resistanl loolwear Plus socks. and protective eyewear. For overhead exposure, chemical-resislanl headgear is also required.



# 103

### ""----

STORAGE Do not contaminate water, food, or feed by siorage ordisposal. 

### If container is broken or conlents have spilled, follow aU precautions indicatod above and clean up Immediately. Before cleaning up, put on full length trousers, long sleeved shirt, pro/ectlve gloves, and goggles or face shiefd. Soak up spill with absorbent media such assand, oarlh or other suitable material and dispose ofwaste al an approvedwaste disposal facility. :.-. 

### PESTICIDE DISPOSAL •••• Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or

## ri~;~.ru·i a

## vjo.Laljo~.of Federal law, If these wastes cannot be disposed of 

### by use according to label instructions, conlact your Slate P.oPJi¥IPP or 

### EOfifMmenlal Conlrol Agency or Ihe Hazardous Waste repro.sentalive at Ihe nearest EPA Regional Office lor guidance. • ••• •••• CONTAINER DtSPOSAL ••••• 

## ..! Tripfe rinse (or equivatent) Ihe empty containers. Then offer for recycling or reconditioning, or pUf"lCll,tU-eoand dispose of in a sanitalY landllll, or by Incineration or if allowed by state and local authorities, by burning. If container is burned, stayout ol.smlW:t. RETURNABLE

- REFILLABLE CONTAINERS ••

## !..• After use, return the container to the point 01 purchase or designated locations. This container must only be relillet!:\ti1h fREPw brand ElhephOn for Cotton and Tobacco. DO NOT REUSE THE CONTAINER FOR ANY OTHER PURPOSE. Prior to Milling, inspect for damage such as cracks, punctures, abrasions and damaged or worn out threads on closure dovices. Do not reliU or leaking containers. Check lorleaks after retilling and before transportation. If the container is not being refilled,



## GENERAL INFORMATION COTTON A foliar spray 01 PREpnl brand Elhephon lorCotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhanco defoliation which can result in eartier harvest with an increased recoverabfe yield. PREP'''' treatment on collon allows increased elflciency Irom a once·over harvest. TOBACCO (FLUE-CURED): A loHar spray 

### 01 PREpN brand Ethephon promotes early, uniform 'yellowing' 

### 01 mature tobacco. PREpw roouces curing time, allowing more efficient use of curing barn space, and increased control oYer harvest schedules. SPRAY PREPARATION Add 

### 112 to 

### 314 of the required amount of water to the spray tank. Start agitation. Add tho required amount 01 PREp!"" brand Ethephon, and tho remaining amount of water. Prepare only as much spray solution as can be used on tho day 

### 01 mixing. Do not allow spray solution lostand overnight. Do not spill the concentrated product on spray equipment. or any airplane parts. ANY SPIllS SHOULD BE RINSED IMMEDIATELY

### WITH PLENTY OFWATER Use 01 a nurse tank is highly recommended lor aVOiding possibte spills of concenlrated formulation on spray equipmenl or any airplane parts

. 

### .rANK MfXTURES WITH DEFOLIANTS AND INSECTICIDES

### ~REPw brand Ethephon is compatible with DEF1, FOLEX®, Dropp", Harvade3. Methyl Parathion, Gulhion I, and Mrualhion4

.. PREP'" may be applied in sequence or 

### as a tank mIxture (DO NOT TANK MIX WfTH DESICCANTS IF COnON IS TO BE SPINDLE HARVESTED). FoUow all applicable use precautions and rale per acre recommendations on labels 

### 01 producls applied as tank mixtures or in .sequence with PREP '1M bcand Ethephon. In some cases slight reduchon in boll opening response has been 

### observed when tank mixeswilh deloliantswere used. 

### Good agitation in the spray tank fs essentiat 

### and a tank mixture should not be allowed to stand without agltati"on lor more than 

### 5 10 to minules. Read and observe all appropriate label 

### usc directions and**pr~cautions** for the defoliants 

### and insecticidos used. NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREp:" BRAND ETHEPHON WITH DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH ON HEATING WILL EMtT TOXIC CHLORIDE FUMES. DO NOT MIX PREpr" BRAND ETHEPHON WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMAT!ON OF TOXIC FUMES. EQUIPMENT CLEANING Because 01 the acidic nature of thiS produCI. prolonged exposure to spray deposit will damage acrytic plaslics. certain paints, and metals. Rin.so thoroughly with a delergent and water all exposed aClYlic plastic-type materials (e.g., aircraft windshields). and painled surfaces within an hour after exposure to spray deposits. At the end of each day, rinse thoroughly with a detergent and waler all the metat parts 

### 01 the afrcraft and the associated spray equipment exposed 10 the spray deposits.



# 104

## COTTON

USE EXPECTED 

### PREpw

## ,~ 

# !;, SPRAY APPLICATION 

### CONDITIONS 

### RATE VOLUMES TIMING 

### (Gals/A)

pi 

# .f. Ilas A,1. Acr•• Air'" 

# :

# ... PREP'" HoI and

### dry 80"For 

### 1 113 

### 1.0 6 .I.pply when-the numbor 01 

### Boll Opener' higher 

# , ,/.lnopenad bolls is 

### Dry and 

### 75 to 

### 8O"F 

### 2 1.5 4 

### i 

### '6- Ihe 15

- 50 

### 2,5 i

## ldOf~~!i;~ee below lor Cool but above 

### 6soF 

### 2213 2.0 3 

## ••**~st** 

### maturily, I 

### opens 01 

## •• ,olls**,,~** I I 

### PREP'" + High soil moisture 

### 113 0.25 

### 2. 15

- 50 5·

# to Apply 4

# ~:~~!r;:tnor to 

### FOLEX:>: 01**PREPH~** opening Defoliant Tank High lertilily level 

### application. bo used as



### Mix" 01 

### a**se1~~~:lllrealment** 

### with, not in of PREP'''' boll 

# IAsok collon I rnO' 

### Oropp High soil moisture 

### 113 0.25 

### 2. to-50 

### 3

- 10 Apply 4 to 7 days prior to Defoliant Tank 

### High tertitily lavel 

### PREP'''' boll**op~ning**



### Mix" Rank cotton application. To be used as 

### a**se~~~~:llrealment** 

### with, nol in I of PREP:" boll

Pre-Conditioner Hot, dry, above**80~F** 213 

### 0.5 12 Apply 4 10 7 days prior to 

### to, Defoliation Cool. abOve 65'F 

### 1 113 

### 1.0 6 t5- 

### 50 

### 2·5 defoliant. Enhances top
01 crop deloliation reducing deterioration 01 bottom crop Rank cotton 

### .nd allows 101 earlier

Pretreatment With Defoliants Prior to PREpnt brand Ethephon Boll Opening Treatment: II Ihe cOllon is overly rank or laying down in the middies and good spray coverage 01 tho boUs with PREP'''' is diUicull, 

### a pretrealment with**delo~ants** will be uselulto improve boll coverage with PREP""< Use dosage rates 01 PREP"" recommonded for boll opening, Read and observe all appropriate label use directions and precautions lor Ihe delolianl used

. •• Can use up to lull label rate lor each product. 

# e·· In Catilomia and Ariz:ona use 

### a volume 01 no lessthan 

### 5 gallons per

## ~cre loraerial applicalions. Boll Maturity A boll is mature when il is too hard to be dentedwhen squeeled between thumb and fingers. 100 hard 10 

### be sliced with a sharp knile, and when the seed coal bccomoslighl brown in cotor. 

### Use Limitations

• Do not excoed a maxrmum ot 

### 2.0 lb. othopllon active ingredient por acre per year through combined or repeated uses ot ally ethephon products, Boll Opening: Do not tank mix PREP I'" brand Ethephon with 

### a desiceant if the collon is to be spindle 11arvestad.

• Pre-Condilion tor Detoliation: 00 not tank mix PREP»" brand Ethephon with dosiccants untess ptantdesiccalion is requirod. 00 not use a deloliant bolore thore is sutftcient mature unopened bolls to produce rhe desired yietd {see General tntormation section on how to test for boll maturity.

• DO NOTAPPLY PREP"'" BRAND ETHEPHON IF RAtN IS EXPECTED WITHIN 6 HOURS. Raintat! within 6 hours 01 application may reduce product perlormance. 00 not ptant another crop within 30 days alter treatment. WHEN TO HARVEST COTTON 00 not harvest cotton sooner than 7 days alter a treatment with PREpm brand Ethephon. Observe the treated crop and harvest when optimum boll opening has boen rcached. Too earty halVest might reduce the tull advantage 01 the treatment and too late a halVest may reSUlt in reduced quality and loss 01 lintwhich will drop trom the plant



# 105PREP'''' Crop Situatfon Ptnts/Acre

Directed Spray Application

Over.The-Top Applicalion 

### 11/3

t 1/3-22/3

USE LIMITATIONS 

### 50-60

40-60 

# TOBACCO (Flue-Cured

Specfffc Directions
Use drop nonles. Choose TG or OC spray fips gpa at 

### 35-40 psi and at tractor speed 2 nozzles per row; one on each side of the spray fo the leaves to be ripened om,.,,!!eiS essentiaL With a directed

### ,p!,~y,.~,!"". I only when leaves remaining on To ensure remaining leaves are mature, test plants as described undertho section "Proper I tho lower rate in a normally mature crop when experience lndicafes tl$t p1!"iq!um ripening inducement is required, Use the higher rate when fhe Crd!t"i!;'heavy and has a tendency to be more rank or when temperatures an1frao.otePIhan normal. Always test spray to determine if the tobacco is mature enoll;h to

# ,.,po,," I 10 trealment with PAEPlM Apply over.the.top PAEP"'" spray as a tine mist using three nozzles (one nozzte lips overthe centor of tho plant. and one on each side) so atlleaves are covered thoroughly, similar

### to the pallem ot systemic sucker

"

• Do not apply PREP'" brand Ethephon to immature leaves as this can result in unsatistactory coloring, weight loss and reduced leat quality.
• Do not allow the crop to over ripen in the Hold after uSing PAEPN brand Efhephon, since this may cause some reduction in yield and quality.
• Do not Ireat before anticipated maior storm which coutd preventharvest and resufl in crop loss.
• DO NOT APPLY PREPl" BRAND ETHEPHON IF RAtN IS EXPECTED WITHIN 6 HOUAS. Aainlall within 6 hours 01 application may roduce product perlormance. Do not use PAEP"" brand Efhephon with additives other than recommended on this label. Do not plant another crop within 

### 30 days after treatment
• Do nol exceed a maximum of 2.0 Ib othephon active ingredient per acre pcr year through combined or repeated uses ot any ethephon products, APPLICATION TIMING Successtul results with PAEP'''' brand Ethephon call for treatmont when leaves aro mature, not overly rank green when sprayed. To easily detennine the proper treatment timing and the number 01 leaves per stalk ready tor harvest. test spray several plants in more

• than one tocation in each field and observ,e tho response. Mafure teaves will begin to yelklw in 24 to 72 hours. Test leaves that fail fo yoUowJn 72 hours are not mature and arc not ready for PAEP"" treatment. Wait a few days to permit further natural maturing, then make another test spray or "mafurity" check, To avoid quality foss and or possible leal drop, harvest any yenowed teaves prior to application. Use tower rates under most conditions. LImit use of higher ratoe 10 cool (below 65F at tho time ottroatment) slow ripening conditions. When you have conUrmed 1he desired number ot leaves perplant that 

### will cotor, yoU can determine the number ot ncros to treat in ardor to fill the bam. Prepare your test spray by mixing one teaspoon of PAEP'" brand Etl'lOphon in 1 quart 01 water. Spray each test plant with about t oz. of this mixture, covoring all leaves with n fine mist. PREP'" will not color immature sprayed leave$. WHEN TO HARVEST AU mature, sprayed leaveswill begin to cotor within 24 to 72 hours allor PREP'" brand Elhephon applicatiOn. The yellowing process is weather dependent; cool weather will delay, while hot, sunny woather can speed up the process. Harvest treated tobacco when leaves have roached the desired color intensity.

. Harvest can commence 48 hours after PREpl', brand Ethephon app6cation. To determine harvest timing and avoid quality 1055 or leal drop, Closely monitor treated crop and weather conditions-. CURING PREpn< BRAND ETHEPHON TREATED TOBACCO Curing procedures are as much an 

### art as a scionco and each cure must be fudged on the basis of tobacco condition, interval between trealment and harvest, weather and Iype of curing tacility befote: proscription temperature and ventilation schedules can be established. To obtain maximum quality, care must be taken to observo and control the curing process closely. especially during the late ·coloring' and early**~drying·** stages of the leaf. PREP'" brand Ethephon Ireated tobacco 

### will have started the colOring process when harvested, reducing the time required in the coloring phase of CUring. Treated tobacco should be dried faster. 

### If lobacco loaves are green orcontain some groon when harvested, 

### it may 

### be necessary to color them tor a fow hours. It tho leaves are completely yellow, temperature and venflJation must be adjusted in a manner to dry the tobacco as fast as pos.sible without scalding. Once the leaf Is dried (3/4 dry), you should follow normal procedures tor curing. Since pAEp!" treated leaves cure faster, treated and unlreated leaves should not be cured fogolherjn the same bam. 

# 106

# LIMITED WARRANTY AND DISCLAIMER
The manufacturer warrants (s) thai this product conforms to tho chemical description on the label; (b) Ihallhls product is reasonably fil lor the purposes sel forth in the directions for use when II Is used In accordanco with such diroclions; and 

### (c) Ihal tho directions, warning and other statements on this label are based upon responsible experts' evaluation of reasonable tests of effectiveness, of toxicity to laboratory animals and to plants, and or 

### residues on food 

### crops and upon 

### reports 01 field experience. Tests have not beon made on all varieties orin all slates or under aU conditions. THE MANUFACTURER NEITHER MAKES NOR INTENDS, NOR DOES IT AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE. ANY OTHER WARRANTIES, EXPRESS OR IMPLIED, AND IT EXPRESSLY EXCLUDESAND DISCLAIMS ALLIMPUEDWARRANTIES OF MERCHANT·ABILITY OR FITNESS FC\A",pARTlCULAR PURPOSE. •• :. THIS WARRANTY DOES NOT EXTEND TO, AND THE BUYER SHALL BE SOLELY**RESPONSIB~!.pofiill.** ANY ANO ALL LOSS OR DAMAGEWHICH RESULTS FROM THE USE OFTHIS PRODUCT IN ANY MANNER WHICH IS

### I~COf.J~ISTENT**W~H** THE LABEL DIRECTIONS, WARNINGS OR CAUTIONS. •••••• : ••••• 

## • • BUYER'S EXCLUSIVE REMEDY AND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY !telR AN'f"'iO:,4LL CLAIMS, LOSSES. DAMAGES, OR INJURIES RESULTING FROM THE USE OR HANDliNGOFTHIS PRODUt;If:WI;IETHER OReHOT BASED IN CONTRACT, NEGLIGENCE, STRICT LIABILITY IN TORT OR OTHERWISE SHALL BE LIMITED, AT lH&IAANUFACTWRER'S OPTION, TO REPLACEMENT OF, OR THE REPAYMENT OFTHE PURCHASE PRICE FOR, THE QUANTITY OF PRODUC';WIn! RE$PECTTO WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHAll MANUFACTURER OR SELLER BE LIABLE FOR**sp~ru\o**TNOIRECT OR CONSEOUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OFTHIS PRODUCT. ••• • 

## •• NOTfCE TO BUYER •• Purchase of this produci does not confer any rights under patenls governing this product or the use thereof in countries oulside otthe United 

### States

. 

# •



# •

IDEF and Guthion are regislered trademarks 

### 01 Bayer AG, Germany. 2Dropp IS a registored trademark of AgrEvo. )HaIVadG is a registered trademark 

### 01 Uniroyal Company

.

. 1Malathion is a trademark ot American Cyanamid Company.

Rh6ne-Poulenc Ag Company P.O, Box 

### 12014,2 TW. Alexander Drive Research Triangle Park. North Carolina 

### 2n09 PREP is the trademark of Rh6ne-Poulenc. FOLEX is a registered trademark 

### 01 Rhone-Poulenc.
PREP'" brand Ethephon for Cotton and Tobacco (PENDING) Submilled 11t6/96. Resubmitted 4117197.



# 107**---~~----- ~~------------------** 



# •

• RH6NE·POULENC AG COMPANY



### EPA Correspondence No. GSPfeth/046 April )7. 1997
U,S. Environmental Prolcc!ioll Agency Office ofPesticide Programs Document Processing Desk (H7504C) Room 266A, Crystal Mall 2 1921 

## Jefferson Davis Highway Arlington, V A 22202 

### Attn: Ms. Cynthia Giles Parker(PM No. 22), •••••• 

### • 

## •• • 

## • 

## •••••• 

# • •



# .. ••••

## • 

## • • 

## •••••

RE: EPA Reg. No:-**2(}4~41&** 

## PREpn! brand Elhcllhon for COUOIl and Tubacco; Label revisions in response 10 

### yourcorre,sponticllce of 

### March 27, 1997.

Dear Ms. Giles· P:lrker. •••• 

## • •••• 

## • • • •••••• 

### • ••• • 

### • 

## •



# .. • 

# ·
.. •• •

•••• 

### ••• • 

## • •



# ..

I am 

## submittingfive copics ofadraft label witlI the**com~ttiuns** 

## which yOll 

## requested in your March 27, 1997 correspondence. I have highlighted the changes on onc ofthese 

### labels [0 

### facilitate your review.

The following changes have been made:

Hazards to Humans Secllon: Replaced lext

## wilh recommencled wording

. Statement

### ofPractical Treatment Section: Changed title to "FIRSTAID" Deleted "If

### Inhaled" Slalement 

## Ifon Skin: added: "Getl11edical :llten!ion:' IfSwallow'ed: Added ·'or 

## Pilison Cumrol Center".

Note to PhysiCian Section: Moved this section from precautionary statements ttl fIRST AID section Aclded: ·'Treat**sympl(m)~uically.** 

### Consideration Sllould be 

### given to the possibility that over Cxpos\lrc to materials orherthan**thi~** 

### producl may have occurred. No specific anticlote is available. Probable mucosal damage may contraindicate the use ofgastric lavage,"This Sliuemcnt complieswith your input and was recommended by 

### ourcorporate physician ;15 

### appropriate for all ethcphon labels. Deleted: Entire prior statemellt.

,>() [lOX 

### 1m1".zI',',' ALEXMiO!011**r,HiV~** H<'5(ARG;-i IRIMK,tE hlP;;;. H C 2:70" 21l1-1**(1tO~s--.:J":X1OO** Exceffence in Performance Pride inAchievement 

## '1'1.**"JlI4AIIO~g"** TtL!:'>: !;Wl.Rrfi**.FlS9J7H·MJ~;Wr**HEAC( !<r>::: 

### '''Of' 11HH1N.".Tion:..I_ I)I$m;8U]I(l!-1 srrWICFS 1(i F'X**tl0~\CH.n ::~'-::n:r!7-AH.S','il:f1HhY**  i·1<-, li--,;:; 

# 108

-**~-.~.----------**

# •

• PPE Section: Modified glove stalement 10 meel 

### currentrequiremenls.

Directions for 

## Use section: Moved first 

## paragraph from Agricuhnral Use Requirements box to text above box

. Use Limitations section: Modifed 

## 2.0 Ib ailA statement 

## as suggested. •

## ••••• 

## • •• • 

## • •••••• 

# • 

# • •••• 

## • •••• 

## • • • 

## •••••• 

# · If

### you have any questions concerning this matter, 

## I ClIli 

### be reached at**919-54§-2687~··.** 

## : ••••• 

## •• Sincerely.

# ~~ Gail Powell.Ph.D

. Registration Manager 

# • • 

# .... , 

# · 

# .. . , 

# . ••••



# ...• • 

# ..

109**-----------~---** .. -

# •

• •

CERTIFIED MAIL
Gail Powell PhD. Rhone-Poulenc Ag Company P.O. Box 12014, 2

# rw Alexander Drive Research Triangle Park, NC 27709
Dear Dr Powell: Subject: 

## Reregistration**~'7** 

## 1997

PREP brand Ethephon Plant Regulator For Cotton and Tobacco EPA Registration No. 264-418 Your Submissions Dated January 16 and March 13, 1996


## We cannot accept your labeling submitted for reregistration of ethephon until you submit five (5) draft labels with the following corrections. 1, 

## Update the Hazards to Humans section so it reads as follows:
Corrosive. Causes irreversible eye damage and skin burns. Hannful jf 

## swallowed or absorbed through skin, Do not get in eyes on skin or on clothing.
2. In the Statement of Practical Treatment Section you may delete the IF INHALED: 

## secllon since this product is in Toxicity Category IVfor inhalation toxicity. At the bottom of this section add:
NOTE TO PHYSICIAN' Probable mucosal damage may contraindicate the 

## use ofgastriC lavage.
3. In the IF ON SKIN statements add


## Get medical attention.
4. Delete the Note to Physician section in the Hazards to Humans section.



# 110

# I



# 1
J

..**~** 

# • 1::4

.. ...

.

### ~



# ..l .,

# •

• -2-
5. Move "Do not apply this product in a way

....agency responsible for pesticide regulations" out ofthe Agricultural Use Requirements section to immediately belowthe heading "It is a violation of Federal..

..with its labeling."
6. Modifythe Use Limitation so it is clear that the maximum that can be applied to cotton is 2.0 lb. ofethephon as active ingredient per acre from all sources of ethephon not just this product
Submit the labeling reflecting the above mention changes to the Agencyfor review 

## within fifteen (15) daysofreceipt ofthis letter. Failure to do so will result in issuance of a Notice of Intent to Suspend your product's registration.

cc: Wanda Daughtry Judy Loranger 

## Reregistration Branch Sincerely,

## ~.

# J /-



# ....; 

# , 

# .

. 

# . Cynthia Giles-Parker Product Manager (22) Fungicide-Herbicide Branch Registration Division (7505C)

Special Review and Reregistration Division (7508W)



# 113

._. -- 

## --------------------------

# PREp TM

# brand Ethephon FOR COTTON AND TOBACCO For Commercial Use 

## Or Agricultural Use Only. Not For Residential Use .ACTIVE INGREDIENT: Ethephon (2-Chloroelhyl) phosphonk: ac;d'

........................................................55.4% INERT INGREDIENTS: ..............................•.....•........•.............................................................................44.6% "This product 

### contaIns 6 pounds elhephon pergallon. 

## EPA Reg. No. 264·418 EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si uSled no 

### onliGnda fa Gllqueta, busquo a algulon paraquo $0

### la oxpUquo a ustod on detallo. (It

### you do not undQrstand the label, find 

### somoone 10 oll:pfain it

### to you in dotaiL)



## • -"Fiiorr**iMiiE[i02jlltC;1AiiL;:1A"niddl:r[RBAA]N[iS[jP~D:l:Bii:TIAAjT'iilol2ilN:EEnmii.;;-rgiji.;;ni(c;j:I**

## ....**i1Oi.iN~Li:Y~CSCiiiliiI12i44-HHGOuiir;;.iAAr:DO';.y~lN.8BiDf).x;::33:3j;4-i=7715517'77;-­** For PRODUCT 

## 1l.S.E. Information Call**1~800~334-9745** Tho use of thIs product for a varioty of plant growth regulation usas aro protected 

### by United Stalos and foreign patenls including U.S. Palent 4,240,819. No ricon$(J is granted to use this product In counlr!es olho( than the United Stales or for any use not contemplat&d by this laboL liabilityfor patent Infringement may result from use orsale 

### ofthis product outside the United**States.~** 

# STATEMENT OF PRACTICAL TREATMENT IF IN EYES: Hold eyelids opon and flush with 

### a gentle stroam 01**wat~r** for at least 

### 15 mInutes. Get medical attention, preferably an ophthalmologist. IF ON SKIN: Immediately wash skin with plenty of soap and water. 

# (')-e\y , I IF 

### SWAUOWED: Do not induce vomiting. Promptly drinka large quantity of milk. egg whiles, gelatin solUlion or 

### ifthese are not available, drink large quantitios ofwater. Avoid alcohol. Call a physician imm&diatoly. IF INHALED: Remove victim to fresh air. 

### If not breathing, giva artificial respfradon. Administer oxygen if n&CGsssry. Get medical atlention. 

# PRECAUTIONARY STATEMENTS

• DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS CORROSIVE. Causes IIyG and

### skin damag&.

### ~

### befatal 

### if absorbed through skin. Harmful 

### if swallowed or inhalod. Avoid breathing 

### spray mist 00 not get

### in eyos, onskin oron 

### clothing. Koep awayfrom domestic animals. 

## Nore TO PHYSICfAN There is no specific antidote. All trealment shook! be based on observod signs and symptoms ofdistress in tho patient. Overexposure to malorlals other than this**prod~ .baw:,,~ned,**  Victims 

### of sever.**overexposure'~o1nhal8fioJ't..,~ould** 

### be kept undor modical observation for 

### up to 72 hours for delayed onset 01**~** pulmonary edema. In s victim of**'tNGr~·G~poslfflj** 

### by ingestion, carelul 9islrk: lavage is required dUG to tho possibiffty 01 stomach or osophagoat pMioration. this matenal Is an acid, but use of alkaline subsTances 

### to neutralize it 

### is contraindicated,**~** 

# ... • •

•••• PERSONAL PROTECTIVE EQUIPMENT (PPE) • 

## • Applicators and othor handlers must wear coveralls: ovor sllort-skloved shirts and short pants, waterproof**glotal"~omicaf.rQsistant** lootwear plus socks, protoctivG oy.wear, chomical·resistant headgoar for ovorhead exposuro**1ll~.c;Qemical.re~stant** apron when cleaning equipment or mbdng and bading. : .: ••• Discard Clothing and' othor absorbent materials 

### that have been dronched or heavily contamlnatedv41;.Ibis proZlul:t.s.&lncentrato. 00 not reuse thom. Fotiow manulacluror's instructions for cleaning/maintaining PPE. 

### If no such instrt.Jctl:V'\:fiorwasbablo" usa dotergont and hot water. KOGP andwash PPE separaloly lrom other laundry. ••••• • ••••: When handlSfs use closed systems, enclosed cabs, or aircraft in a mannorthat moets Iho requirelll861,a.I!'Sled in th90Workor Protection Siandard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-S)), the handlor PPE requirements may be:**~U&Jd** or 

### modified as 

### spoo!ied in tho WPS. • .:•••



# .... 

# ·
..

•• • 

# 114

# • User Safely Recommendallons Users shoUld wash hands OOloro ealing. drinking. chawfng gum, using tobacco 

### or using the toRot. Users should remove clothing immodiately ifpesticide gets insido. Thon wash body 

### thoroughly and put on clean clothing. Users should remove PPE immodiatofy after handflng this product. As $000 

### as. possible, wash thoroughly and 

### chang. Into cloan 

### clothing. Wash tho outside ofglova, befor. 

### removing. 

## ENVIRONMENTAL HAZARDS 00not apply

### dirodly to water, Of'to areas 

### whore surface water is prosent orto Intortldal aroas below tho moan high**wat~r** 

### mark., 

### Do not contaminate watorwhen disposing of equipmentwashwaters. 00

### not contaminalo wafer used lor Irrigation or domostic purposos. 

## SPRAY DRIFT Avoid spray drift. 00 nol apply 

### whon woathorconditions may cause drih. 00 not allow

### this product

### to drift on 10 non-Iargot

### areo. Drift may result 

### In illegal residuas or Injury to adjacent crops and vogotalion, in tho form of 

### loaf yellowing and detoHation. To avoid spray drift. DO NOTapply 

### aerialty when wind 

### speed is greaterthan fO mph orduring periods 01 temperatura Inversions. Use 01 largerdroplel size

## win aJso reduce spray drift. AVOIDING 

### SPRAY DRIFTATniEAPPUCATIQN 

### SITE IS 

### THE RESPQNSIBIUTY 

### OFTIiEAPPLICATOR 

### Tho interaction 

### of many equlpment·and-woalher-rel8ted lactors determine tha potential for spray drift. Tha applicator is rosponsiblo lor considoring all theso lactors when making docislons. Tho following drift managoment roquiremonts must be followed to avoid olf·target movomentlrom aerial applications to agriculturallield 

### crops. Those requirements do not apply to lorestry applications, public health uses or to applications using dry lormulations. 1. 

### The distance 01 the outor mosl nozzles on tho boom must not oxcoed 314 

### the looQth 01 the wingspan or rotor. 

### 2. Nozzlas must always point backward paralJoI with the airstream and navor be pointod downwards more than 

### 45 <.!ogrees. Where slates have more stringent regulations, they should beobserved. Tha 

### applicatorshould bolamUmrwith and take into tiC(:OOnt the 

### Information covered in the Aerial Drift Roduction Advisory 

### below: 

## AERIAL DRIFT REDUCTION ADVISORY {This section Is advisory in nature and 

### does 

### not supers&de the mandatory label requirements}. INFOAMAnON ON DROPLET SIZE The mosl affective way to reduco drift potential is 10 

### apply !arge droplets. The best drift management stratogy is 10 apply Ihe largest droplets that provide sufficlont coverage and controL Applying larger droplets roduces drift potential, but will not prevent drift 

## n applications aro modo improperly. or under unlavorable environmentai conditions (Sea Wind, Temperature and**Humid~y.** 

### and Temperature Invorsions). CONTROLUNG DROPLET 

### SIZE Volume· Use high tlow rato nonlos to apply the highost practical spray volumo. Nozzles with higher rated llows produce larger droplets.

. 

# e Pressure·

### Do not excooo the noule manulacturer's rocommondod preSsures. For many nozzle typos Iowor pressuro producos largor dropklts, When higher llow ratos are neoded. 

### use higher llow rate 

### nozzJos instead 

### of increasing pressure. Number01 nozzles

- Use the minimum numborof nozzlas that provide uniform roverage. Nozzle Orientation· Orlentlng nozzles 

### so that the spray is relaased parallel to the airstroam producas larger drop/ets than olher orientations and 

### is the rocommendod practico. Signilicant dellection lrom horizontal wili 

### reduce droplet size and increase drift potential. Nozzle Typo· Usa a nozzle typo thaI is designod lor the inlended application. With most nozzle typos, narrower spray anglos produco larger droplets. Consider using low·(hift nozzles. Solid stream nozzles orientod straight back produca tho largesl droplets and the Iowost drift. BOOM 

### LENGTH 

## •••• 

## • • For some usa patterns, reducing the effective boom length to loss than 3/4 

### 01 the wingspan or rotor length

### 'lIarl~rther reducs drifl 

### without reducing swath wklth. • ••••• 

## • APPLICATION HEIGHT •••••• • Applications should not be made at a height greater than to leet above the lOp 01 the target plan. unloH a grtllterth.eight is requirod for ai{C1'attswety. Making applications at Ihe lowest heightlhal is 

### sa!e reduces exposure 01**dropl9t.~~aporaUonoand** 

### wind. SWATH ADJUSTMENT •• • •• :


# ...,.. 

# .... When applicalioos are made wUh acrosswind, Ihe swath wlH bo displaced downwind. Therelore, on me up and dowJlwind odges 

### of Ihe llokl, the applicatorshould compensate for this displacement by adjusting the path 01 the aircraft upwind. Swalh aO!uslment distance should incroasa, with Increasing drift 

### potential (highor

### wind, smallor drops, Gte.). : ••• 

## ••••



# .... • 

# ••



# .. 

# .

115

### po"""'i!',1 is lowest betwoon wind spoeds of 2 • 10 mph. However. man), lactors, including droplot sizo and equipment typo 

### dotormine drift potentia! at any giyon 

### spood. Application should bo avoklod be-low 2 mph duo to variable wind direction and high inversion potentlal NOTE: Local I.train can influooco 

### wind patterns. Evory appticator should 

### befamiliar with local wind panarna. and how 

### they aHOd spray drift TEMPERATURE AND HUMIDITY Whon making applications 

### In low telativo humidity, sot up oqufpmont to produce largot droplets 

### to compensato for evaporation. Droplet ovaporation 1$ 

### most SOvoro when condhions are both 

### hot and dry. TEMPERATURE INVERSIONS Applications should notoccur during a !ompet8ture inversion bocauso drift potentia! is high. Tomperaturo invorsions restrict vertical ail 

### m1xlng. which causes small suspended droplots to romain in aoonconlrated cloud. This cloud can movo in unpredictable direclions due 10 tho light variable winds common during inversions. Temperature invorsions arOo characterized 

### by Incruasing temperatures with attitude 

### and are common on night$. with limited 

### cloud cover and light to 

### no wind. They begin to form as the SUn sots 

### and oflsnconllnuo into the morning. Tholrpresonce can be Indicated 

### by groundfog; however, 

### iffog 

### is nol prosent, inversions

### can also be idenlified 

### by tho movement of smoke from 

### a ground source Of an aircraft smoke genarator. Smoke that layers and ITlOV$S laterally In 

### a concentrated 

### cloud (undor 

### low wind**cond~ions)** Indicatos 

### an inversion, while smoko that**mov~s** upward and rapidly dissipates indicates 

### good verticat 

### air mixing. 

### SENSITIVE AREAS The pesticide should only be applied when thlt potontial for drift to adjacent sensitive areas (e.g. residential arltas, bodies 

### of wator, 

### known habital for threatened or endangorod species, non-target crops) is minimal (o.g. when wind 

### is blowing away lrom the sensitivo areas). 

# e USE PRECAUTIONS Do not apply PREpn.t brand Ethophon lorCotton and Tobacco through any typo 

### of Irrigation system. 

### Avoid spray drift to nearby crops ll$this product will causo modifications in plant growth. Plant injury or roduood yiGlds will rosult. 

### Mix only the amount of spray you expect

### to uso Oooch day. 

### 00 not allow mixod SQ!Lrtlon to stand ovornlght. 

# DIRECTIONS FOR USE**~.** 

### It

# -i..- a violation of Foderal law to us. this product In 

### a mann.r Inconslstont with /**~** Read entlr. latwll before using this product. 

### Its tab.llng.



# , =--------,

00 not appty this producttn 

### a way that will contact workors or othor porsons, either directly or Ihrough drift. Only

### prot"oct:"~:':~;'~I~,~:

# I

be In tho area during application. For any requlremonts specitlc to 

### your Stato or Trlbe, consutt thlt agency tE 

# I p'''-tlddo rogulations.
only rn accordance with 

### its taooting 

### and with thlt Worker

# P~O~'~ect~]io~n~St~at:n~d~'~'d~'~4~O~C~F~R~P'~rt~'**7~:O:;'~j~~2~~si~**

# I for the protection of agricultural workers on farms, forosts, nursories, and and It contain! roquiraments for training. d&eantamlnatian, nQtilicaiion. and 

### and exceptions pqrtaining to the ,statements on this label**~about** i roatricted-Gntry intervals. The requirements In this 

### box only uses product Standard. notonteror 

### allow workor entry Into troated arens dutlng the rostricted-entry intervalJREI) 01 48 hours. Tho REI 

### Is 72 hours in areas 

# wh.", ""'"'!10 rainfall is less than 25 Inchos poryoar. PPE 

### roquirad for early 

### entry to treat&d areas that 

### Is permitted under the Workar Protection Standard and that involves contact with anything that has boon troated such as plants. soil or**~ater** 

### is coveralls over Iong-sloeved shirt and long pants, chomical resistant gloves such as any waterproof gloves, chomical fOsistant footwear plus socks, and protGctive ayowoar. For overhead oxposuro. chemlcal..fO$istant hoadgear 

### Is also required. 

## r

•••••• • •• • 

# • •••••• 

# • • ••••• • • 

# .....

# . •



# .. . ., 

# . ·
.. •• 

## •• ••••

## • • • 

## ••••• 

# ·
., •• 

## •

## • • 

# ·
.. .' 

# . •••

## • •••• • ••



# .. 

# .

116

# • . 

# , STORAGE AND DISPOSAL STORAGE Do 

### not contamlnato waler, food, 

### orfoed by 

### storaoe ordJsposal. If 

### container is broken orcontants have spilled. follow all precautions Indicated above and 

### clean up 

### immedIately. 

### Sofa!. cloaning up. 

### put on full length trousers, long sleaved shIrt, protodivo gloves. and gogglo$ Of 

### face shield. 

### Soak up spill with absorbent media such as sand, Garth orothersukablo malerial and dlsposo ofwas10 at an approved waato disposal facility. 

### PESTICIDE DISPOSAL Pesticide waJlO. ato acutely hazardous. Improperdisposal of excess posticide. spray mixture, orrinsato is 

### a violation of Fodoral law. 

# nthase wastes cannot be dispo&ed 01 by UaG according to label Instructions, contact your Stat. Po.ticido or Environmental Control Agoncy Of

### tho Hazardous Wast. representatNc at the noarest EPA Regional 

### Ofllco 

### lot guidance. 

### CONTAINER DISPOSAL Triple rinse 

### (Ot oquivalont) tho empty conta.inors. Thon offer for 

### tqcycling Of foconditioning, or puncture and di&po$O 

### of In a sanitary landfl/f, 

### Ofby 

### IncIneration or if alklwod by state and 

### local authorities, by 

### burning. 

### II container Is burned, stay out 01 smoke. RETURNABLE

-- REfiLLABLE CONTAINERS Mer UN, 

### return the conlalnerto tho point of 

### purchase Ordesignated locations. 

### This- oontalnor must only be 

### relHled**w~h** 

### PREpm brand Elhephon for Cotton and Tobacco. DO 

### NOT REUSE THE CONTAINER FOA ANY OTHER PURPOSE, Prior to refUlIng. Inspect thoroughly fOr damage such as 

### cracks, punctures, abrasions and 

### damaged or worn 

### out threads on closure devices. Do 

### not rolill or transport damaged or loaklng containers. Check for leaks atter relilling and boforo transportation. If 

### tho container Is not 

### boiog refilled, return 

### it to

### tho point of purchase

. 

## GENERAL INFORMATION COTTON Aloliarspfay of PREPN brand 

### Ethophon for Cotton and Tobaooo will 

### accolerate opening 01 

### mature unopened cotton bolls 

### and enhance defoliation which can 

### result in oarlior harvest with an irn;:feasod recoyerable yield. PREpnt treatment on cotton allows Increased efficiency from 

### a once-over harvost. TOBACCO (FLUE-CURED): A foliar spray of 

### PREP'noI brand Ethephon promotes early, uniform "yellowing· 01 mature tobacCo. PREPD' r&duces curing time, allowing 

### mora efficient use of

### curing barn 

### space, and 

### incr06$od control OYer harvest schedulos(L--/ SPRAY PREPARATION Add 

### 112 to 

### 314 of the roquirod amount ofwaterto the 

### spray tank.. Start agitation. Add the t&quirod amount of PREPnc brand Ethephon. and tho romaining amount 

### ofwater. Prepare only as much spray solutIon as can 

## txt used on the day of mixing. Do not allow spray solution to stand 

### oYernight. 

### 00 not 

### spJlJ the concentrated product on spray equipment, or any airplane parts. 

### ANYSPillSSHOULD BE RINSED IMMEDIATELYWITH PLENlYOFWATER. Use of

### a nursa tank is 

### highly recommended for avoiding possible spills 01 

### concentrated formulation on spray equipment orany airplane parts. TANK MIXTURES WITH DEFOLIANTS 

### AND INSECTICIDES**~** 

### PREpnt bmnd Ethophon is 

### compatiblo with DEFI, FOLEX-, DroW, Harvade3

, 

### Methyl Parathion, Guthion 1

, 

### and Malathion4• 

### PREpN

..., may 

### be applied in s-oquenco or as 

### a tank mixture (DO 

### NOT TANK MIX -WIlli DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Followall applicab1e us.procautiollS and rate peracto recommendations on labels ofproducts applied 

### as tank mixtures or In soquanco**w~h** 

### PREP 1M

### brand Ethophon. In some cases slight reduction in 

### boH opening respons. has boen observed when tank mixes with defoliants wore usod. 

### Good agitation in tho sPfay tank Is assential and a 

### tank mixture should not be allowed 

### to stand**w~hout** 

### agitation for more than 510 10 

### minutes. Read and ob$arve all appropriate label usedirections and precautions for the defoUants and insecticldos used, 

### NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREprw BRAND ETHEPHON WITH DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN 

### THE FORMATION OF HYPOCHLOROUS ACIDS 

### WHICH ON 

### HEATING WILL EMIT TOXIC CHLORIDE FUMES. DO NOTMiX**PREP~** 

### BRAND ETHEPHON WITI-I AMMONIUM THIOSULFATE. SUCH TANKMlxruAES MAY**~".IN** 

### FORMATON OFTOXIC FUMES. •••• EQUIPMENT CLEANING 

## • • •••••• • Because of 

### the acidic nature of thls product, proionged exposure to spray deposit will damagl\**~ip** 

### plastics, ptrtain paints, and motals. : .: ••• Rinse thoroughly with adotergent and water all exposed acrylic plastic·typo materials (e.g.,**aircratt.w1odchiold~,**

# a.- ·painlad surfaces wlthln an hour altar oxposure to spray deposits. • ••• •• 

## • •• At 

## ttt. and of each day, rinse thoroughly with a detorgont and wator aU the motal pans of tl'lv.fretaft and"ttJo·:tssociatod spray equipment exposed 

### to tho spray**dopos~s.** 

### ••••• • 

## • •• •• •

•••• •••• • •

••



# 117

# • .....-- - 

## -----------

EXPECTED PREpm 

## ONE SPRAY VOLUME APPLICATION USE 

### CONDITIONS RATE 

### GALLON 

### (Gal./A) TIMING 

### PREpm TREATS 

### Plnt.fA LBS A.1. 

### Acres Ground Air·" PREpl'N 

### Hot and 

### dry WF

### or 1113 

### 1.0 6 Apply 

### when tho numbor 01 

### Boll 

### Opon.r· hlghor 

### majuro unopened bolls Is Dfy

### and 

### 75

### to**8O~F** 

### 2 1.5 

# • 15·50 

### 2·5 sufficIent to produce tho desired crop. 588 bebw 

### lor Cool 

### but above SS&F 

### 2213 2.0 3 lost 

### of boll 

### maturity. Treatment uniformly opens 0' 

### boUs 710 14 

### days oarHor. Aank cotton 

### PREtm' 

### + High soil moisture 

### 113 0.25 

### 2. 15·50 5·10 Apply 

### 4 

### to 7 days prior to 

## FOLEX" 

# '" PREpnf boll 

### opening 

### Dafoll.nt Tank 

### High fertility 161/01 application. To 

### be used as



### MIx·· 0' 

### a sGquonliaJlrealmonl wijh. 

### not In 

### place 01 PAEf>ni boll Rank cotton 

## Iooooio-o ttoalmen!. PREpTM+ Dropp High**so~** 

### moiS1uro 113 

### 0.25 

### 24 

# to ·50 3·10 Apply 4 

### to 7 days prior to 

### O.follant Tank 

### High fortmty 

### lovol PREpm boll 

### oponing



### Mix·· Rank cotion 

### application. To 

### be used as 

### a soquentialtrea1mont with, not in 

### place of PAEpni boll**oponir:!·~treatmGnt.** 

### Pr.·Condltloner 

### Hot, dry, abovo 80e

### F 

### 213 0.5 12 Apply 

### 4 to 

### 7 days prior to 

### fo, D.follatlon Cool, 

### above 

### 65"F 1113 

### 1.0 6 t5·5O 

### 2·5 defollan1. Enhancos top 

# "' crop defoliation reducing deterioration of bottom crop Rank cotton and 

### allows 

### fo, e.rlior harves!. 

### ·Pretreatment With Defoliants Pnor to PREpN brand Ethephon SoU Opening Treatment Ifthe cotlon 

### is ovorly rank or 

### laying down in tho mlddlea and 

### good spray coverage 01 

### tho 

### bons with PREPnI is difficUlt, 

### a pretreatment 

### with dofollants 

### wilt be 

### usofulto imptolle

### boltcovorago 

### with PREPlW, 

### Us.dosago ndes of PREpm recommended lorboll opening. Road and observe all appropriato label us& directions and procautions for tho dalolilU'Jt used. "Can usa up 

### to fuillabol rato for oach 

### product.

•

...In California and Arizona: 

### use a 

### volumo 01 no 

### loss than 5 gallons por acto lor aerIal applications. 

# e Bott Maturity 

# ;/ ! -"J

Aboll 

### is mature when 

### it is too hard to 

### be domedwhen squOGzod OOtwoon thumb and fingors. too hard to bo sliced with 

### a sharp- knit., 

### and when tha 

### soad coat becomes light brown in color. 

### Use Limitations '. 

# , 00not excoed 

### a maximum 012.0 lb. ai/A

### forcomblned uSO$,of PREPN brand Ethophon par acre 

### poryoar_ Boll Opening: Do 

### not tank 

### mix PREP'M bland Ethephon with a"

# aos-icC1ii1tit tho cotton is 

### to bo spincile harvested, Pro--Col'Idition lor Dololiation: 

### Do not tank mix: PREpN brand 

### Ethephon with desIccants unless plant desiccation is required. 

### Do not uso a 

### dololiant bofore thoro is 

### sufficiont mature unoponed bolls to produco tha desired yield (sea Ganorallnlormation soclion on how to tost for boll maturity. •••• DO 

### NOTAPPLY PRE?N BRAND 

### ETHEPHQN IF RAIN 

### IS EXPECTED WITHIN 6 

### HOURS, Rainlall within 6

## ~ON'df·application may roduc. product porlormanco. :

...:. 

### Do not plam anOlhorcrop within 30days aftortroatman!. • 

## •••••• • WHEN TO 

### HARVEST COTTON • .: 

## •• • • • Do not hjlMstcotton soonerthan 

### 7days aftor

### a treatmont with PREpTSI brand EthGphon. ..:•• :... Observe tho 

### traatod crop and 

### harvostwhon optimum boll opGning has been ranchO<:!. Too oarly harvosflfllght rodJce.th1t full advantage oftho trorumont and too lato a harvost may result in rGduced quality and loss of

### Nntwhich will drop f"""1

# m" piant. •• •• 

## •• ••• • 

# · 

# .. • •



# ...- •••• • 

## ••



# .. .

118

# TOBACCO (Flue-Cured Only) PREpOI Crop Situation Plnta/Acr.
Diroctoci Spray t 113 

### Application**OVor~Th.·Top** t 

### tl3-2213 Application Spray Vatume Gattonsl



## Acr. 50·60

40-60 Speclftc Directions
Use drop nozzles. Choose TG 

### or OC 

### spray tips d&slgnod to apply SO • 60 

### gpa at 

### 35-40 psi and at tractor speed of 

### 2-3 mph. Use 

### 2 nozzl&s per row; ooe on each !lido oftho row droppod 

### low enough to direct tho spray 

### to tho 

### I.avos to be 

### tiponod and harvested. Thorough spray covorage is 

### osaent)a1. WIth 

### a directed spray, 

### be sure to 

### harv05t allle8ves with 20% Of I'l'10(8

### yellowino. Treat only when I.aves remaining on th. stalk are matur.. To ensure remaining leaves are matura, test spray soveral tobacco plants as doscribod undertho section -ProperTlmo ofTreatment· Use th. lower rata in a normally maturo 

### cropwhon exporionc. jndicates that minimum ripening inducement is roquiroo. Us.the highor rat. when the crop is 

### heavy and has a tendency to 

### 00 more rank or whon temperatures are IoWar than normal. Always t.&t spray to detormine 

## n the tobacco is mature .nough to respond to treatment wkh PREpm Apply 

### over-the-top PAEprw spray as a fine mist using throo noules (ono nozzlo 

### tips 

### ovortho contor of tho plont, and one on oach side) so all loaves

•**ar~** 

### cov.rod thoroughly, slmifarto 

### the application pattern 

### 01 systemicsucker 

### L.

__________

## -Lc-

________-"L.

__________**~oo~nl~rn~"~ao~"~nl~'~,~U~,~'~.~'~m** 

## ••**~v"o~"~'~'~~rn~o~14~O~I~o~6~O~o'.~L"_**

## ____________ _J 

### USE LIMITATIONS Do not 

### apply PREp1lI: bfand Ethephon 

### to immature leav.s as thls can rosult in unsatistactory coloring, weight loss 

### and roducod loaf quality. Do 

### not allow tho crop to 

### over ripon in tho field altor using PREpl'W bfand Ethephon, since this may causo soma r&duC1ion ln yiold and quality, 00 oat

### treat bolore anticipated majorstorm which could provent harvest and result in crop loss. 

### • DO NOTAPPlY PREflTW BRAND ETHEPHON tF RAIN IS EXPECTED WITHIN 6 HOURS. Rainfall wilhm Ghours 01 appIlcat!on may reduce product porformance. 

### 00 not 

### use PRfP!W brand 

### Ethophon with additiv9$ otherthan rocommendod on this labol. 

### Do 

### not plant anothercrop within 

### 30days aftertroatment. ,/. 00 not

### eXCHd 21bs ethophon PM acre poryoar. APPLICATION 

### TIMING Successful results with PREPlW brand Ethephon call fot 

### treatment when leave. are maturo, not overly rank green when sprayed. To easily detormlne the propertroatmant timing aM the numborat leavos per stalk ready lor harvest. tost spray several plants in 1TIOf8 

### than one location in each ffold and observe the response. Maturo !Gaves wBI begin to yellow In 24 

### 10 72 hours. Testl.avos that tail to yellow in 

### 72 hours are not 

### matoro and are IiOt roady for PREpru. treatment. Wait a tow days 

### 10 permit turthor naturol maturing, then

• make anolhartG&t spray or ·maturity" chock. 

### To avoid quanly 106$ and or possible Ioat drop, harvest any yellowed

## 1~a:v8S priorto appHcation. Uselowor ratos under most conditiomt. 

### Umit usa of 

### highot ratos to cool 

### (bolow 

### 6SF at the time of

### treatment) slow ripening condilions. When you have: contirmad tho desired numborat loaves 

### por plant that wHt color, you can determine tho numberofacros to 

### treat in 

### ardor 

### 10 1111 tho bam.**Prepar~** 

### yourtest spray by 

### mixing one toaspoon at PREPno: brand Ethophon in 1 quart atwater. Spray oach test plant with about 1 Ol. 

### at this mixture, covering alileavoswith atlne mist. PREp-m wlll not color immature sprayod leavas. WHEN TO HARVEST All mature, sprayed leavos will bog!n 

### to colorwithin 24 to 

### 72 hours after PREpm brand Ethophon application. The yellowing process is weatherdependent; coot weatherwill dalay, whllo hot, sunnyweather can spe&d 

### up tho process. Hruvest traated tobacco when leaves have reached the desired color intensity. • ••••• Hruv8$t can commonce 4B hours aftor PREPTW brand Ethephon application. To dotermine harvesttiming and avcfK'l·qtality loss or leal drop. closo/y monitortroatod crop and weathor conditions. :._.:. CURING PREpN BRAND ETHEPHON TREATED TOBACCO • Curing procedures are as much an art 

### as ascienco and each curo must be

### judgod on the basis ofloSac&" conditio';. interval botweon treatmom and harvest, weather and type of curing tacility belore prescription temperaturo lind v4ntllatkSJ1..s.dh&dulos can be established. To obtain maximum quality, care must be 

### takon to 

### observe and controt tho curing preet4ltlosolf,**.s~ally** 

### during the lat.·colorlng- and oarly -drying- stagos at the loaf," •• •• • : PREpnI brand Ethephon troatod tobacco will have started tho coloring process whon harvast&<f.UMQing tho'Jma·roquirod 

### in tho coloring phaso 01 curing. Tr&atod 

## tobacco should be 

### dried tastor. Iftobacco loaves are grean or

### cOftMrfsomo**gr.o~**

### whon harvosted, 

### if: may bo nooosslll'f

### to colorthom tor a lew hours. II tho leavos aro complotoly yollow. tomperature and**vontilat~n** 

### ¢t19J be adjusted 

### in a mannorto dry tho tobacco as tM! as posslblo without scaJding. Onco tho Ioat is driod (314 

### dry), you should follo'h"Mrmai proceduros for curing. Sine. PREPTlItreatod loaves cure fastor, troated and untroatGd loansshould not

### becured togethor illHwts-tme barn

. 

# .. 

# .

119

# • .. LIMITED WARRANTY AND DISCLAIMER The manufactuuN' warrants (8) that this 

### product conforms 

### to tho cll&mica.l dDscriptlon on 

### tho labol; (h) that

### thit product 

### it roaaonably 

### fit for tho purpo

... 

### sot forth 

### In tho 

### directions for usa when 

### It Is usod in acoordance with such dlrec::tlon.; and (c) that

### tho dlr.aions. 

### warning and other statemGnts on this !abol are based upon responsible exports' evaluation 

### of reasonable !oslt of effactlVfflO$S, of 

### IOxlclty

### to laboratofy anlmala and 

### to 

### plants, and of retldues on

### food cropo and 

### upon reports 

### offield experience. 

### Testa have 

### not baon made on 

### aft varieties 

### or In alstat••orunder aU 

### conditlooo. THE MANUFACTURER NEITHER MAKES NOR INTENDS. NOR DOES IT AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE, ANY OruER WARRANTIES, EXPRESS OR IMPLIED. AND IT EXPRESSLYEXCLUDES AND DISClAIMS ALL IMPLIED WARRANTIES OF MERCHANT·ABILITYOA FITNESS FOAA PAATlCULAA PURPOSE. THIS WARRANTY DOES NOT EXTEND TO. AND THE BUYER SHALL BE SOLELYAESPONSIBLE FOA. ANY AND ALl LOSS OA DAMAGE WHICH RESULTS FROM THE USE OF THIS PRODUCT IN ANY MANNER WHICH IS INCONSISTENTWITH THE LABEL DIRECTIONS, WARNINGS ORCAl1J1ONS. BUYERS EXCLUSIVE REMEDYAND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY FOR ANY AND ALL CLAIMS, LOSSES, DAMAGES, OR INJURIES RESULTING FROMTHE USEOA HANDLINGOFTHIS PRODUCT. WHETHERORNOTBASEO IN CONTRACT, NEGLIGENCE. STRICT UABILITY IN TORTOR OTHERWISE SHALlBE LIMITED, ATTHE MANUFACTUAEFrS OPTION, TO REPlACEMENTOF. ORTHE REPAYMENT OF THE PURCHASE PRICE FOR. THE OUANTITYOF PROOUCTWITH RESPECTTO WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHALL MANUFACTURER OR SELLER BE LIABLE FOR SPECIAl, INDIRECTOR CONSEQUENTIAl DAMAGES RESULTING FROMTHE USEOR HANDLINGOF THIS PRODUCT. 

### NonCE TO BUYER Purchasa 

### ofthis 

### product 

### do4t: notoonlGr any rights under palonts governing this product or

### tho us. thoroof 

### in countries outsida 

### oftho 

### Unitsd Statoa•



### 'OEFand 

### Guthion are regislarad 

### IratI.marks ofBayerAG, Germany. 2Oropp is II

### registeredtrademarkof 

### NOR-AM Chomical Company. 3Harvadeis a reglatarod trademark of Uniroyal 

### Company. 

### "Malathion Is atradomark ofAmerican Cyanamid Company.

Rh6ne-Poul&nc

## hJ Company 

### P.O. Box 

### 12014. 2T.W. Alexander 

### Drive Research Triangle Park, 

### North Carolina 

### 2n09 

### PREP Is thetrademarkof

### RhOo.--Poulonc. FOlEX Is a registered trademark

### of RMne.floulorn:

. PREPN brand Ethophonfor Cotton and Tobacco (PENDING) Submitted 1116196. 

# ...... 

# . .. ....• 

# ·

...... ·

• • •••



# .....

# . . .

.....

• • 

# ..... •• • 

# ·
..• 

# ·
..

•••• 

# ·

.. .'



# .



# ....

.... 

# ·

.. 120

# /

# -------------------

---

DP BARCODE, 0233645 CASE, 003396 SUBMISSION, S499337 DATA PACKAGE RECORD BEAN SHEET DATE, 02/21/97 page 1 

### of 1 

## * 

## * * CASE/SUBMISSION INFORMATION * 

## * *
REGISTRATION ACTION: 674 8 MNTH RESP-PROD SPC DATA 

## CASE TYPE, RANKING 

## CHEMICALS, 

# o POINTS () 099801 Ethephon 

## 55.4000\ 10#, 000264-00418 PREP PLANT REGULATOR FOR COTTON COMPANY, 000264 RHONE-POULENC AG**cor~pjUn** 

## PRODUCT MANAGER, 22 CYNTHIA GILES-PARKER 703-305-5540 ROOM, CM2 229 PM**TE!>l~** 

## REVIEWER, ,IANDA RUFFIN DAUGHTRY 703-308-8171 ROOM, CSI lK4 

## RECEIVED DATE, 01/23/96 DUE OUT DATE, 07/21/96 

## * * 

# * DATA PACKAGE INFORMATION * * 

## *
DP BARCODE, 233645 EXPEDITE, 

## N DATE SEWf, 02/21/97 DATE RET., ! 

## &;HBMICAL: 099801 Ethephon**~p** 

### TYPE: 001 Submission Related Data Package CSF: Y LABEL: Y 

## ASSIGNED TO

DIV , RD BRAN, FHB SECT, PMT-22 REVR , CONTR, DATE IN DATE OUT 

## / / I ( ! I 

## / / 

# / ADMIN DUE NEGOT

PROJ DATE, OS/22/97 DATE, / / DATE, 

# !!

DP BC 226708 226709 

## .I / / / I I 

## / / 

# / / 

# * * * DATA REVIEW INSTRUCTIONS 

## * * *


### This product is recommended for reregistration upon your 

## final revie
... ; of label for compliance with Ethephon RED. After label review, please close this data package submission as well as the 674 submission with a reregistration decision and file all correspondence in the product jacket. Thanks

correspondence/administrative product chemistry/acute tox reviews



## .- * * DJ:3A PACKAGE EVALUATION 

# * * .- No evaluation is ' . ;ritten for this data package 

# * .., ..- ADDITIONAL DATA PACKAGES FOR THIS SUBMISSION 

### *' 

# * *
BRANCH/SECTION RSB/PCRS RSB/PRS DATE OUT 05/31/96 05/31/96 DUE 

## BACK 08/29/96 08/29/96 INS Y 

### Y 

## CSF Y 

### Y



# 121 I

LABEL Y Y

# •



# •

• DATE OUTI

SDBJBC'l" BP [X] 

## liP [J 

## PRODUC'l' CBBIII8TRY RBVIXW

TO.



## PROII.

TlIRU: 

## DP BARCODB HO.I226708 RBG./pile Syabol Ho., 264-418 IIBGI8TllATrOB [ ] RBRBGl:8TIIA'I'IOII [X] 

## RBRBG CABB BO.0382 

## PRODUCT &JIB: Prep 

## Plant RegUlator 

## lor Cotton, 55.4t AI 

## COllPUY.Rhone-PllUlenc Ag 

## COIl!!1IDY: IIBCBIVBD 

## DAH. 

## 01123/96 BRID 

## B08.439205-04 22 Cynthia Giles-Parker/Wanda Fungicide-Herbicide Branch Registration Division (7505C) 

## Ruffin Daughtry



# r J

# -'~? 

# r;;,!L- sami Malak, Chemist, 

## 11/12/96 (308-8392)

## ~7- ',iY , 

## Product Chemistry Review Section 

# u//J,{

# I'" Registration Support Branch/RD (7505W) 

## t 

# (;..U",L.-'· !,IL A 

## «""v I, 

# 4P"", Harold Pedall, Section Head 

# d P**J~** Itt""""'- 

## Product Chemistry Review Section 'I'



## 1. The submitted product chemistry data requirements for 

## reregistration of this end-use product, Prep Plant Regulator For Cotton, Reg. No. 264-418, is aduate. 2. product chemistry data requirements pertaining to Series 63, summarized in the table below, is adequate. 3. The submitted product's label EPA received 1/23/96, is acceptable.**~,** 

## The**s~mitted produot~s**  

## C$F, a. 

## basic formulation dated 12/19/95 is acceptable, 

## All ingredients are cleared 

## tor use in ·pesticide formulations. 

## RlCOHMIHDATIOIS:
We have no objections to reregister this end-use product, Prep Plant Regulator For cotton, Reg. No. 264-418.



# 122

# •



# •

• 2 

## SUMMARYOF

## PRODUCTCHEMISTBYDALi REQUIREMENTSOF

## SERIES 63 fflYSlCAUCHEMlCAL PROI'ERIlES.MBlDNo. 

# 4392IJ5.!H

GUIDELINE VALUE ORQUALITATIVEDESCRIPTION REFERENCENOI7T1'LE
63-2 

## Color Waterclear 63-3 

## PhysicalState Freeflowing liquid. 63-4 

## Odor Odorless 63-7 

## Density. 

## BuIJ: Density. 1.3045 orSpeclftc Gravity 63-12 pH 1.69 63-/4 Oxidizing Or Does not contain oxidizing or

## redudns agents. ReducingActum 63-15 FlammabUitylFlame NA 

## Extension 63-16 Explodabl/ity Does 

## not contain anyexplosive mateTinTs 63-17 Storage Stability Stablefor a minimum of 1

## year. 63-18 Viscosity 7.838 cSt 63-19 Miscibility (With NA hydrocarbon Solvents)**63~20** 

## COTTOsicn Non corrosive to stainlesssteelorplastic. S/Ight corrosicn Characteristics to mOdsteelandaluminum.



# - 63-21 

## Di£lecrrlc Breakdown NA floltnge (EP only).

ee: 

### saml Malak end**Cont~.l** 

### file (Reg. No.**264~418). 1505~:RD:RSi:PCR$:C$-1:650:S.K.tak:11/12!96:70l-308·8392:<264·41B>.** 



# 123

## DP BARCODE: 0226708 CASE: 003396 SUBMISSION: 8499337 DATA PACKAGE RECORD BEAN SHEET DATE: 05/31/96 page 1 

## of 1 

# • * * CASE/SUBMISSION INFORMATION 

# * 

# * * CASE TlrPE: REGISTRATION ACTION: 674 8 NHTH 

## RESP-PROO SPC DATA RANKING : CHEMICAlS: 

# o POINTS () 099801 Ethephon 55.4000% 10': 000264-00418 PREP PLANT REGULATOR FOR COTTON COHPANlr: 000264 RHONE-POULENC AG COMPANY PRODUCT MANAGER: 22 

## CYNTHIA GILES-PARKER 703-305-5540 ROOM: CM2 229 PM 

## TEAM REVIEWER: WANDA RUFFIN DAUGHTRY 703-308-8171 ROOM: CSl 

## 1K4 RECEIVED DATE: 01/23/96 DUE OUT DATE: 07/21/96 

# * 

# * • DATA PACKAGE INFORMATIOK 

# * * * DP BARCODE: 226708 EXPEDITE: N DATE SENT: 05/31/96 DATE RET.: / / CHEMICAL: 099801 Ethephon CSF: Y LABEL: Y 

## .: TYPE: 001 Submission Related Data Package 

## SIGNED TO DATE IN DATE OUT ADMIN DUE NEGOT

PRQJ DATE: 08/29/96 DIV:RD // // DATE: BRAN: RSB / / / / DATE: SECT: PCRS /**~/** 

## / / 

# :R;**~ ~** **~**


# • * * * DATA REVIEW INSTRUCTIONS 

# * * * Please complete 8 month reregistration review of product 

## under Ethephon RED (0382). Thanks Attached: MRID 43920504 FOR SERIES 61, 62 AND 

## 63 PLEASE RETURN TO W.DAUGHTRY, CS1, 3RD FLOOR, SRRD-7508W 

# * * * DATA PACKAGE EVALUATION 

# * * * No evaluation is written for this data package



# * * • ADDITIONAL DATA PACKAGES FOR THIS SUBMISSION 

# * • •

# ~**~**

DP BC BRANCH/SECTION DATE OUT DUE BACK INS CSF



# 124 LABEL

# •

• MEMORANDUMUNITEO STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D,C, 20480

OFFICEOf'" PREVENTION, PESTtclOfSAUD TOXIC SU6STANCeS 

### Subject' EPA File Symbols, 264-263(0226719), 264-543(0226721), 264-267(0226711), 264-292(0226717), 264-376(0226715), 264-257(0226723), 264-377(02267291, 264-380(02267261, 264-418(02267091 

## & 264-511(D2267061


## From: 

## t4ark J. 

## Perry, Biologist 

## Precautionary Review Section Registration Support Branch Registration Division (7S05W)
To: Wanda Ruffin Daughtry 

## Special Review and Reregistration Division (7S08W) Applicant:Rhone Poulenc Ag Company P.O. Box 12014 

## 2 T.W. Alexander Drive Research Triangle Park, NC 27709

BACKGROUND 

## Rhone Poulenc Ag Company has submitted or cited acute data for several products (listed above) in response to the Ethephon RED. The products are addressed in accordance with the acute toxicity batching strategy included in the RED document. Ethephon is a plant growth regulator used to promote fruit ripening, flower induction and other similar responses from treated plants.



## RECOMMENDATIONS
Batch 1: EPA 

## Reg. Nos. 264-263 & 

### 264--543


## 81-1: 

## Category IV (MRID 439205-01*) 81-2, Category III IMRIO 439205-03*1 

## 81-3: 

## Category IV (Based 

## on**~echnical)** 

### 81-4, Category III (MRID 418674-011 81-5, Category IV (MRIO 418015-011 

## 81-6: 

## Non-sensitizer (Based on Technical) * 

## MRID 439205-01 

## and 439205-03 

## received an abbreviated review due to the results of the acute oral and dermal testing on technical Ethephon.



# 125

# •



# • Batch 2, 

## EPA Reg. Nos. 264-267, 264-292 

## & 264-376 81-1, 

## Category III (MRID 439205-02*) 81-2, 

## category JIJ (MRID 439205-03*) 

## 81-3: Category IV (based on Technical) 81-4, 

## The eye irritation study cited to support this requirement cannot be located (MRID 00070086). As a result, 81-4 is a data 

## gap for, the batch 2 products listed above. The registrant may choose to submit a copy of the cited document for review, or cite alternative eye irritation data to support reregistration of the 

## products in this batch. 81-5, 

## Category III (MRID 00251542) 

## 81-6: Non-sensitizer (Based on Technical) 

# * MRIOs 439205-02 and 43920.5-03 received abbreviated reviews due 

## to the results of the acute oral and dermal testing on technical Ethephon. Batch 3, 

## EPA Reg. Nos. 264-257, 264-377 & 

## 264-380 

## 81-1: Category III (Based on Technical) 81-2: Category III (Based on Technical) 81-3, 

## Category IV 

## (Based on Technical) 81-4, 

## Category I (MRID 002486Sa) 81-5, 

## Category II (MRID_00251S42 

## & 00248658) 

## 81-6:**Non-sensitizer~,(Bas8d** 

## on Technical) /" \ 

## Batch 4: BPA Reg.

# NO~. 264-418 / 81-l, 

## Category 81-2, 

## Category 81-3, 

## Category**81~4:** 

## Category**--~ -~</~-**  

## II:L-tBased on Technical) III (Based on Technical) IV (Based on Technical) I 

## (MRID 00248658) 

## Due to the category I eye irritation observed in a 39.9% batch 3 product (MRID 00248658), 

## PRS has decided to use this study to support the subject (55.4t) 

## product. 81-5, 

## Category I (MRID 428727-01) 

## 81-6: Non-sensitizer (Based on Technical) Batch 5: EPA Reg. Nos. 264-511
81-1: 

## Category III (Based on Technical) 81-2: Category III (Based on**~echnical) 81~3:**  

## Category IV (Based on Technical)**81~4:** 

## Category I Requirement waived due to expected severity of eye


# 126

# •

• irritation testing results. 81-5, Category I (MRID 00029513) 81-6: Non-sensitizer (Based on Technical)

LlIBELING 

## Batch 1:


## 1. 

## The recommended signal word is caution.
2. 

## The recommended precautionary statements are as follows: Harmful if absorbed through skin. -Causes moderate·eye irritation. Avoid contact with eyes, skin or clothing. Wear long-sleeved shirt and long pants, socks and shoes and chemical resistant gloves (such 

## as Nitrile, Butyl, Neoprene, and/or Barrier Laminate). Wash thoroughly with soap and water after handling.
3. 

## The recommended statements' of practical treatment are as follows: IF 

## ON SKIN: Wash with plenty of soap and water. Get medical attention. 

## IF IN EYES, physician if

Batch 2 Flush eyes with plenty of water. irritation persists.

1. The recommended signal word is caution

. Call a

2. The recommended precautionary statements are as follows: Harmful if swallowed or absorbed through skin. Avoid contact with eyes, skin or clothing. Wear long-sleeved shirt and long pants, socks and shoes and chemical resistant gloves (such as Nitrile, Butyl, Neoprene,**and/o~** 

## Barrier Laminate). Wash thoroughly with soap and water after handling. 3. The recommended statements of practical treatment are as follows: IF SWALLOWED: Call a physician or Poison Control Center. Drink 1 or 2 glasses of water and induce vomiting by touching back of throat with finger. If person is unconscious, do not give anything by mouth and do not induce vomiting. IF ON SKIN: Wash with plenty of soap and water. Get medical attention.



# 127

# ) 

# .



# •

• Batch 3 

## 1. The products in this batch meet the criteria for restricted 

## use classification due to eye irritation. The PM Team should decide if restricted use classification is 

## necessary or 

## if alternative labeling will allay the requirement for restricted use classification. 

## 2. The recommended signal word is danger/peligro. 3, The recommended precautionary statements are as follows: Corrosive. Causes irreversible eye damage and skin irritation. Harmful 

## if swallowed or absorbed through skin. Do 

## not get in eyes, on skin or on clothing. Avoid contact with skin. Wear coveralls worn over short-sleeved shirt and short pants t 

## socks and chemical resistant footwear, goggles or face shield and chemical resistant gloves (such as Nitrile, Butyl, Neoprene, and/or Barrier Laminate). Wash thoroughly with soap and water after handling. Remove contaminated clothing and 

## wash clothing before reuse. 4. 

## The recommended statements of practical treatment are as follows: IF SWALLOWED: Call a physician or Poison Control Center. Do not induce vomiting. Dririk promptly a large quantity of milk, egg whites, gelatin solution, or if these are not available, drink large quantities of water. Avoid alcohol

. IF ON SKIN: Wash with plenty of soap., and water. Get medical attention. IF IN EYES: Hold eyelids open and flush with steady, gentle stream of water for 15 

## minutes. Get medical attention. 5. 

## NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate**?fo---use~gastric** 

## lavage. (' Batch 4 / 

# "-

..... 1. T1'i'e--"products in this batch meet the criteria for restricted use classification due to eye irritation. The PM Team should decide if restricted use Classification is necessary or if alternative labeling will allay the requirement for restricted use classification. 2. The recommended signal word 

## is danger/peligro.



# 128

# •

• 3. The recommended precautionary statements are as follows: Corrosive. Causes irreversible eye damage or skin burns. Harmful if swallowed or absorbed through skin. Do not get in eyes, on skin or on clothing. Wear coveralls over long-sleeved shirt and long pants, socks and chemical resistant footwear, goggles or face shield and chemical resistant gloves (such as Nitrile, Butyl, Neoprene, and/or Barrier Laminate). Wash thoroughly with soap and water after handling. Remove contaminated clothing and wash clothing before reUse. 4. The recommended statements of practical treatment are as follows: IF SWALLOWED: Call a physician or Poison Control Center. Do not induce vomiting. Drink promptly a large quantity of milk, egg whites, gelatin solution, or if these are not available, drink large quantities of water. Avoid alcohol. IF ON SKIN: Wash with plenty of soap and water. Get medical attention. IF IN EYES; Hold eyelids open and flush with steady, gentle stream of water for 15 minutes. Get medical attention. 5. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the**us~** 

## of gastric lavage.

Batch 5 1. The recommended signal word is danger. 2. The recommended precautionary statements are as follows: Corrosive. Causes irreversible eye damage or skin burns. Harmful if swallowed or absorbed through skin. Do not get in eyes, on skin or on clothing. Wear goggles or· face shield. Wear protective clothing and rubber gloves. Wash thoroughly with soap and water after handling. Remove contaminated clothing and wash clothing before reuse. 3. The recommended statements of practical treatment are as follows: IF SWALLOWED; Call a physician or poison Control Center. Do not induce vomiting. Drink promptly a large quantity of milk, egg whites, gelatin solution, or if these are not available, drink large quantities of water. Avoid alcohol. IF ON SKIN: Wash with plenty of soap and water. Get medical attention. IF IN EYES: Hold eyelids open and flush with steady, gentle


# 129

# •

• •

stream of water for -15 

## minutes. Get medical attention. 4. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate 

## the use of gastric lavage

.



# 130

## DP BARCODE: 0226709 CASE: 003396 SUBMISSION: S499337 DATA PACKAGE RECORD BEANSl!EET

. 

# * " "

# CASE/SUBMISSI~';FORHATION* * 

# * DATE: 05/31/96 page 1 of 1

CASE TYPE: REGIS'l'RATION ACTION: 674 8 

### IIII'rH 

## RESP-PROD SPO 

## DATA RANKING : CHEMICALS: 

# o POINTS 

# 0 099801 

## Ethephon 55.4000% 10': 000264-00418 PREP PLANT REGULATOR FOR COTTON COMPANY: 000264 

## RHONE-POULENC AG COMPANY PRODUCT MANAGER: 22 CYNTHIA GILES-PARKER 703-305-5540 ROOK: CK2 229 PH 

## TEAK REVIEWER: WANDA RUFFIN DAUGHTRY 703-308-8171 ROOK: CS1 1K4 RECEIVED DATE: 01/23/96 DUE OUT DATE. 07/21/96 " " " DATA PACKAGE JJlFORKATION " • • DP BARCODE: 226709 EXPEDITE: N DATE SENT: 05/31/96 DATE 

# RET.: / / CHEMICAL: 099801 Ethephon

# ~ TYPE: 001 Submission Related Data Package CSF: Y LABEL: Y SIGNED TO DATE IN DATE OUT ADMIN DUE DATE: DIV:RD // // BRAN: RSB / / / / SECT: PRS / / / / REVR: // // 

## CONTR: / / / / NEGOT DATE: PROJ DATE.

" • " DATA 

# REVIEW JJlSTRUCTIONS " " " Please complete 8 month rereqistration review of data 

## product under Ethephon RED (0382). Thanks 81-1 and 81-2 citing KRID 00257032 81-3 citing KRID 41685901 and 00252902 81-4 PHS 

## gave approval for registrant to cit

.. data**~conducted** 

## on 264-380 (MRID 00116670 and 00248658) 

## 81-5 citing MRID 42872701 81-6 citing KRID 00151056 and 00257032 08/29/96

# ~**~**

for

PLEASE RETURN TO W.DAUGHTRY, CS1, 3RD 

## FLOOR, SRRD-7508W

DP BC 226708 

# * * 

# * DATA PACKAGE EVALUATION 

# * * 

# * No evaluation is written for this data package



## " • • ADDITIONAL DATA PACKAGES FOR THIS SUBMISSION • • • BRANCH/SECTION RSB/PCRS DATE OUT 05/31/96 DUE 

## BACK 08/29/96 

## INS Y 

## eSF Y



# 131 LABEL Y

# , Unft&d S't8t8t IIW'irotmmlUfProtection

### Agency Fofm Approved

. 

# w....,..",. DC 20460 OMS No. 2070- 

### 0107,



## , CERTIFICATION WlTH RESPECT TO 2070-0057 

# " DATA COMPENSATION REQUIREMENTS ApptOVid Expires**3~3,·96**
Public ro,oortino Curd., for**th~** oo/lOO'l:iGn of infafTl'\Otkln 10 fttimatfK1: to**~G.** 15 mirlutG4 per rooponoe. itJcludlng ti:tnn for reviewing il1structlOnl, searChinG oxmttng data sourcer. 

### Ofthemg and maintaining the data nOGdod. and compllltklo and reviewing the coll&ction 

### 01 ilformatiOo. Se.1d commeott

## IWQ8t<tino the buroon 

### '8fti'nat4I or any oth« Uptlct of 

### this cotIaetk:tro of infonnation, indutSinO SUOgatiOn!: for reduclno 

### this bunkIn to. Chiaf lritormatloo Policy Branch. f'M..:l33. U.S. 

### Environmsrrtal Pr01tc:tlcn Agency, 401 MSt., S.W., WMl)in;Con, DC 20460;and to the Office of Manaoement amf 

### Budget. Paperwofk Reduction 

### Pto;oct (2Q7()-o1061.WuhnQ'tco. DC 20503.
pte

...

### fill in blanks b8klw.



### c:•....,.....yN_ Comp""V N"

......



## Rhone-Poulc:nc Ag Company 

## 264·
!",oduet N.",. EPA Reg. No.

## PREPTl~ brand 

## Ethepnon fOf Cotton and Tobacco 418 I 

### CGrtify that:


### !. For

.. en study cited in 

### SUppOrt of rOiPstration or 

### ret'egistratiion und

..the Federalinsocticide, Fungicide and Rodenticido Act 

### (F1FRA) that i$ an fXclusive us& 

### stUdy. 

### Iam 

### the onoml 

### dBtu submitter. Of 

### Ihavo obtolnod the written plN'lTlilsion oftho original da'tllvubrntttet to citetha1 mtdy. 

## 2. ThattoreaCh study 

### cited 

### .In 

### supportof legisttation 

### or...-.gistration under FIFRAthat is

### NOTan exclusive usestudy, 

### I am the original data submittllr, 01 IIlAve obtained thewritta'l**p~** 

### ofthe

### original dataaubmitt8f, IN" 

### Ihave notifi(ld in wnting thO 

### eMJpanYlirIIl thatsubmitted 

### data Ihave

### cited and 

### hi

.... of'ftndto: fa) 

### Pay cornpensatjonfor thosedata in 

### accoroonee W1tn sec:t1ONi

### 34CJllllFI and 

### 3Ie)l2)IO} Of

### fIFAA; and (b) 

### Commence 

### n&got.lion to Cle't8n'nntt Which 

### Cktia are subjectto

### tn. compenc.ation requitement offlfAA and the

### amountot eomperu;ation 

### due, if

### any. 

### The companies Ihave notified are. Icheck onel

( IThe companias who have eubm/tted tho studietJlisted 

### on the back

### of

### this form or ett8Chod diem;, Of 

### indicated ontho machod**~RequirGm."t$** 

### Statu.and 

### Reoifmtnts' RaspooaeForm,**~** 

## 3. That Ihave prmousty complied with Section 3(cl(1)IF) (IfFIFRA fortMltUdlesl have cited In 

### support ofraglstmtion Of 

### fet09istmlon undet FlFRA.

SlQnlMO

# /~;(;:; ;j,2;!t'/ Otto 

# .1/ j/7 L,

NIImO II(>d TIlio iPl

.. u TYllo C<t fl'nnll 

## Ga i 

## 1 Powell, 

## Regi str'ation 

# . , manilger 

# . GENERAL OFFER TO PAY: 1herebyoffor and ogroo to pay oomr;ttne!l1ion 

### to otherPO,..GnS, 

### with 

### rngilrd to the rt'gistration 0( 

### rereoisttation of my 

### productS, 

### to the extent required by AFRA semion 31cll111Fl and 3{c}(2HOI.

SlIlMlUr. 

## •

# ~/~d/ ;,i;1:1t-,4

...

## ,. '



# - N_.m Tlv. iPf

..... ryp, Of t'MU 

## Gail Powell, Registration rlanager'



# ,

132

# •



# • £l'A fUe 5""",,[/Rea. tb. 

### _-,2",6",4·",4",1",8

__ _ ::lata 

## or Iloolieat.lal

____ _

..... of Pr::c!uct: 

### _-,P.;;R",E,-P t_m-"B",RA",N",D,-,-ET",H",S"P",HO",Uu;E,.ORc...J.C",PCLTI.uO..,NI.JlA.,NDJ.-'I"'08w A IJ,C.l.CI.lO

___ _ ADolicam::'s 

# u.... and Address Rhnoe-pouJQQC 49 Company 

### P. O. Box 12014


## ReSearCh Trjangle Park 

## N C 277Q9

1. This 

## &;IPlicat.ion is**~** 

### by 

### all 

## dau lNt:Iaiu.ed or cited in the applicat.ic:n. 

### In addition. if 

### c:ite--4l1**~ions** 

### are irxiic:aud. this**.~ic:aticn** 

### is 

## sucponed by 

## all data in tlUI 

## Agency's files that 

## concern the 

### propertt" 

## or efteees of 

### this 

## ort'lduet or of IJW 

## otIWr oroduet tl\at 

### 1.1 

## ictent:.lcal or aucstAnually sUailar. anc1 that 

## is 

## a. of 

### tna types 

### of dat.a that 

### WI:IUld be 

### AqUirec1 

### to be II\CIltted 

### if 

### this a;tplication 

## IIOl.IiJt\t the 

### initial nqistration of • produc:c. 

### of idenuc:al or 

# .war c:C"""lIldon 

### en::l 

### intandeC1 

### uses un:!er the d.tta 

### requitatwtntoS 11\ 

### effect at the

## ~at of

## ~al. of 

## th.is epf11ic:aticn. 

### 2. 

# r certify m,at.* 

### for each 

### swcty cited 

### in supoort. 

### of this 

### appl1cat.ion !or requtrauon that 

### 1s an exelUS1" UN aCJdy. I have obtained 

### t!'le wt'1t:.'!en pemlSS1c::n of the orlQinal data autaitter to Clta t.hat seudv.


### 3. 

### r certify that. 

### for • ..ch 

### study eit.ecl in supgort. of 

### this atlOlicuicn 

### for t'egl.$uation that 

### is**~** 

### an uclusivoe use atl.l:ly:

r have 

### Obtained 

### d1e 'W"t'"it.ten 

### pem.ission of 

## t.tw. oriqina1 data 

### sutmitter to 

### cite that ST:Uay':**~** 

## r have nOclUed in 

### writin; the 

### CXJ'I!q:I&nies 

# wno have 

### tNbSitted 

## !'!au I have 

### cited to SUCD01'1:. 

### t.I'Iis 

### aopl.icaeion and 

### haft 

### offered to: 

### (a) Pay**~Mation** 

## for .- data 

## in •

__with .-ion 3(c)(ll1D) and 

## 3(0)(2)(D) of the 

# """Rl, Il'tRCt:tci6,,, 

## fUngieide &N:I 

### AodeIKicidlt Act: 

### and: 

## Cb) 

## OJa.nee MQOt.iationa t:o 

### deteDllirw \It\ic:b 

### data

.. IlUbject 

## to the 1X:iiII*'WAtUxt 

### requi,&i&h't 

### of FIFRA and the II'Dltlt 

### and 

### tam. of CX2'IIpeI'INdcn due. 

### if 

## any. the CCDIpImies 

### t h.ne 

## notified an: (c:neck. c::JrW)

### ~ 

### All**~i**

### .. lisud 

## on the Peltit;:ide 

## c.u SUbl:itters t.1.st for &11 

## actlve in;ndittrWl 

### c:cneained 

## in my**~** 

### (C1C.-.ll lIIft.bOd 

## or eiu-.ll opeion um.r**S.l~l.ve** 

### Ket:hC:r:I). {Also 

## sum t:he 

## (itlnerel Offer to Pay Stat:IIIIeM bel.ot.) 

# I<J 'IIlOM c:aoponi

.. _ 

### l..w. _<<ed the

# ._1

.. wtrlell I "... 

### ciUd (Sllecive _UlOCl)


# ""to 

# 12/ 

# zrirr r· 

## Registration Mavager 

# .....• 

## •••• • • 

# ....... ,
•••••!t • • 

### I**he'-"~** 

### offer and

_ 

### to -... iii 

### Me-1Cll 

### to

# ~;rnr-;'';';;d';''tho

# ..-"".1 of

# th1s~"",I1"'iiS\'~ to 

# !:he,:'

- roqu1_ by 

### FlFJIA """. 

## 3{e)(1)(DI

## ":~(2)~ 

# d' -:.'.: ""... {"/?Zb;- Sianatw:lt

# Jf&,..1I1W<-~, r ' • Title 

# i{.;u/ryiim.jl{ry'Y"j'X:"·

(1<>rU 1985) 

# ...... 

# . ..



# .. , 

# 133

# ... '"m.'" .OMB No• United StateD



## _ Registration Numbltr 

# &EPA Environmental Protection Agency 

# ..i Amendment 

# 251318 Wuhlflgt:on. DC 20460



## _ Other !for 

# - • I

. CompanyfPrcduetNumber 2. EPA P,oduot MaflilQM 3. Proposed ClllHlficallon O<A. 

# "0 '<ow. 

# [ij"- 

# o Rntric.ted 4, Compony!Ptoouet (Nomo) 

## PREptm BRAND ETHEPHON PM' 

## #22 

# .:.- 00' t (Include

### ZIP Ccd,d 

### 6. Expedited**Rovlew~** 

### In 3Ccordance with AFRA Section 3(c)(31



## Rhone-Poulenc Ag Company (bj{i). my 

### ptodtJ(lt 

### Is sImllaf or identle:alln composilion and labeling 

### to: 

## P.O. Box 12014 EPA Reg. No. 

## Triangle Park, 

# Ne 27709 

# 1

aha« if

### thi!J

### is • nilW tKidT4u 

## Product Name 

## SOC

## rton

- II

# ~ 

# Am.""""". ,,,,,,onb"ow. 

# D Flnal printed labol, in ro8pGnH to 

# o AaaneyJaUilt datod Rewbm/.aion In totpOnftl to Ag<l'fWy loU<1t dlltod -M6 TO(,J" Apptfoatlon,
[ "otWealien· Explain below. 

# o Other· ExpiO;in b%w.

UItO eddltional pagala) IfMeo,oaf'(. lRir .oetion I and Sltction 

## n.} 

## Revisions to label as required by 

## Ethephon RED, April 28, 1995 Added "Do not mix \'Ilth Armnonium Thiosulfate Statement" Modified statement about "do not apply if 

## rain is expected"



# .:J!!. 11. 

# , 

# .., 

# ,

# ."
Peck$gino 

# !""'" ,- Peekaoing 2.

## r.",. of Contalnet 

# 1,,8::°'

- Yeo 

## v"

# ~M". 

# I N. 

# [ No Pla.tlc Glao. 

### mU$t 

# I**~~ir.'':,** Nt.. pal If

# -v.,- No.per 

# P."" wgt. eonl4!net Pack&ge wgl oonlaitat Olhot 

# lbe- 

# ,

# I'~~-~' I'.' 

# '0'""" " R

... 

# IIII Lob$l 

# 0 CGnlluner 

## 1, 2 5, 5.0, 30 110 produo:\t
6. MannotIn Which Label I.Afflxotd to Ptoduol 

# I-

# ~~~~. 

# UJO- 

# .,, ,A 

## iner conbin< 

## label
•-IV

1.**CO"'~"o;n'** 

# 'ro.o

, to**prno~** this, 

# '"'Gail I Tl•• Ate, Code) 

## Powell Registration Manager 

## 919/'
Certification

## ":~: 6.0ilb/Applleation Ioertify thallhG mlomonl. Ihave mocl, on IIUII- form ood &II attaohmanw IhorelQ .,.lru', 6¢¢Ulate and

### c~. 

## !<'Gotv' I I1l4teme"t ffaVbe punishabfe bV fin. Ot ImprillQnm4nt Ofl' : 

# ,• (k'lfmpedJ 

# 0;;'.-'''''0<'

.. • , , 

# ... 

# .. 

# 2.0""";8 J 

# IZ**~**j

# j 3.Title 

# ..:

# ..' 

# , Registration Manager 

# , -, 

# , 

# - ,

•••• 4.T'iJ)ed Heme 5. Dale 

## •••• 

# , , ,



# .. , Gai I Powell 12115195 1 ':lA

# "'A~"'V,"'" ....... M 

# -

. Cop, Copy



## ,**~--"----**



### PAPERWORK REDUCTION ACT NOTICE and INSTRUCTIONS

('- 

## : ;:'

, "**~** 

### PAPERWORK REDUCTION ACT NOTICE; Public FI.>pordng hurthn (Of lW$ Milcction

### afInfQrmlition!$**I1Hl~l4d**

### to**1'I\lor~** 0,85

### hour p!!>f**rOSjmI'l$O.I~** time for reviewing ilWw;;-&m;, lifMUQNnQ eldlitinu dillS 'loom"$, Uillh6ring lind mmnwlninu itm data Mmlad. lind eompllHll'tU Iffi<'J rt«k:owlna Itw ooifIMtWn of !nfIJrmaliof!. Send eOi'1lrfW!lllll 'II'g&rmng 1Mbtird!tl) otttiml!!9 (jf**~51'<Y Qt~r**  3l:jt'l'Ct of lhill ocllox:.ticn ofil'l/orm&thm. Imludil1g**iW\l~l:tlmijl:** f(;f riduclhJllhia- burdtln. to ChillY, InftirrrtMJ<.m Pelley lJrtmcn. 121 JSL lUL fnvirOrlm$ntcl**pff)t,,~tlon** AU!irwy, 401 M Stro:et, SW, WMhingtOh, 

### OC' 20400.

## ~:.~~:~~= Thi. form iv to beused lor d1 appliclltiun!t for now r<tgi1.tuflon, eM 

### uw. forogiSlftltiQfl, bf'landmKIt. fgwbmiulon, to UPP#(lllll1:m1l printed Iab-.Una, flirtlgislnltitU!, etc. In ordllr to prac(llIs tin Ilpplieilllll;ln (or "ntlW reglstration llUbmiued on this form. the mtwt**ae~ny** tho tipplha&n; 1. Cn$ution'with f\oeplWt to Cltatkm "If Data iEPA Form 8570-29j. 

## n( flot i.t>(arr;ploo by 40 ellR 152.S1 rbl 1411; 2:.**C~** Statemant01 FOffnUfIl IUA F«m 8510.4jl 3. F¢mWJatof'. Extm"lptiofl Sutorrwnt IEf>A Farm a57o-271; 4. Ave GQpi••ofdreh**IISb~;** 5. Tht

..**o~** of anydatfl aubmllted; 6. Aulh4ti141lrm IOUOf**WM~** app'Jnlbfo; 7. Mtltrlco, where appIh:ablo. of l.ah.tmg • lal»!lng $howd flrllit bo oobmitted'n theform 01 arllft labula wilh WI l!pJ)IIeatioM lor Mill' fegi.lfation. Suoh dralt llI'bclu maybill leJffi text 01'< 8.5x 11 ineh**~** fOf lWbmili'1rion Of It fMlekup of Ih. ptep(l1I4d lebel, If Pfapilf«l fOf moekup. it lihGuld be WilY Q to' fbe-IDuto stOfnijO In liIn 8,5 x 111M» f1!d. Mowup looeh IlgrJr,/j/ilnuy tmaller Ihan 8,5 x 11 lMh

... hould be mourned 4n 8,5 (Of 1Il.!!.m-Jse1on. Dau· Oal4 lJuumitted In $UPport of lhill**~Iill(;(llion** I1I!J1It ba lIubmltl0d In t!(!cordnff\!e with 

### PR NOllee 8G·5.

## 1~!lillIlQli!- This lIeclion

## mu~1 bll tomplMM. '" appHetIWlI. lor fill .tyi$lrlllkm action.. 1. CompaoylPfodual Number· lmiert your C{)I'I'!p1llnY Number, IfO'ne hill\l, tHHm $!imgl'!ed by EPA< ThilO number may hav

.. bdcn 4a$lgnod 10 vcu M <l 1;11.1.:,\ foglll!r<mt, • di"t,lbutof, 

### orn. 4fttHlllIIbfi1oftn'wnt. If)'Ottf (If<xluot 16 ftlwsum4, InS<f1t ltllt Product

### Numb.t. 2, 'EPA PtoductM]Mljgu· 

### 1/ kMwn, rm in tOO Mm¢ and 

### PM 

### nvmmu O/IM EPA Ptod-u411**M41na~r.** 3. PtCflOHd**~atkm ~**  $pwly Ihtl prQPoll!id clll!lMfielliiofl <)1 thW produot. ProductN4tM • Cnt$fthe lXlfflP/$1w pf(uJum !'ll'IfWJ of**this~"** Init wUl J;j)pH( ontheIshL The NIITI'II mullt Ia**~** to tWA ptoduM rmly. 

### Ou.tkmof /iGI'l'IU I; Mt POfmtUnd &rIWnu prodW;lll. 01 

## \ht- SlumO t;orrtpbny. Do !'Un Incll4do GAy brand ntltml or**~** fiMl**d~Gf'l$,** 5, Nana and**A~** 1'{ AppUHnt·Tn. ffiI!nl! or

### tNfirm trrJWfS{;lO lind**lIlddr~u** 'Mwn In your application hi' tMpO}tUIn 

### o/fl®to**)V~** 

### the rcghrtrotion wm 

### b. IUlJmi. Ifyou M# ru:lIJI1Q inbflhW( M tlnolilsr PMty, you."-WSI QUbmlt lru\Mliution trom lhat pMty tt! 

### m:t

# torthOrn In**n~Wtltrlltien** matt.,.., An IIIPpfiOlint not flttkflng In the Vnitlild StatO$

### must h\lvO an euthoriu4

# *trt ta$kling In Ih. Urnlmf SUit" to act (w tmrn In "dl r&glStfliticn 

### martel". Tho IlUM 

### 4nd coftlPfelv mcillng liddre;" o( wch tin llGt'nt !'mist**~an'f** 

### 1m**zpp!¥:uti!l~.** E:qadit4tl

## n.llkw**~** F1FRA**~tlon** 3- (ciS (S) prov\dh fw o;qadlWd ftviaw**e13pp!iClf~** Jet( u:oi!.l'lrlltlt;m, Qf armmdmllft{sto**,~,.''''**

## ,.';w

.. , thatMit Milltlfotidtlntkltd to ather PMlticldo PrOOutt!l Ihtlt {ft. currently fOiP1rtornd wllhiJHj EPA. In orderfllf yoor

### iIfIP!leo1i((n to hll expediud review,**~** mu$1: pfovkfJ.l U$ with lftn EPA Reolufa:!on Numbnr and pto4uct I'tijffitJ of thli pmdu-ct 'IOU bdew 1e**~** to**,,~'"tl'"** YOUf pfudlJC't. 

### TIaproduCI must t;., .Jmillir 01**idorrtie~** kl both Icrmu!&tioo and IlIb{lltld U§fll.

# ~~~~~~.:·~ThI1I: !li\UJion ml.Ult bIJ lXmlPfolttd ror eiI

# ~lIti'H,\' zubmJusd to emond tho f#WSITiiUK-11 Qnty fit " CU"«ltly

# ~at«od p«!>duct lor III rqlNhrr!lslliQn if! f4!!p0ffll. 10 lin AuerniYletlllf, lor "o-lifiallilcrato 100 Ag¢tU:ly, lor lhe**1IVbmi~** 

### cUIfill' printed lllbaUnu. fIX" fer any bthH

### "tion: lMI pnta!MI «> (I pP!!llifle R?A·rtW*I!![r-4 prMWlt."ihhI Melien 1$!l2.! 12

### k!uJlod'h)r

..new**~atkm** fot

1.**~t** of tubmIHkm« Ctui-ck tho**~l,l4hlll** Woe" and**Ptow.l1~** I/;/I' Aj:J91\C)'.I<oIlUot43Ut,ilItPIUc-priat9. Frcvtd. Itbtll'll expl_ti<m (t/ the**putp(\{I4I~)** fOf tho aubmisskm. wah 011 -Om additi"n afa mill, p!W1 (If or
.... ,?**iltpl)cdy)~; ~arrnmd**  tho Confldllntilli SUltmlwnt

### of Ycfflm/o by"."; "fefeWlllmt(cn :lubmiHkn"; -QWafD/lbbei ro\4tlon of IN'" dtrllctlont:.**~** Atttwh tI l16ptlfaf9 {Mite ileddiuonal $pllce III nheded,

1.
2. 

# '" 4" 5. L_tfOl1 cl 6. Mllfl-IWr in 

### CuntaiM-' IllfotflVltlcn}· Thl1. Soction

### mtl~t bl<

### c~~llIld (Ot dIl aPf}liclIIh,>n& .ubmittoo tn COffM\CtiOf) with now

11 y¢lJ( pre-duct will he- pllck&g&d In the- itWlcaltld packaging tvP*1I,

## ~~::'~,:~~rrurnb'r pili retail comllir>IIL eOl'!tmMf In wI-Jell. pn:.0ttct W#I OJ'! fWlrht<l!d, oftfuJ MI eQl'1hlflt$ inforfwnioo 

### tor VOUI pf>MUcr. Mtoont9f\-l$ (}I @lI fe-uri <:xmt&l/Wffller VWf prWuot. location 01 the**U~ilI** dlf(KlliolW fer yi;i\lf prtlduec IndWat&d Ih5 fTh)thod prOOtic! lab,u 15 ;nmctw-d to tatllil eonUilfWIt.**Fo~,** 

### ,,,... OM. No.



## , Unlted State. 

## Registration OPP Id.l'ltlft.r Numb.r 

# oEPA Environmental Protection Agency 

# ::L Amendment 

# 251318 Wethlngton, DC 2.0460 

## Other

,for I

- 

## I 

# 11. CompanylP,oduet Number 

### 2.EPA Ptoduc:t M4n&g0, 3. PtOPC)l«l Cfualficlitlon 

### "''''41 N 

### SH,k" 

# [!]NOI\CI 

# o R ••

trlcted 

# 14. CompanyJProduot

### tN«no) IXi**l{\{f;f~i!** 

## 'lHePdO" 

# PM.**~,** ,i 

## 121 

# .0' t Ifnclud. ZIP CorM 

### 6. expedited Review. In accordancewith FIFM 

### Section 31c(3)**'U:~;;i0~** 

### lenc q/ 

### (bUll, 

# mv productIs similar or Identical In oomposltion and labeling

,

# ,**~** !L 

### dox 

### 1 1/1 to:



## , "i(j·1rqi(; 

## tk f"- 

# , ; ;<) 

### EPA Reg. No. 

# r ,le 

### , i**~** 

# ICh«:k Ifthk1#• tlqW.ddrHit 

### : Nam.
I

- 

## If

# ~**A~""m'"t·"'''.n'''ow.** 

# D Final printed 1&btIlt !tII '''1'004l1li to**~** 

### Ag.noy ,.u"

# d

.... Resubmi.sion In r•• pons. to AoortGy latter dotlld 

### ·Me Too· Appfuunion.

- [] Natifloati(){1' Explain balow. ] Othel' explain balow.

,_ V,e additional PIfIOOIII)IfMile"lIry. Ifor '"tlO(l Iend Seetion 11.)**~~,_:.,** S '; 

### ons to 

### ]tlb(:i Ss ' 

## , 1(0'i! 

### A:;t; i '"i 

## ,**~)!'Qn** 

# , , ---. 

### , ,J', c 

### Add(:0 " 

## mit mix 'nj 

### til !V,T!JI1;**d~'** 

### Ihi'Asul16tL " "

- 

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'c ;'4**;\~** 1

### l' j 

### ,:d c,tdlf,'i!'cnt e)0Zmt -'.11) 1\(;t 

### :;:';! 11 !t 

### rain 

# cC " ;:Xj)!:::t<'ij"

I

# -iii ".

..........WO

.. Child·Rofil.tant PackaginQ 

# , i

# r**~~W.**

# ""'woo 2. TYJH ofContainer 

# t[:" V

..

# ~~W**~** No 

# IlL N. i PfNtil;l Gin_ 

## *" t/onmult 

# 'N'

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# I**~"\**

# .."

. No.

# P" ''PM 

### IHI aubmlttfld COl'ltalll" wgt Other 

# , [i] 

# c.:...1N.t' 

# o Container c

# '~""', c 

# :;n !

## H, 

# :::3**g;:c~.** ' 

### ;:" ';



### -- ) 

# ,.",do" '- ",-,,' 

# - &. Manner inWhich label I. 

### AWnd tq Produot 

# -

# i~ l1J OihM 

## P1 iJ'<!-;" :a,",1pil,'t Ij hl1-(i 

### !t, 

## ",nth'''''' '''fGUinn 

# ,,,!,.,

,- IV

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## 11u. 

# L9!;," :;,1; 1 fiOht: 

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### t -<
- 

### t**{~!<' !~JtF\'je(**  _.14 ",i

# C.rtlfic.~on**::;!~** 

# ..**~** I CGrtify,that tho $tatemonU- I have mllda onthisform and all aUMh!Mnt\l th.-rt;to &fD trua, &of;lurato I**DCknowllld~ the~~~owinolv**  I

...or miol'lKflng .t.t&mantmayb.JiUni.htlb-le byfin. or bothunder ) 

### 2.S,g

..

# ,",.~!, i ! 

# la. lit/a 

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# -- • , i**<i>!j-;';'>'~** j;T >\l'1-1,(';" 

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# ·:'-1

,j :"v,,(' : ' 

# .' , 1'l&:: '

.. 1

..'

..... 

# -, Cop, V_ 

### tC",y

### PAPERWORK REDUCTION ACT NOTICE and INSTRUCTIONS 

## \- Publ!o fGporung burden for thl, (l"I!,etkm of infcrm.mJOI1I$ ostlmatoo to lIVOMQ<'! 0.95 MU! pM limo for tovi&wing iruitructiONI. lMlfl.lhing oxl'll!!nS dijt$ !(lUNC!!, !WIn-ring aM mail1tllininO tho dataMc4Gd. and**~et!ng** 

### and noH"otien ot il\fQrrNthm. S.nd "ammenla rllgi!lrillou tn, burden e&til:mlll:! Qf 111'1'( OtJafMlpocet of thl' ccl/llotion of l/lfornmtio",lMludlng

re4l1cing 

### thl.b,udon, to Chillf, Into-muilion PQlIe-y 

### annch, 121l6). U.S. Erl\llronmentel Protoction As-nov. 401 M Stu.st, SW, DC 20460.

# ~~:~:~::~ mil Iwm II to b. lI'W fM all cppne6tlons for new ,,,g:lstretion, end Ullb f61(lijl&tflll:ion, Mrntt'Idmilnt, "UlubrniUtoo, to am:>lie6t1olU print'" lalalmg, fefcgilHH;tion, lite. in ord,r to pr(;c.n lin I!f}Plle.etion for. ntlW !%lleuation 1I11bmittod on 

### tN. f01'lT'l, the mmt IWCOfflPm'l'{ Ina epplfcat{oo: 1. C.rtlfieatWn with**R.~et** to Citation I)t OM. fEPA Form 3510·291, IIf ml! O)(Mriptotd by 40 CFR 152.81 tb) (4)1; 2. Conlldentl$l Statementof FON'nUIa IEPA FOIffi 8570.4); 3. FOl'muhttOf'. EXllmption S'l1ltement IEPA Form 8570·27); 4. Avo eopi

.. ofdtaft lebeIing; 

### 5. Thl" copkta of anydat.l wbmlnerJ; 6. Authorizationlenor whore fIWlloab«l; 7. Matf1CN wheteepplloabl•• \""'''''''" of LIIb.ltng· t..t>.hn!il IIrnmld tif5t boflubrrtittod In tflll form ofdraft 100111, wlth 

### aU eppllC:4tiOrn> fOI new r.g1l1tratbm. Suchdrllft labds may typod label taxt on 8.5x 11 Inch papfl'for $Ubmlmon or \I' mcekul' oftlaptopotod 14Oe!. Ifprepared**for~.** It should be

### ,:3~~~~~B woy &s to tooiUtata atonllgo in 1m 8.5x" inch file, Mockup labets slUNfiesnUy small.rthan 8.5x 11 Inoh•• llhould bemoontad on

ff» $Ubmjuion. Data

- Delft #Ubrroittoo in .upport ofthis !fPplicntion must ba 'ubmlttlld In ACcordance with PR Nollea 8&-5,

## 1J!l','&I\flk:I1i~Jl!~~IQ.tl,l;;. Pllla"t; rillad tm. InstrucHoo$

## ~lIttld billow b"fore cwnplctinq this Df}p1Icntion, Flut dlltllffllinu tho typfI ofreg!IiUafu:ln in BloGk A, you ora IWbrniWng tNs Bppllcalion. For IIppjic!lticl1J1l atlbmlttod In connection wlth New RIIQI.tratlon actiona, S*Ctions IV rntJSl be eomp!.tlld bV duo applit.:aflt, For IIppllcllItJOns !H)bmlttoo 11'1 coMII:cUon with amllnd!>d r'legistretlonlWtionc. rc&Ubmftlt>oM, 

# I**~,.i""'.'M.** tllrcg!.uation" eto.• Seollol'l3 I, II. end IV mUlIt be comploted by th<:lllpplicant. tho approprlnte 8(;tlon for which you Mil whmittlng thia form. 

## l.i£I:!lQN.l- ThIll ,I.etlan tmJ!lt b, ocmpletod. 6S opplioabl., for 1111 rcgilltrlltlon ootieM,

1. CompltnyJPtoduet Number· Inurt your Compcny Numl;or, it 0"" 104; baen II$lrillmld by!PA. This numbar m4yhaveb

.. n**as~** lC you IS" batlc**r~"rMI,** • dhuributer, or lUI lin flBtoobtvrumt, If your product 1III(I!liSlered, inll6rt the Ploduot tJumbcr. 

### 2. EPA PTOdwt Manager -Ifknown, 

### fin: In the rum1' and 

### PM oombel of

### the EPA Produot Manager. 3. Propoce4 CI_We,lIon· Specify tho proroll.d dauiflc6fian Qf

### tN, produot. 4. Product Nal"Ml' tnter IN! eomplattt pr<!duct mime of thill pellUoWc at it wUI OPP04r on tM lobo!. TM rum19 muM b. ,peclID: to' thi$ ptodue-t onlV. OI.Ipfiestion 

### of l'I4tmIitie notpermittod (Im(Hlg pnxh.lclll of th, !HlmO eornpliflY, 00 not lneludo anybromd name or eomplU'l'{fil'lO d&5lglllfticns, 5. N_andAddr_ ofAwli¢Mt -,Tho 1\Mf\!t (If Ihe firm or I'HIIlIQI'I and OOdrus allown In YO\;lrIIppffeeilon i.thtl "orocn«firm to 

### wJwm tho regi,tr.tion wUt bc Illsuitd. If yoo are ooUng in boh$f Qf .nothar pony. yeu mUli\! wbmltljIJ\horiution trom thtrl partyto sotro:>rtMm in rOQidrlltlol'l ImItterl'l, An ""pliolint IUIt r.$MIno in tha United StatMi mull't hillY(! In lIuthorltad

# *"t rlmding in tho Unltod Satl, to aet for them If'i l1li ttolimallonnwtt.ta, 

### The!'I4!"M and cOfflp/eto mtllflnu 6ddr.a, of l\;lel!**MI.~nt** mutt gcampnnythis application, ft Expedited Re'ifew • ftFRA section 3 10) 3 IB) plo\lldes fCf expodited

### r.vl~w of "PpficAtiO(lll for r.glstration, or

### am4od""";"~":;:;~:~~;:::::':1 that .,ealmllar or WentjQal to oth6r pa,tlcld. prool.lct$ that lrr4 mlrrently t4gistOI'lIl'J with tho 

### EPA. tn <lrdor for your.8 ,xpGdlted I.view, yeu must proYkk/ u. withtM EPA**R~(Ji"rati(m** Number lind Jlroduot rtarfI& ofthtproduot you believe Is 

### sImRar to or. ywrprlXiuct. The productmuttbo limitltr Or identical inbrlth formulation lind lafaJed Ul1U.**~**

## rn.**lHI(ttl~** must b.**~.ttld** lor ell IlIPplkulticr1l1 avbmlttod to¥'niliM tn. regiltullJon oniV of II ClIrrllfltly**~teted** prOOuct for 8 rowbml![l4lgn In raspomo to .n**A~ney** letter, for notiflcatjon. til< tho Ag<ilfICv, f"r tho IItlbmi'lIftm offimtl printed )obetInu, for lor MY otMr lrotlon thllt p!.lrtillns ttl II iWru;!lIg EPA·mgl!lgl"d vrooy;t. W

... odon III!!RIm

## ta u
.... d for a MW appIicawm f<>l
Subjef/t of eubmIHion • Clwcll the IlJPPIlc6ble Woek and providll thll AgillM'{ilillel dBtOllif appropriate. Pro1!kfo III briof IIxplllNtion oftho !}U11H)$al,1 lor tho $ubfrn"lon, !lOch IllO "tho oddition of Ii dto, PUtor crop:**i~,dtv)~; ~¥fI,nd**  tho Confidentllll $totem.ntof FofJllUla by.•.**~; ~rer.gistr"tlon** **avbmililSffin~:** "g.neral leb$l**rovi~hm** ofu'o**directfotl$.~** Att&Ch 0 IlCPluot& P'1Qc 

### If ItddltiGllllillpaOe ill n.$dad• 

# ..... ,

## I~~:;;~~~

## It'HWno and ContainarinfoflTIIJt,on)

- This SlIction mustbo compilitad tor 011 epphcstloM eu\}mittlld In (;oMectkm with now 

## j. or lIP,,"oabW IWflOndmtmt=.

1, Typ. of**Pd~';Cm,cl;** the eppropricte bloc¥ If '(f.iUr ptOOV!)f wlll bG ptH:IkaQ«i In 1M IFldlceloU p«<ka(ling typali. lruficate1he ailtof tho**II'Id~~.tll** and numbJH pu rGt.ill cOfllGincr, 

### Tvra of RilWl.CMVtlller

-**i~tO~.** of**c~taifWr** If! which product wJII b.morkOllttld

. .L.\HtlltIon of**~1_~~ ~~'** tho loc1l;UQTI of lhe Jiot eOllHlnla InfQflTICt\{,n for v;:>ur prtufuot. Sluts) of

## n.tNContaioot

.. fV tM ratcontents of 011 rf/taU conUirt4fs tor yool produot. 5. l..otadon 

### of**~~.** ndlcllte th4 IQCation ot thll U'II dlrGetlmu: for roorproduct. 6. M#nfHIf 

### In 

### wNfm'\A.l h afiHlfQ'-prOWc1 • tndlcated thlt !lwthmJprwuct lab&! it llI\tachlid to rat!JII COntmrwr. 

## • •••••#.'



# ... I, Cynthia L. Giles-Parker, Product Manager l 

## Fungicide-Herbicide Branch, Registration Division, Office of Preventio11 1 

## Pesticides and 

## Toxic Substances, U.S. Environmental Protection Agency. do hereby certify that the pesticide product listed below is currently 

## registered with this Agency under the Federal Insecticide, 

## Fungicide, and Rodenticide Act, as amended, that the label attached 

## is a true, correct, and compared copy of the correspondence of record, and that the product may be sold and marketed in the United 

## States of America for the uses indicated on the label. The product registration listed below has been issued to:



## Rhone-Poulanc Ag Company P.O. Box 12014, 2 T.W. Alexander Drive 

## Research Triangle Park, North Carolina 27709 

## EE! Registration Name of Product
264-418**PRBP~Brand** 

## Plant 

## Regulator for Cotton

IN WITNESS WHEREOF I have hereunto set my hand and affixed the seal of 

## the u.S_" ENVIRONMEn PROTECTION AGENCY 

### this**~.;** 

### day of •.. A.D. 199$'



## Cynthia L. Giles-Parker Product Manager #22 

## Fungicide-Herbicide Branch Registration Division (750SC)



# 138

# .",. RHONE-POULENC**\<~_n~/** -?-..--- '" F:? 

## _"S=--

__ m

___**""~_~**______**~_'___:_**



### RHONE.POUlENC AG COMPANY

]anUilr}' 12, 1995


### Ms. Cynthia**Cile:;~Parker** 

### Ofiin:o(Pt'sticide

### Progrnms (H7S05C) 

### DO(llment Processing Desk (CERT) 

# us. EnvioJIUY\entai Proi('cnon Agency**l~oom** 

### 266A, Crystal Mal12 192! 

### Jefi{'u>on lJavisl-lighway Adington,Virginii1 22202



### iJ('ar ylr Giles-f',)rkpr: ....**~--------**



### I{e: I"R£p1'\1 br<Jlld Plant Regtlintor for**Cott~)~l, EI~:~** **R~·.!i'** 

### No.: 

### 164-418

--

# ..--
PJca:-;e prot'idcu$)vlth three (3) certific.Hcs Df

### registration for the include Lilt' fo!Jo\{:ing inforrnntion on each certificate: '- 1) Rt'gistran!: 

### -1thnlle-PlJulencAg Co.mpauy**_~**

### __ 

## p.n Box 12014, 2T. W. Alexander Drive 

### Research Trjallgle l'ilrk, NnrthCaroJinn 27709 Please**~) 1\:J.nl!~**  

## oi**thr~** 

### Ptnduct: PREpl'-1 brand PlvntRCh'1.:tlator for Cotton, 

### EPA Reg. Nn.: 264-418



### "

...lhatthe product l)Hy

### be sold and m<1rketed III the 

### Unitl..>d States

### for the 

### uses 

### inilicaled on the

### lab"I." )


### P!,..,.I&'" c(lllt,l('t

### nw ilt 

### i919)5,19-2112

### ShllUld .n)'1 

### h;)ve**;;r)~**.. 

### q\ll'slions.



### "

. 

# , , //L.,L/A--; L,i·,**</HddL(~** ',,-, 

### }lIdith L**rv~oon)** Rcgistratlllil ))oclJlnept5 

### SP('t'i,1Ust

0'0**e~)f** ',2UQ ? rN ".I EiA:,')'PPi' '. ""**"[SfA"'CMTR'A'~G,tr.""1<** riC ::' "l ;;:119', SMi-1D'v'0 INTtJlI,ATI0ML If"Lxf,UiGcn**~?)j**VI'**,N/',','LI'C'.:,~I'** .',1< Fl"**'l;1fR~'Af:i)Hr,i** iCls-rwl' "(j>-i',C"\!'

### >," fF

_ 'c' ;'j' In!'i,:'**~',l");'** /,>j'.'/,\,**Cd-!~", f,,~i**  (/. 

### •••• 

## • •



## •••• • • 

## •••••• 

## • • 

# • • •••••• 

## • ••• • 

# • • •••••• 

# . " 

## • 

## • •••••• 

# • •

" •• •••••



## • •• 

## •• •



## •••• • ••• 

# · " 

## •• • 

## • • •••••**rXC".','~0(;:;3,'11** Pf'.'7()"7'?n, d 

# 139

# ~**~HONE-POULENC**



# • RHONE.POULENC AG COMPANY


## ETH94-20


## November 8,1994
U. S. Environmental Protection Agency OfficeofPesticideProgram Document Processing Desk Room 266 A,CrystalMall No.2 1921 

## JeffersonDavisHighway Arlington, Virginia 22202 

## Attention: Ms. Cynthia Giles-Parker Product

## Manager (22) 

## FungicideHerbicideBranch 

## Registration Division (H7505C)

Dear Ms. Parker:


## RE: PREP®Brand Ethephonfor use on Cotton and Tobacco EPA Reg. 

## No. 264-418 .", 

### " ",



## Based upon your November8,1994 acceptance we aresubmitting onecopy'offinal labeling for 

## PHEP@ Brand Ethephon for useon Cotton andTobacco. We really appreciateyourfast 

## approval. 

# • Sincerely, 

# h;': ..<, "/, ,"/[/&:;';4,. '"

## //f!;~.~,~ WarrcnA. Davis Sen-ior Registration Mm)ager

f'JB()f lX!H ') iN**AUV,~.,::Cf1'.Jf1-.'~ I1SS~NiC1'**  WiA',(;L':: PMh, '1 (: :'l!:') ,'}',<}"S4\j':-iX(l**1"TU<'H·.110'-IA~ ;~l~X** **~i'.Jli31I1·)),f'l}'D i'~;c",f.Rt.FL'-;**  t,'"'C >,-P**'N;fi"N1\~I:)NM ~"srr';lni**  ,f,O'.\fy,\,,(:F<; F, h:/,i**.YU~" ~'J4~",:'**  LhSV}f>;[;Y'" t.pe**U~** 

## • 

## • •••••• • • • 

## •••••• • • •••••• 

## • 

## •• • •


## • •• 

# . , 

# . •••• • 

## • •• •• •

••••



## •••• •••••• 

## • 

## •

•• 

## ••••• 

## • • •••••**L\ce;.'o'·'f~;P** 

### F'ortc-r:'Gncf'- P,'de ,'n Ach,c,-prnen! 

# 140

# l 1Z,'IT fiEVlE',tED 

## If'!.**!hoo't,~'?Jj(;(j** 

## v.\-c;,**~t.** 

## }t:ti0«**82-~2.1** 

### tl".1.0ix1 "71 

### Dt-tlft 

## LataliLg [rb.tod / /

_ 

# if

- '7

# f 

# PREP TM

# BRAND ETHEPHON FOR COnON AND TOBACCO
For Commercial Use Or Agricultural Use Only_ Not For Rasldential Use ACTIVE INGREDIENT: Elhephon 12·Chloroelhyl) phosphonic acid-

........................................................55.4% INERT INGREDIENTS:

...........................................................................................................................44.6% 

### 'This eroduct conlains 

### 6 !?Ounds ethephon 

### per gallon. 

### EPA Reg. No. 264-418 EPA eat. No. 264-PA-Ol 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entioncio Isetiquota. busquo a alguien para quo so la oxplique a usled en detalle. (If

### you do 

### not understandthe label.find oomoone to explain 

### it

### to you indotall.) 

### For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 

### 1-SQO-334-7sn For PROPUCI

## l!lIll. InformatIon Call 1-800-334-9745 The use of this product for a varioty 

### of plant growth regulation uses aro protected by United Stales and toreign patents including U.S. Patents 38,791,188 and4,240,819. No license 

### Is grantod to use this product 10 countries otherthan the United States orfor any _te not contemplatad by this label. liability for paten! inlringoment may result from use or sale of this product outside tho Unitod tatos. 

# STATEMENT OF PRACTICAL TREATMENT
IF IN EYES: Hold eyelids open and trush with a gentle stream 01 waterfor at least 15 minutos. Get medical atlontion, prelerably an ophthalmologist. IF ON SKIN: Immediately wash skin with plenty of soap and water. IFSWALLOWED: Do not inducevomiting, Promptly drink a large quanlfty ot milk. O9g whites, gelatin solution or if these are not avallable, drlnk largo quantities 

### ofwater, A\IOld alcohol. Call II physician immadiat&ly. IF INHALED: Remove

...ictlm to fresh air. II not breathing. give artificial respiralion. Administer oxygen if nacessary. Get medical attention. 

# PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS COAAOSJVE. Causes ayo and skin damage. May

### befatal if

### absorbed through skin. Harmful 

### if swallowed or inhalod. Avoid breathing**~y** mist. Do not got in eyes, on skin oron clothIng. Koop away lrom domestic animals. 

### WOTE TO PHYSICIAN There is no specific anlidote. Alltreatmentshouki

### bo basod on observed signs and symptoms ofdistress in the patient. Overoxposure to materIals other than this product 

### may have occurrad. Victims 01 severe overexposure. by inhalation, should 

### be kept under modical obsorvation for up to 72 hours lor delayed onset 01 pulmonary edoma. In a victim 01 over·exposure by ingostkln. carelul gastric lavago Is required due to tho possibllily 01 stomach or esophageal perforation. This material is an acid. but use 01 alkaline substances to noutralize it is conlraindicated. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Applicators and other handlers must we3I coveralls over short-sleeved shirts and shor1 pants. waterprool glo

...e5. cnemlcal·resistant footwear plus socks, protective eyowear, chemical-rosistant headgoar for overhead exposure and chemical-resistant apron when cleanIng equipment or mixing and loading. : ••••• Discard clothing and other absorbod mate(mls that have boen dronchod or hea

...·dy contaminatod with this**prod~~ntrato.** Do not reuse them. Follow manulacturer's Instructionsfor cleaning/maintainIng PPE. It no such instroctions torwashables. use detergent and hot water. K04P and wash PPEsaparalo/yfromotherlaundry. • : •• :.: When handlSfS use clos&d syslems, endosod cabs, oraircraft in a mannerthat meets tho roquirementslrsted in tho Workor Pro'&c1ion· Standard (WPS) lor agricultural pesticides [40 CFR 170.240 (d) (4-6)), tho handler PPE requirements may

### be roclUcad or**mod~i\21·at!** specifIed in the WPS. : •••• •• 

## User Safety Recommendations Users should wash hands boloro oating, drinking, chewing gum, using tobacco or using the toilet. Remove clothing immediately if pesticide gols Insido. Then wash body thoroughly and pot on ciaanclothing, 

# ..... 

# . .... •


# . .. 

# ., 

# .

.....

•••• 

## •

# 141 •••••

# -_

..

# __

# ._._-

ENVIRONMENTAL HAZARDS Do not apply 

### directlyto water, or to areas where surface waler 

### is prosent or to inlertidru areas 

### balow [ho moan high water mark. 

### Do not 

### contaminato WaltH

### when disposing of equipmentwashwatora. 

### Do not contaminate water used for irrigation or domestic purposes. 

## USE PRECAUTIONS Do not 

### apply PREprw 

### bi'and Ethophon through any type of irrigation system. Avoid $pray drift to nearby crops tiS this product 

### willcaUSG modifications in plant growth. Plant Injury or reduood yialds 

### will rosult. 

### Do not plant anolharcrop within 30 days after rroatment. Mix 

### onlytho amount ofspray you expect to use each day. 00 not allow mixed solution to stand 

### overnight 

# DIRECTIONS FOR USE It 

### ! •• violation of Federal law to US8 this product In • RUlnn.r Inconslatont with 

### fl. lab.llng. Read entlr. labe' before using this product. 

### Do not 

### apply this product in a Vitt( [hat 

### will contact WOtXors or other persons,**o~hor** dlrOClly or Ihrough drift Only protected handlers may be In Iho aroa during appflcation. For any requiroments specific to 

### your State or Tr'lbe, consult tho agency responsible for pctsticide regulations.

this product only in accordance with itslaboUng and with the Worker Protection Standard,

### 40CFR part 

### 170. This standard contains for the prolection of agricultural workers on farms, forosts, nurserios, and greenhouses, and handlers 01 agricultural 

### It contains requirements for training. deconlamination. notification, and emergency assislanco. 

### ft also contains specific and eXC4Iptions pertaining to the statements on this labol about parsonal protoctlve equipment (PPE). nolilication to and restricted-entry intervals. The requirements in this box only apply 

### to uses 01 this product that are covered 

### by the Worker Protection Standard. 

### 00 oot entarorallow worner ontry Into treated areas durlllg the restrlctod-ontry inlerval (REI) of

### 48 hoUrs. required for early entry 

### to treatOO areas that 

### is permitted under the Worker Prolection Standard and Ihat involves 

### contact 

# I**~:::~~~if.~th~:a:\t, ~h:a,S~tb&on**  troatod such 

### as plants, 

### soil orwater Is coveralls over short-sleeved shirt and short pants, waterprool gloves. 

# I' footwear plus 

### socks, protective oyowearand chemical-resistant hGadgear for overhead exposuro. workers of them



### STORAGE 

## Do not contaminate water, 

### food, orfood 

### by storage or disposal. 

### II container 

### Is broken or contenls have spilled. lollow aU precautions indicated above and dean up Immediatoly. Bofore cIoaning on full I&npth trousers, long sieovOO shirt, protoctivo gloves, and goggles or face shield. 

### Soak upspill wi1h absorbent media sand, earth orother suitable malerial and dispose ofwaste 

### at an approved wasto dJsposal laciflty. DISPOSAL Pesticide wastes are acutely hltlardou$. Impropor disposal of excess pasticide, spray mixtUre, or rinsate is a violation of Federal law. 

### If these wastos cannot 

### be disposed of 

### by usa according to label insrructions, contact your State Pesticide or Environmental**C~,"I""tf** Agency or the Hazardous Waste represenlative at the nearest EPA Regional Office for guidance. 

### CONTAINER DISPOSAL Triple rins8 (or equivalent) the empty containers. Then offer lor recycling or reconditioning, or punctum and dispose 01 in a sanitary landlill, or

### by incineration or

### if allowed bystate and local authorities. by burning. II container is burned, 

### stay out 

### of smoke. 

### RETURNABLE**~-** 

### REFILLABLE CONTAINERS



## GENERAL INFORMATION • 

## •• 

# .' 

# . •••• •• 

# ••••• 

## • COTTON ••••• A foliar spray of PREPn.. brand Ethephon 

### wiU accelerate opening of malure unopened cotton bolls and enhanco

### dffo/raT~n which can result In oatUar harvest with an increased recoverable yiold. PREpm brand Ethephon treatment on cotton allows increased efficiency lrom a once-OVer harvest. : ••• 

## •••• 

# 142TOBACCO (FLUe-CURED): A loliar spray of PREPTlI brand Ethophon promotes oarly, uniform "yellowing- 01 mature tobacco. 

### PREP"" 

### roduco! curing Umo, allowIng more 

### offlCiont use 

### of ctJdng barn spaco, and incroasod control ovor harvost schedulos. 

### SPRAY PREPARATION Add 112 10 314 

### oftho required amount ofwater

### to tho spray tank. Start agitation. Add the raquired amount 01 

### PREP1')ol brand Ethophon, and tho remaInIng amount of water.**Prepar~** only as much spray solutton as can be usGd on the day 

### of mixing. 00 nol allow spray 

### solution to $landovemight. 

### Do not spill the conconlratod product on spray equipment. orany altplano parts. 

### ANYSPILlS SHOULD BE RINSED IMMEDIATELYWITH PLENTYOFWATER Use 01 a nurse tank 

### is highly rocommondod loravoIding posslblo spitts 01 coneontratod lormulation on spray equipment or any airplano 

### paris. 

### TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES PREPTM brand Ethephon is 

### compatibfe**w~h** 

### DEF1, FOLEX., Droppl, Harvade3• 

### Mathyl Parathion, Guthion l

, 

### and Matathion4• 

### PAEp'N may 

### be applied In sequonce or as a lank mixture {DO NOT TANK MIX WITH DEStCCANTS IF COTTON IS TO BE SPINDLE HARVESTED}, Follow all applicable uso 

### procaotklns and rato por acro recommendations on labols 

### 01 products applied as lank mixtures or In sequonce with PREP 1M 

### brand Ethephon. In samo cases slight reduction in boll opening rosponse has boen observed when tank mixos with dolotlants were used. Good 

### agitation 

### in tho spray tank is 

### essential and a tank mixture should not bo 

### allowed to stand without agitation tor moro than 5 to 

### 10 

### minot.s. Read and observo

### aJJ appropriate Iabol use directions and procautions for tho defoliants and insocticid&S usod. 

### NOTE: UndGfcertain conditions, tank mixtures 

### 01 PREpn.! brand Ethephon with desiccants containIng 

### sodium chlorate could rosuk in Ihe lormation 

### of hypochlorous 

### acidswhk:h on hoating witt omit toxicchlortde lumes. 

### EQUIPMENT CLEANING

• causa 

### 01 tho acidic naluro 

### 01 this product, prolonged oxposuro to spray doposit witt damago acrylic plastics. cortain paints. and otals. Rinse thoroughly with a detorgont and water all exposod acrylic plastic-typo materials (e.g.• aircraft wlndshilllds). and painled surfaces wlthln an hour attor expo$uro to spray doposits. At 1he ond of ollCh day, rloso thoroughly with a dotorgent and wator all the motal parts of tho aircraft and the associated spray oquipment exposed 

### to tho spray deposits.



## • 

## • •••••• 

## • • 

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# . 

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## • •••••

## COTTON

EXPECTED PREP'fId 

### ONE SPRAY VOLUME 

### APPLICATION USE CONDITtONS RATE 

### GALLON (Gala/A) 

### TIMING

Plnl./A

# ILBS A.!. Ac<•• AIr·· PREprw 

### Hot and 

### dry 8O&J= 

### or I 113 

### 1.0 6 Apply whon the

### ~.~; 

### Boll Openor· higher 

### maturo**,_~Us.,** 

### Dry and 

### 75 to

### sooF 2 1.5 4 15 -50 

### 2·5 I 10 I!'.


# , . Cool 

### but above**65~F** 

### 22/3 2.0 3 I•• t 

## 01. 'bo, I 

### Treatment**";~~rr:r~ns** 

## 0' bolls 710 14 days 

## in.**~",** 

## PREFN + 

### High soil moistUre tl3 0.25 

### 2' 15-SO 5-10 

### I

## ~~p_~_to 7 days prior to 

## FOLEX· 0' boll opening 

### O.tollant Tank 

### High fertility lovol To 

### be used as



### MIx

# ~ot**~ pl~.?,**  with. 

## 0, boll Rank ootton Oropp2 High soil moisturo 

### 1/3 0.25 

### 2' 10 ·50 3- 10 

### Apply 4 to 7 days prior to OofoHant Tank 

### High 1ertility Iovel PREpn.! 

### boll oponlng 

### Mix Rank cotton application. To be uSed as 

### a

### S~~;~lrGatmenl with, nolln of 

### PREpm boll


### Pr.·CondIUoner Hot, dry, 

### 2/3 O.S 

### 12 Appry 4 to 

### 7 days prior 

### to 

### for 

### Defoliation 

### Cool, above**65~F** 

### I 1/3 

### 1.0 6 15-SO 

### 2·5 defolianl. Enhancos,!oP 

## 0, crop dotoliallon datorioration 01 bottom

### c~ Rank cotton and alloWS tor II


### ·Pretreatment WHh DefollanfS Prior to PREpTM Boll Opening Treatment Ifthe cotton 15 overly rank or laying down in the mlddl••and good spray coverage ot tho bolls with PREpI'M is 

### difficult, a pretreatment wilh defoliants will 

### be usofullC improve boll coverago with PREpnc. Use dosage rates of PREPni brand Ethepilon recommended fOf bon 

### openlng. Road and observe an appropriate label use dlroclions and precautions for the defoliant used. "In California and Arizona use a volume of no tass than 5 gallons per aero for aerial applications. 

### !!aIofl Maturity "'boU

### is mature when

## ~ is 100 hardto 

### be dented when SQuGezed between thumb and lingers, too hard to 

### be sliced with asharp knife, and whon tho sood coat becomes light brown in color. 

### Use Limitations Do not exceed a maximum of2.0 lb. aYAtor combinad uses at PREpnt pGracre peryear. Boll Opening: 

### 00 not tank mix PREpm brand Elhephon 

### with adesiccant if

### the cotton 

### isto be 

### spindle harvested. Pre.condltion for Detollation: Do not tank mix PREpn.! with desIccants unless plant desiccation 

### is required. 

### Do not use a detollant before there is sufticienl mature unopened bolls to produco tile desired yiotd {soe Generat Intormation saction on how to test for

### bot! maturity. WHEN TO HARVEST COTTON 

## • 

## • •••••• • 00 not harvast cotton soonorthan 7 days after atreatmont with PREpnt brand Ethephon. • _ absOlVethe treated crop and harvestwhen optimum boll oponing has boon roached. Too early harvest might reduC&

# iliOfull advantage of tho treatmenl and too late a harvest may result in reduced quality and loss at Um which will drop ttom the plant. • : ••:.:



## • •• 

## •• •

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• •• 

# •• •

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## •••• •**~**

# ...

144 • • •••••• 

## • •

•• ••••• • • •••••

### PREPnI 

### Crop Situation Plnta/Aer.

Oirocted Spray t t/3 Application

OVer-Tho.Top 11/3-2213 Application



### USE LIMITATIONS Ac," 

### 50·50 

# fOBAeeo (Flue-Cured Only)

Spocfffc Dlrecltons



### Iwith 20% ;

. Treat only WhEIn leaves remainIng on the stalk are mature. To ensure remaining leaves are mature, tost spray several tobacco**Plan~**...**~~** doscribed under the section "ProperTime ofTreatment.· Use the lower**'~'**... In a normally mature crop whon experience indicatesthat m'lnimum i inducement 

### is required. Usethe higher rate when the 

### crop is 

### heavy and has 

### a tendency to be more rank or when temperatures are lower than normal. Always test spray to detorminG 

### if the tobacco Is mature enough to respond to treatmont with PREp-!'!oI brand Ethephoo. 

### Apply over·the-top PAEprw brand Ethephon spray 

### as a tine mist usingthree nozzles (one nozzle tips over the center ottho plant, and one

### o~**~~~_'~~d~** so all loaves are covered I slmilar to tho I pamml oi 

### osudw<oWol oo.nl$. 

# li,.. • of40 10 

### 50 cal

00 not 

### apply PAEpPt brand Ethephon to immature leaves 

### as thts can resuK tn unsatislaClory coloring, 

### weight loss and reduced leal quality. 

### 00 not aUowthe crop

### to over ripon in the lield alter using PREPN brand Ethophon. since this may cause some reduction in yield and qUality. 

### 00nottreat beforo anticipated major storm which could provent halVost and result in crop toss. 

### 00

### not apply PREPN brand Ethophon 

### if rain is expected within 

### 4- hours. 

### APPLICATION TIMING $uccossful results with PREpn.c call tor trGatment when leaves ar!) maturo, not overly rank green whon sprayed. To easily determine the proper treatment timIng 

### and the number

### of toaves perstalk raady for harvest, tost spray sGVerat plants In more than one location in aach 

### flold and obsoMil1hG response. Mature !tavos

### will begin

### to yellow in 24to 72 hours. Test loaves that fail 

### to yellow In 72l,lours are not malure and are not ready for PREpn! brand Ethephon treatment. Wait a few days to pormij lurther naturat maturing, then make another teS1 spray or-maturity· check.

CURING 

### PREp1l' TREATED 

### TOBACCO : •••:. Curing ptOCGdures aro as much an art as a scienC6 alld each cure must 

### b& ludgod on the basis 01 tobacco conditlbn, rnterval betWo&n treatment and harvest, weather and typo 01 curing lacility belore prescription temperature and ventilation scPledules c:!n"" establishod. To obtain maxImum quality, care must be taken to obsolVe and control the curing process closely, especially during thi!' tate -coloring- 

### and early *drytng" stages 01 1he lea/. •••••• 

# • • PAEpnt brand Ethephon treated tobacco will havo startOO the coloring process when harvested, reducing Ihetime**"~'"** in the •• coloring phase of curing. Tr08t&<:l tobacco should

### be driod taster. Htobacco leaves are groon or contain some greel'fwtfbn**harv'Ct)tI~** • 

### it may 

### be necessary 

### to color them lora lewhours. 

### Ifthe leavos are completely yellow, temperature 

### and ventilation mull

### be adjumM'" a manner

### to dry the tobacco asfas1 as possible wHhout scalding, Oncothe leaf 

### is dried 

### (314 dry), you should**tollo~rfm\I** procedures torcuring. Since PREP!")!: brand Ethephon treated leaves cure faster, treated and un1reatod leaves should not becUJIQiOolocgether in the same bam. • ••• 

## • •••• 

# 145

# LIMITED WARRANTY AND DISCLAIMER The manufaclurorwarrants (a) that Ihls

### product oonforms 10 tho chomical doscripUon on tho Jabol; (b) 

### that this product is reasonably lit lor tho purposes 

### Ht forth in the diroctions for us. when 

### It Is used in accordance with such directions: and (e) thallho directions, warning and olhor statements on this labol are based upon responsible experts' evaluation 

### of reasonable losts of oftoctivenO$$, 01 toxicity to laboratory animals and 

### to plants, and of residuas on lcod crops and upon reports offield experience. Tests have 

### not boon 

### made on all varktlios or In all states or underall conditions, lHE MANUFACTURER NEITHER MAKES NOR INTENDS, NOR DOES

# rr AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE, ANY OTHER WARRANTIES. EXPRESS OR IMPLIED, ANO IT EXPAESSlYEXClUDES AND DISCLAIMS ALlIMPUED WARRANTIES OF MERCHANT·ABILITYOR ATNESS FORAPARTICUlAR PURPOSE. THIS WARRANTY DOES NOT EXTEND TO. AND THE BUYER SHALL BE SOLELY RESPONSIBLE FOR, ANY AND ALL LOSS OR DAMAGE

### WHICH RESULTS FROM THE USE OF THtS PRODUCT IN ANY MANNER WHICH IS INCONSISTENT WITH THE LABEL DIRECTIONS, WARNINGS

### OR CAUTIONS. BUYER'S eXCLUSIVE AEMEDY AND MANUFACTURER'S OR SEUER'S ExcLUSIVE UABIUTY FOR ANY AND ALL CLAtMS, LOSSES. DAMAGES. 

### OR INJURIES RESULTING 

### FROM THE USE OR 

### HANDUNG OFTHlS PRODUCT, WHETHER 

### OR NOT 

### BASED IN CONTRACT, NEGLIGENCE. STRICT UABIU1Y IN TORTOROTHERWISE SHAlL BE UMITED. ATTHE MANUFACTURER'S OPTION, 

### 10REPlACEMENTOF. ORlHEREPAYMENTOF lHE PURCHASE PRICE FOR. lHEOUANTITYOF PRODUCT WI1H RESPECT 10 WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHALL MANUFACTURER OR SELLER BE LIABLE FOR SPECIAl, INDIRECT

### OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLINGOF THIS PRODUCT. NOTICE TO 

### BUYER Purchase of 

### this product does nol 

### confer any right$. under patients governing this 

### product or the use theroof in countries outsido of the United Statas

. 

# • 'DEF and Guthron ara registered traoomarkt ot Bayer AG, Germany. 2Dropp is 

### a registered trademark of 

### NOR·AM Chomlcat Company. 3HaNade is a rogistared trademark 

### 01 Uniroyal Company. "Malathioo 

### is atradomark of

### Amarican Cyanamid Company.

RhOno·Pouktnc

## ArJ Company P.O, Box 12014, 2T.W. Alexander Driva Research Triangle Park. North Carolina 27709 PREP is 

### the trademark 

### 01 RhOno·PoulQnc. FOLEX is 

### a registered trademark of 

### RhOno-Poulonc, PREPn.o brand Ethophon tor Colton and Tobaceo (MASTER) Approvoo 1tl3l94. 

## • 

## • •••••• • • • •••••• 

## • • •

## ••••• • •• • • 

# ·
.. •• •



## •••• • 

# ·

# .. ., 

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•••• • 

# •••• 

# 146 •••••• 

# • •



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## • 

# • •••••

# •

• Mr. Warren A. Davis Rhone-Poulenc Ag Company P.O. Box 12014, 2 T.W. Alexander Drive Research Triangle Park, Ne 27709 Dear Mr. Davis: Subject: Revised Tobacco Directions PREP Ethephon Cotton Boll Opener EPA Registration No, 264-418 Your Submission Dated October 24, 1994 

## The amendment referred to above, submitted 

## in connection with registration under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), as amended is acceptable provided that you submit one (1) copy of your final printed labeling before you 

## release the product for shipment. A stamped copy of the labeling is enclosed for your records.

Enclosure Sincerely yours,

Cynthia Giles-Parker product Manager (22) Fungicide Herbicide Branch Registration Division (7S05C)



# 147

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# 149

# •

• UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

# W-¥ll9':l'1JQI,j. D.C. 20<60



## WARREN A. DAVIS nIlONE-POULENC AG COMPANY P.O. BOX 12014 

## RESEARCH TRIANGLE PARK He 27709 orner-OJ" J'IlFV(tnlOtl,N;STICII)(S}'NO 

### roxlCsUBsrmcrs



## PRODUCT NAME: PREP BRAND ETHEPHON FOR COTTON 

## & TOBACCO 

## COMPANY NAME: RHONE-POULENC AG COMPANY OPP IDENTIFICATION NUMBER: 217786 

## EPA REGISTRATION NUMBER: 264-418 EPA RECEIPT DATE: 10/26/94 

## SUBJECT: RECEIPT OF AMENDMENT 

## DEAR REGISTRANT: The Office of Pesticide Programs has received your application for an amendment and it 

## has passed an administrative screen for completeness. During the initial screen we determined that the application qualifies for fast track review. The package will now be forwarded to the Product Manager for review to determine its acceptability. If you have any questions, please contact C. Giles-Parker, Product Manager 22, at**(703)-305-5540~**



## sincerely,



# . /. L:;,.a:.,J Front

# Eh~ ;rocessing Staff**-cJ'~~Information** 

## Services Branch Program Management and Support DivisionPh $11 rd'la t • 

# &EPA United S1111;tS 

## Environmental Protoction Agency W3!1'hlngton, DC 2.0400

# ~'I Registration IXX Amendment Other Application for 

## Pesticide**~** 

## Section I OI'P Identifier Numbu 

# 217186

1 Compllny!product Number 

# l2. EPA ProductMllmlQllr 13. Proposed Closliifh::artlon

# -4.-C-()~lP"-'-YI-P,-"'-"~e~~(-N-""'-)_264-418 ._- .TO.b

..

# ~-£-c_o-...

# -~-_I.; ?_M' C,

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# rke~r ___ 

# .1**~**

# ",,' 0 R"tri"", 

## PREP br.and Ethephon fo,_Cotton &

_ .... _ ....... _ . .. 5. Nome liM Addrosft ot Apptictlrlt 'lnc/udo ZiP Code} 

# Rhone-Poulenc Ag Company 16< Expedited Reveiw. In accordance 

### with RFRA SeClion 3(c)(3) 

## I(hHi). 

### my product is similar or identical 

### in composition 

### and labell'ng 

## P.O. Box 12014 

## 2 TW Alexander Drive 

# Research Triangle Park, NC 27709 

# o ChltCk ifthis is 

### a mtwifddrtlss !

### to: 

# !EPA Reo. No.

___ .___•..

__ .___. __ 

# !Product Name 

## Section· II

Amendmenl· Exploin below. Final printedtllbd. in repsonllo 10 Agencyhl\tor dat1id -.-.---- ----_

## I "Me**Too~** Application.
0lhn· Explain bmow. 

# -_
......

## ------_.-**E)(~anation;** UBf,I {I(jdftlonru pll{IelBI if n<lO(l$Bl'lry. IFor section 

### land S.c\ion 

### 11.1 

# Improvement in timing for harvest of treated tobacco. Recommendation to harvest all yellow leaves before treatment.

Section

. III



## Section· IV**.-~.-**



## • • t,**COn1rI~~tm:~t fComplf):'~**  lrflm!Fdireclly btlowfer fdM(iffc4tkm of**inrJiyJ~~sl** ro be**con~cttxf,** if(ulce5!iJ.fY. to pmc/W 

### WI:**~tt:,)** Name TIll" Tolophono NtP.f{lt\tludo ArCH) Code} 

# Warren 

# A. Davis Senior Registration Manager 919-549-2i79 •••••• 

## • • •



# .._'---

.....**~~ --~.**  

### -----"--- 

# .. . -

# . .**~.** 

# ! e:**D~bApPlioa._** ••• 

### 1 a..4IIvcd ••••



# • •• Certification I (;ortffy lhatlhcllllJtomonllll hove made 

### on lhis torm and ollattpchmonlt; thOl0to ate true, aceUlale and c9fTlP!lIle, I ocknowtlKfoe thai anyknowlinglly talM ormii!l!&3dlna $lllt&rMnt may be pI.mi$hOOle by tine or imprisonment or both Undol spp!icebltlillw. 

## •• lS1amJHM>:"• • 

## •••••

# '~~**j/J~-**.. -u-

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## WarrenA.Davis 

# I/O!;;"'I/'1'/ 

# I

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# c:: 1 Whit•• EPA FlIto Copy {orlglnall Yellow. Apt)/ieantCopy

# -------**~ ~n2M**  

## ACT IQI!CE: fth{le

### ~tf~**~** 

### fur thb. COHbCtiQ) of InfO(i!il!l!tttn it -%timtw t-tl**~** $.U5 fwur !WI"**r~,** imtodif$ -rfu jeff rwltt4if'CII {m;trutt'iitM",**~h'!G** udnil"El dliIJu 000n:;1.I$,**~lrlS** W'ri mtl>lf1tainlt'lG the oo!a**~,** :Md c;'lWpleHng**~** 

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### >'n1 to the Offlcwof Inf(}N1t!ltion 

### I!fld I!eaututory Affltitt!. OfHu ,/{If lila G It 

### and,**~~** Irlwrhlngtan. DC 

### 2C'ro3. 

## IHsnwtTlfmS: This 10m \s to be tilled fer all 

### iwlicctitmlS for,.., t1!gfstratim. end we rei"¢\listftltlon,**~t.** rd1Jl;:aiacion. to applicatlMII- for Mtifictlticm., finellX'intM tl)lbdfJ!!&" nn'lQlf>trJltfon, !ltc. In Ct'W te pf"¢CaM: un epplleatfen 'for III MY r-egistratjon 

### stAaritted en this 

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### i'oltll!!lrinu _tertal lI'Ult**~** tfwt applicadon: 1. Certification with Resp«t to Cft.at:foo 

### ot**~** (@'A f«m 1i57&-29). IIf I'I6t ueapt:ed by 40 ern 152.81 (b) (4)1; 2. Confidential**Stat~t** (of f«YSJta (EPA FtA"1It**~);** 3. 

### For.datar':**E>;~t(lfl** StatC'lCCnt (fAA roni**~mf** 4. five: ceplu of draft 

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## a.5 j[ 11 incll pape1' or a IIIDcltt.p of the**~ l~L**  

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## SECTIOH l

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# 152

# (Y

# ~ RHON"E-POULENC ::: :r:

RHONE-POUlENC AG COMPANY



## ETH94-17
October24, 1994
U S, Environmental ProtectionAgency Office ofPesticide Program Document ProcessingDesk Room 266 A,CrystalMall No.2 1921 Jefferson Davis Highway Arlington, Virginia 22202 

## Attention: Ms. Cynthia Giles-Parker Product Manager (22) FungicideHerbicide Branch 

# e Registration Division (H7505C)

OeM Ms. 

## Pnrker:


## RE: PREP@ Brand Ethephon for use onCotton and Tobacco EPA Reg. No. 264-418
Thissubmission contains ,,111 

## amended label for PREP® Brand Ethephon that include a 

## modification ofthewording forlIse

## on tobacco to emphasize theneed toharvest any leaves that havestarted to yellowbeforethe application ofethephon. Ifleavesbegintoyellow naturallyand arc then treated 'with ethephon overmaturity may result. In

## addition we havemade the label easier to read identifyingwhen to use highrates and when to use lowerrates. vVe 

## recommend the t!se ofthehigherrateonlywhen temperatures are cool (65F orless). In all othercases the low(>rrate should be used. A48 hourharvestinterval is 

## recommended to beconsistent with theworkerprotectionreentry inten'a1.
Based upon ourconversationonOctober24,1994 there shouldbe no need for anoffer to paydata compensation for thh::i submission as nonew data are necessary and no new uses arebeingproposed. The amended paragraph relating to the usc on tobacco hasbeen darkened in the label copy submitted to facilitate yourreview. • 

## • •••••• 

## • 

## \-Ye 

## \'vould appreciateyourpromptattention to this 

## label amendment to allow**P!~jlt~g** 

## of labels for the 1995 use season. Thanks for yourhelp. •••• Sincerely, 

# /// ,I· I

. t.//Q:<.u," 

# 1;.**/vfu",,~** 

## Warren A 

## Davis Senior gcgistration Manager

"0R(,X**'~'01~** J! ,','**M!oNV,:;~** flU!· '."- ,'JCSEARCHTR'ANCIFPAfI!c I,C :;;'II ','1",j', :'!'f'2'"J.lC n<TERh:;\TICliA(.**!~.P: k;"jS~11**  ,18'1-3);'; f<'U,',L :{i'lA(>, t"'G**~"f'** 'I,'[t;fd;:-IONAL ::is'!'i;!'i,**l'~lI"** 'x-rf:**n_~; ~,:,** **;-~** t,,-v(,!.:(; .110)],.'**i""''';LH.':"~-'_ A~<:**  I.:;; 

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# 153..**-.------~"** 

# -

BRAND ETHEPHON FOR COTTON AND TOBACCO

For Commercial Use Or Agricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: Elhephon (2·Chloroelhyl) phosphonic acid'

............"

...... H

................... , , ••

### 55.4% 

### INERT INGREDIENTS,

.... ...................................... .... ....... .............. . .................................44.6% 

### 'This product contains 6 poundS elhephon per gallon. EPA Reg. No. 264-418 EPA Est. No. 264·PA-01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

51 

### ustoo no &ntiondola 0l!qOOt3. busquQ a alguien para quo sa la axpliquQ a ustGd on dotallo. (11 

### you do not undorstand 1ho labol, lind SlJmoono to oxplain it to you in datail.) 

### For MEDICAL And TRANSPORTATION 

### Emergencies ONLY call 24 Hours A 

### Day 1-800-334-7577 For I 1-80().334-9745

# Tjru~'~.~:[j~~[':~~~fit'! U$O$ 

### i U.S. Patan!s is granted to use 1his product in countries olhor than 1he or lor any uso not conlomplatod by this liability for palon! inlringemant may result lrom use Or sale 01 this produCl outside Ihe United Slates

. 

# • STATEMENT OF PRACTICAL TREATMENT
IF IN EYES: Hold eyelids open and Ilush with 

### a genlle stream 01 water lorat leasl 15 minutes. Gel modlcal atfention, prolerably an ophthalmologisl. IF ON SKIN: Immediately wash skin with phlnty of soap and water. IFSWALLOWED: Do not indlJCo vomiting. Promptly drink 

### a largo quanllty 01 milk. 

### egg whftes, golalfn solution or 

### if thoso are not available. drink largo quantities 01 wator. Avoid alcohol. Call 

### a physician immediately. IF INHALED: Remove victim to fresh air. 11 not breathing, give artindal respiration. Adminisler oxygen il nocossary. Get mooical al1onllon. 

# PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS CORROSIVE. Causos eye and skin damage. 

### May be fatal 

### if absorbed through skin. Harmfut 

### if swallowed or inhaled. Avoid breathing spray mist Do oot get in eyes. on skin or on clolhing. Keep away Iromdomestic animals. NOTE TO PHYSICIAN

. _nero is no

### s~ijic antidote. Alilrealmant should be basod on observed signs and symploms 01 distress in Ihe patienl. Overexposure

### ~o matorials othor than this product may have occurred. Victims 01 severe ovoro>:posure, by inhalation, should be kept under modical obsorvation for up to 72 houts lor dalayod OO$ot of pulmonary edoma. In a victim of ovor-exposuro by ingestion. careful gastric lavago is required duo to the possibility 01 stomach or osophageal perforation. This matorial is an add, but use 01 alkaline substances to neutralize 

### It is contraindicated. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Applicators and other handlers musl wear coveralls over shott-sleeved shirts and short pants, waterprool glovos, chemical-rosistant lootwear pIuS socks, protllCtivo eyewoar, chomical-rli$istanl headgear lor overhead o>:posure and**chemicat.~'gt** apron whon cleaning equipment or mixing and loading. • Discard clothing and other absorbod malerials that have bGon drenched or heavily contaminalod with Ihis prod.cts·Concentrate. 

### Do nol rouse thom. Follow manulaclurer's lnslructions for cleaning/mainlaining PPE. 

### II no such inSlructions lorwasha:t)ltts, use delerionl and 

### hot water. Koep andwash PPE soparalely lrom other laundry. • : ••••: 

## ••• • 

## • When handlers use closed systems, enclosed 

### cabs, or aircraft in 

### a manner thaI meets the requiremenls listed in**111tr\('1~ker** Prplftt1tPll Siandard (WPS) lor agricultural peslicida! [40 CFR 170.240 (d) (4-6)J, Iho handler PPE rGquiremenls may be rod!lff2 or mOOdlita at; specillod in tho WPS. • •• •• 

## ••• ••••• User Safety Recommendations Usors should wash hands belore oating, drinking, chawing gum, using tobacco or using Ihe loil91. Remove clolhing immodialely 

### if pesticide gols insido. Then wash body lhoroughly and pul on clean clolhing. 

# ... •• 

## •

••••

•••• • 

# 154 • •

# -------- ._-----

ENVIRONMENTAL HAZARDS 00 not apply diroctfy to walnr, orto areas whore surfacowater 1$ prosont or to intonidalaroas below the mean high wator mark. 

### Do no1 contaminato waterwhon distxlsingof oquipment washwators. 00 not contaminatowater used tor irrigation or domosl!c purposos, 

## USE PRECAUTIONS 00 not apply PREP'" brand Ethophon through anytyJX!' of irrigation systom. Avoid spray drift to nearby crops as this product

### will cause modilicatlOns in plant growth, Plant intury or reduced yields 

### will result. Do not plant another cropWithin 30 days afUH troatmGrlt Mix onlythe amount of spray you expSCI to use each day_ Do not allow mixed solution to stand ovornight. 

# DIRECTIONS FOR USE It 

### Is a violation of FedoTal tew to uae this product In a mannor Inconalstant with Its labeffng, 

### Road ontlr. label belore 

### 1.I0ln9 thlo product. Do not apply this product in a way that will contact workers or other pefS(lns, either directly or through drift. Only protected handktrs may bo in the aroa during application. For any requiroments spocilic 10 your State or Tribo, consull Iho**ag~ncy** responsiblo for postiddo rogulalions.



### US/il this product only in accordanco with its laboliflg and With tho Workor Prot&Ctlon Standard, 

### 40 CFR part 

### 170. This slandard contaJns lor the protection of agricultural worimts on larms, forests, nursorios, and groenhouses, and handlers of agricultural 

### It contains reqUIrements for training, doconlaml'nation. notilication, and emergency assistance. 

### It also contains tpocific I and o)(ceptions penalning to tho statoments on this labet about personat protective oquipment (PPE), notification to

and rostriclod-entry intervats. Tho requirements in this box only apply to uses 01 this product that are covered by tho Workor

Standard. Do not onter or allow worlmr ontry into troated areas during tho rostricted-Mtry intervat (REI) 01 

### 48 hours. PPE raquirad for earfy entry to troated areas that is pormltted undor tho Workor Protection Standard and that invotvos contact anylhing that has beon treatod such as plants, SO'lt or water is coveratls over short-steeved shirt and 

### short pants, waterproof 

### g<w".j c/lomical-rosistant footwoar plus socks. protective oyewoar and chomical-resistant headgear lor overhead exposure. 

### II ti t 

### II

STORAGE Do nOI contaminato water, food, orfead by storage ordisposal. 

### If container is broken or contents havo spiffoo. fotlow 

### all precautions indicated above and clean up immedialoly. Before cleaning up, on lull kingth trousors, long stooved shirl, protoctiv$lJloves. and gogglesor lace shletd. Soak up spill with absorbent media such as sand, earlh orother suitable materiat and dispose ofwaste at an approved waste disposal facility. DISPOSAL 

### >""iC;d, wastes are acutely hazardous. tmproper dieposal 01 excess pesticido, spray mixture, or rinsato is a violation 01 Fodoral law. cannot be dispos&d of by use llCCording to tabet instructions, contact your Stato Pesticido or Environmontal Control

## ~:;,,/.':~I'=h:OHazardous Wasto reprosontativo al tho noarest EPA Regionaf Oflice for guidanc4. DISPOSAL rinse (or equivalent) the empty containers, Then offer lor rocyclinlJ or reconditioning, or puncture and dispose of in a sanitary j

# "oa,,,,. orby incineration or if allowed by slato and local authoritios. by buming. 

### If container is burnod, stay out 

### of smoko.



### RETURNABLE**~~** 

### REFillABLE CONTAINERS • • After uso, return the container to tho point 01 purchase or dosignated locations. This container must only

### be rofiflMIwTth-PREPm brand Ethophon lor Cotton and Tobacco. DO NOT REUSE THE CONTAINER FOR 

### ANY OTHER PURPOSE. Prim "

.... efifllng, I""""t/ thoroughlY for damage such as cracks, punctureS, abrasions and damaged or worn out threads on closure

# dov""•••-00 not transport damaged or toaldng containers. Check lor leaks aftor refilling and before transportation. For inlormation

### Q"0j,,\'lh;:':.~:;:~l:n unused, unwanted product, contact RhOne-Poulonc at 

### 1-800-334-9745. For information on cfeanup ofspJfls, 

### 00""'''. R 

### '-800-334-7577. If the container is not 

## GENERAL INFORMATION COTTON 

# •••• • 

## ••

•• 

## • • 

## • •• •• 

## ••••• 

# • • •

## •••• A fotiar spray of PREPn< brand Ethophon will accolerato opening 01 mature unopened cotlon bolls and enhanca'l:W'ol!llJon which can result In earlior harvost with an increased rolcoverabte yield. PREpno brand Ethephon troatmont on cotton anows**i~"s&d** efficiency trom a once-over harvost. •• :. 

# 155TOBACCO (FLUE.CURED): A loliar spray 01 PREpm brand Elhophon promotes early, uniform 'yellowing" of mature tobacco. PAEpni roduces curing hme, altowing mora eUicienl use of curing barn spaco, and increaseO control ovor harvest schedules. SPRAY PREPARATION Add 

### 112 10 

### 314 01 Iho raqulred amount 01 water to the spray lank. Start agitation, Add tho roquirod amount 01 PREpTh! brand Ethophon, and the remaining amount of water. Prepare only as much spray solution as can be used on tha day 01 mixing. Do not allow spray wlutionto sland overnight. 

### Do not spill the concenlrated product on spray equipmont, or any airplane parts. ANY SPILLS SHOULD BE RINSED IMMEDIATElYWITH PLENlYOF WATER Use of 

### a nurso tank is highly recommondGd for avoiding poSSIble spills of concnntratod lormulation on spray equipment or any airplane parts. TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES**PREPll~** brand Ethephon 

### Is compatible with DEP,**FOLEX~,** Dropp2, Harvade3

. Mathyl Parathion, Guthionl, and Malalhion4• PREPN may be applied in sequonco or as a tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicablo use precaulions and rata por acre racommendations on labels of products appliod as tank mixlures or in sequenco WIth PREP no brand Elhephon. fn somo cases slight reduction in boll opening response has been obselVed whon tank mixes with defoliants were used. Good agitation in tho spray tank is essential and a tank mixture should nol be allowed 10 stand withoul agitalion for more than 5 to to minutes, Road and obsolVe all appropriato label use directions and precautions for the dolobants and insecticides usod. NOTE: Under curtain conditions, tank mixtures of PAEprn brand Ethephon with desiccanls conlaining sodium chlorate could I result In tha lormation of hypochlorous acids which on h0ating will emit loxlc chloride lumes" EQUIPMENT CLEANING Because of tho acidic nature 01 this product, prolonged exposutE.' 10 spray deposit will damage acrylic plaslics, cottain paints, and malals. _inse thoroughly wilh a dotergont and water all

# ~xposed acrylic plastic·typo materials (e.g

.. aircraft windshiakls), and painted surfaces within an hour alter exposuro to spray deposits. At the 

### Gnd of each day, rinso thoroughly with a dotorgonl and wator all the motal parts oj tho aircraft and Ihe associaled spray equipment exposod to tho spray depoSIts

.



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COTTON


## EXPECTED PREpru ONE'M SPRAY VOLUME APPLICATION 

### USE CONDITIONS 

### RATE (Gals/A) 

### TIMING 

# :: ';:' ILBS A.I. Acr•• Air" 

### PREpN 

### Hot and dry**80~F** or t 113 

### 1.0 6 Apply whon tho numoor 01 

### Bal! Opener' highor mature unoponod bolls is Dry and 75 to**80~F** 

### 2 1.5 4 

### 15 ·50 

### 2·5 sulficiont to produce thO' desired crop. Seo 

### below tor Coo! but above**65~F** 

### 22/3 2.0 3 tost 

### 01 

### boll maturity. Troatmont uniformly opens 

### or bolls 7 to 14 days earlier. 

### Aaok cotton**PREP~** + High SOil moisture 1.'3 0,25 

### 24 15 ·50 

### 5**~**

# to Apply 4 to 

### 7 days**prjo~** 

### to FOLEX3' 

### or PREp'N' boll opening Defoliant Tank High lortility level application. To be used.

# as MIx or 

### a**so~u~~~',**

### treatmont with, not in 

### 01 PREpm boll 

### Aank cotton I 

### PREprn. OtOpp2 High sod moisture 

### 113 0.25 

### 24 

### to·50 3·

### to Apply 4 to 7 days prior to 

### Tank High fertility lavel 

### PREpm bol!**op~ning** 

### MIx Rank cotton 

### application. 

### To be 

### usod as a sequential treatment with, not

### i~**pl~ce ~I**  PREpn4 boll**Pr.~Candftlon.r** Hot, dry, 213 

### 0.5 12 Apply 4 to 7 days**prior.~~** 

### lor OafoJfatton Cool, above 65Gf t 113 

### 1.0 6 t5-50 

### 2·5 defolianl. Enhances top


### or crop deloliation reducing ;;;.riOratkm 01 bottom crop Rank col1on allows for earlier


### ·Pretreatment With Defoliants Prior 10 PREprn Boll Opening Treatment If the cotton is overly rank or laying down in the mlddl•• and good spray coverage 01 tho bollswith PREPTJoI Is difficult, a pretreatment with defoliantswill be U$etul to Improve boll coverage with PREpni. Us.dosago rales of PREpTJoI brand Ethephon recommended for boll opening, Read and obsGrvo aU aPPropriale label use diroctions and precautions lortho d&ioliant usoo. "In California and Arizona use a volume of no los$ than 5 gallons poracre for aorial applications. 

### Boll Maturity**~** boll is maturowhen it is too hard to

### bo donted when squeezed ootween thumb and tingors, 100 hard 10 be s!icod with a-sharp knllo, and W'.hen the seed coat bocomos light brown in color. 

### Use Limitations 00 not O)(coed a maximum ot 2.0 lb. ailAtor combin!)d uses at**PAE~** poraero peryear. Boll Oponing: Do not tank mix PREpnI brand EthephOn with a desiccant 

### iftho col1on is to be spindle harvested. Pre-Condition tor Dofoliation: Do not tank mix PREP"" with desiccants unloss plant desiccation is required. Do not use a detoliant bofore there is sufficienf mature unoponed bolls to prodUC8 tho desired yield (soo Generallnformalion S&CI.ion on howto tost for boll maturity. WHEN TO HARVEST COTTON 

# , 

# . •••••• 

## , 00 not harvost ootton soonorthan 7 days after a treatmont with PREP"" brand Ethophon. • ••• 

# , , Observo the lrealed crop and harvest when optimum bon openIng has boan reached. Too early harvest might**rGdut''1~efull** advantaga of the treatment and too late a harvGsI may result in roducod quality and loss of lint which WIll drop from the plant.· : ••:.: 

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# /PREpTU ."P'.Y 

# f6BACCO (Flue-Cured Only)

Crop Situation Ptnts/Acro

## AC~~SI Spocitlc Olnctlons

Dirocted Spray I 1/3 

### 50 ·60 Usa drop nozzles. Choose TG or OC spray tips designed to apply 

### 50

. 60 Application gpa at 

### 35·40 psi and at tractor spoed 

### 01 2·3 mph. Uso 2 nonl"

## PO:::;llr:,~:i:;~'h .ido ollho 'ow d"'ppod low onaugh 10 dimel tho spray to I to be riponed and harvosted. Thorough**.~£'.~~~** . . a dirOC1od spray, 

### be sure to harvest all !wrth20%m i . Over-The-Top t 

### 113-2213 40-60 Troat only when leaves romaining on tho stalk are mature. To Applicarion romaining loaves aro maturo. tost spray sovernt tobacco plants as describGd undorthe section "Proper Time 

### 01 Treatment: Use the /ower rate in 

### a normally mature crop when oxporionco indicates that minimum**riP~n~~** inducement is r&quiroo. Use the higher rate whon the crop is hoavy and 

### a tondency to be more rank or whGn tomperaturos are lower than normal. Always test spray to delermino if the tobacco is mature onough to respond to treatmont with PRfPThI brand Ethophon. Apply ovaHhe·top PREpl"- brand Ethephon spray as afine mist using throo nOlzles (one nozzle tips over the cantor 

### 01 tho plant. and one on oach side)
so 

### all

## 1f}:a:~~~;~~I~~[~d similar to the Ii

## ~+60**:~~ern** 01

. Iaoonl,. tis.a I 40 10

. USE LIMtTATIONS

Do not apply PREpm brand Ethephon to immaturo leavos as rhis can result in unsatislactory coloring. waight loss and roduced loaf quality_ 

### 00 not allow tho crop to over ripen in the freld after using PREPrn brand Ethophon, since this may cause somo roduC1ion in yield and quality, 

### Do not treat boloro anticipatod major storm which could prevent halVest and result in crop loss. 

### 00 not apply PREP"" brand Ethophon 

### if rain is oxpoctod within 

### 4 hours. APPLICATION

# successful~,~O~,":~':";~o~:p.~~~;~~~;~:~;:~;~~}::;;~ are maturo, not overly rank groon when sprayed. To oaslly detormlne the proper harvest. test spray sovorol plants in morothan one location in / oach 

### field in 

### 24to 

### 72 hours, Test loavesthat fall to yotlow in 

### 72 hours aro not matUlo

### ;~iEih"Ph;'~·i,;.;t';';,otWait 

### a low days to permit lurther natural maturing, thon make another tost

CURING PREpm TREATED TOBACCO Curing procedures oro as much an art as a sao-nco and oach cur. must be 

### iudged on the basis of

## tObT~~;~.~~l~::,~:~~~:~E lreatmont and harvest, weathor and typo of curing facility boloro proscription temperatura and established. To obtain maximum quality, care must bo taken to obsolVo and conlroltho curing procoss I [ate ·coloring- and early "drying- stages oftho loaf. 

## • • PREprw: brand Ethophon treatod tobacco will have started tho 

### coloring procoss whon harvosted, reducIng the tim.fe"q1J1rad in tho •• coloring phaso of ClJring. Treatod tobacco should be dried lastor. 

### Iftobacro l6avos are 9roon or contain somGgreGn wlfon haMlMl. it may bo nocossary to colorthorn for

### a low hours. 

### If lhe leaves are complntoly yollow. tGmpora1ure and ventilation mtTsl 

### be adjMftltrln 

### a manner 

### to dry the tobacco 

### as fast 

### as possiblo without scalding. Once

### the leaf 

### is dried 

### (3/4 dry), you should folloJV**Qd~al** 

### procGdures tor curing. Sinco PREpl>! brand Ethophon treatod loaves cure tastor. tmatod and unlreated leaves should not be ctmtogethor in tho sarno bam. • ••• 

## • 

# .....158**~~~~-~-------~~~~~----~-~-~----**



# LIMITED WARRANTY AND DISCLAIMER ThQ manufacturor warrants (a) 

### that this 

### product conforms to tho chQmical doscrlption on tho labol; (b) that this prOduct is roasonably Iii lor tho purposos sot foJ1h in tho diroctions for use when 

### it is used in accordance with stroh directions; and 

### {el that tho directions, 

### warning and other statoments on this label are based upon rosponsibfo expons' evaluation 01 roasonabJQ tests 01 effectiveness, 01 toxicity to laboratory animals and to plants, and of rosiduos on food crops and upon roports of field 9XporiQOCO. Tests have not been made on all varieties or in all slmos or undQr aU condilions. THE MANUFACTURER NEITHER MAKES NOR INTENDS. NOR DOES IT AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE. ANY OTHER WARRANTIES, EXPRESS OR IMPLIED. AND IT 

### EXPRESSLY ExcLUDES AND DISCLAIMS All IMPLIED WARRANTIES OF MERCHANT·ABILITY OR FllNESS FOR A PARTICULAR PURPOSE. THIS WARRANTY DOES NOT EXTEND TO, AND THE BUYER SHALL BE SOLELY RESPONSIBLE FOR, ANY AND ALL LOSS OR DAMAGE WHICH RESULTS FROM THE USE OF THIS PRODUCT IN ANY MANNER WHICH IS INCONSISTENTWITH THE LABEL DIRECTIONS, WARNINGS 

### OR CAUTIONS, BUYER'S EXCLUSIVE REMEDY AND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY FOR 

### ANY AND ALL CLAIMS, LOSSES. DAMAGES, OR INJURIES RESULTING 

### fROM THE USE OR HANDLING OFTHIS PRODUCT, WHETHEROR NOT BASED IN CONTRACT. NEGLIGENCE. STRICT LiABILITY IN TORT OROTHERWISE SHALL BE LIMITED, ATTHE MANUFAClURER'S OPTION, TO REPLACEMENTQF, OR THE REPAYMENT OF THE PURCHASE PRICE FOR. THE QUANTITY

### OF PRODUCT

# wm; RESPECT TO WHICH DAMAGES ARE CLAIMED, IN NO EVENT SHALL MANUFACTURER OR SELLER BE LIABLE FOR SPECIAL, INDIRECTOR CONSEQUENTIAL DAMAGES RESULTING 

### FROM THE USE OR HANDLING

### Of

### lHlS PRODUCT. 

### NOnCE TO 

### BUYER Purchase 01 this product does not contor any rights undQr patients govQrning this product or tho use thoraof In countries outsido 01 tho Unilorl States.

elDEFand Guthion arGo rogistorod tradomarkS 01 Bayor AG. Germany, 7Droppis a registered Iradomark 

### ol NOR·AM Chomical Company. 3Harvado is a rogistfJrod trademark 01 Uniroyal Company. 4Malathion is a tradomark ofAmorican Cyanamid Company

.



# •

RhOno·Poulonc Ag Company P.O. Box 12014, 

### 2 TW. Alounder Drivo Res&arch Trianglo Park. Nol1h Carolina 27709 PREP is tho tradomark of Rh6no·Poulonc. FOLEX Is a registered trademark of 

### Rh6no·Poulenc. PREPIM brand Ethophon for Collon and Tobacco (PENDING) Submitted tOf_l94. 

## • • •••••• 

## ••••• 

## • •

•••• 

## •


# .. . •• • 

# ·
.. •••• 

## • 

# ••



# ., 

# .

• 

# ·
.. •• •

••••

•••• • •

## •••

# 159

# /

•

## ••••• 

## • • • • 

## • •

## •••••



## • •



# .. •

## ••••



## • 

## • •

## ••••

# '.



# •

• I!l!IIO!W!DU!!
SUBJECT:

FROM:

TO:

THROUGH: UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460



## OCT 24 1994

OFFICE Of PRE\I£NTION, PESTtCID£SAND TOXICSueSTANCES 

## Addendum to the ORES Analysis for the Ethephon Reregistration Eligibility Decision Document Stephen A. Schaible

# ~;;1~ Dietary Risk EValuation Section SAB/HEO (7509C) 

## Jane s. Smith Reregistration Section CCB/HEO 

## Elizabeth A. Doyle, Head ORES/SAB 

## Health Effects 

## Division (7509C) 

# L.q**.~**

# ..**.AI:t~/** (7S09C) 

# ty!l'-'
Percent of crop treated information supplied by BEAD in a L. Luben 

## memorandum to C. Lewis dated 12/13/91 was 

## inadvertently omitted from consideration at the time the ORES analysis for the RED was 

## performed; the analysis for the RED is described in a S. schaible memorandum to J. 

## Smith dated 10/11/94. More recent 

## information than that supplied in the Luben memo was incorporated into the RED analysis through a J. 

## Hogue memorandum to J. 

## Loranger dated 9/26/94, but refined estimates of percent of crop treated exist in the Luben memo for crops which are not included in the Hogue memo. The previously omitted percent of crop treated information was added to the ORES file for ethephon, and a chronic exposure analysis was performed. Because percent of crop treated information is not used in the ORES acute exposure analysis, and ethephon is considered a Group D carcinogen, only estimates of chronic, non-cancer exposure and risk are affected by the addition of this percent of crop treated information. The residue inputs and toxicologica1 endpoints to which chronic exposure is compared remain the same as those described in Schaible's 10/11/94 memo; please refer to that memo for discussion of assumptions which went into this analysis and for residues and toxicological endpoints. Where percent of crop treated estimates are given in both BEAD memos for a crop, the estimate in the Hogue memorandum was used, being the more recent. A summary of the residue and percent of crop treated information which was used for this analysis is attached as Table 1.

## ".



# •

• Results of ORES chronic analysis As was done before, two ORES chronic exposure analyses were performed, the first including uses recommended for revocation in 

## the Tolerance Reassessment Summary of the Residue Chemistry Chapter of the RED and the second excluding these uses. TMRC estimates described in the previous Schaible memo are not affected by this analysis, only ARC estimates changed. Summaries of the ARCs and their representations as percentages of the RfO are attached as Table 2 (including recommended revocations) and Table 3 (excluding recommended revocations). 

## The ARC for the U.S. population published tolerances only are considered is 0.001572 mg/kq b.wt/dayI 

## which represents 8.7% 

## of the 

## Rfo. When residues in poultry and eggs, the recommended increase in the tolerance on cottonseed, and the proposed tolerance for "apple juice" are: considered, the ARC is raised to 0.001624 rnq/kq bwt/day, or 9% of the RfO. The ARC for the subgroup most highly exposed, non-nursing infants less than one year old, is 0.008227 rnq/kq bwt/day (46% of the RfD) from published tolerances and**0~008781** 

## mg/kg bwt/day (49% of the RfD) from published, proposed and recommended uses. If published tolerances recommended for revocation are excluded, the ARC for the overall U.s. population from all uses recommended through reregistration (including poultry and eggs, the increased tolerance on cottonseed and the proposed tolerance for "apple juice ll ) 

## is 0.001553 mg/kg bwt/day, or**8~6%** 

## of the RfD. The ARC for non-nursing infants less than one year is 0.008427 mq/kq bwt/day, or 47% of the RfD. These risk estimates should replace the chronic estimates supplied in S. Schaible's 10/11/94 memorandum for use in the ethephon RED. The discussion in s. Schaible's 10/11/94 memo regarding th'e use of the ORES default of 100% crop treated for uses recommended for revocation where percent crop treated information was not available or was more than 5 years old is still applicable, though fewer crops are affected by this policy with the addition of the percent of crop treated information provided in Luben's 12/13/91 memo. Attachments

cc: ORES, PM 22, Caswell 

## # 42,6A



# 161l #426A CAS No. 16672-87-0 A.I. COOE: 099801 CrR No.

FOOD CooE ,000

01002AA 0100ZAA 0100211." b1009AA 01009AA 01G09M, 01009M 01010AA 01010

...... 01010M. 01010JA 01010JA '01014/1.A 01014M 01014M 0101401'1 010140/1. 0101401'1 01014JA 01014JA Ol014JA 02004AA 020(tJ,M 0200411.8 02004A9 02004"1'1 02004)111. 02004JA 02004JA 02004JA OZOO4JA 02oo7M 0200BAA 02008JA 03005AA 03005M .03005AA 03007M 03009AA 030G9M



## , 

# , BLACKBERRIES BlACIC8£RRIES BLACKBERRIES BWEBERRIES BLlJ£BERR1ES BLlJ£SERRIES BLUEBERRIES CRAMSERRIES CIWf8ERIUES CRAIfflERRIES CRANBERRY-JUICE**CRANBERRY~JUICE** GRAPES-FRESH GRAPES- FRESH GRAPES· FRESH GRAPES-RAISINS GRAPES·RAISINS GRAPES-RA1 SINS GRAPES-JUI CE GRAPES-JUI CE GRAPES-JUICE LEMOHS·UNSJ'EC L£MOHS-UNSPEC

- LEKOtIS'PUtP LEMONS-PUlP LEMONS-PEEL LEMONS·PEEL LEMONS-JUIcE LEOs,JUICE LEbS-JUICE LEMONS-JUICE TANGELOS TANGERINES TANGERINE'JUICE F1LBERTS FILSERTS fIlBERTS HACAOAMIA MlJTS WALNUTS

,WALNUTS 

# .............. /**-"~-**

### 1.~okw**12/:;11~1~;;** ."'. ."""/''<11',- 

## C. /..f...(W**~7A'A'lf_(n~~**

### TAl\l.~ 

# 1.
AtHICIPATEO RESIDlIE INFORMATION FOR CASW£LL MMBER 42M DATE: 10/14/94

LEL=

FOOD FORM

10 RAW'FRESlI OR NFS 21 Coot:::EO'IIFS

. 62 COOKED-FRESH 011: FROZEN-BAKED 10 RAW- FRESH OR MFS 21 COOKEO'NFS 22 COOKED-FRESH-SAXE!) 62 COOKEO-FRESH OR FROZEN'BAKED 10 RAW-FRESH OR NFS 21 cro;EO'NFS 31 COOKEO-FRESH OR CANNED 15 RAW- FRESH OR CANNED 31 CQOICED-FRESI/ OR CANNED 10 RAW' FRESH OR HFS 21 COOKEO·MFS 31 COOKED-FRES" OR CArtHED 10 RAW'FRESH OR NFS 21 C()(M(ED-NFS 22**COOKeO~FRESH-BAKEtl** 10 RAW-FRESH OR NFS 15 RAW' FRESH OR CANNED 21 COOIC£O-NFS 10 RAW-FRESH OR NFS 22 COOKEO-FRESH'SAKED 10 RAW' FRESH 011 NFS 31 COOKED-FRESH OR CANNE{) 10 RAW' FRESH Ill: NFS 21 COOI(El)-NFS 10 RAY-FRESH OR NFS 15 RAW· FRESH OR C,IINNEO 21 COO(£D-NFS 31 COOKED- FIIESH OR C,IINHEO 10 ItAW"FIU:SH OR IIFS 10 RAW-fRESH OR KFS 15 RAW-FRI;SH Ol! CAIfNEO 10 RAW-FRESH OR NFS .21 COOKEO-NFS 22**COOk:EO-~RESM-8AkEO** 10 RAW-FRESH 

### OR NFS 10 RAW'FRESH OR HFS 21**C~O.NFS** 

# • TOlERANCE AIITICIPATEO PET.f (ppm) RESIDUE. (FPII) AR STATISTIC T'fPE



# ,,,,.. 9E2262 

# ",

# ... 9£2262 9£2262 9£2262 9£2262 ". 3F1353 3F1353 3F1353 3F1353 3F1353 9F2118 9F2178 9F2178 9H5207 985207 9H5207 9F2178 9F2178 9F2178 9£2262 9E2262

..2262 

# ..,,., 91:2262 

# ""62 9£2262 

# ,.,

# ... 9£2,., 9£2262 

# ..,,., 9£2262 9£2262 3F1344**3F1~4** 3F1344 ""., 

### NO PET' NO P'ETt' P 30.00000

,. 30.00000 P 30.00000 P 20.00000 P 20.00000 P 20.00000 P 20.00000 P 5.000000 P 5.000000 P 5.000000 P 5.000000 P 5.000000 P 2.000000 P 2.000000 P 2.000000 P 12.00000 P 12.00000 P 12.00000 P 8.000000 P 8.000000 P 8.000000 P 2.000000 P 2.000000 P 2.ClOOOOO P 2.000000 P 2.000000 P 2.000000 P 2.0000c0 P 2.000000 P 2.000000

,. 2.000000 P 0.500000 P 0.500000 

### P 0.50000a P 0.5DOOOO P 0.500000 P 0.500000 P 0.500000 

### P 0.500000 P 0.500000 18.400000 7.360000 7.360000 8.540000 3.420000 3.420000 3.420000 0.350000 0.27OQ()0 0.270000 0.350000c 0.35000OC 0.350000 0.350000 0.350000 0.70oo00C 0.700iWIC 0.70000OC 0.370ool)C 0.37tlOOOc 0.37OOOOc 3.610040 3.61000Cl 0.410000 0.410000 3.610000 3.610000 0.150000C 0.1500ooc 0.15OO00c: 0.1500(JOC· 0.040000 0.040000 0.020000c 0.130000 0.130000 0.130000 0.005000 0.0300(I(I 0.030000

# • % CROP TREATEO

1.00 1.00

, .00 100.00 100.00 100,00 1(10.00

6.00 6.00 6.00 6.00 6.00 7.00 

### 7.00 7.00 7.00 

### 7.00 7.00 

### 7.00 7.00 1.00 100.00 100.00 100.00 100.00 100.00 

### 100.00 100.00 100.00 

### 100.00 100.00 100.00 100.00 100.00 54.00 54.00 54.00 54.00 11.00 

### 11.00 PAft¥::

R£S. VA!.U£ USED IN TAS fWM (PID)

0.184000 0.073600 0.073600 a.s40000 3.420000 3.420000 3.420000 0.021000 0.016200 0.016200 0.021000 0.021000 0:024500 0.024500 0.024500 0.049000 0.049Q00 0.049000 0.025900 0.025900 0.025900 3.610000 3.610000 0.410000 0.410000 3.610ll00 3.610000 0.150000 0.150000 0.15ooot1 0.150000 0.040000 0.040000 0.020000 0.070200 0.C170200 0.0702<lO 0.002700 0.003300 0.003300ANTiCIPATEO IlESIOIJE**1IfF~TlON** FOR CAMll IMtSI:R 426A OATE: 10/14}94 PAGE: 2:
iL SToo'l' TYPe

.EfFECTS RHERENCE OOS£S DATA GAPS/COMMEIITS STATI,i$ IIIA11ln 28 day Study Oiarrhea, urgency of bow- AC1 UF -->100 No dota gaps. NED easphrte 03108}88 l #426.\ NOEL" 0.0000 IJIlJIkg el movements, urinary OPP R1O= 0.018000 EPA wrlfied 03/23}88 CAS Mo. 16672-87-0 0.00 ppII\ urgency. stlllllKh crl!llllpS; EPA RfD" 0.005000- WHO \

.. t 

### rtVfewed 1993 A.I. COOE: 099801 LEL'" 1.8000 III9Ikg ck!<:r or incr in appetite_ RtD/PR reviewed 02/10}94 CfR NO. 180.300 0.00 ppt No evfckmce of ClH'Clnog18'5.2700 DttCO: Tent E -(IID/N) enlclty In rab & Illlee. on IRIS. 

### TOlERANCE ANTICIPATEO It£S. VALUE USED 

### C') 

## CO 

# .--



# "''''

# - '000 FOOO FORM PET.tI (ppII) RESIDUE (ppm) AIt STATISTiC TYPE %CftOfI TREATE!) I II TAS RW (ppII)

03009AA o.r.OO1M 04001AA 0400IAA 04001M 04001DA 04001DA 04001,. 04001JA 04001JA 04001JA 04001JA 

### 05002,. OSOO2M 

# - .,00'" O'!102DA G5002JA 

# {

=:
06005,. 06005M 

# ....... 06<l06M 

# - 06013AA. 06013M 06013M 060130A 06013JA 06013JA 06013JA 06013JA**~07OO2AA** 

# _"'.

l0002AA 1000,.. l0002A11 P0010M 11001CAII

'. >**~LNUTS** 22 COOKED'FRESII-BAkED APPLES-FRESH 10 RAW-FRESH OR IfFS APPLES-FRESH 21 COOKED'lfFS APPLES·FRESK 31 COOKED-FRESH OR CANI!ED APPLES'FRESH 62 C{)(XEO'FRESII OR FTWZEN-IlAAEO APPLES-ruUED 10 AA\ol·fRfSK OR IiFS APPlE$-nRIED 22 C:OOK.E1)·F!t£SH-&AaO APPlES'DaIEO 62 coc«m'FRESIi 011 fROl£N'IIAK£O APPLES-JUICE 15 AAW-FRESH ()R CMHi£C APPLES'JUICE 15 RAW-fRESH OR CNfIfEO APPLES-JUICE 31 COOKUHRESH OR CAHUO AmES-JUICE 31 COOK£D-FRESH ()R CAttI/EtI CMERR1ES-FRESII 10 RAW-fRUH OR IfFS CtffAAIES-rRESIi 21 1XlOK£0-HFS CIlU1UES-FRESK 31 C{)(XED-FRES!I OR**CA~** CM£lUtlEs·nESH 62 cootJ:1)-FRESH OR fROZeM-8AKfD CHERRIES-DRIED 00 MOT SPt;CIFletl (NO CONSVlWTlOIt) CMEIUlIES-JUlce 15 !tAlHRfSH OR CM/NtD CI!£RRIES-JUICE 21 COOKED-IiFS FIGS 10 AAW-FRfSII CIt HI'S FIGS 21 COOKE'O-MfS F1GS 22 COOICEO-fRESH-8AKfD GOAVA 10 RAW-FItESM OR MfS GUAVA 21 COOK£l)-NFS GUAVA 62: COClkED-FRESH OR FlWZEIHMI(ED PINEAPPLE-PUlP 10 RAW-FRESK OR: HFS PIft'M"PlE·P.U1.P 21 COCllC£t)-NFS PINEAPPLE'PUlP 31 COO(ED-F!U:SK OR CANIiEtl**PI~E-ORIED** 10 RAW-fRESH OR'M'S**P1~LE~JUICE** 10 RAW-fRESH OR MFS PIIffI\PPLE-JOICE 15 RMl-FR£SM OR CAMMal**PIMEAPPLE~JUICE** 21 COOKED'lfFS**PINE~LE-JUICE** 31 COOKEO-FRESH OR: CANNED COfFEE 21 COOK£O-IfFS PAPR1KA 00 IIOT SPECifiED (NO COffSUWTiO'H CAMTALIXSPES-UtiSP 00 IklT SPECIFIED (NO CONSUHPTlOH) CANTALOIJPES-PUlP 10 ItMHItESH OR MFS CANTALOUPES-PUlP 21**~-NFS** Cl..IC\M8ERS 10 RA',.,.RESK CIt HFS C1..ICtJM8ERS 11 RA\I-FRESII-PICK1ED,CORHED,OR CURED 

# • HO PUt 3f1325 3f1325 3f1325 3F1325 3F1325 3F1325 3F1325 3F13-21 3f1325 3F1321 31'1325 3F1321 3F1321 3F1321 3f1321 3f1321 ·3F132:1 3fl321 4F1490 4"490 4f1490 NO PET# NO PETif \I/O PEl. m016 1f1016 1f1016 1f1016 1f1016 1F1016 1f1016 1F1016 4F1490 

# 9£_ 2F127'S 2f1275 2:F12:75 

### 9£2225 ""205 P 0.500000 P 5.000000 P 5.000000 P 5.000000 P 5.000000 P 5.000000 P 5.000000 P 5.000000 

### M5.000000 P 5.000000 It 5.000000 P 5.000000 P 10.00000 P 10.00000 p 10.00000 P 10.00000 po 10.00000 P 10.00000 P 10.00000 P 5_000000 p- 5.000000 P 5.000000 P 0.100000 P 0'.100000 P 0'.100000 

### P 2.000000 P 2.000000 

### P 

### 2.000000 P 2.000000 

### P 2.000000 P 2.000000 P 2.000000 P 2.000000 

### P 0.100000 p 30.00000 P 2.000000 P 2.000000 P 2.000000 P 0.100000 P 0.100000 0.030Cl00 1.710000 1.710000 1.710000 1.710000 1.710000 1.710000 1.710000 1.710000c 1.710000C 1.710000c 1.710000c 3.400000 3.400000 1.610000 3.400000 3.400000c 3.400000c 3.400000c 2.300000 

### '.300000 2.300000 0.100000 0.100000 0.1ClOOOO 0.200000 0.200000 

### 0.2(I0000 0.200000 0.100000c 0.100000c O.100000c 0.100000c 0.010000 1.070000 0.270000 0.270000 0.270000 0.005000 0.005000

# • 11.00 

# '.00 '.GO 

### '.00 '.00 

# '.00 '.00 

# '.00 '.00 

# '.00 '.00 9.00 

### ,.,00 30.00 

### 3<).00 

### "'.00 30.00 

# "'.00 30.00



# '.00 '.00 

### 5.00 100.00 

### 100.00 100.00 

### 23.00 23.00 23.00 23.00 

### 23.00 23.00 23.00 23.00 100.00

9.00 

### 2.00 '.00 2.GO 

### 3.00 3.00 0.003300 0.153900 0.153900 0.153900 0.153900 0.153900 0.153900 0.153900 0.153900 0.153900 0.15l9OO 0.153900 1.0z0000 1.020000 0.483000 1.020000 1.020000 

### 1.()2_ 1.020000 0.115000 0.115000 0.115000 0.100000 0.100000 0.100000 0.046000 .0.046000 0_046000 O.ll46OOO 0.023000 0.023000 0.0'23000 0.023000 0.010000 0.096300 0.005400 0.00S400 0.005400 0.000150 0.000150



# ,,---_._-------------ANTlC1PAlEO RtSIOOE 1NA:mMT1ON FOR CASWEll iruMSER 426A OATE: 10/14/94 

### PAG£: 3 

# "'" '''''''' NOEL- O.OOOO·mg/l':g 

### I-et**~ts~** 

### ut"1nary 

# I OPP RfO: O.Oleooo 

# I IEPA verified 03/23/88 

## CD CAS No. 166n·S7-0 O.M

# - ....-...... .. ...-d.

.........,...**~PA ~+n:** **n.~~** IoINO lut l"O!Vi-.t 19Q1 

# ..- A.I. CCOEt 099801 LElCFR No. 180.300 85.2700 OWCO: Ten E 

# • " enidt i" rats &. 

### aice. On IIUS.
TOLERANCE ANTIC1PATEO RES. VALlIE I,IS1;O FOOl> COOE FOOO FOOO ""'" flET •• 

# <"", ItESIOUE (pPa) AI STATISTIC 1YPE %CROP TREAlEO IN TAS RiItI (PPI\)**~** 1001QAA 

# CUCINE" 21 ctUm·NFS 

### 9£2225 P 0.100000 0.005000 

### 3.00 0.000150 ;\ l0011AA PVHl'KIM 2:1 COOI(EO·NF$ 3£2814 P 0.100000 0.02'5000 100.00 0.025000 \10011M PUMPklH 22 COCJ(EO- FRESH·ilIIk'ED 3£2814 P 0.100000 0.025000 100.00 0.025<100 ,10011AA PUMPkIN 62 COO(EtHRESH 

### ott FR02EtHIAt'fD 3£21114 P 0.100000 O.OZSooo 100.00 0."""'"

11".,..... PEPPERS,SWEET 10 R,w-FItESH OR NFS 

### 9£2262 P 30.00000 0.830000 

### 23.00 0.190900 11003M PEPPERS, MET 21 COOkEf)-NFS 9£2262 P 30.00000 0.830000 

### 23.00 0.190900 

# """" CHILI PeI'J'ERS 00 NOT SP£C1 FiEO (NO coeIS!.WlIOII) 9£'262 P 30.00000 1.070000 9.00 0.096300 11003A1> PEPP£RS'OYIlER 10 RA\HItESH OR NFS 

### 9£2262 P 30.00000 1.07OOO(J 

# '.00 0.096300 

# """" PEPPERS-OntER 21 COIXE1HtFS: 

### 9£2262 P 30.00000 1.07tlOOO 9.00 0.1I963IlO 1100lAO PEPPERS·OfI!eR 51 COOICEO·CANNEO 9£'262 P la.OOOOO 1.070000 9.00 0.096300 11004AA PHUEltlOS 10 'WHRESM Oft NFS 9£2262 P 30.00000**O.~OOOO** '.00 0.057600 11004M PIMIENTOS 21 COOKElHIFS 9£'262 P 30.00000 0.640000 9,00 0.057600 

# """'" P1MIENTOS 31 CCXJt::El)-FItESM OR CMlNED 9£2262 P 30.00000 0.640000 9.00 0.057600 11005AA TQoIATOES·WIiOlE 10 RAW·FRESH OIl NFS 3Fl321 P 2.000000 0.570000 22.00 0.125.1jOO 

# """'" TOMA.TOES ·wtiOt.E 21 COC*:Et·IIFS 3F1321 P 2.000000 0.570000 22.00 0.18400 11005M iCMA.TOES·\oIMOlE 31 cOOI:.m-FRESIf OR CANIfEl) 3F1321 P 2.000000 0.510000 22.00 0.125400 11005JA TOOTOES·JUICE 10 RAW·fRESIi**~** liFS 3F132:1 P 2.000000 0.120000c 22.00 0.026&00 11005JA rcmTO(5·JUltt 21 

### coot::En'ItF S 3Fl321 P 2.000000 0.12OOOOC: 22.00 0.026400 

# "_

T<:&TOES·M£E 10 RAW-fRESH OR NFS 3F1321 P 2.000000 0.01ClOO(lC 22.00 0.002200 

# "_

TQ!ATOES·PU1tEE 21 CtXlKEO-NF$ 3F1321 P 2.000000 0.010000c 

### 22.00 0.002200 

# "_

TOMATOES·POREE 31 COOKED-FRESH OR CANM£D 3F1321 P 2.000000 0.0100D0C 22.00 0,002200 

# "_

TCMA.10ES·POREE 32 CC!OKEO-FRfSM OR CAHlfEO-8AtEO 3F1321 P <:.000000 0.010000c 

### 22.00 0.002200 11005RA TIlI4ATOES·POIIEE 51 COOKED·CAMm 3F1321 P 2.000000 0.010000c 22,00 0.002200 11005TA TCWoTOEH)A$TE 21 ct:Xll;:ED-NFS 3F1321 P 2.000000 0.57OOOOc 22.00 0.125400 11005TA •TQltATOES'PASTE 22 coot::£l)·FRESIl-iIAK'EO 3F1321 P 2.000000 0.57OOOOc 22.00 0.125'00 11005TA Tot{ATOES-PASTE 31 et:)IXED·FRESIf 011: CAN\liED 3F1321 P 2.000000 0.57OOO(lC: 22.00 0.125liOO 

# "_

TOMATOES-CATSUP 21 CClOKa)'MFS 3F1321 P 2.000000 0.570000C 22,00 0.125400 24oo1M BAAlEY 21 COOKED-NFS 2F2711 P 2.000000 0.190000 

### 1.00 0.001900 24007M WM£AT·ROl.IGH 10 RAW·FRESII OR NFS 2F2711 P 2.000000 0.06800II 1,00 0._ 2.1j007AA WEAr·1tWGK 21 COOKElHIFS 2F2711 P 2.000000 0.""""" 1.00 0._ 24oo7AA WHEAT-RWGH 22 COOKED-FRESK·BAKED 2F2711 P 2.000000 0.060000 1,00 O. """'" 24007AA WKEAT-RO!.IGH Z3 COOICElI-FRESM'BOIlED 2F2711 P 2.000000 0,""""" 

### 1.00 O. """'" 24007GA WMEAT-Q£RH 10 IWl'FRESH OR HFS ZWS357 P 5.000000 0.136OOOC 1.00 0.001360 2400i'GA WilEAT·GfIlM 22 COOKEO·FRESII·8AkED 2115357 P 5.000000 0.1360001: 1,00 0.001360 2400"" wtlfAr·8RA11 10 RA\HRESM OR NFS 

### 21IS357 P 5.000000 0.23MOO1: , ,00 0.00Z380 24001HA WHEAT·BRAH 21 Ct)(XEfI·NFS ZM5357 P 5.000000 0,_ 1.00 0.0023S0 24007HA \!HEAT-BRAN 22 CO(J(£g-F/u:SII·tw:ED 2H5357 P 5.000000 0.23BOOOC 1.00 0.0023S0 

# ''''''''' \lllEAT·FlOOR 10 f!A\/-FRESH OR NFS 2F2711 P 2.000000 0.1I06SOO 1,00 0.00006Il 24007WA WMEAT·FLOJl 21 COOK'fl)-NFS 2F2711 P 2.000000 0.006S00 

### 1.00 0.00006II 2.1jOOiVA WHeAT-FlOJR 22 OOOKED·FRESH·BAXEO 2F2711 P 2.000000 0.006S00 

### 1.00 0.0<10068 

# • •

, 

# ,ANTICIPATED RESlotJ£ IIIFOO"tlATJOff FOIl: CASWEll M!R'!SER -4261. DATE: 10/14/94 PAGE: 10 'L STlOY TYPE EFFIICfil: lEFtREliCE OO$fS. OATA IITS STAtus**~** 28 d.y Study Olm-mea, unreney·of boW- ADI UF ·-:0100 Nt! data 98P$. Mal**coarptet~** 03/04188 Ceswl! #4261. MOeL.. 0.0000 lII9/kg**~I ~II.**  ur!,...ry 0Pf' RfO>< 0.018000 EPA verified OJ/23/88 CAS Mo. 166n-S1-0 • 0.00 pPf!I urgency, stOllltdl cremps; EPA RfO>oo 0.005000 WHO tut**rev!~** 1993 A.1.**COOE~** 099S01 LEL" 1.8000 II'GIl:g docr or incr in appetite. RfO/PI reviOW«f 02110/94 CFR No. 180.300 0.00 pp!II No evldenoe of carcfnogt100 OMoo: Ttnt E-(RfO/Pi'; tnleItyin rets & mice. On HUS.
TOLERANCE AHTlC1"PAIEO FOOO COOE FOCI) FO<X> """ PET.'**(~)** RESIDUE (pp!II) Nt STATISTIC IYPE % CROP TREATEO RES. 

### VAlUE 

### usa> IN TAS 1WN (pPII)

24007'WA wtIEAT

-FLCXJR lS COOKtO- FRESN' FRIEO lS003SA CANE SIJGAR 10 RAW'FRESII OR liFS 25OO3SA CANE '""'" 21 COOK£O-NFS 25OO3SA

# _ ...... 22 

### c()(x£o- FRES!HIAK£O 2500lSA CANE SOGAA 31 COOKEO- FRESII OR WIlEO 

# 25""sa SUWUHIOlASSES 10 RAW-FleSH OR WFS 

# """sa S:\.IGAA·MOlASseS 21 Cl)()(£.O-IfFS 2SOQ3SS SI../GAJI-HOlASS£S 22 cooall-**FRESH-BA~** 

# 25"''' SUGAA-ltC/lAsses 31 coot:;l:O'FItESM**~** CANIIEO 

### 2700"" COTTONSEED-OIL 18 PI«lCf:ssro OIL 

### 2100"" COTTOIIst:EO-QIL 18 PROCt::SstO OIL 

### ""0,"" COTTONSEED-MEAL 18 PROCESm:I OIL 271lO31/A COTTONS£eo'IEAL 18 PROCESSED OIL 

# "



# ..... UIME AIIO SKERlIY 10 jtW-FRESII Oft IIFS 4305aAA UIKE AIIO SHERRY 21 COOt:EO-IiFS 

# ,-, 1'ItLK-tK»('fAT SOl.. 10 RAW-fRESII OR NFS 

# '00000Il**MtLX~MQN-fAT** SOl 21 COOKED-HI'S 

### 5000<X>'**KIL,,~WON'fAT** SOt 51 COOKEl).CAHfm) 50000fA MiLK-fAT SOlIOS 10 RAW'fRESH OR NFS 50000fA MILK-FAT SOlIOS 21 COOKEO-NfS 50000FA MILK-FAT SOliDS 51 C()()I(lD-CAWEO 

## 'OOOOSA MILK SUG (lPtCT) 21 COOk'EtI-HfS 

# ,- "1LK SUG (tACT) 51 COOKEO·cAINED 53OO1BA BEEF-MEAT BYP 21 COOKEO·IIFS 53001BA BEEf-MfAT BYP 26**~O·FR£SN-PICKLEO,CORNEP.OR** CUREO 5300188 BEEF-DTM ORGAJI 21 COOKED-liFS 5300188 BEEf-DTH ORGAN 51 COOKEO·CAHttED 53oo10A BEEf-DRIED 21 COJKEO-lIfS 53001FA &t:Ef-fAT 10 RAW'fRUII OR WI'S 530011'A BEEf-fAT 21 COIXEO-IIFS 53001fA 8EEF'fAT 22 COOKEn-FRESII'8AAEO 530011'A BEEF'fAT 23 cooao·FRESII-BOILED 530011'A UEF'fAT 24 COOKED-fRESH-BROILED 5300lfA BEEf·fAT 25 coatEO·fRESH-fRIED 53001KA BEEF-KIMT 21 COOKEll-lifS 53001LA IlEU'LIVER 25 COOICED-fRESII-FRIEO 53001LA SfEf-LIVER 31**~'fRE$t(** OR CAHH£D 53001HA REf·LEAN 10 RMl- FRfSH OR IffS 53001HA SfEf-lEAN 21 CClOkED-MFS 53001'" UEF·LEAH 22 COOKED-FRESH'BAKEO 

# • 2F2711 P 2.000000 0._ IoF3142 P 0.100000 0.050000 4F3142 P 0.100000 0.050000 4F3142 P 0.100000 O.O'SOOOO 4F3142 II' 0.100000 O.O'SOOOO 4F3142 P 1.SOOOOO 0._ 4F3142 P 1.500000 0._ 4F3142 P 1.SOOOOO**O.~OOOOOC** 4F3142 P 1.SOOOOO 0._ RERfG iii 2.000000 0•....,. OF2312 P 2.000000 0.048000 REREG II 2.000000 

### 0.3"'" OF2112 P 2.000000 0.398000 9f217S P 8.000000 0.370000 9f2178 P 8.000000 0.370000 2F2T11 P 0.100000 0.100000 2F2711 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2f2711 P 0.100000 O.tOOOOO 2f2711 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2f2711 P 0_100000 0.100000 2f2'711 P 0.11'JOOOO 0.100000 2F2111 P 0.100000 0.100000 2f2T11 P 0.100000 0.11lOOOO 2f2711 P 0.100000 0.100000 Zf2711 P 0,100000 0.100000 2F2111 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2F2111 P 0.100000 0.100000 2f2711 P 0.100000 0_100000 2F2711 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2F2711 P 0.100000 0.100000 2F2711 P 0.100000 O.lOOOOO 2f2711 P 0.100000 0.100000 2f2711 P 0.100000 0.100000 2F2711 P 0_100000 0.100000

# • '.00 ,.00 1.00 1.00 1.00 1.00 1.00 1.00 ' 1.00 21.00 21.00 21.00 21.OQ



### 1.00 1.00 100.00 100,00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100,00 100.00 100.00 100,00 100_00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 

# 0._ 0._ 0._ 0._ D.OOO5oo 

## 0."""" 0.00400(1 0.004000 0.004000 0.010000: 0.0100s0 

### O.063SSO 

### 0.083580 1l.0259OO 0.025900 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0_100000 0.100000 0.100000 0.100000 0.100000 

### L() 

## CO 

# ..-

## • """\"



## • 

# . : '

i 

## ",m Ito. 16672-1:17-0

COOE.: O99$Ot 

### N<>.


# '000 ANTICIPATEO RESIOUE IMfOIItMATIOII FDA CAS1R;ll NlJMS£R 426A DATE: 10/14/94

NOEL_

lEl'"

Foe» FOflM



### 2:3**C()()!(fO~FR£SH~80IlEf)** 24**CXX»aaD~FR£SH~8ROll£O** 00 NOT SPEClFIEO (NO CONSUMPTION) 00 MOT SPECIFIED (110 COW$OItPT1OM) 23 COC«S:I-ftESH-80IlED 2S**ctlOKED~~-FIU£O** 00 MDT SPECIFIED (NO CON!\UIWTlOIO 00 MOT $f'EC1F1EO (NO CONStJ:IWtlON) 23**OOOKEO-fRESH~BOIlEf)** 

### 25**~·FR£StHRIEO** 00 NOT SPECfFIro (ItO CONSUMPTION) 21**COClM:EO~IffS** 21 COOKaI-MFS 21 COOKEO-NFS 21 Cl:lOK£O-MFS 00 NOT SPECIFIED (NO COWStlMPTlOIO 21 CQOKEt)-NFS 31 COOKED-FIfESH OR CAIiltEO 21 CClOKEO-NFS 21 CI'JOKEl)-MFS 26**COOKEO~fRESlI·PlCl(lEll,COI!.MEtI,OR** MEn 10 RAW-FRESH 01 NFS 21 coot:tll-MFS Z3**coot;ED~FItESM~801Lel)** 

### 2S COOICED-AtfStHltlEO Z6 COOKED-FJt£SII·Pla::leO,COfIMED,OR MEn 

### 21 et:lIXID-NFS 21 COOKED-MFS 

### 25**~~'ItESH-FR1ED** 

### 21 COOKED-IIFS 25**coot:ED-FRESK~FR1EI)** 26**COOKEO~'RESM-PICk1EO,~IIEO.OR** CUReo 21 COOICED-MFS 26 000kE0-FJt£SII-P1CKlED,CORMeD,0R 

### CUR£O 2:1 COClKEO-"FS 

### 25**~-FRES"-FRIEf)** 

### 21 et::tteD-MFS 31 COOKSHItfSM OR CAMIf£O 62 CXIOI(S)-FRfSM OR fROZEIHwceo 21 too;;:eo-MFS 

# • TOlERANCE AATlC1PATED PET.# (ppmI) RESIDUE (ppm) AR STATISTIC TTPE "**~** T!tEAT£t)

2f2711 2F2:711 2F271 I 2F2111 2f2711 

### 2F2711 2F2711 2F2711 2f271t 

### 2F2711 2f2711 2f2711 2F2Tl1 lF27t1

. 2F2711 2F27t1 2F2711 2F2711 2Fl711 2F2711 2f211t 

### 2f2711 2F211t 2F2711 2F271t 2F2Tt1 2F2711 2f2711 

### 2F2711 2F2711 2f2Tll 2f2711 NOTO!. NOTOI. 1IOT0l NOTOl NOTOi. NOTOi. NOTOi. IIOTIi. 

### P 0.100000 p**o~**100000 P**0~100000** P 0.100000 P 0.100000 P 0.100000 P 0.100000 p O.

## tooooo P 0.100000 P 0.100000 P 0.100000 p 0.100000 

### P 0.100000 P 0.100000 

### P O.tOOOOO P 0.100000 P O.

### tOOOOO P O.

### tOOOOO P 0.100000 P 0.100000 P**o~**100000 

### P**O~** 100000 P 0.100000 P 0.100000 

### P 0.100000 

### P 0.100000 P O.

### tOOOOO p 0.100000 

### P 0.100000 

### P 0.100000 p 

## o.tOOOOO P O.tOODOO A 0.008000 A 

### 0.008000 A 0.015000 

### AO.Ot5OOO A 

### O.OOtooo A 0.001000 A 0.001000 A 0.008000 0.100000 0.10000D 0.100000 0.100000 O. 1 (NJ(JC)O 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.11JOOOO 0.100000 0.100000 0.100000 01100000 O.

## tooooo O.

### tOOOOO 

# 0._ 0._
0.0t5000 0.015000 0.001000 0.001000 

### o.ootooo 0.008000 '''','



# •
• t,;>",

## ,~"4;{i,bful>

,,if.lf!!lf 

## too,oo tOO.OO 100,00 100,00 100.00 100.00 

### 100.00 100.00 100.00 100.00 

### 100.00 100.00 100.00 

### 100.00 100.00 

### 100.00 100.00 

### 100.00 100.00 100.00 

### 100.00 100.00 

### tOO,OO 

## too.oo too.oo 100.00 100.00 100.00 

### tOO.OO 100.00 

### 100.00 100.00 100.00 

## too.OO 100.00 

### too.OO 100.00 100.00 100.00 

### 100.00 PAGE: 5

RES. VAlUE US£t) 1M TAS RUN (ppm)

0.100000 0.100000 0_100000 0.100000**0~100000** 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000 0.100000**O~** 100000 0.100000 0.100000 0.100000 0.100000**O~** 100000 O.

### tOOOOO 0.100000 0.100000 0.100000 0.100000 O.

### tOOOOO 0.100000 

## o.tOOOOO 0.100000 0.100000 0.100000 D.

### tOOOOO 

# 0._ 

# 0."""'" 0.015000 0.015000 

### 0.001000 

### 0.001000 0.001000 

# 0._ <0 <0 

# ...-

## ---**~----~---** ..



### -.',' ••ii. >C.**~:~", "~,**  '



# •



# •

H 

# 88888gggg8888SS88SggggSggS8888 

# i 888888888888888888888888888888**~.** 

# 1-_-, 

# ii



# 167**~**..............**~~.~~~~~~~-** 

# --------

# 1f\t\U;**~** ':',"l,' I

TOlE1VJtCE ASS£SSfIIENT 

## nSTDf MVTIIfE CHltONIC ANAlTStS

## ~19N SU8§fWL!'
U.S>P6Puu.TlON • 42 STAns



### , 

## u.s: P'bPUt.AilOH • SPRlitG $EASON U.s" 'fOPUlATtOH

- SlJMMER $£ASCII U.S_' POPUU.TlOH

- fAll SfAStlM u.S,_tPOflUtATIOM

- WINTER SEASON 

# _!EAST HSIOH**~:A;aCTUL** REGION**~1tE:GION ~REGI,** *



# ......!..ts**~.J~IC** WHtTES**~MISPANIC** BLACKS JION-IiISPANtC OTHERS lEl=



### NURSJNG INFAMY$ 

### « t 

### YEAR Oll)} JDHMtS)WG INFAHTS 

## « 1 YEAR 0Ul) fEMt'ES (11+ TEAlS, PREGAAMT) 

### FEMia 13+ YEAAS, HURSlltG C1II,101WI (1-6 YEARS 01.0) CNIJ.D!tEN (7-12 YEARS 0Ul)**~** (t3-t9 TEARS OlD) FaW.!S (13-19 YEARS (JUl, HOT P1{EG. OR HORSING) KM,ES (20 YWS ANI) OI.OEIU fEMALES (20 TEARS AND OlDER, HOT PItEG. OR NORS)



# , ,j' TOTAL THII:C (HG/KG BOOT WEIGItT/OAY> 

### MRC* 

### !!i!!

-- 0.014716 0.015<883 

# ..."..,. 6.485667 0.0135T9 -0.014481 80.448394 5.340733 

### 0.014228 0.015238 

### 84.6>8033 5.6tt139 0.015262 O.Ot6493 9t.6303S6 

### 6.842589 

### 0.01'SO$O 0.016547**~.92nll** 8.152539 0.016574 0.018254 101.410311 9.331094 0.014273 0.014950 83.053583 

### 3;T60989 0.oH182 .0.Ot2737 70.7609'/'8 5.303267 O.Ot6872 0.018436 102.422283 

### 8.691117 0.015396 0_01668t 

### 92.669922 1.126239 0.015103 0.016309 ' 90.604100' 6.7013t1 0.010414 '0.011290 62.721150 4.865728 0.0140t7 0.Ot5066 

### 83.698683 5.826917 0.027759 0.040356 224.tge822 69.984128 0.04&403 0.06S7'57 365.314994 

### 96.409394 0.010654 0.011094 61.631050 

### 2:.44l422: 0.013584 0.Ot4373 79.851228 

# '.3823B9 0.035Q7 0.040S11 

### 225.060933 

### ZII.Z<2289 0.020924 0.021999 122.2t5672 5.96886t 0.012740 0.013261 73.6702t1 

### 2•• 522 0.010992 0.011562 64.233450 ,0 3.166561 0.Ot0542 O.ot09OS 

### 6O.S8S306 2.020918 0.010170 0.010619 58.993544 

### 2.4mp6



## , "'Current TMR't 

### does. J»t tnctude nw or pending tote1"ancec•

....New nmc inctudes nMf, piH'lding. end pubtlshed tolef'lltlC9$•


# • • DATE: 10/14/910 

# .....,

EFfECT OF ANTICIPATED RESIDUES

0.OOt624 0.001521 0.001654 0.001670 0.OOt6Sl)
O.oot766 0.00164t 0.001382 0.001826 O.OOt970 0.001639 0.001346 0.001'786 0.00l1'69 O.OO878t O.OO1t42 0.001483 

# 0."""" 0.002619 0.oot649 

### O.OOl3Z2 O.IlOCI903 0.00092' 9.02465 

### 8.45-096 9.188S0 9.27'9t1 9.16&94 9.81122 9.11759 7.67868 

### 10.144Z7
10.94525 9.

# urns 7.41951 9.91%6 t5.38102 

### 4S.7806;!

6.34570 

### 8.23956 24.49352 14.55129 9. """ 

### 7.3-\266 S

...... 5.t35a8 

# co (0 

# ...-

### ;

TOlERANCE ASSES_HT SUl!MAAY FOR**Eth~¢O** USING AHTTCIPATeO RESIDUES CASUElL tl426A DATE: 10/18/94

AHAlYSIS fOIl: POPUlATlOH**stJa~GJWlJP:** U.S. POPULATION**~** 48 STATES EXISTING ANTICIPATED IIESIPIJE$ (MLISKED ONLY) 

## -

RESULT IN AN ARC OF: 0.001572 Me/KG/DAY THE EXISTING ARC IS EOUIVALENT TO! 8.733 "Of TilE ADI.
PROI'O«O HEY ANTIC IPAlEO RESIOUES (CURRENT PET! TIOff OHly) RESULT IN AN ARC Of: 0.000034 MG/KG/DAY TIiESf NE\J ANTICIPATE!) RESIDUES Will OCCUPY: 0.191 X Of THE ADI. 

### If TilE HEY ANTICIPATEO RESIDUES (CURRENT PEtiTION ONLY) ARE APPROYfD TII£ RESUlTANT Me \llll BE: 0.001606 I«i/KG/DAY TKE NEY ARC Will OCC'Uf'Y 8.924 X OF THE ADI. 

### OTIIER PENDING ANTICIPATEO RESIOUES EXCLUDING TilE OJRREIfT NEil PETITIOH KAVE AN ARC OF: 0.000018 ltG/KG/DAY TillS ARC Will occupy 0.101 X Of TtlE AOI • 

# • IF ALL PEHOING ANTICIPATED RESIDUES (INCLUDING TilE 

### CURRENT NEW PETITION) ARE GRANTED



# • THE RESUlTAHT ARC Uill BE: 0.001624 MG/KG/DAY TItE**TOTAL,~RC** \I(ll occupy 9.D25 

### %Of TilE ADI.
AIlALYSIS fOR POPULATION sua-GlWUP: NON-ituRSING INFANTS 

### « 1 YEAl!: OlD)
EXISTING ANTICIPATEO RESIDUES (PUllISKED ONLY) RESUlT IW AN ARC Of: D.008227 HG/ICGJI)AY TKE EXISTING ARC IS EQUIVALENT TO: 45.704 

# "Of TilE ADT.
PROPOSEO NEW ANTICIPATED RESIDUES (CURRENT PETITION ONLY) RESULT IN AN ARC OF: 0.000533 HC/KG/DAY THESE NE\I AIUlCIPATED RESIOUES \llll occupy: 2.962 X Of TilE ADI.
IF TilE HE\I ANTIClPATED RESIDUES (CURRENT PETITION ONLY) ARE APPROVED THE RESUlTAMT ARC I./Ill BE: 0.008760 HG!KG/DAY TilE NE\I ARC \lILL ocCUPY 48.667 "Of TilE ADI.
OTIfER PENDING ANTICIPATED RESIDUES EXCLUDING TKE CURRENT NEW PETITIoN KAW All AlI.C DF:' 0.000021 MG/KG/OAY TillS ARC WilL occupy 0.114 "Of TKE ADI • If All PEnDING AHTICIPAlED RE$lOUES (INClUD1NG TKE CUIUIENl,itE\aETlTIOto AAE GRANTED TilE RESUlTANT ARC wIll liE: D.008781 MG/KG/DAY HIE TOYAl ARe lULt. occupy 48.781 X OF TRr ADI.
ANALYSIS fOR POPULATION sua-GROUP: C"llDREN**(1~6** YEARS OlD)
EXISTING ANTICIPATEO RESIDUES (PUBlISIiED OHlY) RESULT IN AN ARC Of: ' 0.004216 MG/KG/DAY TilE EXISTING ARC IS EtXJlVAlEWI TO: 23.420 X Of TilE AOI.
PROPOSEO HE\I ANTICIPATED RESIDUES (CURRENT PETITIOH OHlY) RESULT IN AN Al!:C OF: D ;000153 MGjKG/DAY TIiESf NEW ANT lelPATED RESIDUES \llll OCCUPY: 0.852" Of TilE ADI.
If TilE NE\I ANlIC}PATEO RESIDUES (CURRENT PETITION OtoiLY) ARE APPRQVEt) TNE RESUlTAItT ARC \llll BE: 0.004l69 MIl/KC/OAY IHE NEW ARC \JIll OCCUPY 

### 24.2n "Of THE ADI.
OTIIER PENDING ANTICIPATeD RESIDUES EXCLUOING TNE CURREIlT HE\I PETITIO# HAVE AN ARC OF: D.000040 MG/KG/DAY TillS ARC \lILL occupy D.221 ox Of TilE ADI.
IF ALL PENDING ANTlCIPATED RESID\J£S (lHClutJING TilE CURRENT N£\I PETITION) AR:/! GRANTED TilE RESULTANT ARC \lILL BE: D.DG4409 MG/KG/DAY THE TOTAL ARC \lILL OCCUflY 

### 24.'94 

### :t. Of TilE ADI. 

# 169

# ..~

# '. 'M)..f

# a..

TOlERAMcr ASSfSSMEMT 5tsJ'EM ROUTINE CtIltotHC ANALYSIS

-, '# 

### "> 0.00 PC* l£L_ 1.8000 

### -sit, 

### 0.00 :0; lll!l'll E UfO

,**,~** , lOTAl. TMRC (MG/J:Q BOOY WEIGHT/OAYl

# ~!l0!I """"'" CtJRItEMT TMRC'" 

### NEW TMRC**

### U:$~,:}IOfIOU.TlOH • 48 STATES 0.014253 0.015420

### U.$~**'~TlON** - SPltUfG S!A$ON 

### 0.013113 0.01401S U.S.' P!:IPULATfON

- SUHMER SEASON 0.013640 O.0146SO U.S. POPlUTIOM " FALl. SOSON 0.014$13' 0.016044 U.S.,POPIJt.ATlOlf

- WINTER stAso. 0.014670 0.016138**NOII:~Sl** REGIa. 0.015909 

### 0.017588 tIORtti taTRAl Rt:GION 0.013869 0.014546 SOlItIERW REGIOH 0.011476 0.012431 WESTaut REG10N 0.016323 

### 0.017881

## Hl~~'lics 0.015108 0.016390**NON~MrSPAM1C** 

### WHITES 0.0145&9 'O.0151'9ti ~K1spAlnC**  8lACKS 0.010178 0.0110$4**14OH~"t$YAN1C** OT}l£RS 0.013683 0.014731

# ~fB INFANTS 

## « 1 YEAR OlD) 

## O.02nn 0.039868 )Qt-MSUm UIFAIflS 

## « 1 lEAR OlD) 

### 0

....... 0.064043 

## feW.u (13i" YEMS. PREGlMHT) 0.010404 0.010!!4'**'~$** 13+ YEARS, fllJR'SJI4G 

### 0.013113 0.01391)2 ctlll.iJft£N <1-6 Y£ARS OlO) 

### 0.034559 O.1l39643 CMllbRfN (7-12 YEARS 01..0, 

# D."""'" 0.021500**~** (13-19 YEARS OUt' 0.012496 

### 0.013011 fEMALES (13-19 YEARS OlD, NOT nEG. OR NUIISIMG) 0.010647 0.011217 tW.ES' (2'0 'fURS AND OlDER) 0.010201 0.010565 fatAl.!:S (20 YEARS MIO OlDER, HOT Jt1i:EG. OR M\JRS) 

### 0.009703 0.010151 

# ....

# - AS PERtaiT Of

# 'FO
85.666406 

### 78.192489 81.38S'&94 89.13'5300 89.653528
97.111761 

### 80.812483

...0S97'J4 

### 99.371683
91.056944 81.753628 

### 61.40e950 81.841500 221.490161 355.1'94361 60.245367 

### 17.232t!03 220.137S83 119.444861 

### 72.315922 Q.3t8311 

### 58.69S0 56.396100 

# .. Dtff'a!SICE AS PIIK:£NY OflFO**6.~7** 1.:$40733 

### 5.611139


# ........ ••152539**9~331tw4** 

# 3.- 5.303267 8.691117 

### 7.1l6239 6.701311 4.865128 

### 5.826911 69,984128 

# 96._**2.~2** 

# 4._ .:.a.

......

5.968861 

### 2.894522**,~.** 3.U6S61 

### ',2.020978

2.492606

*ClJrrent llIItt 

### does Mt 

### ini:tude 

### new or pendfl19 

### toleranctil•

......M$t TMRC Inclu::1&5 MIl, pending, fit'Id pWlfflhed tolerance.•



### '": 

# • •

, ,

DATE: 10/14/9<0 

### PAGE:

EFFEct Of ANTICIPATED RESlDOES
ARC 

# "



# .. 0.001553 8.62621 0.001459 8.10745 0.001538 

### 8.54595 0.001610 8.94443 0.001601 

### 8.89502
0.001652 9.17681**O.OO1~** 8.79891 

### 0.001344 7.46932 0.001732 9.61963
0.001921 10.67066 D.001551 8.65128 0.001325 

### 7.36334 

## o.com:. 9.517Q2 O.00Z661 14.78433 

### 0.008427 46.81897 0.001092: ••061191 0.001389 1.71664 0.00W3**2:3.~1Z3** 0.002555 14.19619 

### 0.001620 9.00122 0.0012711 

### 1.05538 0.000936 5.20041 0.D00S46 4.69887 

# o I"- 

# ..-

# •

• I, Cynthia L. Giles-Parker, Product Manager, Fungicide-Herbicide Branch, Registration Division, Office of Prevention, Pesticides and 

## Toxic Substances, U.S. Environmental Protection Agency, do hereby certify that the pesticide product listed below is currently 

## registered with this Agency under the Federal Insecticide, Fungicide, and Rodenticide Act, as amended. that the label attached is a true, correct, and compared copy of the correspondence of 

## record, and that the product may be sold and marketed in the United States of America for the uses indicated on the label. The product registration listed below has been issued to:

Rhone-Poulenc Ag Company

. P.O. Box 12014, 2 T.W. Alexander Drive Research Triangle Park, North Carolina 27709 EPA Registration Name of Product 264-418 CERONE



## IN WITNESS WHEREOF I have hereunto set 

## my hand and affixed the seal of the U.S. ENVIRONMENTAL PROTECTION AGENCY this**~** 

## day of 

# £f'('1 A.D. 1994



## Cynthia L. Giles-Parker Product Manager #22 Fungicide-Herbicide Branch Registration Division (7505C)



# 171r

# ~ RHONE-POULENC_



# .. RHONE-POUlENCAG COMPANY



### Septermer7,1994

Ms. Cynthia Giles-Parker 

### OffiCe of Pesticide Programs (H7505C) Document Processing Desk (CERn 

## u.s. Envlronmenlal Protection 

## Agency Room 266A, Crystal Mall 2 1921 Jefferson Davis Highway Arlington, Virginia 22202



### Dear Ms. Giles-Parker:
Re: CERONE® 720, EPA Reg. No.: 264·418



### Please provide us with five (5) certificates 

### of registration for the product relerenced above. Please include Ihe following information on each certificate: (1). Registrant:

(2). Name 01 lhe Product: 

### Rhone-PoulencAg COmpany 

### P.O. Box 

### 12014. 2T. W. Alexander Drive Research Triangle Park, North Carolina 27709
CERONE® 720. EPA Reg. No. 264-418 

### (3). The phrase wUhjn the body ofthe paragraph:**~**

### ...that Ihe produc1 

### may be sold and marketed in the UnUed States forthe uses indicated on Ihe**fabel.~** 

# CIt Please conIact me 

### at (919)549·2122 

### should you have

### any questions**~garcnng** 

### th'ls request.**Sinc~Hely,**

# :~/-&&ft[o**(~ilHurSey ~egjstralion**  

### Documents Specialist 

## • 

## • • 

## • •

•••• 

## •

••

•

## • • •• • •

••••



# . '

# ..

..

# .. •••••• 

## • 

## • ••••••



## • •

•



# ... •



## • • •• ••



# ....

# . ' 

## • 

# •

•• •••• • 

## • • ••

YO BOX '2D!4 ]' i ',','**!'lV,A"'~;Lf1** DR--,-", "ESEAR;::), iR'_"'WiLt: i-'/II'!"- he ;!"!J:) :'JIJIS49-?W(l !N7El';},AliGN-",L 1f;H f>L:!IBrH**4'f'-'~.F"** -_,","',','1 "i."S,,-**A~(** ;;'r· 

### Excoifenco Hl Perlorm?flCe Pnde In 

### AchJCllcme-nr HleAt,AfIOh':'1 cLsrmfJl; 1'01-1 SfI'V,U:S 'c-**~Ll ~,,_I"(JLI"** **~,",)}jr{" ,\LSW~f-!,\!\:~r_**  Ai-';

__**C~** 

# 172**~-~~** 

### .. 

### - 

# ._------------------

## UNITED STATBS ENVIRONMENTAL PROTECTION AGENCY 

## Office of Pesticide Programs Registration Division

, _ ',("'?/J 

## iLl"'**~** 

## Warren A Davis RHONE-POULENC AG COMPANY BOX 12014 RESEARCH TRIANGLE PARK Ne 27709



## Subject: Label Amendment Submission of 06/28/93 

## to Comply with WPS Labeling Requirements EPA Reg Nr. 264-418 PREP PLANT REGULATOR FOR COTTON 

# e Dear Registrant:



# • The labeling cited above and submitted in connection with registration under the Federal Insecticide, Fungicide, 

## and Rodenticide Act, as amended, is accepted subject to the comments listed below. Based on your certification, the Agency has accepted only those changes to your labeling which are necessary to comply with PR Notices 93-7 and 93-11, which reflect the WPS 

## labeling requirements of 40 CFR part 156, subpart K. 

## Any other labeling changes submitted in connection with this amendment application and not directly related to compliance with PR Notice 93·7 or 93·11 have neither been reviewed nor accepted by the Agency. If you wish to make any such changes, you must submit a separate amendment application proposing them. If your product registration is currently suspended, acceptance of this labeling amendment does not affect the suspension in any way. A copy of your proposed labeling stamped, "Accepted with comments", is attached. Make any required changes described below and send three copies of final labeling as soon as it is available to: Document Processing Desk (FIN-LABEL) Office of Pesticide Programs (H-7504C) u.s. Environmental Protection Agency 401 M Street, SW Washington, DC 20460·0001



# 173

## RHONE-POULENC AG COMPANY EPA Reg. 

## Number. 264-418 PREP PLANT REGULATOR FOR COTTON 

## Application date. 06/28/93 Original Submission



# •

• Hand or courier deliveries of final labels may be made to: 

## Document processing Desk (FIN-LABEL) Room 266A, Crystal Mall 2 1921 Jefferson Davis Highway Arlington, VA 22202 

## You have not transcribed the first paragraph in the Agricultural Use Requirements section exactly as prescribed in the Main Labeling Guidance

. There is a typographical error(s) in the PPE statements that you added to the Precautionary Statements. There is a typographical error(s) in the Spanish language text. 

## Please correct the typographical errors circled on the draft before printing final labeling. 

## In your final labeling, the UAgricultural Use 

## Reguirements R 

## text must be contained in a clearly separate box. This box may be set apart by a line, by another graphical device, by a different color background, or in any other way that clearly distinguishes it from surrounding text

.



# \ incerely, 

# r:J**g~atii/support** Branch egistrat10n DivIsion



# 174

...................•.••......•.•.**~~~~~~~~~~-**

### Admin; 264 -418 

### Analyst comments: TypO in 

### F-2: replace the word "expectations" with the word "exceptions".

Add 

### to apron statement in PPE 

### "mixing, or loading"

.



# •

•

175

# ETHEPHON FOR COTTON AND TOBACCO

For Commercial Use Or Agricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: E1hephon (2-Chloroethyl) phosphonlc acid"



### ........................................55.4% 

## INERT INGREDIENTS:

......................................................... ,..................,......,......"

.....................44.6% "This product contains 6 pounds elhephon per gallon. 

### EPA Reg. No. 264·418 EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usled no entionde fa etiquotu. busque;a aiguion p'il:i'a quo so fa expliquo a usloo en dotaJlo. (Ifyou do not understand Iho 

### laboWindJ!Ofnoone 10 explain illo

### you in 

### detail) 

### For MEDICAL And TRANSPORTATION EmergencIes ONLY Call 24 Hours A Day 1 8

### 800-334-7577 For**~** 

### InformaUon Call 1-800-334-9745 Tho use of fhis producl or a varioly of planl growth regulation uses are proloctod by 

### United lales and foreign pafonls including

• U.S. Patents 38.791,188 and 4,240,B 19, No liconse Is granlod 10 use this product in counlries other Ihantho United Sialos or for any use not contemplaled by this label. Liability lor palent infringement may result from use or sale of this product outside Ihe United Siaies. 

# STATEMENT OF PRACTICAL TREATMENT IF IN 

### EYES: Hold oyolids open and lIush with a g6nllo stream 01 water lor at loast 

### 15 minuto$, Get medical allenlion. prolorably an ophthalmologist 

### IF ON 

### SKIN: Immedialely wash skin with plenty of soap and water. 

### IF SWALLOWED: Do not induce vomiting. Promptly drink 

### a targQ quantity 01 milk, 

### egg whitos. gelalin solution or il these are nol ayailable, drink large quantkies 01 wator. AYoid alcohol. Call a physician immediamly. 

### IF INHALED: Remove victim to frosh air. If nol brosthing. give arrilicial respiration. Adminisler oxygen if**necesalitV;:t'~)medical** attenlion. "fi!lJ C(IMMK:ffS rll 

## n','**t~lI**..r OMNl 

# PRECAUTIONARY STATEMENTS DANGER t;,

...1t:r II>"**~\·Jcr"t** t,.,,,wtldd,,. F'untlidd<:. m,,1 Ro<I,mtld.t" Act 

## HAZARDS TO HUMANS AND DOMESTIC ANIMALS " M,rndd. '"' 

## u,"

....."dM

• CORROSIVE. Causes eye and skin damage. May be fatal ifabsorbed through skin. Harmlul ifswalioweBS

__

lWI_'

## ~~.!..JdW'U.~%~;);.#ill1-L'''-'~_.\\,_ih'9~':..'· pray miSI. 00 not gol in eyos, on skin or on clothing. Keop away from domestic animals,

## ~-

## ~ NOTE TO PHYSICIAN Thero is no spocific anlidote. All trealment should be based 011 observed signs and symploms ofdistress in the patient. Overexposure 10 malerials olherthan this product may have occurred. Victims 01 seyere overexposure, by inhalation, shOUld bo kopt under modical observation lor up to 72 hours for dolayed onsal of pulmonary edema. In a victim 01 oyer·exposure by ingestion, carelul gastric lavago is required due to tho possibility 01 slomach or esophagoal porforation. This material is an acid, but use ofalkaline subslances to neutralize it is contraindicated. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Applicalors and other handlers musl wear coyeraUs ovor short-sleeYod shins and shon panlS, waterprool gloves, chemical-resy,lant foolwear plus socks, protective eyewear, chemical·resistant headgear lor overhead exposure and chemical-resislanl aprorywhe!)) cleaning euipmenl. 

### L/ Discard clOlhing and olhor absorbed malerials Ihal have been drenched or heaY·lly contaminatod with this producfs concenlrale. Do nol reuse Ihem. Follow manufacturer's instruclionslor cloaning/maintaining PPE. II no such instruclions lor washables, use detergent and hoi water. Keep and wash PPE separately lromothor laundry. When handlers use closed systems, enclosed cabs, or aircrah in a manner thai meets the requirements lisled In Ihe Worker PrOleclion Standard (WPS) for agricultural pesticides {40 CFR t70.240 (d) (4-6)J, the handler PPE requirements may be reduced or modified as specilied in the WPS, 

## User Safety Recommendations Users should wash hands beloH) eating, drinking, chewing gum. using tobacco or using Ihe loitel. Remoye clothina immedialely il pesticide aets inside. Then wash body thoroughly and out on clean dothing, 

# 176---**--~----- -----~-~--------** 



## ENVIRONMENTAL HAZARDS Forterrestrial uses, do not apply directly to water, or 10 areas WhtH9 surfaC(! water is present or to intertidal areas belowthe mean high water mark. Do not contaminate waterwhon disposing of equipment washwaters. 00 

### not contaminate water used for irrigation ordomestic purposes. 

## USE PRECAUTIONS Do not apply PREP'»' brand Ethephon through any

### type of irrigation system. Avoid spray drift to nearby crops as this product will cause modifications in plan! growth. Ptan! injury or reduced yields will result. 

### Do not plan! another crop within 30days aftertreatmen!. Mix only the amount of sprayyou expect 10 use Gach 

### day_ 

### Do not allow mixed solution to stand overnight. 

# DIRECTIONS FOR USE It 

### Is a VIolation of Federal Law to use thIs product In a manner Inconatstent wIth tts labeHng. Read entire label before usIng thIs product. Do not apply this product in a 

### way that will contact workers or other parsons, either directly or through drift. Only protOCled handlers milY be in the area during application. For any requiromenls specilic to your Stato or Tribo, consult the agoncy responsible lor posticide regulations.

this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 

### 170. ThIs slandard contains i for the prolection 01 agricultural workors on farms, forests, nurseries, and greenhousos, and handlers 

### of 

### tt contains requirements for training, doconlamination, notification, and emergency assistance. It also and expectations partaining to tho stalemonts on this label about personal protective equipment (PPE), and restricted·entry intervals. The roquiremonls in Ihis box only appfy 10 uses of this product that arc covered by the

Standard. 1Il0 001 enter or anow worker entry inlO treated areas during the restricted·entry inlerval (REI) of 48 hours. roquirod for early entry to trGatod arGas thnt is permitted under tho Worker Protection Standard and that involves conlact i that has beon traa1ed such as plants. sailor water is coveralls OVor short-sloeved shirt and short pants, waterproof ,"'"0-,1 footwear plus socks, protective eyowoar and chemical-rosistant headgear for overhead exposure. 

### II

not contaminate water, food. or food by storage or disposal. conlainer is broken or contents have spi!lod, follow all prqcaulions indicatod above and dean up immediately, Belore cleaning up, full longlh trousors, long Sloeved shirt, protective gloves, and goggles or face shield, Soak up spill with absorbent media such sand, earth or other suitabfe material and dispose of waste at an approvod wasle disposalfacility.

# l~:~,~~:~~"~;, DISPOSAL 

# I! wastes are ncutaly hazardous. Improper disposal 01 oxcess pesticide, spray mixture, or rinsate is a Violation 01 FedGral law. these wastes cannot 

### be disposed of 

### by use according to label Instructions, contact your State Pesllc/de or Environmental Control 

## I"'""cvorlh. Hazardous Waste representativo at the noarest EPA Rogional Office for guidance. NER DISPOSAL I I I the empty conlainers. ollorfor in a sanitary ill, i 

## GENERAL INFORMATION COTTON A fonar spray of PREpm brand Ethephon will accehm\le opening of maturo unop&ned cotton bolls and onhance defoliation whkh can result in earlier harvest wifh an increased recoverable yield.**PREP1~** brand Elhaphon treatment on cotton allows increased efficiency from a once-over harvost. TOBACCO (FLUE·CURED): A foliar spray 01 PREpr>.! brand Ethephon promotes early, uniform**flyollowin~f** of maturo tobacco. PREPTM roducss curing timo, allowing mom ellident use of curing barn spaco, and increased control over harvesl schedules, SPRA

### Y PREPARATION Add 

### 112 1031401 the required amount of water to the spray lank. Start agitation. Add tile required amount 

### of PREPI'M brand Ethephon, and the remaining amount of water. Prepare only as much spray solution as can 

### be used on the day of mixing, 

### Do not allow spray solulion to stand overnight. Do not spill the concenlratod produci on spray equipment, or any airplane parts.



# 177

# --------------_.- -----.- 

## - --- ..

ANY SPILLS SHOULD BE RINSED lMMEDJATElYWITH PlENlYOFWATER. Use of a nurse lank is highly recommendod lor avoiding possible spills of conconHaled lormulalion on spray equipment or any airplano 

### parts. TANK MIXTURES WITH DEFOlfANTS AND INSECTfCIDES PREpm brand Ethephon is compatible with OEFl, FOLEXS:, Drapp?, Harvade3

. Melhyl Paralhion, Guthion r
, and Malalhion4. PREprn 

### may bo appliod in sequence or as a lank mi:duro (00 NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use precautions and rate per acre rfXX)mmondalions 01'\ labels

### of products 

### applied as tank mixlur(lS or in sequence with PREP TIl brand Ethephon, In some cases sligh! reduction in boll oponing response has been observed when lank mixos 

### with defollanls wore ullod. 

### Good agitation 

### in 

### th& spray tank is essenllal and a tank mh:ture should not be allowod to stand wilhout agitation lor more than 5to to minutes. Read and ObsOrY(1 all appropriate label use directions and precautions for the dofollants and insoCliddes usod. 

### NOTE: UndGr certain conditions, tank mixturos of PREpnI brand Ethephon wilh desiccants containing sodium chlorate could result in the formation of hypochlorous acids which on heating will emit toxic chloride fumes. 

### EQUIPMENT CLEANING Because of the acidic naturo of this product, prolonged oxposuro to spray doposit will damage acrylic plaslics, certain paints, and metals, Rinse thoroughly with a detergent and water al! o:.:posoo acrylic plastic-type materials (o.g., aircraft windshields), and painted surfacos within an hour alter exposure to spray deposits, At the end of each day, rinse thoroughly With a detorgent and water all Ihc metal paris of tho aircral! and the assodated spray 

# tID equipment o:.:posod to the spray deposits

.



# •

178

## COTTON



## EXPECTED PREpTM ONE SPRAY 

### VOLUME 

### APPLICATION USE 

### CONDITIONS RATE GALLON (Gats/A) 

### TIMING PREpnt
DI 

# ,. LBS A,t. Acr•• "Ir" PREP'N 

### Hot and dry

### aO°F or 

### tt/3 1,0 

### 6 Apply whon the number 

### C?f Boll 

### Opener· highor 

### mafure unoponed bolls.is Dry 

### and 75 

### to 80c

### F 

### 2 1.5 

# , \5-50 

### 2,5 sufliciont to produce

### t~~ desired crop. See belOW,-for 

### Coo! but above 

### 65c

### F 

### 2213 2,0 3 tost of boll maturity. Treatment uniformly opens 

### or 

### bolls 710 14daysoarlior. 

## 1o, 

# "'" PAEPt\I + High soil moisture 113 

### 0.25 

### 24 15-SO 

### 5· 10 Apply 4 to 7 days**p~jor.** 

### to 

### FOLEX* 0' 

### PREP?!.! boll Defoliant Tank 

### High Il!rlilily levol 

### r 

### i Tobe j •.**~s** 

### Mix or 

# Ia**~** 

### I**treafmen::,,:lt~:** 

## 1o,**~ff,** 

### nol

### i~**pl~c**•. of PREP"

# "",i

- ..,.. Dropp2 High soil moisturo 

### 1/3 0.25 

### 24 

## to-So 3

- 

## to 

# IApply 4 to 7 days prior to Oefollant 

### Tank High IQrlility lavel 

### boll 

### oponing 

### Mix . To bo usod as Rank colton 

### i s'

## :_PI~~;_,froalmGnt**W~h,** i

### ~~t**i~** 01 PREpm bon 

# , Pre-CondItioner Hot, dry. 

### 2/3 0.5 12 Apply 4 to 7 days prior to 

### lor Defoliation Coot, above $5cF t ti3 

### 1.0 6 t5-50 

### 2-5 detoliant.**Enhances._~~~** 

### or crop defonation reducing deterioration of bollom crop Rank cotton 

### .od allows 

### lor earlier 

### ·pretreatment With 

### Defoliants Prior to PREP'fM Boll 

### Opening Treatment tt the cotton Is overly rank or taying down in tho mlddfes and good spray cowHage at tho bolts with PREPTl.4 is difficult, a pmtroatmont**w~h** defoliantswitt 

### be uselul to Improve 

## borr coverage with PREP''', Usedosage rates 01 PREpnl brand Ethephon recommended for 

### boH opening. Road and obsorve all appropriate tabal usadIrections and precaulions for tho dofotiant used. ·'fn California andArizona use a votume of no fess than 5 gallons per acre for aerial applications. 

# _011 Maturity A 

### boH is mature when it is too hard to be danta<:! when squeezoo between thumb and fingers, too hard to be sticod with a sharp knijo, and when the seed coat becomes tight brown in coior. 

### Use LImitations Do not excuod a maximum of2,0 Ib, altA torcomblnod uses at PREpni per acro peryear. Bolt Oponing: 00 not tank mix PREP'N brand Ethophon with a desiccant it the cotton is to be spindte harvosted. Pro-Condition for Defoliation: 00 not tank mix PREplM with desiccants untoss ptnnt desiccation is required. Do not use a dolotiant belore thero is sufticient mature unopened bolts to produce the dosired yiold (soe Generat tnformation s(!(;tion on howto test for bolt maturity. 

## WHEN TO HARVEST COTTON Do not harvost cotton sooner than 7days after a troatment with**PREp'~** bland Ethephon. Obsarva the treated crop and harvest whon optimum bolt opening has boen reached. 

### 100 earty harvest might reduco the full advantago 01 the treatment and tOO tate a harvest may result in reducod quality and toss of tint which wiUdrop tram the plant.



# 179PREpt'>I 

### .Spray Crop Pints/Acre 

### Ac<o Dir9Ctod Spray 

### 1 tl3 50 ·60 Application

OVot-Tha·Top 

### 1113-2213 40-60 Application

USE LIMITATfONS 

# TOBACCO (Flue-Cured Only)

SpecIfic Directions

Use drop nozztes. Choose TG or OC spray tips designed 10 apply 50 • 60 

### gpa at 35·40 psi 

## aod at tracfor speed 

### of 

### 2-3 mph. 

### Us. 2 nozzles per row; one on each side of fhe rowdropp4}d lowenough to direct the spray 10 IhD lDavos to bo riponod and harvested. Thorough spray is essential. Wilh a directod spray, 

### bfJ sure to harvest aU leavos 

# 'mo" I Treaf only when leavGS remaining on the sfalk are mafure, To ensura romafnlng leaves are mature. test spray several lobacco plants as described under the soetion ·Proper Time of Treatment" Use tho lower rate in 

### a normally malure crop when experience indicatos that minimum riponing inducoment 

### is roquired. Usethe higher rale whon fhe crop is heavy and has 

### a londency 10 be more rank or when lemperaWres are lower than normal. Always tgst spray to determine if Ihe lobacco 

### Is malulo enough to respond 10 treatment with PREP'" brand Elhgphon. Apply ovor·lho-IOp PREp1M brand Ethephon spray 

### as a fine misl using**t~ree** nozzles (one nozzlo lips over Iho conter of the pial'll, and one

## o~**~~~~e~~~1** so aU loavos aro coverod similar to Ihe



### . I.aento. UM a 'm'v , of40

### to 60 os!

Do nol apply PREPn.o brand Ethephon 10 immalure le<l;ves as this can resull in unsalisfactory coloring, welghlloss and reduc:od loaf quality. 

### Do nol 

### allow the crop to over ripen in Iho fiold aftar using PREpru brand Elhephon. since this may cause some reduction in yieki and quality, 

### Do net treat belore anfidpatod major slorm which could pre.ven! harvest and resul! in ClOp loss. 

### Do nof apply PREPN brand Ethephon if rain is expaclod**w~hin** 

### 4 hours. APPLICATION TIMING Successful resulls with PREpnI 

### caJi for Ircalmonl when leaves aro malure, nor overly rank green when sprayed. To oasily detormine Ihe proper Iraalmonl timing and Iho number otleaves per stalk ready for harvest, lesl spray several plants in more than 01'10 location in each field and obsorve the response. MaW"" loavos

### will begin to yellow In 2410 

### 72 hours, Toslleavesthat fail 10 yollow in 

### 72 hours are not mature and are nol roady for PREP'" brand Elhophon Iroalmonl.**Wa~** a tew days 10 permil furthor natural maturing, fhen make anothertosl spray or -malurily" check, .-wOOn you have contirmed Ihe number of leaves per plan! Ihal will color, you can dolermmo Ihe number of acres to Ire.al in order 10 

### fill**~ebam.** . Prepare your lesl spray by mixing one loaspoon 01 PREP'l>< in t quart 01 WaltH. Spray each test planl wilh about 

### 1

## oz. of this mixlure, covering 

### aU leaves with a fine mist. PREp1M brand Ethephon will not color immature sprayed leaves. WHEN TO HARVEST All maturo, sprayed !eaves**w~1** bogin to color**w~hin** 2410 72 hours arler PAEp1l>< brand Elhophon applicalkm, The yeUowing process IS woathor dopondont; cool wealher will delay, while hoI, sunny wealher can speed up Ihe process. Harvest Irealed Ichaceo whon loaves havo reached Ihe d&sired color inlensily. Do nol allow lobacoo to become over ripa berore slafting harvest loal drop can occur when lobacco is ovor ripe and leI! on Ihe slalk. " a number oftho bottom loavos have yellowed allhe time. otlrealmonl. thoy should be harvestod prior to spraying with PREPThl brand Ethophon. With an over-lho-top applicalion, harvosling can commence 24 hours aHar PREpl" brand Elhaphon applical/on depending on wealhor conditions or 10 avoid over dpa tobacco. TobaCCQ harvested 24 hours aller Iwalmonl win require more lime in Iho coloring phase 01 Iho curing process. CURING PREpnI TREATED TOBACCO Curing proceduros are as much an act as a science and oach cure musl bejudged on the basis ollobaccocondition, inferval between treatment and harvest. weafher and type of curing facility berore pro5criplion temperaluro and vonlilalion schedules can be established. To oblaln maximum qualilY, cam musl be laken 10 obsolve and control tho curing process closely, especially during Ihe late**"coloring~** and oarly**~drying~** slago$ of Ihe leal. PREpN brand Ethephon treated fobacco will have started the coloring process when halYosled, rGducing the lime roquirod in the coloring phasa of curing. Treatod lobacco should bedried fasler. II tobacco leaves aro groen or contain somo greenwhen harveSled, it may bo necessary to color Ihom for a few hours. 

### If Ihe 11J3ves are complnlely yellow, temperature and venlilalion musf

### beadjuslod in a manner to dry the tobacco as fasl as possible wilham scalding. Once tho leaf Is dried (3/4 dty), you should follow norma! procodures ror curing, Since PREpr>.< brand Elhophon !realed leaves cure laster, treated and untreated loaves should nol be cured logQther in Ihe same barn. 

# 180

# LIMITED WARRANTY AND DISCLAIMER The manufacturer warranlS (a) Ihallhis product conforms to tho chemical descriptfon on the label; (b) thallhis product [s roasonabfy lit tor the purposes sot forth in the direclions lor use whon**~** Is used in accordance with such directions; and (e) that the directions, warning and other sta10ments on this laOOI are based upon responsible exports' ovaluatlon of reasonablo tests of elfeclivoness, of 

### toxicity to laboratory animals am:! to plants, and of residues on 

### food crops and upon reports of Hold experience. Tests have not boen made on all \lariotios Of 

### in all stales or underall conditions. THE MANUFACTURER NEITHER MAKES NOR INTENDS, NOR DOES IT AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE, ANY OTHER WARRANTIES, EXPRESS OR IMPLIED, AND IT 

### EXPRESSLY EXClUDES AND DISCLAIMS All IMPLIED WARRANTIES OF MERCHANT-ABILITYOR FITNESS FOR A PARTICUlAR PURPOSE THIS WARRANTY DOES NOT EXTEND TO, AND THE BUYER SHALL BE SOLElY RESPONSIBLE FOR, ANY AND ALL LOSS OR DAMAGE WHICH RESULTS FROM THE USE OF THIS PRODUCT IN ANY MANNER WHICH IS INCONSISTENT WITH THE LABEL DIRECTIONS, WARNINGS OR CAUTIONS. BUYER'S EXCLUSIVE REMEDY AND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY FOR ANY AND ALL CLAIMS, LOSSES, DAMAGES, OR INJURIES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER OR NOT BASED IN CONTRACT, NEGLIGENCE. STRICT lIABILITYIN TORTOR OnlERWISE SHALL BE LIMITED. ATTHE MANUFACTURER'S OPTION, TO REPLACEMENTOF, OR THE REPAYMENTOF THE PURCHASE PRICE FOR, THE QUANTITY OF PRQDUCTWITH RESPECTTO WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHAll MANUFACTURER OR SELLER BE LIABLE FOR SPECIAL, INDIRECT OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLINGOF THIS PRODUCT. NOTICE TO 

### BUYER Purchase 

### 01 this product does not conler any rights under palients governing this product or tho use thereot in countries outsido 

### 01 the 

# e Unitod States.

lDEFand Guthion are registered Iradomarks ot Bayor AG, Germany. 2Dropp Is aregisterod trademark 01 NOR-AM Chemical Company. 3Harvade is a rogistered trademark of Uniroyal Company.**~Malalhion** 

### is atradomark 

### of Amorican Cyanamid Company

.



# •

Rhbne-Poulenc Ag Company P.O. Box 

### 12014, 2 T.W. Aloxander Drive Research Triangle Park. North Carolina 

### 27709 PREP is lhe trademark 01 RhOne-PoullH1C. FOLEX is a registered trademark 

### 01 Rh6no-Poulgnc. PREP111 brand Ethophon for Cotton and Tobacco (PENDING) Submitted

# _'_'93. 181PINHIWJd

### Jnstrvctlon. on 10m>. 

# "" OM",**".~."** 

## (A)

# &EPA Unltotl ,StaID& EnvlmM!lfrll.Gl PmlGdion Agoocy 

## Registration 

# IOPP IOOntificrNumbor 

### Offioo ofPestlcioo Prograrm.; (H7505C)

# ~ Wnshlng1af1, DC 20460 

## Amendment Applicationfor Pesticide: Other 

# 197005

t. 

### ComfWl'lfProducfNumber 

# I', 

# I" 264-418 

# C. G.
4,**Com~JProduet** (Name) 

### PM. 

# o Nonl} 

# o RostnclOO'



# PRE rand Ethephon for cotton and 22 5, NarnoandAddress ofApplicant (Include ZIP C<xfe) 

### I

# ~~uct ;,

# s;(,,;;:, 0'

# ~.ot~a:**:~~mpo'Won**and

# "b~';ng Rhone-Poulenc Ag Company 10: 

# 2 T. W. Alexander Drive RTP, NC 27709 EPA Reg. No. 

# D ChecXII thisis II

### rww ar:ldrcu 

### Product Name 

### III 

# rx
. Expfa!tl below FiMIprinted labels in response 

### to

# ~ ReMlbmitsicn in response to Agency roller datod AgOi'l¢)' kntordatod 

## r-
!-- Noll/icaoon· Explain below, 

# - "Me Too" ApphcalWrl_**~** Other"e:.plain 

### below, 

### I Ute addfunalpage{&) II nec&stlary (Fer saction Iand SQcoon IL) 

## Amendment to meet Worker Pl'otection Standard 

# requirements.



# !.!!I..


# ,. I 

# I'

# '~Mm. ElY'" Yo, rYes



# - I- Plastic



### . No No No

# j~~a;r**~;;:"!:** No:.

### P'" lI'Ytn,' N0P?' ; 

# I* Certificationmustbo C¢(Ittiloof Package 

### wgt, OOI'IflUfiOf 

### I 

# 13, Nat ConWllt!) lru0fm3ticn 

# I' 51"",) 01 i 

### , I i



### Dlabal 

# E3:S::t,;"",

..., ,P""''''' ,6. ""00"," ; 

# = o Other

### L--- I

# ~ N_ 

# In". Warren A. Davis 

## Senior 

# Registration Manager 919-549-2379 I 

# • Ioortily 

### that tho statemenls I havo fl'Iado on this 

### torm and all allacnmM1!5 thereto am

### true, 3CC\J/alQ and complete, I**~** thaIMY knowingly lebo Qrmit;:lnttding**~1tl1mnQflt** may be punishable

### by fino orimprisonment or 

## • :::

### ISII~Mr• 

## • • 

## • both lJI'loorappfitable law, 

## • 

## • 

# •• •

## •• • 

## • •• • 

## • • • • • 

# :. ,. 

# Ij

# .iJ ctY-"",-• 3 Hlo 

# . .. • 

# • •••

# 1tJtf)~ Senior Registration Manager 

# • • 

# •

# ... • • • 

## • 

# I' T, 5. On" 

# ... •• • • • 

## • • 

# .. Warren A. 

# June**2~** 

# 1993 • • 

## • • • 

## Davis 

## • •• 

## ••• 

# l**,a_~?** 

# """" ,"".12""', "m, wp,,·
... ,,. copy 

# '4**-,-~---**

## • 

## •••



## • 

# PAPERWORK REDUCTION ACT NOTICE and INSTRUCTIONS 

# "

# ~~~r~§~~~~i~~~~~~~~~~'~"~~thf:'~'~'!;'~tl.ectloo of infoNfllltlcn Is Htl'lMt«f 

### '-£earthing ¢xistlng dottD 

### sourees, gathedno and 

### Send COImI«It$ r*9*rding the 

### I::!urden 

### redUcing thl$ 

### burden, 

### to Chief, ";;;;.;..,.;,. street, • \lllthIngton. DC**2~6();** and to the ,t Uuhfngtoo, DC 20503. 

## INSTRUCTIONS: This form 1z 

### to I.:c UG:ed 

### tor' litt 

### afJPticlItlene for 

### row**r~istratlon.** end 

### use rflregistratlon,

### ~tJ resui:rl!issfon, to tlpplicltiOM 1Qr Mtfflc:lttiOM, HNit 'printed l!lbeting. reregtlltratioo, (lte. 1n order to prOCHS an epp{icctlon for fI ra\f registration subMitted on this tONI!, the tct{'OWing Nted.' l!USt iK:CQI!!PMiY tbe appl1catlom 1. CertifIcation with R«piMt to Cit.tioo ofOll:ta (EPA fQf'l!l 3$70-29). tIf not IIXetllpttd by «I eFR 152.81 (b) (4)1; 

### 2. Confidantlal Statement of fonmula (EPA form 8570'4); 3. fW"lIUlator'$**Ex~ion** St.1tOO'Mlt (I:PA (ONil 8510-27)( 4. five cup!u of dl"Oft tnhl'!t log; 5. Thr" cop;esc of illYf data s\..tmi tted; 6. Authoritatlon letter Wh,re appticabte; 7. H!ttriCH wft"re appl icable-. Sul::rnission of l4b@till9**~** Labeling M:QUld firtH be su!.mltt«i in the form of draft labets >lith all appticatiooa for

### pew re-gistrAtion. Soth draJt lAbels**~y** be in**t~** form of t';'p«f tllhd te",t on 8.5 x H ioch p<lper or II: Irt;Iektip of th.'proposM tabel. If**pr~ted** lUi II mockup, it shoold be cOf1SthlCtl!d ftl MICh II: W3'f at to foci Iittlte HOI·. fn nn &.5 x 11 ineh 11 til'. IW:bJp tabels significantly Ulat!er thllri 8.5 l( 11 illiChli111 Would be**~ted** OI'"! 8.5 x 11 fl"l(;h paper 10; 5.1";$100. Stba:iooion 01 tMtD**~** DAtil' SubmItted In rHlp(>rwt of this**~tlciltiQO** IiJJ$t I» !Hb:IIltted in lKtOnw!C1I' with Nt 

### notice**86~5.** 

## SPECIfIC lNSIRUCnONS: PtclIs.e read the imtructicro nated below befofd cOOlptf'ting this awtfClltlOO. rlrst 

# tit
dttermlM the t'fi,W of r&gi!ltr!!tim Ktten, Ihioo In !Hod; A, for lA1ich you l.Irf! stbnittfng thh-**~pplic.tloo.** fot applications !ltA::ffiltted tn CCN',cCtlOl1 ;.-ith Nm< Registration M;tl&Ul, Sect1Gf"'':: 

### t, HI, tind IV !lUSt be cC&pt¢ted 

### by the IIWHcent. For**~ticlitjmm** iltt.w1itttd 1(1**e~tiOf!** whh**~** rwghtration ectiOl'\$, f%l.ib'!!l:;ulornl. mtiHe.atiom:, reregi5tratlons. etc., Scctimm I, fi, 

### and IV must be**~Gmplet$d** by the applicant. !tock A**~** Chw.J: till! &f'P!'opflllte**~Ct10f!** for \<tilth you**l\r~** lIu1.:e!!ltdm this ferm. 

## SECTION I**~** This 'action !lUSt be uq>i0tod, sf. IIf?tic4ble, ftft all (69)sti"J>ti«"t utiont. 1. to=pQnyjPn:c.,Ic1: lk.Iaber**~** lrmert ytNI"**~** UWber, If (l()t 

### las i:»tm**3$$1~** by EM. ,hh;**~r** may have 

### ban usi{llWd to' 

### yw as l!I bMik reglMr$l"lt, a dl&tdbwtOf, or n 1m**estftbti~t.** If '11:J'Jr 

### p-tl4Jc:t i% r;tgigter£'d, jfiM:rt the PrOWet 

# -. 2. EPA proc:k.let**~r** - tf**~,** flit in til'"**~** and FH**~r** of the EPA PHXioct**H~.r,** 3.**p~** C\.-stfiC4tien**~ $~c!fy**  the pr"i'A>lI00 ehlssifieatlon of this**p!"~t.** 4. ProdJet I4lIIIile

- Enter the ewpt&tt! priXklct n.Ii!IW! of thb putlthk M, it witl**~r** co the label. 1M

_ JI'UIlt, 00 ilpedfic to this pr<'JdK:t ooly. DllpticutlOf! of**~;s** not pe-rn;ittMi 

## :w.cns prtXluca of tile ilMie cMpMl'f. DQ 

### nOt indudtt IM'f{ brand NIIM or**c~** lim desisnetiom:. 5.**~** 

### and**~** 01 

### AppliC$lt

- The I'W\W of the firm,zr peNon 

### /ltd ilddreit -sh«m lh yO!.lf' applicat!on 

### i$ tbl!: pUS«'! or fi/"n to 

### J4wm the**t~1stfntiCf1lfi!t** 

### be islloro. 

### If YlXl are acting \1'1 WI1alf of G!)Oth;rr ptlrty. yoo 

### mJ$t $\b;Iit autl\ori%!ltlanfrOO! tllat party to lIet for lhe'll Iii rt>gi&trlltioo NttcrC. An applicl¥1t \¥It rcsidl/'lg in the United Statim II'ltSt hnve 00 authorbed agu"lt residing In the untted Statoo to act for tl\(tM ill att reghtrnion utters. ,Mil r'\lIiIOO and IXlQPtetemiling addNn (If $\lCh an lIgt'nt Pl-Itt**atC~** thts appllcatton. 6. bpedittdl'{evielll**~** ftfAA $!teflon 3 (e) 3 

# on providac fOf"**e~ited** rtwlom of II!jlPlicatfOO3 f{;r**f~istratiOfi,** or**~ts.** to existing regfstruiom. fhit !Ire simil;!lr or fdentlul to other fJ"ticlde produt-ts that are (:Uf'rently**regh.u~red** with the EPA. ro order fer yoor IIWlk4tliXl to' be eltgible for**e~ited** reviw, yoo N4St provide tm: with the EPA ReSlsttBtiOfl Utsrber end prcd.let I'llI/l1e of thll! pr«loi::t yoo bel1lWe III**~irilHar** to or identical to your predJet. ,he prodoet 

### JlLl$t be simlt&r 

### or ldeotiul tn both fornottitiM MId In\wt&d WIll'S. 

## SECTION II**~** ,his section II'I.St I» (o:rpfeted for all**IIWlt¢atl~** subJlltted to t>IIm1d tllf!- rcghu&tton ooly 'Of l!I**cu.-r~tly** regisured prtduct (Alaanr.nenU, for b ruubmhsiM 11'1**r~e** tQ Ul "OUlCY tetter, for I'lOtif1(lItiornl to the**Agem:y~** fer'tlle**~{ssion** of (Ihal printed tabeling. for rereg!strction and for any other**~~len** that pertftin$ to 11 §p?£ifly**tea~rSaj$t*red****~.** 

### 1hi!" ll«tlon h.!:12! 12 

### J2! t)&ed for 1'1 lWW appt.i(l'Itton fer registrl'lthm. 1. su,jeet of t>tb!IriNiOl'"l

- Chock thO'! "Wiiel'lble bt;')C1; M1d previdw tlw**~** 11'ltt1li" date If**1JPPf~·d&te. Provi~**  II brief explanation of the purpote{s) for the submission, $Uth**~s** atht $ddition of Usite, P*5t or crop**{$pcclfY)~; ~&mend**  the confidEntIal natlffllUlt of for:rula by

.....; "rerC9istreticn slbha;h::o"; smwf'lIl**f~l** fev!,;i¢/'! of \)$***dtfeetl~."** AUath a ilGplIrate page 

### It IIddltlcml**g~e** is Mooed_ 

## SECTION HI (pacKaging: and**CQnUin~i!J.1.Q.t'1'f!itioI1)** 

## . 1'h12 $%ction wtt IX"**c~l{'tctl** fot" oil &F¥>I ieHioot Mbnltted in**e~.;;tim** with 

### new rcgl:l-tratloo Dr**#Wtittht~ ~tt.**  1. Type (if**fI~it\&** - Chwk tb:**~ovdBt€l** tAxk if y;xr p.rndv;;t ltiE b0 pM;b1ifrd In ">,;, mdirat(-J rw;<-31li-r>i! t)-"fW:$. Indicau til*" 

### sin of d\¢ indhddl.mi fCd¢l¢t$ v-d N;;Woor jX'f tet-lli\ c«>{aif)t!f". Z. lype of'Jltf!till!H CMt1l10&l"

- lr,jitllte hpe of**tlYlt~IMr ~n**  :#lkh ;;itt'w!Hphtcd, 3. L(lI(;iItitllh of U¢t fAmt'ltrtt&

-**~dfy** ,hI' mt £;y;tN1H !:If kit c;;flU1Mr& for '(OOf Ffodoct. 4. Sinta},4'i**ltataH·~¥ ~**  Gpedfy rfA rwt su>t&n" of 4lt retll\[ VmnliIYF5 ifF? )X@fl:t 

## !. LQt'o.: 

## cl 

## CM U-i_ti'ooo w Irxlitllt& Ifw to\:4t1Oh 0f th& 4$01' ulr&ctif-r-:-1< f¢f "fO'H**6.·~·tn** 

## Jiltdf 1M- U jlffh:w to F;yfrxt**~** 1r41utJ; I!w htnod 

### pnmu(t l.toot ;;; at1;tdlW: to hteH o:mtllirll1r• 

## ••• •••• 

## • •

## •• 

## SECTION 

# IY.**!tkmti~t** 

# point}

. Hde !«tfO!l 0.ln be**<:~!ijti¥J** ffir !lit eppticsti&w**f(j~ !l:~S'~tratk1'i**  w;tiOOk, l.e., new pn:ducts**r~lsTI"ntion,** rcsutnissioo, "m&"t()(l," reregl$trlltiOfl, etc. 

### 1-5. !lM'-«;pta41t:1>ry.

6.**~~~~~:** 

## • • 

## ••• ••••• • 

# 183**~~~«~** 

# <----------------------

# •



# •



# • WORKERPROTECTIONSTANDARD CERTIFICATIONSTATEMENT
Icertify that therevised labelingbeingsubmittedfor:



# PREP Plant Regulator
EPA RnGNQ. 254-418 P. ,



## is in completeaccordance with the labelingrequirements

## 01 PRNotice 93-7, whichreflects the reqUirements 

## 01EPA's labelingregulationslorworkerprotectionslatements(40 CFR part 156, subpart

## KJ. Where exact languageIs specified in thePRNotice, Ihaveused that languageexactly,in thelocation specified. 

# Jfurther certilythatnorevisions arebeing submittedotherthan those directedby PRNotice93-7. Iunderstand that itwouldbea violation

## 01 FlFRA if

## Jormysupplemental registrants weretosell ordistribute thisproduct afterApril 21, 1994, withoutamended labelingcomplyingwith the requirementsof40 CFR part 156, SubpartK.

.



## 8120/93 Warren A. Davis SeniorRegistration Manager

Theacutetoxicity categories (I, 

## II,

# nr, IV) for this product as entered in blocks 3-7on PartI oftheProductWorksheet are:

3 Acute oral toxicity


## 2 

## Acute dermal toxicity 2 

## Skin irritation potential I 

## Eye irritation potential
3 

## Acute inhalation tOXicity • " 

## • • 

## • • ••



## • 

## • • • • • 

# ·" 

## • • " 

# . • • • • • • • • • 

## • • • •

• •



# .. " 

# ,. •• 

## • 

## • 

# ... " 

# . 

# . . " 

# .. . . " 

# .

. " 

# ... • • • • • • " 

# .

• • • •

•



# 184

..**-.~**...

# --------------'**,-----------------~-~~~-~~-~-~-~-------** 

## •



# • ETHEPHON FOR COTTON AND TOBACCO

For Commercial Use Or Agricultural Use Only. Not For Residential Use ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid·

.._ ........._ ......."

..._ ........................_ ....55.4% 

### INERT INGREDIENTS: ...•.....••••.•••••....••.••.••.•••••..•.•••••••.••••....•..•••.•••.••..44.6% 'This product contains 6 pounds elhephon per gallon. 

### EPA Reg. No. 264-418 EPA Est. No. 264-PA-01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO
PRECAUCION**AI..--USU.AA~t>~ffiq~&1~UGto-.n~~** 

### ampliamonto. 

### For MEDICAL And TRANSPORTATION EmergenCies ONLY Call 24 Hours A Day 1-800-334-7577 

### For PRODUCT!J..S.E. Information Call 1-800-334-9745 Tho use 01 this product for a variety of plant growth (ogulation USGS aro protGcted by United States and foreign patents including U.S. Patonts 38,791.189 and 4,240,819. No license is granted 10 

### use this product in collnlries other than tho United States or lor any use not confompfat&d by this label. Liability lor patont infringement may result Irom use or sale of this prodUct outSide tho United States. 

# STATEMENT OF PRACTICAL TREATMENT
IF IN EYES: Hold oyelids opon and !lush with a gontle stream 01 waler for at loastt5 minutes. Get medical attention. preferably an ophthalmologist IF ON SKIN: Immodiataly wash skin with plenty of soap and water. Remove contaminated clothing and shoes. Wash Clothing soparately beloro reuse. IF SWALLOWED; Do not induce vomiting. Promptly drink

### a largo quant11y 01 milk, 

### egg whiles, gelatin solution or if these are nol available, drink large quantities of water. Avoid alcohol. Call 

### a physiCian immediataly. IF INHALED: Romoye Yidim to Irosh air, " not braathing, giye artllicial respiration. Administer oxygen 

### if nocGSS<1ry, Got mOdical atlenfion. 

# PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

# e CORROSIVE Causa:; eye and skin damage. 

### May be fall'll if absorbed through skin. Harmful 

### II swallowed or inhaled. Avoid breathing spray mist. Do not gel in eyes, on skin or on clolhing.**-Wear...fuJWGfl9th-UQI,j~~~Io'lec,** 

### and goggte; or faoo chiold**w~~~~iy.,-Wad:!.tlwr~aAdwaIGr af1~.bofot.Q-UIffig,** **~&mI)\,Ig** and**wa;~t3m~~~** Keep away fr(lm domestic animals. NOTE TO PHYSICtAN Thero is no spedfic antidofe, All treatment should be based on observed signs and symptoms of distress in the patient. Overexposure to materials other fhan this product may have occurred. Victims of seyere ovoroxp(lsure, by inhelation, should be kept undor modical obseNation for upto 72 hours lor dolayed onset of pulmonary edema. In a victim of ovor-expoSure by ingoslion, carolul gastric 13vago is rOQuifltd due

### to the possibility 01 stomach or esophagoal porforation. This material [s an acid, but usn of alkaline $ubstancos to neutrafi2:a it is contraindicatBd. 

## ENVIRONMENTAL HAZARDS Forterrestrial uses, do not apply dlrGCtIy to water, or to areas whom 5uriaco water is presont or 10 intertidal areas belowthe mean high water mark. Do not contaminate water when disposing of equipment washwalers. 

### Do not contaminate watnr used for irng3tion or domestic purposos. 

## USE PRECAUTIONS Do not apply PREpn. brand Ethephon through any typo of irrigation systom. Avoid spray drift 10 nearby crops as this product 

### wi!! cause modifICations in plant growth. P!antlnjury or reduced yields will result. 

### Do nof plant anofher crop within 30 days Oilier troatmon!. Mix only the amount of spray yOll axpoClto use 94ch day. Do not allow mixed solu1ion to stand overnight.


# 185

# •

DIRECTIONS FOR USE If fa a vlotation of Fedoral Law to use this product In a manner Inconsistent with Its labeling. Read enttre fabor boforo using this product.**R-i~RV** 

## STATEMION+ Mixors, 

### Ioad4ta <lAd 3jilplic&tono mUGl 'Noar a**lu~i&Id,-~roIOGorlS, Igng-&~~,-9IoIJ-.a~ro-avol~**  and eye GOnia", 3& per;sibl&. 00 not oRleH troated Ij.«I&**wiUli4-2~** alter appiicamm-unle&c**p~~~m.**

noteonIsminato water, 

### tcod, or feed by storago or disposal, oontainor is broken orcontents havo spifled, follow an precautions indicated' above and clean up immodiarofy. Bolero cleaning up. full length trousers, long sleoved shirt, protective gloves, and goggles or face shiold. Soak up spill with absorbent media such sand. oanh orother suitable material and disposeof waste at an approved wilste disposal tacility. 

### DISPOSAL j wastO$ arG acutely hazardous. Improperdisposalof oxcoss pGsticide, spray mixture, or rinsate is a lIiolalion of Fedoral law. theso wastes cannot be disposed 01 

### by use according to label instruclions, contact your Stato Pesticide or Environmental Control 

# '"g.,,,,>, ortho HazardousWast& representatille at the noarost EPA Regional Office lorguidance.



## GENERAL INFORMATION COTTON A folrar spray 01 PREpnt brand Efhephon Will accolerate opening of mature unopened cotton bolls and enhance detofiation which can result in oarrlOr harvest wHh an incmas&d recoverablo yiekl. PREplM brand Ethephon treatment on cOlton allows increased eltidoncy from a once-over harvest. TOBACCO (FLUE-CURED): A foliar spray at PREP1M brand Eth&phOn promolos early. uniform "yellowing" of mature tobacco. PREP"" roduces curing time, allowing mora efficienl use01 curing barn space, and increased control over harvest st::hedules. SPRAY PREPARATION Add 1.12 10 

### 3/4 01 tho roquiro-d amount 01 water to tho spray lank. Stan agilallon. Add Ihs required amount 

### of PAEpTI.! brand EthOphon, and the remaining amount of water. Prepare only as much spray solulion as can be usod on tho day 01 mixing. Do not allow spray solution to stand overnight. 00 not spill the concontrated producl on spray equipment, or any airplane parts, ANYSPillSSHOULD BE RINSED IMMEOIATELYW!TH PLENTYOFWATER.

• Useat a nurse**tan~** is highly rocommended for alloiding poSSible spiffs of concentraled lormuiation on spray equipment or any airpfano parts. TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES PREPn; brand Ethophon is compatible wilh OEF I

, FOLEX®, Oropp2, HalVade3

, Methyl Parathion, Guthiont, and Malathion4• PAEPfl.! may be appliod in soquence or as a tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable usa precautIOns and rale per acro rocommendahons on labels 01 products appHed astank mixlures or in sequence with PREP nI brand Ethephon. In some caSlls Slight reduction in boff opening rosponse has beon observed whon tank mixes with dofo/lants wore usod. 

## Good agitation in tho spray tank is Qssontial and a tank mixture·should not be alfowed to stand Without agitaHon lor more Ihan 5 to to minutes. Read and observe all appropriate labol usa diroctions and procautions lorthe detoliants and insecticides usod. NOTE: Undorconain conditions, lank mixtures 01 PREpn. brand Elhephon with desiocants conlaining sodium chlorale could resuff in the lormation ot hypochlorous acids which on heating win emit loxic chloride tumes. EaUIPMENT cLEANING Bocausa 01 tho acidic nature of thIS product, prOlonged e:.:pos-ura 10 spray deposit will damage acrylic plastics, certain painls, and mefals. Rinse thoroughly with a detergent and water all exposed acrylic plastic·type materials (e.g., aircraft windshields), and painlad surfaces wHhln an hour aftar expcsuro to spray deposits. At the end of each dey, rinse Ihoroughly with a dotergenl and water aff the melal parts of the aircratl and the associated spray equipment exposed to th9 spray doposits.



# 186

# • COTTON

EXPECTED PREpT" ONE SPRAY VOLUME 

### APPLICATION 

### USE CONDITIONS RATE GALLON (Gals/A) 

### TIMING PREP!).! 

### TREATS Plnta/A 

### LBS A.1. 

### Acros Ground 

### Air-· 

## PREpm Hot 

### andd"l

### aO"For 1 

### 113 1.0 

### 6 Apply whon the number of 

### Boll 

### Opanor· higher 

### mature unopened bolls is 

### Dry and

### 75 to 

### ao"F 2 1.5 

### 4 2·5 

### sufficient to produco !he 15 ·50 

### dosirod crop. SOQ belowfor Coo! but abovo ssaF 22/3 2.0 

### 3 

### lest 

### 01 boll 

### maturity. Treatment uniformly opens 

### 0' bolls 7 to 14 daysearlier. 

### Rank cotton PREpfl.! + High soil moisture ,/3 0.25 24 

### 15·50 5· 10 Apply 4 to 7 days prior to 

## FOLEX» 0' PREP"'" boll oponing 

### Oofollant Tank High fenility 

### love-I 

### application. To bo usod as 

### MIx a sequonlial treatmont wi1h, 

### 0, not in place- of PREPTM bol! Rank cotton 

### opening treatment. 

### PAEpN+ Cropp2 High soil moiSTure 1/3 

### 0.25 24 

### 10-50 

### 3 -to Apply 

### -4 to 7 days prior to 

### Oofollant 

### Tank High fOrlilily lovol PAEpTM boll opening 

### MIx Rank cotton application. To bo used as a sequ&ntial1re8tment with, not in place 01 PREPTM boll opening1raatment. Pro·Condltlonar 

### Hot. dry, above**80~F** 2/3 0.5 

### 12 Apply 

### 4 to 

### 7 days prior to 

### 10' Oofollatlon Cool, above**65~F** 11/3 1.0 6 15·50 2 ·5 dofolianl. Enhances top crop dalollation reducing m deterioration of bottom crop Rank cotton and allows lor earlier harvest. 

### ·Pl't:treatment With Defoliants Prior to PREPTM Boll Opening Treatment If the cotton isovorly rank or laying down in the middle. and goodspray coverage ot the bolls whh PREpm is dlfficun, a pretreatment with deloliants

### will

### be usatulto improve boll coverago with PREP,..., Usedosage ratos ot PREpm brand Ethophon recommended for boll opening. Read and observe all appropriate label usediroctions and precautions tor tha dalolianl usad. "In California and Arizona USQ a volume of no less Ihan 

### 5 galklns par'acre lor aerial applications. 

# e BoU Maturity A boll is matulewhon it is too hard to be dented when squeezed bOIWQen thumb and fingers, 100 hard to bo slicod with a sharp knile, and whon tho seed coat bocomes light brown in color. 

### Use Limitations Do not exceed a maximum 01 2.0 lb. afJA tor combined uses ot PREpTM per acrO per year. Boll Opening: 

### Do nOl1ank mix PREpN brand Elhephon with a desiccant it tho corlon is to be spindlo harvested, Pro·CondiTlon lor DeloliaTion: Do not tank mix PREpru wilh desiccants unloss plant desiccallon is requirod. 

### Do nOlose a defoliant belore there is suflicient maluro unopened bolls to producelhadesired yield {see Gunoral InformatiOn section on how 10 test tor boll maturiTy. 

### WHEN TO HARVEST COTTON 

### Do not harvest collon soonerthan 7 days alter a treatment with PREpn.. brand Elhophon, Observa the treated crop and harvest when optimum bon opoolng has boen reached. Too early haNest might reduce tho lulladvantage of the trealment and too lato a harvest may result in reduced quality and loSs 01 lint which wi!! drop Irom Ihe plant.



# 187

--_._-------

# • PREprn 

### Crop Sltuat/on Plnts/Acre

Directed Spray 1 1/3 

### Application

OVer·The·Top 1113-22/3 

### Application

USE lIMITATtONS 

# TOBACCO (Flue-Cured Only)
Spray Volume Gallonsl Spociflc 

### Directions



### Acro 50·60 Uso drop nozzles. Chooso TG or OC spray lipS designed 

### to apply SO • 60 

### gpa at 35··10 P" 

### aod at tractor speed 

### of 

### 2·3 mph. 

## U" 2 nozzles por row; one on each skle 01 the row droppod low anough to direct tho spray to tho loavos to be ripaned and harvostod. Thorough spray coverage is essential. 

### With a directed spray, be sure to harvest all loaves 

### with 20% 

### ormor. yo/lowinq. 40-60 Treat only when leaves remaining on the stalk are maturo. To onsure remaining loaves are maluro, test spray sovoral tobacco plants as described underthe section ·Proper Timo 01 Treatmont: Usethe lower rate in a normally mature cropwhon experience indicates that minimum ripening inducement 

### is roquirod. Uso the higher rate when the crop is heavy and has 

### a tendency 

### to be more rank or when temperatures are lower than normal. Always test spray to dotermine 

### if the tobacco is mature enough to rospond totreatment with PAEpn.I brand EI hephon

. Apply over-the-lop PAEplM brand Ethophon spray 

### as a line mist using three nozzlos (one nozzlo tips over the center ot the plant, and one on each skle) so all leaves aro covered thoroughly, similar to the application pattern ot systemic sucker conlrol agonts. Use 

### a spray pressure ot 

### 40 to GO'psi.

Do not 

### apply PAEpN brand Ethephon to immature loaves 

### as thiS can result in unsatistaclory coloring, weight loss and roduced loa! quality. 

### Do not allow Ihocrop to ovor ripon In the hold aftor using PAEf'ThI brand Ethephon, since this maycauso some reduction in yield and quality. Do not treat botora anticipated major Slorm which could provent harvast and rnull in crop loss. Do not apply PAEf>1l< brand Ethephon if rain is expected withm 4 hours. APPLICATION TtMtNG SlliX:eMlul results with PREpTM call tor troatmont when leaves aro maturo, not overly rank groon when sprayed. To easily dotermine the prop.ir Iroatmant timing and the numberot loaves per slalk ready for harvest, lOst spray sevaral plants in moro than on& location in each 

### Hald and obsefVo the response. Mature loaves will begin to yallow in 

### 24 to 

### 72 hours. Test loavesthat tail toyellow in 

### 72 hours are not mature and are not roady for PREpno brand Elhephon treatment. Wait 

### a taw days to permit further nalural maturing, thon make anolher tast spray or "maturity" chacko

• Whon you havo confirmed Ihe number of leaves per plant that will color. you can dolermin(il the number 

### 01 acres to treat in order to Iill the barn. Prepare your tost $pray 

### by mixing OnG teaspoon ot PREP'" in t quart

## 01 water. Spray each test plant With about t oz. ot this mlxlure, covering aU leaves with a lino mist.**PAEP~** brand Ethephon will not color immature sprayed leaves. WHEN TO HARVEST All maturo, sprayed leavos will txlgin to colorwithin 

### 24 to 

### 72 haUlS alter PREP'" brand Ethephon application. The yellowing process is weather dopendont; cool weathfuwiO delay. while hot. sunny weather can speod up the process. HaNost troated tobacco when loaves have reachod thO' desired color intensity. Do not allow tobacco to become over ripe boloro slarting harvost. leat dropcan occur when tobaceo is over flpO and lell on the stalk. II 

### a numberot tha bottom loaves hava yallowed at tho time ot treatmenl. thoy should be harvestod prior to spraying with PREP'" brand Ethephon. With an over-the-top application, harvesting can commence 

### 24 hOurs atter PAEprn brand Ethephon application dOp.inding on weather conditions orto avoid over ripe tobacco. Tobacco harvested 

### 24 hours aliertrealment will require more time in the coloring phase

### 01 the curing ptocess. CURING PREp-rn TREATED TOBACCO Curing procedures are as much an art as a science and each cure must be judgedon the basis otlobaceo condition, interval between troalment and harvos!. woather and type 

### 01 curing tacility beton) prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must bo taken to obsolVe and control the cUring process closely, especially during the late "coloring" and early**~drylng·** slagos 

### 01 the lea!. PREpN brand Ethephon treated tobacco will have started tho !Xlloring processwhon harvested. reducing the limo required in the coloring phase

### 01 curing. Troated tobacco should be driod taster. 

### If tobacco leaves are green oroontaln some green when harvested, it may 

### be nocessary to colorthom tor a few hOurs. 

### II the leaves are completely yellow, temparature and ventilation must be adjusted in a mannerto dry the tobacco as tast as possiblo without scalding. Onca the leal is dried {3/4 dry}, you should tollow normal procodures lor curing. Sinco PAEPr.I brand Ethephontteated leaves cure laster. treated and untreated leave$. should not bocured together In the samo bam. 

# 188

### ·
.....**-~--------**



# LIMITED WARRANTY AND DISCLAIMER Tho manutacturor warrants (a) that this product conlorms to tho chomical description on Iho labol: (b) that this product is roasonably 

### tit lor tha purposes set lorth in tho directions for use whon 

### it is used in accordance with such directions; and (c) that tho directions. warning and olhar statomonts on this labol aro basad upon responsiblo exports' evaluation 01 reasonable tosts 01 olfoctivonoss, 01 toxicity to laboratory animals and to plants, and 01 residues on food crops and upon reports 01 flold experience. Tosts have not been 

### made on all varieties or in all slates or undorall conditions. THE MANUFACTURER NEITHER MAKES NOR INTENDS, NOR DOES IT AUTHORIZE ANY AGENT OR REPRESENTATIVE TO MAKE, ANY OTHER WARRANTIES, EXPRESS OR IMPLIED, AND IT EXPRESSLVEXCLUDES AND DISCLAIMS ALL IMPLIED WARRANTIES OF MERCHANT·ABILITY OR FITNESS FOR A PARTICUlAR PURPOSE. THIS WARRANTY DOES NOT EXTEND TO, AND THE BUYER SHALL BE SOLELY RESPONSIBLE FOR, ANY AND ALL LOSS OR DAMAGE WHICH RESULTS FROM THE USE OF THIS PRODUCT IN ANY MANNER WHICH IS INCONSISTENTWITH THE LABEL DIRECTIONS, WARNINGS OR CAUTIONS. BUYER'S EXCLUSIVE REMEDY AND MANUFACTURER'S OR SELLER'S EXCLUSIVE LIABILITY FOR ANY AND ALL CLAIMS, LOSSES, DAMAGES, OR INJURIES RESULnNGFROMTHE USE OR HANDLING OF THIS PRODUCT, WHETHER OR NOT BASED IN CONTRACT. NEGLIGENCE, STRICT LIABILITY IN TORT OROTHERWISE SHALL BE LIMITED. ATTHE MANUFACTURER'S OPTION, TO REPLACEMENTOF, OR THE REPAYMENT OF THE PURCHASE PRICE FOR. THE QUANTITY OF PRODUCTWmt RESPECTTO WHICH DAMAGES ARE CLAIMED. IN NO EVENT SHALL MANUFACTURER OR SELLER BE LIABLE FOR SPECIAL, INDIRECT OR CONSEOUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

### NOTICE TO BUYER 

### Purchaso 01 this produCl dOllS not canlor any rights under palients goyorning this prodUcl 

### or tho use therool in countries outsido 01 tho Uniled Stales.

-. !OEF and Guthion aro roglstOioo trademarks 01 Bayer AG. Germany. 2Dropp 

### is a rogtslerod tfademark 

### 01 NOR·AM Chemical Company. 3HarvMe is a registofed trademark 01 Uniroyal Company.



# • 4Malathion is 

### a. trademark ofAmerican Cyanamid Company,

Roone-Poutone Ag Company P.O. Box t20t4. 2 TW. Alexander Drive RO$oarch Triangle Park, North Carolina 27709 PREP is Ihotrademark of Rhone-Pou/onc, FOLEX is a regislered Illldemark01 Rhone-Poulenc. PREprv brand Ethophon lor Cotton and Tobacco (MASTER) Notilication 6/9193.


# 189

# •

• UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20460



## Warren A. Davis 

## Senior Registration Manager Rhone-Poulenc Ag Company P.O. Box 12014 

## 2 'r.N. Alexander Drive Research Triangle Park, NC 27709



## Dear Mr. Davis: SUBJECT: Review of Alternate Formulation PREP® Plant Regulator for Cotton EPA Reg. No. 264-418 Your Letter Dated 11/19/93 OfrlCE Of PflEVENTION. P£SltcIUfSM{l) TOXIC SUBSTANCES



## 'rhere is no objection to the use of the alternate formula-tion (CSF) dated 11/19/93 that was requested in your letter of the same 

## date. The amendment has been inserted in the file for the subject product. If you have any questions, please contact Terri stowe of 

## my staff at (703) 305

- 6117

. 

## Sincerely yours,

Cynthia Giles-Parker Product Manager (22) Fungicide-Herbicide Branch Registration Division (7505C)

# •

• REG.

## NO:~!~'I/

# y ALE SYMBOL:

____ __

PRODUcr CHEMISTRY REVIEW FOR END USE PRODUcrS


## TO: PM 

# c2;;>-

FROM:

# r IH.s-l-o,!

THRU: 

# -/:b..iJi:lli.. PRODUcr 

## NAMES: 

# Bft? fYhlf 

# !?sec/Mer hW G.J-fr:;"

.

CHEMICAL:...:-

_______ _**~** 

## NOS.

__________________ _**NonF~** 

# Uu.

__**~~~_·**

# ______

__ lnerts cleared: c () d () e () yes () no ( ) 

## lnerts List I () 

## Other ( )


## Please provide the 

## requesu:d infonnation for the 

## following checked items:



## I. 

# (1 Submit the 

## prodoct specific 

## prodoct chemistry data 

## for your 

## prodoCl. ( 

# I If submined earlier, 

## provide**~** 

## Numbet(s). {} Your 

## prodoct is 

## not sufficiently similar 

## to the 

## prodoct your 

## referenced.
2. 

## In re{e",nce to the 

## Confidential Statement of Fomnda (CSP), 

# please provide the 

## following: (1 

## a) 

## pH ofprodoct at • 

## specified water 

## dilution. [J b) 

### Density 

## ofproduct.
[ ) 0) 

## FWb point 

## ofprodoct.



# [J d) 

## FWb point 

## of

## product 

## with propellent

.. 

## per item #6(q) 

## or item #S(c). 

## [1 e) Flash extension of product including flashbacks ifnoted.

L,;'J 

# fiLeJLt'

191

# --------------_

....



# _ ...



### 3. 

## -2-

[] f) 

### The 

## upper and lower certified 

### limits based on the pure active ing=:ients rather 

## !han 

## the technical or concentrate,


### [] g) The upper and lower certified limits of the individually added inerts. 

# [J h) 

# [J i) 

## [] j)

Based on the 

# =nt CSF 

# dated,,-_=

__ -:---:-' your product 

## will not meet 

### the label claim for the active ingredient. Please "'vise the label or the CSF so dill the 

## infonnation agrees.
4. Provide the cbemicaI identify of all components, the percenta&e 

### composili<hl, CAS Registry Number, and Material Safety Data S_ (two 

## copia) for the following compounds:


### l. 

# 2.
3.
4.


## 5.

The supplier may cootact 

### EPA

# _y refe!101lcing the File Symbol of EPA Registration Number 

## in 

## their 

## response. For 

## <!yeo, provide the color 

## index and CAS Registry Numbers for 

## all componenu. For perfumeo 

## and llavorinp, 

## provided for each compoDOIII 

## in the mixtute: the 

## <bemical natt1e. 

### CAS Regisuy 

### Number, and the 

# percemap or """" 

## in percenta8e in the mixture. Certify 

## that flavors

.... non-food 

## type. 

# The ('nnfidentj,J 

### infonnation submitted by 

## the supplierl 

## it 

## kept confidential 

## under 

## FIPRA Section 10.

5. 

## In the proposed labeling, provide the following infonnation:
[] a) Update the label Storage and Pesticide and Container Dupo

.. 1 Statements in acconlmce with [ ] 

### PR Notice 84-1 for non-ICJOIOI OODIainers for houses and institutional ""'. of [ ] PR Notice 83-3 for 

## all other uses.



# 192 

# •

•

# • ·3-
[1 b) Add the 

## hea<fing PHYSICAL OR CHEMICAL HAZARDS to the label and the 

## appropriate statement per 

## 40 CFR 

## IS6.1O(hX2Xili).
[1 c) 

## Under the heading PHYSICAL OR CHEMICAL HAZARDS. listthe product
as extremely Flammable (because your product contains flammable 

## propellents). [] d) Provide 

## that the solvent does not have insecticidal acnVlty, 

## it should 

## be removed from the ingredient statement active ingredient listing 

## and the percentage 

## added to 

## the inen ingredients. 

## If the 

## solvent has insecticidal 

## .propertie.s. provide the EPA Registration Number. 

# [1 e) Add 

## a foomote to the inert ingredients indicating: Contains



## [ 1 f) 

## Since your dara matrix 

## does not provide 

## a dielecttical 

## b£eUdown voltage. you must add the following statement 

## <0 the physical or Chemical Hazards 

## heading;
Do 

## not use 

## this product in 

## or on 

## electrical 

## equipment due to 

## the poasibilily of shock 

## bawd.
[1 g) 

## The tertns active ingredicnt(s) 

## and inert ingredients should 

## be in 

## the same type 

## size, be aligned to the 

## same margin and 

## be 

## equally prominent. [1 h) 

# [1 i)



## •
. 6. 

## In 

## tefcnonce to the product 

## specific dara 

## require_. provide the following 

## infoanation: [1 0) 

## S_ of Composition: A 

## complete descriptioa of the manofacturing fommlatina 

## proc:eu. Describe equipment used. mixing time. temperature. 

## ptellwe. ere. [1 b) 

## Oiacnssion ofFormation ofUnintentional Ingredients: A brief description of 

## impurities formed during the manofacturing/fonnulation 

## proc:eu. inpackaging
or 

## during storoge. 

## If you do not expect any 

## impurities during 

## these stages. 

## please so stale. 

## [1 c) Certification of Limits: Upper and lower limits or each active and 

## individually 

## added inen 

## component.



# 193

# ---------_

.....

# _ ...



# [J d) 

## Ana1ytico1 Method: Provide the methods used to 

### analyze for the active ingredien.. or a 

## full reference for a published method or 

## MRJD Number(s) 

# (J e) Color: In 

## conunon terms, 

# [J f) 

### Physical State: e.g
.. solid. liquid, pressurized liquid. etc.
[] g) Odor: 

### In common terms 

## [J h) 

### Density: e.g
.. Ibslgallon for liquid! or IbS/cu.ft for solid3. 

# [J i) 

## Ph: Provide 

## pH ofproduct or 

## pH of a specified water dilution. 

# [J j) 

## Oxidizing or 

## Reducing Action: 

## Note these 

## _.rimes. 

## ifany. [J k) Explodability: Note these characteristics, 

## ifany. 

# [1 I) Viscosity: Can 

## be expressed in centipoise or cenristob. 

## [1 m) Miscibility: Note these characteristics 

## ifproduct 

## is an emulsifiable 

## liquid and 

### mixed 

## with oil. 

# [1 n) 

## Corrosion Olara<:teristics: 

## This inf01IIl8lion can 

## be llOIed during 

## !be storage stability 

## study. 

## [1 0) 

## Dielectric 

## Breakdown Voltage: For products 

## used

.... eIecIrical 

## equlpmem. [1 p) 

## Storage Stability: 

## The formulated product 

## inust be malyzed for 

## i1s ac:rlve 

## ingIedients 81 

## time 

# zero and during 

# one yar of

## storage. 

## The storage 

## ahouId 

# •

be at 

## warehouse conditions of riollpelatute 

## and humidity and 

## Slond in 

## !be • 

## product's 

## COIIIlt>m:iJol 

## ptickage. NOie: For !be storage 

## stability 

## study, you 

## may not 

## reference !be data on 

## source product coocolllrldle you sre using to 

## formul_ 

## your product.


## [J 

## q)**~:** 

## FIIIJh poinl/flame extension. 

## The 

## flllJh pow 

## "'P""<d exceeds !be one expected for 

## this product. 

## PI...., cbeck 

## and resubmit. 

## Mixtures IIIIIRted under 

## pressure, including tho

.. containing hydrocalboo.s, are subject 

## ill 

## tbeir esrtirety to

..... 

## indicated in 

## 40 CPR 

## Section 1S6.IO(h)(2)(ili) ofthe 

## 11IUipactage. Note that flash poin

.. for pressurized 

## liquid from 

## !be container 

# [1 ifany of 

## !be items are not applicable. write N.A. 

## and explain reasons are specified 

## uoder chemistI)' data requirements [OOttlo,"'. 

## See 40 CPR Pan 158.



# 194

# •

• -5-
7, 

# [J The following 

## is the regulatory status of the inert 

### ingredients 

## under 40 CFR 180.1001 for for the exemption of the requirement of a tolerance. 8, Other



## Note to 

## PM: Inter-office use only



## SUMMARY ATIACHED



# 195

..**----~-** 

### ..

## -----------

### ..at

11-1
41-1
U-l

U-l
U-t
U-l

U-l 

# • u-,

U-4
U·S
U-I
U-7**U~.** 

# U-'

U-10
U-11

n

..u: 

### U-U


## u-u 

# • fl-U f.,_U
U-11
U-U
fl-1'
U-20
U-U 

# -

'l'JUIU 1:

."... 

# II 

# _ ...**n~**

### ... u-ut:y .-d.**~.u:.t_** (400'k1S'.ln. lCO, lU, lU. 1n)**,~c~** !a.t\tUy , pu
.. J.

... U. ot Iaqr..t.L.au

::••".,1ptlotl

..

### t St&n::I...II4' u.tNul. , KuI.f•• tlUta

..**,~**•••
1a.oU••1

.... ct r

.. _tJ.

..a 1ft :"I"U,U .•• _L.. f1-....u, d.I

..... CurtU!._u.- ot**~ ~**  (40Cftl.$1:.1'70, 11•• 110)**rul~azy** ........

## ,..:UO ot 'Pdl/;Clt hllpl_

CU1:J..U44UOll of**~...u**

### .. t 

### w..ut. AIoaJ.yti-.J.**~Iloda** t. VuifY e-.rtJ.u-..t t.a.1U


# - ... a..L-.J. <lIII

....**~_ (~,UO)** **~,.. '1t~J.-.I.**  ltat. 

# ""'-

tt.J.tU4'

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IoUill<r '_Lat;**o-..J,.~.** klJr. c....!.cy. '"'

.. ...ttb ¢II:.-r1t'

..

1

....LUt1 

# ._**r.-.~. O~t1.oa**  

### eo...-t 0du0l/1f&t;_ '!IoIftJ.i:J.ooIt, Co&ffio,i,Mt



# .. ftUJ.LUty



# .........

# -
...

# -**r~UJ,t;7** 

### w.

..



# ... ....=
'Iu_i..?



# ...........**~Q,q",,,,~ l)~**  ......d_ Volu.. 

# "**-~l.** • • 1fU--'**~J.~,**____________________ __
lIlA.

- Hot Il'PU-.bt. OC

- Ou

.. 

### eq. s:.etio

.. --..., ____________________ _ 

## 0..".:



# 196

## DP BARCODE: 0196865 CASE: 003396 DATA PACKAGE RECORD DATE: 11/19/93 SUBMISSION: 8453597 BEAN SHEET 

### page 1 

### of 1 

# * * * CASE/SUBMISSION INFORMATION ok 

# * 

# *

ACTION: 346 

## RESUBMISSI0N 

## CASE TYPE: REGISTRATION CHEl1ICALS: 099801 Ethephon 55.4000%
10#: 000264-00418 PREP PLANT REGULATOR 

## C011PANY: 000264 RHONE-PCULENC AG COMPANY PRODUCT MANAGER: 22 CYNTHIA GILES-PARKER PM TEAM REVIEWER: TERRI STOWE FOR COTTON
703-305-5540 703-305-7381 

## 02/17/94 ROOM: CM2 ROOM: CM2 RECEIVED DATE: 11/19/93 DUE OUT DATE: 

# * * * DATA PACKAGE INFORMATION 

# * * *
DP BARCODE: 196865 EXPEDITE: Y DATE SENT: 11/19/93 DA'rE RET.: / 

## CHEMICAL: 099801 Ethephon**~** 

## TYPE: 001 SUbmission Related Data Package CSF: Y 

## LABEL: N ,:c;,;;;,:cTO DATE IN DATE OUT 

## / / / 

## / ADMIN DUE NEGOT



## PROJ DATE: DATE: 01/03/94 01/03/94 

## / / / / / / DATE: 

## / / / 

## / REVR: // // CONTR: / / / /



## DP BC 

# * * 

# * DATA REVIEW INSTRUCTIONS 

# * * *

Per attached 04/20/93 review, the alternate CSF dated 02/01/93 could not be accepted until the EPA Reg. No. for the source was corrected/accepted on the BASIC esp. The BASIC CSF vIas 

## accepted per the attached 10/29/93 review. Please review the alternate CSF to see if 

## it is now acceptable. The registrant has requested an expedited review. I 

## am 

## sorry if this has inconvenience you, but another PM 22 Team reviewer handled the follow-up (BASIC CSF) and I was unable to fol,low-up on tl)e alternate reviews. If you have any questions, please call me at 305

- 6117. THANK YOU! ! 

## ! 

# * * * DATA PACKAGE EVALUATION 

# * 

# * *
No evaluation is written for this data package.



# * 

# * * ADDITIONAL DATA PACKAGES .FOR THIS SUBMISSION 

# * * I< 

## BRANCH/SECTION DATE OUT 

## DUE BACK INS CSF



# 197 229 261



## /

LABEL