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SECTION 1. PRODUCT AND COMPANY IDENTIFICATION 

Product name : Solstice® N-13 

MSDS Number : 000000016417 

Product Use Description : Refrigerant

Manufacturer or supplier's 

details 

: Honeywell International, Inc. 

101 Columbia Road 

Morristown, NJ 07962-1057 

For more information call : 800-522-8001 

+1-973-455-6300 

 (Monday-Friday, 9:00am-5:00pm) 

In case of emergency call : Medical: 1-800-498-5701 or +1-303-389-1414 

: Transportation (CHEMTREC): 1-800-424-9300 or +1-703-

527-3887 

: 

 : (24 hours/day, 7 days/week) 

SECTION 2. HAZARDS IDENTIFICATION 

Emergency Overview 

Form : Liquefied gas 

Color : clear and colourless 

Odor : slight ether-like 

Classification of the substance or mixture 

Classification of the 

substance or mixture 

: Gases under pressure, Liquefied gas 

Simple Asphyxiant 

GHS Label elements, including precautionary statements 
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Symbol(s) : 

Signal word : Warning 

Hazard statements : Contains gas under pressure; may explode if heated. 

May displace oxygen and cause rapid suffocation. 

Precautionary statements : Prevention: 

Use personal protective equipment as required. 

Storage: 

Protect from sunlight. Store in a well-ventilated place. 

Hazards not otherwise 

classified 

: May cause frostbite. 

May cause cardiac arrhythmia. 

May cause eye and skin irritation. 

Carcinogenicity 

No component of this product present at levels greater than or equal to 0.1% is identified as a known 

or anticipated carcinogen by NTP, IARC, or OSHA. 

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS 

Chemical nature : Mixture 

Chemical Name CAS-No. Concentration 

trans-1,3,3,3-Tetrafluoroprop-1-ene 29118-24-9 58.00% 

1,1,1,2-Tetrafluoroethane 811-97-2 42.00% 

SECTION 4. FIRST AID MEASURES 
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Inhalation : Remove to fresh air. If breathing is irregular or stopped, 

administer artificial respiration. Use oxygen as required, 

provided a qualified operator is present. Call a physician. 

Skin contact : Rapid evapouration of the liquid may cause frostbite. If there is 

evidence of frostbite, bathe (do not rub) with lukewarm (not 

hot) water. If water is not available, cover with a clean, soft 

cloth or similar covering. Call a physician if irritation develops 

or persists. 

Eye contact : Rinse immediately with plenty of water, also under the eyelids, 

for at least 15 minutes. In case of frostbite water should be 

lukewarm, not hot. If symptoms persist, call a physician. 

Ingestion : Unlikely route of exposure. As this product is a gas, refer to the 

inhalation section. Do not induce vomiting without medical 

advice. Call a physician immediately. 

Notes to physician 

Treatment : Treat frost-bitten areas as needed. 

SECTION 5. FIREFIGHTING MEASURES 

Suitable extinguishing media : The product is not flammable. 

Use water spray, alcohol-resistant foam, dry chemical or 

carbon dioxide. 

Use extinguishing measures that are appropriate to local 

circumstances and the surrounding environment. 

Specific hazards during 

firefighting 

: Contents under pressure. 

This product is not flammable at ambient temperatures and 

atmospheric pressure. 

However, this material can ignite when mixed with air under 

pressure and exposed to strong ignition sources. 

Container may rupture on heating. 

Cool closed containers exposed to fire with water spray. 

Do not allow run-off from fire fighting to enter drains or water 

courses. 

Vapours are heavier than air and can cause suffocation by 

reducing oxygen available for breathing. 

In case of fire hazardous decomposition products may be 

produced such as: 
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Hydrogen fluoride 

Carbon monoxide 

Carbon dioxide (CO2) 

Carbonyl halides 

Special protective equipment 

for firefighters 

: In the event of fire and/or explosion do not breathe fumes. 

Wear self-contained breathing apparatus and protective suit. 

No unprotected exposed skin areas. 

Exposure to decomposition products may be a hazard to 

health. 

SECTION 6. ACCIDENTAL RELEASE MEASURES 

Personal precautions : Immediately evacuate personnel to safe areas.

Keep people away from and upwind of spill/leak.

Wear personal protective equipment. Unprotected persons 

must be kept away.

Remove all sources of ignition.

Avoid skin contact with leaking liquid (danger of frostbite).

Ventilate the area.

After release, disperses into the air.

Vapours are heavier than air and can cause suffocation by 

reducing oxygen available for breathing.

Avoid accumulation of vapours in low areas.

Unprotected personnel should not return until air has been 

tested and determined safe.

Ensure that the oxygen content is >= 19.5%.

Environmental precautions : Prevent further leakage or spillage if safe to do so.

The product evapourates readily.

Methods for cleaning up : Ventilate the area.

Allow to evapourate.

SECTION 7. HANDLING AND STORAGE 

Handling 

Handling : Handle with care.

Avoid inhalation of vapour or mist.
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Do not get in eyes, on skin, or on clothing.

Wear personal protective equipment.

Pressurized container. Protect from sunlight and do not expose 

to temperatures exceeding 50 °C.

Follow all standard safety precautions for handling and use of 

compressed gas cylinders.

Use authorized cylinders only.

Protect cylinders from physical damage.

Do not puncture or drop cylinders, expose them to open flame 

or excessive heat.

Do not pierce or burn, even after use. Do not spray on a naked 

flame or any incandescent material.

Do not remove screw cap until immediately ready for use.

Always replace cap after use.

Advice on protection 

against fire and explosion 

: Do not spray on a naked flame or any incandescent material.

Keep away from direct sunlight.

Fire or intense heat may cause violent rupture of packages.

Vapours may form explosive mixtures with air.

The product is not easily combustible.

Storage 

Requirements for storage 

areas and containers 

: Keep containers tightly closed in a cool, well-ventilated place.

Keep away from direct sunlight.

Further information on 

storage conditions 

: Keep only in the original container at temperature not 

exceeding 50°C

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Protective measures : Do not breathe vapour.

Avoid contact with skin, eyes and clothing.

Ensure that eyewash stations and safety showers are close to 

the workstation location.

Engineering measures : General room ventilation is adequate for storage and handling.

Perform filling operations only at stations with exhaust 

ventilation facilities.

Eye protection : Wear as appropriate:
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Safety glasses with side-shields

If splashes are likely to occur, wear:

Goggles or face shield, giving complete protection to eyes

Hand protection : Leather gloves

In case of contact through splashing:

Protective gloves

Neoprene gloves

Polyvinyl alcohol or nitrile- butyl-rubber gloves

Skin and body protection : Avoid skin contact with leaking liquid (danger of frostbite).

Wear cold insulating gloves/ face shield/ eye protection.

Respiratory protection : In case of insufficient ventilation, wear suitable respiratory 

equipment.

Wear a positive-pressure supplied-air respirator.

Vapours are heavier than air and can cause suffocation by 

reducing oxygen available for breathing.

For rescue and maintenance work in storage tanks use selfcontained breathing apparatus.

Hygiene measures : Handle in accordance with good industrial hygiene and safety 

practice.

Ensure adequate ventilation, especially in confined areas.

Do not breathe vapour.

Avoid contact with skin, eyes and clothing.

Remove and wash contaminated clothing before re-use.

Keep working clothes separately.

Exposure Guidelines

Components CAS-No. Value Control 

parameters 

Upda

te 

Basis 

trans-1,3,3,3-

Tetrafluoroprop1-ene 

29118-24-9 TWA :

time 

weighted 

average 

(800 ppm) 2012 WEEL:US. AIHA 

Workplace 

Environmental 

Exposure Level 

(WEEL) Guides

trans-1,3,3,3-

Tetrafluoroprop1-ene 

29118-24-9 TWA :

time 

weighted 

average 

(800 ppm) 31.03.

11

Honeywell:Limit 

established by 

Honeywell 

International Inc.
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1,1,1,2-

Tetrafluoroethane 

811-97-2 TWA :

time 

weighted 

average 

(1,000 ppm) Honeywell:Limit 

established by 

Honeywell 

International Inc.

1,1,1,2-

Tetrafluoroethane 

811-97-2 TWA :

time 

weighted 

average 

4,240 mg/m3 

(1,000 ppm) 

2007 WEEL:US. AIHA 

Workplace 

Environmental 

Exposure Level 

(WEEL) Guides

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES 

Physical state : Liquefied gas

Color : clear and colourless 

Odor : slight ether-like 

Boiling point/boiling range : Note: not determined 

Flash point : Note: not applicable 

Lower explosion limit : Note: not applicable 

Upper explosion limit : Note: not applicable 

Vapor pressure : 554 kPa 

at 20 °C(68 °F) 

 1,389 kPa 

at 54.4 °C(129.9 °F) 

Density : Note: not determined 
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Ignition temperature : Note: no data available 

Decomposition temperature : > 250 °C 

Note: Decomposition temperature, To avoid thermal 

decomposition, do not overheat. 

SECTION 10. STABILITY AND REACTIVITY 

Chemical stability : Stable under normal conditions. 

Possibility of hazardous 

reactions 

: Hazardous polymerisation does not occur. 

Conditions to avoid : Pressurized container. Protect from sunlight and do not 

expose to temperatures exceeding 50 °C. 

Can form a combustible mixture with air at pressures above 

atmospheric pressure. 

Do not mix with oxygen or air above atmospheric pressure. 

Incompatible materials to 

avoid 

: Finely divided aluminium 

Potassium 

Calcium 

Powdered metals 

Aluminium 

Magnesium 

Zinc 

Hazardous decomposition 

products 

: In case of fire hazardous decomposition products may be 

produced such as: 

Hydrogen fluoride 

Carbon monoxide 

Carbon dioxide (CO2) 

Carbonyl halides 
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SECTION 11. TOXICOLOGICAL INFORMATION 

Acute inhalation toxicity

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: 100000 ppm 

Species: mouse 

Note: Acute (4-Hour) Inhalation Toxicity Screening Study 

(mouse): No lethality at >100,000 ppm. 

 LC50: > 207000 ppm 

Exposure time: 4 h 

Species: rat 

1,1,1,2-Tetrafluoroethane : LC50: > 500000 ppm 

Exposure time: 4 h 

Species: rat 

Skin irritation

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Species: rabbit 

Result: No skin irritation 

Method: OECD Test Guideline 404 

Sensitisation

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Cardiac sensitization 

Species: dogs 

Note: Did not cause sensitisation on laboratory animals. 

1,1,1,2-Tetrafluoroethane : Cardiac sensitization 

Species: dogs 

Note: No-observed-effect level 

50 000 ppm 

Lowest observable effect level 

75 000 ppm 

Repeated dose toxicity

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Species: rat 

Application Route: Inhalation 

Exposure time: (13 Weeks) 

NOEL: 5000 ppm 

Causes mild effects on the heart. 
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1,1,1,2-Tetrafluoroethane : Species: rat 

NOEL: 40000 ppm 

Genotoxicity in vitro

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Test Method: Chromosome aberration test in vitro 

Cell type: Human lymphocytes 

Result: negative 

1,1,1,2-Tetrafluoroethane : Note: In vitro tests did not show mutagenic effects 

 : Test Method: Ames test 

Result: negative 

Genotoxicity in vivo

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Test Method: Mutagenicity (in vivo mammalian bone-marrow 

cytogenetic test, chromosomal analysis) 

Species: mouse 

Cell type: Micronucleus 

Application Route: Inhalation 

Result: negative 

Teratogenicity

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Species: rabbit 

Method: Prenatal Developmental Inhalation Toxicity Study 

Note: Did not show teratogenic effects in animal experiments. 

 Species: rat 

Method: Prenatal Developmental Inhalation Toxicity Study 

Note: Did not show teratogenic effects in animal experiments. 

Further information : Note: May cause cardiac arrhythmia.

SECTION 12. ECOLOGICAL INFORMATION 

Toxicity to fish 
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trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: NOEC: > 117 mg/l 

Exposure time: 96 h 

Species: Cyprinus carpio (Carp) 

Toxicity to daphnia and other aquatic invertebrates 

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: EC50: > 160 mg/l 

Exposure time: 48 h 

Species: Daphnia magna (Water flea) 

Toxicity to algae 

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: Growth inhibition 

NOEC: > 170 mg/l 

Exposure time: 72 h 

Species: Algae 

Biodegradability 

trans-1,3,3,3-

Tetrafluoroprop-1-ene 

: aerobic 

Result: Not readily biodegradable. 

Further information on ecology 

Additional ecological information 

1,1,1,2-Tetrafluoroethane : Accumulation in aquatic organisms is unlikely. 

This product contains greenhouse gases which may 

contribute to global warming. Do NOT vent to the atmosphere. 

To comply with provisions of the U.S. Clean Air Act, any 

residual must be recovered. 

SECTION 13. DISPOSAL CONSIDERATIONS 

Disposal methods : Observe all Federal, State, and Local Environmental 

regulations. 

SECTION 14. TRANSPORT INFORMATION 

DOT UN/ID No. : UN 3163

Proper shipping name : LIQUEFIED GAS, N.O.S. 
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(trans-1,3,3,3-Tetrafluoroprop-1-ene, 1,1,1,2-

Tetrafluoroethane) 

Class 2.2 

Packing group 

Hazard Labels 2.2

IATA UN/ID No. : UN 3163 

Description of the goods : LIQUEFIED GAS, N.O.S. 

 (trans-1,3,3,3-Tetrafluoroprop-1-ene, 1,1,1,2-

Tetrafluoroethane) 

Class : 2.2 

Hazard Labels : 2.2 

Packing instruction (cargo 

aircraft) 

: 200 

Packing instruction 

(passenger aircraft) 

: 200 

IMDG UN/ID No. : UN 3163 

Description of the goods : LIQUEFIED GAS, N.O.S. 

 (TRANS-1,3,3,3-TETRAFLUOROPROP-1-ENE, 

1,1,1,2-TETRAFLUOROETHANE) 

Class : 2.2 

Hazard Labels : 2.2 

EmS Number : F-C, S-V 

Marine pollutant : no 

SECTION 15. REGULATORY INFORMATION 

Inventories 

US. Toxic Substances 

Control Act 

: On TSCA Inventory 

Australia. Industrial 

Chemical (Notification and 

Assessment) Act 

: Not in compliance with the inventory 

: trans-1,3,3,3-Tetrafluoroprop-1-

ene 

29118-24-9 

Canada. Canadian 

Environmental Protection 

Act (CEPA). Domestic 

: All components of this product are on the Canadian DSL. 
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Substances List (DSL) 

Japan. Kashin-Hou Law 

List 

: On the inventory, or in compliance with the inventory 

Korea. Toxic Chemical 

Control Law (TCCL) List 

: On the inventory, or in compliance with the inventory 

Philippines. The Toxic 

Substances and Hazardous 

and Nuclear Waste Control 

Act 

: Not in compliance with the inventory 

: trans-1,3,3,3-Tetrafluoroprop-1-

ene 

29118-24-9 

China. Inventory of Existing 

Chemical Substances 

: On the inventory, or in compliance with the inventory 

New Zealand. Inventory of 

Chemicals (NZIoC), as 

published by ERMA New 

Zealand 

: Not in compliance with the inventory 

: trans-1,3,3,3-Tetrafluoroprop-1-

ene 

29118-24-9 

National regulatory information 

SARA 302 Components : SARA 302: No chemicals in this material are subject to the 

reporting requirements of SARA Title III, Section 302. 

SARA 313 Components : SARA 313: This material does not contain any chemical 

components with known CAS numbers that exceed the 

threshold (De Minimis) reporting levels established by SARA 

Title III, Section 313. 

SARA 311/312 Hazards : Sudden Release of Pressure Hazard 

Acute Health Hazard 
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California Prop. 65 : This product does not contain any chemicals known to State of 

California to cause cancer, birth defects, or any other 

reproductive harm. 

WHMIS Classification : A: Compressed Gas 

This product has been classified according to the hazard criteria 

of the CPR and the MSDS contains all of the information 

required by the CPR.

SECTION 16. OTHER INFORMATION 

HMIS III NFPA

Health hazard : 1 2 

Flammability : 1 1 

Physical Hazard : 0 

Instability : 0 

Hazard rating and rating systems (e.g. HMIS® III, NFPA): This information is intended solely for the 

use of individuals trained in the particular system. 

Further information 

The information provided in this Safety Data Sheet is correct to the best of our knowledge, 

information and belief at the date of its publication. The information given is designed only as a 

guidance for safe handling, use, processing, storage, transportation, disposal and release and is not 

to be considered a warranty or quality specification. The information relates only to the specific 

material designated and may not be valid for such material used in combination with any other 

materials or in any process, unless specified in the text. Final determination of suitability of any 

material is the sole responsibility of the user. This information should not constitute a guarantee for 

any specific product properties. 

Changes since the last version are highlighted in the margin. This version replaces all previous 
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versions.

Previous Issue Date: 03/13/2013

Prepared by Honeywell Performance Materials and Technologies Product Stewardship Group