Federal Register / Vol. 86, No. 36 / Thursday, February 25, 2021 / Notices 11549 

clinical utility has been constrained, in 

part, by dose-limiting toxicity following 

systemic administration and the need 

for repeated dosing. The subject 

invention addresses these limitations 

through synthetic IL–15/21 sequences 

which incorporate flexible linker 

regions and cell membrane anchors. T 

cells engineered to express these 

constructs experience autocrine IL–15/ 

21 signaling leading to enhanced antitumor function in vivo. 

This Notice is made in accordance 

with 35 U.S.C. 209 and 37 CFR part 404. 

The prospective exclusive license will 

be royalty bearing, and the prospective 

exclusive license may be granted unless 

within fifteen (15) days from the date of 

this published Notice, the National 

Cancer Institute receives written 

evidence and argument establishing that 

the grant of the license would not be 

consistent with the requirements of 35 

U.S.C. 209 and 37 CFR part 404. 

In response to this Notice, the public 

may file comments or objections. 

Comments and objections, other than 

those in the form of a license 

application, will not be treated 

confidentially and may be made 

publicly available. 

License applications submitted in 

response to this Notice will be 

presumed to contain business 

confidential information and any release 

of information from these license 

applications will be made only as 

required and upon a request under the 

Freedom of Information Act, 5 U.S.C. 

552. 

Dated: February 12, 2021. 

Richard U. Rodriguez, 

Associate Director, Technology Transfer 

Center, National Cancer Institute. 

[FR Doc. 2021–03873 Filed 2–24–21; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Submission for OMB Review; 30-Day 

Comment Request; CareerTrac 

AGENCY: National Institutes of Health, 

HHS. 

ACTION: Notice. 

SUMMARY: In compliance with the 

Paperwork Reduction Act of 1995, the 

National Institutes of Health (NIH) has 

submitted to the Office of Management 

and Budget (OMB) a request for review 

and approval of the information 

collection listed below. 

DATES: Comments regarding this 

information collection are best assured 

of having their full effect if received 

within 30-days of the date of this 

publication. 

ADDRESSES: Written comments and 

recommendations for the proposed 

information collection should be sent 

within 30 days of publication of this 

notice to www.reginfo.gov/public/do/ 

PRAMain. Find this particular 

information collection by selecting 

‘‘Currently under 30-day Review—Open 

for Public Comments’’ or by using the 

search function. 

FOR FURTHER INFORMATION CONTACT: To 

request more information on the 

proposed project or to obtain a copy of 

the data collection plans and 

instruments, contact: Dr. Kristi 

Pettibone, Health Scientist 

Administrator, Program Analysis 

Branch, Division of Extramural Research 

and Training, NIEHS, NIH, 560 Davis 

Dr., Morrisville, NC 27560, or call nontoll-free number (984) 287–3303 or 

Email your request, including your 

address to: pettibonekg@niehs.nih.gov. 

SUPPLEMENTARY INFORMATION: This 

proposed information collection was 

previously published in the Federal 

Register on December 12, 2020, page 

79493–79494 (64 FR 15367) and 

allowed 60 days for public comment. No 

public comments were received. The 

purpose of this notice is to allow an 

additional 30 days for public comment. 

The Fogarty International Center (FIC), 

National Cancer Institute (NCI), 

National Institute of Diabetes and 

Digestive and Kidney Diseases (NIDDK), 

and National Institute of Environmental 

Health Sciences (NIEHS), may not 

conduct or sponsor, and the respondent 

is not required to respond to, an 

information collection that has been 

extended, revised, or implemented on or 

after October 1, 1995, unless it displays 

a currently valid OMB control number. 

In compliance with Section 

3507(a)(1)(D) of the Paperwork 

Reduction Act of 1995, the National 

Institutes of Health (NIH) has submitted 

to the Office of Management and Budget 

(OMB) a request for review and 

approval of the information collection 

listed below. 

Proposed Collection: CareerTrac0925–0568—expiration date April 30, 

2021, REVISION, Fogarty International 

Center (FIC), National Institute of 

Environmental Health Sciences 

(NIEHS), National Cancer Institute 

(NCI), National Institute of Diabetes and 

Digestive Kidney Diseases, (NIDDK), 

National Institutes of Health (NIH). 

Need and Use of Information 

Collection: The purpose of this data 

collection system is to track, evaluate 

and report short and long-term outputs, 

outcomes and impacts of trainees 

involved in health research training 

programs-specifically tracking this for at 

least ten years following training by 

having Principal Investigators enter data 

after trainees have completed the 

program. The data collection system 

provides a streamlined, web-based 

application permitting principal 

investigators to record career 

achievement progress by trainee on a 

voluntary basis. FIC, NCI, NIDDK, and 

NIEHS management will use this data to 

monitor, evaluate and adjust grants to 

ensure desired outcomes are achieved, 

comply with OMB Part requirements, 

respond to congressional inquiries, and 

as a guide to inform future strategic and 

management decisions regarding the 

grant program. 

OMB approval is requested for 3 

years. There are no costs to respondents 

other than their time. The total 

estimated annualized burden hours are 

12,705. 

ESTIMATED ANNUALIZED BURDEN HOURS

Type of respondent Number of 

respondents 

Number of 

responses per 

respondent 

Average 

burden per 

response 

(in hours) 

Total annual 

burden hour 

FIC Grantee ..................................................................................................... 90 20 40/60 1,200 

NIEHS Grantee ................................................................................................ 60 45 40/60 1,800 

NCI CRCHD Grantee ...................................................................................... 244 22 40/60 3,579 

NCI D43 Grantee ............................................................................................. 20 22 40/60 293 

Superfund Grantee .......................................................................................... 30 105 40/60 2,100 

11550 Federal Register / Vol. 86, No. 36 / Thursday, February 25, 2021 / Notices 

ESTIMATED ANNUALIZED BURDEN HOURS—Continued 

Type of respondent Number of 

respondents 

Number of 

responses per 

respondent 

Average 

burden per 

response 

(in hours) 

Total annual 

burden hour 

NIDDK Grantee ................................................................................................ 30 20 40/60 400 

Trainees ........................................................................................................... 5,000 1 40/60 3,333 

Total .......................................................................................................... 5,474 19,058 ........................ 12,705 

Jane M. Lambert, 

Project Clearance Liaison, National Institute 

of Environmental Health Sciences, National 

Institutes of Health. 

[FR Doc. 2021–03871 Filed 2–24–21; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Proposed Collection; 60 Day Comment 

Request; The Impact of Clinical 

Research Training and Medical 

Education at the Clinical Center on 

Physician Careers in Academia and 

Clinical Research (Clinical Center) 

AGENCY: National Institutes of Health, 

HHS. 

ACTION: Notice. 

SUMMARY: In compliance with the 

requirement of the Paperwork 

Reduction Act of 1995, for opportunity 

for public comment on proposed data 

collection projects, the Clinical Center, 

the National Institutes of Health (NIH) 

will publish periodic summaries of 

proposed projects to be submitted to the 

Office of Management and Budget 

(OMB) for review and approval. 

DATES: Comments regarding this 

information collection are best assured 

of having their full effect if received 

within 60 days of the date of this 

publication. 

FOR FURTHER INFORMATION CONTACT: To 

obtain a copy of the data collection 

plans and instruments, contact: Robert 

M. Lembo, MD, Office of Clinical 

Research Training and Medical 

Education, NIH Clinical Center, 

National Institutes of Health, 10 Center 

Drive, Room 1N252C, Bethesda, MD 

20892–1158, or call non-toll-free 

number (301) 496–2636, or Email your 

request, including your address to: 

robert.lembo@nih.gov. Formal requests 

for additional plans and instruments 

must be requested in writing. 

SUPPLEMENTARY INFORMATION: Section 

3506(c)(2)(A) of the Paperwork 

Reduction Act of 1995 requires: Written 

comments and/or suggestions from the 

public and affected agencies are invited 

to address one or more of the following 

points: (1) Whether the proposed 

collection of information is necessary 

for the proper performance of the 

function of the agency, including 

whether the information will have 

practical utility; (2) The accuracy of the 

agency’s estimate of the burden of the 

proposed collection of information, 

including the validity of the 

methodology and assumptions used; (3) 

Ways to enhance the quality, utility, and 

clarity of the information to be 

collected; and (4) Ways to minimizes 

the burden of the collection of 

information on those who are to 

respond, including the use of 

appropriate automated, electronic, 

mechanical, or other technological 

collection techniques or other forms of 

information technology. 

Proposed Collection Title: The Impact 

of Clinical Research Training and 

Medical Education at the Clinical Center 

on Physician Careers in Academia and 

Clinical Research, OMB #0925–0602 

Expiration Date: 11/30/2022, REVISION, 

Clinical Center (CC), National Institutes 

of Health (NIH). 

Need and Use of Information 

Collection: The information collected 

will allow continued assessment of the 

value of the training provided by the 

Office of Clinical Research Training and 

Medical Education (OCRTME) at the 

NIH Clinical Center and the extent to 

which this training promotes (a) patient 

safety; (b) research productivity and 

independence; and (c) future career 

development within clinical, 

translational, and academic research 

settings. The information received from 

respondents is presented to, evaluated 

by, and incorporated into the ongoing 

operational improvement efforts of the 

Director of the Office of Clinical 

Research Training and Education, and 

the Chief Executive Officer of the NIH 

Clinical Center. This information will 

enable the ongoing operational 

improvement efforts of the OCRTME 

and its commitment to providing 

clinical research training and medical 

education of the highest quality to each 

trainee. 

OMB approval is requested for 3 

years. There are no costs to respondents 

other than their time. The total 

estimated annualized burden hours 478. 

ESTIMATED ANNUALIZED BURDEN HOURS

Form name Number of 

respondents 

Number of 

responses per 

respondent 

Average 

burden 

per response 

(in hours) 

Total annual 

burden hours 

requested 

CRTP/MRSP Alumni Survey ........................................................................... 704 1 20/60 235 

Summer Internship Program Alumni Survey ................................................... 280 1 20/60 93 

Graduate Medical Education Graduate Survey ............................................... 350 1 20/60 117 

Clinical Electives Program 1 Year Alumni Surveys ......................................... 100 1 20/60 33 

Total .......................................................................................................... 1,434 1,434 ........................ 478