Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

Office of Chemical Safety and Pollution Prevention 

 

MEMORANDUM

Date: July 21, 2010 

SUBJECT: Propiconazole: Acute and Chronic Aggregate Dietary (Food and 

Drinking Water) Exposure and Risk Assessments for the Section 18 

Registration on Avocado in Florida. 

PC Code: 122101 DP Barcode: D380158 

Decision No.: 436555 Registration No.: 10FL02 

Petition No.: NA Regulatory Action: Section 18 

Risk Assessment Type: Dietary assessment Case No.: 3125. 

TXR No.: N/A CAS No.: 60207-90-1 

MRID No.: N/A 40 CFR: § 180.434 

FROM: Thurston G. Morton, Chemist 

Risk Assessment Branch IV 

Health Effects Division (7509P) 

THROUGH: Amelia Acierto, Chemist 

Dennis McNeilly, Chemist 

Dietary Exposure Science Advisory Council (DESAC) 

Health Effects Division (7509P) 

And 

Susan Hummel, Senior Scientist 

Risk Assessment Branch IV 

Health Effects Division (7509P) 

TO: Bonnie Cropp-Kohlligian, Environmental Scientist/Risk Assessor 

Risk Assessment Branch IV 

 Health Effects Division (7509P) 

And 

Andrea Conrath/Barbara Madden 

RIMUERB 

Registration Division (7505P) 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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Executive Summary

Acute and chronic aggregate dietary (food and drinking water) exposure and risk 

assessments were conducted using the Dietary Exposure Evaluation Model DEEMFCIDTM, Version 2.03 which use food consumption data from the U.S. Department of 

Agriculture’s Continuing Surveys of Food Intakes by Individuals (CSFII) from 1994-

1996 and 1998. The analyses were performed to support the Section 18 registrations on 

avocado in Florida. 

Attached are acute and chronic dietary risk assessments for this new use. This dietary 

assessment is for residues of propiconazole and its metabolites convertible to 2,4-

dichlorobenzoic acid (2,4-DCBA), expressed as propiconazole equivalents. The common 

metabolites- triazole, triazolylalanine (TA), triazolylacetic acid (TAA), and 

triazolylpyruvic acid are also residues of concern. Since these are common metabolites 

from several triazole pesticides, the risk assessment for triazoles will be assessed 

separately. 

 

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization

An acute dietary analysis for propiconazole residues of concern was conducted using 

tolerance levels and 100 %CT for all existing and proposed uses. The acute PAD is 0.3 

mg/kg/day for all population subgroups (includes females 13-49 years). The results of 

the analysis indicate that acute risk from the dietary exposure (food and water) to 

propiconazole from the requested uses did not exceed HED’s level of concern for the 

U.S. population or any population subgroup. At the 95th percentile, the exposure to the 

U.S. population is 7 % of the aPAD; the highest exposed subgroup (Children 1-2 yrs old) 

is 17% of the aPAD. 

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization

A chronic dietary analysis for propiconazole residues of concern was conducted using 

tolerance levels and 100 %CT for all existing and proposed uses. The cPAD is 0.1 

mg/kg/day. Results of the analysis indicate that chronic risk from the dietary exposure 

(food and water) to propiconazole from the requested use did not exceed HED’s level of 

concern for the U.S. population or any population subgroup. The exposure to the U.S. 

population is 7 % of the cPAD, and the most highly exposed subgroup, Children 1-2 

years old, is 18 % of the cPAD. 

Cancer Dietary (Food and Drinking Water) Exposure Results and Characterization

The HED Carcinogenicity Peer Review Committee (CPRC) classified propiconazole as 

Group C - possible human carcinogen and recommended that for the purpose of risk 

characterization the reference Dose (RfD) approach should be used and would be 

protective. 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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I. Introduction

Propiconazole is a triazole-type fungicide that provides broad spectrum disease control 

through inhibition of sterol biosynthesis in fungi. It is registered to Syngenta Crop 

Protection for the control of fungal diseases on a variety of crops. This dietary exposure 

assessment is for a proposed Section 18 on Florida avocado. 

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For 

acute and chronic assessments, the risk is expressed as a percentage of a maximum 

acceptable dose (i.e., the dose which HED has concluded will result in no unreasonable 

adverse health effects). This dose is referred to as the population adjusted dose (PAD). 

The PAD is equivalent to point of departure (POD, NOAEL, LOAEL, e.g.) divided by 

the required uncertainty or safety factors. 

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary 

risk exceeds 100% of the PAD. HED is generally concerned when estimated cancer risk 

exceeds one in one million. References which discuss the acute and chronic risk 

assessments in more detail are available on the EPA/pesticides web site: “Available 

Information on Assessing Exposure from Pesticides, A User’s Guide,” 21-JUN-2000, 

web link: http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf ; or see 

SOP 99.6 (20-AUG-1999). 

The most recent dietary risk assessment for propiconazole was conducted by Yan 

Donovan, (DP 355821, 09/30/08). 

II. Residue Information

Residue Data used for Acute and Chronic Assessments:

These acute and chronic assessments were based on the assumption of tolerance-level 

residues for all commodities with existing and proposed tolerances and 100% crop treated 

(%CT) for all commodities. The existing tolerances are listed in 40 CFR §180.434. The 

proposed new tolerance level used in the DEEM are presented in Table 1. DEEM default 

processing factors from DEEM (Version 7.81) were used for all processed commodities 

that do not have individual tolerance. 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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Propiconazole existing tolerances: 

Sec. 180.434 Propiconazole; tolerances for residues. 

 (a) General. 

----------------------------------------------------------------------- 

 Parts per 

 Commodity million 

----------------------------------------------------------------------- 

Almond, hulls.............................................. 7.0 

Banana...................................................... 0.2 

Barley, bran................................................ 0.6 

Barley, grain............................................... 0.3 

Barley, hay................................................. 1.4 

Barley, straw............................................... 10 

Beet, sugar, dried pulp..................................... 1.0 

Beet, sugar, molasses....................................... 1.5 

Beet, sugar, roots.......................................... 0.3 

Beet, sugar, tops........................................... 10 

Berry, group 13............................................. 1.0 

Carrot, roots............................................... 0.25 

Cattle, fat................................................. 0.05 

Cattle, kidney.............................................. 2.0 

Cattle, liver............................................... 2.0 

Cattle, meat................................................ 0.05 

Cattle, meat byproducts, except liver and kidney............ 0.05 

Corn, field, forage......................................... 12 

Corn, field, grain.......................................... 0.2 

Corn, field, stover......................................... 30 

Corn, pop, grain............................................ 0.2 

Corn, pop, stover........................................... 30 

Corn, sweet, forage......................................... 6.0 

Corn, sweet, kernel plus cob with husks removed............. 0.1 

Corn, sweet, stover......................................... 30 

Fruit, stone, group 12...................................... 1.0 

Goat, fat................................................... 0.05 

Goat, kidney................................................ 2.0 

Goat, liver................................................. 2.0 

Goat, meat.................................................. 0.05 

Goat, meat byproducts, except liver and kidney.............. 0.05 

Grain, aspirated fractions.................................. 30 

Grass, forage............................................... 0.5 

Grass, hay.................................................. 0.5 

Grass, straw................................................ 40 

Hog, kidney................................................. 0.2 

Hog, liver.................................................. 0.2 

Horse, fat.................................................. 0.05 

Horse, kidney............................................... 2.0 

Horse, liver................................................ 2.0 

Horse, meat................................................. 0.05 

Horse, meat byproducts, except liver and kidney............. 0.05 

Leaf petioles, subgroup 4B.................................. 5.0 

Milk........................................................ 0.05 

Mushroom.................................................... 0.1 

Nut, tree, group 14......................................... 0.1 

Oat, forage................................................. 1.7 

Oat, grain.................................................. 0.3 

Oat, hay.................................................... 1.4 

Oat, straw.................................................. 10 

Onion, bulb................................................. 0.2 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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Onion, green................................................ 9.0 

Peanut...................................................... 0.2 

Peanut, hay................................................. 20 

Peppermint, tops............................................ 3.5 

Pineapple................................................... 0.1 

Pistachio................................................... 0.1 

Rice, bran.................................................. 15 

Rice, grain................................................. 7.0 

Rice, hulls................................................. 20 

Rice, straw................................................. 18 

Rye, bran................................................... 0.6 

Rye, forage................................................. 1.7 

Rye, grain.................................................. 0.3 

Rye, straw.................................................. 10 

Sheep, fat.................................................. 0.05 

Sheep, kidney............................................... 2.0 

Sheep, liver................................................ 2.0 

Sheep, meat................................................. 0.05 

Sheep, meat byproducts, except liver and kidney............. 0.05 

Sorghum, grain, forage...................................... 12 

Sorghum, grain, grain....................................... 3.5 

Sorghum, grain, stover...................................... 15 

Soybean, forage............................................. 11 

Soybean, hay................................................ 30 

Soybean, seed............................................... 2.0 

Spearmint, tops............................................. 3.5 

Strawberry.................................................. 1.3 

Wheat, bran................................................. 0.6 

Wheat, forage............................................... 1.7 

Wheat, grain................................................ 0.3 

Wheat, hay.................................................. 1.4 

Wheat, straw................................................ 10 

----------------------------------------------------------------------- 

 (b) Section 18 emergency exemptions. 

----------------------------------------------------------------------- 

 Expiration/ 

 Commodity Parts per revocation 

 million date 

----------------------------------------------------------------------- 

Nectarine....................................... 2.0 12/31/2010 

Peach........................................... 2.0 12/31/2010 

----------------------------------------------------------------------- 

 (c) Tolerances with regional registrations 

----------------------------------------------------------------------- 

 

 Parts per 

 Commodity million 

----------------------------------------------------------------------- 

 Cranberry.................................................. 1.0 

Rice, wild, grain........................................... 0.5 

----------------------------------------------------------------------- 

 (d) Indirect or inadvertent residues. 

----------------------------------------------------------------------- 

 Parts per 

 Commodity million 

----------------------------------------------------------------------- 

 Alfalfa, forage............................................ 0.1 

Alfalfa, hay................................................ 0.1 

----------------------------------------------------------------------- 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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[71 FR 55306, Sept. 22, 2006, as amended at 72 FR 20439, Apr. 25, 2007] 

HED’s recommended tolerance associated with the Section 18 use: 

Table 1. Tolerance Summary for Propiconazole 

Commodity Proposed 

Tolerance (ppm) 

Recommended 

Tolerance (ppm) 

Comments; Correct 

Commodity Definition

Avocado 10.0 

III. Drinking Water Data 

The drinking water residues used in the dietary risk assessment were provided by the 

Environmental Fate and Effects Division (EFED) in the following memorandum: 

“Drinking Water Assessment for Propiconazole Uses on Florida Avocado – Section 18 

Emergency Exemption” (Jim Lin, 07/15/10, D379850) and incorporated directly into this 

dietary assessment. Water residues were incorporated in the DEEM-FCID into the food 

categories “water, direct, all sources” and “water, indirect, all sources.” 

These results are based on EDWCs for Turf (DP 325821, 328690, 07/07/2006). The 

proposed new use does not result in higher EDWCs than those estimated for turf uses. 

The estimated surface water drinking water concentrations for propiconazole are: 

55.78 ug /L for the 1 in 10 year annual peak concentration (acute) 

21.61 ug /L for the 1 in 10 year annual mean concentration (non-cancer chronic) and 

13.24 ug /L for the 30 year annual mean concentration (cancer chronic). 

The SCI-GROW estimated ground water drinking water concentrations for 

propiconazole are not expected to exceed 0.64 μg/L

The highest estimates from surface water (acute, 55.8 ppb and chronic, 21.6 ppb) are 

directly entered into the exposure model to assess the contributions from drinking water. 

The model and its description are available at the EPA internet site: 

http://www.epa.gov/oppefed1/models/water/. 

IV. DEEM-FCIDTM Program and Consumption Information

Propiconazole acute and chronic dietary exposure assessments were conducted using the 

Dietary Exposure Evaluation Model software with the Food Commodity Intake Database 

DEEM-FCIDTM, Version 2.03 which incorporates consumption data from USDA’s 

Continuing Surveys of Food Intakes by Individuals (CSFII), 1994-1996 and 1998. The 

1994-96, 98 data are based on the reported consumption of more than 20,000 individuals 

over two non-consecutive survey days. Foods “as consumed” (e.g., apple pie) are linked 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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to EPA-defined food commodities (e.g. apples, peeled fruit - cooked; fresh or N/S; baked; 

or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation 

files developed jointly by USDA/ARS and EPA. For chronic exposure assessment, 

consumption data are averaged for the entire U.S. population and within population 

subgroups, but for acute exposure assessment are retained as individual consumption 

events. Based on analysis of the 1994-96, 98 CSFII consumption data, which took into 

account dietary patterns and survey respondents, HED concluded that it is most 

appropriate to report risk for the following population subgroups: the general U.S. 

population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-

19, adults 20-49, females 13-49, and adults 50+ years old. 

For chronic dietary exposure assessment, an estimate of the residue level in each food or 

food-form (e.g., orange or orange juice) on the food commodity residue list is multiplied 

by the average daily consumption estimate for that food/food form to produce a residue 

intake estimate. The resulting residue intake estimate for each food/food form is summed 

with the residue intake estimates for all other food/food forms on the commodity residue 

list to arrive at the total average estimated exposure. Exposure is expressed in mg/kg 

body weight/day and as a percent of the cPAD. This procedure is performed for each 

population subgroup. 

For acute exposure assessments, individual one-day food consumption data are used on 

an individual-by-individual basis. The reported consumption amounts of each food item 

can be multiplied by a residue point estimate and summed to obtain a total daily pesticide 

exposure for a deterministic exposure assessment, or “matched” in multiple random 

pairings with residue values and then summed in a probabilistic assessment. The 

resulting distribution of exposures is expressed as a percentage of the aPAD on both a 

user (i.e., only those who reported eating relevant commodities/food forms) and a percapita (i.e., those who reported eating the relevant commodities as well as those who did 

not) basis. 

V. Toxicological Information 

HED’s Hazard Identification Assessment Review Committee (HIARC) concluded that 

the toxicology database for propiconazole is complete for FQPA assessment. Endpoints 

and dose response have been selected for acute and chronic dietary exposures. 

The HIARC also concluded that the database was adequate to characterize any potential 

for prenatal or postnatal risk for infants and children. There is low concern for preand/or postnatal toxicity resulting from exposure to propiconazole, and no residual 

uncertainties were identified. The Special FQPA factor is thus 1X. The HIARC had 

previously determined that an acute neurotoxicity (ACN) study was required based on 

neurotoxic signs in pregnant rats administered high propiconazole doses (360 mg/kg/day) 

during gestation. HIARC had determined that for acute (single dose) and short-term 

exposure scenarios a 3X database uncertainty factor (UFDB) was adequate to account for 

the lack of the ACN. In September 2005 the ACN was submitted to the Agency and 

reviewed. The study confirms that neurotoxic signs are observed at high doses, but there 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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was no neuropathology and there were no effects on neurobehavioral parameters. 

Accordingly, the propiconazole risk assessment team determined that a developmental 

neurotoxicity study was not necessary and the database uncertainty factor for acute and 

short-term scenarios was removed. 

The HED Carcinogenicity Peer Review Committee (CPRC) classified propiconazole as 

Group C - possible human carcinogen and recommended that for the purpose of risk 

characterization the reference Dose (RfD) approach should be used and would be 

protective. 

Table 2 Summary of Toxicological Doses and Endpoints for Propiconazole for Use in 

Dietary Exposure Risk Assessments 

Exposure/ 

Scenario 

Point of 

Departure 

Uncertainty/FQPA 

Safety Factors 

RfD, PAD, Level 

of Concern 

Study and Toxicological 

Effects 

Acute 

Dietary 

(General 

Population, 

including 

Infants and 

Children) 

NOAEL= 

30 

mg/kg/day 

UFA= 10x 

UFH= 10x 

FQPA SF= 1x 

Acute RfD = 0.3 

mg/kg/day 

aPAD =0.3 

mg/kg/day 

Acute neurotoxicity study 

LOAEL = 100 mg/kg/day based 

on clinical signs of toxicity 

(piloerection in one male, 

diarrhea in one female, tip toe 

gait in 3 females). 

Acute 

Dietary 

(Females 13-

49 years of 

age) 

NOAEL = 

30 

mg/kg/day 

UFA= 10x 

UFH= 10x 

FQPA SF= 1x 

Acute RfD = 0.3 

mg/kg/day 

aPAD =0.3 

mg/kg/day 

Developmental Toxicity Study - 

Rats. 

LOAEL = 90 mg/kg/day based 

on increased incidence of 

rudimentary ribs, un-ossified 

sternebrae, as well as increased 

incidence of shortened and 

absent renal papillae and 

increased cleft palate. 

Chronic 

Dietary (All 

Populations) 

NOAEL= 

10 

mg/kg/day 

UFA= 10x 

UFH= 10x 

FQPA SF= 1x 

Chronic RfD = 0.1 

mg/kg/day 

cPAD = 

0.1mg/kg/day 

24-month oncogenicity study 

on CD-1 mice. 

LOAEL = 50 mg/kg/day based 

on non-neoplastic liver effects 

(increased liver weight in males 

and increase in liver lesions: 

masses/raised areas/ 

swellings/nodular areas 

mainly). 

Cancer (oral, dermal, 

inhalation) 

Classification: Group C, possible human carcinogen, RfD approach for risk 

characterization. 

Point of Departure (POD) = A data point or an estimated point that is derived from observed dose-response 

data and used to mark the beginning of extrapolation to determine risk associated with lower 

environmentally relevant human exposures. NOAEL = no observed adverse effect level. LOAEL = lowest 

observed adverse effect level. UF = uncertainty factor. UFA = extrapolation from animal to human 

(intraspecies). UFH = potential variation in sensitivity among members of the human population 

(interspecies). UFDB = to account for the absence of key data (i.e., lack of a critical study). FQPA SF = 

FQPA Safety Factor. PAD = population adjusted dose (a = acute, c = chronic). RfD = reference dose. 

N/A = not applicable. 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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VI. Results/Discussion 

As stated above, for acute and chronic assessments, HED is concerned when dietary risk 

exceeds 100% of the PAD. The DEEM-FCIDTM analyses estimate the dietary exposure 

of the U.S. population and various population subgroups. The results reported in Table(s) 

are for the general U.S. Population, all infants (<1 year old), children 1-2, children 3-5, 

children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50+ years. Cancer 

risk is determined for the general U.S. population only. 

At the 95th percentile, the acute dietary exposure (food and water) to general US 

population is 7 % of the aPAD, and the most highly exposed subgroup, Children 1-2 yrs 

old, is 17 % of the aPAD. The chronic dietary exposure to general US population is 7 % 

of the cPAD, and the most highly exposed subgroup, Children 1-2 yrs old, is 18 % of the 

cPAD. All the dietary risk estimates are below 100% of the PADs. 

These analyses are highly conservative dietary exposure assessments. Further refinement 

to the analyses could be made through the use of anticipated residues, incorporation of 

percentages of crops treated with propiconazole, and/or monitoring data that better reflect 

residues at the time of consumption. Since risk estimates are well below HED’s level of 

concern, a more highly refined analysis is not needed at this time. 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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Results of Acute Dietary (Food and Drinking Water) Exposure Analysis

Table 3. Results of Acute Dietary Exposure Analysis for FOOD and Water 

Population Subgroup 

aPAD 

(mg/kg/day) 

95th Percentile 99th Percentile 99.9th Percentile 

Exposure 

(mg/kg/day) % aPAD 

Exposure 

(mg/kg/day) % aPAD 

Exposure 

(mg/kg/day) % aPAD 

General U.S. Population 0.3 0.022027 7 0.043031 14 0.103143 34 

All Infants (< 1 year old) 0.3 0.048208 16 0.092614 31 0.193255 64 

Children 1-2 years old 0.3 0.051511 17 0.107628 36 0.227469 76 

Children 3-5 years old 0.3 0.039625 13 0.078240 26 0.165767 55 

Children 6-12 years old 0.3 0.027151 9 0.048646 16 0.091310 30 

Youth 13-19 years old 0.3 0.018019 6 0.037944 13 0.063133 21 

Adults 20-49 years old 0.3 0.017908 6 0.033322 11 0.089665 30 

Adults 50+ years old 0.3 0.013500 5 0.025841 9 0.050482 17 

Females 13-49 years old 0.3 0.016757 6 0.030951 10 0.093153 31 

Results of Chronic Dietary (Food and Drinking Water) Exposure Analysis

Table 4. Results of Chronic Dietary Exposure Analysis for FOOD and Water

Population Subgroup 

cPAD 

(mg/kg/day) 

Exposure 

(mg/kg/day) % cPAD 

General U.S. Population 0.1 0.006790 7 

All Infants (< 1 year old) 0.1 0.015833 16 

Children 1-2 years old 0.1 0.018203 18 

Children 3-5 years old 0.1 0.014752 15 

Children 6-12 years old 0.1 0.009621 10 

Youth 13-19 years old 0.1 0.005886 6 

Adults 20-49 years old 0.1 0.005682 6 

Adults 50+ years old 0.1 0.004553 5 

Females 13-49 years old 0.1 0.005366 5 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

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VII. Characterization of Inputs/Outputs

The acute and chronic analysis assumed tolerance-level residues, 100% CT, and 

empirical or DEEMTM default processing factors. Therefore, these analyses are 

considered conservative. Since risk estimates are well below HED’s level of concern 

they do not warrant the need for further refinement at this time. 

VIII. Conclusions

These unrefined analyses demonstrate that the requested uses for propiconazole will not 

result in dietary risk estimates that exceed HED’s level of concern for any of the 

regulated population subgroups, including those comprised of infants and children. A 

summary of the dietary exposure analyses is given in Table 5. 

Table 5. Summary of Dietary Exposure and Risk for Propiconazole FOOD PLUS WATER.

Population Subgroup* 

Acute Dietary 

(95th Percentile) Chronic Dietary Cancer 

Dietary 

Exposure 

(mg/kg/day) % aPAD 

Dietary 

Exposure 

(mg/kg/day) % cPAD 

Dietary 

Exposure 

(mg/kg/day) Risk 

General U.S. Population 0.022027 7 0.006790 7 

N/A 

All Infants (< 1 year old) 0.048208 16 0.015833 16 

Children 1-2 years old 0.051511 17 0.018203 18 

Children 3-5 years old 0.039625 13 0.014752 15 

Children 6-12 years old 0.027151 9 0.009621 10 

Youth 13-19 years old 0.018019 6 0.005886 6 

Adults 20-49 years old 0.017908 6 0.005682 6 

Adults 50+ years old 0.013500 5 0.004553 5 

Females 13-49 years old 0.016757 6 0.005366 5 
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IX. List of Attachments

Attachment 1. Acute Food plus Water Residue Input file. 

Attachment 2. Acute Results file. 

Attachment 3. Chronic Food plus Water Residue Input file. 

Attachment 4. Chronic Results file. 

cc with all attachments: T. Morton (RABIV) 

RDI: P. Amelia Acierto and Dennis McNeilly - DESAC (15-July-2010); Susan Hummel (7/21/2010) 

DP#: 380158 

PC Code: 122101 

T. Morton:S10922:PY1:(703)305-6691 

 
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Attachment 1. Acute Food plus Water Residue Input file. 

Filename: C:\Documents and Settings\tmorton\My Documents\MyFiles\DEEM Files\122101 

Propiconazole\Section 18 Avocado\122101 Acute 7-2010 Sec 18 Avocado.R98 

Chemical: Propiconazole 

RfD(Chronic): .1 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day 

RfD(Acute): .3 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day 

Date created/last modified: 07-14-2010/14:00:37/8 Program ver. 2.03 

-------------------------------------------------------------------------------- 

 EPA Crop Def Res Adj.Factors Comment 

 Code Grp Commodity Name (ppm) #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ ------- 

95000200 O Avocado 10.000000 1.000 1.000 

95000230 O Banana 0.200000 1.000 1.000 

95000231 O Banana-babyfood 0.200000 1.000 1.000 

95000240 O Banana, dried 0.200000 3.900 1.000 

95000241 O Banana, dried-babyfood 0.200000 3.900 1.000 

95001300 O Cranberry 1.000000 1.000 1.000 

95001301 O Cranberry-babyfood 1.000000 1.000 1.000 

95001310 O Cranberry, dried 1.000000 1.000 1.000 

95001320 O Cranberry, juice 1.000000 1.100 1.000 

95001321 O Cranberry, juice-babyfood 1.000000 1.100 1.000 

95002280 O Mushroom 0.100000 1.000 1.000 

95002630 O Peanut 0.200000 1.000 1.000 

95002640 O Peanut, butter 0.200000 1.890 1.000 

95002650 O Peanut, oil 0.200000 1.000 1.000 

95002750 O Peppermint 3.500000 1.000 1.000 

95002760 O Peppermint, oil 3.500000 1.000 1.000 

95002790 O Pineapple 4.500000 1.000 1.000 

95002791 O Pineapple-babyfood 4.500000 1.000 1.000 

95002800 O Pineapple, dried 4.500000 5.000 1.000 

95002810 O Pineapple, juice 4.500000 1.700 1.000 

95002811 O Pineapple, juice-babyfood 4.500000 1.700 1.000 

95002830 O Plantain 0.200000 1.000 1.000 

95002840 O Plantain, dried 0.200000 3.900 1.000 

95003520 O Spearmint 3.500000 1.000 1.000 

95003530 O Spearmint, oil 3.500000 1.000 1.000 

95003590 O Strawberry 1.300000 1.000 1.000 

95003591 O Strawberry-babyfood 1.300000 1.000 1.000 

95003600 O Strawberry, juice 1.300000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 1.300000 1.000 1.000 

86010000 O Water, direct, all sources 0.055780 1.000 1.000 

86020000 O Water, indirect, all sources 0.055780 1.000 1.000 

21000440 M Beef, meat 0.050000 1.000 1.000 

21000441 M Beef, meat-babyfood 0.050000 1.000 1.000 

21000450 M Beef, meat, dried 0.050000 1.920 1.000 

21000460 M Beef, meat byproducts 0.050000 1.000 1.000 

21000461 M Beef, meat byproducts-babyfood 0.050000 1.000 1.000 

21000470 M Beef, fat 0.050000 1.000 1.000 

21000471 M Beef,fat-babyfood 0.050000 1.000 1.000 

21000480 M Beef, kidney 2.000000 1.000 1.000 

21000490 M Beef, liver 2.000000 1.000 1.000 

21000491 M Beef, liver-babyfood 2.000000 1.000 1.000 

23001690 M Goat, meat 0.050000 1.000 1.000 

23001700 M Goat, meat byproducts 0.050000 1.000 1.000 

23001710 M Goat, fat 0.050000 1.000 1.000 

23001720 M Goat, kidney 2.000000 1.000 1.000 

23001730 M Goat, liver 2.000000 1.000 1.000 

24001890 M Horse, meat 0.050000 1.000 1.000 

25002940 M Pork, kidney 0.200000 1.000 1.000 

25002950 M Pork, liver 0.200000 1.000 1.000 

26003390 M Sheep, meat 0.050000 1.000 1.000 

26003391 M Sheep, meat-babyfood 0.050000 1.000 1.000 

26003400 M Sheep, meat byproducts 0.050000 1.000 1.000 

26003410 M Sheep, fat 0.050000 1.000 1.000 

26003411 M Sheep, fat-babyfood 0.050000 1.000 1.000 

26003420 M Sheep, kidney 2.000000 1.000 1.000 

26003430 M Sheep, liver 2.000000 1.000 1.000 

27002220 D Milk, fat 0.050000 1.000 1.000 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

______________________________________________________________________________________

Page 14 of 20 

27002221 D Milk, fat - baby food/infant for 0.050000 1.000 1.000 

27012230 D Milk, nonfat solids 0.050000 1.000 1.000 

27012231 D Milk, nonfat solids-baby food/in 0.050000 1.000 1.000 

27022240 D Milk, water 0.050000 1.000 1.000 

27022241 D Milk, water-babyfood/infant form 0.050000 1.000 1.000 

27032251 D Milk, sugar (lactose)-baby food/ 0.050000 1.000 1.000 

01010500 1AB Beet, garden, roots 0.300000 1.000 1.000 

01010501 1AB Beet, garden, roots-babyfood 0.300000 1.000 1.000 

01010520 1A Beet, sugar 0.300000 1.000 1.000 

01010521 1A Beet, sugar-babyfood 0.300000 1.000 1.000 

01010530 1A Beet, sugar, molasses 1.500000 1.000 1.000 

01010531 1A Beet, sugar, molasses-babyfood 1.500000 1.000 1.000 

01010780 1AB Carrot 0.250000 1.000 1.000 

01010781 1AB Carrot-babyfood 0.250000 1.000 1.000 

01010790 1AB Carrot, juice 0.250000 1.000 1.000 

02000510 2 Beet, garden, tops 5.500000 1.000 1.000 

03002370 3 Onion, dry bulb 0.200000 1.000 1.000 

03002371 3 Onion, dry bulb-babyfood 0.200000 1.000 1.000 

03002380 3 Onion, dry bulb, dried 0.200000 9.000 1.000 

03002381 3 Onion, dry bulb, dried-babyfood 0.200000 9.000 1.000 

03002390 3 Onion, green 9.000000 1.000 1.000 

04020760 4B Cardoon 5.000000 1.000 1.000 

04020850 4B Celery 5.000000 1.000 1.000 

04020851 4B Celery-babyfood 5.000000 1.000 1.000 

04020860 4B Celery, juice 5.000000 1.000 1.000 

04020870 4B Celtuce 5.000000 1.000 1.000 

04021520 4B Fennel, Florence 5.000000 1.000 1.000 

04012480 4A Parsley, leaves 13.000000 1.000 1.000 

04023220 4B Rhubarb 5.000000 1.000 1.000 

04023670 4B Swiss chard 5.000000 1.000 1.000 

06003470 6 Soybean, seed 2.000000 1.000 1.000 

06003480 6 Soybean, flour 2.000000 1.000 1.000 

06003481 6 Soybean, flour-babyfood 2.000000 1.000 1.000 

06003490 6 Soybean, soy milk 2.000000 1.000 1.000 

06003491 6 Soybean, soy milk-babyfood or in 2.000000 1.000 1.000 

06003500 6 Soybean, oil 2.000000 1.000 1.000 

06003501 6 Soybean, oil-babyfood 2.000000 1.000 1.000 

12000120 12 Apricot 1.000000 1.000 1.000 

12000121 12 Apricot-babyfood 1.000000 1.000 1.000 

12000130 12 Apricot, dried 1.000000 6.000 1.000 

12000140 12 Apricot, juice 1.000000 1.000 1.000 

12000141 12 Apricot, juice-babyfood 1.000000 1.000 1.000 

12000900 12 Cherry 1.000000 1.000 1.000 

12000901 12 Cherry-babyfood 1.000000 1.000 1.000 

12000910 12 Cherry, juice 1.000000 1.500 1.000 

12000911 12 Cherry, juice-babyfood 1.000000 1.500 1.000 

12002300 12 Nectarine 2.000000 1.000 1.000 

12002600 12 Peach 2.000000 1.000 1.000 

12002601 12 Peach-babyfood 2.000000 1.000 1.000 

12002610 12 Peach, dried 2.000000 7.000 1.000 

12002611 12 Peach, dried-babyfood 2.000000 7.000 1.000 

12002620 12 Peach, juice 2.000000 1.000 1.000 

12002621 12 Peach, juice-babyfood 2.000000 1.000 1.000 

12002850 12 Plum 1.000000 1.000 1.000 

12002851 12 Plum-babyfood 1.000000 1.000 1.000 

12002860 12 Plum, prune, fresh 1.000000 1.000 1.000 

12002861 12 Plum, prune, fresh-babyfood 1.000000 1.000 1.000 

12002870 12 Plum, prune, dried 1.000000 5.000 1.000 

12002871 12 Plum, prune, dried-babyfood 1.000000 5.000 1.000 

12002880 12 Plum, prune, juice 1.000000 1.400 1.000 

12002881 12 Plum, prune, juice-babyfood 1.000000 1.400 1.000 

13010550 13A Blackberry 1.000000 1.000 1.000 

13010560 13A Blackberry, juice 1.000000 1.000 1.000 

13010561 13A Blackberry, juice-babyfood 1.000000 1.000 1.000 

13020570 13B Blueberry 1.000000 1.000 1.000 

13020571 13B Blueberry-babyfood 1.000000 1.000 1.000 

13010580 13A Boysenberry 1.000000 1.000 1.000 

13021360 13B Currant 1.000000 1.000 1.000 

13021370 13B Currant, dried 1.000000 1.000 1.000 

13011420 13A Dewberry 1.000000 1.000 1.000 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

______________________________________________________________________________________

Page 15 of 20 

13021490 13B Elderberry 1.000000 1.000 1.000 

13021740 13B Gooseberry 1.000000 1.000 1.000 

13021910 13B Huckleberry 1.000000 1.000 1.000 

13012080 13A Loganberry 1.000000 1.000 1.000 

13013200 13A Raspberry 1.000000 1.000 1.000 

13013201 13A Raspberry-babyfood 1.000000 1.000 1.000 

13013210 13A Raspberry, juice 1.000000 1.000 1.000 

13013211 13A Raspberry, juice-babyfood 1.000000 1.000 1.000 

14000030 14 Almond 0.100000 1.000 1.000 

14000031 14 Almond-babyfood 0.100000 1.000 1.000 

14000040 14 Almond, oil 0.100000 1.000 1.000 

14000041 14 Almond, oil-babyfood 0.100000 1.000 1.000 

14000590 14 Brazil nut 0.100000 1.000 1.000 

14000680 14 Butternut 0.100000 1.000 1.000 

14000810 14 Cashew 0.100000 1.000 1.000 

14000920 14 Chestnut 0.100000 1.000 1.000 

14001550 14 Filbert 0.100000 1.000 1.000 

14001560 14 Filbert, oil 0.100000 1.000 1.000 

14001850 14 Hickory nut 0.100000 1.000 1.000 

14002130 14 Macadamia nut 0.100000 1.000 1.000 

14002690 14 Pecan 0.100000 1.000 1.000 

14002820 14 Pistachio 0.100000 1.000 1.000 

14003910 14 Walnut 0.100000 1.000 1.000 

15000250 15 Barley, pearled barley 0.300000 1.000 1.000 

15000251 15 Barley, pearled barley-babyfood 0.300000 1.000 1.000 

15000260 15 Barley, flour 0.300000 1.000 1.000 

15000261 15 Barley, flour-babyfood 0.300000 1.000 1.000 

15000270 15 Barley, bran 0.600000 1.000 1.000 

15001200 15 Corn, field, flour 0.200000 1.000 1.000 

15001201 15 Corn, field, flour-babyfood 0.200000 1.000 1.000 

15001210 15 Corn, field, meal 0.200000 1.000 1.000 

15001211 15 Corn, field, meal-babyfood 0.200000 1.000 1.000 

15001220 15 Corn, field, bran 0.200000 1.000 1.000 

15001230 15 Corn, field, starch 0.200000 1.000 1.000 

15001231 15 Corn, field, starch-babyfood 0.200000 1.000 1.000 

15001240 15 Corn, field, syrup 0.200000 1.500 1.000 

15001241 15 Corn, field, syrup-babyfood 0.200000 1.500 1.000 

15001250 15 Corn, field, oil 0.200000 1.000 1.000 

15001251 15 Corn, field, oil-babyfood 0.200000 1.000 1.000 

15001260 15 Corn, pop 0.200000 1.000 1.000 

15001270 15 Corn, sweet 0.100000 1.000 1.000 

15001271 15 Corn, sweet-babyfood 0.100000 1.000 1.000 

15002310 15 Oat, bran 0.600000 1.000 1.000 

15002320 15 Oat, flour 0.300000 1.000 1.000 

15002321 15 Oat, flour-babyfood 0.300000 1.000 1.000 

15002330 15 Oat, groats/rolled oats 0.300000 1.000 1.000 

15002331 15 Oat, groats/rolled oats-babyfood 0.300000 1.000 1.000 

15003230 15 Rice, white 7.000000 1.000 1.000 

15003231 15 Rice, white-babyfood 7.000000 1.000 1.000 

15003240 15 Rice, brown 7.000000 1.000 1.000 

15003241 15 Rice, brown-babyfood 7.000000 1.000 1.000 

15003250 15 Rice, flour 7.000000 1.000 1.000 

15003251 15 Rice, flour-babyfood 7.000000 1.000 1.000 

15003260 15 Rice, bran 15.000000 1.000 1.000 

15003261 15 Rice, bran-babyfood 15.000000 1.000 1.000 

15003280 15 Rye, grain 0.300000 1.000 1.000 

15003290 15 Rye, flour 0.300000 1.000 1.000 

15003440 15 Sorghum, grain 3.500000 1.000 1.000 

15003450 15 Sorghum, syrup 3.500000 1.000 1.000 

15004010 15 Wheat, grain 0.300000 1.000 1.000 

15004011 15 Wheat, grain-babyfood 0.300000 1.000 1.000 

15004020 15 Wheat, flour 0.300000 1.000 1.000 

15004021 15 Wheat, flour-babyfood 0.300000 1.000 1.000 

15004030 15 Wheat, germ 0.300000 1.000 1.000 

15004040 15 Wheat, bran 0.600000 1.000 1.000 

15004050 15 Wild rice 0.500000 1.000 1.000 

19012490 19A Parsley, dried leaves 35.000000 1.000 1.000 

19012491 19A Parsley, dried leaves-babyfood 35.000000 1.000 1.000 

 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

______________________________________________________________________________________

Page 16 of 20 

Attachment 2. Acute Results file. 

U.S. Environmental Protection Agency Ver. 2.02 

DEEM-FCID ACUTE Analysis for PROPICONAZOLE (1994-98 data) 

Residue file: 122101 Acute 7-2010 Sec 18 Avocado.R98 

 Adjustment factor #2 used. 

Analysis Date: 07-20-2010/09:02:20 Residue file dated: 07-20-2010/08:59:29/8 

Daily totals for food and foodform consumption used. 

Run Comment: "" 

=============================================================================== 

Summary calculations (per capita): 

 95th Percentile 99th Percentile 99.9th Percentile 

 Exposure % aRfD Exposure % aRfD Exposure % aRfD 

 ---------- -------- ---------- -------- ---------- -------- 

U.S. Population: 

 0.022027 7.34 0.043031 14.34 0.103143 34.38 

All infants: 

 0.048208 16.07 0.092614 30.87 0.193255 64.42 

Children 1-2 yrs: 

 0.051511 17.17 0.107628 35.88 0.227469 75.82 

Children 3-5 yrs: 

 0.039625 13.21 0.078240 26.08 0.165767 55.26 

Children 6-12 yrs: 

 0.027151 9.05 0.048646 16.22 0.091310 30.44 

Youth 13-19 yrs: 

 0.018019 6.01 0.037944 12.65 0.063133 21.04 

Adults 20-49 yrs: 

 0.017908 5.97 0.033322 11.11 0.089665 29.89 

Adults 50+ yrs: 

 0.013500 4.50 0.025841 8.61 0.050482 16.83 

Females 13-49 yrs: 

 0.016757 5.59 0.030951 10.32 0.093153 31.05 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

______________________________________________________________________________________

Page 17 of 20 

Attachment 3. Chronic Food plus Water Residue Input file.

Filename: C:\Documents and Settings\tmorton\My Documents\MyFiles\DEEM Files\122101 

Propiconazole\Section 18 Avocado\122101 Chronic 7-2010 Sec 18 Avocado.R98 

Chemical: Propiconazole 

RfD(Chronic): .1 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day 

RfD(Acute): .3 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day 

Date created/last modified: 07-14-2010/14:07:38/8 Program ver. 2.03 

-------------------------------------------------------------------------------- 

 EPA Crop Def Res Adj.Factors Comment 

 Code Grp Commodity Name (ppm) #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ ------- 

95000200 O Avocado 10.000000 1.000 1.000 

95000230 O Banana 0.200000 1.000 1.000 

95000231 O Banana-babyfood 0.200000 1.000 1.000 

95000240 O Banana, dried 0.200000 3.900 1.000 

95000241 O Banana, dried-babyfood 0.200000 3.900 1.000 

95001300 O Cranberry 1.000000 1.000 1.000 

95001301 O Cranberry-babyfood 1.000000 1.000 1.000 

95001310 O Cranberry, dried 1.000000 1.000 1.000 

95001320 O Cranberry, juice 1.000000 1.100 1.000 

95001321 O Cranberry, juice-babyfood 1.000000 1.100 1.000 

95002280 O Mushroom 0.100000 1.000 1.000 

95002630 O Peanut 0.200000 1.000 1.000 

95002640 O Peanut, butter 0.200000 1.890 1.000 

95002650 O Peanut, oil 0.200000 1.000 1.000 

95002750 O Peppermint 3.500000 1.000 1.000 

95002760 O Peppermint, oil 3.500000 1.000 1.000 

95002790 O Pineapple 4.500000 1.000 1.000 

95002791 O Pineapple-babyfood 4.500000 1.000 1.000 

95002800 O Pineapple, dried 4.500000 5.000 1.000 

95002810 O Pineapple, juice 4.500000 1.700 1.000 

95002811 O Pineapple, juice-babyfood 4.500000 1.700 1.000 

95002830 O Plantain 0.200000 1.000 1.000 

95002840 O Plantain, dried 0.200000 3.900 1.000 

95003520 O Spearmint 3.500000 1.000 1.000 

95003530 O Spearmint, oil 3.500000 1.000 1.000 

95003590 O Strawberry 1.300000 1.000 1.000 

95003591 O Strawberry-babyfood 1.300000 1.000 1.000 

95003600 O Strawberry, juice 1.300000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 1.300000 1.000 1.000 

86010000 O Water, direct, all sources 0.021610 1.000 1.000 

86020000 O Water, indirect, all sources 0.021610 1.000 1.000 

21000440 M Beef, meat 0.050000 1.000 1.000 

21000441 M Beef, meat-babyfood 0.050000 1.000 1.000 

21000450 M Beef, meat, dried 0.050000 1.920 1.000 

21000460 M Beef, meat byproducts 0.050000 1.000 1.000 

21000461 M Beef, meat byproducts-babyfood 0.050000 1.000 1.000 

21000470 M Beef, fat 0.050000 1.000 1.000 

21000471 M Beef,fat-babyfood 0.050000 1.000 1.000 

21000480 M Beef, kidney 2.000000 1.000 1.000 

21000490 M Beef, liver 2.000000 1.000 1.000 

21000491 M Beef, liver-babyfood 2.000000 1.000 1.000 

23001690 M Goat, meat 0.050000 1.000 1.000 

23001700 M Goat, meat byproducts 0.050000 1.000 1.000 

23001710 M Goat, fat 0.050000 1.000 1.000 

23001720 M Goat, kidney 2.000000 1.000 1.000 

23001730 M Goat, liver 2.000000 1.000 1.000 

24001890 M Horse, meat 0.050000 1.000 1.000 

25002940 M Pork, kidney 0.200000 1.000 1.000 

25002950 M Pork, liver 0.200000 1.000 1.000 

26003390 M Sheep, meat 0.050000 1.000 1.000 

26003391 M Sheep, meat-babyfood 0.050000 1.000 1.000 

26003400 M Sheep, meat byproducts 0.050000 1.000 1.000 

26003410 M Sheep, fat 0.050000 1.000 1.000 

26003411 M Sheep, fat-babyfood 0.050000 1.000 1.000 

26003420 M Sheep, kidney 2.000000 1.000 1.000 

26003430 M Sheep, liver 2.000000 1.000 1.000 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

______________________________________________________________________________________

Page 18 of 20 

27002220 D Milk, fat 0.050000 1.000 1.000 

27002221 D Milk, fat - baby food/infant for 0.050000 1.000 1.000 

27012230 D Milk, nonfat solids 0.050000 1.000 1.000 

27012231 D Milk, nonfat solids-baby food/in 0.050000 1.000 1.000 

27022240 D Milk, water 0.050000 1.000 1.000 

27022241 D Milk, water-babyfood/infant form 0.050000 1.000 1.000 

27032251 D Milk, sugar (lactose)-baby food/ 0.050000 1.000 1.000 

01010500 1AB Beet, garden, roots 0.300000 1.000 1.000 

01010501 1AB Beet, garden, roots-babyfood 0.300000 1.000 1.000 

01010520 1A Beet, sugar 0.300000 1.000 1.000 

01010521 1A Beet, sugar-babyfood 0.300000 1.000 1.000 

01010530 1A Beet, sugar, molasses 1.500000 1.000 1.000 

01010531 1A Beet, sugar, molasses-babyfood 1.500000 1.000 1.000 

01010780 1AB Carrot 0.250000 1.000 1.000 

01010781 1AB Carrot-babyfood 0.250000 1.000 1.000 

01010790 1AB Carrot, juice 0.250000 1.000 1.000 

02000510 2 Beet, garden, tops 5.500000 1.000 1.000 

03002370 3 Onion, dry bulb 0.200000 1.000 1.000 

03002371 3 Onion, dry bulb-babyfood 0.200000 1.000 1.000 

03002380 3 Onion, dry bulb, dried 0.200000 9.000 1.000 

03002381 3 Onion, dry bulb, dried-babyfood 0.200000 9.000 1.000 

03002390 3 Onion, green 9.000000 1.000 1.000 

04020760 4B Cardoon 5.000000 1.000 1.000 

04020850 4B Celery 5.000000 1.000 1.000 

04020851 4B Celery-babyfood 5.000000 1.000 1.000 

04020860 4B Celery, juice 5.000000 1.000 1.000 

04020870 4B Celtuce 5.000000 1.000 1.000 

04021520 4B Fennel, Florence 5.000000 1.000 1.000 

04012480 4A Parsley, leaves 13.000000 1.000 1.000 

04023220 4B Rhubarb 5.000000 1.000 1.000 

04023670 4B Swiss chard 5.000000 1.000 1.000 

06003470 6 Soybean, seed 2.000000 1.000 1.000 

06003480 6 Soybean, flour 2.000000 1.000 1.000 

06003481 6 Soybean, flour-babyfood 2.000000 1.000 1.000 

06003490 6 Soybean, soy milk 2.000000 1.000 1.000 

06003491 6 Soybean, soy milk-babyfood or in 2.000000 1.000 1.000 

06003500 6 Soybean, oil 2.000000 1.000 1.000 

06003501 6 Soybean, oil-babyfood 2.000000 1.000 1.000 

12000120 12 Apricot 1.000000 1.000 1.000 

12000121 12 Apricot-babyfood 1.000000 1.000 1.000 

12000130 12 Apricot, dried 1.000000 6.000 1.000 

12000140 12 Apricot, juice 1.000000 1.000 1.000 

12000141 12 Apricot, juice-babyfood 1.000000 1.000 1.000 

12000900 12 Cherry 1.000000 1.000 1.000 

12000901 12 Cherry-babyfood 1.000000 1.000 1.000 

12000910 12 Cherry, juice 1.000000 1.500 1.000 

12000911 12 Cherry, juice-babyfood 1.000000 1.500 1.000 

12002300 12 Nectarine 2.000000 1.000 1.000 

12002600 12 Peach 2.000000 1.000 1.000 

12002601 12 Peach-babyfood 2.000000 1.000 1.000 

12002610 12 Peach, dried 2.000000 7.000 1.000 

12002611 12 Peach, dried-babyfood 2.000000 7.000 1.000 

12002620 12 Peach, juice 2.000000 1.000 1.000 

12002621 12 Peach, juice-babyfood 2.000000 1.000 1.000 

12002850 12 Plum 1.000000 1.000 1.000 

12002851 12 Plum-babyfood 1.000000 1.000 1.000 

12002860 12 Plum, prune, fresh 1.000000 1.000 1.000 

12002861 12 Plum, prune, fresh-babyfood 1.000000 1.000 1.000 

12002870 12 Plum, prune, dried 1.000000 5.000 1.000 

12002871 12 Plum, prune, dried-babyfood 1.000000 5.000 1.000 

12002880 12 Plum, prune, juice 1.000000 1.400 1.000 

12002881 12 Plum, prune, juice-babyfood 1.000000 1.400 1.000 

13010550 13A Blackberry 1.000000 1.000 1.000 

13010560 13A Blackberry, juice 1.000000 1.000 1.000 

13010561 13A Blackberry, juice-babyfood 1.000000 1.000 1.000 

13020570 13B Blueberry 1.000000 1.000 1.000 

13020571 13B Blueberry-babyfood 1.000000 1.000 1.000 

13010580 13A Boysenberry 1.000000 1.000 1.000 

13021360 13B Currant 1.000000 1.000 1.000 

13021370 13B Currant, dried 1.000000 1.000 1.000 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

______________________________________________________________________________________

Page 19 of 20 

13011420 13A Dewberry 1.000000 1.000 1.000 

13021490 13B Elderberry 1.000000 1.000 1.000 

13021740 13B Gooseberry 1.000000 1.000 1.000 

13021910 13B Huckleberry 1.000000 1.000 1.000 

13012080 13A Loganberry 1.000000 1.000 1.000 

13013200 13A Raspberry 1.000000 1.000 1.000 

13013201 13A Raspberry-babyfood 1.000000 1.000 1.000 

13013210 13A Raspberry, juice 1.000000 1.000 1.000 

13013211 13A Raspberry, juice-babyfood 1.000000 1.000 1.000 

14000030 14 Almond 0.100000 1.000 1.000 

14000031 14 Almond-babyfood 0.100000 1.000 1.000 

14000040 14 Almond, oil 0.100000 1.000 1.000 

14000041 14 Almond, oil-babyfood 0.100000 1.000 1.000 

14000590 14 Brazil nut 0.100000 1.000 1.000 

14000680 14 Butternut 0.100000 1.000 1.000 

14000810 14 Cashew 0.100000 1.000 1.000 

14000920 14 Chestnut 0.100000 1.000 1.000 

14001550 14 Filbert 0.100000 1.000 1.000 

14001560 14 Filbert, oil 0.100000 1.000 1.000 

14001850 14 Hickory nut 0.100000 1.000 1.000 

14002130 14 Macadamia nut 0.100000 1.000 1.000 

14002690 14 Pecan 0.100000 1.000 1.000 

14002820 14 Pistachio 0.100000 1.000 1.000 

14003910 14 Walnut 0.100000 1.000 1.000 

15000250 15 Barley, pearled barley 0.300000 1.000 1.000 

15000251 15 Barley, pearled barley-babyfood 0.300000 1.000 1.000 

15000260 15 Barley, flour 0.300000 1.000 1.000 

15000261 15 Barley, flour-babyfood 0.300000 1.000 1.000 

15000270 15 Barley, bran 0.600000 1.000 1.000 

15001200 15 Corn, field, flour 0.200000 1.000 1.000 

15001201 15 Corn, field, flour-babyfood 0.200000 1.000 1.000 

15001210 15 Corn, field, meal 0.200000 1.000 1.000 

15001211 15 Corn, field, meal-babyfood 0.200000 1.000 1.000 

15001220 15 Corn, field, bran 0.200000 1.000 1.000 

15001230 15 Corn, field, starch 0.200000 1.000 1.000 

15001231 15 Corn, field, starch-babyfood 0.200000 1.000 1.000 

15001240 15 Corn, field, syrup 0.200000 1.500 1.000 

15001241 15 Corn, field, syrup-babyfood 0.200000 1.500 1.000 

15001250 15 Corn, field, oil 0.200000 1.000 1.000 

15001251 15 Corn, field, oil-babyfood 0.200000 1.000 1.000 

15001260 15 Corn, pop 0.200000 1.000 1.000 

15001270 15 Corn, sweet 0.100000 1.000 1.000 

15001271 15 Corn, sweet-babyfood 0.100000 1.000 1.000 

15002310 15 Oat, bran 0.600000 1.000 1.000 

15002320 15 Oat, flour 0.300000 1.000 1.000 

15002321 15 Oat, flour-babyfood 0.300000 1.000 1.000 

15002330 15 Oat, groats/rolled oats 0.300000 1.000 1.000 

15002331 15 Oat, groats/rolled oats-babyfood 0.300000 1.000 1.000 

15003230 15 Rice, white 7.000000 1.000 1.000 

15003231 15 Rice, white-babyfood 7.000000 1.000 1.000 

15003240 15 Rice, brown 7.000000 1.000 1.000 

15003241 15 Rice, brown-babyfood 7.000000 1.000 1.000 

15003250 15 Rice, flour 7.000000 1.000 1.000 

15003251 15 Rice, flour-babyfood 7.000000 1.000 1.000 

15003260 15 Rice, bran 15.000000 1.000 1.000 

15003261 15 Rice, bran-babyfood 15.000000 1.000 1.000 

15003280 15 Rye, grain 0.300000 1.000 1.000 

15003290 15 Rye, flour 0.300000 1.000 1.000 

15003440 15 Sorghum, grain 3.500000 1.000 1.000 

15003450 15 Sorghum, syrup 3.500000 1.000 1.000 

15004010 15 Wheat, grain 0.300000 1.000 1.000 

15004011 15 Wheat, grain-babyfood 0.300000 1.000 1.000 

15004020 15 Wheat, flour 0.300000 1.000 1.000 

15004021 15 Wheat, flour-babyfood 0.300000 1.000 1.000 

15004030 15 Wheat, germ 0.300000 1.000 1.000 

15004040 15 Wheat, bran 0.600000 1.000 1.000 

15004050 15 Wild rice 0.500000 1.000 1.000 

19012490 19A Parsley, dried leaves 35.000000 1.000 1.000 

19012491 19A Parsley, dried leaves-babyfood 35.000000 1.000 1.000 
 Propiconazole Dietary Exposure and Risk Assessment DP Number: D380158 

PC Code: 122101 

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Page 20 of 20 

Attachment 4. Chronic Results file.

U.S. Environmental Protection Agency Ver. 2.00 

DEEM-FCID Chronic analysis for PROPICONAZOLE (1994-98 data) 

Residue file name: C:\Documents and Settings\tmorton\My Documents\MyFiles\DEEM 

Files\122101 Propiconazole\Section 18 Avocado\122101 Chronic 7-2010 Sec 18 Avocado.R98 

 Adjustment factor #2 NOT used. 

Analysis Date 07-14-2010/15:28:45 Residue file dated: 07-14-2010/14:07:38/8 

Reference dose (RfD, Chronic) = .1 mg/kg bw/day 

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 Total exposure by population subgroup 

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 Total Exposure 

 ----------------------------------- 

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- --------------- 

U.S. Population (total) 0.006790 6.8% 

U.S. Population (spring season) 0.006888 6.9% 

U.S. Population (summer season) 0.007037 7.0% 

U.S. Population (autumn season) 0.006501 6.5% 

U.S. Population (winter season) 0.006746 6.7% 

Northeast region 0.007054 7.1% 

Midwest region 0.006275 6.3% 

Southern region 0.006068 6.1% 

Western region 0.008247 8.2% 

Hispanics 0.009079 9.1% 

Non-hispanic whites 0.005984 6.0% 

Non-hispanic blacks 0.006701 6.7% 

Non-hisp/non-white/non-black 0.014796 14.8% 

All infants (< 1 year) 0.015833 15.8% 

Nursing infants 0.008261 8.3% 

Non-nursing infants 0.018707 18.7% 

Children 1-6 yrs 0.015484 15.5% 

Children 7-12 yrs 0.009148 9.1% 

Females 13-19 (not preg or nursing) 0.005167 5.2% 

Females 20+ (not preg or nursing) 0.004913 4.9% 

Females 13-50 yrs 0.005821 5.8% 

Females 13+ (preg/not nursing) 0.007132 7.1% 

Females 13+ (nursing) 0.007977 8.0% 

Males 13-19 yrs 0.006551 6.6% 

Males 20+ yrs 0.005585 5.6% 

Seniors 55+ 0.004485 4.5% 

Children 1-2 yrs 0.018203 18.2% 

Children 3-5 yrs 0.014752 14.8% 

Children 6-12 yrs 0.009621 9.6% 

Youth 13-19 yrs 0.005886 5.9% 

Adults 20-49 yrs 0.005682 5.7% 

Adults 50+ yrs 0.004553 4.6% 

Females 13-49 yrs 0.005366 5.4% 

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