I 

118TH CONGRESS 

1ST SESSION H. R. 120 

To direct that certain assessments with respect to toxicity of chemicals be 

carried out by the program offices of the Environmental Protection 

Agency, and for other purposes. 

IN THE HOUSE OF REPRESENTATIVES 

JANUARY 9, 2023 

Mr. BIGGS introduced the following bill; which was referred to the Committee 

on Science, Space, and Technology, and in addition to the Committee on 

Energy and Commerce, for a period to be subsequently determined by the 

Speaker, in each case for consideration of such provisions as fall within 

the jurisdiction of the committee concerned 

A BILL 

To direct that certain assessments with respect to toxicity 

of chemicals be carried out by the program offices of 

the Environmental Protection Agency, and for other purposes. 

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled, 

3 SECTION 1. SHORT TITLE. 

4 This Act may be cited as the ‘‘Improving Science in 

5 Chemical Assessments Act’’. 


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1 SEC. 2. RESEARCH NEEDS AND PRIORITIES OF EPA PRO2 GRAM OFFICES. 

3 The Environmental Research, Development, and 

4 Demonstration Authorization Act of 1978 is amended by 

5 striking section 7 (42 U.S.C. 4364) and inserting the fol6 lowing new sections: 

7 ‘‘SEC. 7. RESEARCH NEEDS AND PRIORITIES OF EPA PRO8 GRAM OFFICES. 

9 ‘‘(a) IN GENERAL.—The Administrator of the Envi10 ronmental Protection Agency shall assure that the expend11 iture of any funds appropriated pursuant to this Act or 

12 any other provision of law for environmental research and 

13 development related to regulatory program activities shall 

14 be coordinated with and reflect the research needs and pri15 orities of the relevant program offices, as well as the over16 all research needs and priorities of the Agency, including 

17 those defined in the five-year research plan. 

18 ‘‘(b) HAZARD IDENTIFICATION AND DOSE-RESPONSE

19 ASSESSMENTS.—Beginning on the date of the enactment 

20 of the Improving Science in Chemical Assessments Act, 

21 any covered assessments carried out with respect to a 

22 chemical substance through the Integrated Risk Informa23 tion System program of the Environmental Protection 

24 Agency as of the day before such date of enactment shall, 

25 in lieu of being carried out through such program, be car26 ried out by the relevant program office of the EnvironVerDate Sep 11 2014 00:47 Jan 18, 2023 Jkt 039200 PO 00000 Frm 00002 Fmt 6652 Sfmt 6201 E:\BILLS\H120.IH H120

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1 mental Protection Agency, so long as the relevant program 

2 office determines there is a need for such an assessment. 

3 Such an assessment shall be carried out using the sci4 entific standards specified in section 7B and be based on 

5 the weight of the scientific evidence. 

6 ‘‘(c) TOXICITY VALUES.—In carrying out a covered 

7 assessment with respect to a chemical substance under 

8 subsection (b), the relevant program office shall assign a 

9 toxicity value or values, when scientifically supported by 

10 the available data, for such chemical substance. With re11 spect to that assignment, the following shall apply: 

12 ‘‘(1) When supported by the available data, the 

13 toxicity value or values shall include a range of point 

14 estimates of risk, as well as sources and magnitudes 

15 of uncertainty associated with the estimates. 

16 ‘‘(2) When multiple point estimates can be de17 veloped, the relevant program office shall— 

18 ‘‘(A) consider all datasets; and 

19 ‘‘(B) make a determination about how best 

20 to represent the human health risk posed by the 

21 chemical substance involved. 

22 ‘‘(d) CHEMICAL ASSESSMENT DATABASE.— 

23 ‘‘(1) IN GENERAL.—A toxicity value or values 

24 assigned to a chemical substance under subsection 

25 (c) shall be included in a chemical assessment dataVerDate Sep 11 2014 00:47 Jan 18, 2023 Jkt 039200 PO 00000 Frm 00003 Fmt 6652 Sfmt 6201 E:\BILLS\H120.IH H120

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1 base to be maintained by the Office of Research and 

2 Development of the Environmental Protection Agen3 cy. 

4 ‘‘(2) COMPLETED ASSESSMENTS.—All covered 

5 assessments stored, as of the date of the enactment 

6 of this Act, in the IRIS database of the Environ7 mental Protection Agency shall be retained in the 

8 chemical assessment database established pursuant 

9 to paragraph (1). 

10 ‘‘(3) UPDATES.—Such database shall be up11 dated pursuant to a covered assessment performed 

12 by a relevant program office, including to make a 

13 change in the existing toxicity value or values for a 

14 chemical substance included in such database. 

15 ‘‘(e) CERTIFICATION.—Beginning 2 years after the 

16 date of the enactment of the Improving Science in Chem17 ical Assessments Act and every 2 years thereafter, the Of18 fice of Research and Development of the Environmental 

19 Protection Agency shall submit to the Committee on 

20 Science, Space, and Technology and the Committee on 

21 Energy and Commerce of the House of Representatives 

22 and the Committee on Environment and Public Works of 

23 the Senate a report containing a certification that each 

24 covered assessment completed during the period covered 


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1 by the report was conducted using the scientific standards 

2 specified in section 7B. 

3 ‘‘(f) DEFINITIONS.—In this section, section 7A, and 

4 section 7B: 

5 ‘‘(1) COVERED ASSESSMENT.—The term ‘cov6 ered assessment’ means, with respect to the evalua7 tion of the human health effects resulting from 

8 chronic exposure to a chemical substance, a chemical 

9 hazard identification and dose-response assessment 

10 (as such terms are defined by the Environmental 

11 Protection Agency on the day before the date of the 

12 enactment of this section). 

13 ‘‘(2) RELEVANT PROGRAM OFFICE.—The term 

14 ‘relevant program office’ includes the following of15 fices of the Environmental Protection Agency: 

16 ‘‘(A) The Office of Water. 

17 ‘‘(B) The Office of Air and Radiation. 

18 ‘‘(C) The Office of Land and Emergency 

19 Management. 

20 ‘‘(D) The Office of Chemical Safety and 

21 Pollution Prevention. 

22 ‘‘(E) Any successor to an office specified in 

23 subparagraphs (A) through (D) and any other 

24 office determined to be relevant by the Adminis25 trator of the Environmental Protection Agency. 


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1 ‘‘SEC. 7A. HAZARD IDENTIFICATION AND DOSE-RESPONSE 

2 STEERING COMMITTEE. 

3 ‘‘(a) ESTABLISHMENT.—Not later than 30 days after 

4 the date of the enactment of the Improving Science in 

5 Chemical Assessments Act, the Administrator of the Envi6 ronmental Protection Agency shall establish a chemical 

7 hazard identification and dose-response steering com8 mittee (referred to in this section as the ‘steering com9 mittee’) to coordinate the conduct of covered assessments 

10 by relevant program offices for purposes of ensuring that, 

11 with respect to such assessments, there is no duplication 

12 of effort by such offices. 

13 ‘‘(b) DUTY.—The duties of the steering committee 

14 are the following: 

15 ‘‘(1) If the steering committee learns that more 

16 than one relevant program office intends to conduct 

17 covered assessments with respect to the same chem18 ical substance, the steering committee shall deter19 mine the most effective means of carrying out a sin20 gle covered assessment to prevent duplication of ef21 fort by such offices. 

22 ‘‘(2) For purposes of supplementing a covered 

23 assessment, the steering committee shall consider 

24 any third-party assessment of a chemical substance 

25 generated by another Federal, State, or inter26 national agency or agencies or members of the sciVerDate Sep 11 2014 00:47 Jan 18, 2023 Jkt 039200 PO 00000 Frm 00006 Fmt 6652 Sfmt 6201 E:\BILLS\H120.IH H120

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1 entific community that meets the requirements spec2 ified in subsection (e). 

3 ‘‘(c) CHAIR; COMPOSITION.— 

4 ‘‘(1) CHAIR.—The steering committee shall be 

5 chaired by the Assistant Administrator of the Office 

6 of Research and Development of the Environmental 

7 Protection Agency. 

8 ‘‘(2) COMPOSITION.—The steering committee 

9 shall be composed of 15 members, all of whom shall 

10 be active, full-time employees of the Environmental 

11 Protection Agency, with at least one member rep12 resenting each relevant program office and each re13 gional office of the Environmental Protection Agen14 cy. The members of the steering committee shall be 

15 appointed by the Administrator of the Environ16 mental Protection Agency. Any vacancy shall be 

17 filled in the same manner as the initial appointment. 

18 ‘‘(d) MEETINGS.—The steering committee shall meet 

19 at least once each calendar year. 

20 ‘‘(e) THIRD-PARTY ASSESSMENT REQUIREMENTS.— 

21 The requirements specified in this subsection with respect 

22 to a third-party assessment of a chemical substance are 

23 that the assessment— 

24 ‘‘(1) is conducted using scientific standards 

25 specified in section 7B; 


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1 ‘‘(2) has undergone independent scientific re2 view for transparency, completeness, and quality; 

3 and 

4 ‘‘(3) reflects the best available science and the 

5 weight of the available scientific evidence. 

6 ‘‘SEC. 7B. SCIENTIFIC STANDARDS. 

7 ‘‘Covered assessments carried out under section 7 

8 and discussion of such assessments and review of third9 party assessments carried out under section 7A shall be 

10 conducted using scientific information, technical proce11 dures, measures, methods, protocols, methodologies, or 

12 models in a manner consistent with the best available 

13 science. In carrying out such an assessment, the relevant 

14 program office shall integrate all lines of scientific evi15 dence and consider, as applicable, the following: 

16 ‘‘(1) The extent to which the scientific informa17 tion, technical procedures, measures, methods, proto18 cols, methodologies, or models employed to generate 

19 the scientific information are reasonable for and con20 sistent with the intended use of the scientific infor21 mation. 

22 ‘‘(2) The extent to which the scientific informa23 tion is relevant for the relevant program office’s use 

24 in making a decision regarding a chemical sub25 stance. 


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1 ‘‘(3) The degree of clarity and completeness 

2 with which the data, assumptions, methods, quality 

3 assurance, and analyses employed to generate the 

4 scientific information are documented and publicly 

5 available in a manner that honors legal and ethical 

6 obligations to reduce the risks of unauthorized dis7 closure and re-identification. 

8 ‘‘(4) The extent to which the variability and un9 certainty in the scientific information, or in the pro10 cedures, measures, methods, protocols, methodolo11 gies, or models, are evaluated and characterized. 

12 ‘‘(5) The extent of independent verification or 

13 peer review of the scientific information or of the 

14 procedures, measures, methods, protocols, meth15 odologies, or models. 

16 ‘‘(6) The ability of the scientific findings and 

17 research to be replicated or reproduced. 

18 ‘‘(7) The extent to which the available scientific 

19 information supports dose-response modeling, using 

20 non-linear approaches.’’. 

Æ 


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