July 2013 ATSDR Minimal Risk Levels Page 1 of 14 

Agency for Toxic Substances and Disease Registry

Minimal Risk Levels (MRLs)

July 2013 

 Dura- Uncertainty Cover CAS

Name Route tion MRL Factors Endpoint Status Date Number

______________________________________________________________________________________________________________

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ACENAPHTHENE Oral Int. 0.6 mg/kg/day 300 Hepatic Final 08/95 83-32-9 

ACETONE 

 

 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Int. 

26 ppm 

13 ppm 

13 ppm 

2 mg/kg/day 

9 Neurol. 

100 Neurol.

100 Neurol.

100 Hemato.

Final 05/94 67-64-1 

ACROLEIN 

 

 

Inh. 

Oral 

Acute 

Int. 

Int. 

0.003 ppm 

0.00004 ppm 

0.004 mg/kg/day 

100 Resp. 

300 Resp.

100 Gastro.

Final 08/07 107-02-8 

ACRYLAMIDE 

 

 

 

 

 

Oral Acute 

Int. 

Chr. 

0.01 mg/kg/day 

0.001 mg/kg/day 

0.001 mg/kg/day 

30 Repro. 

30 Neurol.

30 Neurol.

Final 12/12 79-06-1 

ACRYLONITRILE 

 

 

 Inh. 

Oral 

Acute 

Acute 

Int. 

Chr. 

0.1 ppm 

0.1 mg/kg/day 

0.01 mg/kg/day 

0.04 mg/kg/day 

10 Neurol. 

100 Develop.

1000 Repro.

100 Hemato.

Final 12/90 107-13-1 

ALDRIN 

 

Oral Acute 

Chr. 

0.002 mg/kg/day 

0.00003 mg/kg/day 

1000 

1000 

Develop. 

Hepatic

Final 09/02 309-00-2 

ALUMINUM 

 

Oral Int. 

Chr. 

1.0 mg/kg/day 

1.0 mg/kg/day 

30 

90 

Neurol. 

Neurol.

Final 09/08 7429-90-5 

AMERICIUM 

 

Rad. Acute 

Chr. 

4 mSv 

1 mSv/yr 

3 

3 

Develop. 

Other

Final 10/04 7440-35-9 

AMMONIA 

 

Inh. Acute 

Chr. 

1.7 ppm 

0.1 ppm 

30 

30 

Resp. 

Resp.

Final 10/04 7664-41-7 

ANTHRACENE Oral Int. 10 mg/kg/day 100 Hepatic Final 08/95 120-12-7 
July 2013 ATSDR Minimal Risk Levels Page 2 of 14 

ARSENIC 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Oral Acute 

Chr. 

0.005 mg/kg/day 

0.0003 mg/kg/day 

10 Gastro. 

3 Dermal

Final 08/07 7440-38-2 

ATRAZINE 

 

Oral Acute 

Int. 

0.01 mg/kg/day 

0.003 mg/kg/day 

100 Body Wt. 

300 Repro.

Final 09/03 1912-24-9 

BARIUM, SOLUBLE SALTS 

 

Oral Int. 

Chr. 

0.2 mg/kg/day 

0.2 mg/kg/day 

100 Renal 

100 Renal

Final 08/07 7440-39-3 

BENZENE 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Chr. 

0.009 ppm 

0.006 ppm 

0.003 ppm 

0.0005 mg/kg/day 

300 Immuno. 

300 Immuno.

10 Immuno.

30 Immuno.

Final 08/07 71-43-2 

BERYLLIUM Oral Chr. 0.002 mg/kg/day 300 Gastro. Final 09/02 7440-41-7 

BIS(2-CHLOROETHYL) ETHER Inh. Int. 0.02 ppm 1000 Body Wt. Final 12/89 111-44-4 

BIS(CHLOROMETHYL) ETHER Inh. Int. 0.0003 ppm 100 Resp. Final 12/89 542-88-1 

BORON 

 

 

Inh. 

Oral 

Acute 

Acute 

Int. 

0.3 mg/m3 

0.2 mg/kg/day 

0.2 mg/kg/day 

 3 Resp. 

100 Develop.

66 Develop.

Final 11/10 7440-42-8 

BROMODICHLOROMETHANE 

 

Oral Acute 

Chr. 

0.04 mg/kg/day 

0.02 mg/kg/day 

1000 Hepatic 

1000 Renal

Final 12/89 75-27-4 

BROMOFORM 

 

Oral Acute 

Int. 

Chr. 

0.7 mg/kg/day 

0.2 mg/kg/day 

0.02 mg/kg/day 

100 Hepatic 

300 Hepatic

3000 Hepatic

Final 09/05 75-25-2 

BROMOMETHANE 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Int. 

0.05 ppm 

0.05 ppm 

0.005 ppm 

0.003 mg/kg/day 

100 Neurol. 

100 Neurol.

100 Neurol.

100 Gastro.

Final 09/92 74-83-9 

2-BUTOXYETHANOL 

 (ETHYLENE GLYCOL MONOBUTYL ETHER) 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Acute 

Int. 

6 ppm 

3 ppm 

0.2 ppm 

0.4 mg/kg/day 

0.07 mg/kg/day 

9 

9 

3 

90 

1000 

Hemato. 

Hemato.

Hemato.

Hemato.

Hepatic

Final 10/98 111-76-2 

CADMIUM 

 

Inh. Acute 

Chr. 

0.00003 mg/m3 

0.00001 mg/m3 

300 Resp. 

9 Renal

Final 09/12 7440-43-9 
July 2013 ATSDR Minimal Risk Levels Page 3 of 14 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Oral Int. 

Chr. 

0.0005 mg/kg/day 

0.0001 mg/kg/day 

100 Musculo.

3 Renal

CARBON DISULFIDE 

 

Inh. 

Oral 

Chr. 

Acute 

0.3 ppm 

0.01 mg/kg/day 

30 Neurol. 

300 Hepatic

Final 08/96 75-15-0 

CARBON TETRACHLORIDE 

 

 

Inh. 

Oral 

Int. 

Chr. 

Acute 

Int. 

0.03 ppm 

0.03 ppm 

0.02 mg/kg/day 

0.007 mg/kg/day 

30 Hepatic 

30 Hepatic

300 Hepatic

100 Hepatic

Final 09/05 56-23-5 

CESIUM 

 

Rad. Acute 

Chr. 

4 mSv 

1 mSv/yr 

3 Develop. 

3 Other

Final 10/04 7440-46-2 

CHLORDANE 

 

 

 

Inh. 

Oral 

Int. 

Chr. 

Acute 

Int. 

Chr. 

0.0002 mg/m3 

0.00002 mg/m3 

0.001 mg/kg/day 

0.0006 mg/kg/day 

0.0006 mg/kg/day 

100 Hepatic 

1000 Hepatic

1000 Develop.

100 Hepatic

100 Hepatic

Final 05/94 57-74-9 

CHLORDECONE 

 

Oral Acute 

Int. 

Chr. 

0.01 mg/kg/day 

0.0005 mg/kg/day 

0.0005 mg/kg/day 

100 Neurol. 

100 Renal

100 Renal

Final 08/95 143-50-0 

CHLORFENVINPHOS 

 

Oral Acute 

Int. 

Chr. 

0.002 mg/kg/day 

0.002 mg/kg/day 

0.0007 mg/kg/day 

1000 Neurol. 

1000 Immuno.

1000 Neurol.

Final 09/97 470-90-6 

CHLORINE 

 

 

Inh. Acute 

Int. 

Chr. 

0.06 ppm 

0.002 ppm 

0.00005 ppm 

3 Resp. 

90 Resp.

30 Resp.

Final 11/10 7782-50-5 

CHLORINE DIOXIDE Inh. Int. 0.001 ppm 300 Resp. Final 10/04 10049-04-4 

CHLORITE Oral Int. 0.1 mg/kg/day 30 Neurol. Final 10/04 7758-19-2 

CHLOROBENZENE Oral Int. 0.4 mg/kg/day 100 Hepatic Final 12/90 108-90-7 

CHLORODIBROMOMETHANE 

 

 Oral Acute 

Chr. 

0.1 mg/kg/day 

0.09 mg/kg/day 

300 Hepatic 

300 Hepatic

Final 09/05 124-48-1 

CHLOROETHANE Inh. Acute 15 ppm 100 Develop. Final 12/98 75-00-3 
July 2013 ATSDR Minimal Risk Levels Page 4 of 14 

CHLOROFORM 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Acute 

Int. 

Chr. 

0.1 ppm 

0.05 ppm 

0.02 ppm 

0.3 mg/kg/day 

0.1 mg/kg/day 

0.01 mg/kg/day 

30 Hepatic 

300 Hepatic

100 Hepatic

100 Hepatic

100 Hepatic

1000 Hepatic

Final 09/97 67-66-3 

CHLOROMETHANE 

 

Inh. Acute 

Int. 

Chr. 

0.5 ppm 

0.2 ppm 

0.05 ppm 

100 Neurol. 

300 Hepatic

1000 Neurol.

Final 12/98 74-87-3 

4-CHLOROPHENOL Oral Acute 0.01 mg/kg/day 100 Hepatic Final 07/99 106-48-9 

CHLORPYRIFOS 

 

Oral Acute 

Int. 

Chr. 

0.003 mg/kg/day 

0.003 mg/kg/day 

0.001 mg/kg/day 

10 Neurol. 

10 Neurol.

100 Neurol.

Final 09/97 2921-88-2 

CHROMIUM(III) SOLUBLE PARTICULATES Inh. Int. 0.0001 mg/m3 300 Resp. Final 09/12 16065-83-1 

CHROMIUM(III) INSOL. PARTICULATES Inh. Int. 0.005 mg/m3 90 Resp. Final 09/12 16065-83-1 

CHROMIUM(VI) 

 

Oral Int. 

Chr. 

0.005 mg/kg/day 

0.0009 mg/kg/day 

100 Hemato. 

100 Gastro.

Final 09/12 18540-29-9 

CHROMIUM(VI), AEROSOL MISTS 

 

Inh. Int. 

Chr. 

0.000005 mg/m3 

0.000005 mg/m3 

100 Resp. 

100 Resp.

Final 09/12 18540-29-9 

CHROMIUM(VI), PARTICULATES Inh. Int. 0.0003 mg/m3 30 Resp. Final 09/12 18540-29-9 

COBALT 

 

 

Inh. 

Oral 

Rad. 

Chr. 

Int. 

Acute 

Chr. 

0.0001 mg/m3 

0.01 mg/kg/day 

4 mSv 

1 mSv/yr 

10 Resp. 

100 Hemato.

3 Develop.

3 Other

Final 10/04 7440-48-4 

COPPER 

 

Oral Acute 

Int. 

0.01 mg/kg/day 

0.01 mg/kg/day 

3 Gastro. 

3 Gastro.

Final 10/04 7440-50-8 

CRESOLS 

 

Oral Int. 

Chr. 

0.1 mg/kg/day 

0.1 mg/kg/day 

100 Resp. 

1000 Resp.

Final 09/08 1319-77-3 

CYANIDE, SODIUM Oral Int. 0.05 mg/kg/day 100 Repro. Final 07/06 143-33-9 

CYHALOTHRIN 

 

Oral Acute 

Int. 

0.01 mg/kg/day 

0.01 mg/kg/day 

100 Gastro. 

100 Gastro.

Final 09/03 68085-85-8 
July 2013 ATSDR Minimal Risk Levels Page 5 of 14 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

CYPERMETHRIN Oral Acute 0.02 mg/kg/day 100 Neurol. Final 09/03 52315-07-8 

DDT, P,P'- 

 

Oral Acute 

Int. 

0.0005 mg/kg/day 

0.0005 mg/kg/day 

1000 Develop. 

100 Hepatic

Final 09/02 50-29-3 

DIAZINON 

 

 

 

Inh. 

Oral 

Int. 

Acute 

Int. 

Chr. 

0.01 mg/m3 

0.006 mg/kg/day 

0.002 mg/kg/day 

0.0007 mg/kg/day 

30 Neurol. 

100 Neurol.

100 Neurol.

100 Neurol.

Final 09/08 333-41-5 

1,2-DIBROMO-3-CHLOROPROPANE 

 

Inh. 

Oral 

Int. 

Int. 

0.0002 ppm 

0.002 mg/kg/day 

100 Repro. 

1000 Repro.

Final 09/92 96-12-8 

DI-N-BUTYL PHTHALATE Oral Acute 0.5 mg/kg/day 100 Develop. Final 09/01 84-74-2 

1,2-DICHLOROBENZENE 

 

Oral Acute 

Int. 

Chr. 

0.7 mg/kg/day 

0.6 mg/kg/day 

0.3 mg/kg/day 

100 Hepatic 

100 Hepatic

100 Renal

Final 07/06 95-50-1 

1,3-DICHLOROBENZENE 

 

Oral Acute 

Int. 

0.4 mg/kg/day 

0.02 mg/kg/day 

100 Hepatic 

100 Endocr.

Final 07/06 541-73-1 

1,4-DICHLOROBENZENE 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Int. 

Chr. 

2 ppm 

0.2 ppm 

0.01 ppm 

0.07 mg/kg/day 

0.07 mg/kg/day 

10 Ocular 

100 Hepatic

30 Resp.

100 Hepatic

100 Hepatic

Final 07/06 106-46-7 

1,2-DICHLOROETHANE 

 

Inh. 

Oral 

Chr. 

Int. 

0.6 ppm 

0.2 mg/kg/day 

90 Hepatic 

300 Renal

Final 09/01 107-06-2 

1,1-DICHLOROETHENE 

 

Inh. 

Oral 

Int. 

Chr. 

0.02 ppm 

0.009 mg/kg/day 

100 Hepatic 

1000 Hepatic

Final 05/94 75-35-4 

1,2-DICHLOROETHENE, CIS- 

 

Oral Acute 

Int. 

1 mg/kg/day 

0.3 mg/kg/day 

100 Hemato. 

100 Hemato.

Final 08/96 156-59-2 

1,2-DICHLOROETHENE, TRANS- 

 

 

Inh. 

Oral 

Acute 

Int. 

Int. 

0.2 ppm 

0.2 ppm 

0.2 mg/kg/day 

1000 Hepatic 

1000 Hepatic

100 Hepatic

Final 08/96 156-60-5 

2,4-DICHLOROPHENOL Oral Int. 0.003 mg/kg/day 100 Immuno. Final 07/99 120-83-2 
July 2013 ATSDR Minimal Risk Levels Page 6 of 14 

1,2-DICHLOROPROPANE 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Inh. 

Oral 

Acute 

Int. 

Acute 

Int. 

Chr. 

0.05 ppm 

0.007 ppm 

0.1 mg/kg/day 

0.07 mg/kg/day 

0.09 mg/kg/day 

1000 Resp. 

1000 Resp.

1000 Neurol.

1000 Hemato.

1000 Hepatic

Final 12/89 78-87-5 

1,3-DICHLOROPROPENE 

 

 

Inh. 

Oral 

Int. 

Chr. 

Int. 

Chr. 

0.008 ppm 

0.007 ppm 

0.04 mg/kg/day 

0.03 mg/kg/day 

30 Resp. 

30 Resp.

100 Gastro.

100 Gastro.

Final 09/08 542-75-6 

2,3-DICHLOROPROPENE Inh. Acute 0.002 ppm 90 Resp. Final 09/08 78-88-6 

DICHLORVOS 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Acute 

Int. 

Chr. 

0.002 ppm 

0.0003 ppm 

0.00006 ppm 

0.004 mg/kg/day 

0.003 mg/kg/day 

0.0005 mg/kg/day 

100 Neurol. 

100 Neurol.

100 Neurol.

1000 Neurol.

10 Neurol.

100 Neurol.

Final 09/97 62-73-7 

DIELDRIN 

 

Oral Int. 

Chr. 

0.0001 mg/kg/day 

0.00005 mg/kg/day 

100 Neurol. 

100 Hepatic

Final 09/02 60-57-1 

DI(2-ETHYLHEXYL)PHTHALATE 

 

Oral Int. 

Chr. 

0.1 mg/kg/day 

0.06 mg/kg/day 

100 Repro. 

100 Repro.

Final 09/02 117-81-7 

DIETHYL PHTHALATE 

 

Oral Acute 

Int. 

7 mg/kg/day 

6 mg/kg/day 

300 Repro. 

300 Hepatic

Final 06/95 84-66-2 

DIISOPROPYL METHYLPHOSPHONATE 

(DIMP) 

Oral Int. 

Chr. 

0.8 mg/kg/day 

0.6 mg/kg/day 

100 Hemato. 

100 Hemato.

Final 10/98 1445-75-6 

DIMETHYLARSINIC ACID (DMA) Oral Chr. 0.02 mg/kg/day 100 Renal Final 08/07 75-60-5 

1,1-DIMETHYLHYDRAZINE Inh. Int. 0.0002 ppm 300 Hepatic Final 09/97 57-14-7 

1,2-DIMETHYLHYDRAZINE Oral Int. 0.0008 mg/kg/day 1000 Hepatic Final 09/97 540-73-8 

1,3-DINITROBENZENE 

 

Oral Acute 

Int. 

0.008 mg/kg/day 

0.0005 mg/kg/day 

100 Repro. 

1000 Hemato.

Final 06/95 99-65-0 

4,6-DINITRO-O-CRESOL 

 

Oral Acute 

Int. 

0.004 mg/kg/day 

0.004 mg/kg/day 

100 Neurol. 

100 Neurol.

Final 08/95 534-52-1 
July 2013 ATSDR Minimal Risk Levels Page 7 of 14 

2,4-DINITROPHENOL 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Oral Acute 0.01 mg/kg/day 100 Body Wt. Final 08/95 51-28-5 

2,4-DINITROTOLUENE 

 

Oral Acute 

Int. 

Chr. 

0.05 mg/kg/day 

0.007 mg/kg/day 

0.001 mg/kg/day 

100 Neurol. 

100 Hemato.

100 Hemato.

Draft 04/13 121-14-2 

2,6-DINITROTOLUENE 

 

 Oral Acute 

Int. 

0.09 mg/kg/day 

0.004 mg/kg/day 

100 Hemato. 

1000 Hemato.

Draft 04/13 606-20-2 

DI-N-OCTYL PHTHALATE 

 

Oral Acute 

Int. 

3 mg/kg/day 

0.4 mg/kg/day 

300 Hepatic 

100 Hepatic

Final 09/97 117-84-0 

1,4-DIOXANE 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Acute 

Int. 

Chr. 

2 ppm 

0.2 ppm 

0.03 ppm 

5 mg/kg/day 

0.5 mg/kg/day 

0.1 mg/kg/day 

30 Ocular 

30 Resp.

300 Resp.

100 Develop. 

100 Hepatic

100 Hepatic

Final 04/12 123-91-1 

DISULFOTON 

 

 

Inh. 

Oral 

Acute 

Int. 

Acute 

Int. 

Chr. 

0.006 mg/m3 

0.0002 mg/m3 

0.001 mg/kg/day 

0.00009 mg/kg/day 

0.00006 mg/kg/day 

30 Neurol. 

30 Neurol.

100 Neurol.

100 Develop.

1000 Neurol.

Final 08/95 298-04-4 

ENDOSULFAN 

 

Oral Acute 

Int. 

Chr. 

0.007 mg/kg/day 

0.005 mg/kg/day 

0.005 mg/kg/day 

100 Neurol. 

100 Immuno. 

100 Immuno.

Draft 05/13 115-29-7 

ENDRIN 

 

Oral Int. 

Chr. 

0.002 mg/kg/day 

0.0003 mg/kg/day 

100 Neurol. 

100 Neurol.

Final 08/96 72-20-8 

ETHION 

 

Oral Acute 

Int. 

Chr. 

0.002 mg/kg/day 

0.002 mg/kg/day 

0.0004 mg/kg/day 

30 Neurol. 

30 Neurol.

150 Neurol.

Final 09/00 563-12-2 

ETHYLBENZENE 

 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Int. 

5 ppm 

2 ppm 

0.06 ppm 

0.4 mg/kg/day 

 

 

30 Neurol. 

30 Neurol.

300 Renal

 30 Hepatic

Final 11/10 100-41-4 

ETHYLENE GLYCOL 

 

 

Inh. 

Oral 

Acute 

Acute 

Int. 

2 mg/m3 

0.8 mg/kg/day 

0.8 mg/kg/day 

10 Resp. 

100 Develop.

100 Develop.

Final 11/10 107-21-1 
July 2013 ATSDR Minimal Risk Levels Page 8 of 14 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ETHYLENE OXIDE Inh. Int. 0.09 ppm 100 Renal Final 12/90 75-21-8 

FLUORANTHENE Oral Int. 0.4 mg/kg/day 300 Hepatic Final 08/95 206-44-0 

FLUORENE Oral Int. 0.4 mg/kg/day 300 Hepatic Final 08/95 86-73-7 

FLUORIDE, SODIUM Oral Chr. 0.05 mg/kg/day 3 Musculo. Final 09/03 7681-49-4 

FLUORINE Inh. Acute 0.01 ppm 10 Resp. Final 09/03 7782-41-4 

FORMALDEHYDE 

 

 

Inh. 

Oral 

Acute 

Int. 

Chr. 

Int. 

Chr. 

0.04 ppm 

0.03 ppm 

0.008 ppm 

0.3 mg/kg/day 

0.2 mg/kg/day 

9 Resp. 

30 Resp.

30 Resp.

100 Gastro.

100 Gastro.

Final 07/99 50-00-0 

FUEL OIL NO.2 Inh. Acute 0.02 mg/m3 1000 Neurol. Final 06/95 68476-30-2 

GUTHION (AZINPHOS-METHYL) Inh. 

 

 Oral 

 

Acute 

Int. 

Chr. 

Acute 

Int. 

Chr. 

0.02 mg/m3 

0.01 mg/m3 

0.01 mg/m3 

0.01 mg/kg/day 

0.003 mg/kg/day 

0.003 mg/kg/day 

30 Neurol. 

30 Neurol.

30 Neurol.

100 Neurol.

100 Neurol.

100 Neurol.

Final 09/08 86-50-0 

HEPTACHLOR Oral 

 

Acute 

Int. 

0.0006 mg/kg/day 

0.0001 mg/kg/day 

3000 Repro. 

300 Immuno.

Final 08/07 76-44-8 

HEXACHLOROBENZENE Oral 

 

Acute 

Int. 

Chr. 

0.008 mg/kg/day 

0.0001 mg/kg/day 

0.00007 mg/kg/day 

300 Develop. 

90 Repro.

300 Hepatic

Draft 06/13 118-74-1 

HEXACHLOROBUTADIENE Oral Int. 0.0002 mg/kg/day 1000 Renal Final 05/94 87-68-3 

ALPHA-HEXACHLOROCYCLOHEXANE Oral Chr. 0.008 mg/kg/day 100 Hepatic Final 09/05 319-84-6 

BETA-HEXACHLOROCYCLOHEXANE Oral 

 

Acute 

Int. 

0.05 mg/kg/day 

0.0006 mg/kg/day 

100 Neurol. 

300 Hepatic

Final 09/05 319-85-7 

GAMMA-HEXACHLOROCYCLOHEXANE Oral 

 

Acute 

Int. 

0.003 mg/kg/day 

0.00001 mg/kg/day 

300 Develop. 

1000 Immuno.

Final 09/05 58-89-9 
July 2013 ATSDR Minimal Risk Levels Page 9 of 14 

HEXACHLOROCYCLOPENTADIENE 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Inh. 

Oral 

Int. 

Chr. 

Int. 

0.01 ppm 

0.0002 ppm 

0.1 mg/kg/day 

30 Resp. 

90 Resp.

100 Renal

Final 07/99 77-47-4 

HEXACHLOROETHANE 

 

 

Inh. 

Oral 

Acute 

Int. 

Acute 

Int. 

6 ppm 

6 ppm 

1 mg/kg/day 

0.01 mg/kg/day 

30 Neurol. 

30 Neurol.

100 Hepatic

100 Hepatic

Final 09/97 67-72-1 

HEXAMETHYLENE DIISOCYANATE 

 

Inh. Int. 

Chr. 

0.00003 ppm 

0.00001 ppm 

30 Resp. 

90 Resp.

Final 10/98 822-06-0 

N-HEXANE Inh. Chr. 0.6 ppm 100 Neurol. Final 07/99 110-54-3 

HMX (CYCLOTETRAMETHYLENE 

 TETRANITRAMINE) 

Oral Acute 

Int. 

0.1 mg/kg/day 

0.05 mg/kg/day 

1000 Neurol. 

1000 Hepatic

Final 09/97 2691-41-0 

HYDRAZINE Inh. Int. 0.004 ppm 300 Hepatic Final 09/97 302-01-2 

HYDROGEN FLUORIDE Inh. Acute 0.02 ppm 30 Resp. Final 09/03 7664-39-3 

HYDROGEN SULFIDE 

 

Inh. Acute 

Int. 

0.07 ppm 

0.02 ppm 

27 Resp. 

30 Resp.

Final 07/06 7783-06-4

IODIDE 

 

Oral Acute 

Chr. 

0.01 mg/kg/day 

0.01 mg/kg/day 

1 Endocr. 

1 Endocr.

Final 10/04 7553-56-2

IONIZING RADIATION, N.O.S. 

 

Rad. Acute 

Chr. 

4 mSv 

1 mSv/yr 

3 Neurol. 

3 Other

Final 09/99 HZ1800-45-T

ISOPHORONE 

 

Oral Int. 

Chr. 

3 mg/kg/day 

0.2 mg/kg/day 

100 Other 

1000 Hepatic

Final 12/89 78-59-1

JP-4 Inh. Int. 9 mg/m3 300 Hepatic Final 06/95 50815-00-4

JP-5/JP-8 Inh. Int. 3 mg/m3 300 Hepatic Final 10/98 HZ0600-26-T

JP-7 Inh. Chr. 0.3 mg/m3 300 Hepatic Final 06/95 HZ0600-22-T

KEROSENE Inh. Int. 0.01 mg/m3 1000 Hepatic Final 06/95 8008-20-6
July 2013 ATSDR Minimal Risk Levels Page 10 of 14 

MALATHION 

 

 

 

 

Inh. 

Oral 

Acute 

Int. 

Int. 

Chr. 

0.2 mg/m3 

0.02 mg/m3 

0.02 mg/kg/day 

0.02 mg/kg/day 

 

 

100 Neurol. 

1000 Resp.

10 Neurol.

100 Neurol.

Final 09/03 121-75-5 

MANGANESE, RESPIRABLE Inh. Chr. 0.3 ug/m3 100 Neurol. Final 09/12 7439-96-5 

MERCURIC CHLORIDE 

 

Oral Acute 0.007 mg/kg/day 

Int. 0.002 mg/kg/day 

 

 

100 Renal Final 

100 Renal

03/99 7487-94-7 

MERCURY Inh. Chr. 0.0002 mg/m3 30 Neurol. Final 03/99 7439-97-6 

METHOXYCHLOR Oral Int. 0.005 mg/kg/day 1000 Repro. Draft 09/00 72-43-5 

4,4'-METHYLENEBIS(2-CHLOROANILINE) Oral Chr. 0.003 mg/kg/day 3000 Hepatic Final 05/94 101-14-4 

METHYLENE CHLORIDE 

 

 

 

Inh. 

 

Oral 

Acute 0.6 ppm 

Int. 0.3 ppm 

Chr. 0.3 ppm 

Acute 0.2 mg/kg/day 

Chr. 0.06 mg/kg/day 

100 Neurol. Final 

90 Hepatic

30 Hepatic

100 Neurol.

100 Hepatic

09/00 75-09-2 

4,4'-METHYLENEDIANILINE 

 

 Oral Acute 0.2 mg/kg/day 

Int. 0.08 mg/kg/day 

300 Hepatic Final 

100 Hepatic

10/98 101-77-9 

METHYLMERCURY Oral Chr. 0.0003 mg/kg/day 4.5 Develop. Final 03/99 22967-92-6 

1-METHYLNAPHTHALENE Oral Chr. 0.07 mg/kg/day 1000 Resp. Final 09/05 90-12-0 

2-METHYLNAPHTHALENE Oral Chr. 0.04 mg/kg/day 100 Resp. Final 09/05 91-57-6 

METHYL PARATHION 

 

Oral Int. 0.0007 mg/kg/day 

Chr. 0.0003 mg/kg/day 

 

 

300 Neurol. Final 

100 Hemato.

09/01 298-00-0 

METHYL-T-BUTYL ETHER 

 

 

Inh. 

Oral 

Acute 2 ppm 

Int. 0.7 ppm 

Chr. 0.7 ppm 

Acute 0.4 mg/kg/day 

Int. 0.3 mg/kg/day 

100 Neurol. Final 

100 Neurol.

100 Renal

100 Neurol.

300 Hepatic

08/96 1634-04-4 

MIREX Oral Chr. 0.0008 mg/kg/day 100 Hepatic Final 08/95 2385-85-5 

MONOMETHYLARSONIC ACID 

(MMA) 

Oral Int. 0.1 mg/kg/day 

Chr. 0.01 mg/kg/day 

100 Gastro. Final 

100 Renal

08/07 124-58-3 
July 2013 ATSDR Minimal Risk Levels Page 11 of 14 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

NAPHTHALENE 

 

 

Inh. 

Oral 

Chr. 

Acute 

Int. 

0.0007 ppm 

0.6 mg/kg/day 

0.6 mg/kg/day 

300 Resp. 

90 Neurol.

90 Neurol.

Final 09/05 91-20-3 

N-NITROSODI-N-PROPYLAMINE Oral Acute 0.095 mg/kg/day 100 Hepatic Final 12/89 621-64-7 

NICKEL 

 

Inh. Int. 

Chr. 

0.0002 mg/m3 

0.00009 mg/m3 

30 Resp. 

30 Resp.

Final 09/05 7440-02-0 

2,3,4,7,8-PENTACHLORODIBENZOFURAN 

 

Oral Acute 

Int. 

0.001 ug/kg/day 

0.00003 ug/kg/day 

3000 Immuno. 

3000 Hepatic

Final 05/94 57117-31-4 

PENTACHLOROPHENOL 

 

Oral Acute 

Int. 

Chr. 

0.005 mg/kg/day 

0.001 mg/kg/day 

0.001 mg/kg/day 

1000 Develop. 

1000 Repro.

1000 Endocr.

Final 09/01 87-86-5 

PERCHLORATES Oral Chr. 0.0007 mg/kg/day 10 Endocr. Final 08/08 7778-74-7 

PERMETHRIN 

 

Oral Acute 

Int. 

0.3 mg/kg/day 

0.2 mg/kg/day 

100 Neurol. 

100 Neurol.

Final 09/03 52645-53-1 

PHENOL Oral Acute 1 mg/kg/day 100 Body Wt. Final 09/08 108-95-2 

PHOSPHORUS, WHITE 

 

Inh. 

Oral 

Acute 

Int. 

0.02 mg/m3 

0.0002 mg/kg/day 

30 Resp. 

100 Repro.

Final 09/97 7723-14-0 

POLYBROMINATED BIPHENYLS (PBBs) Oral Acute 0.01 mg/kg/day 100 Endocr. Final 10/04 36355-01-8 

POLYBROMINATED DIPHENYL ETHERS 

(PBDEs), LOWER BROMINATED 

 

Inh 

Oral 

Int. 

Acute 

Int. 

0.006 mg/m3 

0.03 mg/kg/day 

0.007 mg/kg/day 

90 Endocr. 

30 Endocr. 

300 Hepatic

Final 10/04 32534-81-9 

32536-52-0 

PBDEs, DECABROMINATED Oral Int. 10 mg/kg/day 100 Develop. Final 10/04 1163-19-5 

POLYCHLORINATED BIPHENYLS (PCBs) 

(Aroclor 1254) 

Oral Int. 

Chr. 

0.03 ug/kg/day 

0.02 ug/kg/day 

300 Neurol. 

300 Immuno.

Final 11/00 11097-69-1 

PROPYLENE GLYCOL Inh. Int. 0.009 ppm 1000 Resp. Final 09/97 57-55-6 

PROPYLENE

 

GLYCOL DINITRATE Inh. Acute 

Int. 

Chr. 

0.003 ppm 

0.00004 ppm 

0.00004 ppm 

10 

1000 

1000 

Neurol. 

Hemato.

Hemato.

Final 06/95 6423-43-4 
July 2013 ATSDR Minimal Risk Levels Page 12 of 14 

RDX (Cyclonite) 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Oral Acute 

Int. 

Chr. 

0.2 mg/kg/day 

0.1 mg/kg/day 

0.1 mg/kg/day 

30 Neurol. 

30 Neurol.

30 Neurol.

Final 01/12 121-82-4 

REFRACTORY CERAMIC FIBERS Inh. Chr. 0.03 fibers/cc 30 Resp. Final 10/04 HZ0900-26-T 

SELENIUM Oral Chr. 0.005 mg/kg/day 3 Dermal Final 09/03 7782-49-2 

STRONTIUM Oral Int. 2 mg/kg/day 30 Musculo. Final 10/04 7440-24-6 

STYRENE 

 

 

Inh. 

Oral 

Acute 

Chr. 

Acute 

5 ppm 

0.2 ppm 

0.1 mg/kg/day 

10 Neurol. 

 30 Neurol.

1000 Neurol.

Final 11/10 100-42-5 

SULFUR DIOXIDE Inh. Acute 0.01 ppm 9 Resp. Final 12/98 7446-09-5 

SULFUR MUSTARD 

 

 

Inh. 

Oral 

Acute 

Int. 

Acute 

Int. 

0.0007 mg/m3 

0.00002 mg/m3 

0.5 ug/kg/day 

0.07 ug/kg/day 

30 Ocular 

30 Ocular

1000 Develop.

300 Gastro.

Final 09/03 505-60-2 

2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN Oral 

 

Acute 

Int. 

Chr. 

0.0002 ug/kg/day 

0.00002 ug/kg/day 

0.000001 ug/kg/day 

21 Immuno. 

30 Lymphor.

90 Develop.

Final 12/98 1746-01-6 

1,1,2,2-TETRACHLOROETHANE Oral Int. 0.5 mg/kg/day 100 Hepatic Final 09/08 79-34-5 

TETRACHLOROETHYLENE Inh. 

 

 Oral 

Acute 

Chr. 

Acute 

0.2 ppm 

0.04 ppm 

0.05 mg/kg/day 

10 Neurol. 

100 Neurol.

100 Develop.

Final 09/97 127-18-4 

TIN, INORGANIC Oral Int. 0.3 mg/kg/day 100 Hemato. Final 09/05 7440-31-5 

TIN, DIBUTYL-, DICHLORIDE Oral Int. 0.005 mg/kg/day 1000 Immuno. Final 09/05 683-18-1 

TIN, TRIBUTYL-, OXIDE Oral 

 

Int. 

Chr. 

0.0003 mg/kg/day 

0.0003 mg/kg/day 

100 Immuno. 

100 Immuno.

Final 09/05 56-35-9 

TITANIUM TETRACHLORIDE Inh. 

 

Int. 

Chr. 

0.01 mg/m3 

0.0001 mg/m3 

90 Resp. 

90 Resp.

Final 09/97 7550-45-0 
July 2013 ATSDR Minimal Risk Levels Page 13 of 14 

TOLUENE 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Inh. 

Oral 

Acute 

Chr. 

Acute 

Int. 

1 ppm 

0.08 ppm 

0.8 mg/kg/day 

0.02 mg/kg/day 

10 Neurol. Final 09/00 

100 Neurol.

300 Neurol.

300 Neurol.

108-88-3 

TOXAPHENE 

 

Oral Acute 

Int. 

0.05 mg/kg/day 

0.002 mg/kg/day 

100 Neurol. Draft 09/10 

100 Immuno.

8001-35-2 

TRIBUTYL PHOSPHATE 

(TnBP) 

 

Oral Acute 

Int. 

Chr. 

1.1 mg/kg/day 

0.08 mg/kg/day 

0.08 mg/kg/day 

100 Body Wt. Final 09/12 

100 Renal

100 Renal

126-73-8 

1,2,4-TRICHLOROBENZENE 

 

Oral Int. 

Chr. 

0.1 mg/kg/day 

0.1 mg/kg/day 

100 Hepatic Draft 9/10 

100 Hepatic

120-82-1 

1,1,1-TRICHLOROETHANE 

 

 

Inh. 

Oral 

Acute 

Int. 

Int. 

2 ppm 

0.7 ppm 

20 mg/kg/day 

 100 Neurol. Final 07/06 

100 Neurol.

100 Body Wt.

71-55-6 

1,1,2-TRICHLOROETHANE 

 

Oral Acute 

Int. 

0.3 mg/kg/day 

0.04 mg/kg/day 

100 Neurol. Final 12/89 

100 Hepatic

79-00-5 

TRICHLOROETHYLENE 

 

Inh. Chr. 0.0004 ppm 10 Develop. Addendum 01/13 

100 Immuno.

79-01-6 

 

 

Oral Chr. 0.0005 mg/kg/day 10 Develop.

100 Immuno.

 1000 Immuno.

1,2,3-TRICHLOROPROPANE 

 

Inh. 

Oral 

Acute 

Int. 

0.0003 ppm 

0.08 mg/kg/day 

100 Resp. Final 09/92 

100 Hepatic

96-18-4 

TRICRESYL PHOSPHATE 

(TCP) 

Oral Int. 

Chr. 

0.04 mg/kg/day 

0.02 mg/kg/day 

100 Reprod. Final 09/12 

100 Reprod.

1330-78-5 

2,4,6-TRINITROTOLUENE Oral Int. 0.0005 mg/kg/day 1000 Hepatic Final 06/95 118-96-7 

TRIS(2-BUTOXYETHYL) PHOSPHATE 

(TBEP) 

Oral Acute 

Int. 

4.8 mg/kg/day 

0.09 mg/kg/day 

100 Body Wt. Final 09/12 

100 Hepatic

78-51-3 

TRIS(2-CHLOROETHYL) PHOSPHATE 

(TCEP) 

Oral Int. 

Chr. 

0.6 mg/kg/day 

0.2 mg/kg/day 

100 Neurol. 

100 Renal

 Final 09/12 115-96-8 

TRIS(1,3-DICHLORO-2-PROPYL) 

PHOSPHATE (TDCP) 

Oral Int. 

Chr. 

0.05 mg/kg/day 

0.02 mg/kg/day 

100 Renal 

100 Renal

Final 09/12 13674-87-8 
July 2013 ATSDR Minimal Risk Levels Page 14 of 14 

URANIUM, SOLUBLE SALTS 

 

 

 Inh. 

Oral 

Int. 

Chr. 

Acute 

Int. 

0.0001 mg/m3 

0.00004 mg/m3 

0.002 mg/kg/day 

0.0002 mg/kg/day 

 

 

300 Renal 

100 Renal

100 Develop.

300 Renal

Final 02/13 7440-61-1 

URANIUM, INSOLUBLE COMPOUNDS 

 

 Inh. Int. 

Chr. 

 0.002 mg/m3 

 0.0008 mg/m3 

100 Renal 

1000 Resp.

Final 02/13 7440-61-1 

VANADIUM 

 

 

 

 

Inh. 

Oral 

Acute 0.0008 mg/m3 

Chr. 0.0001 mg/m3 

Int. 0.01 mg/kg/day 

90 Resp. 

30 Resp.

10 Hemato.

Final 09/12 7440-62-2 

VINYL ACETATE Inh. Int. 0.01 ppm 100 Resp. Final 07/92 108-05-4 

VINYL CHLORIDE 

 

 

Inh. 

Oral 

Acute 0.5 ppm 

Int. 0.03 ppm 

Chr. 0.003 mg/kg/day 

30 Develop. Final 

30 Hepatic

30 Hepatic

07/06 75-01-4 

XYLENES, MIXED 

 

 

Inh. 

Oral 

Acute 2 ppm 

Int. 0.6 ppm 

Chr. 0.05 ppm 

Acute 1 mg/kg/day 

Int. 0.4 mg/kg/day 

Chr. 0.2 mg/kg/day 

30 Neurol. Final 

90 Neurol.

300 Neurol.

100 Neurol.

1000 Neurol.

1000 Neurol.

08/07 1330-20-7 

ZINC 

 

Oral Int. 0.3 mg/kg/day 

Chr. 0.3 mg/kg/day 

3 Hemato. Final 

3 Hemato.

09/05 7440-66-6 

______________________________________________________________________________________________________________

Total number of MRLs: 401

For Duration, Acute = 1 to 14 days, Intermediate = 15 to 364 days, and Chronic = 1 year or longer.

For general information on ATSDR Minimal Risk Levels, see www.atsdr.cdc.gov/mrls.

For more information on a specific MRL, please refer to our Toxicological Profiles,

particularly Appendix A of Profiles written after 1995.

The Profiles can be found online at www.astdr.cdc.gov or ordered via cdcinfo@cdc.gov or 1-800-CDC-INFO.