U. S. ENVIRONMENTAL PROTECTION AGENCY Washington, D.C. 20460

OFFICE OF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES

Date: July

16 , 2009 PC Code : 124002 DP Barcode : D363989 and D364309

MEMORANDUM Subject: Novaluron and Novaluron Degradates (C hlorophenyl urea and C hloroaniline )

Drinking Water Assessment in Support of New Use Registration Action for Sorghum, Fruiting Vegetables (Group 8, D364309), Cucurbit Vegetables (Group 9), Low - growing Berry

Subgroup (13
- 07G), Snap and Dry Bean, and Swiss Chard. To : George Kramer, RAB 1

Dana Vogel , Branch Chief, RAB1 Health Effects Division (7509P) John Hebert, P M 07 Insecticide
- Rodenticide Branch, Product Manager 7 Registration Division (750 5P) Barbra Madden, RM 05 Risk Integration, Minor Use and Emergency Response Branch Registration Division (7505P) From: Iw ona L. Maher, Chemist, ERBI

Faruque, Khan, Ph.D., Senior Scientist, ERBI Nancy Andrews, Ph.D., Branch Chief, ERBI Environmental Fate and Effects Division (7507P) The registrant is proposing to add six new use s: sorghum, fruiting vegetables (Group 8, D364309), cucurbit vegetables (group 9), low growing berry subgroup (13
- 07G), snap and dry bean, and swiss chard (D364313) to the RimOn 0.83EC product label. Based on a review and2

anal ys is of the application information provided on the product la bel for this end
- use product , novaluron application rates proposed for these six crop groups are lower than th e highest application rates for currently registered and previously proposed , under review , uses for novaluron , on pome fruits and stone fruits , respectively
. Since the application rates are significantl y lower for the proposed uses than those for pome fruits and stone fruits, the e stimated drinking water concentrations provided in the previous drinking water ass essment dated March 10, 2009 (USEPA, D357061) and February 11, 2004 (USEPA, D285477) are applicable for the proposed uses. Table 1 lists novaluron maximum application rates for the proposed and registered crop use s based on the RimOn 0.83EC product label dated March 13, 2009 , and previously proposed , under review , stone fruits uses based on the label dated January 29, 2009
. The maximum application rates for the propose uses are 0.078 lbs a.i./A for a single application , and 0.234 lbs a.i./A for an annual application rate. These rates are four times lower than the previousl y proposed and registered uses (pome and stone fruits) for novaluron
. The label language is not explicit whether aerial and ground application are allowed for each of the uses, however , based on the use direction s provided , it was assumed that both ground and aerial applications are permitted. Table 1. Novaluron application rates for the p roposed, under review, and registered 1 uses. Crop (Subgroup) Maximum Application Rate (Lb ai/A) Maximum Number

of Applications Per Year Minimum

Interval Between Applications Application

Method Single Annual Pome Fruit 1 0.324 0.972 3 10 G, A Stone Fruit (12) 2 0.324 0.972 3 7 3 G, A Sorghum 0.078 0.234 3 7 G, A Fruiting Vegetables 0.078 0.234 3 7 G, A Cucurbit Vegetables 0.078 0.234 3 14 G, A Lo w - growing Berry Subgroup ( 13
- 07G ) 4 0.078 0.234 3 7 G, A Straw berry 0.078 0.234 3 14 G, A Snap and Dry Beans 0.078 0.23 4 3 7 G, A Swiss Chard 0.078 0.234 3 7 G, A 1

– Itshows only the highest maximum registered application rate for novaluron; i.e. pome fruits (except pears) per March 19, 2009, label
. 2

– EFED Sec 3 Chapter for stone fruits was completed in Apri l 14, 200 9 and the use is under review (petition 8E7426 )
. 3

– According to the proposed label the consequent applications to stone fruit should be made in seven to 14
- day intervals , the lowest interval was selected. 4

– In clude Bearberry, Bilberry, Lo wb ush B erry , Cloudberry, Cranberry, Li ngonberry , Muntries , and Partridgeberry G

– Gr ound applied, A

– Aerially applied Since the application rates are much lower for the proposed uses (annuall y 0.234 lb a.i./acre) than the application rate s for apples and peaches ( annually 0.972 lb a .i./acre), the estimated drinking water concentrations for apples and peaches at the maximum application rate (USEPA, 2009, D357061, and USEPA, 2004, D285477) are applicable to the proposed uses
. Based on previousl y conducted modeling o n stone and pome fruits, the acute estimated drinking water concentration (EDWC) of novaluron in surface water is 4.72 μg/l (peach via aerial application) exceeding the solu bility of novaluron (3 μg/L ) , which is expected to be an upper bound environmental concentration
. The chronic non
- cancer EDWC is not expected to exceed3

0.76 μg/L , and the cancer/chronic drinking water concentration is not expected to exceed 0.62 μg/L for use on apple via aerial application
. An estimated peak drinking water concentration of chlorophenylurea f

rom surface water sources is 4.74 μg/L , and an estimated annual average concentration is 0.89 μg/L based on novaluron’s maximum application rate of 0.32 lb ai/acre applied 3 times a season every 7 days (0 .96 lbs ai/year, stone fruit). The estimated peak drinking water concentration of chloroaniline is 11.4 μg/L and exceeding the estimated solubility of chloroaniline (10.6 μg/L) , which is expected to be the upper bound environmental concentration. The estimated annual average chloroaniline concentration is 2.6 μg/Lobtained from novaluron application rate of 0.32 lb ai/acre applied 3 times a season every 10 days (0.96 lbs ai/year, pome fruit). For the annual application rate of 0.96 lb a.i./acre (i.e., three applications of 0.32 lb a.i./acre; use on apples and peaches), SCI
- GROW novaluron predicted ground water co ncentration is 5.6 x 10 - 3 μg/Lin drinking water from shallow ground water sources. The predicted ground water con centration is 4.5 x 10
- 3 μg/L fo r chlorophenylurea and 9.0 x 10
- 3 μg/Lfor chloroaniline from novaluron’s maximum up to date application rate (0.96 lb a.i./acre ; pome and ston e fruits ). These concentrations may be considered as both the peak and annual average upper bound exposures. Table 2 provides the previously EDWCs for novaluron uses on pome and stone fruits that are recommended to be used for the human health exposure as sessment for currentl y proposed uses.
Table 2 . Estimated drinking water concentrations (EDWCs) resulting from applications of novaluron. Drinking water source (model) Use

(modeled rate) application type 1 - in - 10 year acute (ppb) 1 - in - 10 year

chronic (ppb) 30 - year average

(ppb) Novaluron Surface water (PRZM/EXAMS) PA Apples

(0.972 lbs ai/A/year) aerial application 4.59* 0.76 0.62 GA Peach (0.972 lbs ai/A/year) aerial application 4.72* 0.51 0.43 Groundwater (SCIGROW) Apples/Peaches

( 0.972 lbs ai/A/year) aerial application 0.0056 < 0.0056 < 0.0056 Chlorophenyl Urea Surface water ( FIRST ) Apples

( 0.972 lbs ai/A/year) aerial application 4.55 ≤ 0.86 ≤ 0.86 Peaches ( 0.972 lbs ai/A/year) aerial application 4.74 ≤ 0.89 ≤ 0.89 Groundwater (SCIGROW) Apples/Peaches

( 0.972 lbs ai/A/year) aerial application 0.0045 < 0.0045 < 0.0045 Chloroaniline Surface water (FIRST ) Apples/Peaches

( 0.972 lbs ai/A/year) aerial application 11.4* * ≤ 2.60 ≤ 2.604

Table 2 . Estimated drinking water concentrations (EDWCs) resulting from applications of novaluron. Drinking water source (model) Use

(modeled rate) application type 1 - in - 10 year acute (ppb) 1 - in - 10 year

chronic (ppb) 30 - year average

(ppb) Groundwater (SCIGROW) Apples/Peaches

( 0.972 lbs ai/A/year) aerial application 0.009 < 0.009 < 0.009 *T hese values exceed the measured water solubility of novaluron; i.e. 3 μg/L (3 ppb). * * This value exc eeds the estimated water solubility of chloroaniline; i.e. 10.6 μg/L (10.6 ppb). For further details regarding novaluron drinking water modeling for pome and stone fruits uses , refer to the pr evious drinking water assessments dated March 10, 2009 (USEPA , D357061 ) and February

11, 2004 (USEPA, D285477)
.