Exhibit
4.2


 


Execution
Version


 


NEITHER
THE ISSUANCE AND SALE OF THIS NOTE NOR THE SECURITIES INTO WHICH THIS NOTE IS CONVERTIBLE INTO HAVE BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED
OR ASSIGNED IN THE ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT FOR THE SECURITIES UNDER THE SECURITIES ACT OF 1933, AS
AMENDED, OR (B) AN OPINION OF COUNSEL TO THE PARENT OR THE HOLDER, IN A GENERALLY ACCEPTABLE FORM, THAT REGISTRATION IS NOT REQUIRED
UNDER SAID ACT. NOTWITHSTANDING THE FOREGOING, THE SECURITIES MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR
OTHER LOAN OR FINANCING ARRANGEMENT SECURED BY THE SECURITIES. ANY TRANSFEREE OF THIS NOTE SHOULD CAREFULLY REVIEW THE TERMS OF
THIS NOTE, INCLUDING SECTIONS 3(c)(iii) AND 18(a) HEREOF. THE PRINCIPAL AMOUNT REPRESENTED BY THIS NOTE AND, ACCORDINGLY,
THE SECURITIES ISSUABLE UPON CONVERSION HEREOF MAY BE LESS THAN THE AMOUNTS SET FORTH ON THE FACE HEREOF PURSUANT TO SECTION 3(c)(iii)
OF THIS NOTE.


 


ICAGEN-T,
INC.


 


SENIOR SECURED CONVERTIBLE NOTE


 


 


	Note
No: ICA-T – GPB - 1

        Issuance
        Date: May 15, 2017
	 	Original
    Principal Amount: U.S. $8,000,000


 


FOR
VALUE RECEIVED, Icagen-T, Inc., a Delaware corporation (“ICA-T” or the “Company”),
hereby promises to pay to the order of GPB Debt Holdings II, LLC or its registered assigns (“Holder”) the amount
set forth above as the Original Principal Amount (as reduced pursuant to the terms hereof pursuant to redemption, conversion or
otherwise, the “Principal”) when due, whether upon the Maturity Date (as defined in Section 1), acceleration,
conversion, redemption or otherwise (in each case in accordance with the terms hereof), and to pay interest (“Interest”)
on any outstanding Principal at the rate of thirteen (13%) percent per annum, as may be adjusted from time to time in accordance
with Section 2 (the “Interest Rate”) from the date set out above as the Issuance Date (the “Issuance
Date”) until the same becomes due and payable, whether upon an Interest Date (as defined below), the Maturity Date,
acceleration, conversion, redemption or otherwise (in each case in accordance with the terms hereof). This Senior Secured Convertible
Note (including all Senior Secured Convertible Notes issued in exchange, transfer or replacement hereof, this “Note”)
was issued pursuant to the Securities Purchase Agreement, dated as of May 15, 2017 (the “Subscription Date”),
by and among the Company, Icagen, Inc. a Delaware corporation and the owner of all of the issued and outstanding capital stock
of the Company (the “Parent”) and the Holder (as amended from time to time, the “Securities Purchase
Agreement”). Certain capitalized terms used herein are defined in Section 32. Capitalized terms used but
not defined herein shall have the meanings set forth in the Securities Purchase Agreement unless otherwise indicated herein as
being defined by another Transaction Document.


 






     

     

    

 


This
Note was issued with a four (4%) percent original issue discount (“OID”).


 


1.             PAYMENTS
OF PRINCIPAL; PREPAYMENT. On the Maturity Date, the Company shall pay to the Holder an amount in cash representing all then
outstanding Principal, accrued and unpaid Interest, accrued and unpaid Late Charges (as defined in Section 25(c)), on such
Principal and Interest and all other amounts due hereunder. “Maturity Date” shall be May 15, 2020; provided,
however, the Maturity Date may be extended at the sole option of the Holder in an express writing to the Company (i) in
the event that, and for so long as, an Event of Default (as defined below), shall have occurred and be continuing or any event
shall have occurred and be continuing that with the passage of time or the giving of notice (or both) and the failure to cure
would result in an Event of Default or (ii) through the date that is twenty (20) Business Days after the consummation
of a Fundamental Transaction in the event that a Fundamental Transaction is publicly announced or a Fundamental Transaction Notice
is delivered prior to the Maturity Date. Other than as expressly permitted by this Note, the Company, may not prepay any portion
of the outstanding Principal, accrued and unpaid Interest or accrued and unpaid Late Charges on Principal and Interest, if any.
Notwithstanding anything herein to the contrary, with respect to any conversion or redemption hereunder, as applicable, the Company
shall convert or redeem, as applicable, First, all accrued and unpaid Interest on any Principal and Interest hereunder,
Second, all accrued but unpaid Late Charges on any Principal and Interest hereunder, Third, all Principal outstanding
hereunder, and Fourth, all other amounts outstanding hereunder.


 


		2.	INTEREST;
                                         DEFAULT INTEREST RATE.



 


(a)          Interest
on this Note shall commence accruing on the Issuance Date at the Interest Rate computed on the basis of a 360-day year and twelve
30-day months, shall be payable in arrears on each Interest Date and shall be payable in accordance with the terms of this Note.
Interest shall be payable on each Interest Date, to the record holder of this Note on the applicable Interest Date in cash.


 


(b)         Prior
to the payment of Interest on an Interest Date, Interest on this Note shall accrue at the Interest Rate and be payable by way
of inclusion of the Interest in the Conversion Amount (as defined below), on each Conversion Date (as defined below) in accordance
with Section 3(b)(i) or upon any redemption in accordance with Section 12 or any required payment upon
any Bankruptcy Event of Default (as defined below).


 


(c)          From
and after the occurrence and during the continuation of any Event of Default, the Interest Rate shall automatically be increased
to eighteen (18%) per annum. In the event that such Event of Default is subsequently cured, and no other Event of Default then
exists, the adjustment referred to in the preceding sentence shall cease to be effective as of the calendar day immediately following
the date of such cure; provided that the Interest as calculated and unpaid at such increased rate during the continuance of such
Event of Default shall continue to apply to the extent relating to the days after the occurrence of such Event of Default through
and including the date of such cure of such Event of Default.


 






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3.             CONVERSION
OF NOTE. At any time after the Issuance Date, this Note shall be convertible into validly issued, fully paid and non-assessable
shares of Parent Common Stock (as defined in Section 32 of this Note), on the terms and conditions set forth in this Section 3.


 


(a)          Conversion
Right. Subject to the provisions of Section 3(d), at any time or times on or after the Issuance Date, the Holder
shall be entitled to convert all or any portion of the outstanding and unpaid Conversion Amount into validly issued, fully paid
and non-assessable shares of Parent Common Stock in accordance with Section 3(c), at the Conversion Rate. Parent shall
not issue any fraction of a share of Parent Common Stock upon any conversion. If the issuance would result in the issuance of
a fraction of a share of Parent Common Stock, Parent shall round such fraction of a share of Parent Common Stock up to the nearest
whole share. The Holder shall pay any and all transfer, stamp, issuance and similar taxes, costs and expenses (including, without
limitation, fees and expenses of any transfer agent of Parent (the “Transfer Agent”) and the Depository Trust
Company (“DTC”)), that may be payable with respect to the issuance and delivery of Parent Common Stock upon
conversion of any Conversion Amount.


 


(b)          Conversion
Rate. The number of shares of Parent Common Stock issuable upon conversion of any Conversion Amount (as defined below) pursuant
to Section 3(a) shall be determined by dividing (x) such Conversion Amount by (y) the Conversion Price (as
defined below) (the “Conversion Rate”).


 


(i)           “Conversion
Amount” means the sum of (A) the portion of the Principal to be converted, redeemed or otherwise with respect to
which this determination is being made, (B) all accrued and unpaid Interest with respect to such portion of such Principal,
(C) all accrued and unpaid Late Charges with respect to such portion of such Principal and such Interest, if any, and (D) all
other amounts due hereunder.


 


(ii)          “Conversion
Price” means $3.50, subject to adjustment as provided elsewhere in this Note.


 






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		(c)	Mechanics
                                         of Conversion.



  


(i)           Optional
Conversion. To convert any Conversion Amount into shares of Parent Common Stock on any date (a “Conversion Date”),
the Holder shall deliver (whether via facsimile, electronic mail or otherwise), for receipt on or prior to 11:59 p.m., New York
time, on such date, a copy of an executed notice of conversion in the form attached hereto as Exhibit I (the “Conversion
Notice”) to the Parent. If required by Section 3(c)(iii), within three (3) Trading Days, following a conversion
of this Note as aforesaid, the Holder shall surrender this Note to a nationally recognized overnight delivery service for delivery
to the Company (or an indemnification undertaking with respect to this Note in the case of its loss, theft or destruction as contemplated
by Section 19(b)). On or before the first (1st) Trading Day following the date of receipt of a Conversion Notice, the Parent
shall transmit by facsimile or electronic mail an acknowledgment of confirmation and representation as to whether such shares
of Parent Common Stock may then be resold pursuant to Rule 144 or an effective and available registration statement, in the form
attached hereto as Exhibit II, (which representation shall not include a factual analysis of whether any share caps have
been exceeded) of receipt of such Conversion Notice to the Holder and the Transfer Agent which confirmation shall constitute an
instruction to the Transfer Agent to process such Conversion Notice in accordance with the terms herein. On or before the third
(3rd) Trading Day, following the date on which the Parent has received a Conversion Notice (or such earlier date as
required pursuant to the 1934 Act or other applicable law, rule or regulation for the settlement of a trade initiated on the applicable
Conversion Date of such shares of Parent Common Stock issuable pursuant to such Conversion Notice) (the “Share Delivery
Deadline”), the Parent shall (1) provided the Transfer Agent is participating in the DTC Fast Automated Securities Transfer
Program, credit such aggregate number of shares of Parent Common Stock to which the Holder shall be entitled pursuant to such
conversion to the Holder’s or its designee’s balance account with DTC through its Deposit/Withdrawal at Custodian
system, or (2) if the Transfer Agent is not participating in the DTC Fast Automated Securities Transfer Program, upon the request
of the Holder, issue and deliver (via reputable overnight courier) to the address as specified in the Conversion Notice, a certificate,
registered in the name of the Holder or its designee, for the number of shares of Parent Common Stock to which the Holder shall
be entitled pursuant to such conversion. If this Note is physically surrendered for conversion pursuant to Section 3(c)(iii),
and the outstanding Principal of this Note is greater than the Principal portion of the Conversion Amount being converted, then
the Company shall as soon as practicable and in no event later than three (3) Business Days after receipt of this Note and at
its own expense, issue and deliver to the Holder (or its designee) a new Note (in accordance with Section 19(d)) representing
the outstanding Principal not converted. The Person or Persons entitled to receive the shares of Parent Common Stock issuable
upon a conversion of this Note shall be treated for all purposes as the record holder or holders of such shares of Parent Common
Stock on the Conversion Date. Notwithstanding anything to the contrary contained in this Note, the Securities Purchase Agreement
and/or any other Transaction Document, after the effective date of any Registration Statement (as defined in the Securities Purchase
Agreement), the Parent shall cause the Transfer Agent to deliver unlegended shares of Common Stock to the Holder (or its designee)
in connection with any sale of Registrable Securities (as defined in the Securities Purchase Agreement) with respect to which
the Holder has entered into a contract for sale, and delivered a copy of the prospectus included as part of the particular Registration
Statement to the extent applicable, and for which the Holder has not yet settled.


 






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(ii)           Parent’s
Failure to Timely Convert. If the Parent fails on or prior to a Share Delivery Deadline to issue and deliver a certificate
or credit the Holder’s or its designee’s account with DTC (as the case may be pursuant to this Section 3(c)(ii)
and/or pursuant to the Parent’s obligation pursuant to clause (II) below for the number of shares of Parent Common Stock
to which the Holder is entitled, and if on or after such Share Delivery Deadline the Holder purchases (in an open market transaction
or otherwise) shares of Parent Common Stock to deliver in satisfaction of a sale by the Holder of all or any portion of the number
of shares of Parent Common Stock issuable upon such conversion that the Holder anticipated receiving from the Parent (a “Buy-In”),
then, in addition to all other remedies available to the Holder, the Parent shall, within three (3) Trading Days after receipt
of the Holder’s request and in the Holder’s sole discretion, either, at the Holder’s option (I) pay cash to
the Holder in an amount equal to the Holder’s total purchase price (including brokerage commissions and other out-of-pocket
expenses, if any) for the shares of Parent Common Stock so purchased (including, without limitation, by any other Person in respect,
or on behalf, of the Holder) (the “Buy-In Price”), at which point the Parent’s obligation to so issue
and deliver such certificate or credit the balance account of the Holder or the Holder’s designee, as applicable, with DTC
for the number of shares of Parent Common Stock to which the Holder is entitled upon the Holder’s conversion of the applicable
Conversion Amount shall terminate, or (II) promptly (but in no event later than two (2) Trading Days following the request by
the Holder) honor its obligation to so issue and deliver to the Holder a certificate or certificates representing such shares
of Parent Common Stock or credit the balance account of such Holder or such Holder’s designee, as applicable, with DTC for
the number of shares of Parent Common Stock to which the Holder anticipated receiving from the Parent and pay cash to the Holder
in an amount equal to the excess (if any) of the Buy-In Price over the product of (x) such number of shares of Parent Common
Stock multiplied by (y) the lowest Closing Sale Price or Closing Bid Price (as the case may be) of the Parent Common Stock
on any Trading Day during the period commencing on the date of the applicable Conversion Notice and ending on the date of such
issuance and payout under this clause II (or if the Parent is then not a Trading Issuer, the Conversion Price) (the “Buy-In
Payment Amount”). Nothing herein or elsewhere shall limit the Holder’s right to pursue any other remedies available
to it hereunder, at law or in equity, including, without limitation, a decree of specific performance and/or injunctive relief
with respect to the Parent’s failure to timely deliver certificates representing shares of Parent Common Stock (or to timely
electronically deliver such shares of Parent Common Stock) upon the conversion of this Note as required pursuant to the terms
hereof. 


 






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(iii)          Registration;
Book-Entry. The Parent and the Company shall maintain a register (the “Register”) for the recordation of
the name and address of the Holder and the principal amount of the Notes (and stated interest thereon) held by the Holder (the
“Registered Notes”). The Parent and the Holder of the Note shall treat each Person whose name is recorded in
the Register as the owner of a Note for all purposes (including, without limitation, the right to receive payments of Principal,
Interest and Late Charges). A Registered Note may be assigned, transferred or sold in whole or in part by registration of such
assignment or sale on the Register but only to a Buyer Affiliate (as defined in the Securities Purchase Agreement) and/or any
other Person in accordance with Section 18. Upon its receipt of a written request to assign, transfer or sell all or part
of any Registered Note by the Holder, the Parent shall record the information contained therein in the Register and issue one
or more new Registered Notes in the same aggregate Principal amount as the Principal amount of the surrendered Registered Note
to the designated assignee or transferee pursuant to Section 19, provided that if the Parent does not so record an
assignment, transfer or sale (as the case may be) of all or part of any Registered Note within three (3) Business Days of
such a request, then the Register shall be automatically deemed updated to reflect such assignment, transfer or sale (as the case
may be). Notwithstanding anything to the contrary set forth in this Note or elsewhere, following conversion of any portion of
this Note in accordance with the terms hereof, the Holder shall not be required to physically surrender this Note to the Company
unless (A) the full Conversion Amount represented by this Note is being converted (in which event this Note shall be delivered
to the Company following conversion thereof as contemplated by Section 3(c)(i)) or (B) the Holder has provided
the Parent with prior written notice (which notice may be included in a Conversion Notice) requesting reissuance of this Note
upon physical surrender of this Note. The Holder and the Parent shall maintain records showing the Principal, Interest and Late
Charges converted and/or paid (as the case may be) and the dates of such conversions and/or payments (as the case may be) or shall
use such other method, reasonably satisfactory to the Holder and the Parent, so as not to require physical surrender of this Note
upon conversion. If the Parent does not update the Register to record such Principal, Interest and Late Charges converted and/or
paid (as the case may be) and the dates of such conversions and/or payments (as the case may be) within three (3) Business
Days of such occurrence, then the Register shall be automatically deemed updated to reflect such occurrence.


 


(iv)         Disputes.
In the event of a dispute as to the number of shares of Parent Common Stock issuable to the Holder in connection with a conversion
of this Note, the Parent shall issue to the Holder the number of shares of Parent Common Stock not in dispute and resolve such
dispute in accordance with Section 24.


 






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(d)          Limitations
on Conversions. Neither the Company nor the Parent shall effect the conversion of any portion of this Note, and the Holder
shall not have the right to convert any portion of this Note pursuant to the terms and conditions of this Note and any such conversion
shall be null and void and treated as if never made, to the extent that after giving effect to such conversion, the Holder together
with the other Attribution Parties collectively would beneficially own in excess of 4.99% (the “Maximum Percentage”)
of the shares of Parent Common Stock outstanding immediately after giving effect to such conversion such determination to be based
solely upon the Reported Outstanding Share Number (as defined below) and the number of shares disclosed to the Parent by Holder
as being beneficially owned by the Holder and the other Attribution Parties. For purposes of the foregoing sentence, the aggregate
number of shares of Parent Common Stock beneficially owned by the Holder and the other Attribution Parties shall include the number
of shares of Parent Common Stock held by the Holder and all other Attribution Parties plus the number of shares of Parent Common
Stock issuable upon conversion of this Note with respect to which the determination of such sentence is being made, but shall
exclude shares of Parent Common Stock which would be issuable upon (A) conversion of the remaining, non-converted portion
of this Note beneficially owned by the Holder or any of the other Attribution Parties and (B) exercise or conversion of the
unexercised or non-converted portion of any other securities of the Parent (including, without limitation, any convertible notes
or convertible preferred stock or warrants, including, without limitation, the Parent Note and the Parent Warrant) beneficially
owned by the Holder or any other Attribution Party subject to a limitation on conversion or exercise analogous to the limitation
contained in this Section 3(d). For purposes of this Section 3(d), beneficial ownership shall be calculated
in accordance with Section 13(d) of the 1934 Act. For purposes of determining the number of outstanding shares of Parent
Common Stock the Holder may acquire upon the conversion of this Note without exceeding the Maximum Percentage, the Holder may
rely on the number of outstanding shares of Parent Common Stock as reflected in (x) the Parent’s most recent Annual
Report on Form 10-K, Quarterly Report on Form 10-Q, Current Report on Form 8-K or other public filing with the SEC, as the case
may be, (y) a more recent public announcement by the Parent or (z) any other written notice by the Parent or the Transfer
Agent, if any, setting forth the number of shares of Parent Common Stock outstanding (the “Reported Outstanding Share
Number”). If the Parent receives a Conversion Notice from the Holder at a time when the actual number of outstanding
shares of Parent Common Stock is less than the Reported Outstanding Share Number, the Parent shall notify the Holder in writing
of the number of shares of Parent Common Stock then outstanding and, to the extent that such Conversion Notice would otherwise
cause the Holder’s beneficial ownership, as determined pursuant to this Section 3(d), to exceed the Maximum
Percentage, the Holder must (i) notify the Parent of a reduced number of shares of Parent Common Stock to be purchased pursuant
to such Conversion Notice (the number of shares by which such purchase is reduced, the “Reduction Shares”)
and (ii) as soon as reasonably practicable, the Parent shall return to the Holder any conversion price paid by the Holder
for the Reduction Shares. For any reason at any time, upon the written or oral request of the Holder, the Parent shall within
one (1) Business Day confirm orally and in writing or by electronic mail to the Holder the number of shares of Parent Common
Stock then outstanding. In any case, the number of outstanding shares of Parent Common Stock shall be determined after giving
effect to the conversion or exercise of securities of the Parent, including this Note, by the Holder and any other Attribution
Party since the date as of which the Reported Outstanding Share Number was reported. In the event that the issuance of shares
of Parent Common Stock to the Holder upon conversion of this Note results in the Holder and the other Attribution Parties being
deemed to beneficially own, in the aggregate, more than the Maximum Percentage of the number of outstanding shares of Parent Common
Stock (as determined under Section 13(d) of the 1934 Act), the number of shares so issued by which the Holder’s and
the other Attribution Parties’ aggregate beneficial ownership exceeds the Maximum Percentage (the “Excess Shares”)
shall be deemed null and void and shall be cancelled ab initio, and the Holder shall not have the power to vote or to transfer
the Excess Shares. Upon delivery of a written notice to the Parent, the Holder may from time to time increase (with such increase
not effective until the sixty-first (61st ) day after delivery of such notice) or decrease the Maximum Percentage
to any other percentage not in excess of 9.99% as specified in such notice; provided that any such increase in the Maximum Percentage
will not be effective until the sixty-first (61st ) day after such notice is delivered to the Parent. For
purposes of clarity, the shares of Parent Common Stock issuable pursuant to the terms of this Note in excess of the Maximum Percentage
shall not be deemed to be beneficially owned by the Holder for any purpose including for purposes of Section 13(d)
or Rule 16a-1(a)(1) of the 1934 Act. No prior inability to convert this Note pursuant to this paragraph shall have any effect
on the applicability of the provisions of this paragraph with respect to any subsequent determination of convertibility. The provisions
of this paragraph shall be construed and implemented in a manner otherwise than in strict conformity with the terms of this Section 3(d)
to the extent necessary to correct this paragraph (or any portion of this paragraph) which may be defective or inconsistent
with the intended beneficial ownership limitation contained in this Section 3(d) or to make changes or supplements
necessary or desirable to properly give effect to such limitation. The limitation contained in this paragraph may not be waived
and shall apply to a successor holder of this Note.


 






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		4.	EVENTS
                                         OF DEFAULT; RIGHTS UPON EVENT OF DEFAULT.



 


(a)           Event
of Default. Each of the following events shall constitute an “Event of Default” and each of the events
in clauses (iv), (v) and (vi) shall constitute a “Bankruptcy Event of Default”:


 


(i)           the
Company’s, the Parent’s and/or any of the Subsidiary’s failure to pay to the Holder any amount of Principal,
Interest, Late Charges or other amounts when and as due under this Note (including, without limitation, the Company’s, the
Parent’s and/or any Subsidiary’s failure to pay any redemption payments or amounts hereunder), any other Transaction
Document to which the Company is a party and/or any other agreement, document, certificate or other instrument delivered in connection
with the transactions contemplated hereby and thereby, except, in the case of a failure to pay Interest and Late Charges when
and as due, in which case only if such failure remains uncured for a period of at least five (5) calendar days;


 


(ii)          the
Parent fails at any time to (A) remove any restrictive legend on any certificate or any shares of Parent Common Stock issued and/or
issuable to the Holder upon conversion or exercise and/or otherwise (as the case may be) of this Note and/or any shares of Parent
Common Stock issuable hereunder as and when required by such securities, this Note and/or the Securities Purchase Agreement, unless
otherwise then prohibited by (I) applicable federal securities laws, and/or (II) any lock-up or similar written agreement to which
the Holder and any underwriter of a Qualifying PO is a party to, and any such failure remains uncured for at least three (3) consecutive
days, and (B) issue and deliver to the Holder such unlegended certificates including, but not limited to, for any shares of Parent
Common Stock issuable upon conversion and/or otherwise of this Note;


 


(iii)         the
occurrence of any default under, redemption of or acceleration prior to maturity of at least $250,000 of Indebtedness of the Company;


 


(iv)         bankruptcy,
insolvency, reorganization or liquidation proceedings or other proceedings for the relief of debtors shall be instituted by or
against the Company and, if instituted against the Company by a third party, shall not be dismissed within forty-five (45) days
of their initiation;


 


(v)          the
commencement by the Company of a voluntary case or proceeding under any applicable federal, state or foreign bankruptcy, insolvency,
reorganization or other similar law or of any other case or proceeding to be adjudicated a bankrupt or insolvent, or the consent
by it to the entry of a decree, order, judgment or other similar document in respect of the Company in an involuntary case or
proceeding under any applicable federal, state or foreign bankruptcy, insolvency, reorganization or other similar law or to the
commencement of any bankruptcy or insolvency case or proceeding against it, or the filing by it of a petition or answer or consent
seeking reorganization or relief under any applicable federal, state or foreign law, or the consent by it to the filing of such
petition or to the appointment of or taking possession by a custodian, receiver, liquidator, assignee, trustee, sequestrator or
other similar official of the Company or of any substantial part of its property, or the making by it of an assignment for the
benefit of creditors, or the execution of a composition of debts, or the occurrence of any other similar federal, state or foreign
proceeding, or the admission by it in writing of its inability to pay its debts generally as they become due, the taking of corporate
action by the Company in furtherance of any such action or the taking of any action by any Person to commence a Uniform Commercial
Code foreclosure sale or any other similar action under federal, state or foreign law;


 






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(vi)         the
entry by a court of (i) a decree, order, judgment or other similar document in respect of the Company of a voluntary or involuntary
case or proceeding under any applicable federal, state or foreign bankruptcy, insolvency, reorganization or other similar law
or (ii) a decree, order, judgment or other similar document adjudging the Company as bankrupt or insolvent, or approving
as properly filed a petition seeking liquidation, reorganization, arrangement, adjustment or composition of or in respect of the
Company under any applicable federal, state or foreign law or (iii) a decree, order, judgment or other similar document appointing
a custodian, receiver, liquidator, assignee, trustee, sequestrator or other similar official of the Company or of any substantial
part of its property, or ordering the winding up or liquidation of its affairs, and the continuance of any such decree, order,
judgment or other similar document or any such other decree, order, judgment or other similar document unstayed and in effect
for a period of sixty (60) consecutive days;


 


(vii)        a
final judgment or judgments for the payment of money aggregating in excess of $300,000 are rendered against the Company and which
judgments are not, within forty-five (45) days after the entry thereof, bonded, discharged, settled or stayed pending appeal,
or are not discharged within forty-five (45) days after the expiration of such stay; provided, however, any judgment
which is covered by insurance or an indemnity from a credit worthy party shall not be included in calculating the $300,000 amount
set forth above so long as the Company provides the Holder a written statement from such insurer or indemnity provider (which
written statement shall be reasonably satisfactory to the Holder) to the effect that such judgment is covered by insurance or
an indemnity and the Company will receive the proceeds of such insurance or indemnity within forty-five (45) days of the issuance
of such judgment;


 


(viii)       the
Company either (i) fails to pay, when due, or within any applicable grace period, any payment with respect to any Indebtedness
in excess of $250,000 due to any third party(ies) (other than, with respect to unsecured Indebtedness only, payments contested
by the Company in good faith by proper proceedings and with respect to which adequate reserves have been set aside for the payment
thereof in accordance with GAAP) or is otherwise in breach or violation of any agreement for monies owed or owing in an amount
in excess of $250,000, which breach or violation permits the other party thereto to declare a default or otherwise accelerate
amounts due thereunder, or (ii) suffers to exist any other circumstance or event that would, with or without the passage
of time or the giving of notice, result in a default or event of default under any agreement binding the Company which default
or event of default would or is likely to have a material adverse effect on the business, assets, operations (including results
thereof), liabilities, properties, condition (including financial condition) of the Company;


 


(ix)          other
than as specifically set forth in another clause of this Section 4(a), the Company breaches any material representation,
warranty, covenant or other term or condition of any Transaction Document to which it is a party (as defined in the Securities
Purchase Agreement), except, in the case of a breach of a covenant or other term or condition that is curable, only if such breach
remains uncured for a period of thirty (30) days;


 


(x)          any
breach or failure in any material respect by the Company of any provision of Section 14 of this Note;


 






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(xi)          any
material adverse effect on (i) the business, properties, assets, liabilities, operations (including results thereof), condition
(financial or otherwise) or prospects of the Company (ii) the transactions contemplated hereby or in any of the other Transaction
Documents to which the Company is a party or (iii) the authority or ability of the Company to perform any of the obligations
under any of the Transaction Documents to which the Company is a party;


 


(xii)         any
material provision of any Transaction Document to which the Company is a party (including, without limitation, the Security Documents
and the Guaranties) shall at any time for any reason (other than pursuant to the express terms thereof) cease to be valid and
binding on or enforceable against the parties thereto, or the validity or enforceability thereof shall be contested by any party
thereto, or a proceeding shall be commenced by the Company or any governmental authority having jurisdiction over any of them,
seeking to establish the invalidity or unenforceability thereof, or the Company shall deny in writing that it has any Indebtedness,
liability or obligation purported to be created under any Transaction Document (including, without limitation, the Security Documents
and the Guaranties);


 


(xiii)        any
Security Document to which the Company is a party and/or any other security document to which the Company is a party, shall at
any time for any reason fail or cease to create a separate valid and perfected and, except to the extent permitted by the terms
thereof, first priority Lien (as defined in the Securities Purchase Agreement) on any Collateral (as defined in the Security Agreement)
of the Company (“Company Collateral”) in favor of the Collateral Agent (as defined in the Securities Purchase
Agreement) or any material provision of any Security Document to which the Company is a party, shall at any time for any reason
cease to be valid and binding on or enforceable against the Company, the Parent and/or any of the Subsidiaries or the validity
or enforceability thereof shall be contested by any party thereto, or a proceeding shall be commenced by the Company, the Parent,
and/or any of the Subsidiaries or any governmental authority having jurisdiction over the Company, the Parent and/or any of the
Subsidiaries, seeking to establish the invalidity or unenforceability thereof;


 


(xiv)        any
material damage to, or loss, theft or destruction of, any Company Collateral, whether or not insured, or any strike, lockout,
labor dispute, embargo, condemnation, act of God or public enemy, or other casualty which causes, for more than fifteen (15) consecutive
calendar days, the cessation or substantial curtailment of revenue producing activities at any facility of the Company if any
such event or circumstance would have a Material Adverse Effect;


 


(xv)         if
at any time following the first date the Parent becomes a Trading Issuer the suspension from trading, or the failure of the Parent
Common Stock to be trading or listed (as applicable) on an Eligible Market for a period of five (5) consecutive Trading Days or
for more than an aggregate of ten (10) Trading Days in any 365-day period;


 






    	 	10	 



     

    

 


(xvi)        the
Parent’s (A) failure to cure a Conversion Failure by delivery of the required number of shares of Parent Common Stock
upon conversion of this Note within three (3)  Trading Days after the applicable Conversion Date or (B) notice, written
or oral, to any holder of this Note, including, without limitation, by way of public announcement or through any of its agents,
at any time, of its intention not to comply, as required, with a request for conversion of this Note into shares of Parent Common
Stock that is requested in accordance with the provisions of this Note, other than pursuant to Section 3(d),;


 


(xvii)       except
to the extent the Parent is in compliance with Section 11(b) at any time following the tenth (10th) consecutive
day that the Required Reserve Amount (as defined in Section 11(a) below) is less than the number of shares of Parent  Common
Stock that the Holder would be entitled to receive upon a conversion by the Holder of the full Conversion Amount of this Note
(without regard to any limitations on conversion set forth in this Note or otherwise);


 


(xviii)      any
event of default and/or any event that with the giving of notice or the passage of time (or both) would constitute an event of
default, under any of the Sanofi Documents (as defined in the Securities Purchase Agreement) including, but not limited to, the
S/I MSA, the S/I APA, the S/I Warranty and Reverter Deed and/or the S/I Deed of Trust (each as defined in the Securities Purchase
Agreement) and/or any other event (including, but not limited to, any sale and/or foreclosure and/or giving notice of the same
of the Property, Property Income (as both terms are defined in the S/I Deed of Trust) and/or any other items set forth in the
first paragraph of the S/I Deed of Trust used as collateral under the S/I Deed of Trust, by or for the benefit of Sanofi that
has and/or could reasonably be expected to have a Material Adverse Effect (as defined in the Securities Purchase Agreement), or
a “default” occurs (as such term is used in any provision of the S/I Deed of Trust);


 


(xix)       A
false, misleading and/or inaccurate certification (including a false or inaccurate deemed certification) by the Company, the Parent
and/or any Subsidiary as to, among other items, whether any Event of Default has occurred;


 


(xx)         the
Parent's failure for any reason immediately following the date a Registration Statement covering securities of the Parent sold
in the Qualifying PO is declared effective by the SEC or at any other time following the first date the Parent becomes a Trading
Issuer to satisfy the current public information requirement under Rule 144(c) of the 1933 Act;


 


(xxi)       the
failure of any Registration Statement (as defined in the Securities Purchase Agreement) with respect to Registrable Securities
to be declared effective by the SEC on or prior to the applicable Effectiveness Deadline (as defined in the Securities Purchase
Agreement) unless at such time counsel to the Company provides a legal opinion to the Holder and the Transfer Agent that (i) all
Registrable Securities can be sold under Rule 144 without restriction, and (ii) at each time the Holder seeks to sell any such
Registrable Securities such counsel provides a legal opinion to the Buyer and the Transfer Agent removing all restrictive and
other legends on such Registrable Securities no later than the Share Delivery Date;


 






    	 	11	 



     

    

 


(xxii)       while
any applicable Registration Statement is required to be maintained effective pursuant to the terms of the Securities Purchase
Agreement, the effectiveness of the applicable Registration Statement lapses for any reason (including, without limitation, the
issuance of a stop order) or such Registration Statement (or the prospectus contained therein) is unavailable to any holder of
Registrable Securities (as defined in the Securities Purchase Agreement) for sale of all of such holder’s Registrable Securities
registered under such Registration Statement in accordance with the terms of the Securities Purchase Agreement, and such lapse
or unavailability continues for a period of ten (10) consecutive business days or for more than an aggregate of ten (10) days
in any 365-day period;


 


(xxiii)      any
Controlled Account Agreement (as defined in the Security Agreement) of the Company shall for any reason fail or cease to create
a separate valid and perfected and, except to the extent permitted by the terms hereof or thereof, first priority Lien on the
Collateral (as defined below) in favor of the Holder and/or the Collateral Agent or any material provision of any Controlled Account
Agreement of the Company shall at any time for any reason cease to be valid and binding on or enforceable against ICA-T or the
validity or enforceability thereof shall be contested by any party thereto, or a proceeding shall be commenced by ICA-T or any
Governmental Entity (as defined in the Securities Purchase Agreement) having jurisdiction over ICA-T, seeking to establish the
invalidity or unenforceability thereof.


 


(b)          Notice
of an Event of Default; Redemption Right. Upon the occurrence of an Event of Default, the Company and the Parent shall within
one (1) Business Day of such Event of Default deliver a mutual written notice thereof via facsimile or electronic mail and
overnight courier (with next day delivery specified) (an “Event of Default Notice”) to the Holder. At any time
after the earlier of the Holder’s receipt of an Event of Default Notice and the Holder becoming aware of an Event of Default
(such earlier date, the “Event of Default Right Commencement Date”) and ending (such ending date, the “Event
of Default Right Expiration Date”, and each such period, an “Event of Default Redemption Right Period”)
on the tenth (10th) Trading Day after the later of (x) the date such Event of Default is cured and (y) the Holder’s
receipt of an Event of Default Notice that includes (I) a reasonable description of the applicable Event of Default, (II) a certification
as to whether, in the opinion of the Company and the Parent, such Event of Default is capable of being cured and, if applicable,
a reasonable description of any existing plans of the Company and/or the Parent to cure such Event of Default and (III) a certification
as to the date the Event of Default occurred and, if cured on or prior to the date of such Event of Default Notice, the applicable
Event of Default Right Expiration Date, the Holder may require the Company and/or the Parent to redeem all or any portion of this
Note by delivering written notice thereof (the “Event of Default Redemption Notice”) to the Company and/or
the Parent, which Event of Default Redemption Notice shall indicate the portion of this Note the Holder is electing to redeem.
Each portion of this Note subject to redemption by the Company and/or the Parent pursuant to this Section 4(b) shall
be redeemed by the Company and/or the Parent at a price in cash equal to the product of (A) the Conversion Amount being
redeemed multiplied by (B) (i) 116% if the applicable Event of Default Redemption Price is paid in full to the Holder on a date
prior to May 15, 2018, (ii) 117% if the Event of Default Redemption Price is paid in full to the Holder after May 15, 2018 but
prior to May 15, 2019 and (iii) 118% if the Event of Default Redemption Price is paid in full to the Holder after May 15, 2019
but on or prior to the Maturity Date (the “Event of Default Redemption Price”). Redemptions required by this
Section 4(b) shall be made in accordance with the provisions of Section 12. To the extent redemptions
required by this Section 4(b) are deemed or determined by a court of competent jurisdiction to be prepayments of this
Note by the Company and/or the Parent, such redemptions shall be deemed to be voluntary prepayments. Notwithstanding anything
to the contrary in this Section 4, but subject to Section 3(d), until the Event of Default Redemption Price
(together with any Late Charges thereon) is paid in full to the Holder as provided in this Note, the Conversion Amount submitted
for redemption under this Section 4(b) (together with Late Charges thereon) may be converted in whole or in part by the
Holder into shares of Parent Common Stock pursuant to Section 3 of this Note. In the event of the Company’s and/or
the Parent’s redemption of any portion of this Note under this Section 4(b), the Holder’s damages would
be uncertain and difficult to estimate because of the parties’ inability to predict future interest rates and the uncertainty
of the availability of a suitable substitute investment opportunity for the Holder. Accordingly, any redemption premium due under
this Section 4(b) is intended by the parties to be, and shall be deemed, a reasonable estimate of the Holder’s
actual loss of its investment opportunity and not as a penalty. Any redemption upon an Event of Default shall not constitute an
election of remedies by the Holder, and all other rights and remedies of the Holder shall be preserved.


 






    	 	12	 



     

    

 


(c)          Mandatory
Redemption upon Bankruptcy Event of Default. Notwithstanding anything to the contrary herein, and notwithstanding any conversion
that is then required or in process, upon any Bankruptcy Event of Default, whether occurring prior to or following the Maturity
Date, the Company shall immediately pay to the Holder an amount in cash representing the Event of Default Redemption Price (together
with Late Charges thereon) in addition to any and all other amounts due hereunder, without the requirement for any notice or demand
or other action by the Holder or any other person or entity, provided that the Holder may, in its sole discretion, waive such
right to receive payment upon a Bankruptcy Event of Default, in whole or in part, and any such waiver shall not affect any other
rights of the Holder hereunder, including any other rights in respect of such Bankruptcy Event of Default, any right to conversion
and any right to payment of the Event of Default Redemption Price or any other Redemption Price, as applicable.


  


5.             RIGHTS
UPON FUNDAMENTAL TRANSACTION.


 


(a)          Assumption.
Neither the Company nor the Parent shall not enter into or be party to a Fundamental Transaction unless (i) the Successor Entity
assumes in writing all of the obligations of the Company, the Parent and each Subsidiary under this Note and the other Transaction
Documents in accordance with the provisions of this Section 5(a) pursuant to written agreements in form and substance
reasonably satisfactory to the Holder and approved by the Holder prior to such Fundamental Transaction, including agreements to
deliver to the Holder in exchange for this Note and securities of the Successor Entity evidenced by a written instrument substantially
similar in form and substance to this Note (which, for the avoidance of doubt, shall not include any terms or conditions less
favorable to the Holder of this Note in any material respect than the terms and conditions set forth in this Note as of such date
of determination), including, without limitation, having principal amounts, interest rates and late charges equal to the payment
rights and amounts, principal amounts then outstanding, the interest rates and Late Charges of this Note as well as having the
conversion rights, redemption rights, rankings, Events of Default the same as in this Note and satisfactory to the Holder and,
(ii) the Successor Entity (including its Parent Entity), is a Trading Issuer whose common stock is registered under Section
12 of the 1934 Act and is quoted and/or listed for trading on a Qualifying Market. Upon the occurrence of any Fundamental
Transaction, the Successor Entity shall succeed to, and be substituted for (so that from and after the date of such Fundamental
Transaction, the provisions of this Note and the other Transaction Documents referring to the “Company” and the “Parent”
shall refer instead to the Successor Entity), and may exercise every right and power of the Company and the Parent and shall assume
all of the obligations of the Company and the Parent under this Note and the other Transaction Documents, with the same effect
as if the Successor Entity (including its Parent Entity), had been named the Company and the Parent herein and in the other Transaction
Documents. Upon consummation of a Fundamental Transaction, the Successor Entity shall deliver to the Holder confirmation that
there shall be issued upon conversion of this Note at any time after the consummation of such Fundamental Transaction, in lieu
of the shares of Parent Common Stock (or other securities, cash, assets or other property (except such items still issuable under
Section 6 and Section 16, which shall continue to be receivable thereafter) issuable upon the conversion of this
Note prior to such Fundamental Transaction, such shares of publicly traded common stock (or their equivalent) of the Successor
Entity (including its Parent Entity) which the Holder would have been entitled to receive upon the happening of such Fundamental
Transaction had this Note been converted immediately prior to such Fundamental Transaction (without regard to any limitations
on the conversion of this Note), as adjusted in accordance with the provisions of this Note. The provisions of this Section 5(a)
shall apply similarly and equally to successive Fundamental Transactions and shall be applied without regard to any limitations
on the conversion of this Note.


 






    	 	13	 



     

    

 


(b)           Notice
of a Fundamental Transaction; Redemption Right. No sooner than twenty (20) Trading Days nor later than ten
(10) Trading Days prior to the consummation of a Fundamental Transaction, but not prior to the public announcement of
such Fundamental Transaction, the Company and the Parent shall deliver a mutually executed written notice thereof via
facsimile or electronic mail and overnight courier to the Holder (a “Fundamental Transaction Notice”). At
any time during the period beginning after the Holder’s receipt of a Fundamental Transaction Notice or the Holder
becoming aware of a Fundamental Transaction if a Fundamental Transaction Notice is not delivered to the Holder in accordance
with the immediately preceding sentence (as applicable) and ending on the later of twenty (20) Trading Days after
(i) consummation of such Fundamental Transaction and (ii) the date of receipt of such Fundamental Transaction
Notice, the Holder may require the Company to redeem all or any portion of this Note by delivering written notice thereof
(“Fundamental Transaction Redemption Notice”) to the Company and the Parent, which Fundamental Transaction
Redemption Notice shall indicate the Conversion Amount the Holder is electing to redeem. The portion of this Note subject to
redemption pursuant to this Section 5(b) shall be redeemed by the Company in cash at a price equal to the
product of (A) the Conversion Amount being redeemed, and (B) (1) 101% if the Fundamental Transaction Redemption Price
(as defined below) is paid in full to the Holder on a date prior to May 15, 2018, (2) 102% if the Fundamental
Transaction Redemption Price is paid in full to the Holder on or after May 15, 2018 but prior to May 15, 2019, and (3) 103%
if the Fundamental Transaction Price is paid in full to the Holder on a date following May 15, 2019 on or prior to the
Maturity Date (the “Fundamental Transaction Redemption Price”). Redemptions required by this Section 5(b)
shall be made in accordance with the provisions of Section 12 and shall have priority to payments to stockholders
in connection with such Fundamental Transaction. To the extent redemptions required by this Section 5(b) are
deemed or determined by a court of competent jurisdiction to be prepayments of this Note by the Company, such redemptions
shall be deemed to be voluntary prepayments. Notwithstanding anything to the contrary in this Section 5(b), but
subject to Section 3(d), until the Fundamental Transaction Redemption Price (together with any Late Charges
thereon) is paid in full, the Fundamental Transaction Redemption Price (together with any Late Charges thereon) may be
converted, in whole or in part, by the Holder into Parent Common Stock pursuant to Section 3. In the event of the
Company’s redemption of any portion of this Note under this Section 5(b), the Holder’s damages would
be uncertain and difficult to estimate because of the parties’ inability to predict future interest rates and the
uncertainty of the availability of a suitable substitute investment opportunity for the Holder. Accordingly, any
redemption premium due under this Section 5(b) is intended by the parties to be, and shall be deemed, a
reasonable estimate of the Holder’s actual loss of its investment opportunity and not as a penalty.


 


6.             RIGHTS
UPON ISSUANCE OF PURCHASE RIGHTS AND OTHER CORPORATE EVENTS.


 


(a)           Purchase
Rights. In addition to any adjustments pursuant to Section 7 below, elsewhere in this Agreement and/or in any
other Transaction Document, if at any time the Parent grants, issues or sells any Common Stock Equivalents, Options, Convertible
Securities or rights to purchase stock, warrants, securities or other property pro rata to all or substantially all of the record
holders of any class of Parent Common Stock (the “Purchase Rights”), then the Holder will be entitled to acquire,
upon the terms applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder
had held the number of shares of Parent Common Stock acquirable upon complete conversion of this Note (without taking into account
any limitations or restrictions on the convertibility of this Note and assuming for such purpose that the Note was converted at
the Conversion Price as of the applicable record date) immediately prior to the date on which a record is taken for the grant,
issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which the record holders of shares of
Parent Common Stock are to be determined for the grant, issue or sale of such Purchase Rights; provided , however,
that to the extent that the Holder’s right to participate in any such Purchase Right would result in the Holder and the
other Attribution Parties exceeding the Maximum Percentage, then the Holder shall not be entitled to participate in such Purchase
Right to the extent of the Maximum Percentage (and shall not be entitled to beneficial ownership of such shares of Parent Common
Stock as a result of such Purchase Right (and beneficial ownership) to the extent of any such excess) and such Purchase Right
to such extent shall be held in abeyance (and, if such Purchase Right has an expiration date, maturity date or other similar provision,
such term shall be extended by such number of days held in abeyance, if applicable) for the benefit of the Holder until such time
or times, if ever, as its right thereto would not result in the Holder and the other Attribution Parties exceeding the Maximum
Percentage, at which time or times the Holder shall be granted such right (and any Purchase Right granted, issued or sold on such
initial Purchase Right or on any subsequent Purchase Right held similarly in abeyance (and, if such Purchase Right has an expiration
date, maturity date or other similar provision, such term shall be extended by such number of days held in abeyance, if applicable))
to the same extent as if there had been no such limitation).


 






    	 	14	 



     

    

 


(b)           Other
Corporate Events. In addition to and not in substitution for any other rights in this Note and/or in any other Transaction
Document, prior to the consummation of any Fundamental Transaction pursuant to which holders of shares of Parent Common Stock
are entitled to receive securities or other assets with respect to or in exchange for shares of Parent Common Stock (a “Corporate
Event”), the Company and the Parent shall make appropriate provision to ensure that the Holder will thereafter have
the right to receive upon a conversion of this Note, at the Holder’s option (i) in addition to the shares of Parent
Common Stock receivable upon such conversion, such securities or other assets to which the Holder would have been entitled with
respect to such shares of Parent Common Stock had such shares of Parent Common Stock been held by the Holder upon the consummation
of such Corporate Event (without taking into account any limitations or restrictions on the convertibility of this Note) or (ii) in
lieu of the shares of Parent Common Stock otherwise receivable upon such conversion, such securities or other assets received
by the holders of shares of Parent Common Stock in connection with the consummation of such Corporate Event in such amounts as
the Holder would have been entitled to receive had this Note initially been issued with conversion rights for the form of such
consideration (as opposed to shares of Parent Common Stock) at a conversion rate for such consideration commensurate with the
Conversion Rate. Provision made pursuant to the preceding sentence shall be in a form and substance satisfactory to the Holder.
The provisions of this Section 6 shall apply similarly and equally to successive Corporate Events and shall be applied
without regard to any limitations on the conversion or redemption of this Note.


 


	 	7.	 RIGHTS UPON ISSUANCE OF OTHER SECURITIES PRIOR
TO AND FOLLOWING A QUALIFIED IPO.




 


(a)          Adjustment
of Conversion Price upon Subdivision or Combination of Parent Common Stock. In addition to any other rights of the Holder
under this Note and/or any other Transaction Document and without limiting any provisions of Sections 5, 6, 7 and 16 hereof,
if the Parent at any time on or after the Subscription Date subdivides (by any stock split, stock dividend, stock combination,
recapitalization or other similar transaction) one or more classes of its outstanding shares of Parent Common Stock into a greater
number of shares, the Conversion Price in effect immediately prior to such subdivision will be proportionately reduced. Without
limiting any provisions of Sections 5, 6 and 16.1(f), the Parent at any time on or after the Subscription Date combines
(by any stock split, stock dividend, stock combination, recapitalization or other similar transaction) one or more classes of
its outstanding shares of Parent Common Stock into a smaller number of shares, the Conversion Price in effect immediately prior
to such combination will be proportionately increased. Any adjustment pursuant to this Section 7(a) shall become effective
immediately after the effective date of such subdivision or combination. If any event requiring an adjustment under this Section
7(a) occurs during the period that a Conversion Price is calculated hereunder, then the calculation of such Conversion Price
shall be adjusted appropriately to reflect such event.


 






    	 	15	 



     

    

 


(b)          Issuance
of Securities Below the Conversion Price Prior to the Closing Date of a Qualifying PO.  In addition to and not in limitation
of any other rights of the Holder under this Note including, but not limited to, Section 7 and/or any other Transaction
Document, if, at any time while this Note is outstanding and whenever on or after the Subscription Date but prior to the closing
date of a Qualifying PO (as defined below), the Company, the Parent and/or any Subsidiary in any manner sells or grants any option
to purchase, issues or sells or grants any right to reprice, and/or otherwise sells, disposes of and/or issues any shares of Parent
Common Stock or Common Stock Equivalents (as defined below) (including upon conversion, exercise or otherwise) entitling any Person
to acquire shares of Parent Common Stock at a price per share of Parent Common Stock that is lower than the then Conversion Price
(such lower price, the “New Issuance Price” and each such issuance, a “Dilutive Issuance”
and collectively, “Dilutive Issuances”), (if the holder of shares of Parent Common Stock or Common Stock Equivalents
so issued and/or any holder of Parent Common Stock and/or Common Stock Equivalents as of the Subscription Date or issued subsequent
thereto, shall at any time, whether by amendment, supplement, operation of purchase price adjustments, reset provisions, floating
conversion, exercise or exchange prices or otherwise be entitled under the terms of any such instruments to receive shares of
Parent Common Stock at a price per share that is lower than the Conversion Price, such issuance shall be deemed to have occurred
for less than the Conversion Price on such date of the Dilutive Issuance), then the then Conversion Price shall be reduced to
equal the New Issuance Price.  For purposes of clarification, if the Company, the Parent and/or any Subsidiary issues, sells
and/or otherwise disposes of any shares of Parent Common Stock at a price less than the then Conversion Price, the then Conversion
Price shall immediately be reduced to the New Issuance Price on the date of such Dilutive Issuance. All adjustments provided for
in this Section 7(b) shall be made whenever any such Parent Common Stock or Common Stock Equivalents are issued. Notwithstanding
anything to the contrary in the foregoing, if a Dilutive Issuance consists of the issuance and/or sale of both Parent Common Stock
and Common Stock Equivalents or two or more Common Stock Equivalents as units (each, a “Share and/or a CSE Issuance”),
in determining the value of the component parts of the unit issued and/or sold in a Share and/or a CSE Issuance no value will
be attributed to Common Stock Equivalents and the New Issuance Price as a result thereof will be the lowest of (i) the lowest
purchase price per unit, (ii) the lowest conversion, exercise and/or exchange price to acquire one (1) share of Parent Common
Stock of any Common Stock Equivalent included in a unit if a unit also includes shares of Parent Common Stock, and (iii) if no
shares of Parent Common Stock are included in a unit, the lowest exercise, conversion and/or exchange price to acquire one (1)
share of Parent Common Stock of the Common Stock Equivalents comprising a unit, such lowest price of (i)-(iii) shall be the “Lowest
Price;” provided, however, a Dilutive Issuance and a resulting New Issuance Price relating to a Share
and/or a CSE Issuance shall only occur if the Lowest Price relating to a Share and/or a CSE Issuance is lower than the then Conversion
Price. Notwithstanding the foregoing, no adjustment will be made under this Section 7(b) in respect of an Exempt Issuance.
  The Company and the Parent shall notify the Holder in writing, no later than the first Trading Day following the issuance
of any Parent Common Stock or Common Stock Equivalents subject to this Section 7(b), indicating therein the applicable
Lowest Price, issuance price, reset price, exchange price, conversion price and other pricing terms (such notice, the “Dilutive
Issuance Notice”). For purposes of clarification, whether or not the Parent provides a Dilutive Issuance Notice upon
the occurrence of any Dilutive Issuance, the Holder is entitled to receive a number of shares of Parent Common Stock based upon
the New Issuance Price on or after the date of such Dilutive Issuance, regardless of whether the Holder accurately refers to the
New Issuance Price in any Notice of Conversion. For purposes hereof, the term “Common Stock Equivalents” means
any securities (as defined under the 1933 Act) including, but not limited to, any Options and/or Convertible Securities of the
Company, the Parent and/or any Subsidiaries which would entitle the Holder thereof to acquire at any time shares of Parent Common
Stock, including, without limitation, any debt, preferred stock, right, option, warrant or other instrument that is at any time
convertible into or exercisable or exchangeable for, or otherwise entitles the Holder thereof to receive, shares of Parent Common
Stock. If the Parent, the Company and/or any Subsidiary enters into a Variable Rate Transaction (as
defined in the Securities Purchase Agreement) despite the prohibition set forth in the Securities Purchase Agreement, the Parent
shall be deemed to have issued shares of Parent Common Stock or Common Stock Equivalents at the lowest possible price at which
such securities may be converted, exchanged and/or exercised under the terms of such Variable Rate Transaction.


 






    	 	16	 



     

    

 


(c)          Issuance
of Securities Below the Conversion Price Following the First Trading Day Following the Closing of a Qualifying PO.  In
addition to and not in limitation of any other rights of the Holder under this Note including, but not limited to, Section
7 and/or any other Transaction Document, if, at any time while this Note is outstanding and whenever on or after the first
Trading Day following the closing date of a Qualifying PO, the Company, the Parent and/or any Subsidiary in any manner sells or
grants any option to purchase, issues or sells or grants any right to reprice, and/or otherwise sells, disposes of and/or issues
any shares of Parent Common Stock or Common Stock Equivalents entitling any Person to acquire shares of Parent Common Stock at
a price per share of Parent Common Stock that is lower than the then Conversion Price (such lower price, the “Post-QPO
New Issuance Price” and each such issuance, a “Post-QPO Dilutive Issuance” and collectively, “Post-QPO
Dilutive Issuances”), then immediately after such Post-QPO Dilutive Issuance, the then Conversion Price shall be automatically
reduced to an amount determined by multiplying the then Conversion Price by a fraction of which (i) the numerator shall be the
sum of (A) the number of shares of Parent Common Stock issued and outstanding immediately prior to such Post-QPO Dilutive
Issuance (assuming all then issued and outstanding Common Stock Equivalents are exercised, exchanged and/or converted (as the
case may be) in accordance with the terms, without giving effect to any limitations on conversions, exchanges and/or exercise
in any such Common Stock Equivalents), plus (B) the number of shares of Parent Common Stock which the aggregate consideration
received by the Parent for such additional shares of Parent Common Stock would purchase at the then Conversion Price (without
giving effect to any limitations on conversions, exchanges and/or exercises in any outstanding Common Stock Equivalents), and
(ii) the denominator of which shall be the number of shares of Parent Common Stock issued and outstanding immediately after
and including such Post-QPO Dilutive Issuance (assuming all then issued and outstanding Common Stock Equivalents were exercised,
executed and/or converted (as the case may be) in accordance with the terms, without giving effect to any limitations on conversions,
exchanges and/or exercise in any such Common Stock Equivalents, including this Note, the Parent Note and the Parent Warrant).
For purposes of clarification, if the Company, the Parent and/or any Subsidiary issues, sells and/or otherwise disposes of any
shares of Parent Common Stock at a price less than the then Conversion Price, the then Conversion Price shall immediately be reduced
to the Post-QPO New Issuance Price on the date of such Post-QPO Dilutive Issuance as determined above. All adjustments provided
for in this Section 7(c) shall be made whenever any such Parent Common Stock or Common Stock Equivalents are issued. Notwithstanding
the foregoing, if a Dilutive Issuance results from a Share and/or a CSE Issuance no value will be attributed to Common Stock Equivalents
and the New Issuance Price as a result thereof will be the Lowest Price; provided, however, a Dilutive Issuance
and a resulting New Issuance Price relating to a Share and/or a CSE Issuance shall only occur if the Lowest Price relating to
a Share and/or a CSE Issuance is lower than the then Conversion Price. Notwithstanding the foregoing, no adjustment will be made
under this Section 7(b) in respect of an Exempt Issuance.  The Company and the Parent shall provide to the Holder
a Dilutive Issuance Notice no later than the first Trading Day following the issuance of any Parent Common Stock or Common Stock
Equivalents subject to this Section 7(c). For purposes of clarification, whether or not the Parent provides a Dilutive
Issuance Notice upon the occurrence of any Post-QPO Dilutive Issuance, the Holder is entitled to receive a number of shares of
Parent Common Stock based upon the Post-QPO New Issuance Price on or after the date of such Post-QPO Dilutive Issuance, regardless
of whether the Holder accurately refers to the Post-QPO New Issuance Price in any Notice of Conversion. If
the Parent, the Company and/or any Subsidiary enters into a Variable Rate Transaction despite the prohibition set forth in the
Securities Purchase Agreement, the Parent shall be deemed to have issued shares of Parent Common Stock or Common Stock Equivalents
at the lowest possible price at which such securities may be converted, exchanged and/or exercised under the terms of such Variable
Rate Transaction.


 


(d)          Record
Date. If the Parent takes a record of the holders of shares of Parent Common Stock for the purpose of entitling them (A) to
receive a dividend or other distribution payable in shares of Parent Common Stock and/or Common Stock Equivalents, or (B) to
subscribe for or purchase shares of Parent Common Stock and/or Common Stock Equivalents, then such record date will be deemed
to be the date of the issuance or sale of the shares of Parent Common Stock deemed to have been issued or sold upon the declaration
of such dividend or the making of such other distribution or the date of the granting of such right of subscription or purchase
(as the case may be).


 






    	 	17	 



     

    

 


(e)           Calculations.
All calculations under this Section 7 shall be made by rounding to the nearest cent or the nearest 1/100th of
a share, as applicable. The number of shares of Parent Common Stock outstanding at any given time shall not include shares owned
or held by or for the account of the Company, and the disposition of any such shares shall be considered an issue or sale of Parent
Common Stock.


 


(f)           Voluntary
Adjustability by the Parent. The Parent may at any time which this Note is outstanding, reduce the then Conversion Price to
any amount and for any period of time decided appropriate by the Board of Directors.


 


8.           
CERTAIN RESET RIGHTS UPON A QUALIFYING PO.  If on or after the Subscription Date, the Company consummates a Qualifying
PO, and on the closing date of such Qualifying PO, the then Conversion Price is greater than the Qualifying PO Per Share Sale
Price (as defined below), then the Conversion Price shall automatically and without any action by the Company or otherwise, be
reset to the Qualifying PO Per Share Sale Price.  A “Qualifying PO Per Share Sale Price” shall be
as applicable (i) the gross price a share of Parent Common Stock is sold to the public in the Qualifying PO if only shares of
Parent Common Stock are sold to the public in such Qualifying PO, (ii) the gross price a unit consisting of shares of Parent Common
Stock and Common Stock Equivalents is sold to the public in the Qualifying PO, or (iii) the sum of the gross price that (a) one
(1) share of Parent Common Stock, and (b) a Common Stock Equivalent is sold to each purchaser in a Qualifying PO.


 


9.             REDEMPTIONS
AT THE COMPANY’S ELECTION. Subject to compliance with all of the provisions of this Section 9, at any time after
the Issuance Date, the Company shall have the right to redeem all or a portion of the Conversion Amount then outstanding (the
“Company Optional Redemption Amount”) on the Company Optional Redemption Date (as defined below) (a “Company
Optional Redemption”).  So long as no Event of Default has occurred and is continuing, the portion of this Note
subject to redemption pursuant to this Section 9 shall be redeemed by the Company in cash at a price (the “Company
Optional Redemption Price”) equal to (i) if the Company’s Optional Redemption Price is paid in full to the Holder
on a date prior to May 15, 2018, 101% of the Conversion Amount being redeemed, (ii) if the Company’s Optional Redemption
Price is paid in full to the Holder on a date following May 15, 2018 but prior to May 15, 2019, 102% of the Conversion Amount
being redeemed, and (iii) the Company’s Optional Redemption Price is paid in full to the Holder after May 15, 2019 but prior
to the Maturity Date, 103% of the Conversion Amount being redeemed; provided, however, that provided the Company
has complied with its obligations under Section 4(b) including the timely delivery of an Event of Default Notice, and if
an Event of Default has occurred and is continuing, then on the Company Optional Redemption Date, the Company shall have the right
to redeem all or a portion of the Conversion Amount outstanding by the Event of Default Redemption Price in cash on the Company
Optional Redemption Date, provided the Company follows all of the provisions set forth in this Section 9. This provision
in no way shall limit the right and remedies provided to the Holder pursuant to any provision of this Note and/or elsewhere including,
but not limited to, Section 4 or this Section 9 of this Note.  The Company may exercise its right to require
redemption under this Section 9 by delivering a written notice thereof by facsimile or electronic mail and overnight courier
to the Holder, which notice shall include the signature from the Parent acknowledging such redemption and the Holder’s conversion
and related rights hereunder for the purpose of acknowledging and being aware of Holder’s conversion rights hereunder (the
“Company Optional Redemption Notice” and the date the Holder receives such notice is referred to as the “Company
Optional Redemption Notice Date”).  The Company may not deliver a Company Optional Redemption Notice hereunder
unless the aggregate Conversion Amount being redeemed pursuant to this Section 9 is at least Five Hundred Thousand Dollars
($500,000), and such Company Optional Redemption Notice shall be irrevocable.  The Company Optional Redemption Notice shall
(x) state the date on which the Company Optional Redemption shall occur (the “Company Optional Redemption Date”)
which date shall not be less than twenty (20) Trading Days nor more than thirty (30) Trading Days following the Company Optional
Redemption Notice Date, (y) certify that no Event of Default has occurred or is continuing and/or with the giving of notice or
the passage of time could occur (or with respect to a Permitted Company EOD Redemption Exception, the date the Event of Default
commenced that such Event of Default has been continuing through the date of the Company Optional Redemption Notice Date, and
(z) state the aggregate Conversion Amount of this Note being redeemed in such Company Optional Redemption from the Holder on the
Company Optional Redemption Date.  Redemptions made pursuant to this Section 9 shall be made in accordance with
Section 12. To the extent redemptions required by this Section 9(a) are deemed or determined by a court of
competent jurisdiction to be prepayments of this Note by the Company, such redemptions shall be deemed to be voluntary prepayments.
Notwithstanding anything herein to the contrary, but subject to Section 3(d), at any time prior to the date the applicable
Company Optional Redemption Price is paid in full (together with Late Charges, if any are owed, thereon), such applicable Company
Optional Redemption Amount (together with Late Charges, if any are owed, thereon), may be converted, in whole or in part by the
Holder into shares of Parent Common Stock pursuant to Section 3. The parties agree that in the event of the Company’s
redemption of any portion of this Note under this Section 9, the Holder’s damages would be uncertain and difficult
to estimate because of the parties’ inability to predict future interest rates and the uncertainty of the availability of
a suitable substitute investment opportunity for the Holder. Accordingly, any redemption premium due under this Section 9
is intended by the parties to be, and shall be deemed, a reasonable estimate of the Holder’s actual loss of its investment
opportunity and not as a penalty. For the avoidance of doubt and notwithstanding anything to the contrary provided herein or elsewhere,
without the express written consent of the Holder, the Company shall have no right to effect a Company Optional Redemption if
at any time commencing on the Company’s Optional Redemption Notice Date and terminating on the Company’s Optional
Redemption Date, any Event of Default has occurred and continuing (and/or with the giving of notice or the passage of time could
occur as a result of the applicable Company Optional Redemption, but any Event of Default shall have no effect upon the Holder’s
right to convert this Note in its discretion.


 






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10.           NONCIRCUMVENTION.
The Company and the Parent hereby each covenant and agree that neither by amendment of its respective Certificate of Incorporation
(as defined in the Securities Purchase Agreement), Bylaws (as defined in the Securities Purchase Agreement) or through any reorganization,
transfer of assets, consolidation, merger, scheme of arrangement, dissolution, issue or sale of securities, or any other voluntary
action, avoid or seek to avoid the observance or performance of any of the terms of this Note, and will at all times in good faith
carry out all of the provisions of this Note and take all action as may be required to protect the rights of the Holder of this
Note. Without limiting the generality of the foregoing or any other provision of this Note or the other Transaction Documents,
the Parent (a) shall not increase the par value of any shares of Parent Common Stock receivable upon conversion of this Note
above the Conversion Price then in effect, and (b) shall take all such actions as may be necessary or appropriate in order
that the Parent may validly and legally issue fully paid and nonassessable shares of Parent Common Stock upon each conversion
of this Note.


 


11.           RESERVATION
OF AUTHORIZED SHARES.


 


(a)       Reservation.
Commencing as of the Subscription Date and for as long as this Note remains outstanding (the “Share Reserve Period”),
the Parent shall at all times have and keep reserved (and shall not reduce such reserve) at least 200% of the maximum number of
shares of Parent Common Stock as shall from time to time be necessary to effect the full conversion of this Note (without regard
to any limitations or conversions and assuming for purposes of this Section 11(a) that this Note remains outstanding and is paid
in full in cash on May 15, 2020, and the redemption price on such date is the Event of Default Redemption Price (the “Required
Reserve Amount”).


 


(b)       Insufficient
Authorized Shares. If, notwithstanding Section 11(a), and not in limitation thereof, at any time while this Note
remains outstanding, the Parent does not have a sufficient number of authorized and unreserved shares of Parent Common Stock to
satisfy its obligation to reserve for issuance upon conversion of this Note at least a number of shares of Parent Common Stock
equal to the Required Reserve Amount (an “Authorized Share Failure”), then the Parent shall immediately take
all action necessary to increase the Parent authorized shares of Parent Common Stock to an amount sufficient to allow the Parent
to reserve the Required Reserve Amount for this Note. Without limiting the generality of the foregoing sentence, as soon as practicable
after the date of the occurrence of an Authorized Share Failure, but in no event later than ninety (90) days, after the occurrence
of such Authorized Share Failure, the Parent shall either (i) hold a meeting of its stockholders for the approval of an increase
in the number of authorized shares of Parent Common Stock, or (ii) have cured the Authorized Share Failure by, among other required
items, obtaining a written consent of the required percentage of holders of shares of Parent Common Stock for the required increase
in authorized shares and had taken any and all other such action necessary to rectify the Authorized Share Failure including,
but not limited to, providing the non-consenting stockholders with an information statement and a Form 14(C) and filed with the
SEC such Form 14(C). In connection with such meeting as set forth in (i) above, the Parent shall provide each stockholder with
a proxy statement and shall use its best efforts to solicit its stockholders’ approval of such increase in authorized shares
of Parent Common Stock and to cause its board of directors to recommend to the stockholders that they approve such proposal. In
the event that the Parent is prohibited from issuing shares of Parent Common Stock upon one or more conversions of this Note by
the Buyer pursuant to the terms of this Note due to the failure by the Parent to have sufficient shares of Parent Common Stock
available out of the authorized but unissued shares of Parent Common Stock (such unavailable number of shares of Parent Common
Stock, the “Authorized Failure Shares”), in lieu of delivering such Authorized Failure Shares to the Holder,
the Company shall pay cash in exchange for the redemption of such portion of the Conversion Amount convertible into such Authorized
Failure Shares at a price equal to the sum of (i) the product of (x) such number of Authorized Failure Shares multiplied
by (y)  the greatest Closing Sale Price or Closing Bid Price (as the case may be) of the Parent Common Stock on any Trading
Day during the period commencing on the date the Holder delivers the applicable Conversion Notice with respect to such Authorization
Failure Shares to the Parent and ending on the date of such issuance and payment under this Section 11(b) (or the Conversion
Price if the Parent and/or the Company is not then a Trading Issuer); and (ii) to the extent the Holder purchases (in an
open market transaction or otherwise) shares of Parent Common Stock to deliver in satisfaction of a sale by the Holder of Authorized
Failure Shares, any brokerage commissions and other out-of-pocket expenses, if any, of the Holder incurred in connection therewith.
Nothing contained in Section 11(a) or this Section 11(b) shall limit any obligations of the Parent and/or
the Company under any provision of this Note, the Securities Purchase Agreement and/or any other Transaction Document.


 






    	 	19	 



     

    

 


12.           REDEMPTIONS.


 


(a)       Mechanics.
The Company shall deliver the applicable Event of Default Redemption Price to the Holder in cash within five (5) Business Days
after the Company’s receipt of the Holder’s Event of Default Redemption Notice. If the Holder has submitted a Fundamental
Transaction Redemption Notice in accordance with Section 5(b), the Company shall deliver the applicable Fundamental
Transaction Redemption Price to the Holder in cash concurrently with the consummation of such Fundamental Transaction if such
notice is received prior to the consummation of such Fundamental Transaction and within five (5) Business Days after the
Company’s receipt of such notice otherwise. The Company shall deliver the applicable Company Optional Redemption Price to
the Holder in cash on the applicable Company Optional Redemption Date. Notwithstanding anything herein to the contrary, in connection
with any redemption hereunder at a time the Holder is entitled to receive a cash payment under any of the other Transaction Documents,
at the option of the Holder delivered in writing to the Company, the applicable Redemption Price hereunder shall be increased
by the amount of such cash payment owed to the Holder under such other Transaction Documents and, upon payment in full or conversion
in accordance herewith, shall satisfy the Company’s then payment obligation under such other Transaction Documents. In the
event of a redemption of less than all of the Conversion Amount of this Note (to the extent permitted hereunder), the Company
shall promptly cause to be issued and delivered to the Holder a new Note (in accordance with Section 19(d)) representing
the outstanding Principal which has not been redeemed. In the event that the Company does not pay the applicable Redemption Price
(together with Late Charges thereon), to the Holder within the time period required, at any time thereafter and until the Company
pays such unpaid Redemption Price (together with Late Charges thereon), in full, the Holder shall have the option, in lieu of
redemption, to require the Company to promptly return to the Holder all or any portion of this Note representing the Conversion
Amount that was submitted for redemption and for which the applicable Redemption Price (together with any Late Charges thereon)
has not been paid. Upon the Company’s receipt of such notice, (x) the applicable Redemption Notice shall be null and
void with respect to such Conversion Amount, and (y) the Company shall immediately return this Note, or issue a new Note
(in accordance with Section 19(d)), to the Holder, and in each case the Principal amount of this Note or such
new Note (as the case may be) shall be increased by an amount equal to the difference between (1) the applicable Redemption
Price (as the case may be, and as adjusted pursuant to this Section 12, if applicable) minus (2) the Principal
portion of the Conversion Amount submitted for redemption. The Holder’s delivery of a notice voiding a Redemption Notice
and exercise of its rights following such notice shall not affect the Company’s obligations to make any payments of Late
Charges which have accrued prior to the date of such notice with respect to the Conversion Amount subject to such notice.


 






    	 	20	 



     

    

 


13.          VOTING
RIGHTS. The Holder shall have no voting rights as the holder of this Note, except as required by law (including, without limitation,
the Delaware General Corporation Law) and as expressly provided in this Note.


 


14.          COVENANTS.
Until this Note has been converted, redeemed or otherwise satisfied in accordance with their terms:


 


(a)          Rank.
This Note shall rank (i) pari passu with all other Notes, if any, and (ii) be senior in all respects to all other Indebtedness
of the Company, other than Permitted Indebtedness secured by Permitted Liens if and to the extent the terms of such Indebtedness
requires such Indebtedness to be senior to all other Indebtedness of the Company.


 


(b)          Incurrence
of Indebtedness. Neither the Company nor the Parent shall, and the Company and the Parent shall cause all of the Subsidiaries
to not, directly or indirectly, incur or guarantee, assume or suffer to exist any Indebtedness (other than (i) the Indebtedness
evidenced by this Note and the Parent Note, and (ii) other Permitted Indebtedness, until the ninety-first (91st)
calendar day after the date this Note and the Parent Note is no longer outstanding.


 


(c)          Existence
of Liens. Neither the Company nor the Parent shall, and the Company and the Parent shall cause each Subsidiary to not, directly
or indirectly, allow or suffer to exist any mortgage, lien, pledge, charge, security interest or other encumbrance upon or in
any property or assets owned by the Company, the Parent and/or any of the Subsidiaries (collectively, “Liens”)
other than Permitted Liens.


 


(d)          Restricted
Payments. Neither the Company nor the Parent shall, and the Company and the Parent shall cause all of the Subsidiaries to
not, directly or indirectly, redeem, defease, repurchase, repay or make any payments in respect of, by the payment of cash or
cash equivalents (in whole or in part, whether by way of open market purchases, tender offers, private transactions or otherwise),
all or any portion of any Indebtedness of the Company, the Parent and/or any Subsidiary other than this Note and the Parent Note
and Permitted Indebtedness that is secured by a Permitted Lien (which by the terms of such particular Permitted Indebtedness the
payment thereof is senior in right of payment to the Parent Note and/or this Note), whether by way of payment in respect of principal
of (or premium, if any), interest on, such Indebtedness if at the time such payment is due or is otherwise made or, after giving
effect to such payment, (i) an event constituting an Event of Default has occurred and is continuing or (ii) an event
that with the passage of time and/or the giving of notice and without being cured would constitute an Event of Default has occurred
and is continuing.


 






    	 	21	 



     

    

 


(e)          Restriction
on Redemption and Cash Dividends. Until the ninety-first (91st) calendar day after the date no Securities are outstanding
and except as specifically provided below, neither the Company nor the Parent shall, and the Company and the Parent shall cause
each of the Subsidiaries to not, directly or indirectly, redeem, repurchase or declare or pay any cash dividend or distribution
on any of its Equity Interests other than intercompany dividends to the Parent, the Company or any Domestic Subsidiary (as defined
in the Securities Purchase Agreement), (“Intercompany Dividend”), provided no such Domestic Subsidiary shall
be permitted at any time to declare, pay and/or accrue any Intercompany Dividend, unless such Domestic Subsidiary’s operations
are located in the United States and it does not have any bank and/or similar accounts located outside of the United States; provided,
however, that notwithstanding anything to the contrary provided herein or elsewhere, all Intercompany Dividends otherwise
permitted in this Section 14(e), shall be prohibited during the period commencing on the date an Event of Default occurs
and is continuing through and including the tenth (10th) Business Day following the date the Collateral Agent receives
written notice from the Company and the Parent signed by the CEO (or the President) and the CFO of the Company and the Parent
that such Event of Default has been cured and no longer exists. For purposes hereof, “Equity Interests” means
(a) all shares of capital stock (whether denominated as common capital stock or preferred capital stock), equity interests, beneficial,
partnership or membership interests, joint venture interests, participations or other ownership or profit interests in or equivalents
(regardless of how designated) of or in a Person (other than an individual), whether voting or non-voting and (b) all securities
convertible into or exchangeable for any of the foregoing and all warrants, options or other rights to purchase, subscribe for
or otherwise acquire any of the foregoing, whether or not presently convertible, exchangeable or exercisable.


 


(f)           Restriction
on Transfer of Assets. Neither the Company nor the Parent shall, and the Company and the Parent shall cause all of the Subsidiaries
to not, directly or indirectly, sell, lease, license, assign, transfer, spin-off, split-off, close, convey or otherwise dispose
of any assets or rights of the Company, the Parent and/or any of the Subsidiaries whether in a single transaction or a series
of related transactions, other than (i) sales, leases, licenses, assignments, transfers, conveyances and other dispositions
of such assets or rights by the Company the Parent and the Subsidiaries in the ordinary course of business consistent with its
past practices and (ii) sales of inventory and product in the ordinary course of business.


 


(g)          Maturity
of Indebtedness. Neither the Company nor the Parent shall, and the Company and the Parent shall cause all of the Subsidiaries
to not, directly or indirectly, permit any Indebtedness of the Company, the Parent and/or any of the Subsidiaries to mature or
accelerate prior to the ninety-first (91st) calendar day after the date that this Note and the Parent Note is no longer
outstanding other than Permitted Indebtedness outstanding on the date hereof.


 


(h)          Change
in Nature of Business. Neither the Company nor the Parent shall, and the Company and the Parent shall cause each of the
Subsidiaries to not, directly or indirectly, make any change in the nature of its business including, but not limited to, engage
in any material line of business substantially different from those lines of business conducted by the Company, the Parent and
each of the Subsidiaries on the Subscription Date described in the Parent’s Annual Report on Form 10-K for the year ended
2016. Neither the Company nor the Parent shall, and the Company and the Parent shall cause each of the Subsidiaries to not, directly
or indirectly, modify its or their corporate structure or purpose.


 






    	 	22	 



     

    

 


(i)           Preservation
of Existence, Etc. The Company and the Parent shall maintain and preserve, and cause each of the Subsidiaries to maintain
and preserve, its existence, rights and privileges, and become or remain, and cause each of the Subsidiaries to become or remain,
duly qualified and in good standing in each jurisdiction in which the character of the properties owned or leased by it or in
which the transaction of its business makes such qualification necessary.


 


(j)           Maintenance
of Properties, Etc. The Company and the Parent shall maintain and preserve, and cause each of the Subsidiaries to maintain
and preserve, all of its properties which are necessary or useful in the proper conduct of its business in good working order
and condition, ordinary wear and tear excepted, and comply, and cause each of the Subsidiaries to comply, at all times with the
provisions of all leases to which it is a party as lessee or under which it occupies property, so as to prevent any loss or forfeiture
thereof or thereunder.


 


(k)          Maintenance
of Intellectual Property. The Company and the Parent will, and will cause each of the Subsidiaries to, take all action necessary
or advisable to maintain all of the Intellectual Property Rights (as defined in the Securities Purchase Agreement) of the Company,
the Parent and each of the Subsidiaries that are necessary or material to the conduct of its business in full force and effect.


 


(l)           Maintenance
of Insurance. The Company and the Parent shall maintain, and cause each of the Subsidiaries to maintain, insurance with responsible
and reputable insurance companies or associations (including, without limitation, comprehensive general liability, hazard, rent
and business interruption insurance) with respect to its properties (including all real properties leased or owned by it) and
business, in such amounts and covering such risks as is required by any governmental authority having jurisdiction with respect
thereto or as is carried generally in accordance with sound business practice by companies in similar businesses similarly situated.


 


(m)         Transactions
with Affiliates. Except as set forth under Section 14(e), neither the Company nor the Parent shall, nor shall the Company
or the Parent permit any of the Subsidiaries to, enter into, renew, extend or be a party to, any transaction or series of related
transactions (including, without limitation, the purchase, sale, lease, transfer or exchange of property or assets of any kind
or the rendering of services of any kind) with any Affiliate, except transactions (i) approved by a majority of the Company’s
and the Parent’s (as the case may be) independent directors, and (ii) in the ordinary course of business in a manner and
to an extent consistent with past practice and necessary or desirable for the prudent operation of its business, for fair consideration
and on terms no less favorable to the Company, the Parent and/or any of the Subsidiaries than would be obtainable in a comparable
arm’s length transaction with a Person that is not an Affiliate thereof.


 


(n)         Restricted
Issuances. The Company shall not directly and/or indirectly issue and/or sell any securities other than this Note and/or to
the Holder as required by this Note. The Parent shall not, directly or indirectly (i) issue any Parent Notes (other than
as contemplated by the Securities Purchase Agreement), (ii) issue any shares of preferred stock whose terms and rights (1) provide
the requirement or option to declare, accrue and pay a cash dividend while this Note and/or any Parent Note are outstanding and/or
(2) permit the redemption of such shares of preferred stock of the Parent while this Note and/or any Parent Note are outstanding,
and/or (iii) issue any other securities that would cause a breach or default under any of the Securities.


 






    	 	23	 



     

    

 


(o)          New
Subsidiaries; No Foreign Subsidiaries. Simultaneously with the acquisition or formation of each New Subsidiary, the Company
and the Parent shall take and the Parent and the Company shall cause all Subsidiaries including any New Subsidiary, to take any
and all actions under the Security Documents. None of the Company, the Parent or any Subsidiary shall directly and/or indirectly
make any payments to, or transfer any assets, including, but not limited to, by way of any dividend and/or distribution to any
Subsidiary including any Domestic Subsidiary if such Domestic Subsidiary is not located in the United States and/or has a bank
or similar account outside of the United States, without the prior written consent of the Holder.


 


(p)          Change
in Collateral; Collateral Records. The Company and the Parent shall each (i) give the Collateral Agent not less than thirty
(30) days’ prior written notice of any change in the location of any Collateral (as defined in the Security Documents),
other than to locations set forth in the Perfection Certificates (as defined in the Security Documents) hereto and with respect
to which the Collateral Agent has filed financing statements and otherwise fully perfected its Liens thereon (other than transfers
of inventory to customers in the ordinary course of business in a manner and to an extent consistent with past practice), (ii) advise
the Collateral Agent promptly, in sufficient detail, of any material adverse change relating to the type, quantity or quality
of the Collateral or the Lien granted thereon and (iii) execute and deliver, and cause each of the Subsidiaries to execute
and deliver, to the Collateral Agent for the benefit of the Holder from time to time, solely for the Collateral Agent’s
convenience in maintaining a record of Collateral, such written statements and schedules as the Collateral Agent or any Holder
may reasonably require, designating, identifying or describing the Collateral. In addition, the Company and the Parent shall provide
to the Collateral Agent upon filing, copies of all UCC-1 Financing Statements, amendments to all UCC-1 Financing Statements, all
UCC-3 filings and all other similar filings made with any Governmental Entity (as defined in the Securities Purchase Agreement)
including, but not limited to, the USPTO.


 


		(q)	[INTENTIONALLY
                                         LEFT BLANK]



 


(r)           Independent
Investigation. At the request of the Holder either (x) at any time when an Event of Default has occurred and is continuing,
(y) upon the occurrence of an event that with the passage of time or giving of notice would constitute an Event of Default
or (z) at any time the Holder reasonably believes an Event of Default may have occurred or be continuing, the Company and
the Parent shall hire an independent, reputable investment bank selected by the Company and the Parent and approved by the Holder
to investigate as to whether any breach of this Note has occurred (the “Independent Investigator”). If the
Independent Investigator determines that such breach of this Note has occurred, the Independent Investigator shall notify the
Company and the Parent of such breach and the Company and the Parent shall deliver written notice to each holder of a Note of
such breach. In connection with such investigation, the Independent Investigator may, during normal business hours, inspect all
contracts, books, records, personnel, offices and other facilities and properties of the Company, the Parent and each of the Subsidiaries
and, to the extent available to the Company and the Parent after the Company and the Parent uses reasonable efforts to obtain
them, the records of its legal advisors and accountants (including the accountants’ work papers) and any books of account,
records, reports and other papers not contractually required of the Company and the Parent to be confidential or secret, or subject
to attorney-client or other evidentiary privilege, and the Independent Investigator may make such copies and inspections thereof
as the Independent Investigator may reasonably request. The Company and the Parent shall furnish the Independent Investigator
with such financial and operating data and other information with respect to the business and properties of the Company and the
Parent as the Independent Investigator may reasonably request. The Company and the Parent shall permit the Independent Investigator
to discuss the affairs, finances and accounts of the Company and the Parent with, and to make proposals and furnish advice with
respect thereto to, the Company’s and the Parent’s officers, directors, key employees and independent public accountants
or any of them (and by this provision the Company and the Parent each authorize said accountants to discuss with such Independent
Investigator the finances and affairs of the Company, the Parent and the Subsidiaries), all at such reasonable times, upon reasonable
notice, and as often as may be reasonably requested.


 






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15.           SECURITY.
This Note is secured to the extent and in the manner set forth in the Transaction Documents (including, without limitation, the
Security Agreements, the other Security Documents and the Guaranties).


 


16.           DISTRIBUTION
OF ASSETS. In addition to all other rights and adjustments provided in this Note and/or any other Transaction Document or
elsewhere, if the Parent shall declare or make any dividend or other distributions of its assets (or rights to acquire its assets)
to any or all holders of shares of Parent Common Stock, by way of return of capital or otherwise (including without limitation,
any distribution of cash, stock or other securities (including, but not limited to, shares of Parent Common Stock and/or Common
Stock Equivalents), property or options by way of a dividend, spin off, reclassification, corporate rearrangement, scheme of arrangement
or other similar transaction) (the “Distributions”), then the Holder will be entitled to such Distributions
as if the Holder had held the number of shares of Parent Common Stock acquirable upon complete conversion of this Note (without
taking into account any limitations or restrictions on the convertibility of this Note and assuming for such purpose that this
Note was converted at the Conversion Price as of the applicable record date) immediately prior to the date on which a record is
taken for such Distribution or, if no such record is taken, the date as of which the record holders of Parent Common Stock are
to be determined for such Distributions (provided, however, that to the extent that the Holder’s right to participate in
any such Distribution would result in the Holder and the other Attribution Parties exceeding the Maximum Percentage, then the
Holder shall not be entitled to participate in such Distribution to the extent of the Maximum Percentage (and shall not be entitled
to beneficial ownership of such shares of Parent Common Stock as a result of such Distribution (and beneficial ownership) to the
extent of any such excess) and the portion of such Distribution shall be held in abeyance for the benefit of the Holder until
such time or times, if ever, as its right thereto would not result in the Holder and the other Attribution Parties exceeding the
Maximum Percentage, at which time or times the Holder shall be granted such Distribution (and any Distributions declared or made
on such initial Distribution or on any subsequent Distribution held similarly in abeyance) to the same extent as if there had
been no such limitation).


 






    	 	25	 



     

    

 


17.           AMENDING
THE TERMS OF THIS NOTE. The prior written consent of the Holder of this Note shall be required for any change, waiver or amendment
to this Note.


 


18.          TRANSFER.
This Note and any shares of Parent Common Stock issued and/or issuable upon conversion of this Note may be offered, sold, assigned
or transferred by the Holder without the consent of the Company, in whole or in part, at any time and from time to time, subject
only to the provisions of Section 2(g) of the Securities Purchase Agreement.


 


19.           REISSUANCE
OF THIS NOTE.


 


(a)          Transfer.
If this Note is to be transferred, the Holder shall surrender this Note to the Company, whereupon the Company will forthwith issue
and deliver upon the order of the Holder a new Note (in accordance with Section 19(d)), registered as the Holder may
request, representing the outstanding Principal being transferred by the Holder and, if less than the entire outstanding Principal
is being transferred, a new Note (in accordance with Section 19(d)) to the Holder representing the outstanding Principal
not being transferred. The Holder and any assignee, by acceptance of this Note, acknowledge and agree that, by reason of the provisions
of Section 3(c)(iii) following conversion or redemption of any portion of this Note, the outstanding Principal represented
by this Note may be less than the Principal stated on the face of this Note.


 


(b)          Lost,
Stolen or Mutilated Note. Upon receipt by the Company of evidence reasonably satisfactory to the Company of the loss, theft,
destruction or mutilation of this Note (as to which a written certification and the indemnification contemplated below shall suffice
as such evidence), and, in the case of loss, theft or destruction, of any indemnification undertaking by the Holder to the Company
in customary and reasonable form and, in the case of mutilation, upon surrender and cancellation of this Note, the Company shall
execute and deliver to the Holder a new Note (in accordance with Section 19(d)) representing the outstanding Principal.


 


(c)          Note
Exchangeable for Different Denominations. This Note is exchangeable, upon the surrender hereof by the Holder at the principal
office of the Company, for a new Note or Notes (in accordance with Section 19(d) and in principal amounts of at least
$1,000) representing in the aggregate the outstanding Principal of this Note, and each such new Note will represent such portion
of such outstanding Principal as is designated by the Holder at the time of such surrender.


 


(d)          Issuance
of New Notes; Signatures. Whenever the Company is required to issue a new Note pursuant to the terms of this Note, such new
Note (i) shall be of like tenor with this Note, (ii) shall represent, as indicated on the face of such new Note, the
Principal remaining outstanding (or in the case of a new Note being issued pursuant to Section 19(a) or Section 19(c),
the Principal designated by the Holder which, when added to the principal represented by the other new Notes issued in connection
with such issuance, does not exceed the Principal remaining outstanding under this Note immediately prior to such issuance of
new Notes), (iii) shall have an issuance date, as indicated on the face of such new Note, which is the same as the Issuance
Date of this Note, (iv) shall have the same rights, remedies and conditions as this Note, (v) shall represent accrued
and unpaid Interest and Late Charges on the Principal and Interest of this Note, from the Issuance Date, and (vi) shall be executed
by the Company.


 






    	 	26	 



     

    

 


20.          REMEDIES,
CHARACTERIZATIONS, OTHER OBLIGATIONS, BREACHES AND INJUNCTIVE RELIEF. The remedies provided in this Note shall be cumulative
and in addition to all other remedies available under this Note and any of the other Transaction Documents at law or in equity
(including a decree of specific performance and/or other injunctive relief), and nothing herein shall limit the Holder’s
right to pursue actual and consequential damages for any failure by the Company and/or the Parent to comply with the terms of
this Note. The Company and the Parent jointly and severally covenant to the Holder that there shall be no characterization concerning
this instrument other than as expressly provided herein. Amounts set forth or provided for herein with respect to payments, conversion,
redemptions and the like (and the computation thereof) shall be the amounts to be received by the Holder and shall not, except
as expressly provided herein, be subject to any other obligation of the Company and/or the Parent (or the performance thereof).
The Company and the Parent jointly and severally acknowledge that a breach by either of them of the obligations hereunder will
cause irreparable harm to the Holder and that the remedy at law for any such breach may be inadequate. The Company and the Parent
each therefore agree that, in the event of any such breach or threatened breach, the Holder shall be entitled, in addition to
all other available remedies, to specific performance and/or temporary, preliminary and permanent injunctive or other equitable
relief restraining and/or preventing any such breach or threatened breach without the necessity of showing economic harm and without
posting a bond or other security being required. The Company and the Parent shall provide all information and documentation to
the Holder that is requested by the Holder to enable the Holder to confirm the Company’s and the Parent’s compliance
with the terms and conditions of this Note (including, without limitation, compliance with Sections 4, 5 and 7).


 


21.          PAYMENT
OF COLLECTION, ENFORCEMENT AND OTHER COSTS. If (a) this Note is placed in the hands of an attorney for collection or
enforcement or is collected or enforced through any legal proceeding or the Holder otherwise takes action to collect amounts due
under this Note or to enforce the provisions of this Note or (b) there occurs any bankruptcy, reorganization, receivership
of the Company or other proceedings affecting Company’s creditors’ rights and involving a claim under this Note, then
the Company and the Parent shall jointly and severally be obligated and pay the costs incurred by the Holder for such collection,
enforcement or action or in connection with such bankruptcy, reorganization, receivership or other proceeding, including, without
limitation, attorneys’ fees and disbursements. The Company and the Parent expressly each acknowledge and agree that no amounts
due under this Note shall be affected, or limited, by the fact that the purchase price paid for this Note was less than the original
Principal amount hereof.


 


22.          CONSTRUCTION;
HEADINGS. This Note shall be deemed to be jointly drafted by the Company, the Parent and the initial Holder and shall not
be construed against any such Person as the drafter hereof. The headings of this Note are for convenience of reference and shall
not form part of, or affect the interpretation of, this Note. Unless the context clearly indicates otherwise, each pronoun herein
shall be deemed to include the masculine, feminine, neuter, singular and plural forms thereof. The terms “including, “includes,”
“include” and words of like import shall be construed broadly as if followed by the words “without limitation.”
The terms “herein,” “hereunder,” “hereof” and words of like import refer to this entire Note
instead of just the provision in which they are found. Unless expressly indicated otherwise, all section references are to sections
of this Note. Terms used in this Note and not otherwise defined herein, but defined in the other Transaction Documents, shall
have the meanings ascribed to such terms on the Closing Date in such other Transaction Documents unless otherwise consented to
in writing by the Holder.


 






    	 	27	 



     

    

 


23.           FAILURE
OR INDULGENCE NOT WAIVER. No failure or delay on the part of the Holder in the exercise of any power, right or privilege hereunder
shall operate as a waiver thereof, nor shall any single or partial exercise of any such power, right or privilege preclude other
or further exercise thereof or of any other right, power or privilege. No waiver shall be effective unless it is in writing and
signed by an authorized representative of the waiving party.


 


24.           DISPUTE
RESOLUTION.


 


		(a)	Submission
                                         to Dispute Resolution.



 


(i)           In
the case of a dispute relating to a Conversion Price, a Closing Sale Price, a Closing Bid Price, a Lowest Price, or a fair market
value or the arithmetic calculation of a Conversion Rate, any Redemption Price or any other calculation under this Note (as the
case may be) (including, without limitation, a dispute relating to the determination of any of the foregoing), the Company, the
Parent or the Holder (as the case may be) shall submit the dispute to the other party via facsimile or electronic mail (A) if
by the Company or the Parent, within five (5) Business Days after the occurrence of the circumstances giving rise to such
dispute or (B) if by the Holder, within five (5) Business Days after the Holder learned of the circumstances giving
rise to such dispute. If the Holder and the Company and/or the Parent are unable to promptly resolve such dispute relating to
such Conversion Price, such Lowest Price, such Closing Sale Price, such Closing Bid Price, or such fair market value or such arithmetic
calculation of such Conversion Rate, any such Redemption Price or any other calculation under this Note (as the case may be),
(including, without limitation, a dispute relating to the determination of any of the foregoing) at any time after the second
(2nd ) Business Day following such initial notice by the Company, the Parent or the Holder (as the case may
be) of such dispute to the Company, the Parent or the Holder (as the case may be), then the Holder and the Company shall together
select an independent, reputable investment bank to resolve such dispute and if they do not agree upon an independent, reputable
investment bank to resolve such dispute within a fifteen (15) day period, then the Holder shall be entitled to make such selection.


 






    	 	28	 



     

    

 


(ii)          The
Holder and the Company and/or the Parent (as applicable) shall each deliver to such investment bank (A) a copy of the initial
dispute submission so delivered in accordance with the first sentence of this Section 24 and (B) written documentation
supporting its position with respect to such dispute, in each case, no later than 5:00 p.m. (New York time) by the fifth (5h ) Business
Day immediately following the date on which the Holder selected such investment bank (the “Dispute Submission Deadline”)
(the documents referred to in the immediately preceding clauses (A) and (B) are collectively referred to herein as the
“Required Dispute Documentation”) (it being understood and agreed that if either the Holder, the Parent or
the Company fails to so deliver all of the Required Dispute Documentation by the Dispute Submission Deadline, then the party who
fails to so submit all of the Required Dispute Documentation shall no longer be entitled to (and hereby waives its right to) deliver
or submit any written documentation or other support to such investment bank with respect to such dispute and such investment
bank shall resolve such dispute based solely on the Required Dispute Documentation that was delivered to such investment bank
prior to the Dispute Submission Deadline). Unless otherwise agreed to in writing by both the Company and the Holder or otherwise
requested by such investment bank, neither the Company nor the Holder shall be entitled to deliver or submit any written documentation
or other support to such investment bank in connection with such dispute (other than the Required Dispute Documentation).


 


(iii)         The
Company, the Parent and the Holder (as the case may be) shall cause such investment bank to determine the resolution of such dispute
and notify the Company, the Parent and the Holder of such resolution no later than ten (10) Business Days immediately following
the Dispute Submission Deadline. The fees and expenses of such investment bank shall be borne solely by the Company in such dispute,
and such investment bank’s resolution of such dispute shall be final and binding upon all parties absent manifest error.


  


(b)          Miscellaneous.
The Company, the Parent and the Holder each expressly acknowledges and agrees that (i) this Section 24 constitutes
an agreement to arbitrate between the Company, the Parent and the Holder (and constitutes an arbitration agreement) under §
7501, et seq. of the New York Civil Practice Law and Rules (“CPLR”) and that the Holder is authorized to apply
for an order to compel arbitration pursuant to CPLR § 7503(a) in order to compel compliance with this Section 24,
(ii) a dispute relating to a Conversion Price, (iii) the terms of this Note and each other applicable Transaction Document
shall serve as the basis for the selected investment bank’s resolution of the applicable dispute, such investment bank shall
be entitled (and is hereby expressly authorized) to make all findings, determinations and the like that such investment bank determines
are required to be made by such investment bank in connection with its resolution of such dispute and in resolving such dispute
such investment bank shall apply such findings, determinations and the like to the terms of this Note and any other applicable
Transaction Documents, (iv) the Holder (and only the Holder), in its sole discretion, shall have the right to submit any dispute
described in this Section 24 to any state or federal court sitting in The City of New York, Borough of Manhattan in
lieu of utilizing the procedures set forth in this Section 24 and (v) nothing in this Section 24
shall limit the Holder from obtaining any injunctive relief or other equitable remedies (including, without limitation, with respect
to any matters described in this Section 24).


 






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25.          NOTICES;
CURRENCY; PAYMENTS.


 


(a)          Notices.
Whenever notice is required to be given under this Note, unless otherwise provided herein, such notice shall be given in accordance
with Section 9(f) of the Securities Purchase Agreement. The Company and the Parent shall provide the Holder with prompt
written notice of all actions taken pursuant to this Note, including in reasonable detail a description of such action and the
reason therefore. Without limiting the generality of the foregoing, the Company and the Parent will give written notice to the
Holder (i) immediately upon any adjustment of the Conversion Price, setting forth in reasonable detail, and certifying, the
calculation of such adjustment and (ii) at least fifteen (15) days prior to the date on which the Company or the Parent
closes its books or takes a record (A) with respect to any dividend or distribution upon the Parent Common Stock, and/or
(B) for determining rights to vote with respect to any Fundamental Transaction, dissolution or liquidation, provided in each
case that such information shall be made known to the public prior to or in conjunction with such notice being provided to the
Holder.


 


(b)           Currency.
All dollar amounts referred to in this Note are in United States Dollars (“U.S. Dollars”), and all amounts
owing under this Note shall be paid in U.S. Dollars. All amounts denominated in other currencies (if any) shall be converted into
the U.S. Dollar equivalent amount in accordance with the Exchange Rate on the date of calculation. “Exchange Rate”
means, in relation to any amount of currency to be converted into U.S. Dollars pursuant to this Note, the U.S. Dollar exchange
rate as published in the Wall Street Journal on the relevant date of calculation (it being understood and agreed that where an
amount is calculated with reference to, or over, a period of time, the date of calculation shall be the final date of such period
of time).


 


(c)           Payments.
Whenever any payment of cash is to be made by the Company and/or the Parent to any Person pursuant to this Note, such payment
shall be made in lawful money of the United States of America by a certified check drawn on the account of the Company and/or
the Parent (as the case may be) and sent via overnight courier service to such Person at such address as previously provided to
the Company and/or the Parent in writing (which address, in the case of the Holder, shall initially be as set forth in the Securities
Purchase Agreement), provided that the Holder may elect to receive a payment of cash via wire transfer of immediately available
funds by providing the Company with prior written notice setting out such request and the Holder’s wire transfer instructions.
Whenever any amount expressed to be due by the terms of this Note is due on any day which is not a Business Day, the same shall
instead be due on the next succeeding day which is a Business Day. Any amount of Principal, Interest, Late Charges and/or other
amounts due under this Note and the other Transaction Documents which is not paid when due (following any cure period, if any)
shall result in a late charge being incurred and payable by the Company in an amount equal to interest on such amount at the rate
of eighteen percent (18%) per annum from the date such amount was due until the same is paid in full (“Late Charge”).


 


26.          CANCELLATION.
After all Principal, accrued Interest, Late Charges and other amounts at any time owed on this Note have been paid in full, this
Note shall automatically be deemed canceled, shall be surrendered to the Company for cancellation and shall not be reissued.


 






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27.          WAIVER
OF NOTICE. To the maximum extent permitted by law, the Company and the Parent each hereby irrevocably waives demand, notice,
presentment, protest and all other demands and notices in connection with the delivery, acceptance, performance, default or enforcement
of this Note, the Parent Note, the Parent Warrant, the Securities Purchase Agreement and the other Transaction Documents.


 


28.          GOVERNING
LAW. All questions concerning the construction, validity, enforcement and interpretation of this Note shall be governed by
the internal laws of the State of New York, without giving effect to any choice of law or conflict of law provision or rule (whether
of the State of New York or any other jurisdictions) that would cause the application of the laws of any jurisdictions other than
the State of New York. Except as expressly set forth in Section 24, the Company and the Parent hereby irrevocably submit
to the exclusive jurisdiction of the state and federal courts sitting in The City of New York, Borough of Manhattan, for the adjudication
of any dispute hereunder or in connection herewith or with any transaction contemplated hereby or discussed herein, and hereby
irrevocably waives, and agrees not to assert in any suit, action or proceeding, any claim that it is not personally subject to
the jurisdiction of any such court, that such suit, action or proceeding is brought in an inconvenient forum or that the venue
of such suit, action or proceeding is improper. The Company, the Parent and the Holder each hereby irrevocably waives personal
service of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof to such
party at the address for such notices to it under this Note and agrees that such service shall constitute good and sufficient
service of process and notice thereof. Nothing contained herein or elsewhere, shall be deemed to limit in any way any right to
serve process in any manner permitted by law. Nothing contained herein or elsewhere, (i) shall be deemed or operate to preclude
the Holder from directly and/or indirectly bringing suit or taking other legal action against the Company, the Parent and/or any
of the Subsidiaries and/or Affiliates or other Persons in any other jurisdiction to protect and/or enforce the Holders rights
under this Note and/or the other Transaction Documents including the Securities Purchase Agreement, the Warrant, the Security
Documents and the Guarantees and/or collect on the Company’s and/or the Parent’s obligations to the Holder or to enforce
a judgment or other court ruling in favor of the Holder or (ii) shall limit, or shall be deemed or construed to limit any provision
of Section 24. THE COMPANY AND THE HOLDER EACH HEREBY IRREVOCABLY WAIVES ANY RIGHT IT MAY HAVE TO, AND AGREES NOT TO
REQUEST, A JURY TRIAL FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR UNDER ANY OTHER TRANSACTION DOCUMENT OR IN CONNECTION WITH
OR ARISING OUT OF THIS NOTE, OR ANY TRANSACTION CONTEMPLATED HEREBY OR THEREBY.


 


29.           JUDGMENT
CURRENCY.


 


(a)           If
for the purpose of obtaining or enforcing judgment against the Company in any court in any jurisdiction it becomes necessary to
convert into any other currency (such other currency being hereinafter in this Section 29 referred to as the “Judgment
Currency”) an amount due in U.S. Dollars under this Note, the conversion shall be made at the Exchange Rate prevailing
on the Trading Day immediately preceding:


 


(i)           the
date actual payment of the amount due, in the case of any proceeding in the courts of New York or in the courts of any other jurisdiction
that will give effect to such conversion being made on such date: or


 


(ii)          the
date on which the foreign court determines, in the case of any proceeding in the courts of any other jurisdiction (the date as
of which such conversion is made pursuant to this Section 29(a)(ii) being hereinafter referred to as the “Judgment
Conversion Date”).


 






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(b)          If
in the case of any proceeding in the court of any jurisdiction referred to in Section 29(a)(ii) above, there is a
change in the Exchange Rate prevailing between the Judgment Conversion Date and the date of actual payment of the amount due,
the applicable party shall pay such adjusted amount as may be necessary to ensure that the amount paid in the Judgment Currency,
when converted at the Exchange Rate prevailing on the date of payment, will produce the amount of U.S. Dollars which could have
been purchased with the amount of Judgment Currency stipulated in the judgment or judicial order at the Exchange Rate prevailing
on the Judgment Conversion Date.


 


(c)          Any
amount due from the Company and/or the Parent under this provision shall be due as a separate debt and shall not be affected by
judgment being obtained for any other amounts due under or in respect of this Note.


 


30.          SEVERABILITY.
If any provision of this Note is prohibited by law or otherwise determined to be invalid or unenforceable by a court of competent
jurisdiction, the provision that would otherwise be prohibited, invalid or unenforceable shall be deemed amended to apply to the
broadest extent that it would be valid and enforceable, and the invalidity or unenforceability of such provision shall not affect
the validity of the remaining provisions of this Note so long as this Note as so modified continues to express, without material
change, the original intentions of the parties as to the subject matter hereof and the prohibited nature, invalidity or unenforceability
of the provision(s) in question does not substantially impair the respective expectations or reciprocal obligations of the parties
or the practical realization of the benefits that would otherwise be conferred upon the parties. The parties will endeavor in
good faith negotiations to replace the prohibited, invalid or unenforceable provision(s) with a valid provision(s), the effect
of which comes as close as possible to that of the prohibited, invalid or unenforceable provision(s).


 


31.          MAXIMUM
PAYMENTS. Without limiting Section 9(d) of the Securities Purchase Agreement, nothing contained herein shall be
deemed to establish or require the payment of a rate of interest or other charges in excess of the maximum permitted by applicable
law. In the event that the rate of interest required to be paid or other charges hereunder exceed the maximum permitted by such
law, any payments in excess of such maximum shall be credited against amounts owed by the Company and/or the Parent to the Holder
and thus refunded to the Company and/or the Parent.


 






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32.          CERTAIN
DEFINITIONS. For purposes of this Note, the following terms shall have the following meanings:


 


(a)          “1933
Act” means the Securities Act of 1933, as amended, and the rules and regulations thereunder.


 


(b)          “1934
Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations thereunder.


 


(c)          “Affiliate”
or “affiliate” means, with respect to any Person, any other Person that directly or indirectly controls, is
controlled by, or is under common control with, such Person, it being understood for purposes of this definition that “control”
of a Person means the power directly or indirectly either to vote 10% or more of the stock having ordinary voting power for the
election of directors of such Person or direct or cause the direction of the management and policies of such Person whether by
contract or otherwise.


 


(d)          “Attribution
Parties” means, collectively, the following Persons and entities: (i) any investment vehicle, including, any funds,
feeder funds or managed accounts, currently, or from time to time after the Issuance Date, directly or indirectly managed or advised
by the Holder’s investment manager or any of its Affiliates or principals, (ii) any direct or indirect Affiliates of
the Holder or any of the foregoing, (iii) any Person acting or who could be deemed to be acting as a Group together with
the Holder or any of the foregoing and (iv) any other Persons whose beneficial ownership of the Parent Common Stock would
or could be aggregated with the Holder’s and the other Attribution Parties for purposes of Section 13(d) of the 1934
Act. For clarity, the purpose of the foregoing is to subject collectively the Holder and all other Attribution Parties to the
Maximum Percentage.


 


(e)          “Bloomberg”
means Bloomberg, L.P.


 


(f)           “Business
Day” means any day other than Saturday, Sunday or other day on which commercial banks in The City of New York are authorized
or required by law to remain closed.


 


(g)         
“Closing Date” shall have the meaning set forth in the Securities Purchase Agreement, which date is the date
the Company initially issued this Note pursuant to the terms of the Securities Purchase Agreement.


 


(h)          “Closing
Bid Price” and “Closing Sale Price” means, for any security as of any date, the last closing bid
price and last closing trade price, respectively, for such security on the Principal Market, as reported by Bloomberg, or, if
the Principal Market begins to operate on an extended hours basis and does not designate the closing bid price or the closing
trade price (as the case may be) then the last bid price or last trade price, respectively, of such security prior to 4:00:00
p.m., New York time, as reported by Bloomberg, or, if the Principal Market is not the principal securities exchange or trading
market for such security, the last closing bid price or last trade price, respectively, of such security on the principal securities
exchange or trading market where such security is listed or traded as reported by Bloomberg, or if the foregoing do not apply,
the last closing bid price or last trade price, respectively, of such security in the over-the-counter market on the electronic
bulletin board for such security as reported by Bloomberg, or, if no closing bid price or last trade price, respectively, is reported
for such security by Bloomberg, the average of the bid prices, or the ask prices, respectively, of any market makers for such
security as reported in the “pink sheets” by OTC Markets Group Inc. (formerly Pink Sheets LLC). If the Closing Bid
Price or the Closing Sale Price cannot be calculated for a security on a particular date on any of the foregoing bases, the Closing
Bid Price or the Closing Sale Price (as the case may be) of such security on such date shall be the fair market value as mutually
determined by the Company and the Holder. If the Company and the Holder are unable to agree upon the fair market value of such
security, then such dispute shall be resolved in accordance with the procedures in Section 24. All such determinations
shall be appropriately adjusted for any stock splits, stock dividends, stock combinations, recapitalizations or other similar
transactions during such period. 


 






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(i)           “Collateral
Agent” shall have the meaning set forth in the Securities Purchase Agreement.


 


(j)          
“Convertible Securities” means any stock or other security (other than Options) that is at any time and under
any circumstances, directly or indirectly, convertible into, exercisable or exchangeable for, or which otherwise entitles the
holder thereof to acquire, any shares of Parent Common Stock.


 


(k)          “Current
Subsidiary” means any Person in which the Company or the Parent on the Subscription Date, directly or indirectly, (i) owns
a majority of the outstanding capital stock, voting stock or holds a majority of the equity or similar interest of such Person
or (ii) controls or operates a substantial portion of the business, operations, management or administration of such Person,
and all of the foregoing, collectively, “Current Subsidiaries”.


 


(l)           “Eligible
Market” means any of the following markets or exchanges on which the Parent Common Stock (or any other common stock
of any other Person that references an Eligible Market for its common stock) is listed or quoted for trading on the date in question:
the OTC Bulletin Board, the NASDAQ Global Market, the NASDAQ Global Select Market, the NASDAQ Capital Market, the New York Stock
Exchange, NYSE Arca, the NYSE MKT, or the OTCQX Marketplace, the OTCQB Marketplace, the OTCPink Marketplace or any other tier
operated by OTC Markets Group Inc. (or any successor to any of the foregoing).


 


(m)         “Fundamental
Transaction” means that (i) the Company, the Parent and/or any of the Subsidiaries shall, directly or indirectly, in
one or more or a series of related transactions, (1) consolidate or merge with or into (whether or not the Company and/or the
Parent and/or any of the Subsidiaries is the surviving corporation) any other Person and/or each other, or (2) sell, lease, license,
assign, transfer, convey or otherwise dispose of all or substantially all of its respective properties or assets to any other
Person, or (3) allow any other Person to make a purchase, tender or exchange offer that is accepted by the holders of more than
50% of the outstanding shares of Voting Stock of the Company and/or the Parent (not including any shares of Voting Stock of the
Company and/or the Parent held by the Person or Persons making or party to, or associated or affiliated with the Persons making
or party to, such purchase, tender or exchange offer), or (4) consummate a stock or share purchase agreement or other business
combination (including, without limitation, a reorganization, recapitalization, spin-off or scheme of arrangement) with any other
Person whereby such other Person acquires more than 50% of the outstanding shares of Voting Stock of the Company and/or the Parent
(not including any shares of Voting Stock of the Company, the Parent and/or any Subsidiary and/or the Company held by the other
Person or other Persons making or party to, or associated or affiliated with the other Persons making or party to, such stock
or share purchase agreement or other business combination), or (ii) any “person” or “group” (as these
terms are used for purposes of Sections 13(d) and 14(d) of the 1934 Act and the rules and regulations promulgated thereunder)
is or shall become the “beneficial owner” (as defined in Rule 13d-3 under the 1934 Act), directly or indirectly, of
50% of the aggregate ordinary voting power represented by issued and outstanding Voting Stock of the Company and/or the Parent.
Notwithstanding anything to the contrary provided herein or elsewhere, nothing in this definition of Fundamental Transaction shall
provide any right to the Company or the Parent to do or take any actions otherwise prohibited herein and/or in the other Transaction
Documents. Notwithstanding the above, a Fundamental Transaction shall not be deemed to occur as a result of a reincorporation
merger of the Parent provided other than the place of incorporation of the Parent no other material changes occur to the Parent
and/or any rights of the Holder under this Note and/or any other Transaction Document, as a result of such reincorporation merger.


 






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(n)          “GAAP”
means United States generally accepted accounting principles, consistently applied.


 


(o)          “Indebtedness”
shall have the meaning ascribed to such term in the Securities Purchase Agreement.


 


(p)         
“Interest Date” means the first (1st) calendar day of each calendar month beginning with the first
calendar day of the first month following the Closing Date.


 


(q)          “Material
Adverse Effect” means any material adverse effect on (i) the business, properties, assets, liabilities, operations
(including results thereof), condition (financial or otherwise) or prospects of the Company, the Parent and/or any of the Subsidiaries,
individually or taken as a whole, (ii) the transactions contemplated hereby or in any of the other Transaction Documents
or any other agreements or instruments to be entered into in connection herewith or therewith or (iii) the authority or ability
of the Company, the Parent and/or any of the Subsidiaries to perform any of the obligations under any of the Transaction Documents.


 


(r)           [INTENTIONALLY
LEFT BLANK]


 


(s)          “New
Subsidiary” means, as of any date of determination, any Person in which the Company and/or the Parent after the Subscription
Date, directly or indirectly, (i) owns or acquires a majority of the outstanding capital stock, voting stock, or holds a
majority of the equity or similar interest of such Person or (ii) controls or operates a substantial portion of the business,
its management, operations or administration of such Person, and all of the foregoing, collectively, “New Subsidiaries”.


 


(t)           “Options”
means any rights, warrants or options to subscribe for or purchase shares of Parent Common Stock or Convertible Securities.


 


(u)          “Parent
Common Stock” means (i) the shares of common stock, $0.001 par value per share of the Parent, and (ii) any
capital stock into which such common stock shall have been changed or any share capital resulting from a reclassification of such
common stock.


 


(v)         “Parent
Entity” of a Person means an entity that, directly or indirectly, controls the applicable Person or, if there is more
than one such Person or Parent Entity, the Person or Parent Entity with the largest public market capitalization (or if both are
not Trading Issuers, the largest private company valuation, as determined by the Holder) as of the date of consummation of the
Fundamental Transaction.


 


(w)        “Parent
Note” has the meaning set forth in the Securities Purchase Agreement.


 


(x)          “Parent
Warrants” has the meaning ascribed to such term in the Securities Purchase Agreement, and shall include all warrants
issued in exchange therefor or replacement thereof.


 


(y)         “Permitted
Indebtedness” means (i) Indebtedness of the Company under this Note and/or any other Transaction Document, (ii) Indebtedness
of the Company expressly identified as such on Schedule 3(q) to the Securities Purchase Agreement, as in effect as of the
Subscription Date including, but not limited to, Sanofi Indebtedness to the extent such Sanofi Indebtedness is secured by a Permitted
Lien, (iii) Indebtedness of the Company incurred pursuant to accounts receivable financing, provided if such is secured it is
secured solely by the accounts receivable of the Company, (iv) Indebtedness incurred for the acquisition of services, supplies
or inventory on normal trade credit in the ordinary course of business; (v) Indebtedness secured by Permitted Liens or unsecured
as described in clauses (iv) and (v) of the definition of Permitted Liens and (vi) intercompany Indebtedness (to the extent not
prohibited by the Sanofi Documents) between the Company, the Parent and any wholly-owned Domestic Subsidiary of the Parent, to
the extent so permitted under this Note and the other Transaction Documents.


 






    	 	35	 



     

    

 


(z)         
“Permitted Liens” means (i) any Lien for taxes not yet due or delinquent or being contested in good faith by
appropriate proceedings for which adequate reserves have been established in accordance with GAAP, (ii) any statutory Lien arising
in the ordinary course of business of the Company by operation of law with respect to a liability of the Company that is not yet
due or delinquent, (iii) any Lien created by operation of law, such as materialmen’s liens, mechanics’ liens and other
similar liens, arising in the ordinary course of business of the Company with respect to a liability of the Company that is not
yet due or delinquent or that are being contested in good faith by appropriate proceedings, (iv) Liens (A) upon or in any equipment
acquired or held by the Company solely to secure the purchase price of such equipment or Indebtedness incurred solely for the
purpose of financing the acquisition or lease of such equipment of the Company, or (B) existing on such equipment at the time
of its acquisition, provided that the Lien is confined solely to the property of the Company so acquired and improvements thereon,
and the proceeds of such equipment, in either case, with respect to Indebtedness in an aggregate amount not to exceed $250,000,
(v) Liens incurred in connection with the extension, renewal or refinancing of the Indebtedness secured by Liens of the type
described in clause (iv) above, provided that any extension, renewal or replacement Lien shall be limited to the property encumbered
by the existing Lien and the principal amount of the Indebtedness being extended, renewed or refinanced does not increase, (vi)
Liens in favor of customs and revenue authorities arising as a matter of law to secure payments of custom duties in connection
with the importation of goods for the Company, (viii) Liens with respect to accounts receivable and inventory financing of the
Company provided such Liens are solely on the accounts receivable of the Company that are being used to obtain such accounts receivable
financing for the Company as expressly identified and in such amounts as provided in writing in such accounts receivable financing
documentation, (ix) Liens in favor of Sanofi to the extent permitted in the Deed of Trust as of the Subscription Date, and (x)
Liens in favor of the Collateral Agent and/or the Holder perfecting the Collateral Agent’s and/or the Holder’s security
interests in the assets of the Company to the extent provided for in the Security Documents.


 


(aa)      
“Person” means an individual, a limited liability company, a partnership, a joint venture, a corporation, a
trust, an unincorporated organization, any other entity or a government or any department or agency thereof.


 


(bb)       “Principal
Market” means as of a particular date, the Eligible Market on such date that the Parent Common Stock is principally
traded or quoted on.


 


(cc)        “Qualifying
PO” means the first firm commitment underwritten public offering by the Parent on or following the Subscription Date
in which shares of Parent Common Stock are sold for the account of the Parent solely for cash to the public resulting in proceeds
to the Parent and/or the Company of no less than $8,000,000 (after deduction only of underwriter discounts and commissions) and
where the shares of Parent Common Stock registered under the 1933 Act and sold in such public offering, are simultaneously listed
and commence trading on the Nasdaq Global Market, the Nasdaq Global Select Market, the Nasdaq Capital Market, the New York Stock
Exchange or the NYSE Market (a “Qualify Market”).


 


(dd)        “Redemption
Notices” means, collectively, the Event of Default Redemption Notices, the Fundamental Transaction Redemption Notices
and the Company Optional Redemption Notices and each of the foregoing, individually, a “Redemption Notice.”


 


(ee)        “Redemption
Prices” means, collectively, the Company Optional Redemption Prices, Event of Default Redemption Prices, Fundamental
Transaction Redemption Prices and each of the foregoing, individually, a “Redemption Price.”


 






    	 	36	 



     

    

 


(ff)          “SEC”
means the United States Securities and Exchange Commission or any successor thereto.


 


(gg)        “Securities
Purchase Agreement” shall have the meaning set forth on the first page of this Note.


 


(hh)       
“Security Agreements” shall have the meaning as set forth in the Securities Purchase Agreement.


 


(ii)           “Security
Documents” shall have the meaning as set forth in the Securities Purchase Agreement.


 


(jj)          “Subsidiaries”
means, as of any date of determination, collectively, all Current Subsidiaries including, but not limited to, all New Subsidiaries,
and each of the foregoing, individually, a “Subsidiary.”


 


(kk)       “Successor
Entity” means the Person (or, if so elected by the Holder, the Parent Entity) formed by, resulting from or surviving
any Fundamental Transaction or the Person (or, if so elected by the Holder, the Parent Entity) with which such Fundamental Transaction
shall have been entered into.


 


(ll)         “Trading
Day” means, (I) as applicable, (x) with respect to all price or trading volume determinations relating to the Parent
Common Stock, any day on which the Parent Common Stock is traded on the Principal Market, or, if the Principal Market is not the
principal trading market for the Parent Common Stock, then on an Eligible Market the principal securities exchange or securities
market on which the Parent Common Stock is then traded or eligible for quotation, provided that “Trading Day” shall
not include any day on which the Parent Common Stock is scheduled to trade on such exchange or market for less than 4.5 hours
or any day that the Parent Common Stock is suspended from trading or quotation during the final hour of trading on such exchange
or market (or if such exchange or market does not designate in advance the closing time of trading on such exchange or market,
then during the hour ending at 4:00:00 p.m., New York time) unless such day is otherwise designated as a Trading Day in writing
by the Holder or (y) with respect to all determinations other than price determinations relating to the Parent Common Stock,
any day on which The New York Stock Exchange (or any successor thereto) is open for trading of securities, or (II) if the Parent
is not a Trading Issuer, the term “Trading Day” shall mean Business Day.


 


(mm)      “Trading
Issuer” means any Person whose shares of common stock are listed for trading or eligible for quotation on an Eligible
Market.


 


(nn)       “Transaction
Documents” shall have the meaning as set forth in the Securities Purchase Agreement.


 


(oo)       
“Voting Stock” of a Person means capital stock of such Person of the class or classes pursuant to which the
holders thereof have the general voting power to elect, or the general power to appoint, at least a majority of the board of directors,
managers, trustees or other similar governing body of such Person (irrespective of whether or not at the time capital stock of
any other class or classes shall have or might have voting power by reason of the happening of any contingency).


 






    	 	37	 



     

    

 


33.           DISCLOSURE.
Upon receipt or delivery by the Company or the Parent of any notice in accordance with the terms of this Note and subject to the
other terms of this Section 33, unless the Company or the Parent has in good faith determined that the matters relating
to such notice do not constitute material, non-public information relating to the Company, the Parent and/or any of the Subsidiaries
or the Holder has provided prior written consent to receive such material non-public information, the Company shall and the Parent
shall within two (2) Trading Days after any such receipt or delivery publicly disclose such material, non-public information
on a Current Report on Form 8-K or otherwise. In the event that the Company or the Parent believes that a notice contains material,
non-public information relating to the Company, the Parent and/or any of the Subsidiaries, the Company and/or the Parent so shall
indicate to the Holder contemporaneously with delivery of such notice, and in the absence of any such indication, the Holder shall
be allowed to presume that all matters relating to such notice do not constitute material, non-public information relating to
the Company, the Parent and/or any of the Subsidiaries. If the Company, the Parent and/or any of the Subsidiaries provides material
non-public information to the Holder that is not simultaneously filed in a Current Report on Form 8-K and the Holder has not agreed
in writing to receive such material non-public information, the Company and the Parent hereby covenant and agree that the Holder
shall not have any duty of confidentiality to them and/or the Subsidiaries or any of the officers, directors, employees, affiliates
or agents with respect to, any such information or a duty to any of the foregoing not to trade on the basis of such material non-public
information. Nothing contained in this Section 33 shall limit any obligations of the Company and/or the Parent, or
any rights or remedies of the Holder, under the Securities Purchase Agreement. Notwithstanding anything to the contrary contained
herein, neither the Parent, the ICA-T nor any Subsidiary shall be required to publicly disclose any material, non-public information
relating to the Parent, ICA-T or any Subsidiary if the Holder has provided its prior written consent to the receipt of such information.


  




    	 	38	 



     

    

 


[SENIOR
SECURED CONVERTIBLE NOTE – SIGNATURE PAGE]


  


IN
WITNESS WHEREOF, the Company and Parent has caused this Note to be duly executed as of the Issuance Date set out above.


  


	 	ICAGEN-T INC.
	 	 	 
	 	By:	/s/
Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    Chief Executive Officer


 


	 	ICAGEN, INC.
	 	 	 
	 	By:	/s/
Richard Cunningham
	 	 	Name:
    Richard Cunningham
	 	 	Title:
    Chief Executive Officer


 




    	 	39	 



     

    

 


EXHIBIT
I


 


Icagen,
Inc. Conversion Notice


 


Reference
is made to the Senior Secured Convertible Note (the “Note”) issued to the undersigned by Icagen-T, Inc., a
Delaware corporation (the “Company”). In accordance with and pursuant to the Note, the undersigned hereby elects
to convert the Conversion Amount (as defined in the Note) of the Note indicated below into shares of common stock, $0.001 par
value per share (the “Parent Common Stock”), of Icagen, Inc., as of the date specified below. Capitalized terms
not defined herein shall have the meaning as set forth in the Note.


 





	 	Date
    of Conversion:	 
	 	 	 
	 	Aggregate
    Principal to be converted:	 
	 	 	 
	 	Aggregate
    accrued and unpaid Interest to be converted:	 
	 	 	 
	 	Aggregate
    accrued and unpaid Late Charges with respect to such portion of the Aggregate Principal and Aggregate Interest to be converted:	 
	 	 	 
	 	AGGREGATE
    CONVERSION	 
	 	AMOUNT
    TO BE CONVERTED:	 


 


Please
confirm the following information:


 


	 	Conversion
    Price:	 
	 	 	 
	 	Number
    of shares of Common Stock to be issued:	 


 


Please
issue the shares of Parent Common Stock into the Note is being converted to Holder, or for its benefit, as
follows:


 


☐  Check
here if requesting delivery as a certificate to the following name and to the following address:


 


	 	Issue
    to:	 
	 	 	 
	 	 	 


 




    i

     

    

 


☐  Check
here if requesting delivery by Deposit/Withdrawal at Custodian as follows if the Company is a Trading Issuer:




 


	 	DTC
    Participant:	 
	 	 	 
	 	DTC
    Number:	 
	 	 	 
		Account
    Number:	 


 


Notwithstanding
anything to the contrary contained herein, this Conversion Notice shall constitute a representation by the Holder of the Note
submitting this Conversion Notice that after giving effect to the conversion provided for in this Conversion Notice, such Holder
(together with its affiliates) will not have beneficial ownership (together with the beneficial ownership of such Person’s
affiliates) of a number of shares of Parent Common Stock which exceeds the Maximum Percentage (as defined in the Note) of the
total outstanding shares of Parent Common Stock as determined pursuant to the provisions of Section 3(d) of the Note.


 





	Date:
    _____________ __, 	 
	 	 
		 
	Name
    of Registered Holder	 


 


	By:
    	 	 	 
	 	Name:
    	 	 
	 	Title:	 	 
	 	 	 	 
	 	Tax
    ID: ____________________________	 	 
	 	 	 	 
	 	Facsimile:
__________________________    	 	 
	 	 	 	 
	 	E-mail
    Address: ______________________	 	 


 




    ii

     

    

 


Exhibit
II


 


ACKNOWLEDGMENT


 


Icagen,
Inc. and Icagen-T, Inc. hereby (a) acknowledge this Conversion Notice, (b) certify that the above indicated number of shares
of Parent Common Stock [are][are not] eligible to be resold by the Holder either (i) pursuant to Rule 144 (subject to the
Holder’s execution and delivery to the Company of a customary 144 representation letter) or (ii) an effective and
available registration statement and (c) hereby directs _________________ to issue the above indicated number of shares of
Parent Common Stock in accordance with the Transfer Agent Instructions dated May 15, 2017 from Icagen, Inc. and acknowledged
and agreed to by American Stock Transfer & Trust Company.


 


 


	 	ICAGEN,
    INC. 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:


 





	 	ICAGEN-T, INC. 
	 	 	 
	 	By:	 
	 	 	Name:
	 	 	Title:



 


 


i