# Patent

## Title
Method of molding skin-covered foamed plastic article

## Abstract

Various modifications and alterations of this invention will become apparent to those skilled in the art without departing from the scope and spirit of this invention, and it should be understood that this invention is not to be unduly limited to the illustrative embodiments set forth herein.

## Background
## Claims

1. A process for preparing a hydroxy-substituted polymeric shaped article comprising the steps: at least 100.degree. C. comprising the product of an ethylenically-unsaturated monomer bearing at least one trihaloacetoxy-substitent group, by heating in a mold or pressing into sheets or films at a temperature in the range of 150.degree. to 400.degree. C. for 5 seconds to 15 minutes, and then cooling the resulting thermoformed polymer, to provide a thermoplastic, hydrogel precursor shaped article, causes displacement of said trihaloacetoxy group to provide a hydroxy-substituted polymeric shaped article, said solvolyzing step taking place in the presence of a diluent which is not a solvent for said thermoformed polymer.

2. The process according to claim 1 further comprising the step: hydrogel article.

3. The process according to claim 2 wherein said polymer is obtained by copolymerization of said monomer with additional compatible ethylenically-unsaturated comonomers.

4. The process according to claim 3 for preparing a shaped article wherein said copolymer is obtained by copolymerization of vinyl trifluoroacetate and maleic anhydride.

5. The process according to claim 3 for preparing a shaped article wherein said copolymer is obtained by copolymerization of vinyl trifluoroacetate and vinyl acetate.

6. The process according to claim 2 wherein said hydrogel article comprises in the range of 10 to 95 weight percent of an aqueous liquid.

7. The process according to claim 6 for preparing a hydrogel shaped article.

8. The process according to claim 6 for preparing a hydrogel ophthalmic device.

9. The process according to claim 1, wherein said shaped article is a corneal transplant or corneal implant.

10. The process according to claim 2 for preparing an ophthalmic device.

11. The process according to claim 2 for preparing a contact lens.

12. The process according to claim 11 wherein said polymer is obtained by copolymerization of vinyl trifluoroacetate and vinyl acetate or maleic anhydride.

13. The process according to claim 2 for preparing an intraocular lens.

14. The process according to claim 13 wherein said polymer is obtained by copolymerization of vinyl trifluoroacetate and vinyl acetate or maleic anhydride.

15. The process according to claim 1 wherein said monomer is vinyl trifluoroacetate.

16. The process according to claim 15 wherein said units of vinyl trifluoroacetate are present in an amount of at least 95 weight percent.

17. The process according to claim 1 wherein said monomer is trihaloacetoxyethyl acrylate or trihaloacetoxyethyl methacrylate.

18. The process according to claim 1 wherein said monomer is an isopropyl or n-propyl acrylate or methacrylate ester.

19. The process according to claim 18 wherein said units of isopropyl or n-propyl acrylate or methacrylate ester are present in an amount of at least 50 weight percent.

20. The process according to claim 1 wherein said polymer is obtained by copolymerization of said monomer with additional compatible ethylenically-unsaturated comonomers.

21. The process according to claim 20 wherein said comonomers are vinyl esters or disubstituted ethylenes.

22. The process according to claim 20 wherein said comonomers are (a) vinyl esters, (b) vinyl ethers, or (c) disubstituted ethylenes.

23. The process according to claim 22 wherein said comonomer is a disubstituted ethylene selected from the group consisting of maleic anhydride, dimethyl itaconate, and monoethyl fumarate.

24. The process according to claim 20 wherein said monomer is an acrylate or methacrylate and said comonomer is vinyl acetate, vinyl perfluoro-n-butyrate, vinyl formate, methyl methacrylate, ethyl methacrylate, ethoxyethyl methacrylate, or propyl methacrylate.

25. The process according to claim 20 wherein said monomer is vinyl trifluoroacetate and said comonomer is a vinyl ether.

26. The process according to claim 1 wherein said polymer further comprises units derived from additional compatible ethylenically-unsaturated comonomers.

27. The process according to claim 1 wherein said ethylenically-unsaturated monomer is present in an amount greater than 50 percent by weight.

28. The process according to claim 1 wherein said thermoforming process takes place at a temperature of about 200.degree. C.

29. The process according to claim 1 wherein said nucleophile is a mild base selected from ammonium hydroxide and an organic amine.

30. The process according to claim 1 wherein said shaped article is a corneal transplant or corneal implant.

31. The process according to claim 1 for preparing an ophthalmic device.

32. The process according to claim 1 for preparing a contact lens.

33. The process according to claim 32 wherein said polymer is obtained by copolymerization of vinyl trifluoroacetate and vinyl acetate or maleic anhydride.

34. The process according to claim 1 for preparing an intraocular lens.

35. The process according to claim 34 wherein said polymer is obtained by copolymerization of vinyl trifluoroacetate and vinyl acetate or maleic anhydride.

36. The process according to claim 1 for preparing a shaped article which is a homopolymer or copolymer of vinyl alcohol.

37. The process according to claim 36 for preparing a vinyl alcohol homopolymer shaped article.

38. The process according to claim 37 wherein said shaped article is an ophthalmic device.

39. The process according to claim 38 wherein said ophthalmic device is an intraocular lens.