exv10w3







Exhibit 10.3




STATE OF NORTH CAROLINA




WAKE COUNTY



LEASE MODIFICATION AGREEMENT NO. 1




     THIS LEASE MODIFICATION AGREEMENT NO. 1 (this “Agreement”) is made and entered into as of this
31st day of October, 2008 (the “Execution Date”), by and between Crescent Lakeside, LLC, a North
Carolina limited liability company (“Landlord”), and Cornerstone BioPharma Holdings, Inc., a
Delaware corporation authorized to conduct business in the State of North Carolina (“Tenant”).



WITNESSETH:




     WHEREAS, Landlord and Tenant entered into that certain Lease Agreement dated May 1, 2008 (the
“Lease”), pursuant to which Tenant leased approximately 14,863 square feet of office space
contained in Suite 250 (the “Leased Premises”) of the building known as Crescent Lakeside II and
located at 1255 Crescent Green, Cary, North Carolina 27518 (the “Building”). (The Lease is
incorporated herein by reference in its entirety. Any capitalized term used and not otherwise
defined herein shall have the meaning ascribed to it in the Lease.); and



     WHEREAS, the Term of the Lease set forth in Subsection 2.01(g) of the Lease is seven
(7) years and four (4) months; and



     WHEREAS, the Target Commencement Date and the Target Expiration Date of the Lease were both
set forth in Subsection 2.01(h) of the Lease as December 1, 2008 and March 31, 2016
respectively; and



     WHEREAS, the Leased Premises would have been ready for occupancy on November 1, 2008, had it
not been for Tenant delay in the construction of the Tenant Improvements to the Leased Premises,
and because the delay in completion is the result of Tenant delays, the parties want to document
the completion prior to the receipt of a certificate of occupancy and Tenant’s right to occupy the
Leased Premises; and



     WHEREAS, pursuant to Section 3.01 of the Lease (Term), it is the desire of Landlord
and Tenant to set forth the formal Commencement Date and the actual Expiration Date of the Lease
upon the terms and conditions contained herein (the actual Commencement Date will automatically be
the day after the date that the Leased Premises are deemed substantially complete as defined in the
Lease and evidenced by the receipt of a permanent or temporary certificate of occupancy),



     NOW, THEREFORE, in consideration of the premises, rent, mutual covenants and conditions
contained herein, and other good and valuable consideration, the receipt and sufficiency of which
are hereby acknowledged, Landlord and Tenant further agree as follows:



     1. Term. The Term of the Lease shall be extended for one (1) additional month due to
the one (1) month increase in the abated Base Rent period, Therefore, Subsection 2.01(g) of
the Lease (Term) is hereby amended by changing the number “4” next to the word “Months” to the
number “5” (so that the entire Term of the Lease is seven (7) years and five (5) months).



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     2. Formal Commencement Date and Expiration Date. Effective as of the Execution Date,
Subsection 2.01(h) of the Lease is hereby amended by setting forth the formal Commencement
Date of the Lease as November 1, 2008 (with the actual Commencement Date occurring after
substantial completion and upon the receipt of a certificate of occupancy) and the Expiration Date
of the Lease shall remain as March 31, 2016. Tenant’s right to occupy the Leased Premises shall
not be granted as of the formal Commencement Date, but shall be granted as of the actual
Commencement Date.



     3. Base Rent. Effective as of the formal Commencement Date, Subsection
2.01(d) of the Lease (Base Rent) is hereby amended by substituting the Base Rent chart below
for the Base Rent chart currently set forth in the Lease:



	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	Full	 	 	 	Price Per	 	 	 	 	 	 	 	 
	Month(s)	 	 	 	Square	 	 	 	 	 	Annual (or for	 	 
	of the	 	 	 	Foot, per	 	Square	 	time period	 	Monthly Base
	Term	 	Date(s)	 	annum	 	Feet	 	noted) Base Rent	 	Rent
	Landlord and Tenant specifically acknowledge and agree that the Base Rent set forth below shall be adjusted by Landlord’s obligation
to pay Tenant the Base Rent abatement (defined in Section
4.01)
	1 through 3

	 	11/1/08 through
1/31/09
	 	$	0.00
	 	 	 	14,863	 	 	$	0.00
	 	 	$	0.00
	 
	 

	 	 
	 	
($23.25/SF Base
Rent abated)
	 	 	 	 	 	
($23.25/SF
Base Rent abated)
	 	($23.25/SF Base
Rent abated)

	4 through 15

	 	2/1/09 through 1/31/10
	 	$	23.25	 	 	 	14,863	 	 	$	345,564.72	 	 	$	28,797.06	 
	16 through 27

	 	2/1/10 through 1/31/11
	 	$	23.83	 	 	 	14,863	 	 	$	354,185.28	 	 	$	29,515.44	 
	28 through 39

	 	2/1/11 through 1/31/12
	 	$	24.43	 	 	 	14,863	 	 	$	363,103.08	 	 	$	30,258.59	 
	40 through 51

	 	2/1/12 through 1/31/13
	 	$	25.04	 	 	 	14,863	 	 	$	372,169.56	 	 	$	31,014.13	 
	52 through 63

	 	2/1/13 through 1/31/14
	 	$	25.67	 	 	 	14,863	 	 	$	381,533.16	 	 	$	31,794.43	 
	64 through 75

	 	2/1/14 through 1/31/15
	 	$	26.31	 	 	 	14,863	 	 	$	391,045.56	 	 	$	32,587.13	 
	76 through 87

	 	2/1/15 through 1/31/16
	 	$	26.96	 	 	 	14,863	 	 	$	400,706.52	 	 	$	33,392.21	 
	88 through 89

	 	2/1/16 through 3/31/16
	 	$	27.63	 	 	 	14,863	 	 	$	68,444.12
	 	 	$	34,222.06	 
	 
	 	 
	 	 	 	 	 	 	 	 	 	
(for 2 months)
	 	 	 	 






     4. Affirmation of Lease. Except as expressly modified herein, the original terms and
conditions of the Lease shall remain in full force and effect.



     5. Binding Agreement. Upon execution by Tenant, this Agreement shall be binding upon
Tenant, its legal representatives and successors, and, to the extent assignment may be approved by
Landlord hereunder, Tenant’s assigns. Upon execution by Landlord, this Agreement shall be binding
upon Landlord,



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its legal representatives, successors and assigns. This Agreement shall inure to the benefit
of Landlord and Tenant, and their respective representatives, successors and permitted assigns.



     6. Counterparts. This Agreement may be executed in any number of counterparts, each of
which shall be an original, but all of which taken together shall constitute one and the same
instrument.



     IN WITNESS WHEREOF, the parties hereto, intending to be legally bound, have caused this
Agreement to be executed by their respective duly authorized representatives as of the day and year
first above written.



	 	 	 	 	 	 	 	 	 
	 	 	LANDLORD:	 	 	 	 
	 
	 	 	 	 	 	 	 	 
	 	 	Crescent Lakeside, LLC, a North Carolina limited liability company	 	 
	 
	 	 	 	 	 	 	 	 
	 	 	By:	 	Capital Associates Management, LLC, a North Carolina limited
liability company, Manager	 	 
	 
	 	 	 	 	 	 	 	 
	 

	 	 	 	By:
	 	/s/ Frank P. Baird
 

Frank P. Baird, Delegate Manager
	 	 






	 	 	 	 	 	 	 
	 	 	TENANT:	 	 
	 
	 	 	 	 	 	 
	 	 	Cornerstone BioPharma Holdings, Inc., a Delaware corporation	 	 
	 
	 	 	 	 	 	 
	 

	 	By:
	 	/s/ Chenyqua Baldwin
 

	 	 
	 

	 	Name:
	 	Chenyqua Baldwin
 

	 	 
	 

	 	Title:
	 	VP – Finance	 	 
	 

	 	 	 	 	 	 






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