# REGISTRATION 264-267 Vol.8

# BayerCropScience

July 15,2010
DocumentProcessing Desk(NOTIF) 

## RegistrationDivision (7505P) Office ofPesticideProgrmns U.S. Environmental ProtectionAgency OnePotomac Yard (SouthBuilding) 

## 2777 S. Crystal Drive Arlington, VA22202
Attn: Mr. Tony Kish (PM22) 

## Subject: ETHRELbrandEthephonPlantRegulator,EPA Registration. No.264-267 SubmissionofFinalPrintedLabel

Dear Mr. Bazuinand Mr. Kish:
Enclosed withthiscover letter, please find onecopyofthe final printed labelingfor ETHREL brand Ethephon PlantRegulator. This submissionwill 

## satisfythe conditionofregistrationfor as specified inyourletterofJune29, 2010.
A completed EPA form 8570-1 accompanies this cover.
Ifyou 

## have questionsregardingourresponse orrequire additional information, pleasecontactme. Sincerely,

LauraPhelps Regulatory Affairs, Herbicides & 

## PGRs BayerCropScience 2 T. W. AlexanderDIive RTP,NC 27709 office: 919-549-2302 email: laura.phelps@bayercropscience.com 

# A 

# BAYER E R

Bayer CropScience P. O. Box 12014 2. T. W.Alexander Drive Research Triangle Park. NC 27709

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# &EPA Environmental Protection Agency Amendment WII.hington, DC 20460 X 

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t. CompenyJProduct Number 2. EPA Product Menager 3. Propo.ed CI

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### 264-267 M. Tony Kish 

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ETHREL® 

### rand Ethephon PlantRegulator 

### 22 5. Name and Addr

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### 6. Expedited Review. In accordance with FIFRA Section 3(c)(31

BayerCropScience LP Ib)(iI, my product is similar orIdentical In compositionand labeling P. O. Box 

### 12014; 2T. W. AlexanderDr. to: ResearchTrianqle Park, NC 

### 27709 

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Explanation: U.e edditlonel pliO.lsi If nacoaa.ry. IFor .actionIond Section II.)

Afinal printedlabel is submittedas a conditionfor ETHREL brandEthephon PlantRegulatorlabel amendment asstipulated in the Agency'sletterofJune

### 29,2010 (EPA Decision Number

### 043151 1).



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... Unclt':il Aree Codel Laura Phelps Reg.Affairs Specialist

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### imprisonment or both under applicable law. 

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### Laura Phelps July 

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### 2010

. . EPA Form 8570-1 (A.v. 8-941 ProVlouil edition, alII obsolete• WhIt••

### EPA FIIt1 

### Copy lorIglnail v_Uow •AppUcant Copy

## Nar REVIEWED InAccordance wiith PR Notice 82-2 BasedOn Draft LabelingDated 

# ® 

# ETHREl brand 

# Ethephon J<-ciy 

# IS;, dole? 

# Plant Regulator For Commercial OrAgricultural Use Only. Not For Residential Use. For use on Apples, Blackberries, Blueberries, Cantaloupes, Cherries, Grapes, Peppers, Pineapple, Sugarcane, Tobacco, Tomatoes, Walnuts, and forthe removal of Dwarf Mistletoe in Ornamental Conifers and Leafy Mistletoe in Ornamental Deciduous Trees and forthe elimination ofundesirablefruit on Apple, Crabapple, Carob, and Olive trees. ACTIVE INGREDIENT: Ethephon [(2-chloroethyl)phosphonic acid]*

.....................................................................21.7% INERT INGREDIENTS:

.........................................................................................................................................78.3% 

### *Contarns 2 pounds ethephon pergallon. 

## EPA Reg. No. 264·267 EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no enliende la etique!a. busque a alguien para que se la explique a usted en detalle. (!fyou do no! understand the label, find someone to explain it to you in de!ai!.) For MEDICALAnd TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800--334-7577 For PRODUCT USE Information Call1-888-AVENTIS (1-888-283-6847) 

# FIRSTAID
IF IN EYES: 

# • Ho!d eye open and rinse slowly and gentlywilh wafer for 15·20 minu!es. 

# • Remove contact lenses, ifpresen!, afterthe firs! 5 minutes, then con!inue rinsing.


## • Call a poison control cen!erordoctor fortreatment advice. IF SWALLOWED: 

## • Immediately call a pOison con!rol center or doclorfor !reatment advice.


## • Do no! induce vomiting unless told to do so by apoison control center ordoctor.


## • Have person sip aglass ofwafer ifable to swallow.


## • Do not**~ive** 

### anythinQ bymouth to an unconscious person. IFON SKIN OR 

# • Take offcon!aminated clothing. CLOTH!NG: Rinse skin immediately with plenty ofwaterfor 15-20 minutes. 

# • • Call a poison control cen!erordoctor fortreatmen! advice. IF INHALED: 

# • Move person to fresh air, 

# • !f person is not breathing. call 911 or an ambulance, then give artificial respira!ion, preferably mouth-to· mou!h ifpossible. 

# • Cal! a poison control center ordoc!orfor furthertreatment advice. For MEDICAL Emergencies Call24 HoursA Day 1-800..J34-7S77. Have the product container or label with you when callinQ a poison control center ordoctor orooinQ fortrea!ment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use of gastric lavage. No spec.ijlc <lntido!e is lotv&:P!able. All treatments should be based on observed signs and symptoms of dis!ress in the patien!. Overexposwe !e, lT,aterials o!her than this product may have occurred. Vic!ims of severe overexposure by inhalation should be kept under medical observalion for up to 72 "loUr> for c91ayed onset of pulmonary edema. In a vic!im of overexposure by ingestion, careful gas!ric lavage is required due to the. pussibility Of stomach or esophageal perforalion. This material is an acid. butthe use ofalkaline substances to neu!ralize it is contrail')dica!ed.

# PRECAUTIONARY STATEMENTS HAZARDS TO HUMANSAND DOMESTIC ANIMALS DANGER Corrosive. Causes irreversible eye damage. Wearsafetygoggleswhen handling. Harmful if swallowed orabsorbed through skin. Do not get in eyes oron clothing. Avoid contactwith skin. Do not inhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials that are chemical-resistant to this product are listed below. Ifyou want more options, followthe instructions for Category A on an EPA chemical-resistance selection chart. 

### Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene orpolyvinyl chloride, shoes plus socks and protective eyewear. When handlers use closed systems, enclosed cabs, or aircraft in a mannerthat meets the requirements listed in the Worker Protection Standard for agricultural pestiCides {WPSl [40 CFR 170.240 {d} {4-6lL the handler PPE requirements may be reduced or modified as specified in the WPS. Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hotwater. Keep and wash PPE separately from other laundry. 

## User Safety Recommendations Users shouldwash hands before eating, drinking, chewing gum, using tobacco orusing the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into clean clothing. The contaminated clothing should be washed before reuse. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofgloves before removing. 

## ENVIRONMENTAL HAZARDS Do not apply directly to water, orto areas where surface water is presentor to intertidal areas below the mean high water mark. Do not contaminate waterwhen disposing ofequipmentwashwaters. 

# DIRECTIONS FOR USE It is a violation of Federal lawto usethis product in a mannerinconsistentwith its labeling. Do notapply this product in away thatwill contactworkers orother persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulations. Read entire label before using this product. 

# AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers, and restricted-entry intelYals. The requirements in this box only apply to uses ofthis product that are covered by the Worker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical-resistant gloves made ofanywaterproof material such as polyethylene or polyvinyl chloride, chemical resistant footwear plus socks, and goggles orface shield. Foroverhead exposure, chemical-resistant headgear is also required. Notify workers ofthe application bywarning them orally and by posting warning signs atentrance to treated areas.

2

# STORAGEAND DISPOSAL PESTICIDE STORAGE Do not contaminate water, food, orfeed by storage and disposal. 

### PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal ofexcess pesticide, spray mixture, or rinsate is a violation of Federal Law. If these wastes cannot 

### be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe Hazardous Waste representative atthe nearest EPA Regional Office for guidance. Wastes resulting from the use ofthis product may be disposed ofon site or at an approved waste disposal facility. 

### CONTAINER DISPOSAL 

### Rigid, Non-refillable containers smallenoughto shake (Le., with capacities equal to or less than 5 gallons) Non-refillable container. Do not reuse or refill this container. Offer for recycling, ifavailable. Triple rinse or pressure rinse container (or equivalent) promptly afteremptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds afterthe flow begins to drip. Fill the container 

### f/4 full with water and recap. Shake for 10seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 

### fO seconds after the flow begins to drip. Repeat this procedure two moretimes. Then offerfor recycling or reconditioning or puncture and dispose ofin a sanitary landfill. ETHREL 

### ® BRAND ETHEPHON PLANT REGULATOR Promotes earlier, uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increases dormantfruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower inductlon, pineapple maturity concentration, sugarcane flower prevention and biomass increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe from ORNAMENTAL DECIDUOUS TREES. Eliminates undesirable fruit on APPLE, CRABAPPLE, CAROB, and OLIVE trees. 

### GENERAL INFORMATION For local recommendations on rates, spray volumes (gallons ofwater per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, Horticultural Specialist, Bayer CropScience Representative or Farm Advisor for his experience with this product in your area. 

### APPLICATION VOLUMES AND SPRAY COVERAGE Thorough spray coverage is essential to achieve maximum product effectiveness. Spray coverage is affected by choice of equipment, nozzle selection and spray boom setup as well as spray pressure, plantsize and canopy density. For both air and ground applications, it is important to choose an equipment setup that 

### will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will vary with the size and density ofthe plant canopy and the equipment used. In California and Arizona use a volume ofno less than 5gallons per acre for aerialapplicatlons. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do not contaminate water used for irrigatlon ordomestic purposes. Avoid spraydrift to nearby crops as this productwill cause modifications in plant growth. Plant injury or reduced yields will result. Do not plantanother crop within 30 days after treatment. DO NOT MIX ETHREL® WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. Add 

### Yo: to 

### 0/. of the required amount ofwater to the spray tank. Start agitation. Add the required amount of ETHREl® brand Ethephon Plant Regulator. Mix only the amount ofsprayyou expectto use each day. Do not allow mixed solution to stand overnight. Do notuse ETHREL® brand Ethephon Plant Regulatorwith additivesother than recommended on this label. Avoid spills ofconcentrated producton spray equipmentor airplane parts. IMMEDIATELY RINSE ANY SPILLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. IMPORTANT: Do not apply ETHREl ® brand Ethephon Plant Regulatorthrough any type ofirrigation system. Do not use this productfor purposes otherthan those listed on the label. Do notexceed the rate of ETHREL® brand Ethephon Plant Regulator peracre peryear recommended on this label.

3

### SPRAY DRIFT Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift 

### may result in illegal residues orinjuryto adjacent crops and vegetation, in the form ofleafyellowing and defoliation. To avoid spraydrift, DO NOT apply aerially when wind speed is greater than 10 mph orduring periods oftemperature inversions. Use ofJarger droplet size 

### wiU also reduce spray drift. AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management requirements must be followed to avoid off-target movementfrom aerial applications to agricultural field crops. These requirements do not apply to forestry applications, publlc health uses orto applications using dryformulations. 

### 1. The distance ofthe outer most nozzles on the boom must not exceed 

### 3/4 the length ofthe wingspan or rotor. 

### 2. Nozzles must always point backward parallel with the airstream and neverbe pOinted downwards more than 

### 45 degrees. Where states have morestringent regulations, they should be observed. The applicatorshould be familiarwith and take into accountthe information covered in the Aerial Drift Reduction Advisory below: 

### AERIAL DRIFT REDUCTION ADVISORY INFORMATION ON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if applications are made improperly, or under unfavorable environmental conditions (See Wind. Temperature and Humidity, and Temperature Inversions). CONTROLLING DROPLET SIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higherflow rate nozzles instead ofincreasing pressure. Number ofnozzles

- Use the minimum numberofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. Significantdeflection from horizontal will reduce dropletsize and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce largerdroplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 

### 3/4 of the wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEtGHT Applications should not be made at a height greater than 10 feet above the top ofthe target plants unless a greater height is required for aircraftsafety. Making applications atthe lowest heightthatis safe reduces exposure ofdroplets to evaporation and wind. SWATHADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance should increase, with increasing drift potential (higherwind, smallerdrops, etc.). WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift potenllal at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and howthey affect spraydrift. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet evaporation is most severewhen conditions are both hotand dry.

4TEMPERATURE INVERSIONS 

### Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the lightvariable winds common during inversions. Temperature inversions are characterized by increasing temperatureswith altitude and are common on nights with limited cloud cover and lightto no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present. inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under lowwind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. SENSITIVE AREAS 

### The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray deposits will damage acrylic plastics, certain paints, and metals. Rinse thoroughly all exposed acrylic-plastic materials and painted surfaces with a detergent and water within one hour afterexposure to spray deposits.

5

# APPLES

APPLES: A foliar spray of ETHREL ® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples. making harvest by 

### hand or machine easier and more efficient. ETHREL® applied in combination with FRUITONE@ N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruit. Applied to young trees, ETHREL 

### ® will suppress vegetative growth and promote flower bud formation.


### Crop Situation
FRUIT LOOSENING


### 1. EARLY AND MIDSEASON MATURING 

### VARIETIES (varieties maturing 

### with Mclntosh or earlier)

2. LATE MATURING VARIETIES IN THE EASTERN UNITED STATES (varieties maturing later than Mcintosh) PROMOTION OF UNIFORM RIPENING AND COLORING OF RED VARIETIES WITHOUT LOOSENING 

## ETHREL® Pints/Acre



### 2 112

5 Specific Directions Apply 

### a foliar spray to apple trees 7 to 14 days priorto normal anticipated harvest. Use sufficient water for thorough unifonn spray coverage. The type of sprayer used and size of trees will affect volume required. Observe fruit daily as the proper picking period is shorter with ETHREL® treated fruit than untreated fruit. Do not exceed 1.25 pounds aiJA per season.

Apply foliar spray of ETHREL® and a preharvest drop control chemical registered for use on apples such as the product FRUITONE® N. Use the preharvest drop control product according to label directlons. Begin spraying 2 to 3 weeks before normal harvest period and about 1 to 2 weeks before desired harvestdate. 1. EARLY OR 1-4 MIDSEASON Apply as a normal dilute spray using MATURING sufficient water for thorough uniform VARIETIES coverage. Actual volume will depend on (varieties the type of delivery of sprayer used and maturing with size oftrees. Mclntosh or Use the lower rate for apples intended for 

# f-_e_a_"_'e_')C-

___ -t
_____ -\ storage. 2. LATE MATURING VARIETIES (varieties maturing later than Mcintosh) 

### 2-4 Do not exceed 1.25 pounds 

### ailA per season. 

### Remarks
ETHREL ® provides several beneficial responses on apples. Depending on rate and time of application ETHREL ®will: promote fruit loosening, promote uniform ripening and coloring without loosening, promotethinning and return bloom, and increase flower bud development in young trees. Fordesired response, follow specific directions. Treat when air temperatures are between 60" F and 90" F. However, application may be made at 50" F under rising temperature conditions. If daytime temperatures are warm, color response from ETHREL® treatment will be reduced, but ripening and loosening effects will be accelerated. Cool weather may extend the interval between treatment and harvest. Do not allow fruit to become overripe on trees. Fruit intended for fresh market must be checked for quality and maturity. Color alone is not an adequate guide for fruit maturity. Use a pressure gauge or other sultable methods for determining internal maturity. Fruit over-matured when harvested and stored may soften sooner than untreated fruit.
Do not apply ETHREL® to more acreage than can be harvested in 1 to 2 days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of preharvest drop vary according to location and variety, follow directlons on the FRUITONE® N label. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

6

### ETHREL® 

### Crop Situation PintsfAcre THINNING AND 

### RETURN BLOOM

1. MostVarieties 

### 1.5 - 4

2. Difficultto Thin 

### 3·6 Varieties Such as Golden Delicious

INCREASED FLOWER BUD DEVELOPMENT 1. NON-BEARING 

### 2-8 TREES



### 2. BEARING 

### 1f2

- 3 TREES


### Use Limitations 

# APPLES (continued)
Specific Directions
Treat 10to 20 days afterfull bloom. Forgreaterthinning, this product can 

### be mixed with AMID-THIN®W, SEVIN® brand 4F Carbaryl Insecticide, SEVIN® brand 80 WSP Carbaryl Insecticide. SEVIN® brand 80 S Carbaryl Insecticide or SEVIN® brand XLR Plus Carbaryl Insecticide for use on apples in accordance with the most restrictive ofthe AMIDTHIN®W, SEVIN® and ETHREL® label limitations and precautions. No label dosage rates may be exceeded. ETHREL ® cannot be mixed with any productcontaining a label prohibition against such mixing. Consult local extension recommendations. Addition ofa non·ionic surfactant can enhance treatmenteffectiveness. Buffering spray solution to a pH of3 to 5 can improve performancewhere wateris alkaline. Use a sprayvolume sufficientto covertrees thorouqhlv and uniforml Spray trees thoroughly and uniformly to the point of runoff. Use the higher rate on more vigorous trees.
Treat 2 to 4 weeks afterfull bloom.

To help minimize fruit thinning, delay application until 6 weeks after full bloom and afterJune drop. 

### Remarks Regulating cropping from one season to another is a problem. Whenever a high percent of the spurs and lateral buds bloom in a single season severe 

### alternate bearing can develop the following year. To overcome this problem 

# "" ETHREL® 

### or a combination of ETHREL® plus AMID-THIN® W or ETHREL® plus one of the SEVIN® products fisted under Specific Directions applied 7 to 21 days after full bloom. The program to use will depend on the amountofthinning required and the biennial bearing history ofyour orchard. Expect Red Delicious to show a reduction of "type" and fruit size particularly on trees under stress. Use of higher label rates may reduce fruit size.

To increase flower bud development on non-bearing trees apply a foliar spray of ETHREL ® 2 to 4 weeks after bloom. Treatment can result in excessive fruit thinning and reduced fruit size and yield reduction the year of usage. ETHREL® should reduce vegetative growth and increase flowering the following spring. Trees should be large enough to support a crop of apples before treatment to initiate flower buds.

The use of ETHREL ® brand Ethephon Plant Regulator can result in overthinning and reduced fruit size. Avoid double coverage and use on lowvigortrees. Environmental factors can affect thinning and return bloom, it is advisable to obtain experience under your conditions by initially testing only a small percent ofyourtrees each yearwith anyone program. User must consider risk ofexcessive fruit thinning and fruit size reduction when using ETHREL ® brand Ethephon Plant Regulatoron young treesjuststarting to bear. Treatonlyvigorous trees since excessive growth reduction will result in weak trees. For best results a thorough uniform spray is needed. A wetting agentmay improve spraycoverage. Do notgraze orfeed covercrops grown in treated apple orchards. Do not harvest apples treated with ETHREL ® brand Ethephon Plant Regulator soonerthan 7 days after last application. Fruit size reduction may occurwhen used to obtain early maturity, especially iffruit is small attime oftreatment. ETHREL® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruitquality and size. FoRow use rates listed above for labeled uses. Do not exceed 8.0 pints ofthis product (2.0 Ib ethephon) peracre per year.

7

# BLACKBERRIES
BLACKBERRiES IN OREGON AND WASHiNGTON: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator will concentrate maturity and loosen fruit, improving harvesting efficiency while reducing cane injury from mechanical harvest.



### ETHREl® 

### CropSituation Pints/Acre Specific Directions 

### Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity, Use ETHREL ®: 

### t) early in the harvest season to 

### AND apply a foliar spray of ETHREL ® 

### at least 3 reduce the number of pickings or 2) treat later in 

### WASHINGTON days prior to expected harvest when air the harvest season for aonce-overfinal picking. 

### (Cultivars temperatures are between 60"F and gO°F Chehalem 

### and rain is not predicted within 24 hours. Thornless and 

### Use sufficient volume to insure thorough Evergreen) and uniform wettina offoliaae and fruit. 

### Use Limitations

Do notspray more than can be harvested on the third dayfollowing treatmentas considerable fruit may drop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants. Do not harvest blackberries treated with ETHREL® brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Do not exceed 8 pints ofthis product (2 Ib ai ethephon) peracre peryear.


# BLUEBERRIES BLUEBERRIES: A foliar spray of ETHREL® brand Ethephon Plant Regulator concentrates maturity of blueberries for easier and more efficient harvest. A foliar spray ofETHREL® brand Ethephon Plant Regulator will abort black barrenberry (Aronia me/anocatpa) 

### flowers and/orfruit growing in Maine lowbush blueberry fields reducing the numberof undesirable barrenberry fruit harvested with blueberries.

ETHREL® Crop Situation Pints/Acre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foffar spray of ETHREL ® 

### brand To concentrate first harvest, apply ETHREL® OF MATURITY Ethephon Plant Regulator at a rate of 4 to brand Ethephon Plant Regulatorwhen 15 to 20% AND EARLIER 8 pints in 150 to 200 gallons ofwater per of the berries are blue. To concentrate final FRUITCOLORING acre. Use the higher spray volume and harvest, treat after the first or second picking. (Cultivars Bluecrop, rate on large dense foliage bushes or Harvest blueberries 

# " proper maturity when Weymouth, Jersey, when temperatures are cool. Treat when colored, generally 

### ooe 

# '0 two 

### weeks after Rancocas, Rubel, airtemperatures are 60 to 90c> F. treatment. Observe fruit daily as the proper Bluetta, Erliblue, Thorough uniform spray coverage of 

### picking period for optimum internal and external Wolcott, Croatan, foliage and fruit is essential for maximum quality is shorter with ETHREL ® 

### brand Ethephon Murphy, Angola, fruit maturation 

### ,od coloration. To 

### aid Plant Regulator treated fruit than with untreated Morrow, Garden uniform wetting of plants, use a wetting fruit. High temperatures (900 

### F) accelerate fruit Blue, Trifblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 

### tOO gallons or X-77 at 2.0 pints per ETHREL ® 

### treatments may increase fruit with 100 gallons. stems, slightly decrease fruit size, soluble solids and acidity. ETHREL ® 

### may not induce internal rioenina as raoidlv as fruit color. BLACK 

### 4-8 Apply 4 to 8 pints per acre of ETHREL® Use the lower rates ofETHREL ® 

### brand Ethephon BARRENBERRY brand Ethephon Plant Regulator in 100 to Plant Regulator when black barrenberries are CONTROL IN LOW 200 gallons of water per acre for ground between 90 to 100% petal faU and use the higher BUSH sprayers and 10 gallons ofwater per acre rates of ETHREL ® 

### when black barrenberry fruit is BLUEBERRIES IN for aerial application. 1/8to 3/16 inch in diameter. This is generally 7 to MAINE Thorough uniform spray coverage 

### ;$ 10 days after blueberries are in the same stages essential. To aid in uniform wetting of of development. Harvest blueberry fruit when plants, use a wetting agent such as X-77 ripe, generally 6 to 8weeks afterapplication. at0.1% ofthe sprayvolume. 

### Use Limitations

Applications to cultivars otherthan those listed above may cause excessive steminess and/or premature crops. Make no more than one application perseason. Ifused for barrenberry control in Maine, do notmake a second application for blueberry concentration ofmaturity or coloring. Do nottreat blueberry plants underdroughtstress orexcessively high temperatures as defoliation and reduced yield may regult.

# CANTALOUPES
CANTALOUPES IN CALIFORNIA, ARIZONA, AND TEXAS: A foliar spray of ETHREL® brand Elhephon Plant Regulator promotes abscission (Slipping) offruil allowing more efficient and economical harvesting.


### ETHREL® 

### Crop Situation Pints/Acre Specific Directions Remarks CALIFORNIA. 

### 3 Good spray coverage 

### ;s The effect will be faster al higher temperatures. Proper liming of ARIZONA, important 

### foc producing 

### ETHREL ® 

### treatment is 

### critical, but may vary from season to 

### TEXAS uniform abscission. Use 40 

### season. Fruit quality, in terms of soluble solids and flesh color, 

### oc more gallons/acre 

### foc does not improve following treatment. Therefore, ETHREL ®should ground 

### "d 10 oc more nol be used until after fruil has developed marketable levels of gallons/acre 

### foc aerial soluble solids and flesh color. ETHREL® promotes abscission of application. (Aerial immature fruit as well as marketable fruit. Thus, using ETHREL® applications 

## "e only too soon will result in poorly colored fruit with substandard soluble permitted in Texas.) solids. 

## Be prepared 

### 10 harvest Observe treated fields frequenlly and pick fruit when market quality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long will lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary following treatment. Plants with low vigor will not respond properly. with temperature. 

## Be sore Do not plant anothercropwithin 30 days aftertreatment. 

### 10 coordinate your**ha~~s1ting** 

### schedule with 

## Ivour acker/shiooer. 

### Use Limitations

ETHREL® brand Ethephon Plant Regulatorshould not be applied when nighttemperatures are below 50°F. Treat only those fruit that have a fairly uniform fruit set, have vines in good condition. and have fruit with marketable soluble solids and internal flesh color. Do not treatfields where soluble solids are running less than 

### 10%. Do not harvest cantaloupes treated with ETHREL ® 

### brand Ethephon Plant Regulatorsoonerthan 2 days after last application. Do not exceed 3 pints ofthis product (0.75 Ib ethephon) peracre peryear.

9

# CHERRIES Except California CHERRIES: A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator loosens fruit and promotes early uniform ripening. and reduces the shaker force needed to mechanically harvest fruit. These effects are importantfor increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree injury. DO NOT USE ON CHERRIES IN CALIFORNIA. A fall application of ETHREL

### ® to sweetcherries in the Pacific Northwest area increases dormantbud hardiness and delays bloom the following spring. 

### ETHREL® 

### Crop Situation Pints/Acre Specific Directions 

### Remarks TART Dilute Spray Apply 

## a, a dilute 

### spray with sufficient 

### water for CHERRIES 

### 1 thorough, uniform 

### coverage. The optimum spray volume will depend on tree size, planting density and eaui ment used. Concen- Concentrate sprays, generally less than 

### 100 gallons per trate Spray acre, require uniform coverage for optimum response.



### 2/3 to 

### 1

SWEET Dilute Spray App!y 

## a, a dilute spray with sufficient water for Expect 

## a longer treatment to CHERRIES 

### 3 to 

### 4 thorough uniform coverage. Actual volume 

### will depend harvest interval with lower rates. (varieties such as on the type of delivery, sprayer used and size oftrees. Windsor, Use lowrates on the light oryellow-coloredvarieties. Napoleon-Royal Anne, Emperor Francis) Concen- Concentrate sprays, generally less than 

### 100 gallons per trate Spray acre, require uniform coverage for optimum response. 

### 2-3

!NCREASED 

### 3 Treat in first two weeks ofSeptember. A fan application of ETHREL® will DORMANT increase fruit 

### bod hardiness by FRUIT BUD decreasing the chance for winter HARDINESS injury and delaying bloom by 

### 3 to 5 AND DELAYED days which may help avoid frost SPR!NG BLOOM iniury. Treatment of ear!y flowering (SweetCherries varieties may delay bloom to better in the Pacific coincide with pollination from other Northwest) varieties. 

### Use Limitations Notfor use on cherries in California. Apply ETHREL® brand Ethephon Plant Regu!ator in a minimum sprayvolume of50gallons peracre. Do not treattoo early as this can cause early fruit drop with stems attached. Some gummosis ofcherry trees is associated with treatment. High temperatures during andafter application may cause severe gummosis. Do nottreattrees that had severe gummosisthe previous year as tree damagewill result. Do not apply to trees that are of !ow vigor or have experienced severe stress (such as winter injury, drought, or disease), since gummosis will be excessive, particularly when high temperatures and/or drought fo!!ow treatment. !fpossible, irrigate orchards to prevent drought stress resulting in gummosis. Do not harvestcherries treated with ETHREL® soonerthan 7 days after !ast application. At the time ofapplication, all fruit including those inside the tree canopy, should be in stage 3 as indicated by rapid size increase and the presence of ground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and**85~F.** Do not treat when air temperatures exceed 85 Q F. Uniform coverage is important, concentrated sprays associated with erratic application can result in gummosis and tip dieback. Some early !eafyellowing and drop may be noted following application. Slightgummosis and individual fruit size reduction may resultwith fall application bud hardiness treatment. Followuse rates listed above for labeled uses. Do notexceed 

### 4.0 pints ofthis product 

### (1.0 Ib ethephon) per acre peryear.
10

# GRAPES (Only in California and Arizona)
GRAPES (TABLE GRAPES IN CALIFORNIA

### AND ARIZONA): An application of ETHREL

### ® brand Ethephon Plant Regulator promotes early uniform color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga. Queen and Tokay allowing more efficient harvests ofqualityfruit GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL® brand Ethephon Plant Regulator will hasten maturity of Thompson seedless grapes resulting in reduced acids, increased sugars and increased raisin quality,



### Crop Situation
TABLE GRAPES (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)


### Use Limitations Table Grapes ETHREL® 

### PintsfAcre 1/2

- 

### 2

t- 

### 2

1-2 Specific Directions For high lemperature conditions (above 85°F) use lower rates of 

### 112 to 1 pint peracre. Forlow temperature conditions (but above 65"F) use higherrates. Apply in sufficienlwaterto wetvines and fruit clusters uniformly, using conventional ground sprayers. Treatwhen 5 - 30% ofberries showcolor. Treat Tokays when 5 - 15% 

### of berries showcolor. Apply as a foliar spray at 5% berry softening. Treat when 5 - 30% of berries show color. 

### Remarks Harvest fruit at desired maturity and quality as indicated by sugar content, acidity and color. This is generally two weeks or more aftertreatment. Watch treated areas closely and harvest before berries become too dark. For more information regarding local experiences with this producton grapes, consult your 

### Fam> Advisor 

# " Exlension Viticulturist.



### A foliar spray 

### of ETHREL® will hasten maturity 

### of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more information regarding local experience with this product on araoes consult vour Farm Advisoror Extension Viticulturist.

Rates higherthan 1 pintlA may increase the incidence ofcracked fruit and should be used only in areas orduring weather conditions where grapes have been especially hard-to-colorin past seasons. Some berry softening is associated with ETHREL ® brand Ethephon Plant Regulator treatment of some varieties which may limit or influence storage considerations. Do not storeTokays. Do not harvestgrapes trealed wilh ETHREL® brand Ethephon Plant Regulatorsoonerthan 14 days after lastapplication. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) per acre peryear. Raisin Production (Thompson Seedless) Do not apply to grapes underslress from insectdamage ormoisture stress. Observe treated vineyards closely and harvestat proper maturity as determined by sugar acid levels. Do not exceed 2 pints ofthis product(0.5 Ib ethephon) per acre per year.

# PEPPERS
PEPPERS: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator promotes early, uniform ripening and coloring for more efficient packing and handling offruit


### ETHREL® Crop Situation Pints/Acre Specific Directions Remarks 

## PEPPERS 1 1/4

- 

### 4 Thorough coverage is essential. For ground or air Check several field locations to determine application choose equipment and spray volumes 

### crop stage aod degree of maturity. that will insure uniform coverage of foliage and fruit. 

### ETHREL® treatments may reduce total 

### Use the higher rate when cool temperatures are yields 

### if applied too early or there is a lack 

### anticipated (less than 65°F), when plants are of uniform, mature, 

### green fruit resulting 

### growing vigorously or when foliage is dense to from split fruit set or variable soil cultural assure thorough wetting ofall leaves and fruit. practices. Harvest fruit after desired color Use the lower rates with lower spray volumes (1 114 and maturity are attained, generally 14 or to 2 pint rate in 20 gallA) and higher rates with more days aftertreatment. higher volumes (3-4 pints/40 gallA). The 3-4 pint rate in less than 40 gpa may cause foliage burn under hotdryconditions. Apply ETHREL® to bell peppers when 10% of fruit are red and chocolate and to chili and pimento pepper varieties when 10to 30% offruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL ® will not ripen immature, Qreen fruit. 

### Use Limitations

Do not applywhen prolonged average high temperatures of95"F aftertreatment are expected. Do not treat when temperatures exceed 100"F. Applications made under high temperatures will accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60"F. Low temperatures after treatment may reduce or negate the effects of ETHREL®brand Ethephon Plant Regulator. Some yellowing and general aging ofleaves will be noted aftertreatment. Do not harvest peppers treated with ETHREL ® brand Ethephon Plant Regulatorsooner than 5 days after last application. Do not exceed 4 pints ofthis product (1.0 Ib ai ethephon) per acre per year. NOTE: Under certain conditions tank mixtures of ETHREL® brand Ethephon Plant Regulator with desiccants containing sodium chlorate could result in the formation ofhypochlorous acids which on heating will emit toxic chloride fumes.

12CROP AND USE 

### PINEAPPLE 

### FlowerInduction ETHREL®applied to pineapple plants will stimulate uniform initiation offlowering.



### Maturity 

### Concentration ETHREL® 

### application will stimulate uniform shell color development
SUGARCANE Flower Prevention ETHREL®

### application will preventor reduce flowering and pithy tissue formation. Biomass Increase ETHREL® 

### used to preventflowering can also result in increased biomass accumulation and recoverable sugar yield. 

### RATE PER 

### ACRE

2 -4quarts



### 1

### -4quarts

2 pints 

# PINEAPPLE AND SUGARCANE

SPRAY VOLUME



### 100

### to 500

gallA



### 100to 

### 300

gallA

7 gallA minimum 

### APPLICATION TIMING

'Bearing age' about 12 months after planting. Generally about 6 months priorto desired haNest.



### When the first fruit begin to change color. SPECIFIC COMMENTS RESTRICTIONS



### Proper rate will vary with Do notgraze pineapple !ocal growing conditions, forage trealed with varieties, plantation ETHREL® 

### Do notharvest 

### management practices pineapples trealedwith and time of year. Use the ETHREL ® soonerthan 2 

### higher rate where earlier days afterthe last harvest is desired. 

### Apply application. 

### when pineapple foliage is de;. 

### Use a broadcast spray, thoroughly cover both foliage and fruit. Use the higher rate during periods of cool or cloudy weather when normal ripening has slowed.

Just prior 

### to initiation. flower Apply by fixed wing aircraft or helicopter using equipment designed to give uniform coverage. Do not harvestsugarcane treated with ETHREL® 

### soonerthan 2 months after1he last application. Do notgraze sugarcane forage treated with ETHREL®. Actual biomass increase will be affected by the time between treatment and harvest. Consider anticipated recoverable sugars as well as biomass to determine optimum harvest date. For Use in Hawaii Only.

13

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE-CURED): A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, uniform "yellowing" ofmature 

### tobacco. ETHREL® reduces curing time, allowing more efficient use of curing barn space, and increased control over harvest schedules. 

### ETHREL® brand Ethephon Plant Regulator increases the capacity of the curing barn by shortening the curing time and allows adjustments in harvestschedules. ETHREL 

### ®can be used as a directed spray to the bottom or middle portion ofthe tobacco plantoras an over-the-top spray. ETHREL® is not intended or recommended for use on immature tobacco.



### ETHREL® 

### Crop Situation Pints/Acre Specific Directions D!RECTED 

### 4 Use drop nozzles. Choose TG orOC spray tips deSigned to apply 50

- 60 gpa at 35-40 psi and at SPRAY tractor speed of 2-3 mph. Use 2 nozzles per row; one on each side of the row dropped low APPLICATION enough to direct the spray to the leaves to be ripened and harvested. Thorough spray coverage is essential. With a directed spray, be sure to harvest all leaves with 20% or more 

### Iyellowinq. OVER-THE-TOP 

### 4-B Treat only Vllhen leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a tendency to be more rank or when temperatures are lower than normal. Always test spray to determine if the tobacco is mature enough to respond to treatmentwith ETHREL ®. Apply over-the-top ETHREL® spray as a fine mist using three nozzles (one nozzle tip over the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similarto the application pattern ofsystemic sucker control agents. Use a spray pressure of40 to 60 psi.


### USE LIMITATIONS Do not apply ETHREL® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality.
Do not allow the crop to over ripen in the field after using ETHREL ®brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do nottreatbefore anticipated major storm which could prevent harvest and result in crop loss. Do notapply ETHREL®brand Ethephon Plant Regulator ifrain is expected within 6 hours.
Do not harvesttobacco treated with ETHREL ® brand Ethephon Plant Regulator soonerthan 2 days after application. Followuse rates listed above for labeled uses. Do notexceed 8 pints ofthis product (2 Ib ethephon) per acre peryear. 

### APPLICATIONTIMING Successful results with ETHREL ® brand Ethephon Plant Regulator call for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the proper treatmenttiming and the number of leaves per stalk ready for harvest, testspray several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves that fail to yellow in 72 hours are not mature and are not ready for ETHREL®treatment. Wait a few days to permitfurther natural maturing, then make anothertestspray or"maturity" check. Determine acres to treat by first confirming the numberofleaves per plantthatwill color, then use barn capacityto calculate the number ofacres to treat. A test spray can be prepared by mixing 4 teaspoons of ETHREL ® brand Ethephon Plant Regulator in 1 quart ofwater. Apply about 1 ounce to each test plant covering all leaves with a fine mist. ETHREL lIDwill not color immatureleaves. To avoid quality loss and/or possible leafdrop, harvest anyyellowed leaves priorto application. Use lower rates under mostconditions. Limit use ofhigherrates to cool (below65"F atthe time oftreatment) slowripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREL ® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leaves have reached the desired color intensity.

14

### Harvest can commence 48 hours after ETHREL® brand Ethephon Plant Regulator application. To determine harvest timing and avoid quality loss or leafdrop, closely monitortreated crop and weather conditions. 

### CURING ETHREL 

### ® BRAND ETHEPHON PLANT REGULATORTREATED TOBACCO Curing procedures are as much an art as a science and each cure must be judged on the basis oftobacco condition, interval between treatment and harvest, weatherand type of curing facility before prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" and early "drying" stages ofthe leaf. Ethephon treated tobacco will have started the coloring process when harvested, reducing the time required in the coloring phase of curing. Treated tobacco should be dried faster. Iftobacco leaves are green orcontain some green when harvested, it may be necessary to colorthem for afew hours. Ifthe leaves are completely yellow, temperature and ventilation must be adjusted in a manner adequate to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you should follow nOmlal procedures for curing. Since ETHREL®

### treated leaves cure faster, treated and untreated leaves should not be cured together in the same barn.



# TOMATOES
TOMATOES (PROCESSED): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates and concentrates tomato ripening increasing recoverable fruit yield from a once-over harvest. Plant Regulator application starts the normal ripening process earlier and increases the rate of ripening of mature green fruit concentrating maturity. Concentrated maturity enables high recoverable yields of ripe tomatoes in once-over harvest. Early concentrated maturity extends the normal harvest season and helps growers schedule harvestand handling more effectively. TOMATOES (FRESH MARKET IN CALIFORNIA): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates tomato ripening increasing the earlyyields ofmarketable ripe fruit.
ETHREL® Crop Situation Pints/Acre Specific Directions Remarks PROCESS 

### 11/4-3 t14 Apply 1 

### Yo to 3 

### Yo pints per acre of Apply ETHREL® when desired tonnage of fruit has TOMATOES ETHREL® brand Ethephon Plant reached marketable size eod 

### maturity. Check fields Early and Regulator in a minimum of 20 gallons closely for stage and degree of uniform maturity prior to Midseason Crops per acre for ground application and a application. Sample several plants throughout the field to
orWaml minimum of 

## to gallons per acre for detemline proper spray date. Sort, weigh and calculate Conditions aerial application. Apply when 5% to the percentfruit which is red and pink, including breakers. t5% of the fruit in the field are red Fruit size alone is not an adequate indicator. Observe and pink (including breakers) and specific directions to determine treatment stage for your there is sufficient mature green fruitto situation. Walk treated fields frequently to evaluate crop produce the desired tonnage. condition. Maintain normal cultural practice between Under high temperatures (above 85 treatment and harvest. Timely harvest is essential for F), rates as low as t tl4 

### pints/acre maximum return of high quality fruit. Consult processor can be effective. representatives concerning delivery schedules eod 

### Thorough coverage is essential. Foe 

### quotas prior to application ofETHREL ®. 

### ground or air application choose Consult your local Bayer CropScience Representative, equipment and spray volumes that Extension Horticultural Specialist or Farm Advisor for will assure unifoml spray coverage of suggestions on the proper use of ETHREL® 

### when fields foliage eod 

### fruit. Overdosing ITom 

### have variable plant vigor due to differences in soil overlapping swaths or spray nozzle conditions or cultural practices and for rates of fruit patterns can cause severe foliage ripening as affected by temperature, within the rate and injury. If bands are sprayed over the timing limitations shown on the label. row, reduce the amount of ETHREL ® 

### used io 

### proportion to the 

### area actually treated. Observe treated fields closely and harvestfruit at proper maturity.

15

# TOMATOES (continued) 

## ETHREL® Crop Situation Pints/Acre Specific Directions Remarks 

### PROCESS 31/4-6 t/2 

### Apply 3 

### Xi to 6 

### Y:. pints per acre of ETHREL® brand Harvest at 

### proper maturity. 

### TOMATOES Ethephon Plant Regulator in a minimum of 20 gallons of Temperatures above 

### gO°F may Late Season or water per acre 10r ground application and a minimum of 

### 10 cause fruit to ripen sooner whereas 

### Coastal Crops or gallons of water per acre for aerial application, Apply when temperatures below 65° 

### F retard 

### Cool Conditions 5% to 30% of fruit in the field are red and pink (including natural color development and may 

### breakers) and there is sufficient mature green fruit to extend the time between treatment produce the desired 

### tonnage. Maximum 

### response ;s and harvest. achieved when fruit to be treated is 5 to 15% pink and red. Use the higher rate 

### of ETHREL® when nighttime temperatures are cool (below 65°F) or vegetative growth is dense. Thorough coverage is essential. For ground or air application choose equipment and spray volumes that wm assure uni10rm scrav coveraae FRESH MARKET 1 

### 1/4

- 5 Apply ETHREL ® when desired tonnage offruit has reached Check treated fruit frequently and TOMATOES marketable size and maturity, generally 3 to 6 days before harvest at desired maturity. Wheo California desired harvest date. Expect only one harvest from treated programming harvest, spray a areas. different block each day aod Apply 1 

### y.; to 5 pints per acre of ETHREL® brand Ethephon harvest blocks daily in the same Plant Regulator in a minimum of 40 gallons of water per sequence.
acre for ground application and a minimum 01 

### to gallons of water per acre for aerial application. Thorough coverage is essential. For ground or air application choose eqUipment and sprayvolumes thatwill assure uniform spray coverage Use the higher rate and longer preharvest interval on late season crops, when temperatures are cool (generally below 85°F) and foliage is dense. Under high temperatures, rates as low as 1 1/4 pints per acre have been effective while reducing foliage damage particularly on more sensitive varieties" see above. 

### Use Limitations Do not apply before there is sufficient mature green fruit to produce the desired tonnage. ETHREL ® brand Ethephon Plant Regulator will not ripen immature green fruit. Some yellowing and general aging offoliage may be observed 101l0wing treatment. Do not treat plants with poor root systems or growing under stress due to poor soil conditions, drought, disease or insect damage. Treatment of weak plants will result in rapid loss of foliage cover increasing sunburn and sun scald potential, especially under high temperature conditions. Do not treat when sustained temperatures above t05°F are anticipated. Do not treat sensitive varieties during period when temperatures exceed tOO°F. Foliar damage is more severe on certain varieties such as VF 

### to, VF 315, VF 145, 21-4, and 13L. During periods ofhigh temperatures usethe lowerrates on sensitive varieties. Do nottank mixwith sun protection products, sun protection whiteners, spray adjuvants orotheradditives, Do not apply ETHREL ® brand Ethephon Plant Regulatorto more acreage than can be harvested in 2 to 3 days. Do notapply ETHREL ® brand Ethephon Plant Regulatorto varieties known to soften rapidly orshatlerwhen ripe. Do not use on greenhouse tomatoes. Do not harvesttomatoes treated with Ethrel® brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Follow use rates listed above for labeled uses, Do not exceed 6.5 pints ofthis product (1.63 lb ethephon) peracre peryear.

16

# WALNUTS
WALNUTS IN CALIFORNIA:A foliar spray of ETHREL® brand Ethephon Plant Regulatorwill loosen walnuts for increased efficiency of mechanical halY8st, promote earlier halVes!, improve hull removal, and increase recoverable yields from a once-overhalY8St. 

### Crop 

### ETHREL® Specific Directions Situation PintsfAcre Expect best results with spray concentrations of California 

### 3-5 300 to 

### 900 ppm, 

### Refer to ETHREl ® 

### spray preparation 

### chart below. Under low temperatures 

### andfor low humidity conditions 

### use the higher label rates. Expect less time between application and halVest with higher label rates. Forbest results treatwhen air temperatures are between 60°F 

### aod 95°F. Expect reduced effectiveness if above 90°F with low humidity due to spray evaporation. Thorough uniform coverage of walnut hulls is essential 

### to< maximum hull split 

### aod mrt loosening response. Choose eqUipment that provides maximum spray penetration of the entire tree canopy. 

### U,e large air carrier sprayers where tree sizejeopardizes coverage. Orvolute sprayer attachments may help.



### USE LIMITATIONS Treatment priorto packing tissue brown (mature) stage may reduce nut quality. Some leafdrop is associated with treatment. 

### Remarks
Walnuts 

### are mature when the packing tissue between kernel halves completes browning. 

### Collect nut samples from throughout the tree canopywhen determining percent nutmaturity. Advancing HalVest· Apply when 95·100% of the nuts have reached maturity. Inspect frequently 

### aod halVest 

# ., soon 

# ., adequate hullability occurs generally 10-16 days 

### aft", treatment depending on variety and weather conditions. Plan second shake 10-12days afterfirst shake. Once Over HalVest

- Variety, growing conditions and weather affect maturity and the opportunity for once over halVest. Contact a local fieldman or Farm Advisor to determine if once over halVest 

### cao 

### be expected 

### ;0 your situation. Apply (0 mature walnuts 10days prior to expected halVest date. Expect actual halVest to range from 7-12 days aftertreatment.

Do nottreatdiseased, lowvigorormoisturestressed trees as excessive leafdrop may occur. Assure that dosage rates are measured accurately since rates higher than recommended may result in tree injury (such as excessive defoliation, reduced catkin formation and twig dieback). Do not halVestwalnuts treated with ETHREL® soonerthan 5 days afterlast application. Do notexceed 5 pints ofthis product (1.25 Ib ethephon) per acre peryear.

ETHREL®SPRAY PREPARATION CHART Sl;1ray Volume (gallons/acre) ETHREL® Rate 

### 100 200 300 400 PintsfA LbS/A Concentration (ppm) 

### 3 0.75 

### 900 450 300



## --- 4 1.00 

### - 600 400 300 5 1.25


## --- 750 500 375 500



## -

-- 300

17

# MISTLETOE REMOVAL
DWARF AND LEAFY MISTLETOE REMOVAL: A foliar spray of 

### ETHREl 

### ® brand Ethephon Plant Regulator will remove dwarf mistletoe shoots in ornamental conifers and leafy mistletoe from ornamental deciduoustrees.

ETHREL® 

### CropSituation Amount DWARF 

### 2pints MISTLETOE ON 

### per ORNAMENTAL 20 gallons CONIFERS DOUGLAS FIR t pint ORNAMENTALS 

### pee 20 gallons

LEAFY 2 quarts MISTLETOE 

### pee ON 20 gallons ORNAMENTAL DECIDUOUS TREES 

### Specific Directions Remarks 

### Apply as a foliar spray to dwarf Applications made in conjunction with sylvicullural mistletoe 

### shoots before mistletoe mistletoe management 

### will prevent spread of the seed dispersal. 

### Foe effective 

### mistletoe parasite to other parts of the tree and removal. all mistletoe shoots must othertrees. 

### be sprayed to wet. Use of a**non~** 

### Mature needle drop, that normally occurs in the ionic surfactant 

### at recommended fall, may be hastened bythe use ofETHREL 00. rates may increase effectiveness. Treat any mistletoe regrowth before Applications of higher rates on Douglas fir may seed disoersal. result in excessive needle drop. Make applications afterfall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. 

### Foe effective mesquite may be difficult to control with a single removal, all mistletoe shoots must application and retreatment may be necessary. be sprayed to wet. Use of a nonionic surfactant 

### at recommended rates may increase effectiveness. Any mistletoe regrowth should be treated during 

### the labeled application window.


# FRUIT ELIMINATION (Ornamental Use Only)
UNDESIRABLE FRUIT ELIMINATION: A foliar spray of ETHREL® brand Ethephon Plant Regulator will reduce or eliminate undesirable fruit development on apple, crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8 to 12ounces Apply as a foliar spray at the flower Application must be made before fruit set for best CRABAPPLES 

### pee bud to full bloom stage, prior to fruit results. 20 gallons set. Wet foliage thoroughly. Over Do not treat weak trees or trees under stress application of ETHREL® Plant (drought, insect or disease damaged trees) as Do notexceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result. ounces (0.15 oz. leaf drop and/or tree defoliation. Some leaf drop or temporary leaf yellowing may

ai/gallon) per 

### U,e higher rates when application. temperatures are cool. occuraftertreatment.
CAROB 6 ounces Apply as a foliar spray. Wet all Do not use on small red fruited varieties of 

### (Ceratonla siliqua) 

### pee foliage thoroughly. Amount of spray crabapple 

### a, fruit elimination will 

### oot be 20 qallons will depend on tree size. satisfactory.

OllVE* 12ounces 

### (Olea europaea) 

### pee 20 qallons *This recommendation IS not Intended to be used on commerCialfrUit production as a ttllnmng agent.

t8

# TURF

An application of Ethrel slows the growth ofturfgrasses thus reducing the required frequency ofmowing and the volume ofclippings collected.

SiTES 

## RATE APPLICATION 

### SPRAY VOLUME Fairways, Roughs & Commercial 6f1ozl1,QOOsqft Applyto activelygrowing turf. Itwill 0.5-4.0 9als/1,000sq

### ft Turfgrasses, including Bentgrass 

### require 7-10

### days for ETHREl®to (Fairway cui), Kentucky act. Reapplication intervals: Bluegrass, Perennial Ryegrass, 

### Kentucky Bluegrass-7 wks. Tall & Fine Fescue 

### Perennial Ryegrass-7 w1<s. Tall/Fine Fescue-4wks. Bentgrass-4 wks. 

### Use Limitations:

Do not allowentry to treated areas until sprays havedried. For best results, apply with sprayer in sufficientvolume afwaterto provide uniform coverage. ETHREL® is foliarly absorbed. Applyonlyto actively growing turf, underfavorable growing condilions, that is notgoing into a donnancy period. Do nottreatturfgrass with poor root systems or growing under stress due to poorsoil conditions, drought, disease or insectdamage. Do not apply to golfcourse greens. Use ofspreaders/stickers with ETHREL® is not necessary. ETHREL® is an acidicproductand prolonged exposure to spraydeposits will damage acrylic plastlcs, certain paints and metals. Rinse thoroughly all exposed acrylic plastic materials and painted surfaceswith a detergent and waterwithin one hour afterexposure to spray deposits.
Test tankmixes with other products on a small area before using widely.

19

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer of Warranties and limitations of liability before using this product. If terms are notacceptable, return the unopened productcontaineratonce. By using this product, useror buyer acceptsthe following Conditions, Disclaimer ofWarranties and limitations ofliability. CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is impossible to eliminate all risks associated with the use ofthis product. Crop injury, ineffectiveness or other unintended consequences may result because ofsuch factors as weather conditions, presence ofother materials, or the manner of use orapplication, all ofwhich are beyond the control ofBayerCropScience LP. All such risks shall be assumed bythe useror buyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPUED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTALOR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE LP'S ELECTION, THE REPLACEMENT OF PRODUCT.



# NET CONTENTS:

ETHREL is a registered trademark ofBayer.

Produced for



# M'"l BaverCropScience

Ji../ "

BayerCropScience P.O. Box 12014,2T.W. Alexander Drive Research Triangle Park, North Carolina 27709

ETHREL® brand Ethephon Plant Regulator (MASTER) Approved 06/29/10

20

## IR4ethephon 

## GH tomato report Tony Kish to: Cynthia Giles-Parker, Barbara Madden Cc: John Bazuin**--<~~<~~~-~-<~-<~<~~~--~~~** 

### 03/t712009 0

### t:26 PM



### This reportwas completed months ago and Bayershould have provided itto the Statesto supportthe SLNs. Theywill seeka 3.5 ppm toleranceto 

### cover small GH tomatoes. Dan Kunkel says itwas not submitted because theywanted towaitto bundlewith sweet potato, coffee, and filberts. Tony

---- Forwarded byTony Kish/OC/USEPA/US on 

### 03/t7/2009 01 :18 PM

---

From: To: 

### Cc: Date: Subject:



### HiTony, Keith Oorschner <dorschner@AESOP.Rutgers.edu> Tony Kish/DC/USEPA/US@EPA 'Dan Kunkel' <kunkel@AESOP.Rutgers.edu> 

### 03/t6/2009 

### to:3tAM FW: New File Uploaded from IR4.rutgers.edu



### Simplyclick on the below link to download the ethephon/tomatofinal report.
It was great speaking with you this morning. Thanks for all your help. Please let me know ifyou have any questions after reviewing the repot.
Keith
Keith Dorschner, Ph.D. Entomology Program Manager IR-4 

### Project Headquarters Rutgers, The State Universityof NJ 500 College Road East, Suite 20t 

# w Princeton, NJ 08540 Phone 732.932.9575, extension

## 46t5 Fax609.5t4.2612



### http://ir4.rutgers.edu/uploads/00250%20signed%2Epdf

Comments: 

## File(s) 

## will stayonline until 04116109

## UNITED STATESENVIRONMENTALPROTECTIONAGENCY WASHINGTON, D.C. 20460

OFFICE OFCHEMICAL SAFETY AND POLLUTION PREVENTION



## Laura Phelps Bayer CropScience P.O. Box 12014 

# JUN 2 9 2010

2 T.W. Alexander Drive Research Triangle Park, North Carolina 27709

Subject: Ethrel brand Ethephon Plant Regulator EPA Registration No. 264-267 Decision D431S11: Your submission on June 2, 2010 of
an amended label, superseding the amended label 

## submitted on January 27, 2010

Dear Ms. Phelps,
The amended master label referred to above, submitted in connection with registration under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), as amended, is acceptable, provided that you comply with the following conditions.
1. Make the following changes to the label.

a. In the third sentence in the "Specific Directions" column in the table on page 7 (in the specific use directions for apples) change "No label dosage rates should be exceeded." to "No label dosage rates may be exceeded."
b. In the first sentence in the third paragraph in the "Specific Directions"· column in the table on page 16 (in the specific use directions for tomatoes) change "

...a minimum of 40 gallons per acre
... " to "

...a minimum of 40 gallons of water per acre
..." and change "

...a minimum of 10 gallons per acre
..." to "

...a minimum of 10 gallons of water per acre
...".

c. In the first sentence in the first "Specific Directions"- column in the table on specific use directions for tomatoes) change paragraph in the page 16 (in the "

...a minimum of 20

## gallons per acre
..." to "

...a minimum of 20 gallons of water per acre
..." and change "

...a minimum of 10 gallons per acre
..." to "

...a minimum of 10 gallons of water per acre
...".
d. In the second sentence in the first paragraph in the "Specific Directions" colunm in the table on page 17, change "Refer to spray ETHREL® preparation chart below." to "Refer to ETHREL® spray preparation chart below."
2. Submit one copy ·of your final printed labeling before you release the product for shipment.
If you have any questions about this letter, please contact John Bazuin at (703}30S-7381 or bazuin.john@epa.gov.

Attachment: 

# ,

ony Kish roduct Manager (22) Fungicide Branch Registration Division (7S04P)

Master label stamped "ACCEPTED with COMMENTS"

# ® 

# ETHREL brand 

# Ethephon Plant Regulator ForCommercial OrAgricultural Use Only. Not For Residential Use. For use on Apples, Blackberries, Blueberries, Cantaloupes, Cherries, Grapes, Peppers, Pineapple, Sugarcane, Tobacco, Tomatoes, Walnuts, and forthe removal of Dwarf Mistletoe in Ornamental Conifers and Leafy Mistletoe in Ornamental Deciduous Trees and forthe elimination of undesirable fruit on Apple, Crabapple, Carob, and Olivetrees. ACTIVE INGREDIENT: Ethephon [(2-chloroethyl)phosphonic acid]·



### ..............................21.7 % 

### INERT INGREDIENTS:

.............................. ............... .............. 

### ...........78.3% *Contains 2 pounds ethephon per gallon. 

## EPA Reg. No. 264·267 EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en details. (Ifyou do not understand the label, find someone to explain it to you in detail.) 

### For MEDICALAnd TRANSPORTAnON EmergenciesONLYCall 24 HoUrsA Day 1-800-334-7577 ForPRODUCT USE Information Call1-888-AVENTIS \1-888-283.6847) 

# FIRSTAID

IF IN EYES: 

# • Hold eye open and rinse slowly and gentlywith waterfor 15-20 minules. 

# • Remove contact lenses, 

### ifpresent, afterthe first 5 minutes, then continue rinsing. 

# • Call a poison control centerordoctorfortreatment advice. 

### IF SWALLOWED: 

## • Immediately call a poisoncontrol centerordoctor for treatment advice.


## • Do not induce vomiting unless told to do so by a poison control centerordoctor.


## • Have person sip a glass ofwater ifable to swallow.


## • Do notQive anvthina by mouth to an unconscious person. IF ON SKINOR 

# • Take offcontaminated clothing. CLOTHING: 

# • Rinse skin immediately with plenty ofwater for 15-20 minutes. 

# • Can a poison control center ordoctorfor treatment advice. IF INHALED: 

## • Move person to fresh air.


## • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-tomouth ifpossible.


## • Call a poison control centerordoctorfor furthertreatment advice. For MEDICAL Emergencies Call 24 HoursA Day 1-800-334-7577. Have the oroduct containeror labelwith vouwhen callina a ooison control center ordoctor oraoina fortreatment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use of gastric lavage. No speCific antidote IS available. All treatments should be based on observed signs and symptoms of distress in the patient. Overexposure to materials other than this product may have occurred. Victims of severe overexposure by inhalation should be kept under medical observation for up to 72 hours for delayed onset of pulmonary edema. In a victim of overexposure by ingestion, careful gastric lavage is required due to the possibility of stomach or esophageal perforation. This material 

### is an acid, but the use ofalkaline substancesto neutralize it iscontraincl"icated. 

### ACCEl'"I'iIJ) 

### wl!hC(}MME1'ITS hi. 

### EPA 

### Letter Dated. 

# JUN 2 9 2010 UadertboFeden:11wmcddde,**~.ruul~Act** lilA 

### u.:wended, 

### f_**~** 

### peetWde**~tered~!!'AReg.No.**



# ---- -J

# &'-/-Jot,,:7

# PRECAUTIONARY STATEMENTS HAZARDS TO HUMANSAND DOMESTIC ANIMALS DANGER Corrosive. Causes irreversible eye damage. Wearsafety goggles when handling. Harmful 

### ifswallowed orabsorbed through skin. Do not getin eyes oron clothing. Avoid contactwith skin. Do not inhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials that are chemical-resistantto this product are listed below. Ifyou want more options, follow the instructions for Category A 

### on an EPA chemical-resistance selection chart. 

### Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene orpolyvinyl chloride, shoes plus socks and protective eyewear. lfIIhen handlers use closed systems, enclosed cabs, or aircraft in a manner that meets 1he requirements listed in the Worker Protection Standard for agricultural pesticides (WPS) [40 CFR 170.240 (d) (4-6)]. the handler PPE requirements may be reduced or modified as specified in the WPS, Discard clothing and other absorbent materialsthat have beendrenched orheav"dy contam'lnated with this products concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions forwashables, use detergent and hotwater. Keep and wash PPE separately from other laundry. 

## UserSafety Recommendations Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into clean clothing. The contaminated clothing should bewashed before reuse. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofgloves before removing. 

## ENVIRONMENTAL HAZARDS Do not apply directly to water, orto areas where surface water is present or to intertidal areas below the mean high water mark Do not contaminate waterwhen disposing ofequipmentwashwaters, 

# DIRECTIONS FOR USE It is a violation ofFederal 

### Law to usethis product in a manner inconsistentwith 

### its labeling. Do not apply this product in awaythatwll1 contactworkers orother persons, eitherdirectlyor through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulations, Read entire label before using this produc!. 

# AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agriCUltural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers, and restricted-entry intervals. The requirements in this box only apply to uses ofthis product that are covered by the Worker Protection Standard. Do not enter or allowworker entry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact wlth anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chem'lcal-resistant gloves made ofany waterproof material such as polyethylene or polyvinyl chloride, chemical resistant footwear plus socks, and goggles orface shield. For overhead exposure, chemical-resistant headgearis also required. Notifyworkers ofthe application bywarning them orally and by posting warning signs at entrance to treated areas.

2

# STORAGE AND DISPOSAL
PESTICIDE STORAGE Do notcontaminatewater, food, orfeed bystorage and disposal. PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of excess pesflc"lde, spray mixture, or rinsate is a violation of Federal 

### law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe Hazardous Waste representative atthe nearest EPA Regional Office for guidance. Wastes resulting from the use ofthis product may be disposed ofon site oratan approved waste disposal facility. 

### CONTAINER DISPOSAL 

### Rigid,**Non~refi!lable** 

### containers small enoughto shake (Le., with capacities equal to or less than 5 gallons) Non-refillable container. Do not reuse or refill this container. Offer for recycling, ifavailable. Triple rinse or pressure rinse container (or equivalent) promptly afteremptying. Triple rinse as follows: Empty the remaining contents into application equipmentor a mix tank and drain for 10 seconds afterthe flow begins to drip. Fill the container 1/4 full with waterand recap. Shake for 10seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling or reconditioning or puncture and dispose of in asanitary landfill. ETHREL® BRAND ETHEPHON PLANT REGULATOR Promotes earlier, uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increases dormant fruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower induction, pineapple maturity concentration, sugarcane flower prevention and biomass Increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe from ORNAMENTAL DECIDUOUS TREES. Eliminates undesirable fruit on APPLE, CRABAPPLE, CAROB, and OLIVE trees. 

### GENERAL INFORMATION For local recommendations on rates, spray volumes (gallons ofwater per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, Horticultural Specialist, Bayer CropScience Representative or Fann Advisor for his experience with this product in yourarea. 

### APPLICATION VOLUMESAND SPRAY COVERAGE Thorough spray coverage is essential to achieve maximum product effectiveness. Spray coverage is affected by choice of equipment, nozzle selection and spray boom setup as well as spray pressure, plantsize and canopy density. For both airand ground applications, it is important to choose an equipment setup that will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will varywith the size and density ofthe plant canopy and the equipment used. In California and Arizona use a volume ofno lessthan 5gallons peracre foraerial applications. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do not contaminate water used for inigation or domestic purposes. Avoid spray driftto nearby crops as this productwill cause modifications in plantgrowth. Plant injury orreduced yields will result. Do notplantanothercrop within 30 days aftertreatment. DO NOT MIX ETHREL® WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. Add % to 

### % of the required amount ofwater to the spray tank. start agitation. Add the required amount of ETHREL ® brand Ethephon Plant Regulator. Mix only the amountofspray you expectto use each day. Do not allow mixed solution to stand overnight. Do not use ETHREL ®brand Ethephon Plant Regulatorwith additives otherthan recommended on this label. Avoid spills ofconcentrated producton spray equipment or airplane parts. IMMEDIATELY RINSE ANY SPilLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. IMPORTANT: Do not apply ETHREl ® brand Ethephon Plant Regulatorthrough anytype of irrigation system. Do not use this productfor purposes otherthan those listed on the label. Do notexceed the rate of ETHREL® brand Ethephon Plant Regulator per acre peryear recommended on this label.

3

### SPRAY DRIFT Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift may result in illegal residues or injury to adjacentcrops and vegetation, in the form ofleafyellowing and defoliation. To avoid spray drift, DO NOTapply aerially when wind speed is greater than 10 mph or during periods oftemperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFTAT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for considering all these factorswhen making decisions. The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field crops. These requirements do not applyto forestry applications, public health uses orto applications using dry formulations. 1. The distance ofthe outer most nozzles on the boom must not exceed 

### 3/4 the length ofthewingspan or rotor. 2. Nozzles mustalways point backward parallel with the air stream and never be pOinted downwards more than 45 degrees. Where states have more stringent regulations, they should be observed. The applicatorshould be familiarwith and take into accountthe information covered in the Aerial Drift Reduction Advisory below: 

### AERIAL DRIFT REDUCTION ADVISORY INFORMATION ON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and HumiditY, and Temperature Inversions). CONTROLLING DROPLETSIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higher flow rates are needed, use higherflow rate nozzles instead ofincreasing pressure. Numberofnozzles

- Use the minimum numberofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. Signfficant deflection from horizontalwill reduce dropletsize and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce largerdroplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back producethe largestdroplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 

### 3/4 of the wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEIGHT Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required for aircraft safety. Making applications atthe lowest heightthat is safe reduces exposureofdroplets to evaporation and wind. SWATH ADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance should increase, with increasing drift potential (higherwind, smaller drops, etc.). WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and howthey affect spray drift. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet evaporation is most severe when conditions are both hot and dry.

4

### TEMPERATURE INVERSIONS 

### Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatureswith altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified 

### by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. SENSITIVE AREAS 

### The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies ofwater, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray deposits will damage acrylic plastics, certain paints, and metals. Rinse thoroughly all exposed acrylic-plastic materials and painted surlaces wah a detergentand waterwithin one hourafterexposure to spray deposits.

5

# APPLES
APPLES: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples, making harvest by 

### hand or machine easier and more efficient. ETHREL® applied in combination with

### FRUITON~ N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruit Applied to young trees, ETHREL® will suppress vegetative growth and promote flower bud formation.



### Crop Situation FRUIT LOOSENING
1. EARLY AND MIDSEASON MATURING VARIETIES (varieties maturing with Mcintosh or earlier) ETHREL® Pints/Acre



### 2 1/2 Specific Directions Apply a foliar spray to apple trees 7 to 14 days priorto normal anticipated halVest. Use sufficient water for thorough uniform spray coverage. The type ofsprayer used and size of trees will affect volume required. ObselVe fruit daily as the proper picking period is shorter with ETHREL® treated fruit than untreated fruit. Do not exceed t.25 pounds ai/A per season. Remarks ETHREL® provides several beneficial responses 

### on apples. Depending on rate and time of application ETHREL ®will: promote fruit loosening, 

### promote uniform ripening and coloring without loosening. promote thinning and return bloom, and increase flower bud development in young trees. 

### Fordesired response, follow specific directions. Treat when air temperatures are between 60° F and 90° F. However, application may be made at 50° F under rising temperature conditions. If daytime temperatures are warm, color response from ETHREL® 

### treatment will be reduced, but ripening and loosening effects will be accelerated. Cool weather may extend the intelVal between treatment and halVest. 2. LATE 5 Do not allow fruit to become overripe on trees. MATURING Fruit intended for fresh market must be checked VARIETIES IN for quality and maturity. Color alone is not an THE EASTERN adequate guide for fruit maturity. Use a pressure UNITED STATES gauge or other suitable methods for determining (varieties internal maturity. Fruit over-matured when 

# --**-~-----** than McintOsh) untreated fruit.

### ~~~~-+------~--------------~ PROMOTION OF UNIFORM RIPENING AND COLORING OF RED VARIETIES WiTHOUT LOOSENING

1. 

### EARLY OR MIDSEASON MATURING VARIETIES (varieties maturing with 

### 1-4 Apply foliar spray of ETHREL® 

### and a prehalVest drop control chemical registered for use on apples such as the product FRUITONE® N. Use the prehalVest drop control product according to label directions. Begin spraying 2 to 3 weeks before normal halVest period and about 1 to 2 weeks before desired halVestdate. Apply as a normal dilute spray using sufficient water for thorough uniform coverage. Actual volume will depend on the type of delivery of sprayer used and size oftrees. Use the lower rate for apples intended for 

# f---'-'="-----+-----I storage. Mcintosh or earlier) 

### 2. LATE 2 - 4 Do not exceed 1.25 pounds ai/A per MATURING season. VARIETIES (varieties maturing later than Mcintosh) Do not apply ETHREL® to more acreage than can be halVested in 1to 2 days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of prehalVest drop vary according to location and variety, follow directions on the FRUITONE@ N label. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

6

### ETHREL® Crop Situation Pints/Acre THINNlNG AND RETURN BLOOM

1. MostVarieties 

### 1.5 - 4

2. Difficultto Thin 

### 3-6 Varieties Such as Golden Delicious

INCREASED FLOWER BUD DEVELOPMENT 

### 1. NON-BEARING 

### 2-8 TREES



### 2. BEARING 

### 112 -3 TREES


### Use Limitations 

# APPLES (continued)
SpecificDirections
Treat 10to 20 days afterfull bloom. Forgreaterthinning, this productcan be mixed with**AMID~THIN®** W, SEVIN® brand 4F Carbaryl Insecticide, SEVIN@brand80WSP Carbaryl Insecticide, SEVIN@brand 80 S Carbaryl Insecticide or SEVlN® brand XLR Plus Carbaryl Insecticide for use on apples in accordancewith the most restrictive oftheAMIDTHIN® W, SEVIN®and ETHREL® label limitations and precautions. No label dosage rates should be exceeded. ETHREL ® cannot be mixedwith any productcontaining a label prohibition againstsuch mixing. Consult local extension recommendations. Addition ofa non-ionicsurtactant can enhancetreatmenteffectiveness. Buffering spray solution to a pH of3 to 5 can improve performance where water is alkaline. Use a spray volume sufficientto covertrees thorouqhlv and unifonnlv. Spray trees thoroughly and uniformly to the point of runoff. Use the higher rate on more vigorous trees.
Treat 2 to 4 weeks afterfull bloom.

To help minimize fruit thinning, delay application until 6 weeks after full bloom and after June droc. Remarks Regulating cropping from one season to another is 

### a problem. Whenever a high percent of the spurs and lateral buds bloom in a single season severe alternate bearing can develop the following year. 

### To overcome this problem use 

### ETHREL® 

### or a combination of ETHREL® plus AMID-THIN® W or ETHREl ® 

### plus one of the SEVIN® products 

### listed under Specific Directions applied 7 to 21 days after full bloom. The program to use will depend on the amountofthinning required and the biennial bearing history ofyourorchard. Expect Red Delicious to show a reduction of "type" and fruit size particularly on trees understress. Use ofhigher label rates may reduce fruit size.

To increase flower bud developmenton non-bearing trees apply a foliar spray of ETHREL® 2 to 4 weeks afterbloom. Treatment can result in excessive fruit thinning and reduced fruit size and yield reduction the year of usage. ETHREL ® should reduce vegetative growth and increase flowering the following spring. Trees should be large enough to support a crop of apples beforetreatmentto initiate flower buds.

The use ofETHREL ® brand Ethephon Plant Regulator can result in overthinning and reduced fruit size. Avoid double coverage and use on lowvigortrees. Environmental factors can affect thinning and return bloom, it is advisable to obtain experience under your conditions by initially testing only a small percentofyourtrees each yearwith anyone program. User must consider risk ofexcessive fruit thinning and fruit size reduction when using ETHREL® brand Ethephon Plant Regulator on young treesjust starting to bear. Treatonlyvigorous trees since excessive growth reduction will result in weaktrees. For best results athorough uniform spray is needed. A wetting agent may improve spray coverage. Do notgraze or feed cover crops grown in treated apple orchards, Do not harvest apples treated with ETHREL ® brand Ethephon Plant Regulator soonerthan 7 days afterlastapplication. Fruitsize reduction mayoccurwhen used to obtain early maturity, especially iffruit is small attime oftreatment. ETHREL ® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruit qualityand size. Follow use rates listed above for labeled uses. Do notexceed 

### B.O pints ofthis product (2.0 Ib ethephon) per acre peryear.

7

# BLACKBERRIES
BLACKBERRIES IN OREGON AND WASHINGTON: A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator will concentrate maturityand loosen fruit, improving harvesting efficiencywhile reducing cane injuryfrom mechanical harvest.



### ETHREL® 

### Crop Situation PintsfAcre 

### Specific Direcflons Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity, Use ETHREL®: 1) early in the harvest season to 

## AND apply a foliar spray of ETHREL® 

### at least 3 reduce the number of pickings or 2) treat later in WASHINGTON 

### days prior to expected harvest when air the harvest season for a once-overfinal picking. (Cultivars temperatures are between 60°F and gO°F Chehalem and rain is notpredicted within 24 hours. Thornless and 

### Use sufficient volume to insure thorough Evergreen) and uniform wettinq offoliaqe and fruit 

### Use Limitations

Do not spray more than can 

### be harvested on the third dayfollowing treatmentas considerable fruit may drop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants. Do not harvest blackberries treated with ETHREL® brand Ethephon Plant Regulatorsooner than 3days after last application. Do not exceed 8 pints ofthis product (21b aiethephon) per acre per year.


# BLUEBERRIES BLUEBERRIES: A fOliar spray of ETHRELlll brand Ethephon Plant Regulator concentrates maturity ofblueberries fOr easier and more efficient harvest. A fOliar spray of ETHREL ® brand Ethephon Plant Regulatorwill abort black barrenberry (Aronia rnelanocarpa) flowers and/orfruit growing in Maine lowbush blueberryfields reducing the numberof undesirable barrenberryfruit harvested with blueberries.

ETHREL® Crop Situation PintsfAcre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foliar spray of ETHREL® brand To concentrate first harvest, apply ETHREL® OF MATURITY Ethephon Plant Regulator at a rate of4 to brand Ethephon Plant Regulatorwhen 15 to 20% AND EARLIER 8 pints in 150 to 200 gallons ofwater per of the berries are blue. To concentrate final FRUIT COLORING acre. Use the higher spray volume and harvest, treat after the first or second picking. (Cu1tivars Bluecrop, rate on large dense foliage bushes or Harvest blueberries 

### ,I proper maturity when Weymouth, Jersey, when temperatures are cool. Treat when colored, generally 

### o,e 10 

### two weeks after Rancocas, Rubel, air temperatures are 60 to 90" F. treatment. Observe fruit daily 

# " Ihe proper Bluetta, Erliblue, Thorough uniform spray coverage 

### of picking period for optimum internal and external Wolcott, Croatan, foliage and fruit is essential for maximum quality is shorter with ETHREL® brand Ethephon Murphy, Angola, fruit maturation 

### "d coloration. To aid Plant Regulator treated fruit than with untreated Morrow, Garden unifOrm wetting of plants, use a wetting fruit. High temperatures (90 0 F) accelerate fruit Blue, Trifblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 100 gallons or X-77 at 2.0 pints per ETHREL® treatments may increase fruit with 100 gallons. stems, slightly decrease fruit size, soluble solids and acidity. ETHRELlll may not induce internal rioenina as rapidly as fruit color. BLACK 

### 4-8 Apply 4 to 8 pints per acre of ETHREL® Use the lower rates ofETHREL® brand Ethephon BARRENBERRY brand Ethephon Plant Regulator in 100 to Plant Regulator when black barrenberries are CONTROL IN LOW 200 gallons of water per acre for ground bet.veen 90 to 100% petal fall and use the higher BUSH sprayers and 10 gallons ofwater per acre rates of ETHREL ® when black barrenberryfruit is BLUEBERRIES IN fOr aerial application. H8 to 

### 3116 inch in diameter. This is generally 7to MAINE Thorough uniform spray coverage 

### ;s 10 days after blueberries are in the same stages essential. To aid in uniform wetting of of development. Harvest blueberry fruit when plants, use a wetting agent such as X-77 ripe, generally 6 to 8weeks afterapplication. at 0.1% ofthe spray'volume. 

### Use Limitations

Applications to cultivars otherthan those listed above may cause excessive steminess andlor premature crops. Make no more than one application per season. Ifused for barrenberry control in Maine, do not make a second application for blueberry concentration ofmaturity orcoloring. Do nottreat blueberry plants underdroughtstress or excessively high temperatures as defonation and reduced yield may reRult.

# CANTALOUPES
CANTALOUPES IN CALIFORNIA, ARIZONA, 

### AND TEXAS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes abscission (slipping) offruit allowing more efficient and economical harvesting.


### ETHREl® Crop Situation Pints/Acre Specific Directions Remarks CALIFORNIA, 

### 3 Good spray coverage is The effect will be faster at higher temperatures. Proper timing of ARIZONA, important for producing 

### ETHREL® treatment is critical, but may vary from season to TEXAS uniform abscission. Use 40 season. Fruit qual'lty, in terms of soluble solids and flesh color, or more 

### gallons/acre for does not improve following treatment. Therefore, ETHREL ®should ground 

## "d 10 or 

### more not be used until after fruit has developed marketable levels of gallons/acre for 

### aerial soluble solids and flesh color. ETHREL® promotes abscission of application. (Aerial immature fruit as well as marketable fruit. Thus, using ETHREL® applications are only too soon will result in poorly colored fruit with substandard soluble permitted in Texas.) solids. Be prepared to harvest Observe treated fields frequently and pick fruitwhen market quality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long will lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary following treatment. Plants with low vigorwill not respond properly. with temperature. Be sure Do not plant anothercrop within 30 days aftertreatment. to coordinate your harvesting schedule 

### with vour packer/shipper. 

### Use Limitations

ETHREL ® brand Ethephon Plant Regulatorshould not be applied when night temperatures are below60°F. Treat only those fruit that have a fairly uniform fruit set, have vines in good condition, and have fruit with marketable soluble solids and internal flesh color. Do nottreatfieldswhere soluble solids are running less than 10%. Do not harvest cantaloupes treated with ETHREL® brand Ethephon Plant Regulatorsoonerthan 2 days afterlastapplication. Do notexceed 3 pints ofthis product (0.75Ib ethephon) per acre peryear.

9

# CHERRIES Except California CHERRIES: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator loosens fruit and promotes early uniform ripening, and reduces the shakerforce needed to mechanically harvestfruit. These effects are important for increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree injury. DO NOT USE ON CHERRIES IN CALIFORNIA. A fall appfication of ETHREL® to sweet cherries in the Pacific Northwestarea increases dormantbud hardiness and delays bloom the farrowing spring. 

### ETHREL® CropSituation Pints/Acre 

### Specific Directions Remarks 

## TART Dilute Spray 

### Apply 

### as a dilute 

### spray with 

### sufficient water 

### foc CHERRIES 

### 1 thorough, 

### uniform coverage. 

### The 

### optimum spray volume will depend on tree size, planting density and equi ment used. Concen- Concentrate sprays, generally less than 100gallons per trate Spray acre, require uniform coverage for optimum response.

2/3 to 1

SWEET Dilute Spray Apply 

### as a dilute spray with sufficient water 

### foc Expect 

### a longer treatment 

### to CHERRIES 3 t04 thorough uniform coverage. Actual volume will depend harvest interval with lowerrates. (varieties such as on the type ofdelivery, sprayer used and size oftrees. Windsor, Use low rates on the light oryellow-colored varieties. Napoleon-Royal Anne, Emperor Francis) Concen- Concentrate sprays, generally less than 100gallons per trate Spray acre, require uniform coverage for optimum response. 

### 2-3

INCREASED 

### 3 Treat In first two weeks ofSeptember. A fall application of ETHREL® will DORMANT increase fruit bod hardiness by FRUIT BUD decreasing the chance for winter HARDINESS injury and delaying bloom by 3 to 5 AND DELAYED days which may help avoid frost SPRING BLOOM injury. Treatment of early flowering (SweetCherries varieties may delay bloom to better in the Pacific coincide with pollination from other Northwest) varieties. 

### Use Limitations Notfor use on cherries in California. Apply ETHREL® brand Ethephon Plant Regulator in a minimum sprayvolume of50 gal10ns per acre. Do nottreattoo earlyasthis can cause earlyfruit drop with stems attached. Some gummosis ofcherrytrees is associated with treatment. High temperatures during and afterapplication may cause severe gummosis. Do nottreattrees that had severe gummosis the previous year as tree damagewill result. Do not apply to trees that are of low vigor or have experienced severe stress (such as winter injury, drought. or disease), since gummosiswill be excessive, particularlywhen high temperatures and/or droughtfOllow treatment. IfpOSSible, irrigate orchards to preventdroughtstress resulting in gummosis. Do not harvest cherries treated with ETHREL ® sooner than 7 days after lastapplication. Atthe time ofapplication, all fruit including those inside the tree canopy, should 

### be in stage 3 as indicated by rapid size increase and the presence of ground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and 85°F. Do not treat when air temperatures exceed 85°F. Uniform coverage is important, concentrated sprays associated with erratic application can result in gummosis and tip dieback. Some early leafyellowing and drop may be noted following application. Slightgummosis and individual fruit size reduction may resultwith fall application bud hardiness treatment. Follow use rates listed above for labeled uses. Do not exceed 4.0 pints ofthis product (t.O Ib ethephon) per acre peryear.
10

# GRAPES (Only in California andArizona)
GRAPES (TABLE GRAPES 

### IN CALIFORNIAAND ARIZONA): An application of ETHREL® brand Ethephon Plant Regulator promotes early uniform color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga, Queen and Tokay allowing more efficient harvests ofqualityfruit. GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator will hasten maturity of Thompson seedless grapes resulting in reduced acids, increased sugars and increased raisin quality.



### Crop Situation 

### TABLE GRAPES (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)


### Use Limitations Table Grapes 

### ETHREL® 

### Pints/Acre

1f2

- 

### 2

1-2

1-2 

### SpecificDirections Forhigh temperature conditions (above 85°F) use lower rates of 1f2 to 1 pintper acre. For low temperature conditions (butabove 65°F) use higher rates. Apply in sufficientwatertowetvines and fruit clusters uniformly, using conventional ground sprayers. Treatwhen 5

- 30% ofberries show color. Treat Tokays when 5

- 15% of berries showcolor. Apply as a foliar spray at 5% berry softening. Treat when 5

- 30% of berries showcolor. 

### Remarks Harvest fruit at desired maturity and quality as indicated by sugar content, acidity and color. This is generally two weeks or more after treatment. Watch treated areas closely and harvest before berries become too dark. For more informalion regarding local experiences with this producton grapes, consult your Farm Advisor 

## oc Extension Viticulturist.



### A foliar spray 

### of ETHREL® will hasten maturity 

### of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more infonnation regarding local experience with th"IS product on 

# Igrapes consultyour Farm Advisoror Extension Viticulturist.

Rates higherthan 1 pintfA may increase the incidence ofcracked fruit and should be used only in areas or during weather conditions where grapes have been especially hard-to-color in pastseasons. Some berry softening is associated with ETHREL® brand Ethephon Plant Regulator treatment of some varieties which may limit or influence storage considerations. Do not store Tokays. Do not harvestgrapes treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 14 days after lastapplication. Do notexceed2 pints ofthis product (0.5 Ib ethephon) per acre peryear. Raisin Production (Thompson Seedless) Do not apply to grapes under stress from insectdamage or moisture stress. Observe treated vineyards closely and harvestat proper maturityas determined by sugar acid levels. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) peracre peryear.



### 11

# PEPPERS
PEPPERS: A foliar spray of

### ETHREl ® brand Ethephon Plant Regulator promotes early, uniform ripening and coloring for more efficient packing and handling offruil.


### ETHREL® Crop Situation Pints/Acre Specific Directions Remarks 

## PEPPERS 1 1/4

- 4 

### Thorough coverage is essential. For ground or air Check several field locations to determine application choose equipment and spray volumes 

### crop 

### stage 

## "d degree of maturity. that will insure uniform coverage of foliage and fruil. 

### ETHREL® treatments 

### m,y reduce total 

### Use the higher rate when cool temperatures are 

### yields if applied too early or there is a lack anticipated (less than 65°F), 

### when plants 

# "e of uniform, mature, 

### green fruil resulting 

### grOwing vigorously or when foliage is dense to from split fruit set or variable soil cultural assure thorough wetting ofall leaves and fruit. practices. Harvest fruit after desired color Use the lower rates with lower spray volumes (1 1/4 and maturity are attained, generally 14 or to 2 pint rate in 20 gal/A) and higher rates with more days aftertreatment. higher volumes (3-4 pints/40 gal/A). The 3-4 pint rate in less than 40 gpa may cause foliage bum under hot dry conditions. Apply ETHREl ® to bell peppers when 10% of fruit are red and chocolate and to chili and pimento peppervarieties when 10to 30% offruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL® will not ripen immature, oreen fruit. 

### Use Limitations

Do not applywhen prolonged average high temperatures of95°F aftertreatment are expected. Do not treat ....nen temperatures exceed 100°F. APplications made under high temperatures wHI accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60°F. Low temperatures after treatment may reduce or negate the effects of ETHREl ®brand Ethephon Plant Regulator. Some yellowing and general aging ofleaveswill be noted aftertreatment. Do not harvest peppers treated with ETHREL® brand Ethephon Plant Regulatorsoonerthan 5 daysafter last application. Do not exceed 4 pints ofthis product (1.0 Ib ai ethephon) peracre peryear. NOTE: Under certain conditions tank mixtures of ETHREl ® brand Ethephon Plant Regulator with desiccants containing sodium chlorate could result in the formation ofhypochlorous acids which on heating will emit toxic chloride fumes.

12CROP AND USE PINEAPPLE RATE PER ACRE



### Flower Induction 2 

### -4 quarts 

### ETHREL® applied to pineapple plants wiH stimulate uniform initiation offlowering.



### Maturity Concentration 

### ETHREl ®application will 

### stimulate uniform shell color development
SUGARCANE Flower Prevention 

### ETHREL®

### application will prevent or reduce flowering and pithy tissue formation. Biomass Increase 

### ETHREL® used to preventflowering can also result in increased biomass accumulation and recoverable sugar yield. ;



### 1

### -4 quarts



### 2 pints 

# PINEAPPLEAND SUGARCANE

SPRAY VOLUME 

### APPLICATION TIMING SPECIFIC COMMENTS



### 100 to 

### 500 'Bearing age' about 12 

### Proper rate will vary with local growing conditions, gallA months after planting.



### 100 to 

### 300

gallA

7gallA minimum I Generally about 6 months ; priorto desired harvest. 

### varieties, plantation 

### management practices and time of year. Use the higher rate where earlier 

### harvest is desired. Apply when pineapple foliage is d<v. 

### When the first fruit begin to change color. Use a broadcast spray, thoroughly cover both foliage and fruit. Use 1he higher rate during periods of cool or cloudy weather when normal ripening has slowed,

Just prior 

### to initiation. flower Apply by fixed wing aircraft or helicopter using equipment designed to give uniform coverage. Actual biomass increase 

### will be affected by the time
I 

### between treatmen1 and

harvest. Consider anticipated recoverable sugars as well as biomass to determine optimum harvestdate. RESTRICTIONS

Do notgraze pineapple forage treated with ETHREl ® Do not harvest pineapples treated with 

### ETHREl ®sooner

### than 2 days afterthe last application.



### Do not harvestsugarcane treated with 

### ETHREL® soonerthan 

### 2 months afterthe last application. Do notgraze sugarcane forage treated with 

### ETHREL®.

For Use in Hawaii Only,

13

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE.CURED): A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, uniform "yellowing" ofmature 

### tobacco. ETHREL® reduces curing time, allowing more efficient use of curing barn space, and increased control over halVes! schedules. 

### ETHREL 

### ® brand Ethephon Plant Regulator increases the capacity of the curing barn by shortening the curing time and allows adjustments in harvestschedules. ETHREL 

### ®can be used as a directed spray to the bottom or middle portion ofthe tobacco plantoras an over-the-top spray. ETHREL® is not intended or recommended for use on immature tobacco.



### ETHREL® Crop Situation Pints/Acre 

### Specific Directions DIRECTED 

### 4 Use drop nozzles. Choose TG or DC spray tips designed to apply50

- 60gpa at35-40 psi and at SPRAY tractor speed of 2-3 mph. Use 2 nozzles per row; one on each side of the row dropped low APPLICATION enough to direct the spray to the leaves to be ripened and halVested. Thorough spray coverage is essential. With a directed spray, be sure to halVest all leaves with 20% or more yeliowinQ. OVER-THE-TOP 

### 4-8 Treat only when leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a tendency to be more rank or when temperatures are lower than normal. Atways test spray to determine if the tobacco is mature enough to respond to treatmentwith ETHREL ®. Apply over-the-top ETHREL® spray as a fine mist using three nozzles (one nozzle tip over the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similar to the aoolication oattem ofsystemic suckercontrol aaents. Use a sorav oressure of40 to 60 osi.


### USE LIMITATIONS Do not apply ETHREL® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality.
Do not allow the crop to over ripen in the field after using ETHREL ® brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do nottreat before anticipated major storm which could prevent halVest and result in crop loss. Do not apply ETHREL® brand Ethephon Plant Regulator ifrain is expected within 6 hours.
Do not halVesttobacco treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 2 days after application. Follow use rates listed above for labeled uses. Do notexceed 8 pints ofthis product (2 Ib ethephon) peracre per year. 

### APPLICATION TIMING Successful results with ETHREL ® brand Ethephon Plant Regulator call for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the proper treatment timing and the number of leaves perstalk ready for halVest, test spray several plants in more than one location in each field and obselVe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves that fail to yeJlow in 72 hours are not mature and are not ready for ETHREL®treatment. Wait a few days to permit further natural maturing, then make anothertest spray or"maturity" check. Determine acres to treat by first confirming the numberofleaves per plantthatwill color, then use barn capacity to calculate the number of acrestotreat. A test spray can be prepared by mixing 4 teaspoons of ETHREL ® brand Ethephon Plant Regulator in 1 quart ofwater. Apply about 1 ounce toeach testplant covering all leaves with a fine mist. ETHREL ® will not color immature leaves. To avoid quality loss and/or possible leafdrop, halVest any yellowed leaves prior to application. Use lower rates under most conditions. Limit use ofhigher rates to cool (below 65"F at the time oftreatment) slow ripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREL ® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leaves have reached the desired color intensity.

14

### Harvest can commence 48 hours after ETHREL®brand Ethephon Plant Regulator application. To determine harvest timing and avoid quality loss or leafdrop, closely monitortreated crop and weatherconditions. 

### CURING ETHREL

### ® BRAND ETHEPHON PLANT REGULATORTREATED TOBACCO Curing procedures are as much an art as a science and each cure must be judged on the basis oftobacco condition, interval between treatment and harvest, weather and type ofcuring faCility before prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must be taken to observe and control the curing process dosely, especially during the late "coloring" and early "drying" stages ofthe leaf. Ethephon treated tobacco will have started the coloring process when harvested, reducing the time required in the coloring phase of curing. Treated tobacco should be dried faster. Iftobacco leaves are green or contain some green when harvested, it may be necessary to colorthem for afew hours. Ifthe leaves are completely yellow, temperature and ventilation must be adjusted in a manneradequate to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you should follow normal procedures for curing. Since ETHREL®

### treated leaves cure faster, treated and untreated leaves should not be cured together in the same barn.


# TOMATOES
TOMATOES (PROCESSED): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates and concentrates tomato ripening increasing recoverable fruit yield from a once-over harvest. Plant Regulator application starts the normal ripening process earlier and increases the rate ofripening of mature green fruit concentrating maturity. Concentrated maturity enables high recoverable yields of ripe tomatoes in once-over harvest. Early concentrated maturity extends the normal harvest season and helps growers schedule harvest and handling more effectively. TOMATOES (FRESH MARKET IN CALIFORNIA): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates tomato ripening increasing the early yields ofmarketable ripe fruit.

Crop Situation PROCESS TOMATOES Early and Midseason Crops orWarm Conditions ETHREL® Pints/Acre 

### 11/4-31/4 Specific Directions Apply t 

### y. to 3 y" 

### pints per acre of ETHREL® brand Ethephon Plant Regulator in a minimum of 20 gallons per acre for ground application and a minimum of 10 gallons per acre for aerial application. Apply when 5% to 15% of the fruit in the field are red and pink (including breakers) and there is sufficient mature green fruit to producethe desired tonnage. Under high temperatures (above 85 F), rates as low as 1 1/4 pints/acre can be effective. Thorough coverage is essential. For ground or air application choose equipment and spray volumes that will assure uniform spray coverage of foliage and fruit. Overdosing from overlapping swaths or spray nozzle pattems can cause severe foliage injury. If bands are sprayed over the row, reduce the amount of ETHREL® used in proportion to the area actuallytreated. Observe treated fields closely and harvestfruit at proper maturity. Remarks Apply ETHREL ® when desired tonnage of fruit has reached marketable size and maturity. Check fields closely for stage and degree of uniform maturity prior to application. Sample several plants throughout the field to determine proper spray date. Sort, weigh and calculate the percent fruit which is red and pink, including breakers. Fruit size alone is not an adequate indicator. Observe specific directions to detellTline treatment stage for your situation. Walk treated fields frequently to evaluate crop condition. Maintain normal cultural practice between treatment and harvest. Timely harvest is essential for maximum return of high quality fruit. Consult processor representatives concerning delivery schedules and quotas priorto application ofETHREL®. 

### Consult your local Bayer CropScience Representative, Extension Horticultural Specialist or Farm Advisor for suggestions on the proper use of ETHREl ® 

### when fields have variable plant vigor due to differences in soil conditions or cultural practices and for rates of fruit ripening as affected by temperature, within the rate and timing limitations shown on the label.

15

# TOMATOES (continued) ETHREL® 

### Crop Situation Pints/Acre Specific Directions Remarks 

## PROCESS 31f4-6t/2 

### Apply 3 

### Y.. to 6 Y; 

### pints per acre of ETHREL® brand HalVes! at proper maturity. TOMATOES Ethephon Plant Regulator in a minimum of 20 gallons per Temperatures above 9O"F may Late Season or 

### acre for ground application and a minimum of 10 gallons cause fruit to ripen sooner whereas Coastal Crops or 

### per acre for aerial application. Apply when 5% to 30% of temperatures below 65° F retard Cool Conditions 

### fruit in the field are red and pink (including breakers) and natural color development and may there is sufficient mature green fruit to produce the desired 

### extend the time between treatment tonnage. Maximum response is achieved when fruit to 

### be and halV8St. treated is 5 to 15% pink and red. Use the higher rate of ETHREL® when nighttime temperatures are cool (below 6S0F) or vegetative growth is dense. Thorough coverage is essential. For ground or air application choose equipment and spray volumes thatwill assure uniform spray coverage FRESH MARKET 1 tf4-S Apply ETHREL®when desired tonnage offruit has reached Check treated fruit frequently and TOMATOES marketable size and maturity, generally 3 to 6 days before halVest at desired maturity. 

### Wheo California desired halVest date. Expect only one harvest from treated programming harvest, spray a areas. different block each day aod Apply 1 X to 5 pints per acre of ETHREL® brand Ethephon halVest blocks daily in the same Plant Regulator in a minimum of 40 gallons per acre for sequence. ground application and a minimum of 10 gallons per acre for aerial application. Thorough coverage is essential. For ground or air application choose equipment and spray volumes thatwill assure uniform spray coverage Use the higher rate and longer preharvest interval on late season crops, when temperatures are cool (generally below 85"F) and foliage is dense. Under high temperatures, rates as low as 1 114 pints per acre have been effective while reducing foliage damage particularly on more sensitive varieties

- see above. 

### Use Limitations Do not apply before there is sufficient mature green fruit to produce the desired tonnage. ETHREL® brand Ethephon Plant Regulator will not ripen immature green fruit. Some yellowing and general aging offoliage may be obselVed following treatment. Do not treat plants with poor root systems or growing under stress due to poor soil cond·lflons, drought, disease or insect damage. Treatment ofweak plants will result in rapid loss of foliage cover increasing sunbum and sun scald potential, especially under high temperature conditions. Do not treatwhen sustained temperatures above 105"F are anticipated. Do not treat sensitive varieties during period when temperatures exceed 100"F. Foliar damage is more severe on certain varieties such as VF 10, VF 315, VF 145, 21-4, and t3L. During periods ofhigh temperatures use the lower rates on sensitive varieties. Do nottank mixwith sun protection products, sun protection whiteners, spray adiuvants orotheradditives. Do notapply ETHREL ® brand Ethephon Plant Regulatorto more acreage than can be halVested in 2 to 3days. Do notapply ETHREL® brand Ethephon Plant Regulatortovarieties known to soften rapidly orshatterwhen ripe. Do not use on greenhouse tomatoes. Do not halVesttomatoes treated with Ethrel® brand Ethephon Plant Regulator soonerthan 3days after last application. Follow use rates listed above for labeled uses. Do notexceed 6.S pints ofthis product (1.63 Ib ethephon) per acre peryear.

16

# WALNUTS
WALNUTS IN CALIFORNIA: A foliarspray of ETHREL 

### ® brand Ethephon Plant Regulatorwill loosen walnuts for increased efficiencyof mechanical harvest, promote earlier halVest, improve hull removal, and increase recoverable yields from a once-over harvest.


### Crop ETHREL® 

### Specific Directions Situation Pints/Acre Expect best results with spray concentrations of California 

### 3-5 300 to 

### 900 ppm. 

### Refer to spray ETHREL® preparation chart below. Under low 

### temperatures and/or low humidity conditions use the higher label rates. Expect less time 

### between application and halVest with higher label rates. For best results treatwhen airtemperatures are between 60"F aod 

### 95°F. Expect reduced effectiveness if above 90°F with low humidity due to spray evaporation. Thorough uniform coverage of walnut hulls is essential 

### foe maximum hull split aod 

### oot loosening response. Choose equipment that provides maximum spray penetration of the entire tree canopy. 

### U,e large air carrier sprayers where tree size jeopardizes coverage. Orvolute sprayer attachments may help.



### USE 

### LIMITATIONS Treatment priorto packing tissue brown (mature) stage may reduce nut quality. Some leafdrop is associated with treatment. Remarks Walnuts are mature when the packing tissue between 

### kernel halves completes browning, 

### Collect nut samples from throughout the tree canopywhen determining percent nut maturity. 

### Advancing HalVest

- Apply when 95-100% ofthe nuts have reached maturity. Inspect frequently aod 

### harvest as soon 

### as adequate hullability occurs generally 10-16 days after treatment depending on variety and weather conditions. Plan second shake 10-12 days afterfirst shake. Once Over HalVest

- Variety, growing conditions and weather affect maturity and the opportunity for once over halVes!. Contact a local fieldman or Farm Advisor to determine if once over halVest can be expected in your situation. Apply to mature walnuts 10 days priorto expected halVest date. Expect actual halVest to range from 7-12 days aftertreatment.

Do not treat diseased, lowvigorormoisturestressed trees as excessive leafdrop may occur, Assure that dosage rates are measured accurately since rates higher than recommended may result in tree injury (such as excessive defoliation, reduced catkin formation and twig dieback). Do not halVestwalnuts treated with ETHREl ® 

### soonerthan 5 days after last application. Do notexceed 5 pints ofthis product (1.25Ib ethephon) peracre peryear.

ETHREL®SPRAY PREPARATION CHART SgrayVolume {gallons/acre} ETHREL® Rate 

### 100 200 300 400 Pints/A lbs/A Concentration (gpm) 

### 3 0,75 

### 900 450 300



## --- 4 1.00



## --- 600 400 300 5 1.25



## --- 750 500 375 500



# ---

--- 300

17

# MISTLETOE REMOVAL
DWARF AND LEAFY 

### MISTLETOE REMOVAL: A foliar spray of ETHREL® brand Ethephon Plan! Regulator will remove dwarf m'lstletoe shoots in ornamental conifers and leafy mistletoe from ornamental deciduous trees.



### ETHREL® Crop Situa.tion 

### Amount 

### DWARF 

### 2 pints MISTLETOE ON 

### per ORNAMENTAL 20 gallons 

### CONIFERS DOUGLAS FIR 

### 1 

### pint ORNAMENTALS per 20 gallons

LEAFY 2 quarts MISTLETOE per 

## ON 20 gallons ORNAMENTAL DECIDUOUS TREES Specific Directions Remarks 

### Apply as a foliar spray to dwarf Applications made in conjunction with sylvicultural mistletoe shoots 

### before mistletoe 

### mistletoe management will prevent spread ofthe ",ed dispersal. 

### For effective 

### mistletoe parasite to other parts of the tree and removal, all mistletoe shoots must othertrees. 

### be sprayed to wet Use of a non- Mature needle drop, that normally occurs in the 

### ionic surfactant at recommended fal!, may be hastened by the use ofETHREL®. rates may increase effectiveness. Applications of higher rates on Douglas fir may Treat any mistletoe regrowth before seed dispersal. result in excessive needle drop. Make applications afterfall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. For effective mesquite may be difficult to control with a single removal, all mistletoe shoots must application and retreatment may be necessary. be sprayed to wet. Use of a nonionic surfactant at recommended rates may increase effectiveness. Any mistletoe regrowth should be treated during the labeled application window.


# FRUIT ELIMINATION (Ornamental Use Only)
UNDESIRABLE FRUIT ELIMINATION; A foliar spray of ETHREL® brand Ethephon Plant Regulator will reduce or eliminate undesirable fruit development on apple, crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8 to 12 ounces Apply as a foliar spray at the flower Application must be made before fruit set for best CRABAPPLES per bud to full bloom stage, prior to fruit results. set. Wet foliage thoroughly. Over Do not treat weak trees or trees under stress 20 gallons application of ETHREL® Plant (drought, insect or disease damaged trees) as Do notexceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result. ounces (0.15 oz. leaf drop and/or tree defoliation. Some leaf drop or temporary leaf yellowing may

ai/gallon) per U,e higher rates whe, aoolication. temperatures are cool. occuraftertreatment. CAROB 6 ounces Apply as a foliar spray. Wet all Do not use 0' 

### small red fruited varieties of (Ceratonia si/iqua) 

### per foliage thoroughly. Amount of spray crabapple a, fruit elimination will oot be 20 aallons will depend on tree size. satisfactory.
OUVE* 12 ounces (O/ea europaea) 

### per 20 gallons *This recommendation is not intended to be used on commercial fruit production as athinning agent.

18

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer ofWarranties and Limitaflons of liability before using this product. Ifterms are not acceptable. return the unopened productcontainerat once. By using this product, user orbuyer accepts the following Conditions, DisclaimerofWarranties and limitations of Liability. CONDITIONS: The directions for use of this product are believed to be adequate and must 

### be followed carefu!!y. However, 

### it is impossible to eliminate

## an risks associated with the use ofthis product. Crop injury, ineffectiveness or other unintended consequences may result because ofsuch factors as weather conditions, presence ofother materials, orthe manner ofuse or application, all ofwhich are beyond the control ofBayerCropScience LP. All such risks shall be assumed by the user or buyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWiSE, THAT EXTEND BEYONO THE STATEMENTS MADE ON THIS LABEl. No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT WiTH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OFTHIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, ORAT BAYER CROPSCIENCE LP'S ELECTION, THE REPLACEMENT OF PRODUCT.



# NET CONTENTS:

ETHREL isa reg'lstered trademark ofBayer.

Produced for



# 4 BayerCropScience

BayerCropScience P.O. Box 12014, 2 T.W. Alexander Drive Research Triangle Park, North Carolina 27709

ETHREL ® brand Ethephon Plant Regulator (Pending) 01/20/10, Resubmitted 

### 06/02/10

20

## Ethephon_ETHREL_264-267 LauraPhelps 

## to: JohnBazuin 06/03/201011:13 AM ShowDetails

HelloMr. Bazuin, Page 1of 1

I have attached the pdffile ofPrasad's original applicationfrom January. I hopethis will work. Ourlabel person is onvacation so 

## I cannot getanelectroniccopy of justthelabel. I alsomade notesonthe hard copy I 

## had. Letmeknowifthis will notdo andIwill see ifthereisanotherpersonwhohasaccessto pending labels. Thanksfor all yourhelp,

BestWishes,

LauraPhelps Regulatory Affairs, Herbicides & 

### PGRs BayerCropScience 2 T. W. AlexanderDrive RTP, NC 27709 

## office: 919·549-2302 mobil:919-352-8075 email: Jaura.pheJps@bayercropscience.com

The information containedin this a-maitis forthe exclusive use ofthe intendedrecipient(s) andmaybe confidential, proprietary. and/orlegally privileged. Inadvertentdisclosure ofthis message does notconslitule a waiverofanyprivilege, Ifyou receive Ihis message in error, Please do nol directlyorindireclly use, print, copy, forward, ordisclose anypartofthis message. Please also detele Ihis e-mailand altcopies andnotify Ihe sender ThankyOu_
Foralternate languages

### please go to h./IpJ&ay-f;,u:J,,($c.la1mer,Q_8Xf;,Gye.Q_com



## file:IIC:IDocuments and**Settings~bazuinlLocal** 

## SettingsITemplnotesFCBCEEI-web2812.htm 6/4/2010

## Ethephon

_ETHREL _264-267 Laura Phelps to: JohnBazuin 

## 06/02/201003:53 PM Cc: 

## BeS Reg Correspondence ShowDetaiis



## Hello Mr. Bazuin, Page I ofI

Thankyoufor talkingwithmeonthephonetoday. Attachedisthe EUIREL label (EPA Reg# 264-267) -onenormal andone withhighlightedchanges. Hopefully capturedare the necessary changes in grammarandwording. I have also correctedthepineapple and sugarcane rate adjustments. Thankyou for finding theerror.

BestWishes,

Laura Phelps RegulatoryAffairs, Herbicides & 

### PGRs BayerCropScience 2 T. 

### W. AlexanderDrive 

## RTP, NC 27709 

## office: 919-549-2302 mobil:919-352-8075 email: laura.phelps@bayercropscicnce.com

The information contained in this e-mail

### is forthe exclusive use ofthe intendedreclpient(s) andmaybe confidential. proprietary. andlorlegally privileged. inadvel1entdisclosure ofthis message does not constitute 

### a waiverofanyprivitege. Ifyou receive this message in error, please do not directlyorindirectlyuse, print, copy, fOlWard, ordisclose anypartofthis message. Please alSo delete this e-maitandall copies andnotifythe sender. Thankyou. Foralternate tanguagespteasego to**http://bayerd(sc!.a.!UJ-,,;J~_Q_ayt'![J_V-';JLC.Q!l]**



## file:IIC:\Docwnents and Settings\jbazuin\Local Settings\Temp\notesFCBCEE\-web4243.htm 

## 6/2/2010

# ® 

# ETHREL brand 

# Ethephon Plant Regulator ForCommercial OrAgricultural Use Only. Not For Residential Use. For use on Apples, Blackberries, Blueberries, Cantaloupes, Cherries, Grapes, Peppers, Pineapple, Sugalrcane, Tobacco, Tomatoes, Walnuts, and forthe removal of Dwarf Mistletoe in Ornamental Conifers and Mistletoe in Ornamental Deciduous Trees and forthe elimination of undesirable fruit on Apple, I 

### I I INERT INGREDIENTS:

. 

### ",78.3% *Contains 2 pounds ethephon pergallon. 

## EPA Reg. No, 264·267 EPA Est. No, 264-PA-01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entlende la etiqueta, busque a alguien para que S8 la explique a usteel en detalle. (Ifyou do not understand the label, find someone to explain 

### ittoyou in detail.) For MEDICALAnd TRANSPORTATION Emergencies ONLY Call 

### 24 Hours A Day 

### 1M800M334M7577


# FIRSTAID

IF IN EYES: 

# • Hold eye open and rinse slowly and gentlywith waterfor 15

### M 20 minutes.


## • Remove contact lenses, ifpresent, afterthe first 5 minutes, then continue rinsing.


## • Call a Doison control centeror doctor for treatment advice. IF SWALLOWED: 

# • Immediately call a poison control center ordoctorfor treatment advice. 

# • Do not induce vomiting unless told to do so by a poison control centerordoctor. 

# • Have person Sip aglass ofwater ifable to swallow. 

# • Do notgive anythinQ by mouth to an unconscious person. IF ON SKIN OR 

## • Take offcontaminated clothing. CLOTHING: 

## • Rinse skin immediatelywith plentyofwaterfor 15-20 minutes. 

# • Call a poison control centerordoctor for treatment advice. IF INHALED: 

# • Move person to fresh air. 

# • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-tomouth ifpossible. 

# • Call a poison control centeror doctorforfurthertreatment advice. For MEDICAL Emergencies Call 

### 24 HoursA Day 1

### M 800M 334M 7577. Havethe product containeror label with you when callina a Doison control centerordoctor or aoina for treatment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use of gastnc lavage. No speCific antidote IS available. All treatments should be based on observea' signs and symptoms of distress ·In the patient. Overexposure to materials other than this product may have occurred. Victims of severe overexposure by inhalation should be kept under medical observation for up to 72 hours for delayed onset of pulmonary edema. In a victim of overexposure by ingestion, careful gastric lavage is required due to the possibility of stomach or esophageal perforation. This material is an acid, but the use ofalkaline substances

### to neutralize it is contraindicated.



# "of 20" 

# oi....te;teJ**1~** 

# 1/2.7/1"_ 

# .""f

# I.l£ PRECAUTIONARY STATEMENTS

# <t"~ HAZARDS TO HUMANS AND DOMESTIC ANIMALS**~DANGER** Corrosive. Causes irreversible eye damage. Wearsafety goggles when handling. Harmful jfswallowed orabsorbed through skin. Do not get in eyes oron clothing. Avoid contactwith skin. Do not inhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials that are chemical-resistant tothis product are listed below. Ifyou want more options, follow the instructions forCategory A on an EPA chemical-resistance selection chart. 

### Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, shoes plus socks and protective eyewear. 

### When handlers use closed systems, enclosed cabs, or aircraft in a mannerthat meets the requirements listed in the Worker Protection Standard for agricultural pesticides (WPS) 140 CFR 170.240 (d) 

### (4-6»), the handler PPE requirements may be reduced or modified as speCified in the WPS. Discard clothing and other absorbent materials that have been drenched or heavilycontaminated with this products concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hotwater. Keep and wash PPE separatelyfrom otherlaundry. 

## UserSafety Recommendations Users shouldwash hands before eating, drinking, chewing gum, using tobacco orusing the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into clean clothing. The contaminated clothing should bewashed before reuse. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofgloves before removing. 

## ENVIRONMENTAL HAZARDS Do not applydirectlyto water, or to areas wttere surface water is present or

### to intertidal areas belowthe mean high water mark. Do not contaminate waterwhen disposing ofequipmentwashwaters. 

# DIRECTIONS FOR USE Itis a violation of Federal Lawto usethis productin a mannerinconsistentwith its labeling. Do not apply this product in a waythatwill contactworkers or other persons, eitherdirectly orthrough drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulations. Read entire label before using this product. 

# AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. 

### It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers, and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do notenter or allowworker entry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical-resistant gloves made of any waterproofmaterial such as polyethylene or polyvinyl chloride, chemical resistant footwear plus socks, and goggles orface shield. For overhead exposure, chemical-resistant headgear is also required. Notifyworkers ofthe application by waming them orally and by posting waming signs atentrance to treated areas.

# STORAGEAND DISPOSAL PESTICIDE STORAGE Do not contaminate water, food, orfeed by storage and disposal. 

### PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture. or rinsate is a violation of Federal Law. 

### If these wastes cannot be disposed of by use according to Jabel instructions, contact your State Pesticide or Environmental Control Agency orthe Hazardous Waste representative atthe nearest EPA Regional Office for guidance, Wastes resulting from the use ofthis product may be disposed ofon site or at an approved waste disposal facility. CONTAINER DISPOSAL 

### Rigid, Non-refillable containers small enoughto shake (I.e., with capacities equal to or less than 5 gallons) Non-refillable container. Do not reuse or refill this container. Offer for recycling, ifavailable. Triple rinse or pressure rinse container (or equivalent) promptly afteremptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds afterthe flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds afterthe flow begins to drip. Repeat this procedure two more times. Then offerfor recycling orreconditioning or puncture and dispose ofin a sanitary landfill. ETHREL 

### ® BRAND

### ETHEPHON~PLANT REGULATOR

-- VV< 0 '-'''''"" 

# .-z.., Promotes earlier, 'uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increasesdormant fruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower induction, pineapple maturity concentration, sugarcane flower prevention and biomass increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe from ORNAMENTAL DECIDUOUS TREES. Eliminates undesirable fruit on APPLE, CRABAPPLE, CAROB, and OLIVE trees. 

### GENERAL INFORMATION For local recommendations on rates, spray volumes (gallons ofwater per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, Horticultural Specialist, Bayer CropScience Representative or Farm Advisor for his experience with this product in yourarea. 

### APPLICATION VOLUMES AND SPRAY COVERAGE Thorough spray coverage is essential to achieve maximum product effectiveness. Spray coverage is affected by choice of equipment, nozzleselection and spray boom setup aswell as spray pressure, plant size and canopy density. For both airand ground applications, it is important to choose an equipment setup that will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will varywith the size and density ofthe plant canopy and the equipment used. In California and Arizona use a volume ofno less than 5 gallons peracre for aerial applications. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do notcontaminatewater used for irrigation ordomestic purposes. Avoid spray driftto nearby crops as this productwill cause modifications in plant growth. Plant injury or reduced yields will result. Do not plantanother crop within 30days aftertreatment. DO NOT MIX ETHREL® WiTH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. Add y" to 

### % of the required amount ofwater to the spray tank. Start agitation. Add the required amount of ETHREL® brand Ethephon Plant Regulator. Mix onlythe amountofspray you expectto use each day. Do not allow mixed solution to stand overn·lght. Do not use ETHREL® brand Ethephon Plant Regulatorwith additives otherthan recommended on this label. Avoid spillS ofconcentrated product on spray equipmentorairplane parts. IMMEDIATELY RINSE ANY SPILLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. IMPORTANT: Do notapply ETHREL ® brand Ethephon Plant Regulatorthrough any type of irrigation system. Do not use th'ls productfor purposes otherthan those l"isted on the label. Do notexceed the rate ofETHREL ® brand Ethephon Plant Regulator per acre per year recommended on this label.

### SPRAY DRIFT**~** 

### Avoid spray drift Do not apply when weather conditions may cause drift. Do not allow this product to drift 

## ovo non-target areas. Drift may result in illegal residues or injuryto adjacentcrops and vegetation. in the form ofleafyellowing and defoliation. To avoid spray drift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods oftemperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFTATTHEAPPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field crops. These requirements do not apply to forestry applications, public health uses orto applications using dry formulations. 1. The distance ofthe outer most nozzles on the boom must notexceed 

### 3/4the length ofthe wingspan or rotor. 2. Nozzles mustalways point backward parallel with the airstream and never be pointed downwards more than 45 degrees. Where states have more stringent regulations, they should be observed. The applicator should be familiarwith and take into accountthe information covered in the Aerial Drift Reduction Advisory below: 

### AERIAL DRIFT REDUCTION ADVISORY INFORMATION ON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift 

### potential, but will not prevent drift if applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and Temperature Inversions). CONTROLLING DROPLET SIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higherflow rate nozzles instead of increasing pressure. Numberofnozzles

- Use the minimum numberof nozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel 

### to the airstream produces larger droplets than other orientations and is the recommended practice. Significant deflection from horizontalwill reduce droplet size and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended applicaflon. With most nozzle types, narrower spray angles produce largerdroplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largestdroplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 

### 3/4 of the wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEIGHT Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required for aircraftsafety. Making applications atthe lowest heightthat is safe reduces exposure ofdroplets to evaporation and wind. SWATHADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adivsting the path of the aircraft upwind. Swath adjustment distance should increase, with increasing drift potential (higherwind, smallerdrops, etc.). WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and how they affect spray drift. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, set up equipment to produce largerdroplets to compensate for evaporation. Droplet evaporation is most severe when conditions are both hot and dry.TEMPERATURE INVERSIONS 

### Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended dropletsto remain in a concentrated cloud. This cloud can move in unpredictabledirections due to the lightvariablewinds common during inversions. Temperature inversions are characterized by increasing temperatureswith altitude and are common on nights with limited doud cover and light to no wind. They begin toform as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. SENSlTlVE AREAS 

### The pesticide should only be 

### applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray deposits will damage acrylic plastics, certain paints, and metals. Rinse thoroughly all exposed acrylic-plastic materials and painted surfaces with a detergent and waterwithin one hour afterexposure to spray deposits.

# APPLES
APPLES: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples, making harvest by 

### hand or machine easier and more efficient. ETHREL

### ® applied in combination with

### FRUITON~ N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruit. Applied to young trees, ETHREL

### ® will suppress vegetative growth and promote flower bud formation.



### Crop Situation FRUIT LOOSENING
1. EARLY AND MIDSEASON MATURING VARIETIES (varieties maturing with Mcintosh or earlier) ETHREL® Pints/Acre

2 1/2 

### Specific Directions Apply a foliar spray to apple trees 

### 7 to 14 days priorto normal anticipated harvest. Use sufficient water for thorough uniform spray coverage. The type ofsprayer used and size of trees will .,affect volume

## re~~i'!~.•

# _.J**~** 

# /**~mebf**

# 8b~7daily?stre'proper

# pickfn~ period is shorter with ETHREL® 

### treated fruit than untreated fruit. Do not exceed 1.25 pounds ai/A per season. Remarks
ETHREL® provides several beneficial responses 

### on apples. Depending on rate and time of application ETHREL ® will: promote fruit loosening, 

### promote uniform ripening and coloring without loosening, promote thinning and return bloom, and increase flower bud development in young trees. 

### Fordesired response, follow specific directions. Treat when air temperatures are between 60" F and 90° F. However, application may be made at 50" F under rising temperature conditions. If daytime temperatures are warm, color response from ETHREL® treatment will be reduced, but ripening and loosening effects will be accelerated. Cool weather may extend the interval between treatment and harvest. 2. LATE Do not allow fruit to become overripe on trees. MATURING Fruit intended for fresh market must be checked VARIETIES IN for quality and maturity. Color alone is not an THE EASTERN adequate guide for fruit maturity. Use a pressure UNITED STATES gauge or other suitable methods for determining (varieties internal maturity. Fruit over-matured when maturing later harvested and stored may soften sooner than

## e----'th~a"o~M"o"'o~t~O~'~hIL__+-----__+---------------__j untreated fruit. PROMOTION OF UNIFORM RIPENING AND COLORING OF RED VARIETIES WITHOUT LOOSENING



# ,. EARLY OR MIDSEASON MATURING VARIETIES (varieties maturing with 1 - 4 

### Apply foliar spray of ETHREL® 

### and a preharvest drop control chemical registered for use on apples such as the product FRUITONE® N. Use the preharvest drop control product according to label directions. Begin spraying 2 to 3 weeks before normal harvest period and about 1 

### to 2 weeks before desired harvest date. Apply as a normal dilute spray using sufficient water for thorough uniform coverage. Actual volume will depend on the type of delivery of sprayer used and size oftrees. Use the lower rate for apples intended for**e---':::::::!.----I------~** 

### storage. Mcintosh or earlier) 

### 2. LATE 

### 2

- 4 Do not exceed 1.25 pounds 

### ailA per MATURING season. VARIETIES (varieties maturing later than Mclnto;h) Do not apply ETHREL®

### to more acreage than can be harvested in 1to 2 days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of preharvest drop vary according to location and variety, follow directions on the FRUITONE® N labe!. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

### Crop Situation 

## ETHREL® Pints/Acre THINNiNG AND RETURN BLOOM



### 1. MostVarieties 

### 1.5-4

2. Difficultto Thin 

### 3-6 Varieties Such as Golden Delicious

INCREASED FLOWER BUD DEVELOPMENT 

### 1. NON-BEARING 

### 2-8 TREES



### 2. BEARING 1/2

- 

### 3 TREES


### Use Limitations 

# APPLES (continued)
Specific Directions Treat 10to 20 days afterfull bloom. Forgreaterthinning, this product can be mixed with AM1O-THIN®W, 

### SEVIN@brand4F Carbaryl 

### insecticide, SEViN<&> brand 80 WSP Carbaryl Insecticide, SEVIN@brand 

### 80 S Carbaryl Insecticide or SEViN<&> brand XlR Plus Carbaryl Insecticide for use on apples in accordance with the most restrictive ofthe**AMID~** THIN®W, SEVIN® and ETHREL ® labellimitatlons**and...Bt~.~i,lUtions.** No label dosage

### rate~E~ exceeded. ETHREL cannot be mixed with anyproduct containing a label prohibition againstsuch mixing. Consult local extension recommendations. Addition ofa non-ionicsurfactant can enhance treatment effectiveness. Buffering spraysolution to a pH of

### 3 to 

### 5 can improve performancewhere wateris alkaline. Use a spray volume sufficientto covertrees thoroughly and uniforml Spray trees thoroughly and uniformly to the point of runoff. Use the higher rate on more vigorous trees.
Treat

### 2 to

### 4 weeks after full bloom.

To help minimize fruit thinning, delay application until 

### 6 weeks after full bloom and afterJunedrop. 

### Remarks Regulating cropping from one season to another is a problem. Whenever a high percent of the spurs and lateral buds bloom in a Single season severe alternate bearing can develop the foDowing year. 

### To overcome this problem 

### use ETHREL® 

### or a combination of ETHREL ® 

### plus AMID-THIN® W 

## or ETHREL® plus one of the SEVIN@ products listed under Specific Directions applied 7 to 21 days after full bloom. The program to use will depend on the amount ofthinning required and the biennial bearing history ofyour orchard. Expect Red Delicious to show a reduction of "type" and fruit size particularly on trees understress.

## ~Of higher label rates may reduce fruit size.

!/VI.

# v"'l

Toincrease flower bud development on non-bearing trees apply a fonar spray of ETHREL® 

### 2 to 

### 4 weeks after bloom. Treatment can result in excessive fruit thinning and reduced fruit size and yield reduction the year of usage. ETHREL® should reduce vegetative growth and increase flowering the following spring. Trees should be large enough to support a crop of apples before treatmentto initiate flower buds.

The use ofETHREL® brand Ethephon Plant Regulatorcan result in overthinning and reduced fruit size. Avoid double coverage and use on lowvigortrees. Environmental factors can affect thinning and return bloom, it is advisable to obtain experience under your conditions by initially testing only a small percent ofyourtrees each yearwith anyone program. User must consider risk ofexcessive fruit thinning and fruit size reduction when using**ETHR.fL~rand** Ethephon Plant Regulatoron young treesjuststarting to bear.
__

### ~~

# M ;- f'-o Vv\ HO 

## V\**~I** Treatonlyvigorous trees since excessive growth reduction will result in weak trees.

- 

### .::J For bestresults a thorough uniform spray is needed. A wetting agent may improve spray coverage. Do notgraze or feed cover crops grown in treated apple orchards. Do not harvest apples treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 7 days after last application. Fruitsize reduction may occurwhen used to obtain early maturity, especially iffruit is small attime oftreatment ETHREL ® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruit quality and size. Follow use rates listed above for labeled uses. Do notexceed 8.0 pints ofthis product (2.0 lb ethephon) per acre per year.

# BLACKBERRIES
BLACKBERRIES IN OREGON AND WASHINGTON; A foliar spray of ETHREl® brand Ethephon Plant Regulator will concentrate maturity and loosen fruit, improving harvesting efficiencywhile reducing cane injury from mechanical harvest. 

## ETHREL® Crop Situation Pints/Acre Specific Directions Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity, Use ETHREl ®: 1) early in the harvest season to 

### AND apply a foliar spray of ETHREL® at least 3 reduce the number of pickings or 2) treat later in WASHINGTON 

### days prior to expected harvest when air the harvest season for a once-overfinal picking. (Cullivars temperatures are between 60°F and gO°F Chehalem and rain is not predicted within 24 hours. Thornless and 

### Use sufficient volume to insure thorough Evergreen) and uniform wetting offoliage and fruit. 

### Use Limitations

Do notspray more than can be harvested on thethird dayfollowing treatmentas considerable fruit may drop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants. Do not harvest blackberries treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Do not exceed 8 pints ofthis product(2 Ib ai ethephon) peracre peryear.


# BLUEBERRIES
BLUEBERRIES: A foliar spray of ETHREL ®brand Ethephon Plant Regulator concentrates maturity of blueberries for easier and more efficient harvest. A foliar spray of ETHREL ®brand Ethephon Plant Regulatorwill abort black barrenberry (Aronia melanocarpa) flowers andlorfruit growing in Maine lowbush blueberry fields reducing the numberofundesirable barrenberryfruit harvested with blueberries. 

### ,""\ ETHREL®

# ~'/ 

# ,.... Crop Situation PlntsfAcre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foliar spray of

# ETHR~~~:and To concentrate first harvest, apply ETHREL® OF MATURITY Ethephon Plant Regulator at a rat of4 to brand Ethephon Plant Regulatorwhen 15 to 20% AND EARLIER 8 pints in 150 to 200 gallons ofwater per of the berries are blue. To concentrate final FRUIT COLORING acre. Use the higher spray volume and harvest, treat after the first or second picking. {Cultivars Bluecrop, rate on large dense foliage bushes or Harvest blueberries at proper maturity when Weymouth, Jersey, when temperatures are cool. Treat when colored, generally 000 to two weeks after Rancocas, Rubel, airtemperatures are60 to 900 F. treatment. Observe fruit daily as the proper Bluetta, Erliblue, Thorough uniform spray coverage of picking period for optimum intemal and external Wolcott, Croatan, foliage and fruit is essential for maximum quality is shorter with ETHREL ® brand Ethephon Murphy, Angola, fruit maturation 

### ood coloration. To aid Plant Regulator treated fruit than with untreated Morrow, Garden uniform wetting of plants, use a wetting fruit. High temperatures (900 F) accelerate fruit Blue, Trilblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 100 gallons or X-77 at 2.0 pints per ETHREL ® treatments may increase fruit with 100gallons. stems, slightly decrease fruit size, soluble solids 

# " '("o)C ;

# ~e.ly

# ';,te)**&t~** and acidity. ETHREL® may not induce internal



# NJ'f rioenina as rapidlv as fruit color. BLACK 

### 4-8 Apply 4 to 8 pints per ac HREL ® Use the lower rates ofETHREL® brand Ethephon BARRENBERRY brand Ethephon Plant Regulator

## ~100 to Plant Regulator when black barrenberries are CONTROL IN LOW 200 gallons of**w~er** acre for ground between 90 to 100% petal fall and use the higher BUSH sprayers and 10 ga s rater per acre rates of ETHREL® when black barrenberry fruit is BLUEBERRIES IN for aerial application.**(~tePldt;iJ** 1/8 to 3/16 inch in diameter. This is generally 7 to MAINE Thorough uniform spray coverage is 10 days after blueberries are in the same stages essential. To aid in uniform wetting of of development. Harvest blueberry fruit when plants, use a wetting agent such as X-77 ripe, generally6 to 8weeks after application. at 0.1 % ofthe sorav·volume. 

### Use Limitations

Applications to cultivars otherthan those listed above maycause excessive steminess and/or premature crops. Make no morethan one application perseason. Ifused for barrenberry control in Maine, do not make a second application for blueberry concentration ofmaturity orcoloring. Do not treat blueberry plants underdroughtstress orexcessively high temperatures as defoliation and reduced yield may reeull.

# CANTALOUPES
CANTALOUPES IN CALlFORNIA, ARIZONA, AND TEXAS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes abscission (slipping) offruitallowing more efficient and economical halV8sting.


## ETHREL® Crop Situation Pints/Acre Specific Directions Remarks CALIFORNIA, 

### 3 Good spray coverage 

### i, The effect will be faster at higher temperatures. Proper timing of ARIZONA, important 

### foe producing 

### ETHREL® treatment is critical, but may vary from season to 

### TEXAS uniform abscission. Use 40 season. Fruit quality, in terms of soluble solids and flesh color, 

### oe more gallons/acre 

### foe does not improve following treatment Therefore, ETHREL® should ground aod 

### 10 

### oe moce not be used until after fruit has developed marketable levels of gallons/acre 

### foe aerial soluble solids and flesh color. ETHREL® promotes abscission of application. (Aerial immature fruit as well as marketable fruit. Thus, using ETHREL ® applications ace only too soon will result in poorly colored fruit with substandard soluble permitted in Texas.) solids. Be prepared 

### to harvest Observe treated fields frequently and pick fruitwhen market quality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long will lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary following treatment. Plants with low vigor will not respond properly. with temperature. Be sure Do not plantanothercrop within 30 days aftertreatment 

### to coordinate your harvesting schedule with ouroacker/shipper. 

### Use Limitations

ETHREL® brand Ethephon Plant Regulatorshould not be applied when nighttemperatures are below**60~F.** Treat only those fruit that have a fairly uniform fruit set, have vines in good condition, and have fruit with marketable soluble solids and internal flesh color. Do not treatfields where soluble solids are running less than 10%. 00 not harvest cantaloupes treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 2 days afterlast application. Do not exceed 3 pints ofthis product (0.75 Ib ethephon) per acre peryeaL

# CHERRIES Except California CHERRIES: A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator loosens fruit and promotes early uniform ripening, and reduces the shakerforce needed to mechanically harvestfruit. These effects are important for increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree iniury. DO NOT USE ON CHERRIES IN CALIFORNIA. A fall application of ETHREL® to sweetcherries in the Pacific Northwest area increasesdormantbud hardiness and delays bloom the following spring. 

## ETHREL® Crop 

### Situation 

### Pints/Acre Specific Directions Remarks 

### TART Dilute Spray 

### Apply 

# " a dilute spray 

### with sufficient water for 

### CHERRIES 1 thorough. uniform coverage. 

### The optimum spray volume will depend on tree size, planting density and equipment used. Concen- Concentrate sprays, generally less than 100gallons per trate Spray acre, require uniform coveragefor optimum response.

2/3 to 1

SWEET Dilute Spray Apply 

## as a dilute spray with sufficient water for Expect 

## a longer treatment to CHERRIES 3 to 4 thorough uniform coverage. Actual volume will depend harvest interval with lower rates. (varieties such as on the type of delivery, sprayer used and size oftrees. Windsor, Use low rates on the light oryellow-colored varieties. Napoleon-Royal Anne, Emperor Francis) Concen- Concentrate sprays, generally less than 100gallons per trate Spray acre, require uniform coverage for optimum response. 

### 2-3

INCREASED 

### 3 Treat in first twoweeks of September. A fall application of ETHREL® will DORMANT increase fruit 

### bud hardiness 

### by FRUIT BUD decreasing the chance for winter HARDINESS injury and delaying bloom by 3 to 5 AND DELAYED days which may help avoid frost SPRING BLOOM injury. Treatment ofearly flowering (SweetCherries varieties may delay bloom to better in the Pacific coincide with pollination from other Northwest) varieties. 

### Use Limitations Notfor use on cherries in California. Apply ETHREL® brand Ethephon Plant Regulator in a minimum sprayvolume of50 gallons per acre. Do not treattoo early as this can cause earlyfruit dropwith stems attached. Somegummosis ofcherry trees is associated with treatment. High temperatures during and after application may cause severe gummosis. Do nottreat trees that had severe gummosis the previous year as tree damagewill result. Do not apply to trees that are of low vigor or have experienced severe stress (such as winter injury, drought, or disease), since gummosiswill be excessive, particularlywhen high temperatures and/ordroughtfOllow treatment. Ifpossible, irrigate orchards to preventdrought stress resulting in gummosis. Do not harvestcherries treated with ETHREL ®sooner than 7 days after lastapplication. At the time ofapplication, all fruit including those inside the tree canopy, should be in stage 3 as indicated by rapid size increase and the presence of ground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and 85 Q F. Do not treat when air temperatures exceed 85 Q F. Uniform coverage is important, concentrated sprays associated with erraticapplication can result in gummosis and tip dieback. Some early leafyellowing and drop maybe noted following application. Slightgummosis and individual fruit size reduction may resultwith fall application bud hardiness treatment. 

# "0+ '2.0 4- Follow use rates listed above for labeled uses. Do not exceed 4.0 pints ofthis product (1.0 Ib ethephon) peracre per year.

### ~~ 

# "f"'je.-'(**ote..{~** - ...

# 10~

# GRAPES (Only in California andArizona)
GRAPES (TABLE GRAPES IN CALIFORNIA AND ARIZONA): An application of ETHREL ® brand Ethephon Plant Regulator promotes early uniform color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga. Queen and Tokay allowing moreefficient harvests ofquality

### fruit. GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator will hasten maturity of Thompson seedless grapes resulting in reduced acids, increased sugars and increased raisin quality

.


### Crop Situation TABLE GRAPES (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)


### Use Limitations Table Grapes ETHREL® 

### Pints/Acre



### 1/2 - 2



### 1-2

1

- 2 

# .s**!l.~~** ,..(\...Specific Directions

# FO[~",M~"litiO", (abov "F) use lower rates of 

### 112 to 1 pin er acre. For low temperature onditions (butabove 65°F) use higher rates. Apply in sufficientwaterto wetvines and fruit clusters uniformly, using conventional ground sprayers. Treatwhen 5 - 30% ofberries showcolor. Treat Tokays when 5 - 15% of berries showcolor. Apply as a foliar spray at 5% berry softening. Treat when 5

- 30% of berries showcolor. 

### Remarks Harvest fruit at desired maturity and quality as indicated by sugar content, acidity and color. This is generally two weeks or more aftertreatment. Watch treated areas closely and harvest before berries become too dark. For more information regarding local experiences with this producton grapes, consult your Farm Advisor oc Extension Viticulturist.



### A foliar spray of ETHREL® will hasten maturity of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more information regarding local experience with this product on araoes consult vour Farm Advisoror Extension Viticulturist.

Rates higherthan 1 pintlA may increase the incidence ofcracked fruit and should be used only in areas or during weather conditions where grapes have been especially hard-to-color in pastseasons. Some berry softening is associated with ETHREL ® brand Ethephon Plant Regulator treatment of some varieties which may limit or influence storage considerations. Do notstore Tokays. Do not harvest grapestreated with ETHREL ® brand Ethephon Plant Regulator soonerthan 14 days afterlast appl"lcation. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) per acre per year. Raisin Production (Thompson Seedless) Do not apply to grapes understress from insectdamage or moisture stress. Observe treated vineyards closely and harvest at proper maturity as determined by sugaracid levels. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) peracre peryear.

# !1~

# PEPPERS
PEPPERS: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator promotes early, uniform ripening and coloring for more efficient packing and handling offruit.



### Crop Situation 

## PEPPERS

Use Limitations 

## ETHREL® Pints/Acre

1 1/4

- 

### 4 

### Specific Directions 

### Thorough coverage is essential. For ground or air application choose equipment and spray volumes that will insure uniform coverage offoliage and fruil. 

### Use the higher rate when cool temperatures are 

### anticipated (leSS than**65~F),** 

### when plants are growing vigorously or when foliage is dense to assurethorough wetting ofall leaves and fruit. Use the lower rates with lower spray volumes (1 

### 1/4 to 

### 2 pint rate in 

### 20 gallA) and higher rates with higher volumes (3-4 pints/40 gallA). The 3-4 pint rate in less than 40 gpa may cause foliage burn under hot dry conditions. Apply ETHREL ® to bell peppers when 10% of fruit are red and chocolate and to chili and pimento pepper varieties when 10 to 30% of fruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL® will not ripen immature, Qreen fruit. 

### Remarks Check several field locations to determine crop stage and degree of maturity. ETHREL® treatments may reduce total yields if applied too early or there is a lack of uniform, mature, green fruit resulting from split fruit set or variable soil cultural practices. Harvest fruit after desired color and maturity are**attaine~enerally** 14 or more days aftertreatment. )

# C~e..{J

Do not applywhen prolonged average high temperatures of95°F aftertreatmentare expected. Do not treat when temperatures exceed 100"F. Applications made under high temperatures will accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60"F. Low temperatures after treatment may reduce or negate the effects of ETHREL ®brand Ethephon Plant Regulator. Some yellowing andgeneral aging ofleaveswill be noted after treatment. Do not harvest peppers treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 5 days after last application. Do not exceed 4 pints ofthis product (1.0 Ib ai ethephon) per acre peryear. NOTE: Under certain conditions tank mixtures of ETHREL® brand Ethephon Plant Regulator with desiccants containing sodium chlorate could resuft in the formation ofhypochlorous acids which on heating will emit toxicchloride fumes.CROP AND 

## USE PINEAPPLE 

### Flower Induction ETHREL®applied to pineapple plants will stimulate unjform initiation offlowering.



### Maturity Concentration ETHREL® application will stimulate unjform shell color development


### SUGARCANE Flower Prevention ETHREL®

### application will prevent or reduce flowering and pithy tissue formation. Biomass Increase ETHREL® 

### used to preventflowering can also result in increased biomass accumulation and recoverable sugar yield. 

# PINEAPPLEAND SUGARCANE

RATE PER SPRAY

ACRE VOLUME 

### APPLICATION TIMING SPECIFIC COMMENTS RESTRICTIONS



### 2 

### -4 quarts 

### tOO to 

### 500 "Bearing age' about 12 Proper rate will vary with Do not graze pineapple

# ~ gallA months after planting. local growing conditions, forage treated 'Nith Generally about 6 months varietfes, plantation ETHREL® Do not harvest 

### priorto desired harvest. management practices pineapples treated with

## ~**~'1'0I' ~**  and time ofyeaL Use the ETHREL@soonerthan2 

### 10

.... 'V' 

### ...J_,

.. -'- **'I** 

### I higher rate where earlier days afterthe last f'"r--O

# V'r I 

# 1.**~'I'** 

# 1. 

# F" t 

## V'v\.S 'harvest is desired. Apply application.

t -4 quarts 100 to 300 Vllhen the first fruit begin \ gallA to change color.

# ,~ b.

# e.J-**-r~** W

## I 

# Y2.. 

# +f.I 

# 2. 

# f> \ 

# f..,ii.s" [**~J** { pmts/ 7gallA Just prior \ minimum initiation.

# ~~eJ -f'l'O"",I..I" 

# Y'l. If, 

# i to flower 'll/hen pineapple foliage is 

### dr< Use a broadcast spray, 

# I thoroughly cover both foliage and fruit. Use the higher rate during periods of cool or cloudy weather when normal ripening has slowed.

# AP~y by fixed wing a:Jaft

# IDo not harvest sugarcane or helicopter using equip- treated with ETHREL® 

### ment designed to give' soonerthan 2 months \ unifOrm coverage. afterthe last application. Actual biomass increase Do not graze sugarcane will be affected by the time forage treatedwith between treatment and ETHREL®. harvest.

I 

### Consider anticipated recoverable sugars as well as biomass to determine optimum harvest date. For Use in Hawaii Only. 

# I I

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE.CURED): A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, uniform "yellowing" ofmature 

### tobacco. ETHREL® reduces curing time, allowing more efficient use of curing barn space, and increased control over harvest schedules. 

### ETHREL® brand Ethephon Plant Regulator increases the capacity of the curing barn by shortening the curing time and allows adjustments in harvest schedules. ETHREL

### ®can be used as a directed spray to the bottom or middle portion ofthe tobacco plant or as an over-the-top spray. ETHREL® is not intended or recommended for use on immature tobacco.

ETHREL® 

### Crop Situation Pints/Acre Specific Directions DIRECTED 

### 4 Use drop nozzles. Choose TG or OC spray tips designed to apply 50

- 60gpa at 35-40 psi and at SPRAY tractor speed of 2-3 mph. Use 2 nozzles per row; one on each side of the row dropped low APPUCATION enough to direct the spray to the leaves to be ripened and harvested. Thorough spray coverage is essential. With a directed spray, be sure to harvest all leaves with 20% or more yelJowin-g. OVER-THE-TOP 

### 4-8 Treat only when leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a tendency to be more rank or when temperatures are lower than normal. Always test spray to**d~ermive** if the tobacco is mature enough to respond to treatmentwith ETHREL®. 

### Us: n ..."

### ~ Apply over-the-top ETHREL® spray as a fine mist using three nozzles (one nozzle

# t~over the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similarto the application pattem ofsystemicsuckercontrol agents. Use a spray pressureof40 to 60 psi.


### USE LIMITATIONS Do not apply ETHREL® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality.
Do not allow the crop to over ripen in the field after using ETHREL® brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do not treat before anticipated major storm which could prevent harvestand result in crop loss. Do notapply ETHREL® brand Ethephon Plant Regulator ifrain is expected within 6 hours.
Do not harvesttobacco treated with ETHREL ® brand Ethephon Plant Regulator soonerthan 2 days afterapplication. Follow use rates listed above for labeled uses. Do notexceed 8 pints ofthis product (2 Ib ethephon) peracre peryear. 

### APPLICATION TIMING Successful results with ETHREL ® brand Ethephon Plant Regulator call for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the proper treatment timing and the number ofleaves per stalk ready for harvest, test spray several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves that fail to yellow in 72 hours are not mature and are not ready for ETHREL®treatment. Wait a few days to permit further natural maturing, then make anothertestspray or"maturity" check. Determine acres to treat by first confirming the numberofleaves per plant thatwill color, then use barn capacity to calCUlate the number ofacres to treat. A test spray can be prepared by mixing 4 teaspoons of ETHREL® brand Ethephon Plant Regulator in 1 quart of water. Apply about 1 ounce to each test plantcoveriQg**al~I~..v~** with a fine mist. ETHREL ®will notcolor immature leaves. To avoid quality loss andfur'

# P~~~;JP, harvest any yellowed leaves prior to application. Use lower rates under most conditions. Limituse of higher rates tocool (below6soF at the time oftreatment) slow ripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREL® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leavej have 

### It reached the desired color intensity. 

### t\ II tof

### ~

# oI~'4~Harvest can commence 48 hours after ETHREL® brand Ethephon Plant Regulator application. To determine harvest timing and avoid quality loss or leafdrop, closely monitortreated crop andweather conditions. 

### CURING ETHREL 

### ® BRAND ETHEPHON PLANT REGULATORTREATEDTOBACCO Curing procedures are as much an art as a science and each cure must be judged on the basis oftobacco condition, interval between treatment and harvest, weather and type ofcuring faCility before prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must be taken to observe and control the curing process closely, especially**du~inq** the late "coloring" and early"drying" stages ofthe leaf. ['

### ~

# eel

# "1**~** Ethephon treated tobacco will have started the coloring process when harvested, reducing the time required in the coloring ph se of curing, Treated tobacco should be dried faster. Iftobacco leaves are green orcontain some green when harvested, it may be nec ssary to colorthem for a few hours. Ifthe leaves are completely yellow, temperature and ventilation must be adjusted in a manneradequate to dry the tobacco as fast as possible without scalding. Once the leaf is dried 

### (3f4 dry), you should follow normal procedures for curing. Since ETHREL ®treated leaves cure faster, treated and untreated leaves should not be cured together in the same barn.


# TOMATOES
TOMATOES (PROCESSED): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates and concentrates tomato ripening increasing recoverable fruit yield from a once-over harvest. Plant Regulator application starts the normal ripening process earlier and increases the rate of ripening of mature green fruit concentrating maturity. Concentrated maturity enables high recoverable yields of ripe tomatoes in once-over harvest. Early concentrated maturity extends the normal harvest season and helps growers schedule harvestand handling more effectively. TOMATOES (FRESH MARKET IN CALIFORNIA): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates tomato ripening increasing the earlyyields ofmarketable ripe fruit.

ETHREL® Crop Situation PintsfAcre Specific Directions Remarks PROCESS 

### 11f4-31f4 Apply 1 

### Y. to 3 

### Y. pints per acre of Apply ETHREL® when desired tonnage of fruit has TOMATOES ETHREL® brand Ethephon Plant reached marketable size 

### aod maturity. Check fields Earlyand Regulator in a minimum of 20 gallons closely for stage and degree of uniform maturity prior to Midseason Crops per acre for ground application and a application. Sample several plants throughout the field to
orWarm minimum of 10 gallons per acre for determine proper spray date. Sort, weigh and calculate Conditions aerial application. Apply when 5% to the percent fruit which is red and pink, including breakers. 15% of the fruit in the field are red Fruit size alone is not an adequate indicator. Observe 

### aod pink (including breakers) 

### aod specific directions to determine treatment stage for your there is sufficient maturegreen fruit to situation. Walk treated fields frequently to evaluate crop produce the desired tonnage. condition. Maintain normal cultural practice between Under high temperatures (above 85 treatment and harvest. Timely harvest is essential for F), rates as low as 1 

### 1f4 pintsfacre maximum return of high quality fruit. Consult processor can be effective. representatives concerning delivery schedules 

### aod Thorough coverage is essential. Foe quotas priorto appl"icaflon ofETHREL®. ground or air application choose Consult your local Bayer CropScience Representative, equipment and spray volumes that Extension Horticultural Specialist or Farm Advisor for will assure uniform spray coverage of suggestions on the proper use of ETHREL® when fields foliage 

### aod fruit. Overdosing from have variable plant vigor due to differences in soil overlapping swaths or spray nozzle conditions or cultural practices and for rates of fruit patterns 

### cao cause severe foliage ripening as affected by temperature, within the rate and injury. If bands are sprayed over the timing limitations shown on the label. row, reduce the amount of ETHREL® used 

# '0 proportion to the area actuallytreated. Observe treated fields closely 

### aod harvestfruit at proper maturity.

# TOMATOES (continued) 

## :tvA

, v 

### ETHREL® Specific Directions 0

## T

# vv\~ Crop Situation P"mts/Acre 

### Remarks 

### PROCESS 3114-61/2 Apply 3 

### Yo to 6 

### Yo pints per acre of ETHREL®

## ~Tp~d )larves! at proper maturity. TOMATOES Ethephon Plant Regulator in a minimum of 20 gallons per 

### ifemperatures 

### above gO°F may Late Season or 

### acre for ground application and a minimum of 10 gallons· cause fruit to ripen sooner whereas Coastal Crops or 

### per acre for aerial application. Apply when 5% to 30% of temperatures below 65" F retard Cool Conditions 

### fruit in the field are red and pink (including breakers) and natural color development and may there is sufficient mature green fruit to produce the desired extend the time between treatment tonnage. Maximum response is achieved when fruit to be and harvest. treated is 5 to 15% pink and red. Use the higher rate of ETHREL ® when nighttime temperatures are cool (below 65°F) or vegetative growth is dense. Thorough coverage is essential. For ground or air application choose equipment and sorav volumes thatwill assure uniform sorav coveraqe FRESH MARKET 11/4-5 Apply ETHREL ®when desired tonnage offruit has reached Check treated fruit frequently and TOMATOES marketable size and maturity. generally 3 to 6 days before harvest at desired maturity. When California desired harvest date. Expect onl¥ne harvest from treated programming harvest. spray a areas. D, 

### W 

# octe./·r different block each day aod Apply 1 

## y,. to 5 pints per acre of ETHREL® b?ara;,thePhon harvest blocks daily in the same Plant Regulator in a minimum 01 40 gallons Iper acre for sequence. ground application and a minimum of 10 gallons per acre for aerial application. Thorough coverage is essential. For ground or air application choose equipment and spray volumesthatwill assure uniform spray coverage Use the higher rate and longer preharvest interval on late season crops, when temperatures are cool (generally below 85°F) and foliage is dense. Under high temperatures, rates as low as 1 1/4 pints per acre have been effective while reducing foliage damage particularly on more sensitive varieties

- see above. 

### Use Limitations Do not apply before there is sufficient mature green fruitto produce the desired tonnage. ETHREL ® brand Ethephon Plant Regulator will not ripen immature green fruit. Some yellowing and general aging offoliage may be observed following treatment. Do not treat plants with poor root systems or growing under stress due to poor soil conditions, drought, d'lsease or insect damage. Treatment ofweak plants will result in rapid loss of foliage cover increasing sunburn and sun scald potential, especially under high temperature conditions. Do nottreatwhen sustained temperatures above 105°F are anticipated. Do not treat sensitive varieties during period when temperatures exceed 1DDoF. Foliar damage is more severe on certain varieties such as VF 10, VF 315, VF 145, 21-4, and 13L. During periods ofhigh tempera1ures use the lower rates on sensitivevarieties. Do nottank mixwith sun protection products, sun protection whiteners, spray adjuvants orother additives. Do notapply ETHREL ® brand Ethephon Plant Regulatorto more acreagethan can be harvested in 2 to 3 days. Do notapply ETHREL® brand Ethephon Plant Regulatorto varieties known to soften rapidly orshatterwhen ripe. Do not use on greenhouse tomatoes. Do not harvesttomatoes treatedwith Ethrel® brand Ethephon Plant Regulatorsoonerthan 3 days after lastapplication. Follow use rates listed above for labeled uses. Do notexceed 6.5 pints ofthis product (1.63 Ib ethephon) peracre peryear.

# WALNUTS
WALNUTS IN CALIFORNIA: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulatorwill loosen walnuts for increased efficiency of mechanical harvest, promoteearlier harvest, improve hull removal, and increase recoverable yields from a once-over harvest.


### Crop 

## ETHREL® Specific Directions Situation 

### Pints/Acre Expect best results with spray concentrations of California 

### 3-5 300 to 

### 900 ppm. 

### Refer to

### ~ preparation chart below. Under ow temperatures 

### and/or low humidity conditions use the higher label rates. Expect less time between application 

# 00' harvest with higher label rates. For best results treatwhen air temperatures are between 60°F 

# 00' 95°F. Expect reduced effectiveness if above 90°F with low humidity due to spray evaporation. Thorough uniform coverage of walnut hulls is essential 

### for maximum hull split and nut loosening response. Choose equipment that provides maximum spray penetration of the entire tree canopy. 

### U,e large air carrier sprayers where tree size jeopardizes coverage. Orvolute sprayer attachments may help.



### USE LIMITATIONS Treatment priorto packing tissue brown (mature) stage may reduce nut quality. Some leafdrop is associated with treatment. 

### Remarks
Walnuts 

### are mature when the 

### packing tissue between kernel 

### halves completes browning. 

### Collect nut samples from throughout the tree canopywhen determining percent nut maturity. Advancing Harvest

- Apply when 95-100% of the nuts have reached maturity. Inspect frequently 

# 00' harvest 

# " soon 

# " adequate hullability occurs generally 10-16 days after treatment depending 00 variety and weather conditions. Plan second shake 10-12days afterfirst shake. Once Over Harvest

- Variety, growing conditions and weather affect maturity and the opportunity for once over harvest. Contact a local fieldman or Farm Advisor to determine if once over harvest can be expected in your situation. Apply to mature walnuts 10days prior to expected harvest date. Expect actual harvest to range from 7-12 days aftertreatment.

Do not treatdiseased, lowvigor ormoisture stressed trees as excessive leafdrop may occur. Assure that dosage rates are measured accurately since rates higher than recommended may result in tree injury (such as excessive defoliation, reduced catkin formation and twig dieback). Do not harvestwalnuts treated with ETHREL ®soonerthan 5 days after last application. Do notexceed 5 pints ofthis product (1.25Ib ethephon) per acre peryear.

ETHREL®SPRAY PREPARATION CHART SgrayVolume (gallons/acre) ETHREL® Rate 

### 100 200 300 400 Pints/A Lbs/A Concentration (gpm) 

### 3 0.75 

### 900 450 300



## - 4 1.00


## --- 600 400 300 5 1.25



## --- 750 500 375 500



## ---

--- 300

# MISTLETOE REMOVAL
DWARF AND LEAFY MISTLETOE REMOVAL: A foliar spray of ETHREL® brand Ethephon Plant Regulator will 

### remove dwarf mistletoe shoots in ornamental conifers and leafy mistletoe from ornamental deciduous trees.


## ETHREL® Crop Situation Amount DWARF 

### 2 pints MISTLETOE ON 

### pee ORNAMENTAL 20 gallons CONIFERS DOUGLAS FIR 

### 1

### pint ORNAMENTALS 

### pe, 20 gallons

LEAFY 2 quarts MISTLETOE 

### pe, 

## ON 20 gallons ORNAMENTAL DECIDUOUS TREES 

### Specific Directions Remarks 

### Apply as a foliar spray to dwarf Applications made in conjunction with sylvicultural 

### mistletoe 

### shoots before mistletoe mistletoe management will prevent spread of the seed 

### dispersal. 

## Fo' effective mistletoe parasite to other parts of the tree and removal, all mistletoe shoots must 

### othertrees. be sprayed to wet. Use of a non- Mature needle drop, that normally occurs in the ionic 

### surfactant 

### at recommended fall, may be hastened by the use ofETHREL®. rates may increase effectiveness. Treat any mistletoe regrowth before Applications of higher rates on Douglas fir may seed dispersal. result in excessive needledrop. Make applications afterfall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. 

## Foe effective mesquite may be difficult to control with a single removal, all mistletoe shoots must application and retreatment may be necessary. be sprayed to wet Use of a nonionic surfactant 

### at recommended rates may increase effectiveness. Any mistletoe regrowth should 

### be treated during 

### the labeled application window.


# FRUIT ELIMINATION (Ornamental Use Only)
UNDESIRABLE FRUIT ELIMINATION: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator will reduce or eliminate undesirable fruit developmenton apple, crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8 to 12 ounces Apply as a fonar spray at the flower Application must be made before fruit set for best CRABAPPLES 

### pe, bud to full bloom stage, prior to fruit results. set Wet foliage thoroughly. Over Do not treat weak trees or trees under stress 20 gallons application of 

### ETHREL® Plant (drought, insect or disease damaged trees) as Do not exceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result ounces (0.15 oz. leaf drop and/or tree defoliation.

ai/gallon) per 

### U,e higher rates when Some leaf drop or temporary leaf yellowing may application. temperatures are cool. occuraftertreatment CAROB 6 ounces Apply 

### a, a foliar spray. Wet all Do 

### not use 00 

### small red fruited varieties of (Ceratonia sifiqua) 

### pe' foliage thoroughly. Amount of spray crabapple 

### a, fruit elimination will 

### oot be 20 gallons will depend on tree size. satisfactory.
OLlVE* 12 ounces (Olea europaea) 

### pe' 20 gallons *This recommendation is notintended to be used on commercial fruit production as a thinning agent 

# "of 20 I

# oleJ.~ 18 

## 'E- 

# J

# TURF

An application ofEthrel slows the growth ofturfgrass8sthus reducing the required frequency ofmowing and the volume ofclippings collected.

SITES 

## RATE APPLICATION SPRAYVOLUME Fairways, Roughs & Commercial 6f1ozl1,OOOsqft Apply

### to actively growingturf. Itwill 0.5-4.0 9als/1,000 sq 

### ft Turfgrasses, including BentgraS$ require 

### 7-10 days for ETHREL®to (Fairwaycut), Kentucky 

## act Reapplication intervals: Bluegrass, Perennial Ryegrass, Kentucky Bluegrass-7 wks. 

### Tall & 

### Fine Fescue Perennial Ryegrass-7 wks. Tall/Fine Fescue-4 wks. Bentgrass-4wks. 

### Use Limitations:

Do notallow entrytotreated areas until sprays have dried. For best results, applywith sprayer in sufficient volume ofwaterto provide uniform coverage. ETHREL® is foliarly absorbed. Apply onlyto activelygrowing turf, underfavorable growing conditions, that is not going into a dormancy period. Do nottreatturfgrass with poor root systems orgrowing understress dueto poorsoil conditions, drought, disease or insectdamage. Do not applyto golfcourse greens. Use ofspreaders/stickers with ETHREL® is not necessary. ETHREl® is an acidic product and prolonged exposure to spraydeposits will damage acrylic plastics, certain paints and metals. Rinse thoroughly all exposed acrylic plastic materials and painted surfaceswith a detergent and waterwithin one hourafterexposure to spraydeposits.
Testtankmixes with otherproducts on a small area before using widely.

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. Ifterms are not acceptable, return the unopened product container at once. By using this product, user or buyeraccepts the following Conditions, Disclaimer ofWarranties and Limitations ofLiability. 

### CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it 

### is impossible to eliminate all risks associated with the use ofthis product. Crop injury, ineffectiveness or other unintended consequences may result because ofsuch factors as weather conditions, presence of other materials, orthe manner of use or application, all ofwhich are beyond the control of Bayer CropScience Lp. All such risks shall be assumed bythe userorbuyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABiliTY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE LP'S ELECTION, THE REPLACEMENT OF PRODUCT.



# NET CONTENTS:

ETHREL is a registered trademark ofBayer.

Produced for

BayerCropScience P.O. Box t20t4, 2 T.w. Alexander Drive Research Triangle Park, North Carolina 27709

# (r~eel]

ETHREL® brand Ethephon Plant Regulator (Pending) 01f20ftO, Resubmitted 06f02f10

# ® 

# ETHREL brand 

# Ethephon Plant Regulator ForCommercial OrAgricultural Use Only. Not For Residential Use. For use on Apples, Blackberries, Blueberries, Cantaloupes, Cherries, Grapes, Peppers, Pineapple, Sugarcane, Tobacco, Tomatoes, Walnuts, and forthe removal ofDwaliMistletoe in Ornamental Conifers and Leafy Mistletoe in Ornamental Deciduous Trees and forthe elimination ofundesirable fruit on Apple, Crabapple, Carob, and Olivetrees. ACTIVE INGREDIENT: Ethephon [(2-chloroethyl)phosphonic acidJ*

............. . INERT INGREDIENTS:

................................... 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entiende la etiqueta, busque a alguien para que S8 

### la explique a usted en detalie. (Ifyou do notunderstand the label, find someone to explain itto you in detail.) 

### ..........21.7%



### ........78.3%

For MEDICALAnd TRANSPORTATION Emergencies ONLY Call 24 HoursA Day 1 M

### 800 M

### 334-7577 For PRODUCT USE Information Call1-888M 

### AVENTIS (1 M 

### 888M 

### 283.6847) 

# FIRSTAID
IF IN EYES: 

# • Hold eye open and rinse slowly and gentlywith waterfor 15M20 

### minutes.


## • Remove contact lenses, ifpresent, afterthe first 5 minutes, then continue rinsing.


## • Call a poison control center or doctorfor treatment advice. IF SWALLOWED: 

# • Immediately call a poison control centerordoctorfortreatment advice. 

# • Do not induce vomiting unless told to do so by a poison control centerordoctor. 

# • Have person sip a glass ofwater ifable to swallow. 

# • Do notgive anything by mouth to an unconscious person. IF ON SKIN OR 

# • Take offcontaminated clothing. CLOTHING: Rinse skin immediatelywith plenty ofwater for 15M 

### 20 minutes. 

# • • Call a ooison control center or doctorfortreatment advice. IF INHALED: 

## • Move person to fresh air.


## • If person is not breathing, call 911 

### or an ambulance, then give artificial respiration, preferably mouth·to· moulh ifpossible.


## • Call a poison control center ordoctor for furthertreatment advice. For MEDICAL Emergencies Call 24 HoursA Day 1-800..334-7577. Have the product containeror label with you when callinr:J a poison control center ordoctor orQoinr:J fortreatment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use ofgastric lavage. No specific antidote is available. All treatments should be based on observed signs and symptoms of distress in the patient. Overexposure to materials other than this product may have occurred. Victims of severe overexposure by inhalation should be kept under medical observation for up to 72 hours for delayed onset of pulmonary edema. In a victim of overexposure by ingestion, careful gastric lavage is required due to the possibility of stomach or esophageal perforation. This material is an acid, but the use of alkaline stbstances 

### 10 neutralize itisconlraindicated.

# PRECAUTIONARY STATEMENTS HAZARDS TO HUMANS AND DOMESTIC ANIMALS DANGER Corrosive. Causes irreversible eye damage. Wearsafety goggles when handling. Harmful 

### ifswallowed or absorbed through skin. Do not getin eyes oron clothing. Avoid contactwith skin. Do notinhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials thatare chemical-resistant to this product are listed below. Ifyou want more options, follow the instructions for Category A on an EPA chemical-resistance selection chart. 

### Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, shoes plus socks and protective eyewear. 

### When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard for agricultural pesticides (WPS) 

### [40 CFR 

### 170.240 (d) {4-6)J, the handler PPE requirements may be reduced or modified as specified in the WPS. Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hotwater. Keep and wash PPE separately from otherlaundry. 

## UserSafety Recommendations Users should wash hands before eating, drinking, chewing gum, usingtobacco or usingthetoilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into clean clothing. The contaminated clothing should bewashed before reuse. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofgloves before removing. 

## ENVIRONMENTAL HAZARDS Do not apply directly to water, or to areas where surface water is present orto intertidal areas belowthe mean high water mark. Do not contaminate waterwhen disposing ofequipmentwashwaters. 

# DIRECTIONS FOR USE It is a violation of Federal Lawto use this product in a manner inconsistentwith its labeling. Do notapply this product in away thatwill contactworkers or other persons, eitherdirectlyorthrough drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulations. Read entire label before using this product. 

# AGRICULTURAL USE REQUIREMENTS Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. 

### It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers, and restricted-entry intervals. The requirements in this box only apply to uses ofthis product that are covered by the Worker Protection Standard_ Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical-resistant gloves made ofany waterproofmaterial such as polyethylene or polyvinyl chloride, chemical resistant footwear plus socks, and goggles orface shield. Foroverhead exposure, chemical-resistant headgear is also required. Notifyworkers ofthe application by warning them orallyand by posting warning signs atentrance to treated areas.

2

# STORAGE AND DISPOSAL
PESTICIDE STORAGE Do not contaminatewater, food. or feed by storage and disposal. PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal Law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe Hazardous Waste representative at the nearest EPA Regional Office for guidance. Wastes resulting from the use ofthis product may be disposed ofon site orat an approved waste disposal facility. CONTAINER DISPOSAL 

### Rigid, Non-refillable containers small enoughto shake (i.e., wilh capacities equal to or less than 5 gallons) Non-refillable container. Do not reuse or refill this container. Offer for recycling, ifavailable. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment ora mix tank and drain for 10 seconds afterthe flow begins to drip. Fill the container 114 full with waterand recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this proceduretwo more times. Then offerfor recycling orreconditioning orpuncture and dispose ofin a sanitary landfill.
ETHREL 

### ® BRAND ETHEPHON PLANT REGULATOR Promotes earlier, uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increasesdormant fruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower induction, pineapple maturity concentration, sugarcane flower prevention and biomass increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe from ORNAMENTAL DECIDUOUS TREES. Eliminates undesirablefru·rt onAPPLE. CRABAPPLE, CAROB, and OLIVE trees. 

### GENERAL INFORMATION For local recommendations on rates, spray volumes (gallons ofwater per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, Horticultural SpeCialist, Bayer CropScience Representative or Farm Advisor for his experience with this product in your area. 

### APPLICATION VOLUMESAND SPRAY COVERAGE Thorough spray coverage 'IS essential to achieve max'lmum product effectiveness. Spray coverage is affected by choice of equipment. nozzle selection and spray boom setup as well as spray pressure, plant size and canopy density. For both air and ground applications, it is important to choose an equipment setup that will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will varywith the size and density ofthe plant canopy and the equipment used. In California and Arizona use a volume of no less than 5 gallons peracre foraerial applications. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do not contaminate water used for irrigation ordomestic purposes. Avoid spray driftto nearby crops as th'ls product will cause modifications in plant growth. Plant injury or reduced yields will result. Do not plant anothercrop within 30 days after treatment. DO NOT MIX ETHREL® WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. Add 

### y,; to 

### o/.i of the required amount ofwater to the spray tank. Start agitation. Add the required amount of ETHREL ® brand Ethephon Plant Regulator. Mix onlythe amount ofspray you expect to use each day. Do not allow mixed solution to stand overnight. Do not use ETHREL® brand Ethephon Plant Regulatorwith additives otherthan recommended on this label. Avoid spills ofconcentrated product on spray equipment or airplane parts. IMMEDIATELY RINSE ANY SPILLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. IMPORTANT: Do not apply ETHREL ® brand Ethephon Plant Regulatorthrough any type ofirrigation system. Do not use this product for purposes otherthan those listed on the label. Do not exceed the rate of ETHREL® brand Ethephon Plant Regulator peracre peryear recommended on this label.

3

### SPRAY DRIFT Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift may result in illegal residues or injury to adjacent crops and vegetation. in the form ofleafyellowing and defoliation. To avoid spraydrift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods oftemperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFTAT THEAPPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field crops. These requirements do not applyto forestry applications, public health uses orto applications using dry formulations. 1. The distance ofthe outer most nozzles on the boom must not exceed 3/4 

### the length ofthewingspan or rotor. 2. Nozzles mustalways point backward parallel with the air stream and never be pointed downwards more than 45 degrees. Wherestates have more stringent regulations, they should be observed. The applicatorshould be familiarwith and take into account the information covered in the Aerial Drift ReductionAdvisory below: 

### AERIAL DRIFT REDUCTIONADVISORY INFORMATION ON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and Temperature Inversions). CONTROLLING DROPLET SIZE Volume

- Use high fiow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higher flow rate nozzles instead ofincreasing pressure. Number ofnozzles

- Use the minimum numberofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. Significant deflection from horizontal will reduce dropletsize and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 3/4 

### ofthe wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEIGHT Applications should not be made at a height greater than 10 feet above the top ofthe target plants unless a greater height is required for aircraft safety. Making applications atthe lowest heightthat is safe reduces exposure ofdroplets to evaporation and wind. SWATH ADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance should increase, with increasingdrift potential {higherwind, smaller drops, etc.}. WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and howthey affectspraydrift. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet evaporation is mostsevere when conditions are both hot and dry.

4TEMPERATURE INVERSIONS 

### Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air 

### mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

### to the lightvariable winds common during inversions. Temperature inversions are characterized by increasing temperatures with altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, 

### if fog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. SENSITIVE AREAS 

### The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray depOSits will damage acrylic plastics, certain paints, and metals. Rinse thoroughly all exposed acrylic-plastic materials and painted surfaces with a detergent and waterwithin one hour after exposure to spraydeposits.

5

# APPLES
APPLES: A foliar spray of ETHREl® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples, making harvest by 

### hand or machine easier and more efficient. ETHREL

### ® applied in combination with FRUITONE@ N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruit. Applied to young trees, ETHREL® 

### will suppress vegetative growth and promote flower bud formation.



### Crop Situation FRUIT LOOSENING
1. EARLYAND MIDSEASON MATURING VARIETIES (varieties maturing with Mcintosh or earlier) ETHREL® PintslAcre

2 112 Specific Directions Apply a foliar spray to apple trees 7 to 14 days priorto normal antiCipated harvest. Use sufficient water for thorough uniform spray coverage. The type ofsprayer used and size of trees will affect volume required. Observe fruit daily as the proper picking period is shorter with ETHREL® treated fruit than untreated fruit. Do not exceed 1.25 pounds 

### ailA per season. Remarks
ETHREL® provides several beneficial responses 

### on apples. Depenolng 

### on rate and time of application ETHREL ®will: promote fruit loosening, 

### promote uniform ripening and coloring without loosening, promote thinning and return bloom, and 

### increase flower bud development in young trees. Fordesired response, follow specific directions. Treat when air temperatures are between 60° F and 90° F. However, application may be made at 50° F under rising temperature conditions. If daytime temperatures are warm, color response from ETHREL® 

### treatment will be reduced, but ripening and loosening effects will be accelerated. Cool weather may extend the interval between treatment and harvest. 2. LATE Do not allow fruit to become overripe on trees. MATURING Fruit intended for fresh market must be checked VARIETIES IN for quality and maturity. Color alone is not an THE EASTERN adequate guide for fruit maturity. Use a pressure UNITED STATES gauge or other suitable methods for determining (varieties internal maturity. Fruit over-matured when maturing**late~,** 

### harvested and stored may soften sooner than than Mcintosh) untreated fruit.

## ~~~~-----+------------~ PROMOTION OF Apply foliar spray of ETHREL® and a UNIFORM preharvest drop control chemical RIPENING AND registered for use on apples such as the COLORING OF RED product FRUITONE® N. Use the VARIETIES preharvest drop control product according WITHOUT to label directions. Begin spraying 2 to 3 LOOSENING weeks before normal harvest period and about 1 to 2 weeks before desired 1 EARLY OR MIDSEASON MATURING VARIETIES (varieties maturing with 

### 1 ·4 harvest date. Apply as a normal dilute spray using sufficient water for thorough uniform coverage. Actual volume will depend on the type of delivery of sprayer used and size oftrees. Use the lower rate for apples intended for 

# f--===-'------+------I storage. 2

-4 Do not exceed 1.25 pounds ai/A per Mcintosh or earlier) 

### 2. LATE 

### MATURING season. VARIETIES (variej"les maturing later than Mcintosh) Do not apply ETHREL® 

### to more acreage than can be harvested in 1to 2 days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of preharvest drop vary according to location and variety, follow directions on the**FRUITON~** 

### N label. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

6ETHREL® 

### Crop Situation Pints/Acre THINNING AND RETURN BLOOM



### 1. Most Varieties 

### 1.5

- 4



### 2. Difficultto Thin 

### 3-6 Varieties Such as Golden Delicious

INCREASED FLOWER BUD DEVELOPMENT 

### 1. NON-BEARING 

### 2-8 TREES



### 2. BEARING 1/2 - 3 TREES


### Use Limitations 

# APPLES 

# (continued)

Specific Directions Treat 10 to20 days afterfull bloom. Forgreaterthinning, this productcan be mixed with AMID-THIN®W, SEVIN'"brand4F Carbaryl Insecticide, SEVIN® brand 80 WSP Carbary) Insecticide, SEVIN® brand 80 S Carbaryl Insecticide or SEVIN® brandXLR Plus Carbaryl Insecticide for use on apples in accordancewith the most restrictive ofthe AMIDTHIN®W, SEVIN® and ETHREL® label limitations and precautions. No label dosage rates should be exceeded. ETHREL ®cannot be mixed with any product containing a label prohibition againstsuch mixing. Consult local extension recommendations. Addition ofa non-ionic surfactantcan enhance treatment effectiveness. Buffering spray solution to a pH of3 to 5 can improve performance where water is alkaline. Use a sprayvolume sufficientto covertrees thorouQhlv and uniformlv. Spray trees thoroughly and uniformly to the point of runoff. Use the higher rate on more vigorous trees.
Treat 2 to 4weeks afterfull bloom.

To help minimize fruit thinning, delay application until 6 weeks after full bloom and after June droo. 

### Remarks Regulating cropping from one season to another is 

### a problem. Whenever a high percent of the spurs and lateral buds bloom in a single season severe alternate bearing can develop the fOllowing year. 

### To overcome this problem 05e ETHREL® 

### or a combination of ETHREL® plus AMID-THIN® W or ETHREL® plus one of the SEVIN® products listed under Specific Directions applied 7 to 21 days after full bloom. The program to use will depend on the amount ofthinning required and the biennial bearing history ofyour orchard. Expect Red Del"icious to show a reduction of"type" and fruit size particularly on trees understress. Use ofhigher label rates may reduce fruit size.

To increase flower bud developmenton non-bearing trees apply a foliar spray of ETHREL® 2 to 4 weeks after bloom. Treatment can result in excessive fruit thinning and reduced fruit size and yield reduction the year of usage. ETHREL® should reduce vegetative growth and increase flowering the following spring. Trees should be large enough to support a crop of apples beforetreatmentto initiate flower buds.

The use of ETHREL ®brand Ethephon Plant Regulatorcan result in overthinning and reduced fruit size. Avoid double coverage and use on low vigortrees. Environmental factors can affect thinning ard return bloom, 

### it is advisable to obta·ln experience under your conditions by initially testing only a small percent ofyourtrees each yearwith anyone program. User must consider risk ofexcessive fruit thinning and fruit size reduction when using ETHREL® brand Ethephon Plant Regulatoron young treesjuststarting to bear. Treatonly vigorous trees since excessive growth reduction will result in weak trees. For best results a thorough uniform spray is needed. A wetting agent may improve spray coverage. Do notgraze or feed cover crops grown in treated apple orchards. Do not harvest apples treated with ETHREL ®brand Ethephon Plant Regulator soonerthan 7 days after last application. Fruit size reduction mayoccurwhen used to obtain early maturity, especially iffruit is small atrime oftreatmen!. ETHREL® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruit quality and size. Follow use rates listed above for labeled uses. Do not exceed 8.0 pints ofthis product (2.0 Ib ethephon) peracre peryear.

7

# BLACKBERRIES
BLACKBERRIES IN OREGON AND WASHINGTON: A foliar spray of ETHREL® brand Ethephon Plant Regulator will concentrate maturity and loosen fruit, improving harvesting efficiencywhile reducing cane injuryfrom mechanical harvest

ETHREL® 

### Crop Situation Pints/Acre Specific OirecUons Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity, Use ETHREL®· 1) early in the harvest season to 

## AND apply a foliar spray of ETHREL® at least 3 reduce the number of pickings or 2) treat later in WASHINGTON 

### days prior to expected harvest when air the harvestseason for a once-overfinal picking. (Cultivars temperatures are between 60°F and gO°F Chehalem and rain is not predicted within 24 hours. Thornless and Use sufficient volume to insure thorough Evergreen) and uniform wetting offoli§ge and fruit. 

### Use Limitations

Do notspray more than can be harvested on the third day following treatment as considerable fruit may drop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants, Do not harvestblackberriestreated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 3 days after lastapplication. Do notexceed 8 pints ofthis product (2 Ib ai ethephon) per acre peryear,


# BLUEBERRIES BLUEBERRIES: A foliar spray of ETHREL® brand Ethephon Plant Regulator concentrates maturity of blueberries for easier and more efficient harvest. A foliar spray of ETHREL ® brand Ethephon Plant Regulatorwill abort black barrenbeny (Aronia melanocarpa) flowers and/orfruit growing in Maine lowbush bluebeny fields reducing the numberof undesirable barrenberry fruit harvested with blueberries,

ETHREL® Crop Situation Pints/Acre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foliar spray of ETHREL® brand To concentrate first harvest, apply ETHREL® OF MATURITY Ethephon Plant Regulator at a rate of 4 to brand Ethephon Plant Regulator 'NIlen 15 to 20% AND EARLIER 8 pints in 150 to 200 gallons ofwater per of the berries are blue, To concentrate final FRUIT COLORING acre. Use the higher spray volume and harvest, treat after the first or second picking. (Cultivars Bluecrop, rate on large dense foliage bushes or Harvest blueberries at proper maturity when Weymouth, Jersey, when temperatures are cool. Treat when colored, generally ooe to two weeks after Rancocas, Rubel, airtemperatures are 60 to 90° F. treatment. Observe fruit daily as the proper Bluetta, Erliblue, Thorough uniform spray coverage of picking period for optimum internal and external Wolcott, Croatan, foliage and fruit is essential for maximum quality is shorter with ETHREL® brand Ethephon Murphy, Angola, fruit maturation aod coloration. To aid Plant Regulator treated fruit than with untreated Morrow, Garden uniform wetting of plants, use a wetting fruit. High temperatures (90 0 F) accelerate fruit Blue, Trifblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 100 gallons or X-77 at 2.0 pints per ETHREL® treatments may increase fruit with 100 gallons. stems, slightly decrease fruit size, soluble solids and acidity. ETHREL® may not induce internal ripeninq as rapidly as fruit color. BLACK 

### 4-8 Apply 4 10 8 pints per acre of ETHREL ® Use the lower rates ofETHREL ® brand Ethephon BARRENBERRY brand Ethephon Plant Regulator in 100 to Plant Regulator when black barrenberries are CONTROL IN LOW 200 gallons of water per acre for ground between 90 to 100% petal fall and use the higher BUSH sprayers and 10 gallons ofwater per acre rates of ETHREL® when black barrenberry fruit is BLUEBERRIES IN for aerial application. 1/8 to 3/16 inch in diameter. This is generally 7 to MAINE Thorough uniform spray coverage 

### i, 10 days after blueberries are in the same stages essential. To aid in uniform wetting of of development. Harvest blueberry fruit when plants, use a wetting agent such as X-77 ripe, generally6to 8weeks after application, atO. 1 % ofthe spray volume. 

### Use Limitations

Applicationsto cultivars otherthan those l'isted above may cause excess'lve stem'lness and/or premature crops. Make no more than one application perseason. Ifused for barrenberrycontrol in Maine, do not make a second application for blueberry concentration ofmaturity or coloring. Do nottreat blueberry plants underdrought stress orexcessively high temperatures as defoliation and reduced yield may reault.

# CANTALOUPES
CANTALOUPES IN CALIFORNIA, ARIZONA, AND TEXAS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes abscission (slipping) offruit allowing more efficientand economical harvesting.



### ETHREL® Crop Situation Pints/Acre Specific Directions Remarks CALIFORNIA, 

### 3 Good spray coverage 

# • The effect will be faster at higher temperatures_ Proper timing of ARIZONA, important 

### roc producing ETHREL® 

### treatment is critical, 

### but may vary from season to TEXAS uniform abscission. Use 40 

### season. Fruit quality, in terms of soluble solids and flesh color, DC more gallons/acre 

### foc does not"Improve following treatment. Therefore, ETHREL®should ground aod 

### 10 DC more 

### not be used until after fruit has developed marketable levels of gallons/acre 

### foe aerial soluble solids and flesh color. ETHREL® promotes abscission of application. (Aerial immature fruit as well as marketable fruU. Thus, using ETHREl ® applications 

### ace only too soon will result in poorly colored fruit with substandard soluble permitted in Texas.) solids. 

### Be prepared 

### to harvest Observe treated fields frequently and pick fruit when marketquality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long will lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary following treatment. Plants with low vigor will not respond properly, with temperature. Be sure Do not plant anothercrop within 30days aftertreatment. 

### to coordinate your harvesting schedule with :vour packer/shipper. 

### Use Limitations

ETHREL® brand Ethephon Plant Regulatorshould not be applied when nighttemperatures are below**60~F.** Treat only those fruit that have a fairly uniform fruit set, have vines in good condition, and have fruit with marketable soluble solids and internal flesh color. Do not treat fields where soluble solids are running less than 10%. Do not harvest cantaloupes treated with ETHREl ® brand Ethephon Plant Regulatorsoonerthan 2 days after last application. Do notexceed 3 pints ofthis product (0.75 Ib ethephon) per acre peryear.

9

# CHERRIES Except California CHERRIES: A foliar spray of ETHREL® brand Ethephon Plant Regulator loosens fruit and promotes early uniform ripening, and reduces the shakerforce neededto mechanically harvest fruit. These effects are important for increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree injury. DO NOT USE ON CHERRIES IN CALIFORNIA A fall application of ETHREL® to S\Neet cherries in the Pacific Northwest area increases dormant bud hardiness and delays bloom the following spring. 

## ETHREL® Crop Situation Pints/Acre Specific Directions Remarks TART Dilute Spray Apply 

### a, a dilute spray with sufficient water 

### foe CHERRIES 1 thorough, uniform coverage. 

### The optimum spray volume will depend on tree size, planting density and €!quipment used. Concen- Concentrate sprays, generally less than 100gallons per trate Spray acre, require uniform coverage for optimum response.



### 2/3 to 1

SWEET Dilute Spray Apply 

### a, a dilute spray with sufficient water for Expect 

### a longer treatment to CHERRIES 3 t04 thorough uniform coverage. Actual volume will depend harvest interval with lower rates. (varieties such as on the type of delivery, sprayer used and size oftrees. Windsor, Use low rates on the light or yellow-colored varieties. Napoleon-Royal Anne, Emperor Francis) Concen- Concentrate sprays, generally less than 100gallons per trate Spray acre, require unifol1T1 coverage fOr optimum fesponse. 

### 2-3

INCREASED 

### 3 Treat in first two weeks ofSeptember. A fall application of ETHREL® will DORMANT increase fruit bod hardiness by FRUIT BUD decreasing the chance for winter HARDINESS iniury and delaying bloom by 3 to 5 AND DELAYED days which may help avoid frost SPRING BLOOM injury. Treatment of early flowering (Sweet Cherries varieties may delay bloom to better in the Pacific coincide with pollination from other Northwest) varieties. 

### Use 

### Limitations Not for use on cherries in California. Apply ETHREL® brand Ethephon Plant Regulator in a minimum sprayvolume of50gallons per acre. Do not treat too early as this can cause earlyfruit drop with stems attached. Some gummosis ofcherry tfees is associated with treatment. Hightemperatures during and afterapplication may cause severe gummosis. Do nottreattreeS that had severe gummosis the previous year as tree damagewill result Do not apply to trees that are of low vigor or have experienced severe stress (such as winter iniury, drought, or disease), since gummosis will be excessive, particularly when high temperatures and/or drought followtreatment. Ifpossible, irrigate orchardsto prevent drought stress resulting in gummosis. Do not harvest cherries treated with ETHREL® soonerthan 7 days after last application. Atthe time ofapplication, all fruit including those inside thetree canopy, should be in stage 3 as indicated by rapid size increase and the presence of ground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and as"F. Do not treat when air temperatures exceed a5"F. Uniform coverage is important, concentrated sprays associated with erratic application can result in gummosis andtip dieback. Some early leafyellowing and drop may be noted following application. Slight gummosis and individual fruit size reduction may result with fall application bud hardinesstreatment. Follow'use rates listed above for labeled uses. Do not exceed4.0 pints ofthis product (1.0 Ib ethephon) per acre peryear.


### to

# GRAPES (Only in California andArizona)
GRAPES (TABLE GRAPES IN CALIFORNIAAND ARIZONA): An application of ETHREL

### ® brand Ethephon Plant Regulator promotes early uniform color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga, Queen and Tokay allowing more efficient harvests ofqualityfruit. GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL® brand Ethephon Plant Regulator will hasten maturity of Thompson seedless grapes resulting in reduced acids, increased sugars and increased raisin quality.



### Crop Situation TABLE GRAPES (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)


### Use Limitations Table Grapes 

### ETHREL® Pints/Acre



### 112 - 2



### 1-2

1-2 Specific Directions For high temperature conditions (above 85QF) use lower rates of 1/2 to 1 pintper acre. For low temperature conditions (but above 65°F) use higherrates. Apply in sufficientwater to wetvines and fruit clusters uniformly, using conventional ground sprayers. Treatwhen 5

- 30% ofberries showcolor. Treat Tokays when 5

- 15% of berries showcolor. APply as a foliar spray at 5% berry softening. Treat when 5

- 30% of berries showcolor. 

### Remarks HalVest fruit at desired maturity and quality as indicated by sugar content, acidity and color. This is generally two weeks or more aftertreatment. Watch treated areas closely and harvest before berries become too dark. For more information regarding local experienceswith this producton grapes, consult your Farm Advisor oc Extension Viticulturist.



### A foliar spray of ETHREL® will hasten maturity of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more infonnation regarding local experience with this product on 

## Inraoes consult"vour Farm Advisoror Extension Viticulturist.

Rates higherthan t pinUA may increase the incidence ofcracked fruit and should be used only in areas or during weather conditions where grapes have been especially hard-to-color in pastseasons. Some berry softening is associated with ETHREL ® brand Ethephon Plant Regulator treatment ofsome varieties Vllhich may limit or influence storage considerations. Do notstore Tokays. Do not harvestgrapes treated with ETHREL@brand Ethephon Plant Regulator sooner than 14 days afterlast application. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) peracre per year. Raisin Production (Thompson Seedless) Do not applyto grapes understress from insectdamage or moisture stress. Observe treated vineyards closely and harvest at proper maturity as determined by sugaracid levels. Do notexceed2 pints ofthis product (0.5 Ib ethephon) per acre peryear.

11

# PEPPERS
PEPPERS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, unifonn ripening and coloring for more efficient packing and handling offruit



### Crop Situation 

## PEPPERS

Use Limitations 

## ETHREL® Pints/Acre Specific Directions 

### Thorough coverage is essential. For ground or air application choose equipment and spray volumes that will insure uniform coverage offoliage and fruit. 

### Use the higher rate when cool temperatures are 

### anticipated (less than 65"F), when plants are growing vigorously or when foliage is dense to assure thorough wetting ofall leaves and fruit. Use the lower rates with lower spray volumes (1 1/4 

### to 

### 2 pint rate in 

### 20 gallA) and higher rates with higher volumes (3-4 pintsl40 gallA). The 3-4 pint 

### rate in less than 40 gpa may cause foliage burn underhotdl)! conditions. Apply ETHREL® 

### to bell peppers when 10% 

### of fruit are red and chocolate and to chili and pimento pepper varieties when 10 to 30% 

### of fruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL ® will not ripen immature, qreen fruit. Remarks 

### Check several field locations to detennine crop stage and degree of maturity. ETHREL® 

### treatments may reduce total yields 

### 'If applied too early or there is a lack of uniform, mature, green fruit resulting from split fruit set or variable soil cultural practices. Harvest fruit after desired color and maturity are attained, generally 14 or moredays aftertreatment.

Do not apply when prolonged average high temperatures of 95°F aftertreatment are expected. Do not treat when temperatures exceed 100°F. Applications made under high temperatures will accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60°F. Low temperatures after treatment may reduce or negate the effects of ETHREL®brand Ethephon Plant Regulator. Some yellowing and general aging ofleaves will be noted aftertreatment. Do not harvest peppers treated with ETHREL® 

### brand Ethephon Plant Regulator soonerthan 5 days after last application. Do not exceed 4 pints ofthis product (1.0 Ib ai ethephon) per acre peryear. NOTE: Under certain conditions tank mixtures of ETHREL® brand Ethephon Plant Regulator with desiccants containing sodium chlorate could result in the formation ofhypochlorous acidswhich on heating will emit toxic chloride fumes.

12

# PINEAPPLEAND SUGARCANE

CROPANe RATE PER 

## SPRAY USE 

## ACRE VOLUME APPLICATION TIMING SPECIFIC COMMENTS RESTRICTIONS PINEAPPLE 

# , ,
, , FlowerInduction 

### 2 -4 quarts f 

### 100

### to 500 'Bearing age' about 

### 12 Proper rate will vary wilh Do notgraze pineapple 

### ETHREL® applied to gallA months after planting. 

### local growing conditions, forage treated with pineapple plants will 

# [ f Generally about 6 months 

### varieties, plantation ETHREL ® Do no! harvest stimulate uniform priorto desired harvest management practices pineapples treated with initiation offlowering. and time of year. Use the 

### ETHREL® soonerthan

### 2 higher rate where earlier 

### days afterthe last harvest is desired. 

### Apply application. when pineapple foliage is 

### dey, Maturity 1

### -4 quarts 

### 100

### to 300 When the first fruit begin 

### U,e 

## a broadcast spray, Concentration gallA to change color. thoroughly cover both ETHREL ® application foliage and fruit. Use the will stimulale uniform 

# I highe, "te doriog pe'iod, , shell color of cool or cloudy weather development when normal ripening has

, slowed. SUGARCANE 

## i Flower Prevention 2 pints 7 gallA ' Just prior 

### to flower Apply by fixed wing aircraft Do not harvestsugarcane ETHREL ® application minimum initiation. or helicopter using equip- treated with ETHREL®
! will prevent or reduce ment designed 

### to give soonerthan 2 months

flowering and pithy



# I uniform coverage, afterthe lastapplication. tissue formation. i Actual biomass increase Do notgraze sugarcane Biomass Increase will be affected by the time forage treatedwith between treatment 

### aod ETHREL®. ETHREL ® usedto harvest prevent flowering can Consider anticipated also result in <0. f increased biomass 

# , , coverable sugars as well

accumulation and 

# I f as biomass to determine recoverable sugar optimum harvest date. For Use in Hawaii Only. 

# I yield. 

## , 

# i

. ,

13

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE.CURED):A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, unifonn "yellowing" ofmature 

### tobacco. ETHREL

### ® reduces curing time, allowing more efficient use of curing bam space, and increased control over harvest schedules. 

### ETHREL

### ® brand Ethephon Plant Regulator increases the capacity of the curing barn by shortening the curing time and allows adjustments in harvest schedules. ETHREL® can be used as adirected spray to the bottom or middJe portion ofthe tobacco plant or as an over-the-top spray. ETHREL® is notintended or recommended for use on immature tobacco.


## ETHREL® Crop Situation Pints/Acre 

### Specific Directions DIRECTED 4 Use drop nozzles. Choose TG or

### DC spray tipS designed to apply 50

- 60 gpa at 35-40 psi and at SPRAY tractor speed of 2-3 mph. Use 2 nozzles per row; one on each side of the row dropped low APPLICATION enough to direct the spray to the leaves to be ripened and harvested. Thorough spray coverage is essential. With a directed spray, be sure to harvest all leaves with 20% or more 

# Iyellowin-g. OVER-THE-TOP 

### 4-8 Treat only when leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a tendency to be more rank or when temperatures are lower than normal. Always test spray to determine if the tobacco is mature enough to respond to treatmentwith ETHREl®. Apply over-the-top ETHREl® spray as a fine mist using three nozzles (one nozzle tip over the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similar to the application pattern ofsystemicsucker control a!."lents. Use aspray pressureof40 to 60 psi.


### USE LIMITATIONS Do not apply ETHREl ® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality.
Do not allow the crop to over ripen in the field after using ETHREL ® brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do not treat before antiCipated major storm which could prevent harvestand result in crop loss. Do not apply ETHREl®brand Ethephon Plant Regulator ifrain is expected within 6 hours.
Do not harvest tobacco treated with ETHREl ® brand Ethephon Plant Regulatorsoonerthan 2days after application. Follow use rates listed above for labeled uses. Do not exceed 8 pints ofthis product (2 Ib ethephon) peracre per year. 

### APPLICATION TIMING Successful results with ETHREL® brand Ethephon Plant Regulator cal! for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the proper treatmenttiming and the number of leaves per stalk ready for harvest, test spray several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves thatfail to yellow in 72 hours are not mature and are not ready for ETHRELlID treatment. Wait a few days to permit further natural maturing, then makeanothertestspray or "maturity" check. Determine acres to treat by first confirming the numberofleaves per plantthatwill color, then use barn capacity to calculate the number ofacres to treat. A test spray can be prepared by mixing 4 teaspoons of ETHREL® brand Ethephon Plant Regulator in 1 quart ofwater. Apply about 1 ounce to each test plantcovering all leaves with afine mist. ETHREl®will not color immature leaves. To avoid quality loss and/or possible leafdrop, harvest any yellowed leaves pr"lor to application. Use lower rates under most conditions. Limit use ofhigher rates to cool (below 65cF at the time oftreatment) slow ripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREL® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leaves have reached the desired color intensity.

14

# WALNUTS
WALNUTS IN CALIFORNIA: A foliar spray of

### ETHREl 

### ® brand Ethephon Plant Regulatorwill loosen walnuts for increased efficiency of mechanical halVest, promote earlier halV8st, improve hull removal, and increase recoverable yields from a once-over harvest. 

### Crop 

## ETHREL® Specific Directions Situation Pints/Acre Expect best results with spray concentrations of California 

### 3-5 300 to 

### 900 ppm. 

### Refer to spray 

### ETHREL® preparation chart below. Under low 

### temperatures and/or low humidity conditions use the higher label rates. Expect less time between application and harvest with higher label rates. For best results treat when airtemperatures are between 60QF 

### aod 95°F. Expect reduced effectiveness if above 90°F with low humidity due to sprayevaporation. Thorough uniform coverage of walnut hulls is essential foe maximum hull split 

### aod 

# 00' loosening response. Choose equipment that provides maximum spray penetration of the entire tree canopy. 

### Ure large air carrier sprayers where tree sizejeopardizes coverage. Orvolute sprayerattachments may help.



### USE LIMITATIONS Treatment priorto packing tissue brown (mature) stage may reduce nut quality. Some leafdrop is associatedwith treatment. Remarks Walnuts 

### are mature when the packing tissue between kernel halves completes browning. 

### Collect nut samples from throughout the tree canopywhen determining percent nut maturity. Advancing HalVes!

- Apply when 95-100% ofthe nuts have reached maturity. Inspect frequently 

### aod halVest 

### a, soon 

### a, adequate hullability occurs generally 10-16 days after treatment depending on variety and weather conditions. Plan second shake 10-12 days afterfirst shake. Once Over HalVest

- Variety, grOwing conditions and weather affect maturity and the opportunity for once over halVes!. Contact a local fieldman or Farm Advisor to determine if once over halVest 

### oao be expected 

# '0 your situation. Apply 

# '0 mature walnuts 10 days prior to expected halVest date. Expect actual harvest to range from 7-12 days after treatment.

Do not treat diseased, lowvigoror moisture stressed trees as excessive leafdrop may occur. Assure that dosage rates are measured accurately since rates higher than recommended may result in tree injury (such as excessivedefoliation, reduced catkin formation and twig dieback). Do not halVestwalnuts treated with ETHREL®soonerthan 5 days after lastapplication. Do not exceed 5 pints ofthis product (1.25Ib ethephon) peracre peryear.

ETHREL® SPRAY PREPARATION CHART SQray y-olume (gallonsfacre) ETHREL® Rate 

### 100 200 300 400 Pints/A Lbs/A Concentration (ppm) 

### 3 0.75 

### 900 450 300 4 1.00 

# - 600 400 300 5 1.25



## -- 750 500 375 500



# ---

--- 300

17

# MISTLETOE REMOVAL
DWARF AND LEAFY MISTLETOE REMOVAL: A foliar spray of ETHREL® brand Ethephon Plant Regulator will remove dwarf mistletoe shoots in ornamental conifers and leafy mistletoe from ornamental deciduous trees.

ETHREL® 

### Crop Situation Amount DWARF 

### 2 pints 

### MISTLETOE ON pee 

## ORNAMENTAL 20 gallons CONIFERS DOUGLAS FIR 

### 1 pint 

### ORNAMENTALS pee 

### 20 gallons

LEAFY 2 quarts MISTLETOE pee 

### ON 20 gallons ORNAMENTAL DECIDUOUS TREES 

### Specific Directions Remarks 

### Apply as a foliar spray to dwarf Applications made in conjunction with sylviculluraI mistletoe shoots before mistletoe mistletoe management will prevent spread of the seed dispersal. Foe effective 

### mistletoe parasite to other parts of the tree and removal, all mistletoe shoots must othertrees. 

### be sprayed to wet. Use of a non- Mature needle drop, that normally occurs in the ionic surfactant at 

### recommended fall, may be hastened by the use ofETHREL ®. 

### rates may increase effectiveness, Treat any m'lstietoe regrowth before Applications of higher rates on Douglas fir may seed dispersal. result in excessive needle drop. Make applications afterfall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. Foe 

### effective mesquite may be difficult to control 'Nith a single removal, all mistletoe shoots must application and retreatment maybe necessal)'. be sprayed to wet. Use of a nonionic surfactant at 

### recommended rates may increase effectiveness. Any mistletoe regrowth should be treated during the labeled application window.


# FRUIT ELIMINATION (Ornamental Use Only)
UNDESIRABLE FRUIT ELIMINATION: A foliar spray of ETHREL® brand Ethephon Plant Regulator will reduce or eliminate undesirable fruit development on apple, crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8to 12 ounces Apply as a foliar spray at the flower Application must be made before fruit set for best CRABAPPLES pee 

### bud to full bloom stage, prior to fruit results. set. Wet foliage thoroughly. Over Do not treat weak trees or trees under stress 20 gallons application of 

### ETHREL® Plant (drought, insect or disease damaged trees) as Do notexceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result. ounces (0.15 oz. leaf drop andlor 

### tree defonation,

ai/gallon) per Use 

### higher rates when Some leaf drop or temporary leaf yellowing may application. temperatures are cool. occurafter treatment. CAROB 6 ounces Apply as a foliar spray. Wet all Do 

### not use on small 

# ce' fruited varieties of (Cera{onia si/iqua) pee 

### foliage thoroughly. Amount of spray crabapple as 

### fruit elimination will 'ot be 

### 20 Qallons will depend on tree size. satisfactol)'.
OLIVE' 12 ounces (Olea europaea) pee 

### 20 Qallons "This recommendation is not intended to be used on commercial fruit production as a thinning agent.

18

# TURF

An application of Ethrel slows the growth ofturfgrasses thus reducing the required frequency ofmowing and the volume ofclippings collected.



### SITES 

## RATE APPLICATION SPRAY VOLUME Fairways, Roughs & Commercial 6 fl 

### ozi 1,000sq

### ft Apply

### to activelygrowing turf. Itwill 

### 0.5-4.0 9als/1,000 

### sq ft Turfgrasses, including Bentgrass require

### 7-10 daysfor ETHREL®to (Fairway cut), Kentucky 

### act Reapplication intervals: Bluegrass, Perennial Ryegrass, 

### Kentucky Bluegrass-7 wks. Tall 

### & Fine Fescue Perennial Ryegrass-7 wks. TalifFine Fescue-4 wks. 

### BentQrass-4 wks.


### Use Limitations:

Do not allowentry to treated areas unfll sprays havedried. For best results, applywith sprayer in sufficient volume ofwaterto provide uniform coverage. ETHREL® is foliarly absorbed. Apply only to activelygrowing turf, underfavorable growing conditions, that is notgoing into a dormancy period. Do nottreatturfgrass with poor root systems or growing understress dueto poorsoil conditions, drought, disease orinsectdamage. Do notapply togolfcourse greens. Use ofspreadersfstickers with ETHREL®is not necessary. ETHREL® is an acidic product and prolonged exposure to spray deposits will damage acrylic plastics, certain paints and metals. Rinse thoroughly all exposed acrylic plastic materials and painted surfaceswith a detergent and waterwithin one hour after exposure to spraydeposits.
Testtankmixes with other products on a small area before using widely.

19

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer ofWarranties and Limitations of liability before using this product. If terms are not acceptable. return the unopened product containerat once. By using this product, user or buyeraccepts the following Conditions, Disclaimer ofWarranties and Limitations of Liability. 

### CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it 

### is impossible to eliminate all risks associated with the use ofthis product. Crop injury. ineffectiveness or other unintended consequences may result because ofsuch factors as weatherconditions, presence ofother materials, orthe manner of use or application, all ofwhich are beyond the control of Bayer CropScience LP. All such risks shall be assumed bythe userorbuyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE LP'S ELECTION, THE REPLACEMENT OF PRODUCT.



# NET CONTENTS:

ETHREL is a registered trademark of Bayer.

Produced for

# ~b BayerCropScience

Bayer CropScience P.O. Box 12014, 2 T.W. Alexander Drive Research Triangle Park, North Carolina 27709

ETHREL ® brand Ethephon Plant Regulator (Pending) 01/20/10, Resubmitted 06/02/10

20, D:**Cfos~a;'** : D: CfostJd, 319050; 264-267;676;PmrilJct

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. D: Closed; 33581; 264-2$7;300;[4BEL**REI/f~**

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### D: Pending; 33572; 264-267,'320;DA TA REO( 

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# FungicideBranchAssignmentSheet


# 1

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# DateDe Iveredte'PM ,? h / j 

### 12 

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Commentsto Summer 

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Comments to RiskManager

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Dateto Summer 

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### initial) 

# Dateto RiskManager (d,testamp & 

### miti,l "''''below)

# Bayer

January 27,2010
DocumentProcessingDesk(AMEND) OfficeofPesticidePrograms(7504P) U.S. EnvironmentalProtectionAgency Room 

## SR4900, One Potomac Yard 2777 South Crystal Drive Arlington,VA22202-4501
Attn: Mr.TonyKish (PM22) Subject: ETHRELbrandEthephonPlantRegulator (EPAReg. No. 264-267) Amendmentto addpineapple and sugarcane
Dear

## Mr. Kish: Bayer CropScience is submitting an amended ETHREL brand Ethephon Plant Regulator (EPA Reg. No. 264-267) label with the addition ofpineapple and sugarcane uses which are already approved for ElliREL brand Ethephon Plant Growth Regulator For pineapple and Sugarcane (EPA Reg. No. 264-257). These two are similarformulations except for the concentration ofthe 

## active ingredient, ethephon. EPA Reg. No.**264~257** 

## contains 4 pounds ethephonlgallon, whereas, EPA Reg. No. 264-267 contains 2 pOWlds ethepbonfgallon. Appropriate rate adjustments are made to keep the maximum use rate for both pineapple and sugarcane crops unchangedonthe 264-267 label.
All the previously approved crops onEPA Reg. No. 264-267 label are arranged in alphabetical orderfor easeofuse.
Thefollowing documentsare attachedwiththis submission:
1.**~ication** 

## for Pesticide (EPAForm8570-1) 2. copies ofthe amended ETHREL brand Ethephon Plant Regulator label with the fIrst copyshowingthe changeshighligbted 3. One copy of the ETHREL brand Ethephon Plant Growth Regulator For pineapple and Sugarcane (EPA Reg. No. 264-257) label for easyreference
If you should have any questions or need further information, please contact me at (919) 549-2302.

SiITlYyours,

# -~ OZ-;""C'-c

# 0 PrasadRao RegistrationManager e-mail: pr3sad.raoul:;bavcrcropscicncc.com

P.O. Box 12014 2T.W. AlexanderDrive, Research TrianglePark, NC 27709 (919)**549~2000**, 

### No. "n70-oo8t "'" ,MM5 

### PI

__ ."IM**_,.v.n.~** , m, 

### Fonn Approvod. I United States

# ~ Registration OPP Identifier Number 

# &EPA Environmental Protection Agency ,f 

## Amendment Weshington. DC 20460 

## Other Application for Pesticide

- Section I
1. CompanylProduct Number 

### 2. EPA ProductMenaoer 3. Proposed Classification 

## 264-267 Mr. Tony Kish 

# o None 

# o Restricted 4. Compony/Product (Name) 

### PM'



### ETHREL brand Ethephon Plant Regulator 

## 22 5. Name and Address of Applicant (Include ZIP Coda( 

## 6. Expedited Reveiw. In accotdance with FIFRA Section 3Ic)(3) 

## Bayer CropScience (b)(n, my ptoduct is similat oridentical in composition and labeling 

## 2 T. W. Alexander Drive to: 

## Research Triangle Park, NC27709 EPA Reg. No. 

# oCh.ck if

### this 

### is II

### n8Wsddress 

### Product Name 

## Section

- II 

# (2] Amendment

- Explain bolow. 

# U Final printed lebals in fepsonse to Agency letterdeted 

# D Resubmission in response to Agllncy letter detlld 

# D -Me Too- Application. 

# D Notification· Explain billow. 

# D Othllr· Explain below.
Explanation: Use additional pege(s) if necllssary. tFor sllction I end Section II.) Addition ofalready approved uses of pineapple and sugarcane usesfrom ETHREL brand Ethephon Plant Growth Regulator

### For pineapple and Sugarcane (EPA Reg. No. 264-257}to ETHREL brand Ethephon Plant Regulator (EPA Reg. No. 264--267) label. These two aresimilarformulations exceptfor the concentration ofthe active ingredient, ethephon. EPA Reg. No. 264-257 contains 4 pounds ethephon/gallon, and EPA Reg. No. 264-267 contains 2 pounds ethephon/gallon. Appropriate rate adjustments are madeto keep the maximum use rate for both pineapple and sugarcane crops unchanged on the 264-267 label. Sincethese proposed label amendments do not require a review ofdata, no PRIAfee is required. 

## Section

- III
1. Matoriaf Th;' Product Will Be Packagod In: Child-Resistant Peckaging Unit Packaging Water Solubla Packaging 

### 2. Typa of Container

# ~y"**~y"**

# ~ y., [;] Mot.' 

## .f No 

## .f No ,f Plastic No Glass 

## * Certification must If -Yos- No. per If -Yes- No. per Papar Unit Packaging wgt. container Package wgt containar Other tSpecify) 

## btlsubmitted 

# , 3. Location of Net Contents Information 4. Sile(s) Rlltail Container 5. Location of Lebel Directions



# [{j Label 

# U Containor 

### 1 and 

### 2.5 gallons 

# t=::l

6. Manner in Which Lebel is Affixed to Product

# ['~-'l**~:~~~e~** 

# 0 Other Stond ad

## Section

- IV
1. Contact Point (Comp/MII ittlTnS dirtlctlybillowfor idtlnfification ofindividuel to b. contllctlld, ifntlctl$$lIIY, to

### proCI1S$ this (lJ)plication./ N
__ TItle Telephone No. (Include Alea Code) Prasad Rao Registration Manager (919) 549-2302

Certification £I. Oet(' Applicetion I cenify that the statements I have made on this form and afl attachments thereto are true, accurata and CtrTj::!ct?, Aecitived I ecknowladge that any knowlinglly falso or misleading statement may be punishable by tine or imprisorvn

..nt**~r** 

### (Stamped) both under applicable lew. 

### ""--

# 2'S;'O""~ 3. TItle 

# ·d**~cw** Registration Manager



# -

--- 4. Typed Nume 5. Dato Ptasad Rao 

## January 27,2010

" EPA Form 8570-1 IRov. 3-941 PreVIous editions are obsolete. , ' , 

### Whit••EPA File Copy longmal)

# UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHiNGTON, D.C. 20460



# NoV I R 20DZ

PrasadRao AventisCropSciencc 

## 2T.W. AlexanderDrive ResearchTrianglePark,NorthCarolina 27709 

## Subject:

DearMr. Rao, Ethrel®brandEthephon PlantGrowthRegulator EPA RegistrationNo. 264-257 ,/' Your label amendmentapplication dated August 12, 2002 OFFICEOF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES



## Theamended labelingreferred toabove, submittedinconnection withregistration 

## undel theFederal Insecticide, FungicideandRodenticideAct (FIFRA), as amended is acceptable, provided that you comply with the following conditions.


## I. You must makethe following changesto the label:

a, In the "IF IN EYES:" subsectionofthe "FIRSTAID" section, in 

## the second statement add 

## "eye" after "then continue rinsing".
b. inthe first sentence in the "I'ERSONAL PROTECTIVEEQUIPMENT(PPE)" section. add "made ofanywaterproofmaterial" after "chemical resistant gloves".

e. III the first scntence inthe**seeond-to~last**

## paragraph inthe "AGRICULTURALUSE REQUIREMENTS" section,change "chemical resistantgloves suchasany waterproofgloves" to "chemical resistant glovesmadeofany watelvroofmaterial, suchas nitrile, butyl,neoprene, or barrierlaminate".
2. Submitonecopy ofyotn'final printed labelingbefore you release the productfor shipmcnt.

Ifthcse conditionsarc not complied with, theregistration may be subjectto canccllation inaccordance withFIFRA section 6(e). Yourrelease for shipmentoftheproductbcaringthe amended labeling constitutes acceptance ofthese conditions.

# .'

Ifyou 

## have anyquestions ahout this letter, please contactJohn Bazuin at (703)305-7381.

Sincerelyyours, 

# (5/ CynthiaL. Giles-Parker Productl1anager(22) 

## Fungicide Branch RegistrationDivision (7S0SC)



## Altaclnnent: Label stamped "ACCEPTED with COl1l1ENTS"

# • 

# ETHREL brand Ethephon Plant Growth Regulator For Pineapple and Sugarcane FOR COMMERCfAlORAGRICULTURALUSEONLY. NOT FOR RESIDENTIAL USE For Flowerinduction andMaturityConcentration in Pineapple 

## ForFlowerPreventionandBiomassIncreaseIn Sugarcane (Hawaii Only) ArriVE INGREDIENT:



## Ethephon ((2-chloroethyl) phospltonicaddJ*

.....................................................................................................................................39.9% INERT J

### NGREOIENTS:

...........................................................................,..................................,.''''

...."

...................................................60.t% 

## *This product(ontains4 pounds ethephonpergallon. 

## EPA Reg. No. 264-257 EPA 

# Est. No. 264-PA-Ol 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

si usled noenliendeIiietiqucta. busque it

### algu;en paraque5ela explique it

### usted

## en delalle. (If

### you donotunderstand 

### thelabel. find someonetoexplain it

### toyou in detail.) For MEDJCAL And TRANSPORTATION Emergencies**~**

### call 24 HoursA Day 1-800-334-7577 For PRQDUa!!.Sf 

### Information call1·888·AVENTIS

### (1-888-283-6B47) 

### The use oj this product lor a variety 01 plant growth regulation usc\ is (overed by United Stales and foreign palents including 

### U.S. Palent'1,240,8t9. No licenseisgrantedto usethis productin countriesothertllan tile United Statesorfor anyuse notcontemplated byIllislabel. liabilityforpalentiniringementmayresult fromuseorsaleofthisproductoutsidethe UnitedStales. 

## FIRSTAID IfIN EYES: 

# • Holdeyeopenand rinseslowlyand gentlywltbwaterfor 15·20minutes. 

# • Removecontactlenses, Ifpresent,afterthefirst 5**mir1Ut~,** 

### thencontinuerinsing. 

# • callapolsoncontrolcenterordoctorfortleatmentadvice. tFSWALLOWED: 

# • ImmediatelycallapoiSOil

### controlcenterord'pctorfortreatmentadvice. 

# • DolIotinducevomitingunlesstoldtodo so byapoisoncontrolcenterordoctor. 

# • lIave person sipaglassofwaterjfableto swallow. 

# • DonotRiveanythingby'mouthto an unconsdousperson.



# -- IFONSKIN OR 

# • Takeoffcontaminatedclothing. (LonIlNG: 

### Rinseskinimmediatelywith plentyof

### waterf(,lr 15·20minutes. 

# • • callaDOisoncontrol centerordDctorfortreatmentadvice. ForMEDICAL**Em~rgencies**

### CaU24

# li'qurs:A

# Qav 1-800-334-7577. Havethe (!:roductcontainerorlabelwlth youwhenOlUinSapolson controlcenterordoctororsoinSfortleatment. NOTETO PHYSICIAN; 

### Treat5)'f1lptomatiOllly. Considerationshould begiVentothepossibilitythatoverexposuretomaterialsotherthan**thi~** 

### I uroduct meWhaveoccurred. No specificantidoteisavailable. Probable mucosaldamagemay

### contraindicatetheuseofs<astriclavaRe, 

## PRECAUTIONARY STATEMENTS DANGER HAZARDSTO HUMANS AND DOMESTICANIMALS Corrosive. Causesirreversible eye damageand skin irritation. clothing. Harmful ifswallowed or absorbedthrough the skin. 1"10 

### nnt getin eyes, on skin, or on

. 

# . 

# . . PERSONAL PROTECTIVE EQUIPMENT (PPEj Applicatorsand other**h~ndlers** 

### must wear long·sleeved sllirts alld long pants, dlemical resistant gloves (such as Nitrile, Butyl, Neop'I'''':**~nd/OJ** 

### Barrier Laminate), shoesI1ll1ssocksandprotectiveeyewear.

### when Ilamtlersuseclosed syslems, enclosed cabs, or aircraft in a manner Ihat meelstherequirementslisted in the Worker Prolection Slandarsl (WPS) 

### for agriculluralpesticides [40CFR 170.240(d) (H)],

### thehandler PPErequirementsmaybe

### reduced ormodiliedas spedfiedIntheWPS.

- Discard clothingand other absorbentmaterrals Ihathave been drenched orheavtly conlaminated with this productsconcenlrate. 00 not reuse them. f'(lilow mauulaclurer's instructions lorcleaning/maintaining PPE. II no such instructions forwashables, usedetergentand hotwater. Keep and wash PPEseparately from olherlaundry.


# UserSafelyRecommendations Users SllOUldwashIrandsbeloreealing,drinking, cllewinggum, usingtobaccoorusing thetoilet. Users shouldremoveclolhingimmediatelyil pesticidegetsinside. Then wash

### bodythoroughlyand puton cleanclolhlng. Users shold remove PPE immedialelyaller handling Uris product. As won 

### as possible, wash thoroughly and change into clean clolhing. Wash !he outside

### ~i;lovesbelore removinit.- 

## ENVIRONMENTAL HAZARDS Do notapply directly to water, orto areas wlrere surfacewater is presentor to intertidal areas below the mean high waler mark. Donotcontaminale waterwhen disposingofequipmentwashwalers. Do notconlaminatewaterusedforirrigalion ordomestic purposes. 

## SPRAY DRIFT Avoidspraydrift. 00 notapplywhen weather conditionsmaycausedrift. Do notallowthis product to drifton to non·targel areas. Drift mayresult in illegal residues or injury to adjacent crops and vegelation. in the lorm of leal yellowing and deloHation. To avoid spraydrift, DO NOTapply aerially when wind speed rsgrealerthan 10mrfl orduring periods01temperalureinversions. Use01larger droplel sizewill alsoreducespraydrift. WOIOING SPRAYDRIFfATTHEAPPLICATIONSITEISTHERESPONSIBILITYDFTHEAPPLICATOR. ,he interaction 01 many cquipment-and·weather·relatedlaclors determine the potenlial for spraydrift The applicatoris responsible lor considering all thesefaclors when makingdecisions. The following drilt management requirements must be lollowed 10 avoid off-target movement Irom aerial applications to agricultural lield crops. Theserequirementsdonolapplyto foreslry applications,public health uses or**t~pplications**

### using dryformulations. I. TIledistance01the outer moslnouleson Iheboom musl notexceed 3/4 thelength ollhewingspan orrOlor. 2. NOlZler must alwayspointbackwardparallelwilh theair streamand never

## bepointeddownwards morethan 45degrees. Where slates havemore stringentregulalions, Ihey shouldbeobserved. Theapplicatorshould be lamiliarwilh andtake into accounl theinformationcovered in theAerial Drilt ReductionAdvisorybelow: 

## AERIAL DRIFTREDUCTION ADVISORY [This section isadvisoryinnalureand does notsupersedethe mandalory label requirements]. INFORMAYION ON DROPLETSIZE 

### The mosl eilective wayto reduce drift potential is to apply large droplels. The besl drill management strategy is to apply tile largest droplet$ that provide suflicientcoverageand

### conlrol. Applying larger dropletsreduces driltpotential, butwill not preventdrift ifapplications aremadeimproperly. or under unlavorableenvironmental conditions (SeeWind,TemperatureandHumidity, andTemperatureInversions). CONTROLLINGDROPLfTSIZE



### olume

-Use high flow rate nozzles10applyIhehigllest practical SlJrayvolume. Nozzleswith Iligherrated flows produce largerdropleis. Pressure· Do notexceed Ihe nozzle manufacturer's recommended pressures. For many nozzletypes lower pressure produces larger droplets. Wilen higher flow rates areneeded. use higherflowrate nozzlesinslead ofincreaSingpressure. Number ofnozzles· Usethe minimum number01nozzlesdratprovideuniform coverage. Nozzle Orientation· Orientingnozzles soUral the spray isreleased parallel to theairstream produces largerdroplets than other orientarions and is the recommendedpractice. Signrlicantdeflectionfrom Irorizontalwill reducedropletsizeandincreasedrlltpoteutiaL NoaleType· Usea nOl'.7.lctype Ihal is designed lor lile intended application. With most noaletypes, narrower sprayangles produce larger drorlets. Considerusinglow·drilt l\Oules. Solid stream noale$oriented straightbackproducethe largestdroplets and the lowesl drift. BOOM LENGTH 

### For some use**II~tlerns.** 

### reducing the elleclive boom le"glh to less thau 3/4 

### 01 thewingspan orrotor length mayIUrt/lerreduce !hiltwiUwut reducing swaUI width. APPlICAnON HEIGHT 

## , Allplications should nol bemadeal aheiglltgrealerUlan 10leel above thetop01tile target

## ~antsunless agrealer lreighl b

## requir~d lor aircraft foiIlely. Makingapplicationsalthe lo\vest heighlthai IS salereducesexposure01droplets toevaporationandwind. ••
. .'

. SWATH ADJUSTMENT Wilen applications are made Wftll a crosswind, the swatll 

### will be displaced downwind. Tllerelore, on Ille rip ano' dl"wnr'ind edges'olille lield. the ,lpplicator should comr,ensale lor Ihis displacemeut by adjusling Ihe palh of Ihe aircraft upwind. Swath**adjustm~'lt** 

### <ji$.ance should increase. willI increasingdrilt potential(higherwind, smallerdrops. etc.).

### WIND



# . Drift potential is lowest between wind speeds oil

- 10 mph. However, many factors, including droplet sile and equipment type determine drift pOlential atanygiven speed. Application should beavoided below 2mph due to variablewind dirertion and high inversion potential.**~OTE:** 

### local terrain can influencewindpatterns. Everyapplicatorshould befamiliarwith local wind patternsand howtheyaffectspraydrift. TEMPERATUREAND HUMIDITY 

### When maldngapplicationsinlow relativehumidity, set up equipmentto producelargerdroplets to compensatefor evaporation. Dropletevaporation ismostseverewhenconditionsare both hotanddry. TEMPERATURE INV£RSION5 

### Applications should notoccurduring

### atemperature inversion becausedrift potential ishigh. Temperatureinversionsrestrict vertical airmixing, which causes small suspended dropletsto remain in a concentrated cloud. This cloud can move in unpredictable directions due to the light variablewinds common duringinversions. Temperature inversionsarecharacterized byincreasingtemperatureswithaltitudeand arccommon on nightswith limited cloudcoverand light to no

### wirkl. Theybesinto form as the sun setsand often continue into the morning. Their prtsencecan beindicated byground log; however, iffog is not present, inversionscan also be identilied by the movement

### ofsmokefrom 

### aground source or an aircraft smoke generator. 

### Sm[)ke that layersand moves laterallyin aconcentlatedcloud(underlowwindcondilions)indicatesan inversion, while smoke that movesUpWardand rapidlydissipatesindicatesgood vertical airmiKing. SENSITIVEAREAS 

### The pesticide should only be applied when the potential for drillto adiacentsensitiveartas

### (e.g. residential areas, bodies ofwater, known habitat lor tlueatened orendangered species, non·targetcrops)isminimal (e.g.when wind isblowingawayfrom thesensitiveareas). 

# DIRECTIONS FOR USE IIh 

### aviolationofFederal Law 

### to use thisproduct In

### a mannerInconststenlwith III labeling. D[) 

### notapplythhproduct In a 

### way thatwill contact workers orotherpersons.eitherdirectlyorthrough drift. onlyprotected handlers may beIn theareaduringapplication. Foranyrequirementsspecifictoyour5taleorTribe.consulttheagentyresponsibleforpe5tldde regulations. Readentirelabelbefore usln,this product,

. 

## , 

## AGRICULTURAL USE REQUIREMENTS USC 

### this product only in accordance with its labeling andwith the Worker Protection Standard, 40 (FR 

### part 170. 

### This standard contains requirements lor the protection 01 

### agricultural workers on farms, forests, nurseries, and greenhouses, and handleri of agricultural pesticides. II 

### contains requirements for tmining, de<Ontamination, notification, and emergencyassistance. II

### also contains specific instructions and exceptions pertaining to tbe statementson this label about personal protective equipment (PPj:), 

### notification to workersand restricted·entryintervals. Therequirements in this boxOldyapplytouses ofthis productthatarecovered bytheWorkerProtection Standud. 00 

### not enteror allow worker entry into treated areas during the restricted·entryinterval (REI)

### of48 

### hours. The REI 

### is 72 

### hours inareas where average rainfall is lessthan 2S inrhesperyear. prE required forearlyentryto treated areas that is permitted under theWorker Prote<tion Standard and that involves contact 

### .....-ith anything that has been treated such as plants, soil 

### or water is coveralls OVei long-sleeved shirtand long pants. chemical resistanl gloves such as any waterprool gloves, chemical resistantfootwearpillSsocks, and protectivecyewear. roroverheadexposure, chemical·resistantheadgear is also required.**~otily**

### workers

### 01theapplication by**warnin~**

### themorallyand nostinRwarniml.siRnsatentrancestotreatedareas. 

## ,MPORTANT Do not use this product lor purposes other than those listed on the label. 00 

### not eKceed the rate of ETHREL- 

### brand Ethephon per acre per year recommendedonthislabel. Donotapply ETHREL- 

### brand £thephon throughanytype 01 

### irrisationsystem. 

## ACCEPTED 

# wi'" COMMENTS InEPA

## LoltorDated.



# . NOV I 8 alU2 Under she 

### Faderal**rJllfleUcl~e,.** 

### Funaicldc, 

### ud 

### ROOOlllkide 

### AeIJ M Ilmllnded, for Ihft pelU(tdc. ; hIls!.lf:red WIder EPA 

### Reg. No. • 

# ...

# .

# . .
. 

# . •



# . .

--

# . 

# ..

. 

# .

." 

# .. •



# . 

# .
.

# STORAGEAND DISPOSAL STORAGE 

### 00 not contaminate

### waler, 'Dod, orleed by storageordisposal. PESTICIDEDISPOSAL 

### Pesticide waSles are hazardous. 00 not contaminatewater, food. orfeed by

### storageor disposal. Improper**djspo~1** 

### ofexcess pesticide. spray miJ.;ture, 

### or rinsate is aviolation 01 Federal law. II thest! wastestannot be disposed 01 by use according to label instructions. (ontact your State '>esticide or EnvironmentalControlAgencyortheHazardousWaste representativeatthenearestEPARegional Officeforguidance. CONTAINERDISPOSAL 

### Triple rinse(orequivalent), Then offerlor recyclingorreconditioning, orpunctureand disposeofinasanitarylandlill. by rncineration or

### ifallowt!d by slateand localauthorities. by open burning. II burned. stayout ofsmoke, 

## GENERAL INFORMATION When fTHREla

### brand fthephon Plant Growth Regulator lor Pineapple and Sugarcane is applied to plants. the product decomposes within the plant tissueto releaseethylene, anaturallyoccurringplanthormone. PINEAPPLEflOWER fNDUCTION 

### ApplicationofETHREt.'brand Ethephonwillinduceuniform flower initiation ofpineappleplants. PINEAPPLEMATURfTYCONCENTRATfON



### pplicationofETHRELfIbrand Ethepllonwill stimulateuniformshell color ofpineapplefruit. SUGARCANE flOWER PREVENTION 

### A

foliar sprayofETHREl·brand Ethephonwill reduceorpreventfloweringofsugarcane. SUGARCANE BIOMASS INCREASE 

### fTHREl· brand Ethephonapplication topreventfloweringcan result in increased"bromassaccumulationand increased re<overabie sugars. For recommendations on rates, spray volumes, and spray equipment under varying temperature and rainfall conditions consult your Extension sperialisl, AvenHsCropScienc:e Representativeor larmagronomist for hisexperierl(cwiththis productin yourarea. SPRAYPREPARATION 

### Add tl2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required ilmOllnt ofETHREl· brand Ethephon. and the remaining amount ofwater. Prepare only as much spraysolution as can be**u~** 

### on the dayofmixins. US(! 01 previous day's spray mix may result in reduced activi!y. Do notspillthecOflcentratedproducton sprayequipment. orany airplaneparts. ANY

### SPillSSHOUt.D BE 

### IMMEDIATELYRINSEDWmt Plt.;NlYOfWATER AS ETHREl· brand Ethephon IS CORROSIVE. Use of a nurse tank is highly recommended lor avoiding possible spills ofconcentrated formulation on sprayequipment. EQUIPMENTCLEANtNG 

### Becauseoftheacidic nature ofthisproduct,prolonged**e~posure** 

### to spraydepositwilldamageacrylic piastics, certain paints and metals. qiust> thoroughly with detergent and water all exposed acrylic plastic-type materials (e.g. aireral!**windshields~** 

### and painted surfaces within an hour ,terexposureto spraydeposits. Attheend of each day, rinse thoroughly with detergent and water all metal parts of theaircraft and the associated spray equipment**e~posed** 

### to the spray deposits.



# .,

# .

### (ROPAND 

### RATE PER SPRAY 

### USE 

# "R' VOLUME APPLICATION TIMING 

### PINEAPPLE 

### FlowerInduction lto2quarts 100 10 500 'Bearing 

### age' 

### about 12 

### fTHREl-applied to gal/A 

### months after 

### planting, pineapple plants

### will Generally about 6 months stimulate UnifOlffl 

### priorto 

### desired ha

### rvest. initiationofflowering.

MaturityConcentration 1/1101 

### 10Dto300 

### When the first fruit begin to ETUREl· 

### applicationwill 

## quarts gallA chllngecolor. Slimulateuniformshell colordevelopment

SUGARCANE 

### FlowerPrevention 1pint 7gallA Justpriortoflowerinitiation. THREl- applicationwill 

### minimum preventorreduce Ilowelingaod pithy tissueformation. Biomass Increase 

# - ETHREL·USed to prevent lIowelingcan alsoresult in increasedbiomass accumutation and lC{ovcrablesugaryield. 

# 7**~ ~.** 



# -

- SPECIFICCOMMENTS RESTRICTIONS

Proper rate 

### will vary with 

### 00 not graze pineapple 

### local growing 

### conditions. forage treated 

### with ETHRElvarieties, plantation Do not halVesl 

### pineapples 

## management practices 

## "d treated with ETHREl- sooner time of year. 

### Use the higher than 2 days. allel the last 

### ralc where earlier harvest is application. desired. Apply 

### when 

### pinel!wle**foliag~**

### is**d~** 

### Use 

## a broadcast spray, 

### thoroughly coverboth fonage and fruit. Use

### the higherrate during periods of cool 

# " cloudy weather when normal ripen{1lJ/ hasslowed.
Apply by liKed wing 

# " Do 001 

### harvest sugarcane helicopter using equip'ment treated with ETHREl· sooner designed to 

### give unifolm than 1 

### months after the laSl ooverage. application. 

### Do not graze Actual biomass increase 

## will sugarcaneforage treated with 

### Ire affected by 

### the time ETHREl-. between treatment 

## "d harvest. Consider anticipated 

## recoverable sugars as well as biomass 10 

### determine QIltimum halVestdate. For Use

### In Hawaii Only.



# ... 

# ·

. 

# · .,

# .. • 

# ·
..... •



# .

.



# . • 

# ·
... • 

# ·

- 

# .

## IMPORTANT: READ BEFORE USE Read the entire Direclion5 for Use, conditions. Disclaimer ofWarranties and limitations of liability before uSing this product. If terms are. not acceptable.return theunopenedproductcontainerat Orlce. 

### Byusingthis product, lIscrorbuyeracceptsthefollowingConditions, DisclaimerofWarranties and Umitationsofliability. CONDITIONS:Thedirectionsforuseofthisproduct.Hebelievedtobeadequateand should befollowed

## carelully.However, it

### isimpossibletoeliminate all risks <l5sociated with the use ofthis product. Crop injury, ineffectivenessor other unintended consequences may result because ofsuch factors as weather condl\ioflS, presenceofothermaterials, orthe manner ofuse or application, allofwhich are btyond thecontrol of

### Aventis CropSdencc. All such risks shall be assumed by Ihe useror buyer. DISClAIMEROF WARRANTIES: AVENTIS (ROPSCIENCEMAKESNO OTHERWARRANTIES, EXPRESS OR IMPliED, OfMERCHANTABILITYOROF fITNESS FORA PARTICUlAR PURPOSEDROTHERWISE. THATEXTEND BEYONDTHESTATEMENTSMAOEONTHISLABEl. No agentofAventis (ropScience is authorized to**m~ke** 

### any waff3nties beyond those contained herein or to modify the warranties contained herein. AVENTIS CRDPSCIENCE DISCLAIMS ANY lIAllililY WHATSOEVERFORSPEGAL, INCIDENTALOR CONSEQUENTIAlOAMAGESRESULTING FROMTHEUSEORHANDUNGOFTHISPRODUG. liMITATIONS OFUI\tUlITY:THEEXCLUSIVE REMEDYOfTHEUSERORBUYERFORANYANDALL lOSSES, INJURIESORDAMAGESRESULTING FROMTHE USE OR HANDLINGOf THIS PRODUG, WHETHER IN CONTRAcr, WARRANTY, TORT, NEGLIGENCE. STRIG lIABIUlY OROTHERWISE, SHAll NDT EXCEED THE PUROiASEPRICEPAID,ORATAVENTlSCRDPSCIENCE'SHEatDN,THEREPlACEMENTOFPRODUG.



## NET CONTENTS: 1GALLON**Aventt~**

### CropSdence USA LP P.O. BOI{ 12014, 2T.W. Alel{ander DrIve ResearchTriangle Park. North carolina 27709 ETHRIl is aregistered trademark oftheAventis Group.
fTHRH· !lrandElheptlon Plant Growth Regulator lor rineappleandSugarcam: (PENDING) Submitted 7/17/02 

# .... '

# . • •• • •• • 

# • 

# ·

.....

• •



# .. '" ., 

## " 

# . 

# .. . • • 

# ...... • •

# ,.,

...., For use on Apples, Blackberries, Blueberries, Cantalg.u 5, 

## Cherries, Grapes, Peppers, Pineapple, Sugarcane, Tobacco, Tomatoes, Walnuts, anef"""for the removal of DwarfMistletoe in Ornamental Conifers and Leafy Mistletoe in Ornamental Deciduous Trees and for the elimination of undesirablefruit onApple, Crabapple, Carob, and Olivetrees. ACTIVE INGREDIENT: Ethephon [(2-chloroethyl)phosphonic acid]*

.......... ........................ ...................... ..... 21.7% INERT INGREDIENTS:

.................................. ...........................................................................................78.3% *Contains 2 pounds ethephon pergallon. 

## EPA Reg. No. 264-267 EPA Est. No. 264-PA-01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entiende la etiqueta, busque a alguien para que S8 la explique a usted en delalle. (If

### you do not understand the label, find someone to explain it to you in detail.) 

### ForMEDICALAnd TRANSPORTATION Emergencies ONLY Call 24 HoursA Day**1~800~334~7577** 

### For PRODUCT USE Infonnation

# Call1~888~AVENTJS**(1~888~283~6847) ~**  1:'0

# vf!!..-r-).- FIRSTAID

IF IN EYES: 

## • Hold eye open and rinse slowly and gentlywilh walerfor 15-20 minutes. 

# • Remove contact lenses, 

### ifpresent, after the first 5 minutes, then continue rinsing. 

# • Call a Doison control center ordoctorfortreatmentadvice. IF SWALLOWED: 

## • Immediately call a pOison control center or doctorfortreatmentadvice.


## • Do not induce vomlting unless told to do so by a poison control centeror doctor. 

# • Have person sip a glass ofwater ifable to swallow.


## • Do notgive anythinQ by mouth to an unconscious person. IFON SKIN OR 

## • Take offcontaminated clothing. CLOTHING: 

## • Rinse skin immediately with plenty ofwater for 15-20 minutes.


## • Call a pOison control centerordoctorfortreatmentadvice. IF INHALED: 

## • Move person to fresh air.


## • If person is not breathing. call 911 or an ambulance, then give artificial respiration. preferably mouth-tomouth ifpossible.


## • Call a poison control centerordoctorfor furthertreatmentadvice. For MEDICAL Emergencies Call 24 HoursA Day 1-800-334-7577. Have the product container or label with you when callina a poison control center ordoctororaoinq fortreatment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use of gastriC lavage. No specific antidote is available. All treatments should be based on observed signs and symptoms of distress in the patient. Overexposure to materials other than this product may have occurred. Victims 01 severe overexposure by inhalatlon should be kept under medical observation for up to 72 hours for delayed onset of pulmonary edema. In a victim of overexposure by ingestion. careful gastric lavage is required due to the possibility of stomach or esophageal perforation. This material is an acid. butthe use ofalkaline substances to neutralize it is contraindicated.

, ,

# . ., 

# . , ") 

### ,

# PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS Corrosive. Causes irreversible eye damage. Wearsafetygoggles when handling. Harmful Ifswallowed orabsorbed through skin. Do not getin eyes oron clothing. Avoid contactwith skin. Do not inhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials thatare chemical·resistantto this product are listed below. If you want more options, followthe instructions for Category A 

### on an EPA chemical-resistance selection 

### chart Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, shoes plus socks and protective eyewear. When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the reqUirements listed in the Worker Protection Standard for agricultural pesticides (WPS) [40 CFR 170.240 (d) (4-6)[. the handler PPE reqUirements may be reduced or modified as specified in theWPS. Discard clothing and other absorbentmaterials that have been drenched or heavily contaminated with this products concentrate. Do not reuse them. Follow manufacturer'S instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hot water. Keep andwash PPE separately from other laundry. 

## User Safety Recommendations Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into clean clothing. The contaminated clothing should bewashed before reuse. Users should remove PPE immediately after handling this product. 

### As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofgloves before removing. 

## ENVIRONMENTAL HAZARDS Do not applydirectly to water, orto areas where surface water is present orto intertidal areas belowthe mean high water marlc Do not contaminate waterwhen disposing ofequipmentwashwaters. 

# DIRECTIONS FOR USE It is a violation 

### ofFederal Law to usethis product in a manner inconsistentwith its labeling. Do notapply this product in away thatwill contactworkers orother persons, eitherdirectly or through drift. Only protected handlers may be in the area during application. For any requirements speCific to your State or Tribe, consult the agency responsible for pesticide regulations. Read entire label before using this product. 

# AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. 

### It contains requirements for training, decontamination, notification, and emergency assistance. It also contains speCific instructions and exceptions pertaining to the statements on this label <bout personal protective equipment (PPE), noflfication to workers, and restricted-entry intervals. The reqUirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches per year. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, chemical resistant footwear plus socks, and goggles orface shield. Foroverheadexposure, chemical-resistant headgearis also required. Notifyworkersofthe application bywarning them orally and by posting warning signs atentranceto treated areas.



## "
,

, , ;

... page'Zot'2C/ 

## "
, , } 

## , , } ) 

### , "

# PES~E STORAGE 

# STORAGE AND DISPOSAL

Do notcontaminate water, food, or feed by storage and disposal. PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of excess pestiCide, spray mixture, or rinsate is a violation of Federal Law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control

Wastes resulfmg from the use ofthis productmay be disposed ofon site or atan approved waste 

### d"lsposal facility. Agency orthe Hazardous Waste representative atthe nearest EPA Regional Office for guidance. 

# (.,...£de.,.ll

CONTAINER DISPOSAL ./ Rigid, Non-refillable containers sma!! enoughto shake (Le., with capacities equal to or!essthan 5 gallons)

## ~ . Non-refillable container. Do not reuse or refill this container. Offer for recycling, if available. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipmentor a mix tank 'and drain for 10seconds afterthe flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 10seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this proceduretwo more times. Then offer for recycling orreconditioning or puncture and dispose ofin a sanitarylandfill.
ETHREL 

### ® BRAND ETHEPHON PLANT REGULATOR Promotes earlier, uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increases dormantfruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower induction, pineapple maturity concentration, sugar\e flower prevention and biomass increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe fr ORNAMENTAL DECIDUOUS TREES. Eliminates undesirable fruit on APPLE, CRABAPPLE, CAROB, and OLIVE trees. 

# e.o1.

GENERAL INFORMATION (

# ~ 

# 1

For local recommendations on rates, spray volumes (gallons of water per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, HorticUltural Specialist, Bayer CropScience Representative or Farm Advisor for his experience with this product in yourarea. 

### APPLICATION VOLUMES AND SPRAY COVERAGE Thorough spray coverage is essential to achieve maximum product effectiveness. Spray coverage is affected by choice of equipment, nozzle selection and spray boom setup aswell as spray pressure, plant size and canopy density. Forboth air and ground applications, 

### it is important to choose an equipment setup that will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will varywith the size and density ofthe plant canopy and the equipment used. In California and Arizona use a volume ofno less than 5 gallons per acre for aerial applications. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do not contaminate waterused for irrigation ordomestic purposes. Avoid spraydrift to nearbycrops as this productwill cause modifications in plantgrowth. Plant injury or reduced yields will result. Do notplantanothercrop within 30days aftertreatment.

# ~DO NOT MIX ETHREL® WiTH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC 

## ,}rtf FUMES. 

# qJ1"\. [Add % to % of the required amount ofwater to the spray tank. Start agitation. Add the required amount of ETHREL® brand Ethephon 

## r "1.Plant Regulator. Mixonly the amount ofspray you expectto use each day. Do not allow mixed solution to stand overnight. Do notuse ETHREL ® brand Ethephon Plant Regulatorwith additives other than recommended on this label. Avoid spills ofconcentrated product on spray equipment or airplane parts. IMMEDIATELY RINSE ANY SPILLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. IMPORTANT: Do notapply ETHREL® brand Ethephon Plant Regulator through any type of irrigation system. Do notuse this productfor purposes otherthan those listed on the label. Do not exceed the rate ofETHREL ® brand Ethephon Plant Regulator per acre peryear recommended on this label. 

### " " 

## , ,



## , 

## .,
, yage3

### -Cf2')



### , 

## , ) ) 

### , ))

### SPRAY DRIFT**~** 

### Avoid spray d(lft. Do not apply when weather conditions may cause drift. Do not allow this product to drift onJo non·target areas. Drift may result in illegal residues or injuryto adjacent crops and vegetation, in the form ofleafyellowing and defoliation. To avoid spray drift, DO NOTapply aerially when wind speed is greaterthan 10 mph or during periods of temperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFTAT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weatheHelated factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management requirements must be followed to avoid off-target movement from ae(lal apprlcations to agricultural field crops. These requirements do not apply to forestry applications, public health uses orto applications using dry formulations. 1. The distance ofthe outer most nozzles on the boom must not exceed 3f4 

### the length ofthe wingspan orrotor. 2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. Where states have more stringent regulations, they should be observed. The applicatorshould be familiarwith and take into accountthe information covered in the Aerial Drift Reduction AdviSory below: 

## AERIAL DRIFT REDUCTION ADVISORY INFORMATION ON DROPLETSIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if appllcations are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and Temperature Inversions). CONTROLLING DROPLET SIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higherflow rate nozzles instead ofincreasing pressure. Numberofnozzles

- Use the minimum numberofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. Significantdeflection from horizontal will reduce droplet size and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce largerdroplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 3f4 

### of the wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEIGHT Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required for aircraftsafety. Making applications atthe lowest heightthat is safe reduces exposure ofdroplets toevaporation and wind. SWATH ADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adjusting the path ofthe aircraft upwind. Swath adjustment distance should increase, with increasing driftpotential (higherWind, smallerdrops, etc.). WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment 

### type determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and howthey affectspraydrift. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet evaporation is most severe when conditions are both hot and dry.

, 

### , " 

## "



## , " 

### ';" page4D120



### , " J , ,TEMPERATURE !NVERS!ONS App!ications should not occur during a temperature inversion because drift potentia! is high. Temperature inversions restrict vertical air mixing, which causes sma!! suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the fight variablewinds common during inversions. Temperature inversions are characterized by increasing temperatureswith altitude and are common on nights with limited cloud cover and fight to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves !ateraUy in a concentrated cloud (under row wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. SENS!T!VE AREAS The pesticide should only be applied when the potentia! for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, known habitat for threatened or endangered species, non-target crops) is minima! (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray deposits wi!! damage acrylic plastics, certain paints, and metals. Rinse thoroughly aU exposed acrylic-plastic materials and painted surfaces with a detergent and waterwithin one hour afterexposure to spray deposits.

Page 5 of20

# APPLES
APPLES: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples, making halVes! by 

### hand or machine easier and more efficient. ETHREL

### ® applied in combination with FRUITONE@ N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruil. Applied to young trees, ETHREL

### ® will suppress vegetative growth and promote flower bud formation.



### Crop Situation FRUIT LOOSENING
f. EARLY AND MIDSEASON MATURING VARIETIES (varieties maturing with Mcintosh or earlier)



### 2. LATE MATURING VARIETIES IN THE EASTERN UNITED STATES (varieties maturing later than Mcintosh) PROMOTION OF UNIFORM RIPENING AND COLORING OF RED VARIETIES WITHOUT LOOSENING ETHREL® Pints/Acre



### 2 112

5 Specific Directions Apply a foliar spray to apple trees 7 to 14 days priorto normal anticipated halVes!. Use sufficient water for thorough uniform spray coverage. The type**o~s**

### er used and size of trees will ffec' ) VOlfe 

### 'd 

### J:::. reqUIre , 

### 0\**~** 

# T e C/ 

### Observe fruit daily as the proper picking period is shorter with ETHREL® treated fruit than untreated fruit Do not exceed 

### 1.25 pounds ailA per season.

Apply foliar spray of 

### ETHREl ® 

### and a prehalYest drop control chemical registered fOr use on apples such as the 

### product FRUITONE® N. Use the prehaIY8st drop control product according to label d'irections. Begin spray'lng 2 to 3 weeks before normal halVes! period and 

### about 1 

### to 2 weeks before desired halVestdate. 1. EARLYOR 1-4 MIDSEASON Apply as a normal dilute spray using MATURING sufficient water for thorough uniform VARIETIES coverage, Actual volume will depend on (varieties the type of delivery of sprayer used and maturing with size oftrees. Mcintosh or Use the lower rate for apples intended for f--....::ec"'cn:ecO'---

___

# + _____-i storage. 

### 2. LATE MATURING VARIETIES (varieties maturing later than Mcintosh) 

### 2-4 Do not exceed 

### 1.25 pounds ai/A per season. Remarks 

### ETHREL® 

### provides several beneficial responses on apples, Depending on rate and time of application ETHREL®will: promote fruit loosening, promote uniform ripening and coloring wlthout loosening, promote thinning and return bloom, and increase flower bud development in young trees. Fordesired response, follow specific directions. Treat when air temperatures are between 60° 

### F and 90° 

### F. However, application may be made at 50° 

### F under rising temperature conditions. If daytime temperatures are warm, color response from ETHREL® treatment will be reduced, but ripening and loosening effects will be 

### accelerated. Cool weather may extend the intelVal between treatmentand harvest. Do not allow fruit to become overripe on trees. Fruit intended for fresh market must be checked for quality and maturity. Color alone is not an adequate guide for fruit maturity. Use a pressure gauge or other suitable methods for determining internal maturity. Fruit. over-matured when halVested and stored may soften sooner than untreated fruit.
Do not apply ETHREL ®to more acreage than can be halVested in 1

### to 2 

### days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of preharvest drop vary according to location and variety, follow directions on the FRUITONE® N label. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

Page 6 of20

## ETHREL® Crop Situation Pints/Acre 

### THINNING AND RETURN BLOOM



### t. Most Varieties 

### 1.5

- 4



### 2. Difficultto Thin 

### 3-6 Varieties Such as Golden Delicious

INCREASED FLOWER BUD DEVELOPMENT 

### 1. NON-BEARING 

### 2-8 TREES



### 2. BEARING 

### t12

- 3 TREES


### Use Limitations 

# APPLES (continued)
Specific Directions Treat 

### to to 20 days afterfull bloom. Forgreaterthinning, this product can 

### be mixed with AMID-THIN®W, SEVIN® brand 4F Carbaryl Insecticide, SEVIN® brand 80 WSP Carbaryllnsectic1de, SEVIN® brand 80 S Carbaryllnseclicide or SEVIN® brand XLR Plus Carbaryl Insecticide for use on apples in accordance with the mostrestrictive oftheAMIDTHIN®W, SEVIN®and ETHREL ® label nmitations and precautions. No label dosage rates should be exceeded. ETHREL ® cannot be mixed with any productcontaining a label prohibition against such mixing. Consult local extension recommendations. Addition ofa non-ionic surfactant can enhance treatmenteffectiveness. Buffering spray solution to a pH of3 to 5 can improve performance where water is alkaline. Use a spray volume sufficientto covertrees thorouqhlv and uniformI Spray trees thoroughly and uniformly to the point of runoff. Use the higher rate on more vigorous trees.
Treat 2 to 4 weeks afterfull bloom.

To help minimize fruit thinning, delay application until 6 weeks after fun bloom and afterJune droD. 

### Remarks Regulating cropping from one season to another is a problem. Whenever a high percent of the spurs 

### and lateral buds bloom in a single season severe alternate bearing can develop the following year. 

### To overcome this problem use 

### ETHREL® 

### or a combination of ETHREL® plus AMID-THIN® W or ETHREL® plus one of the SEVIN® products listed under Specific Directions applied 7 to 21 days after full bloom. The program to use will depend on the amount ofthinning required and the biennial bearing history ofyour orchard. Expect Red Delicious to show a reduction of "type" and fruit size particularly on trees understress. Use ofhigher label rates may reduce fruit size.

To increase flower bud development on non-bearing trees apply a foliar spray of ETHREL®2 to 4 weeks afterbloom. Treatment can result in excessive fruit thinning and reduced fruit size and yield reduction the year of usage. ETHREL® should reduce vegetative growth and increase flowering the following spring. Trees should be large enough to support a crop of apples before treatment to initiate flower buds.

The use ofETHREL ® brand Ethephon Plant Regulatorcan result in overthinning and reduced fruit size. Avoid double coverage and use on lowvigortrees. Environmental factors can affect thinning and return bloom, it is advisable to obtain experience under your conditions by initially testing only a small percent ofyourtrees each yearwith anyone program. User mustconsider risk of excessive fruit thinning and fruit size reduction**wh~n U~g**  ETHREL <Ill brand Ethephon Plant Regulator on young treesjuststarting to bear.

.**~** I 

### V\ f Treat onlyvigorous trees since excessivegrowth reduction 

### will result®'weak trees. For best results a thorough uniform spray is needed. A wetting agentmay improve spray coverage. Do notgraze or feed covercrops grown in treated apple orchards. Do not harvest apples treated with ETHREL <Ill brand Ethephon Plant Regulatorsoonerthan 7 days after last application. Fruit size reduction may occurwhen used to obtain early maturity, especially iffruit is small attime oftreatment. ETHREL ® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruit ualit and size.

\ Follow use rates listed above for labeled uses. Do notexceed 8.0 pints ofthis product(2.0 Ib ethephon) peracre peryear. 

# 'C. 'I

## .,tvt~

Page 7 of20

# BLACKBERRIES
BLACKBERRIES IN OREGON AND WASHINGTON: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator will concentrate maturity and loosen fruit, improving harvesting efficiencywhile reducing cane injury from mechanical harvest.

ETHREL® 

### Crop Situation PintslAcre 

### Specific Directions Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity. Use ETHREL ® : 

### 1) early in the harvest season to 

## AND apply a foliar spray of ETHREL® 

### at least 3 reduce the number of pickings or 2) treat later in WASHINGTON 

### days prior to expected harvest when air the harvestseason for a once-over final picking. 

### (Cultivars temperatures are between 60°F and gO°F Chehalem and rain is not predictedwithin 24 hours. Thornless and 

### Use sufficient volume to insure thorough Evergreen) and uniform wettinn offoliane and fruit. 

### Use Limitations

Do notspray morethan can be harvested on thethird dayfollowing treatmentas considerable fruit may drop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants. Do not harvestblackberries treated with ETHRELIII brand Ethephon Plant Regulatorsooner than 3 days after lastapplication. Do not exceed 8 pints ofthis product (2 Ib ai ethephon) per acre per year.


# BLUEBERRIES BLUEBERRIES: A foliar spray of ETHREL® brand Ethephon Plant Regulator concentrates maturity of blueberries for easier and more efficient harvest. A foliar spray of ETHREL ® 

### brand Ethephon Plant Regulatorwill abort black barrenberry (Aronia me/anocarpa) flowers andlorfruit growing in Maine lowbush blueberry fields reducing the numberof undesirable barrenberrv fruit harvestedwith blueberries. 

# 4"'" c: [ 

### ;; / 

### ETHREL® 

# /0, Crop Situation PlntslAcre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foliar spray of

## ETHR~® brand To concentrate first harvest, apply ETHREL ® 

### OF MATURITY Ethephon Plant Regulator at a r te of4 to brand Ethephon Plant Regulator when 15 to 20% AND EARLIER 8 pints in 150 to 200 gallons!per acre. of the berries are blue. To concentrate final FRUITCOLORING Use the higher spray volume and rate on harvest, treat after the first or second picking. (Cultivars Bluecrop, large dense foliage bushes 

### oc when Harvest blueberries 

### at proper maturity when Weymouth, Jersey, temperatures are cool. Treat when air colored, generally 

### ooe to two weeks after Rancocas, Rubel, temperatures are 60 to 900 

### F. treatment. Observe fruit daily 

# ., the proper Bluetta, Erliblue, Thorough uniform spray coverage 

### of picking period for optimum intemal and external Wolcott, Croatan, foliage and fruit is essential for maximum quality is shorter with ETHREL® brand Ethephon Murphy, Angola, fruit maturation 

### eod coloration. To aid Plant Regulator treated fruit than with untreated Morrow, Garden uniform wetting of plants, use a wetting fruit. High temperatures (90 0 

### F) accelerate fruit Blue, Trifblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 

### tOO gallons or X-77 at 2.0 pints per ETHREL ® treatments may increase fruit with 100 gallons. /]...

### ~) stems, slightly decrease fruit size, soluble solids 

# /' :?;' and acidity. ETHREL ® 

### may not induce internal 

### 0\ rioenina as raoidlv as fruit color. BLACK 

### 4-8

# APPI~/~~>8 piots pec acce of Et"REL® Use the lower rates of ETHREL® brand Ethephon BARRENBERRY bran hephon Plant Regul tor in Plant Regulator when black barrenberries are CONTROL IN LOW approximately**~1**

### 00 to 200 gallons er acre between 90 to 100% petal fall and use the higher BUSH rayers and approximately 10 rates of ETHREL ®

### when black barrenberry fruit is BLUEBERRIES IN gallons peracre for aerial application. 118 to 3116 inch in diameter. This is generally 7 to MAINE Thorough uniform spray coverage 

### i, 10 days after blueberries are in the same stages essential. To aid in uniform wetting of of development. Harvest blueberry fruit when plants, use a wetting agent such as X-77 ripe, generally 6 to 8weeks after application. at 0.1%ofthe sorav'volume, 

### Use Limitations

Applicationsto cultivarsotherthan those listed above may cause excessive steminess and/or premature crops. Make no more than one application per season. Ifused for barrenberry control in Maine, do not make a second application for blueberry concentration ofmaturity orcololing. Do nottreat blueberry plants underdroughtstress orexcessively high temperatures as defoliation and reduced yield may result. Page 8 of20

# CANTALOUPES
CANTALOUPES IN CALIFORNIA, ARIZONA, AND TEXAS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes abscission (slipping) offruit allowing more efficient and economical harvesting.



### ETHREL® 

### Crop Situation Pints/Acre Specific Directions Remarks CALIFORNIA, 

### 3 Good 

### spray coverage 

## ;, The effect will be faster at higher temperatures. Proper timing of 

### ARIZONA, important 

### foc producing 

### ETHRELill 

### treatment is 

### critical, but may vary from season to 

## TEXAS unifonn abscission. Use 40 season. Fruit quality, in terms of soluble solids and flesh color, 

### oc more gallons/acre 

### IOc does not improve following treatment. Therefore, ETHREL® should ground 

### aod 10 

### oc more not be used until after fruit has developed marketable levels of gallons/acre 

### foc aerial soluble solids and flesh color. ETHREL ® 

### promotes abscission of application. (Aerial immature fruit as well as marketable fruit. Thus, using ETHREL® applications 

### ace only too soon will result in poorly colored fruit with substandard soluble permitted in Texas.) solids. 

### Be prepared 

### to harvest Observe treated fields frequently and pick fruitwhen marketquality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long will lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary following treatment. Plants with low vigorwill not respond properly. with temperature. 

### Be sure Do not plant another crop within 30 days aftertreatment. 

### to coordinate your 

# I**~~~e~ting S~~~~ule**  with

our ackerlshi er. 

### Use Limitations

ETHREL®brand Ethephon Plant Regulatorshould not be appliedwhen nighttemperatures are below60°F. Treat only those fruit that have a fairly uniform fruit set, have vines in good condition, and have fruit with marketable soluble solids and internal flesh color. Do not treatfieldswhere soluble solids are running less than 10%. Do not harvest cantaloupes treated with ETHREL® brand Ethephon Plant Regulator soonerthan 2 days after last application. Do not exceed 3 pints ofthis product (0.75 Ib ethephon) per acre peryear.

Page 9 of20

# CHERRIES Except California CHERRIES: A 

### foliar spray of ETHREL

### ® brand Elhephon Plant Regulator loosens fruit and promotes early uniform ripening, and reduces the shakerforce needed to mechanically harvest fruil. These effects are important for increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree injury. DO NOT USE ON CHERRIES IN CALIFORNIA A fall application of ETHREL® to sweet cherries in the Pacific Northwest area increasesdormant bud hardiness and delays bloom the following spring


### Crop Situation ETHREL® 

### Pints/Acre Specific Directions Remarks
TART Dilute Spray Apply 

# ., , dilute spray 

### with sufficient 

### waler for CHERRIES 

### 1 thorough, uniform 

### coverage. Th. optimum spray 

### volume will depend on tree size, planting density and enuinment used. Concen- Concentrate sprays, generally less than 100 

### gallons per trate Spray acre, require uniform coverage for optimum response.

2/3 to 1

SWEET Dilute Spray Apply 

# " a dilute spray with sufficient water 

### foc Expect 

# , longer treatment 

### 10 CHERRIES 3t04 thorough uniform coverage. Actual volume will depend harvest Interval with lower rates. (varieties such as on the type ofdelivery, sprayer used and size oftrees. Windsor, Use low rates on the light oryellow-colored varieties. Napoleon-Royal Anne, Emperor Francis) Concen- Concentrate sprays, generally less than 100 

### gallons per trate Spray acre, require uniform coverage for optimum response. 

### 2-3

INCREASED 

### 3 Treat in first twoweeksofSeptember. A fall application of ETHREL® 

### will DORMANT increase fruit bod 

### hardiness by 

### FRUIT BUD decreasing the chance for winter HARDINESS injury and delaying bloom by 3 to 5 AND DELAYED days which may help avoid frost SPRING BLOOM injury. Treatment of early flowering (Sweet Cherries varieties may delay bloom to better in the**pa~~fic** 

### coincide with pollination from other Northwest varieties. 

### Use Limitations Not for use on cherries in California. Apply ETHREL® brand Ethephon Plant Regulator in a minimum spray volume of50 gallons per acre. Do not treat too early as this can cause early fruit dropwith stems attached. Some gummosis ofcherrytrees is associated with treatment. High temperatures during and afterapplication may cause severegummosis. Do nottreat trees that had severe gummosis the previousyear as tree damage will result. Do not apply to trees that are of low vigor or have experienced severe stress (such as winter injury, drought, or disease), since gummosis will be excessive, particularlywhen high temperatures and/or drought followtreatment. Ifpossible, irrigate orchards to prevent drought stress resulting in gummosis. Do not harvest cherries treated with ETHREL®soonerthan 7 days after last application. At the time ofapplication, all fruit including those inside the tree canopy, should be in stage 3 as indicated by rapid size increase and the presence of ground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and 85"F. Do not treat when air temperatures exceed 8S"F. Uniform coverage is important, concentrated sprays associated with erratic application can result in gummosis and lip dieback. Some early leafyellowing and drop may be noted following application. Slight gummosis and individual fruit size reduction may result with fall application bud hardiness treatment. Follow use rates listed abovefor labeled uses. Do not exceed 4.0 pints ofthis product (1.0 

### Ib ethephon) per acre peryear.
Page 10 of20

# GRAPES (Only in California andArizona)
GRAPES (TABLE GRAPES IN CALIFORNIAAND ARIZONA): An application of ETHREL

### ® brand Ethephon Plant Regulator promotes early uniform color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga, Queen and Tokay allowing more efficient harvests ofquality fruit. GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL® brand Ethephon Plant Regulator will hasten maturity of Thompson 

### seedless grapes resulting in reduced acids,**incr~d ~ars**  

### and increased raisin quality. /**4.~~** 

### Crop Situation 

### TABLE GRAPES 

### (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)

Use Limitations Table Grapes 

### ETHREL® PintsfAcre

112

- 2



## 1-2
1-2 

# - I Specific Directions**~ ~~~**  

### For hi temperatures**condition~** (above 859 F) use lower rates of 

### 1f2 to 1

### P-inLPef-acJ:ejF~**-~tures condition~** **~bove** 65°F)**use~€r**rates. Apply in sufficientwaterto wet vines and fruit clusters uniformly, using conventional ground sprayers. Treatwhen 5 - 30% of berries showcolor. Treat Tokays when 5 - 15"/" of berries showcolor. Apply as afoliar spray at 5% berry softening. Treat when 5 - 30% of berries showcolor. 

# '\ Remarks

## H~rvest fruit at desired maturity and quality as indicated by [;>ugar content, acidity and color. This is generally wo weeks or more aftertreatment. Watch treated areas closely and harvest before berries become too dark. For more information regarding local experiences with this producton grapes, consult your Farm Advisor 0' Extension Viticulturist.



### A foliar spray 

### of ETHREL® will hasten maturity 

### of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more information regarding local experience with this product on !orapes consultvour Farm Advisor or Extension Viticulturist.

Rates higher than 1 pintlA may increase the incidence ofcracked fruit and should be used only in areas orduring weather conditions where grapes have been especially hard-to-color in past seasons. Some berry softening is associated with ETHREL® brand Ethephon Plant Regulator treatment of some varieties which may limit or influence storage considerations. Do notstore Tokays. Do not harvestgrapes treatedwith ETHREL ® brand Ethephon Plant Regulatorsoonerthan 14 days after last application. Do not exceed 2 pints of this product (0.5 Ib ethephon) per acre peryear. Raisin Production (Thompson Seedless) Do not apply to grapes under stressfrom insect damage ormoisture stress. Observe treated vineyards closely and harvest at proper maturity as determined by sugar acid levels. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) per acre per year.

Page tt of20

# PEPPERS
PEPPERS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, uniform ripening and coloring for more efficient packing and handling offruit.



### ETHREL® 

### Crop Situation Pints/Acre Specific Directions Remarks 

### PEPPERS 1 1/4

- 4 

### Thorough coverage is essential. For ground or air Check several field locations to determine application choose equipment and spray volumes crop stage 

### aod degree of maturity. that will insure uniform coverage of foliage and 

### fruil. ETHREL® treatments 

### may 

### reduce total 

### Use the higher rate when cool temperatures are yields if 

### applied too early or there is a lack anticipated (less than 65"F), when plants 

### ace of uniform, mature, 

### green fruit resulting growing vigorously or when foliage is dense to 

### from split fruit set or variable soil cultural assure thorough wetting ofall leaves and fruit. practices. Harvest fruit after desired color Use the lower rates with lower spray volumes (1 t/4 

### and**maturity~**

### generally 14 or more days

# ~ ,.to 2 pint rate in 20 gallA) and higher rates with aftertreatmen " '**high~meS** 

### (3-4 pints/40 gallA). The 3-4 pint 

# cvv-t7_ 

# f"'c!ctc

....

L.V!?tl rate 'n ess than 40 gpa may cause foliage burn 

# .-:;\ underho '.

### ~~

-**~y** 

### Apply ETHREL® 

### to bell peppers when 10% of fruit are red and chocolate and to chili and pimento pepper varieties when 10to 30% of fruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL® will not ripen

### immature:Q~een fruit. 

### Use Limitations

Do notapplywhen prolonged average high temperatures of95"F aftertreatmentare expected. Do nottreat when temperatures exceed 100°F. Applications made under high temperatures will accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60°F. Low temperatures after treatment may reduce or negate the effects of ETHREL®brand Ethephon Plant Regulator. Some yellowing and general aging ofleaves will be noted aftertreatment. Do not harvest peppers treated with ETHREL® brand Ethephon Plant Regulator soonerthan 5daysafter last application. Do notexceed 4 pints ofthis product (1.0 Ib ai ethephon) peracre peryear. NOTE: Under certain conditions tank mixtures of ETHREL® 

### brand Ethephon Plant Regulator with desiccants containing sodium chlorate could result in the formation ofhypochlorous acids which on heating will emittoxic chloride fumes.

Page 12 of20

# PINEAPPLEAND SUGARCANE

CROP AND RATE PER SPRAY USE ACRE VOLUME APPLICATION TIMING 

### SPECIFIC COMMENTS RESTRICTIONS PINEAPPLE 

### Flower Induction 

# 1to:f 100

### to 500 'Bearing age' about 12 Proper rate will vary with 

# Do 001 graze 

### pineapple ETHREL® applied to 

### gallA months after planting. local growing conditions, forage treated 

### with pineapple plants will

.,-$ 

# It"'let.

# ?1 /" Generally about 6 months 

### varieties, plantation ETHREL® Do not halVes!**,~s** {Vl 

### stimulate uniform II 

## 1--:257 priorto desired harvest. 

### management practices pineapples 

### treated 

### with initiation offlowering. 

## he.5(G and time ofyear. 

### Use the ETHREL® 

### sooner than 2 

# \pJ,\
higher rate where earlier days after 

### Ihe 

### last harvest is desired. Apply application. 

### when pineapple foliage is 

### d",. Maturity

# ~ 100

### to 300 When the first fruit begin 

### Use 

### a broadcast spray, Concentration lntsY galfA to change color. thoroughly cover both 

# 'I ETHREL ® application foliage and fruit. Use the will stimulate uniform higher rate during periods shell color of cool or cloudy weather development when normal ripening has slowed. 

# ,**~-r:** SUGARCANE CL

### ~ r-c::..-\"-,:::..u '} Flower Prevention 1/2 pint 7 gallA Just prior 10 flower Apply by fixed wing

-or Do not halVest sugarcane ETHREL® application minimum initiation. hellcopter using equip- treated with ETHREL® will prevent or reduce ment designed 10 give sooner than 

### 2 months flowering and pithy uniform coverage. after the last application. tissue formation_ Actual biomass increase Do not graze sugarcane will be affected by the time forage treated with Biomass Increase 

## I between treatment 

### aod ETHREL®. ETHREL® used to halVest. preventflowering can 

### , also result in Consider anticipated 

### ceincreased biomass coverable sugars as well accumulation and as biomass to determine recoverable sugar optimum halVestdate. For Use In Hawaii Only. yield.



### , 

# Tl"est'.

## C~I' 1

.

# ~t~~\~~V\:f -Tt'vOS

# e, 0 

## V, 

# --J----L,e A6L{- 

# 2:'>7 1 

# <","be),

Page 13 of20

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE-CURED): A foliar sprayof ETHREL® brand Ethephon Plant Regulator promotes early, unffonn "yellowing" of mature 

### tobacco. ETHREL

### ® reduces curing time, allowing more efficient use of curing barn space, and increased control over harvest schedules. 

### ETHREL® brand Ethephon Plant Regulator increases the capacity of the curing barn by shortening the curing Ume and allows adjustments in harvestschedules. ETHREL

### ®can be used as a directed spray to the bottom or middle portion of the tobacco plant oras an over-the-top spray. ETHREL 

### ® is not intended or recommended for use on immaturetobacco.



### ETHREL® Crop Situation PintsfAcre Specific Directions 

### DIRECTED 4 Use drop nozzles. Choose TG or 

### DC spray tips designed to apply 50

- 60 gpa at35-40 psi and at SPRAY tractor speed of 2-3 mph. Use 2 nozzles per row; one on each slde of the row dropped low APPLICATION enough to direct the spray to the leaves to be ripened and harvested. Thorough spray coverage is essential. With a directed spray, be sure to harvest all leaves with 20% or more ellowinq. OVER-THE-TOP 

### 4-8 Treat only when leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a tendency to be more rank or when temperatures are lower than normal. Always test spray to detennine**if,.th~** tobacco is mature enough to respond to treatmentwith ETHREL®. \)

# dote. Apply over-the-top ETHREL® spray as a fine mist using three nozzles (one

# nozzl~ti6ver the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similar to the aoolication oattern ofsvstemicsucker control aaents. Use a sorav oressure of40 to 60 osi.


### USE LIMITATIONS Do not apply ETHREL® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality.
Do not aJlow the crop to over ripen in the field after using ETHREL® brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do nottreat before antiCipated majorstorm which could prevent harvest and result in crop loss. Do not apply ETHREL®brand Ethephon Plant Regulator ifrain is expected within 6 hours.
Do not harvest tobacco treated with ETHREL®brand Ethephon PlantRegulatorsoonerthan 2 days afterapplication. Follow use rates listed above for labeled uses. Do not exceed 8 pints ofthis product (2 Ib ethephon) per acre per year. 

### APPLICATION TIMING Successful results with ETHREL® brand Ethephon Plant Regulator call for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the proper treatment timing and the number of leaves perstalk ready for harvest. testspray several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves that fail to yellow in 72 hours are not mature and are not ready for ETHREL ® treatment. Wait a few days to pennit further natural maturing, then make anothertestspray or "maturity" check. Determine acres to treat byfirst confirming the numberof leaves per plantthatwill color, then use bam capacity to calculate the number ofacres to treat. A test spray can be prepared by mixing 4 teaspoons of ETHREL ® brand Ethephon Plant Regulator in 1 quart of water. Apply about 1 ounce to each test plant cove;g all leaveswith a fine mist. ETHREl ®will notcolor immature leaves. To avoid quality loss andtr";;"ossible leaf drop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. Limit use of higher rates to cool (below65°F atthe timeoftreatment) slow ripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREl ® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leaves have reached the desired color intenSity.

Page 14of20

### Harvest can commence 48 hours after ETHREL® brand Ethephon Plant Regulator application. To determine harvest timing and avoid quality loss or leafdrop, closely monltertreated crop and weatherconditions. 

### CURING ETHREL® BRAND ETHEPHON PLANT REGULATORTREATED TOBACCO Curing procedures are as much an art as a science and each cure must be judged on the basis oftobacco condition, interval between treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" and early "drying" stages ofthe leaf. Ethephon treated tobacco will have started the coloring process when harvested, reducing the time required in the coloring phase of curing. Treated tobacco should be dried faster. lftobacco leaves are green orcontain some green when harvested, it may 

### be necessary to color them for afew hours. Ifthe leaves are completely yellow, temperature and ventilation must be adjusted in a manne/to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you should follow normal procedures for cu ing. Since ETHREL®

### treated leaves cure faster, treated and untreated leaves should not

### be cured together in the same barn. 

## ...J:::""-r::-" ' '-.<;;

### ~ \ j ! C.-I 

# E::...-0J\ TOMATOES
TOMATOES (PROCESSED): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates and concentrates tomato ripening increasing recoverable fruit yield from a once-over harvest. Plant Regulator application starts the normal ripening process earlier and increases the rate of ripening of mature green fruit concentrating maturity. Concentrated maturity enables high recoverable yields of ripe tomatoes in once-over harvest. Early concentrated maturity extends the normal harvest season and helps growers schedule harvest and handling more effectively. TOMATOES (FRESH MARKET IN CALIFORNIA): A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator accelerates tomato ripening increasing the early yields ofmarketable ripe fruit.

Crop Situation PROCESS TOMATOES Early and Midseason Crops orWarm Conditions ETHREL® Pints{Acre 1114-31/4 

### Speciflc Directions Apply 1 

## y,. to 3 

### y:. pints per acre of ETHREL® brand Ethephon Plant Regulator in a minimum of20 gallons per acre for ground application and a minimum of 10 gallons per acre for aerial application. Apply when 5% to 15% 

### of the fruit in the field are red and pink (including breakers) and there is sufficient mature green fruit to produce the desired tonnage. Under high temperatures (above 85 F), rates as low as 1 1{4 pints/acre can be effective. Thorough coverage is essential. For ground or air application choose equipment and spray volumes that will assure uniform spray coverage of foliage and fruit. Overdosing from overlapping swaths or spray nozzle patterns can cause severe foliage injury. If bands are sprayed over the row, reduce the amount of ETHREL® used in proportion to the area actually treated. Observe treated fields closely and harvestfruit atproper maturity. Remarks Apply ETHREL® 

### when desired tonnage of fruit has reached marketable size and maturity. Check fields closely for stage and degree of uniform maturity prior to application. Sample several plants throughout the field to determine proper spray date. Sort, weigh and calculate the percent fruit which is red and pink, including breakers. Fruit size alone is not an adequate indicator. Observe specific directions to determine treabnent stage for your situation. Walk treated fields frequently to evaluate crop condition. Maintain normal cultural practice between treatment and harvest. Timely harvest is essential for maximum return of high quality fruit. Consult processor representatives concerning delivery schedules a!lct';\ 

### 00\-" c quotas priorto application of

## ~ 'f

# e.,t

# t**~** V

## ~\ \

.. Consult your local SayCCropScience"Representative, Extension Horticultural Specialist or Farm Advisor for suggestions on the proper use of ETHREL® when fields have variable plant vigor due to differences in soil conditions or cultural practices and for rates of fruit ripening as affected by temperature, within the rate and timing limitations shown on the label.

Page 15 of20

# TOMATOES (continued) 

### ETHREL® 

### Crop Situation PintsfAcre 

### Specific Directions Remarks 

## PROCESS 31/4-61/2 Apply 3 

### Y. to 6 14 

### pints per acre of ETHREL® brand Harvest at proper maturity. TOMATOES 

### Ethephon Plant Regulator in a minimum of 20 gallons per 

### Temperatures 

### above gO°F may Late Season or 

### acre for ground application and a minimum of 10 gallons cause fruit to ripen sooner whereas Coastal Crops or 

### per acre for aerial application. Apply when 5% to 30% of temperatures 

### below 65° F retard Cool Conditions 

### fruit in the field are red and pink (including breakers) and natural color development and may there is sufficient mature green fruit to produce the desired 

### extend the time between treatment 

### tonnage. Maximum response is achieved when fruit to be and harvest. treated is 5 to 15% pink and red. Use the higher rate of ETHREL® when nighttime temperatures are cool (below 65°F) or vegetative growth is dense. Thorough coverage is essential. For ground or air application choose equipment and sprayvolumes thatwill assure uniform spray coveraqe FRESH MARKET 1 1/4- 5 Apply ETHREL®when desired tonnage offruit has reached Check treated fruit frequently and TOMATOES marketable size and maturity, generally 3 to 6 days before harvest at desired maturity. Wheo California desired harvest date. Expect only one harvest from treated programming harvest, spray a areas. different block each day aod Apply t 

### Yo to 5 pints per acre of ETHREL® brand Ethephon harvest blocks daily in the same Plant Regulator in a minimum of 40 gallons per acre for sequence. ground application and a minimum of 10 gallons per acre for aerial application. Thorough coverage is essential. For ground or air application choose equipment and spray volumes thatwill assure uniform spraycoverage Use the higher rate and longer preharvest interval on late season crops, when temperatures are cool (generally below 85°F) and foliage is dense. Under high temperatures, rates as low as 1 t/4 pints per acre have been effective while reducing foliage damage particularly on more sensitive varieties

- see above. 

### Use Limitations Do not apply before there is sufficient mature green fruit to produce the desired tonnage. ETHREL ® brand Ethephon Plant Regulator will not ripen immature green fruit. Some yellowing and general aging offoliage may be observed following treatment. Do not treat plants with poor root systems or growing under stress due to poor soil conditions, drought, disease or insect damage. Treatment of weak plants will result in rapid loss offoliage cover increasing sunbum and sun scald potential, especially under high temperature conditions. Do nottreatwhen sustained temperatures above 105cF are antiCipated. Do not treat sensitive varieties during period when temperatures exceed 100°F. Foliar damage is more severe on certain varieties such as VF 10, VF 315, VF 145, 21-4, and t3L. During periods ofhigh temperatures use the lower rates on sensitivevarieties. Do nottank mix with sun protection products, sun protection whiteners, sprayadjuvants or other additives. Do notapply ETHREL ® brand Ethephon Plant Regulatorto more acreagethan can be harvested in 2 to 3 days. Do notapply ETHREL ® brand Ethephon Plant Regulatorto varieties known to soften rapidly orshatterwhen ripe. Do notuse on greenhouse tomatoes. Do not harvesttomatoes treated with Ethret® brand Ethephon Plant Regulatorsooner than 3 days afterlastapplication. Follow use rates listed above for labeled uses. Do not exceed 6.5 pints ofthis product (1.63Ib ethephon) peracre peryear.

Page 16of20

# WALNUTS
WALNUTS IN CALIFORNIA: A foliar sprayof ETHREL 

### ® brand Ethephon Plant Regulatorwill loosen walnuts for increased efficiency of mechanical harvest, promoteearlier harvest, improve hull removal, and increase recoverable yields from a once·overharvest. 

### Crop Situation


### California ETHREL® Pints/Acre 

### 3-5

USE LIMITATIONS Specific Directions Expect best results with spray concentrations of 

### 300 to 

### 900 ppm. 

### Refer to spray ETHREL® 

### preparation chart below. Under low temperatures and/or low humidity conditions use the higher label rates. Expect less time between application and harvest with higher 

### label rates. For best results treatwhen airtemperatures are 

### between 60°F and 95°F. Expect reduced effectiveness 

### if above gO°F with low humidity 

### dueto spray evaporation. Thorough uniform coverage of walnut hulls is essential for maximum hull split and nut loosening response. Choose equipment that provides maximum spray penetration of the entire tree canopy. Use large air carrier sprayers where tree sizejeopardizes coverage. Orvolute sprayer attachments may help.

Treatment priorto packing tissue brown (mature) stage may reduce nutquality. Some leafdrop is associated with treatment. Remarks Walnuts are mature when the packing tissue between kernel halves completes browning. Collect nut samples from throughout the tree canopywhen determining percent nut maturity. Advancing Harvest

- Apply when 95-100% of the nuts have reached maturity. Inspect frequently and harvest as soon as adequate hullability occurs generally 10-16 days after treatment depending on variety and weather conditions. Plan second shake 10-12 days afterfirst shake. Once Over Harvest

- Variety, growing conditions and weather affect maturity and the opportunity for once over harvest. Contact a local fieldman or Farm Advisor to determine jf once over harvest can be expected in your situation. Apply to mature walnuts 10 days prior to expected harvest date. Expect actual harvest to range from 7-12 days after treatment.

Do nottreat diseased, lowvigoror moisture stressed trees as excessive lea/drop may occur. Assure that dosage rates are measured accurately since rates higher than recommended may result in tree injury (such as excessive defoliation, reduced catkin formation and twig dieback). Do not harvestwalnuts treated with ETHREL ®soonerthan 5 days after last application. Do notexceed 5 pints ofthis product (1.25 Ib ethephon) per acre per year.

ETHREL@SPRAY PREPARATION CHART Sgray Volume (gallons/acre) ETHREL® Rate 

### 100 200 300 400 Pints/A Lbs/A Concentration (I2I2m) 

### 3 0.75 

### 900 450 300



## -- 4 1.00



## --- 600 400 300 5 1.25



## --- 750 500 375 500



## ---

--- 300

Page 170f20

# MISTLETOE REMOVAL
DWARF AND LEAFY MISTLETOE REMOVAL: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulator will remove dwarf mistletoe shoots in ornamental conifers and leafy mistletoe from ornamental deciduous trees.


## ETHREL® Crop Situation Amount 

### DWARF 2 pints 

### MISTLETOE ON pee 

## ORNAMENTAL 20 gallons CONIFERS DOUGLAS FIR 

### 1 pint ORNAMENTALS pee 

### 20 gallons

LEAFY 2 quarts MISTLETOE pee 

## ON 20 gallons ORNAMENTAL DECIDUOUS TREES Specific Directions 

### Remarks 

### Apply as a foliar spray to dwarf Applications made in conjunction with sylvicultural mistletoe shoots before 

### mistletoe mistletoe management 

### will prevent spread of the 

### seed dispersal. Foe effective 

### mistletoe parasite to other parts of the tree and 

### removal, all mistletoe shoots must other trees. 

### be sprayed to wet. Use of a non- Mature needle drop, that normally occurs in the 

### ionic surfactant at 

### recommended fall, may be hastened by the use of ETHREL$. 

### rates may increase effectiveness. Treat any mistletoe regrowth before Applications of higher rates on Douglas fir may seed dispersal. result in excessive needle drop. Make applications afterfall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. Foe 

### effective mesquite may be difficult 

### to control with a single removal. all mistletoe shoots must application and retreatment may be necessary. be sprayed to wet. Use of a nonionic surfactant at 

### recommended rates may increase effectiveness. Any mistletoe regrowth should be treated during the 

### labeled applicationwindow.


# FRUIT ELIMINATION (Ornamental UseOnly)
UNDESIRABLE FRUIT ELIMINATION: A foliar spray of ETHREL® brand Ethephon Plant Regulator will reduce or eliminate undesirable frujt developmenton apple. crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8 to 12ounces Apply as a foliar spray at the flower Application must be made before fruit set for best CRABAPPLES pee 

### bud to full bloom stage, priorto fruit results. set. Wet foliage thoroughly. Over Do not treat weak trees or trees under stress 20 gallons application of 

### ETHREL® Plant (drought. insect or disease damaged trees) as Do notexceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result. ounces (0.15 oz. leaf drop and/or tree 

### defoliation. Some leaf drop or temporary leaf yellowing may

ai/gallon) per 

### Use higher rates when application. temperatures are cool. occurafter treatment. CAROB 6 ounces Apply as a foliar spray. Wet all Do 

### not use 00 

### small red fruited varieties of (Cerafonia siliqua) pee 

### foliage thoroughly. Amount of spray crabapple 

# ., fruit elimination will oot be 

### 20Qallons will depend on tree size. satisfactory.
OLlVE* 12 ounces (Olea europaea) pee 

### 20 Qallons *This recommendation is not intended to be used on commelcial fruit production as a thinning agent.

Page t8 of 20

# TURF

An application ofEthrel slows the growth ofturfgrasses thus reducing the required frequency ofmowing and the volume ofclippings 

### collected.

SITES 

## RATE APPLICATION SPRAYVOLUME Fairways, Roughs & Commercial 

### 6 f) 

### 02/ 1,000 sq

### ft Applyto activelygrowing turf. Itwill 

### 0.5-4.0 9als/1,OOO sq ft Turfgrasses, including Bentgrass require 

### 7·10days for ETHREL®to (Fairway cut), Kentucky act. Reapplication intelVals: Bluegrass, Perennial Ryegrass, Kentucky Bluegrass-7wks. 

### Tall & 

### Fine Fescue Perennial Ryegrass-7 wks. Tall/Fine Fescue-4wks. Bentgrass-4 wks. 

### Use Limitations:

Do not allow entryto treated areas until sprays have dried. For best results, applywith sprayer in sufficientvolume ofwaterto provide uniform coverage. ETHREL® isfoliarly absorbed. Applyonly to actively growing turf, under1avorable growing conditions, that is notgoing intoa dormancy period. Do nottreatturfgrass with poor root systems orgrowing understress due to poor soil conditions, drought, disease or insectdamage. Do notapply to golfcourse greens. Use ofspreaders/stickers with ETHREl®is not necessary. ETHREl® is an acidicproduct and prolonged exposure to spraydepositswill damage acrylic plastiCS, certain paints and metals. Rinse thoroughly all exposed acrylic plasticmaterials and painted surfaceswith a detergent and waterwithin one hourafterexposure to spray deposits.
Testtankmixes with other products on a small area before using widely.

Page 19of20

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. Ifterms are notacceptable, return the unopened product containeratone. 

# ::r By

# Hsj~9...1~proi~'**i.!p~~el~cc{f;ts t~follo;ng**  t!bn s,'B£claimer

## ofWaITanties

# a~m1t<}t~ons of

# Liab1!~:Tro 

# "$t....oc.t1 co't:fcJmoNS?The

# direction~or

# ua**o~ b~duct**  e 

# b Ilev to be adequate and must be

# 1i5i1bw~unr"Howeve~ is impossible to eliminate aU risk associated with the e of

## thI" prod 

### ct. Crop injury, ineffectiveness or other unintended consequences may result because ofsuch 

### f ctors asweatherc 

### mons, pr senee f

### other materials, orthe manner of 

### LfS.e.-pl.§lPElicatio.F/, alLofwhich "; 

### are beyond the control ofBa er CropScience L

.

## An such ris s shall assumed by the user or

## b~yer.**C-~~ ~~** **'f~~, ~**  DISCLAIMER OF WARRANTIES: TO THE EXTENT CON ISTENT TH APPLICABLE LAW, AYER ROPSt)ENCE MAh'f NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHA TABILITY OR OF FITNE A PARTICULAR P SE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS DE ON THIS LABEL. No agent of Blr CropScience**LP.~** 

### authorized to make any warranties beyond those contained herein 0 to modify the warranties contained he ein. TO THE EXTE T ..,.....eoNSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATS EVER FOR SPECIA[, 

### (6**I~.f!.ll:** 

### TAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING**~"!!jI?** 

### ...PR D 

# Gft-o**tlAv~;-.s.cJ**

# t~'/\4fh IONS OF LIABILITY: T THE EXTENT CONSISTENT WITH APPLICABLE LAW, Tf:r1rmttfSIV (.(:EMEm OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT B7ER CROPSCIENCE**L~E~e:,r.~LACEMENT** 

### OF PRODUCT.



# NET CONTENTS:

# ~qe.:.e fMlV\-'\ 

# "AVENTI.,s-"**~** ':!

# e".I. f ""'"**~** 

# " +t,. Ii!.. 

## fill

# ~T is § "'"""'"" 

# '\ ETHREL is a registered trademark ofBayer.



### Pcod,ood foe

- 

# C**~**

# eJ.

# J

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# (:IOPSci('llce~r::

# ~~J y >

# ~, 'USA 

# LP 1/

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# 5

# e..t 'F'N' "'" "f\

# ve-.,. 

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# 11'ce\A.se.e:.e. ETHREL®brand Ethephon Plant Regulator (Pending)

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Page 20 of20

# ® 

# ETHREL brand 

# Ethephon Plant Regulator ForCommercial OrAgricultural Use Only. Not For Residential Use. 

## For use on Apples, Blackberries, Blueberries, Cantaloupes, Cherries, Grapes, Peppers, Pineapple, Sugarcane, Tobacco, Tomatoes, Walnuts, and for the removal of Dwarf Mistletoe in 

## Ornamental Conifers and Leafy Mistletoe in Ornamental Deciduous Trees and for the elimination of undesirablefruiton Apple, Crabapple, Carob, and Olivetrees. ACTIVE INGREDIENT: Ethephon [(2-chloroethyl)phosphonic acid]*

................. 

### ,,,.,,"",,

.....21.7% INERT INGREDIENTS:

.............. ............. ................ ............... 

### ...................78.3% *Contains 2 pounds ethephon pergallon. 

## EPA Reg. No. 264·267 EPA Est. No. 264·PA·01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entlende la etiqueta, busque a alguien para que S8 la explique a usted en detalie. (Ifyou do not understand the label, find someone to explain 

### itto you in detaiL) 

### For MEDICALAnd TRANSPORTATION Emergencies ONLY Call 24 HoursA Day**1..g00~334~7577** 

### For PRODUCT USE Information Call1-888-AVENTIS (1-888-283-6847) 

# FIRSTAID

IF IN EYES: 

## • Hold eye open and rinse slowlyand gentlywithwaterfor 15-20 minutes.


## • Remove contact lenses, 

### ifpresent, afterthefirst 5 minutes, then continue rinsing. 

# • Call a poison control center ordoctorfortreatment advice. 

### IF SWALLOWED: 

# • Immediatelycall a poison control centerordoctor for treatment advice. 

# • Do not induce vomiting unless told to do so 

### by a poison control centeror doctor. 

# • Have person sip a glass ofwater ifable to swallow. 

# • Do notgive anything by mouth to an unconscious person. IF ON SKIN OR 

## • Take offcontaminated clothing. CLOTHING: 

## • Rinse skin immediatelywith plentyofwaterfor 15-20 minutes.


## • Call a ooison control center ordoctorfortreatment advice. IF INHALED: 

## • Move person tofresh air. 

# • If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably mouth-tomouth if possible. 

# • Call a ooison control center ordoctorforfurthertreatment advice. For MEDICAL Emergencies Call 24 

### HoursA Day 1-800-334-7577. Have the product containeror label with you when calling a poison control center or doctororgoing fortreatment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use of gastric lavage. No specific antidote 

### is available. All treatments should be based on observed signs and symptoms of distress in the patient. Overexposure to materials other than this product may have occurred. Victims of severe overexposure by inhalation should be kept under medical observation for up to 72 hours for rlelaye-d onset of pulmonary edema. In a victim of overexposure by ingestion, careful gastric lavage is required due to-'he opssibilily ul !:;tomach or esophageal perforation. This material is an acid, butthe use ofalkaline substances to neutralize it is cont:·ainCicr.ted.

Page 1 of:O

# PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANSAND DOMESTIC ANIMALS Corrosive. Causes irreversible eye damage. Wear safetygoggleswhen handling. Harmful 

### if swallowed orabsorbed through skin. Do not get in eyes or on clothing. Avoid contactwith skin. Do not inhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials thatare chemical-resistant to this product are listed below. If you want more options, followthe instructions for Category A on an EPA chemical-resistance selection chart. 

### Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene orpolyvinyl chloride, shoesplus socks and protective eyewear. When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard for agricultural pesticides (WPS) [40 CFR 170.240 (d) (4-6)J, the handler PPE requirements may be reduced or modified as specified in the WPS. Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do not reuse them. Follow manufacturer'S instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hotwater. Keepand wash PPE separately from other laundry. 

## UserSafety Recommendations Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into clean clothing. The contaminated clothing should bewashed before reuse. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofglovesbefore removing. 

## ENVIRONMENTAL HAZARDS Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate waterwhen disposing ofequipmentwashwaters. 

# DIRECTIONS FOR USE It is a violation ofFederal Law to use this product in a manner inconsistentwith its labeling. Do not applythis product in a waythatwill contact workers or other persons, either directly orthrough drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulations. Read entire label before using this product. 

# AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers, and restricted-entry intervals. The requirements in this box only apply to uses ofthis product that are covered by the Worker Protection Standard. Do not enter or allowworkerentry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, chemical resistantfootwear plus socks, and goggles or face shield. Foroverhead exposure, chemical-resistant headgearis also required. Nol"Ifyworkers ofthe application bywarning them orallyand by posting warning signs at entrance totreated areas

.



### . .

Page

### '2 nf:'O

# STORAGE AND DISPOSAL PESTICIDE STORAGE Do notcontaminatewater, food, orfeed by storage and disposal. 

### PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal 

### law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe Hazardous Waste representative atthe nearest EPA Regional Office for guidance. Wastes resulting from the use ofthis product may be disposed ofon site orat an approved waste disposal facility. 

### CONTAINER DISPOSAL 

### Rigid, Non-refillable contaIners small enoughtoshake (i.e., with capacities equal to or less than 5 gallons) Non-refillable container. Do not reuse or refill this container. Offer for recycling, ifavailable. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipmentor a mix tank and drain for 10seconds after the flow begins todrip. Fill the container 

### t14 full withwaterand recap. Shake for 10seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 

### to seconds after the flow begins to drip. Repeat this procedure two more times. Then offerfor recycling orreconditioning or puncture and dispose of in a sanitary landfill.
ETHREL 

### ® BRAND ETHEPHON PLANT REGULATOR Promotes earlier, uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increases dormant fruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower induction, pineapple maturity concentration, sugarcane flower prevention and biomass increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe from ORNAMENTAL DECIDUOUS TREES. Eliminates undesirable fruit on APPLE, CRABAPPLE, CAROB, and OLIVE trees. 

### GENERAL INFORMATION For local recommendations on rates, spray volumes (gallons of water per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, Horticultural Specialist, Bayer CropScience Representative or Farm Advisor for his experience with this product in your area. 

### APPLICATION VOLUMES AND SPRAY COVERAGE Thorough spray coverage is essential to achieve maximum product effectiveness. Spray coverage is affected by choice of equipment, nozzle selection and spray boom setup as well as spray pressure, plantsize and canopydensity. For both air and ground applications, it is important to choose an equipment setup that will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will varywith the size and density ofthe plantcanopy and the equipment used. In California and AriZona use a volume of no less than 5 gallons peracre for aerial applications. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do not contaminate water used for irrigal"lon ordomestic purposes. Avoid spraydriftto nearby crops as this productwill cause modifications in plantgrowth. Plant injury or reduced yieldswill result. Do not plantanother cropwithin 30days aftertreatment. DO NOT MIX ETHREL® WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. Add 

### 'h to**~;.** of the required amount of water to the spray tank. Start agitation. Add the required amount of ETHREL ® brand Ethephon Plant Regulator. Mix onlythe amountofspray you expect to use each day. Do not allow mixed solution to stand overnight. Do not use ETHREL ® brand Ethephon Plant Regulatorwith additives otherthan recommended on this label. Avoid spills ofconcentrated product on spray equipment orairplane parts. IMMEDIATELY RINSE ANY SPILLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. tMPORTANT: Do not apply ETHREL® brand Ethephon Plant Regulatorthrough any type ofirrigation system. Do not use this productfor purposes otherthan those listed on the label. Do notexceed the rate of ETHREL ® brand Ethephon Plant Regulator peracre peryear recommended or this**la~el.**

Page :.< nf70

### SPRAY DRIFT Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift may result in illegal residues or injury to adjacent crops and vegetation, in the form of leafyellowing and defoliation. To avoid spray drift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFTAT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field crops. These requirements do not applyto forestry applications, public health uses orto applications using dry formulations. 1. The distance ofthe outer most nozzles on the boom must not exceed 3/4 

### the length ofthe wingspan or rotor. 2. Nozzles must always point backward parallel with the airstream and never be pointed downwards more than 45 degrees. Where states have more stringent regulatlons, they should be 

### observed. The applicatorshould be familiarwith and take into account the infonnation covered in the Aerial Drift Reduction Advisory below: 

### AERIAL DRIFT REDUCTION ADVISORY INFORMAnONON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and Temperature Inversions). CONTROLLING DROPLET SIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higherflow rate nozzles instead ofincreasing pressure. Numberof nozzles

- Use the minimum numberofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet size and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce largerdroplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 3/4 

### of the wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEIGHT Applications should not be made at a height greater than 10 feet above the top ofthe target plants unless a greater height is required for aircraft safety. Making applications at the lowest height that is safe reduces exposure ofdroplets to evaporation and wind. SWATH ADJUSTMENT When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance should increase, with increasing drift potential (higherwind, smaller drops, etc.). WIND Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should 

### be familiar with local wind patterns and how they affect spraydrift. TEMPERATURE 

### AND HUMIDITY When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet evaporation is most severewhen conditions are both hot and dry.

Page 4 (If70

### TEMPERATURE INVERSIONS Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the lightvariable winds common during inversions. Temperature inversions are characterized by increasing temperatures with altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. SENSITIVE 

### AREAS The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies ofwater, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray deposits will damage acrylic plastics, certain paints, and metals. Rinse thoroughly all exposed acrylic-plastic materials and painted surfaces with a detergent and waterwithin one hour after exposure to spray deposits.

Page 5 of20

# APPLES
APPLES: A foliar spray of 

### ETHREl ® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples, making harvest by 

### hand or machine easier and more efficient. ETHREL® applied in combination with FRUITONE@ N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruit Applied to young trees, ETHREL® will suppress vegetative growth and promote flower bud formation.



### Crop Situation FRUIT LOOSENING
1. 

### EARLYAND MIDSEASON MATURING VARIETIES (varieties maturing with Mcintosh or earlier) ETHREL® Pints/Acre

2 112 

### Specific Directions Apply afoliar spray to apple trees 7 to 14 days priorto normal anticipated harvest. Use sufficient water for thorough uniform spray coverage. The type ofsprayer used and size of trees will effect volume required. Observe fruit daily as the proper picking period is shorter with ETHREL® 

### treated fruit than untreated fruit. Do not exceed 

### 1.25 pounds ai/A per season. Remarks
ETHREL ® provides several beneficial responses 

### on apples. Depending on rate and time of application 

### ETHREl ®will: promote fruit loosening. 

### promote uniform ripening and coloring without loosening, promote thinning and return bloom, and increase flower bud development in 

### young trees. Fordesired response, follow specific directions. Treat when air temperatures are between 60° 

### F and 90° 

### F. However, application may be made at 50° 

### F under rising temperature conditions. If daytime temperatures are warm, color response from ETHREL® 

### treatment will be reduced, but ripening and loosening effects will be accelerated. Cool weather may extend the interval between treatment and harvest. 

### 2. LATE Do not allow fruit to become overripe on trees. MATURING Fruit intended for fresh market must be checked VARIETIES IN for quality and maturity. Color alone is not an THE EASTERN adequate guide for fruit maturity. Use a pressure UNITED STATES gauge or other suitable methods for determining (varieties internal maturity. Fruit over-matured v.nen maturing later harvested and stored may soften sooner than than Mcintosh) untreated fruit.

## ~~~~-----+----------~~ PROMOTION OF Apply foliar spray of ETHREL® 

### and a UNIFORM preharvest drop control chemical RIPENING AND registered for use on apples such as the COLORING OF RED product FRUITONE® N. Use the VARIETIES preharvest drop control product according WiTHOUT to label directions. Begin spraying 

### 2 to 

### 3 LOOSENING weeks before normal harvest period and about 

### 1 to 

### 2 weeks before desired harvestdate. 1. EARLYOR 1-4 MIDSEASON Apply as a normal dilute spray using MATURING sufficient water for thorough uniform VARIETIES coverage. Actual volume will depend on (varieties the type of delivery of**spra~r** 

### used and maturing with size oftrees. Mcintosh or Use the lower rate for apples intended for l--=eo'crlioecc):-.

___ 

# +

_____-1 storage. 

### 2. LATE MATURING VARIETIES (varieties maturing**late~,** 

### than MCintosh; 

### 2-4 Do not exceed 

### 1.25 pounds ai/A per season. Do not apply ETHREL® 

### to more acreage than can be harvested in 1

### to 2

### days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of preharvest drop vary according to location and variety, follow directions on the FRUITONE® N label. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

Page 6 of20ETHREL® 

### Crop Situation Pints/Acre THINNING AND RETURN BLOOM



### 1. MostVarieties 

### 1.5

- 4



### 2. Difficult to Thin 

### 3-6 Varieties Such as Golden Delicious

INCREASED FLOWER BUD DEVELOPMENT 

### 1. NON-BEARING 

### 2-8 TREES



### 2. BEARING 

### 1/2

- 3 TREES


### Use Limitations 

# APPLES (continued)
Specific Directions Treat 10 to 20 days after full bloom. Forgreaterthinning, this productcan be mixed with AMID-THIN®W, SEVIN® brand 4F Carbaryl Insecticide, SEVIN@brand 80WSP Carbaryl Insecticide, SEVJN® brand 80 S Carbaryllnseclicide orSEVIN® brand XLR Plus Carbaryl Insecticide for use on apples in accordancewith the most restrictive oftheAMIDTHIN®W, SEVIN® and ETHREL® label limitations and precautions. No label dosage rates should be exceeded. ETHREL ® cannot be mixed with any product containing a label prohibition againstsuch mixing. Consult local extension recommendations. Addition of a non-ionic surfactant can enhance treatment effectiveness. Buffering spraysolution to a pH of3 to 5 can improve performancewhere water is alkaline. Use a spray volume sufficientto covertrees thoroughly and uniformly. Spray trees thoroughly and uniformly to the point of runoff. Use the higher rate on more vigorous trees.
Treat2 to 4 weeks afterfull bloom.

To help minimize fruit thinning, delay application until 6 weeks after full bloom and afterJune drop. Remarks Regulating cropping from one season to another is a problem. Whenever a high percent of the spurs 

### and lateral buds bloom in a single season severe alternate bearing can develop the following year. 

### To overcome this problem use ETHREL® or a combination of ETHREL® plus AMID-THIN® W or ETHREL® plus one of the SEVIN® products listed under Specific Directions applied 7 to 21 days after full bloom. The program to use will depend on the amount ofthinning required and the biennial bearing historyofyour orchard. Expect Red Delicious to show a reduction of "type" and fruit size particularly on trees understress. Use of higher label rates may reduce fruit size.

To increase flower bud developmenton non-bearing trees apply a foliar spray of ETHREL® 2 to 4 weeks after bloom. Treatment can result in excessive fruit thinning and reduced fruit size and yield reduction the year of usage. ETHREL® should reduce vegetative growth and increase flowering the following spring. Trees should be large enough to support a crop of apples before treatmentto ·Initiate flower buds.

The use of ETHREL ®brand Ethephon Plant Regulator can result in overthinning and reduced fruit size. Avoid double coverage and use on low vigortrees. Environmental factors can affect thinning and return bloom, it is advisable 

### to obtain experience under your conditions by initially testing only a small percent ofyourtrees each yearwith anyone program. User must consider risk ofexcessive fruit thinning and fruit size reduction when using ETHREL ® brand Ethephon Plant Regulator on young treesjust starting to bear. Treatonlyvigorous trees since excessive growth reduction will result on weak trees. For best results a thorough uniform spray is needed. A wetting agent may improve spray coverage. Do not grazeor feed covercrops grown in treated apple orchards. Do not harvest apples treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 7 days after last application. Fruitsize reduction may occurwhen used to obtain early maturity, especially iffruit is small attime oftreatment. ETHREL® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruit guality and size. Follow use rates listed above for labeled uses. Do notexceed 8.0 pints ofthis product (2.0 Ib ethephon) peracre per year.

Page 7 of20

# BLACKBERRIES
BLACKBERRIES IN OREGON AND WASHINGTON: A foliar spray of ETHREL® 

### brand Ethephon Plant Regulator will concentrate maturity and loosen fruit, improving harvesting efficiencywhile reducing cane injury from mechanical harvest.



### ETHREL® 

### Crop Situation Pints/Acre Specific Directions Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity. Use ETHREL®: 1) 

### early in the harvest season to 

### AND apply a fonar spray of ETHREL® at least 3 reduce the number of pickings or 2) treat later in WASHINGTON days prior to expected harvest when air the harvestseason for a once-overfinal picking. 

### (Cultivars temperatures are between 60°F and gO°F Chehalem and rain is not predicted within 24 hours. 

### Thornless and Use sufficient volume to insure thorough Evergreen) and uniform wettinq offoliaae and fruit. 

### Use Limitations

Do not spray morethan can be harvested on the third day following treatment as considerable fruit may drop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants. Do not harvest blackberriestreatedwith ETHREL ® 

### brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Do not exceed 8 pints ofthis product (2 Ib ai ethephon) peracre peryear.


# BLUEBERRIES BLUEBERRIES: A foliar spray of ETHREL® 

### brand Ethephon Plant Regulator concentrates maturity of blueberries for easier and more efficient harvest. A foliar spray of ETHREL® brand Ethephon Plant Regulatorwill abort black barrenberry (Aronia mefanocarpa) 

### flowers andfor

### fruit growing in Maine lowbush blueberry fields reducing the numberof undesirable barrenberry fruit harvestedwith blueberries.
ETHREL® Crop Situation Pints/Acre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foliar spray of ETHREL ® 

### brand To concentrate first harvest. apply ETHREL® OF MATURITY Ethephon Plant Regulator at a rate of4 to brand Ethephon Plant Regulatorwhen 15 to 20% AND EARLIER 

### B pints in 150 to 200 gallons per acre. of the berries are blue. To concentrate final FRUIT COLORING Use the higher spray volume and rate on harvest, treat after the first or second picking. (Cultivars Bluecrop, large dense foliage bushes 

### oc when Harvest blueberries 

### a' proper maturity when Weymouth, Jersey, temperatures are cool. Treat when air colored, generally 

### ooe 

# '0 two weeks after Rancocas, Rubel, temperatures are 60 to 90° F. treatment. Observe fruit daily 

# " 'he proper Bluetta, Erliblue, Thorough uniform spray coverage 

### of picking period for optimum internal and external Wolcott, Croatan, foliage and fruit is essential for maximum quality is shorter with ETHREL ® 

### brand Ethephon Murphy, Angola, fruit maturation 

### aod coloration. To aid Plant Regulator treated fruit than with untreated Morrow, Garden uniform wetting of plants, use a wetting fruit. High temperatures (900 

### F) accelerate fruit Blue, Trifblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 100 gallons or X-77 at 2.0 pints per ETHREL® treatments may increase fruit with 100gallons. stems, slightly decrease fruit size, soluble solids and acidity. ETHREL® may not induce internal rioenina as raoidlv as fruit color. BLACK 

### 4-8 Apply 4 to 

### B pints per acre of ETHREL ® 

### Usethe lower rates of ETHREL ® 

### brand Ethephon BARRENBERRY brand Ethephon Plant Regulator 

### ;0 Plant Regulator when black barrenberries are CONTROL IN LOW approximately 100 to 200 gallons per acre between 90 to 100% petal fall and use the higher BUSH forground sprayers and approximately 10 rates of ETHREL ®

### when black barrenberry fruit is BLUEBERRIES IN gallons per acre for aerial application. 

### 1fBto 

### 3/16 inch in diameter. This is generally 7to MAINE Thorough uniform spray coverage 

### ;s 10 days after blueberries are in the same stages essenflal. To aid in uniform wetting of of development. Harvest blueberry fruit vtJen plants, use a wetting agent such as X-77 ripe, generally 6to 

### Bweeks afterapplication. at 0.1% ofthe sorav'volume. 

### Use Limitations

Applicationsto cultivars otherthan those listed above may cause excessive steminess andfor 

### premature crops. Make no morethan one application perseason. Ifusedfor barrenberry control in Maine, do not makea second application for blueberry concentrat'lon ofmaturityorcoloring. Do nottreat blueberry plants under drought stress or excessively hightemperatures as defoliation and reduced yield may result. Page 8 of20

# CANTALOUPES
CANTALOUPES IN CALIFORNIA, ARIZONA, AND TEXAS: A foliar spray of ETHREL ® brand Ethephon Plant Regulator promotes abscission (slipping) offruit allowing more efficient and economical harvesting.

ETHREL® 

### crop Situation 

### Pints/Acre Specific Directions Remarks 

### CAUFORNIA, 

### 3 Good spray coverage 

### ;s The effect will be faster at higher temperatures. Proper timing of 

### ARIZONA, important 

### foc producing 

### ETHREL® treatment is critical, but may vary from season to 

## TEXAS uniform abscission. Use 40 season. Fruit quality, in terms of soluble solids and flesh color, 

### oc more gallons/acre 

### foc does not improve following treatment Therefore, ETHREL ® should ground 

### aod 

### 10 oc more 

### not be used until after fruit has developed marketable levels of gallons/acre 

### foc aerial soluble solids and flesh color. ETHREL ® promotes abscission of application. (Aerial immature fruit as weJJ as marketable fruit. Thus, using ETHREL® applications 

### ace only too soon will result in poorly colored fruit with substandard soluble permitted in Texas.) solids. 

### Be prepared 

### to harvest Observetreated fields frequently and pick fruitwhen marketquality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long will lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary following treatment. Plantswith lowvigorwill not respond properly. with temperature. 

### Be sure Do not plantanothercropwithin 30 days aftertreatment. 

### to coordinate your harvest"lng schedule with 

# Iyour packer/shipper. 

### Use Limitations

ETHREL®brand Ethephon Plant Regulatorshould not be applied when nighttemperatures are below60QF. Treat only those fruit that have a fairly uniform fruit set, have vines in good condition, and have fruit with marketable soluble solids and internal flesh color. Do nottreatfieldswhere soluble solids are running less than 10%. Do not harvestcantaloupes treatedwith ETHREL® brand Ethephon Plant Regulatorsoonerthan 2 days after last application. Do not exceed 3 pints ofthis product (0.75 Ib ethephon) per acre peryear.

Page 9 of20

# CHERRIES Except California CHERRIES: A foliar spray of ETHREL® 

### brand Ethephon Plant Regulator loosens fruit and promotes early uniform ripening, and reduces the shakerforce needed to mechanically harvest fruit. These effects are important for increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree injury. DO NOT USE ON CHERRIES IN 

### CALIFORNIA. A fall application of ETHREL

### ® to sweet cherries in the Pacific Northwest area increasesdormant bud hardiness and delays bloom Ihe following spring.


### Crop Situation
TART CHERRIES 

## ETHREL® Pints/Acre Dilute Spray 

### 1

Concentrate Spray

2/3 to 

### 1 

### Specific Directions Apply as a dilute spray with sufficient water for thorough, uniform coverage. The optimum spray volume will depend on tree size, planting density and eouioment used. Concentrate sprays, generally less than 100 gallons per acre, require uniform coverage for optimum response. Remarks

SWEET CHERRIES (varieties such as Windsor, Napoleon-Royal Anne, Emperor Francis) Dilute Spray 

### 3 t04 Apply as a dilute spray with sufficient water for Expect a longer treatment to thorough unifonn coverage. Actual volume will depend harvest interval with lower rates.

INCREASED DORMANT FRUIT BUD HARDINESS AND DELAYED SPRING BLOOM (Sweet Cherries in the Pacific Northwest) 

### Use Limitations Concentrate Spray 

### 2-3

3

Notfor use on cherries in California. on the type of delivery, sprayer used and size of trees. Use low rates on the lightoryellow-colored varietJes.

Concentrate sprays, generally less than 100 gallons per acre, require uniform coverage for optimum response.

Treat in first two weeks ofSeptember. A fall application of ETHREL ® will increase fruit bud hardiness by decreasing the chance for winter injury and delaying bloom by 3 to 5 days which may help avoid frost injury. Treatment of early flowering varieties may delay bloom to better coincide with pollination from other varieties.

Apply ETHREL®brand Ethephon Plant Regulator in a minimum sprayvolume of50 gallons peracre. Do nottreattoo early as this can cause earlyfruit dropwith stems attached. Some gummosis ofcherry trees is associated with treatment High temperatures during and afterapplication may cause severegummosis. Do not treattrees that had severegummosis the previous year as tree damage will result. Do not apply to trees that are of low vigor or have experienced severe stress (such as winter injury, drought, or disease), since gummosis will be excessive, parflcularly when high temperatures and/or droughtfollow treatment. Ifpossible, irrigate orchardsto prevent drought stress resulting in gummosis. Do not harvestcherriestreated with ETHREL ® soonerthan 7 days after last application. Atthe time ofapplication, all fruit including those inside thetree canopy, should be in stage3 as indicated by rapid size increase and the presence of ground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and 85°F. Do not treat when air temperatures exceed 85"F. Uniform coverage is important, concentrated sprays associated with erralicapplication can result in gummosis and tip dieback. Some early leafyellowing and drop may be noted follOWing application. Slightgummosis and individual fruit size reduction may resultwith fall application bud hardiness treatment Forrow use rates listed above for labeled uses. Do not exceed 4.0 pints ofthis product(1.0 Ib ethephon) peracre peryear.
Page 10 of20

# GRAPES (Only in California andArizona)
GRAPES (TABLE GRAPES IN CALIFORNIAAND ARIZONA): An application of ETHREL® brand Ethephon Plant Regulator promotes early uniform color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga, Queen and Tokay aHowing more efficient harvests ofquality fruit. GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL® brand Ethephon Plant Regulator will hasten maturity of Thompson seedless grapes resulting in reduced acids, increased sugars and increased raisin quality.



### Crop Situation
TABLE GRAPES (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)


### Use Limitations Table Grapes 

## ETHREL® Pints/Acre



### 1/2

- 

### 2

1-2

1 - 2 Specific Directions For high temperatures conditions (above 85°F) use lower rates of 

### 1/2 to 1 pint peracre. For low temperalures conditions (but above 65°F) use higher rates. Apply in sufficientwatertowet vines and fruit clusters uniformly, using conventional ground sprayers. Treatwhen 5 - 30% of berries showcolor. Treat Tokays when 5 - 15% of berries showcolor. Apply as a foliar spray at 5% berry softening. Treat when 5 - 30% of berr"les show color. 

### Remarks Harvest fruit at desired maturity and quality as indicated by sugar content, acidity and color. This is generally two weeks or more aftertreatment. Watch treated areas closely and harvest before berries become too dark. For more information regarding local experiences with this product on grapes, consult your Farm Advisor 0' Extension Viticulturist.



### A foliar spray of ETHREL® will hasten maturity of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more information regarding local experience with this product on 

## Ioranes consultvour Farm Advisoror Extension Viticulturist.

Rates higherthan 1 pintiA may increase the incidence ofcracked fruit and should be used only in areas orduring weather conditions where grapes have been especially hard-to-color in past seasons. Some berry softening is associated with ETHREL ® brand Ethephon Plant Regulator treatment of some varieties which may limit or influence storage considerations. Do notstore Tokays. Do not harvest grapes treated with ETHREL ® brand Ethephon Plant Regulator soonerthan f4 days after last application. Do not exceed 2 pinls ofthis product (0.5 Ib ethephon) peracre peryear. Raisin Production (Thompson Seedless) Do not apply to grapes under stress from insect damage or moisture stress. Observe treated vineyards closely and harvestat proper maturityas determined by sugar acid levels. Do not exceed 2 pints ofthis product (0.5Ib ethephon) per acre per year.

Page 11 of20

# PEPPERS

PEPPERS: A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator promotes early, uniform ripening and coloring for more efficient packing and handling offruit.



### Crop Situation PEPPERS



### Use Limitations ETHREL® 

### Pints/Acre



### 1 1/4

- 4 Specific Directions Thorough coverage is essential. For ground or air application choose equipment and spray volumes that

### will insure uniform coverage of foliage and fruit 

### Use the higher rate when cool temperatures are anticipated (less than 65°F), when plants are growing vigorously or when foliage is dense to assure thorough wetting ofall leaves and fruit Use the lower rates with lower spray volumes (1 1/4 

### to 

### 2 pint rate in 

### 20 gallA) and higher rates with higher volumes (3-4 pintsJ40 gallA). The 3-4 pint rate in less than 40 gpa may cause foliage burn under hot dry conditions. Apply ETHREL I'll to bell peppers when 10% of fruit are red and chocolate and to chili and pimento peppervarieties when 10to 30% offruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL ® will not ripen immature, areen fruit. Remarks Check several field locations to determine crop stage and degree of maturity. ETHREL ® treatments may reduce total yields if applied too early or there is a lack of uniform, mature, green fruit resulting from split frult set or variable soil cultural practices. Harvest fruit after desired color and maturity, generally 14 or more days aftertreatment.

Do not applywhen prolonged average high temperatures of95°F aftertreatment are expected. Do nottreat when temperatures exceed 100°F. Applications made under high temperatures will accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60°F. Low temperatures after treatment may reduce or negate the effects of ETHREL® brand Ethephon Plant Regulator. Some yellowing and general aging ofleaves will be noted aftertreatment. Do not harvest pepperstreated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 5 days after last application. Do notexceed 4 pints ofthis product (1.0 Ib ai ethephon) peracre peryear. NOTE: Under certain conditions tank mixtures of ETHREL® brand Ethephon Plant Regulator with desiccants containing sodium chlorate could result in the formation ofhypochlorous acids which on heating will emittoxic chloride fumes.

Page 12 of20

# PINEAPPLEAND SUGARCANE

CROP AND RATE PER SPRAY 

### USE ACRE VOLUME 

### APPLICATION TIMING SPECIFICCOMMENTS 

### RESTRICTIONS PINEAPPLE 

### Flower Induction 1

### to 2

### pints 100 to 

### 500 'Bearing 

### age' about 

### t2 Proper rate will 

### vary with Do oot graze 

### pineapple ETHREL ® applied to 

### gallA months 

### after planting. local growing conditions, 

### forage treated 

### with pineapple plantswill Generally about 6 months varieties, 

### plantation ETHREL® Do not harvest stimulate uniform priortodesired harvest. management practices pineapples treated 

### with initiation offlowering. and time ofyear. Use the ETHREL ® sooner than 2 

### higher rate where earlier days after 

### the last harvest is desired. Apply application. when pineapple foliage is 

### dN. 

### Maturity 1/2

## to 2 100 to 

### 300 When the first fruit begin U,e a broadcast spray, Concentration pints gallA to change color. thoroughly cover both ETHREL ® application foliage and fruit. Use the will stimulate uniform higher rate durtng periods shell color of cool or cloudy weather development when normal ripening has slowed. SUGARCANE
Flower Prevention 

### 1/2 pint 7 gallA Just prior 

### to flower Apply 

### by fixed wing DC Do not harvest sugarcane ETHREL® application minimum initiation. helicopter uS'lOg equip- treated with ETHREL® will prevent or reduce ment designed 

### to give sooner than 

### 2 months flowering and pithy uniform coverage. after the last application. tissue formation. Actual biomass increase Do not graze sugarcane will be affected by thetime forage treated with Biomass tncrease between treatment 

### aod ETHREL®. ETHREL ® used to harvest. preventflowering can also result in Consider anticipated 

# ,.- increased biomass coverable sugars as well accumulation and as biomass to determine recoverablesugar optimum harvestdate. ForUse in Hawaii only. yield.

Page 13of20

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE.CURED): A foliar spray ofETHREL® brand Ethephon Plant Regulator promotes early. uniform "yellowing" ofmature 

### tobacco. ETHREL® reduces curing time, allowing more efficient use of curing barn space, and increased control over harvest schedules. 

### ETHREL® brand Ethephon Plant Regulator "Increases the capac"lty of the curing barn by shortening the curing time and allows adjustments in harvest schedules. ETHREL 

### ® can be used as a directed spray to the bottom ormiddle portion ofthe tobacco plant oras an over-the-top spray. ETHREL® is not intended or recommended for use on immature tobacco.


## ETHREL® Crop Situation Pints/Acre Specific Directions DIRECTED 

### 4 Use drop nozzles. Choose TG or OC spray tips designed 

### to apply 50

- 60 gpa at 35-40 psi and at SPRAY tractor speed of 2-3 mph, Use 2 nozzles per row; one on each side of the row dropped low APPLICATION enough to direct the spray to the leaves to be ripened and harvested. Thorough spray coverage is essential. With a directed spray, be sure to harvest all leaves with 20% or more 

### Iyellowing. OVER-THE-TOP 

### 4-8 Treat only when leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a terdency to 

### be more rank or when temperatures are lower than normal. Always test spray to determine if the tobacco is mature enough to respond to treatmentwith ETHREL ®. Apply over-the-top ETHREL® spray as a fine mist using three nozzles (one nozzle tips over the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similar to the application pattern ofsystemic sucker control aqents. Use a spray pressure of40 to 60 psi.


### USE LIMITATIONS Do not apply ETHREL® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality. Do not allowthe crop to over ripen in the field after using ETHREL ® brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do nottreat before anticipated major storm which could prevent harvest and result in crop loss. Do not apply ETHREL®brand Ethephon Plant Regulator ifrain is expected within 6 hours.
Do not harvesttobaccotreated with ETHREL® brand Ethephon Plant Regulator soonerthan 2 days after application. Follow use rates listed above for labeled uses. Do notexceed 8 pints ofthis product (2 Ib ethephon) per acre peryear. 

### APPLICATION TIMING Successful results with ETHREL® brand Ethephon Plant Regulator cal! for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready for harvest, test spray several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves that fail to yellow in 72 hours are not mature and are not ready for ETHREL ® treatment. Wait a fewdays to permit further natural maturing, then make anothertestspray or"maturity" check. Determine acres to treatby first confirming the number of leaves per plant thatwill color, then use barn capacity to calculate the number ofacres totreat. A test spray can be prepared by mixing 4 teaspoons of ETHREL® brand Ethephon Plant Regulator in 1 quart of water. Apply about 1 ounce to each test plant covering all leaves with a fine mist. ETHREL®will not color immature leaves. To avoid quality loss and or possible leafdrop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. Limit use of higher rates to cool (below 65°F atthe time oftreatment) slow ripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREL® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leaves have reached the desired color intensity.

Page 14 of20

### Harvest can commence 48 hours after ETHREL® 

### brand Ethephon Plant Regulator application. To determine harvest timing and avoid quality loss or leafdrop, closely monitortreated crop and weather conditions. 

### CURING ETHREL

### ® BRAND ETHEPHON PLANT REGULATOR TREATED TOBACCO Curing procedures are as much an art as a science and each cure must be judged on the basis oftobacco condition, interval between treatment and harvest, weather and type ofcuring facility before prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" and early "drying" stages ofthe leaf. Ethephon treated tobacco wi11 have started the coloring process when harvested, reducing the time required in the coloring phase of curing. Treated tobacco should be dried faster. Iftobacco leaves aregreen or contain some green when harvested, it may be necessary to color them for a few hours. Ifthe leaves are completely yellow, temperature and ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you should follow normal procedures for curing. Since ETHREL ® 

### treated leaves cure faster, treated and untreated leaves should notbe cured together in the same barn.


# TOMATOES
TOMATOES (PROCESSED): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates and concentrates tomato ripening increasing recoverable fruit yield from a once-over harvest. Plant Regulator application starts the normal ripening process earlier and increases the rate of ripening of mature green fruit concentrating maturity. Concentrated maturity enables high recoverable yields of ripe tomatoes in once-over harvest. Early concentrated maturity extends the normal harvest season and helps growers schedule harvest and handling moreeffectively. TOMATOES (FRESH MARKET IN CALIFORNIA): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates tomato ripening increasing the early yields ofmarketable ripe fruit.
ETHREL® CropSituation Pints/Acre Specific Directions Remarks PROCESS 1 

### 114 -31/4 Apply 1 

### y,; to 3 

### y,; pints per acre of Apply ETHREL® 

### when desired tonnage of fruit has TOMATOES ETHREL® brand Ethephon Plant reached marketable size 

### aod maturity. Check fields Early and Regulator in a minimum of20 gallons closely for stage and degree of uniform maturity prior to Midseason Crops per acre for ground application and a application. Sample several plants throughout the field to orWarm minimum of 10 ga110ns per acre for determine proper spray date. Sort, weigh and calculate Conditions aerial application. Apply when 5% to the percent fruit which is red and pink, including breakers. 15% of the fruit in the field are red Fruit size alone is not an adequate indicator. Observe 

### and pink (including breakers) 

### and speCific directions to determine treatment stage for your there is sufficient mature green fruit to situation. Walk treated fields frequently to evaluate crop produce the desired tonnage. condition. Maintain normal cultural practice betv-leen Under high temperatures (above 85 treatment and harvest. Timely harvest is essential for F), rates as low as 1 1/4 pints/acre maximum return of high quality fruit. Consult processor can be effectlve. representatives concerning delivery schedules 

### and Thorough coverage is essential. 

### Fo, quotas priorto application ofETHREL®. 

### ground or air application choose Consult your local Bayer CropScience Representative, equipment and spray volumes that Extension Horticultural Specialist or Farm Advisor for will assure uniform spray coverage of suggestions on the proper use of ETHREL® when fields foliage 

### and fruit. Overdosing from have variable plant vigor due to differences 

### in soil overlapping swaths or spray nozzle conditions or cultural practices and for rates of fruit patterns can cause severe foliage ripening as affected by temperature, 'Nithin the rate and injury. If bands are sprayed over the timing limitations shown on the label. row, reduce the amount of ETHREL® 

### used 

### in proportion 

### to the area actuallytreated. Observe treated fields closely harvestfruit at proper

### matu~itV. 

### and

Page t50f20

# TOMATOES (continued) 

## ETHREL® Crop Situation Pints/Acre 

### Specific Directions Remarks 

## PROCESS 31/4-61/2 Apply 3 

### Y. to 6 

### 'h pints per acre of ETHREL® brand Harvest ,( proper maturity. TOMATOES Ethephon Plant Regulator in a minimum of 20 gallons per Temperatures 

### above gO°F 

### m,y Late Season or acre for ground application and a minimum of 10 gallons cause fruit to ripen sooner whereas Coastal Crops or 

### per acre for aerial application. Apply when 5% to 30% of temperatures below 65" F retard Cool Conditions fruit in the field are red and pink (including breakers) and natural color development and may there is sufficient mature green fruit to produce the desired extend the time between treatment tonnage. Maximum response is achieved when fruit to be and harvest. treated is 5 to 15% pink and red. Use the higher rate of ETHREL® when nighttime temperatures are cool (below 65°F) or vegetative growth is dense. Thorough coverage is essential. For ground or air application choose equipment and SDrav volumes thatwill assure uniform SDrav coveraoe FRESH MARKET 1 

### 1/4

- 5 Apply ETHREL® when desired tonnage of fruit has reached Check treated fruit frequently and TOMATOES marketable size and maturity, generally 3 to 6 days before harvest at desired maturity. 

### Whee California desired harvest date. Expect only one harvest from treated programming harvest, spray 

# , areas. different block each 

### d,y oed Apply 1 

### y.. to 5 pints per acre of ETHREL® brand Ethephon harvest blocks daily in the same Plant Regulator in a minimum of 40 gallons per acre for sequence. ground application and a minimum of 10 gallons per acre for aerial application. Thorough coverage is essential. For ground or air application choose equipment and spray volumesthat will assure uniform spray coverage Use the higher rate and longer preharvest interval on late season crops, when temperatures are cool (generally below 85°F) and foliage is dense. Under high temperatures, rates as low as t 

### 1/4 pints per acre have been effective while reducing foliage damage particularly on more sensitfve varieties

- see above. 

### Use Limitations Do notapply before there is sufficient mature green fruit to produce the desired tonnage. ETHREL ® brand Ethephon Plant Regulator will not ripen immature green fruit. Some yellowing and general aging offoliage may be observed following treatment. Do not treat plants with poor root systems or growing under stress due to poor soil conditions, drought, disease or insect damage. Treatment ofweak plants will result in rapid loss of foliage cover increasing sunburn and sun scald potential, especially under high temperature conditions. Do nottreatwhen sustained temperatures above 105°F are anticipated. Do not treat sensitive varieties during period when temperatures exceed 10QoF. Foliar damage is more severe on certain varieties such as VF 10, VF 3t5, VF 145, 21-4, and t3l. During periods of high temperatures usethe lower rates on sensitive varieties. Do not tank mixwith sun protection products, sun protection whiteners, spray adjuvants orotheradditives. Do not apply ETHREL ® brand Ethephon Plant Regulatorto more acreage than can be harvested in 2 to 3 days. Do not apply ETHREL ® brand Ethephon Plant Regulator to varieties known to soften rapidly orshatterwhen ripe. Do not use on greenhousetomatoes. Do not harvest tomatoes treated with Ethrel® brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Follow use rates listed above for labeled uses. Do not exceed 6.5 pints ofthis product (1.63 Ib ethephon) per acre peryear.

Page t6 of20

# WALNUTS
WALNUTS 

### IN CALIFORNIA: A foliar spray of ETHREL® brand Ethephon Plant Regulatorwililooseo walnuts for increased efficiency of mechanical harvest, promote earlier harvest, improve hull removal, and increase recoverable yields from a once-over harvest. 

### Crop 

## ETHREL® Specific Directions Situation Pints/Acre Expect best results with spray concentrations of California 

### 3-5 300 to 

### 900 ppm. 

### Refer to spray ETHREL® preparation chart below. Under low temperatures and/or 

### low humidity conditions use the higher label rates. Expect less time between application and harvest with higher label rates. For best results treatwhen airtemperatures are between 60°F 

### aod 95°F. Expect reduced effectiveness if above 90°F with low humidity due to sprayevaporation. Thorough uniform coverage of walnut hulls is essential 

### for maximum hull split 

### aod ""I loosening response. Choose equipment that provides maximum spray penetration of the entire tree canopy. 

### Use large air carrier sprayers where tree sizejeopardizes coverage. Orvolute sprayer attachments may help.



### USE LIMITATIONS Treatmentpriorto packing tissue brown (mature) stage may reduce nutquality. Some leafdrop is associated with treatment. 

### Remarks Walnuts are mature when the packing tissue between kernel halves completes 

### brovvning. Collect nut samples from 

### throughout the tree canopywhen deteffilining percent nut maturity. Advancing Harvest· Apply when 95-100% of the nuts have reached maturity, Inspect frequently 

### "d harvest 

### as soon 

### as adequate hullability occurs generally 10-16 days after treatment depending on variety and weather conditions. Plan second shake 10-t2 daysafterfirst shake. Once Over Harvest

- Variety, growing conditions and weather affect maturity and the opportunity for once over harvest. Contact a local fieldman or Farm Advisor to determine if once over harvest 

### oao be expected 

### ;0 your situation. Apply 

### 10 mature walnuts 10 days prior to expected harvest date. Expect actual harvest to range from 7-12 days after treatment.

Do nottreatdiseased, lowvigoror moisture stressed trees as excessive leafdrop may occur. Assure that dosage rates are measured accurately since rates higher than recommended may result in tree iniury (such as excessive defoliation, reduced catkin fOllTlation and twig dieback). Do not harvest walnuts treated with ETHREL ® soonerthan 5 days after last application. Do notexceed 5 pints ofthis product (1.25 Ib ethephon) peracre peryear.

ETHREL

### ®SPRAY PREPARATION CHART**SQra~** Volume (gallons/acre) ETHREL® Rate 

### 100 200 300 400 PiotsfA LbsfA Concentration (ppm) 

### 3 0.75 

### 900 450 300



## -- 4 1.00


## --- 600 400 300 5 1.25


## --- 750 500 375 500



## ---

--- 300

Page 17 of20

# MISTLETOE REMOVAL
DWARF AND LEAFY MISTLETOE REMOVAL: A foliar spray of ETHREL® brand Ethephon Plant Regulator will remove dwarf mistletoe shoots in ornamental conifers and leafy mistletoe from ornamental deciduous trees.



### ETHREL® Crop Situation 

### Amount DWARF 

### 2 pints MISTLETOE ON 

### pee 

## ORNAMENTAL 20gallons CONIFERS DOUGLAS FIR 

### 1 pint ORNAMENTALS 

### pee 

### 20 gallons

LEAFY 2 quarts MISTLETOE pee 

## ON 20 gallons ORNAMENTAL DECIDUOUS TREES Specific Directions Remarks 

### Apply 

### as a foliar spray to dwarf Applications made in conjunction with sylvicultural mistletoe shoots before mistletoe mistletoe management will prevent spread of the 

### seed dispersal. 

### Foe effective 

### mistletoe parasite to other parts of the tree and removal, all mistletoe shoots must 

### othertrees. be sprayed to wet. Use of a non- Mature needle drop. that normally occurs in the ionic 

### surfactant at 

### recommended fall, may be hastened bythe use of ETHREL®. rates may increase effectiveness. Treat any mistletoe regrowth before Applications of higher rates on Douglas fir may seed dispersal. result in excessive needle drop. Make applications after fall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. Foe 

### effective mesquite may be difficult to control with a single removal, all mistletoe shoots must application and retreatment may 

### be necessary. be sprayed to wet. Use of a nonionic surfactant 

### at recommended rates may increase effectiveness. Any mistletoe regrowth should be treated during the 

### labeled application window.


# FRUIT ELIMINATION (Ornamental Use Only)
UNDESIRABLE FRUIT ELIMINATION: A foliar spray of ETHREL® brand Ethephon Plant Regulator will reduce or eliminate undesirable fruit development on apple, crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8 to 12 ounces Apply as a foliar spray at the flower Application must be made before fruit set for best CRABAPPLES pee 

### bud to full bloom stage, prior to fruit results. set. Wet foliage thoroughly. Over Do not treat weak trees or trees under stress 20 gallons application of 

### ETHREL® Plant (drought, insect or disease damaged trees) as Do notexceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result. ounces (0.15 oz. leaf drop and/or tree defoliation.

ai/gallon) per Use higher rates when Some leaf drop or temporary leaf yellowing may application. temperatures are cool. occur after treatment. CAROB 6 ounces Apply as a 

### foliar spray. Wet all Do not use on small red fruited varieties of (Ceratonia si/iqua) 

### pee 

### foliage thoroughly. Amount of spray crabapple 

# " fruit elimination will oot be 

### 20 gallons will depend on tree size. satisfactory.
OLlVE* 12 ounces (Olea europaea) 

### pee 

### 20 gallons 'This recommendation is not intended to be used on commercial fruit production as athinning agent.

Page 180f20

# TURF

An application of Ethrel slows the growth of !urfgrasses thus reducing the required frequencyofmowing and the volume ofclippings collected.

SITES 

### RATE APPLICATION SPRAYVOLUME Fairways, Roughs 

### & Commercial 6 

### fI 

### ozl 1,000

### sq ft Applyto activelygrowing turf. 

### Itwill 0.5-4.0gals/i,OOO sq 

### ft Turfgrasses, including Bentgrass require 7-10 days for ETHREL®to (Fairway cut), Kentucky act. Reapplication intervals: Bluegrass, Perennial Ryegrass, Kentucky Bluegrass-7 wks. Tall & Fine Fescue Perennial Ryegrass-7 wks. TaU/Fine Fescue-4 wks. Bentgrass-4 wks. 

### Use 

### Limitations:

Do not allow entryto treated areas until sprays have dried. Forbest results, applywith sprayer in sufficientvolume afwaterto provide uniform coverage. ETHREL® is foliarly absorbed. Apply only to activelygrowing turf, underfavorable growing conditions, that is notgOing into a dormancy period. Do nottreatturfgrass with poor rootsystems orgrowing under stress due to poorsoil conditions, drought, disease or insectdamage. Do not apply to golf course greens. Use ofspreaders/stickers with ETHREL®is not necessal)'. ETHREL® isan acidic product and prolonged exposureto spray deposits will damage aCl)'lic plastics, certain paints and metals. Rinse thoroughlyall exposed aCl)'lic plastic materials and painted surfaces with a detergent andwaterwithin one hourafterexposure to spray deposits.
Testtankmixes with other products on a small area before using widely.

Page 19 of20

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer ofWarranties and Limitations of Liability before using this product. Ifterms are not acceptable, return the unopened product container at once. By using this product, user orbuyeraccepts the following Conditions, Disclaimer ofWarranties and Limitations ofLiability. CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is impossible to eliminate all risks associated with the use ofthis product. Crop injury, ineffectiveness or other unintended consequences may result because ofsuch factors as weather conditions, presence ofother materials, or the manner ofuse or application, all ofwhich are beyond the control ofBayer CropScience LP. All such risks shall be assumed bythe userorbuyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE LP'S ELECTION, THE REPLACEMENT OF PRODUCT.



# NET CONTENTS:

ETHREL is a registered trademark of Bayer.

Produced for

Bayer CropScience P.O. Box 12014, 2 T.W. Alexander Drive Research Triangle Park, North Carolina 27709

ETHREL® brand Ethephon Plant Regulator (Pending) 01f20{10.

Page 20 of20

# ® 

# ETHREL brand 

# Ethephon Plant Regulator ForCommercial OrAgricultural Use Only. Not For Residential Use. For use on Apples, Blackberries, Blueberries, Cantaloupes, Cherries, Grapes, Peppers, 

## Pineapple, Sugarcane, Tobacco, Tomatoes, Walnuts, andforthe removal of DwarfMistletoe in Ornamental Conifers and Leafy Mistletoe in Ornamental Deciduous Trees and for the

I I I INERT INGREDIENTS:

...................................... 

### ......78.3% *Contains 2 pounds ethephon pergallon. 

## EPA Reg. No. 264-267 EPA Est. No. 264-PA-01 

# KEEP OUT OF REACH OF CHILDREN 

# DANGER PELIGRO

Si usted no entiende la etiqueta, busque a alguien para que S8 la explique a usted en detalle. (Ifyou do not understand Ihe label, find someone to explain it 10 you in detaiL) For MEDICALAnd TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577 For PRODUCT USE Information Call1-888-AVENTIS (1-888-283-6847) 

# FIRSTAID

IF IN EYES: 

## • Hold eye open and rinse slo'NIy and gentlywith waterfor 

### 15-20 minutes.


## • Remove contact lenses, ifpresent, afterthe first 

### 5 minutes, then continue rinsing. 

# • Call a poison control centerordoctorfor treatmentadvice. IF SWALLOWED: 

# • Immediately calla poison control centerordoctor for treatmentadvice. 

# • Do not induce vomiting unless told to do so bya poison control centerordoctor. 

# • Have person sip a glass ofwater ifable to swallow. 

# • Do notgive anything bv mouth to an unconscious person. IF ON SKIN OR 

## • Take offcontaminated clothing. CLOTHING: Rinse skin immediately 'lllith plenty ofwaterfor 

### 15-20 minutes. 

## • • Call a poison control center ordoctorfor treatment advice. IF INHALED: 

## • Move person to fresh air. 

# • If person is not breathing, call 

### 911 or an ambulance, then give artificial respiration, preferably mouth-tomouth ifpossible. 

# • Call a Doison control centerordoctorfor further treatmentadvice. For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7517. Have the productcontaineror label with you when calling a poison control center ordoctororqoinq for treatment. NOTE TO PHYSICIAN: Probable mucosal damage may contraindicate the use of gastric lavage. No specific antidote is available. All treatments should be based on observed signs and symptoms of distress in the patient. Overexposure to materials other than this product may have occurred. Victims of severe overexposure by inhalation should be kept under medical observation for up to 

### 72 hours for delayed onset of pulmonary edema. In a victim of overexposure by ingestion, careful gastric lavage is required due to the possibility of stomach or esophageal perforation. This material is an acid, but the use ofalkaline substances to neutralize it is contraindicated.

Paga 

### 1 .jf:O

# PRECAUTIONARY STATEMENTS DANGER HAZARDS TO HUMANS AND DOMESTIC ANIMALS Corrosive. Causes irreversible eye damage. Wear safety goggles VYhen handling. Harmful 

### ifswallowed or absorbed through skin. Do not 

### get in eyes oron clothing. Avoid contactwith skin, Do not inhale vapors as this productwill irritate mucous membranes. 

## PERSONAL PROTECTIVE EQUIPMENT (PPE) Some materials that are chemical-resistant to this product are listed below. Ifyou want more options, follow the instructions for Category A 

### on an EPA chemical-resistanceselection 

### chart Applicators and other handlers must wear long-sleeved shirts and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, shoes plus socks and protective eyewear. When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard for agricultural pesticides (WPS) 140 CFR 170.240 (d) (4-6»), the handler PPE requirements may be reduced or modified as specified in the WPS. Discard clothing and other absorbent materials that have been drenched or heavilycontaminated with this products concentrate. Do not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and hotwater. Keepand wash PPE separately from other laundry. 

## UserSafety Recommendations Users should wash hands befOre eating, drinking, chewing gum, using tobacco or using the toilet. Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and change into dean dothing. The contaminated clothing should be washed before reuse. Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing. Wash the outside ofgloves before removing. 

## ENVIRONMENTAL HAZARDS Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. Do not contaminate waterwhen disposing ofequipmentwashwaters. 

# DIRECTIONS FOR USE It is a violation of Federal Lawto usethis productin a manner inconsistentwith its labeling. Do not applythis product in a way thatwill contactworkers or other persons, eitherdirectly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulations. Read entire label before using this product. 

# AGRICULTURAL USE REQUIREMENTS
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers, and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard. Do notenteror allow workerentry into treated areas during the restricted-entry interval (REI) of48 hours. The REI is 72 hours in areas where average rainfall is less than 25 inches peryear. PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical-resistant gloves made of any waterproof material such as polyethylene or polyvinyl chloride, chemical resistant footwear plus socks, and goggles orface shield. For overhead exposure, chemical-resistant headgear is also required. Notify workers ofthe application bywarning them orally and by postingwarningsigns atentrance totreated areas.

Page 2 ,.,t::'O

# STORAGE AND DISPOSAL PESTICIDE STORAGE Do not contaminatewater, food, or feed by storage and disposal. 

### PESTICIDE DISPOSAL Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal Law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency orthe Hazardous Waste representative atthe nearest EPA Regional Office for guidance. Wastes resulting from the use ofthis product maybedisposed ofon site or at an approved waste disposal facility. 

### CONTAINER DISPOSAL 

### Rigid, Non-refillable containers small enoughto shake (Le., with capacities equal to or less than 5 gallons) Non-refillable container. Do not reuse or refill this container. Offer for recycling, if available. Triple rinse or pressure rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 

### 10 seconds afterthe flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 

### 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Drain for 

### 10 seconds after the flow begins to drip. Repeat this procedure two moretimes. Then offerfor recycling or reconditioning or puncture and dispose ofin a sanitary landfill. ETHREL 

### ® BRAND ETHEPHON PLANT REGULATOR Promotes earlier, uniform coloring of mature FLUE-CURED TOBACCO. Promotes earlier coloration and maturity of TOMATOES, GRAPES, APPLES, and PEPPERS. Loosens CHERRIES, WALNUTS, and APPLES for earlier, more efficient harvest. Promotes fruit abscission (slipping) in CANTALOUPES. Increases dormantfruit bud hardiness and delayed spring bloom ofSWEET CHERRIES in the Pacific Northwest. Accelerates BLACKBERRY ripening and loosening. Concentrates BLUEBERRY maturity and aids in barrenberry control, pineapple flower induction, pineapple maturity concentration, sugarcane flower prevention and biomass increase. Removes dwarf mistletoe from ORNAMENTAL CONIFERS and leafy mistletoe from ORNAMENTAL DECIDUOUS TREES. Eliminates undesirable fruit on APPLE, CRABAPPLE, CAROB, and OLIVE trees. 

### GENERAL INFORMATION For local recommendations on rales, spray volumes (gallons ofwater per acre), and spray equipment under varying temperature and rainfall conditions consult your Extension Pomologist, Horticultural Specialist, Bayer CropScience Representative or FallTl Advisor for his experience with this product in your area. 

### APPLICATION VOLUMES AND SPRAY COVERAGE Thorough spray coverage is essential to achieve maximum product effectiveness. Spray coverage is affected by choice ofeqUipment, nozzle selection and spray boom setup aswell as spray pressure, plant size and canopydensity. For both airand ground applications, it is important to choose an equipment setup that will assure thorough coverage of plant canopy (foliage and fruit). The actual spray volume required will varywith the size and density ofthe plant canopy and the equipment used. In California and Arizona use a volume ofno lessthan 

### 5 gallons peracre for aerial applications. 

### GENERAL PRECAUTIONS AND RESTRICTIONS Do notcontaminate water used for irrigation ordomesticpurposes. Avoid spraydriftto nearbycrops as this product will cause modifications in plantgrowth. Plant injury or reduced yields will result. Do notplant anothercropwithin 

### 30days aftertreatment. DO NOT MIX ETHREL® WITH AMMONIUM THIOSULFATE. SUCH TANK MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. Add 

### 'h to 

### Yo of the required amount ofwater to the spray tank. Start agitation. Add the required amount of ETHREL® brand Ethephon Plant Regulator. Mix onlythe amountofspray you expectto use eachday. Do not allow mixed solution to stand overnight. Do not use ETHREL ® brand Ethephon Plant Regulatorwith additives otherthan recommended on this label. Avoid spillS ofconcentrated producton sprayequipment or airplane parts. IMMEDIATELY RINSE ANY SPILLS WITH PLENTY OF WATER AS ETHREL® BRAND ETHEPHON PLANT REGULATOR IS CORROSIVE. IMPORTANT; Do notapply ETHREL® brand Ethephon Planl Regulatorthrough anytype ofirrigation system. Do not use this product for purposes otherthan those listed on the label. Do notexceed the rate ofETHREL ® brand Ethephon Plant Regulator per acre peryear recommended on this label.

Page 3::72')

### SPRAY DRIFT Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift may result in illegal residues or injury to adjacent crops and vegetation, in the fOml ofleafyellowing and defoliation. To avoid spraydrift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods oftemperature inversions. Use of larger droplet size will also reduce spray drift. AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipmenl-and-weather-related factors determine the potenlial for spray drift. The applicator is responsible for considering all these factors when making decisions. The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field crops. These requirements do not applyto forestry applications, public health uses orto applications using dryformulations. 1. The distance ofthe outermost nozzles on the boom must notexceed 3/4 the length ofthe wingspan or rotor. 2. Nozzles mustalways point backward parallel with the airstream and neverbe pointed downwards more than 45 degrees. Where states have more stringent regulations, they should be obselVed. The applicator should be familiarwith and take into accountthe information covered in the Aerial Drift ReductionAdvisory below: 

### AERIAL DRIFT REDUCTION ADVISORY INFORMATION ON DROPLET SIZE The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and Temperature Inversions). CONTROLLING DROPLET SIZE Volume

- Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger droplets. Pressure

- Do not exceed the nozzle manufacturer'S recommended pressures. For many nozzle types lower pressure produces larger droplets. When higherflow rates are needed, use higherflow rate nozzles instead ofincreasing pressure. Numberofnozzles

- Use the minimum number ofnozzles that provide uniform coverage. Nozzle Orientation

- Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other orientations and is the recommended practice. Significantdeflection from horizontalwill reduce dropletsize and increase drift potential. Nozzle Type

- Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce largerdroplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largestdroplets and the lowest drift. BOOM LENGTH For some use patterns, reducing the effective boom length to less than 3/4 of the wingspan or rotor length may further reduce drift without reducing swath width. APPLICATION HEIGHT Applications should not be made at a height greater than 10 feet above the top ofthe target plants unless a greater height is required for aircraft safety. Making applications atthe lowest heightthat is safe reduces exposure ofdroplets to evaporation and wind. SWATHADJUSTMENT When applications are madewith a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges ofthe field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance should increase, with increasing drift potential (higherwind, smallerdrops, etc.). WIND Drift potential is lowest between wind speeds of 2

- 10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and howtheyaffect spraydrift. TEMPERATURE AND HUMIDITY When making applications in low relative humidity, set up equipmentto produce largerdroplets to compensate for evaporation. Droplet evaporation is most severe when conditions are both hot and dry.

### TEMPERATURE INVERSIONS AppJlcations should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due to the Jightvariable winds common during inversions. Temperature inversions are characterized by increasing temperatureswith altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under lowwind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing. 

### SENSJTlVE AREAS The pesticide should only 

### be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies ofwater, known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive areas). 

### EQUIPMENT CLEANING Because of the acidic nature of this product, prolonged exposure to spray deposits will damage acrylic plastics, certain paints, and metals. Rinse thoroughly aJl exposed acrylic-plastic materials and painted surfaces with a detergent and waterwithin one hour after exposure to spraydeposits.

Page 5of20

# APPLES
APPLES: A foliar spray of ETHREL ® brand Ethephon Plant Regulator promotes fruit maturity and loosens apples, making harvest by 

### hand or machine easier and more efficient. ETHREL® applied in combination with FRUITONE® N to control pre-harvest drop stimulates early development of red color and ripening without loosening fruit. Applied to young trees, ETHREL

### ® 'Nill suppress vegetative growth and promote flower bud formation.



### Crop Situation FRUIT LOOSENING
1. EARLYAND MIDSEASON MATURING VARIETIES (varietfes maturingwith Mcintosh or earlier) ETHREL® Pints/Acre



### 2 1/2 Specific Directions Apply a foliar spray to apple trees 7 to 14 days priorto normal anticipated harvest. Use sufficient water for thorough uniform spray coverage. The type ofsprayer used and size of trees will effect volume required. Observe fruit daily as the proper picking period is shorter with ETHREL® 

### treated fruit than untreated fruit. Do not exceed 1.25 pounds ai/A per season. Remarks ETHREL® provides several beneficial responses 

### on apples. Depending on rate and time of application ETHREL ®will: promote fruit loosening, 

### promote uniform ripening and coloring without loosening, promote thinning and return bloom, and increase flower bud development in young trees. 

### Fordesired response, follow specificdirections. Treat when air temperatures are between 60° F and 90° F. However, application may be made at 50° F under rising temperature conditions. If daytime temperatures are wann, color response from ETHREL® 

### treatment will be reduced, but ripening and loosening effects will be accelerated. Cool weather may extend the interval between treatment and harvest. 2. LATE 5 Do not allow fruit to become overripe on trees. MATURING Fruit intended for fresh market must be checked VARIETIES IN for quality and maturity. Color alone is not an THE EASTERN adequate guide for fruit maturity. Use a pressure UNITED STATES gauge or other suitable methods for determining (varieties internal maturity. Fruit over-matured when maturing**late~,** 

### harvested and stored may soften sooner than than Mcintosh)

_ untreated fruit.

## ~~~~~---+------------~ PROMOTION OF Apply foliar spray of ETHREL® 

### and a UNIFORM preharvest drop control chemical RIPENING AND registered for use on apples such as the COLORING OF RED product**FRUITON~** 

### N. Use the VARIETIES preharvest drop control product according WiTHOUT to label directions, Begin spraying 2 to 3 LOOSENING weeks before normal harvest period and about 1 to 2 weeks before desired 1. 

### EARLY OR MIDSEASON MATURING VARIETIES (varieties maturing with 1

- 4 

### harvestdate. Apply as a normal dilute spray using sufficient water for thorough uniform coverage. Actual volume will depend on the type of delivery of sprayer used and size oftrees. Use the lower rate for apples intended for 

# 1--'==-'-----+-------1storage. 2 - 4 Do not exceed 1.25 pounds ailA 

### per Mcintosh or earlier) 

### 2. LATE MATURING season. VARIETIES (varietfes maturing later than Mcintosh) Do not apply ETHREL®

### to more acreage than can be harvested in 1to 2 days. Treated fruit can be satisfactorily held in cold air storage provided fruit is in good condition. Since recommendations for chemical control of preharvest drop vary according to location and variety, follow directions on the**FRUITON~** 

### N label. In addition, you may consult your local extension Pomologist or Horticulturist for his recommendations.

Page 6 of20

# APPLES (continued)
ETHREL® Crop SItuation 

### Pints/Acre Specific Directions 

### Remarks THINNING AND Treat 10 to20days afterfull bloom. 

### Regulating cropping from one season to another is RETURN BLOOM Forgreaterthinning. this product can 

### a problem, Whenever a high percent of the spurs be mixed with AMID-THIN®W, 

### and lateral buds bloom in a single season severe SEV1N® brand 4F Carbaryl alternate bearing can develop the following year. 

### 1.5

- 4 Insecticide, SEVIN® brand 80 WSP 

### To overcome this problem ooe ETHREL® 

### or a 1. MostVarieties Carbaryl Insecticide, SEVIN® brand combination of ETHREL® plus AM1D-TH1N® W or 80 S Carbaryl Insecticide or SEVIN® 

### ETHREL® plus one of the SEVlN® products listed brand XLR Plus Carbaryl Insecticide under Specific Directions applied 7 to 21 days after 

### 2. Difficultto Thin 

### 3-6 for use on apples in accordance with full bloom. The program to use will depend on the Varieties Such the most restrictive ofthe AMID· amountofthinning required and the biennial bearing

as Golden THIN®W, SEVIN®and ETHREL® history ofyour orchard. Delicious label limitations and precautions. No Expect Red Delicious to show a reduction of "type" label dosage rates should be and fruit size particularly on trees understress. exceeded. ETHREL®cannot be Use ofhigherlabel rates may reduce fruit size. mixed with any product containing a label prohibition againstsuch mixing. Consult local extension recommendations. Addition ofa non-ionic surfactant can enhance treatmenteffectiveness. Buffering spray solution to a pH of3 to 5 can improve perfoJ1T1ance where water is alkaline. Use a sprayvolume sufficient to covertrees thoroughly and unifoJ1T11 INCREASED Spray trees thoroughly and uniformly To increase flower bud development on non-bearing FLOWER BUD to the point of runoff. Use the higher trees apply a foliar spray of ETHREL ® 2 to 4 weeks DEVELOPMENT rate on more vigorous trees. after bloom. 

### 1. NON-BEARING 

### 2-8 Treatment can result in excessive fruit thinning and TREES Treat 2 to 4 weeks afterfull bloom. reduced fruit size and yield reduction the year of usage. ETHREL® should reduce vegetative growth 

### 2. BEARING**1/2~3** To help minimize fruit thinning, delay and increase flowering the following spring. Trees TREES application until 6 weeks after full should be large enough to support a crop of apples bloom and afterJune drop. before treatmentto initiate flower buds. 

### Use Limitations The use of ETHREL®brand Ethephon Plant Regulatorcan result in overthinning and reduced fruit size. Avoid double coverage and use on lowvigortrees. Environmental factors can affect thinning and return bloom, it is advisable to obtain experience under your conditions by initially testing only a small percentofyourtrees each yearwith anyone program. Usermustconsider risk ofexcessive fruitthinning and fruit size reduction when using ETHREL® brand Ethephon Plant Regulator on young treesjuststarting to bear. Treat onlyvigoroustrees since excessive growth reductionwill result on weak trees. For bestresults a thorough uniform spray is needed. A wetting agentmay improve spray coverage. Do not graze or feed covercrops grown in treated apple orchards. Do not harvest apples treated with ETHREL®brand Ethephon Plant Regulatorsoonerthan 7 days afterlast application. Fruitsize reduction mayoccurwhen used to obtain early maturity, especially iffruit is small attime oftreatment. ETHREL® brand Ethephon Plant Regulator applied earlier than 3 weeks before normal anticipated harvest may result in reduced fruit guality and size. Follow use rates listed above for labeled uses. Do not exceed 8.0 pints ofthis product (2.0 Ib ethephon) per acre peryear.

Page 7 of20

# BLACKBERRIES
BLACKBERRIES IN OREGON AND WASHINGTON: A foliar spray of ETHREL® brand Ethephon Plant Regulator will concentrate maturity and loosen fruit, improving harvesting efficiencywhile reducing cane injury from mechanical harvest.



### ETHREL® 

### Crop Situation 

### PintslAcre Specific Directions Remarks
IN OREGON 

### 5-8 To loosen fruit and concentrate maturity. 

### Use ETHREL®: 1) early in the harvest season to 

### AND apply a foliar spray of 

### ETHREl ® at least 3 reduce the number of pickings or 2) treat later in 

### WASHINGTON 

### days prior to expected harvest when air the harvestseason for a once-overfinal picking. (Cultivars temperatures are between 60°F and gO°F Chehalem and rain is not predicted within 24 hours. Thornless and Use sufficient volume to insure thorough Evergreen) and uniform wettino offoliaae and fruit. 

### Use Limitations

Do notspraymore than can be harvested on the third dayfollowing treatment as considerablefru·rt maydrop. Use only at recommended times and rates on healthy, vigorous plants, as a reduction in berry size may occur. Do not use on damaged ordiseased plants. Do notharvest blackberries treatedwith ETHREL ® brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Do not exceed 8 pints ofthis product (21b ai ethephon) peracre per year.


# BLUEBERRIES BLUEBERRIES: A foliar spray of ETHREL® brand Ethephon Plant Regulator concentrates maturity of blueberries for easier and more efficient harvest. A foliar spray of ETHREL ® brand Ethephon Plant Regulator will abort black barrenberry (Aronia me/anocarpa) flowers andlorfruit growing in Maine lowbush blueberryfields reducing the numberofundesirable barrenberry fruit harvested with blueberries.

ETHREL® Crop Situation PintslAcre Specific Directions Remarks CONCENTRATION 

### 4-8 Apply a foliar spray of ETHREL ® brand To concentrate first harvest, apply ETHREL® OF MATURITY Ethephon Plant Regulator at a rate of4 to brand Ethephon Plant Regulatorwhen 15to 20% AND EARLIER 8 pints in 150 to 200 gallons per acre. of the berries are blue. To concentrate final FRUIT COLORING Use the higher spray volume and rate on harvest, treat after the first or second picking. {Cultivars Bluecrop, large dense foliage bushes 

## oc when Harvest blueberries 

## ,t proper maturlty when Weymouth, Jersey, temperatures are cool. Treat when air colored, generally 

## one to two weeks after Rancocas, Rubel, temperatures are 60 to 900 F. treatment. Observe fruit daily as the proper Bluetta, Erliblue, Thorough uniform spray coverage 

## of picking period for optimum intemal and external Wolcott, Croatan, follage and fruit is essential for maximum quality is shorter with ETHREL® brand Ethephon Murphy, Angola, fruit maturation 

# ,,' coloration. 

## To aid Plant Regulator treated fruit than with untreated Morrow, Garden uniform wetting of plants, use a wetting fruit. High temperatures (900 F) accelerate fruit Blue, Trifblue and agent such as Triton B-1956 at 0.5 pint ripening. NC901) per 100 gallons or X-77 at 2.0 pints per ETHREL® treatments may increase fruit with 100 gallons. stems, slightly decrease fruit size, soluble solids and acidity. ETHREL lID may not induce internal ripening as rapidly as fruit color. BLACK 

### 4-8 Apply 4 to 8 pints per acre of ETHRELlID Use the lower rates of ETHREL ®brand Ethephon BARRENBERRY brand Ethephon Plant Regulator 

### in Plant Regulator when black barrenberries are CONTROL IN LOW approximately 100 to 200 gallons per acre between 90 to 100% petal fall and use the higher BUSH forground sprayers and approximately 10 rates of ETHREL lID when black barrenberry fruit is BLUEBERRIES IN gallons per acre for aerial application. 1/8 to 3/16 inch in diameter. This is generally 7 to MAINE Thorough uniform spray coverage 

### i, 10 days after blueberries are in the same stages essential. To aid in uniform wetting of of development. Harvest blueberry fruit when plants, use a wetting agent such as X-77 ripe, generally6 to 8weeks afterapplication. at0.1% ofthe spray volume. 

### Use Limitations

Applications to cultivars otherthan those listed above may cause excessive steminess 

### andlorpremature crops. Make no more than one application perseason. Ifused for barrenberry control in Maine, do notmake a second application for blueberry concentration ofmaturity orcoloring. Do nottreat blueberry plants underdrought stress orexcessively high temperatures as defoliation and reduced yield may result. Page 8 of20

# CANTALOUPES
CANTALOUPES IN CALIFORNIA, ARIZONA, AND TEXAS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes abscission (slipping) offruit allowing more efficient and economical harvesting.


### ETHREL® 

### Crop Situation Pints/Acre Specific Directions Remarks CALIFORNIA, 

### 3 Good 

### spray coverage " The effect will be faster at higher temperatures. Proper timing of 

### ARIZONA, important for 

### producing ETHREL® 

### treatment is critical, 

### but may vary from season to 

## TEXAS uniform abscission, Use 40 

### season. Fruit quality, in terms of soluble solids and flesh color, or more gallons/acre foe does not improve following treatment. Therefore, ETHREL ® should ground 

## "d 10 or more 

### not be used until after fruit has developed marketable levels of 

### gallons/acre for aerial soluble solids and flesh color. ETHREL® promotes abscission of application. (Aerial immature fruit as well as marketable fruit. Thus, using ETHREL ® applications are only too soon will result in poorly colored fruit 'Nith substandard soluble permitted in Texas.) solids. Be prepared to harvest Observe treated fields frequently and pick fruitwhen marketquality abscised fruit 2 to 5 days is reached. Fruit allowed to remain in the field too long 'Nill lose after treatment. The exact quality. Some yellowing or rapid aging of vines will be seen pre-harvest interval will vary follO'Ning treatment. Plants with low vigorwill not respond properly. with temperature. Be sure Do not plant anothercrop within 30 days aftertreatment. to coordinate your harvesting schedule with your packer/shioDer. 

### Use Limitations

ETHREL® brand Ethephon Plant Regulator should not be applied when nighttemperatures are below60"F. Treat only those fruit that have a fairly uniform fruit set, have vines in good condition, and have fruit with marketable soluble solids and internal flesh color. Do nottreat fieldswhere soluble solids are running less than 10%. Do not harvestcantaloupes treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 2 days after lastapplication. Do notexceed 3 pints ofthis product (O.75Ib ethephon) peracre peryear.

Page9 of20

# CHERRIES Except California CHERRIES: A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator loosens fruit and promotes early uniform ripening, and reduces the shaker force needed to mechanically harvestfruit. These effects are important for increasing efficiency, recoverable yields, 

### maintaining fruit quality and reducing tree injury. DO NOT USE ON CHERRIES IN CALIFORNIA. A fall application of ETHREL® to sweet cherries in the Pacific Northwestarea increases dormant bud hardiness and delays bloom thefollowing spring. 

## ETHREL® Crop Situation Pints/Acre Specific Directions 

### Remarks 

### TART Dilute Spray 

### Apply 

# " a dilute 

### spray with sufficient 

### water for CHERRIES 1 thorough, uniform 

### coverage. The optimum 

### spray volume will depend on tree size, planting density and equipment used. Concen- Concentrate sprays, generally less than tOO gallons per trate Spray acre, require uniform coverage for optimum response.

2/3 to 1

SWEET Dilute Spray Apply 

### a, a dilute spray with sufficient water 

### foc Expect 

### a longer treatment 

### to CHERRIES 3 to4 thorough uniform coverage. Actual volume will depend harvest interval with lower rates. (varieties such as on the type of delivery, sprayer used and size of trees. Windsor, Use low rates on the light oryellow-colored varieties. Napoleon-Royal Anne, Emperor Francis) Concen- Concentrate sprays, generally less than 100gallons per trateSpray acre, require uniform coverage for optimum response. 

### 2-3

INCREASED 

### 3 Treat in first two weeks 01 September. A fall application of ETHREL ® will DORMANT increase fruit bud hardiness 

### by FRUIT BUD decreasing the chance for winter HARDINESS injury and delaying bloom by 3 to 5 AND DELAYED days which may help avoid frost SPRING BLOOM injury. Treatment ofearly flowering (Sweet Cherries varieties may delay bloom to better in the Pacific coincide with pollination from other Northwest) varieties. 

### Use Limitations Notfor use on cherries in Calilornia. Apply ETHREL®brand Ethephon Plant Regulator in a minimum spray volume of50gallons per acre. Do not treattooearly as this can cause early fruit dropwith stems attached. Some gummosis ofcherrytrees is associated with treatment. High temperatures during and afterapplication may causesevere gummosis. Do not treat trees that had severegummosis the previous yearas tree damagewill result. Do not apply to trees that are of low vigor or have experienced severe stress (such as winter injury, drought, or disease), since gummosiswill be excessive, particularly when high temperatures and/ordrought followtreatment. Ifpossible, irrigate orchards to preventdroughtstress resulting in gummosis. Do not harvest cherries treated with ETHREL ® soonerthan 7 days after lastapplication. At the time 01 application, all fruit including those inside the tree canopy, should be in stage 3 as indicated by rapid size increase and the presence ofground color (change from bright green to yellow background color). Treat when air temperatures are between 60 and 85°F. Do not treat when air temperatures exceed 85°F. Uniform coverage is important, concentrated sprays associated with erraticapplication can result in gummosis and tip dieback. Some early leafyellowing and drop may be noted following application. Slight gummosis and individual fruit size reduction may resultwith fall application bud hardiness treatment. Follow use rates listed above for labeled uses. Do not exceed 4.0 pints ofthis product (1.0 Ib ethephon) peracre peryear.

Page 10 of20

# GRAPES (Only in California andArizona)
GRAPES (TABLE GRAPES IN CALIFORNIAAND ARIZONA): An application of ETHREL

### ® brand Ethephon Plant Regulator promotes early unifonn color development on table grape varieties such as Cardinal, Emperor, Flame seedless, Red Malaga, Queen and Tokay allowing more efficient harvests ofquality fruil. 

### GRAPES (RAISIN PRODUCTION): A foliar spray of ETHREL

### ® brand Ethephon Plant Regulator will hasten maturity of Thompson seedless grapes resulting in reduced acids, increased sugars and increased raisin qualily.



### Crop Situation TABLE GRAPES 

### (such as Cardinal, Flame Seedless, Red Malaga, and Queen)

TOKAY GRAPES

RAISIN PRODUCTION (Thompson Seedless)


### Use Limitations Table Grapes 

### ETHREL® Pints/Acre



### 112-2



### 1-2

1-2 Specific Directions For high temperatures conditions (above 85°F) use lower rates of 

### 1/2 to 1 pinl peracre. For low temperatures condiflons (but above 65°F) use higher rates. Apply in sufficientwatertowet vines and fruit clusters uniformly, using convenlional ground sprayers. Treatwhen 

### 5 - 30% of berriesshowcolor. Treat Tokays when 

### 5 - 15% of berriesshowcolor. Apply as a foliar spray at 5% berry softening. Treat when 

### 5 - 30% of berries show color. 

### Remarks Harvest fruit at desired maturity and quality as indicated by sugar content, acidity and color. This is generally two weeks or more aftertreatment. Watch treated areas closely and harvest before berries become too dark. For more information regarding local experiences with this producton grapes, consult your 

## Fa"" Advisor DC Extension Viticulturist.



### A foliar spray of ETHREL® will hasten maturity of Thompson Seedless grapes resulting in reduced acids, increased sugars and increased raisin quality. For more information regarding local experience with this product on 

# Igrapes consullyour Farm Advisor or Extension Viticulturist.

Rates higherthan 1 pinUA may increase the incidence ofcracked fruit and should be used only in areas orduring weather conditions where grapes have been especially hard-to-color in past seasons. Some berry softening is associated with ETHREL®brand Ethephon Plant Regulator treatment of some varieties Vllhich may limit or influencestorage considerations. Do notstore Tokays. Do not harvestgrapes treatedwith ETHREL® brand Ethephon Plant Regulatorsoonerthan 14 days after last application. Do not exceed 2 pints ofthis product (0.5 Ib ethephon) per acre peryear. Raisin Production (Thompson Seedless) Do not applyto grapes understress from insectdamage or moisture stress. Observe treated vineyards closely and harvestat proper maturity as determined bysugar acid levels. Do notexceed 2 pints ofthis product (0.5 Ib ethephon) per acre peryear.

Page 11 of20

# PEPPERS

PEPPERS: A foliar spray of ETHREL® brand Ethephon Plant Regulator promotes early, uniform ripening and coloring for more efficient packing and handling offruit.


## ETHREL® Crop Situation Pints/Acre Specific Directions Remarks 

## PEPPERS 1 

### tl4-4 Thorough coverage is essential. For ground or air 

### Check several field locations to determine application choose equipment and spray volumes crop stage aod 

### degree of maturity. that will insure uniform coverage of foliage and fruit. ETHREL® treatments may reduce 

### total Use the higher rate 'Nhen cool temperatures are yields 

### if applied too early or there is a lack anticipated (less than 

### 65Q

### F), when plants 

## ace of uniform, mature, green 

### fruit resulting 

### growing vigorously or when foliage is dense to 

### from split fruit set or variable soil cultural assure thoroughwetting ofall leaves and fruit. practices, Harvest fruit after desired color Use the lower rates 'Nith lo;ver spray volumes (1 1/4 

### and maturity, generally 14 or more days to 2 pint rate in 20 gallA) and higher rates with aftertreatment. higher volumes (3-4 pintSl40 gallA). The 3-4 pint rate in less than 40 gpa may cause foliage burn under hot dryconditions. Apply ETHREL® to bel! peppers when 10% of fruit are red and chocolate and to chili and pimento pepper varieties when 10 to 30% of fruit are red and chocolate and there is sufficient mature green fruit to produce desired tonnage. ETHREL® will not ripen immature, qreen fruit. 

### Use Limitations

Do notapply Vllhen prolonged average high temperatures of95°F after treatment are expected. Do nottreatwhen temperatures exceed 10Q°F. Applications made under high temperatures 'Nill accentuate fruit ripening, yellowing of foliage, defoliation and immature fruit abscission. Do not treat when average temperatures are below 60°F. Low temperatures after treatment may reduce or negate the effects of ETHREL® 

### brand Ethephon Plant Regulator. Some yellowing and general aging ofleaves will be noted aftertreatment. Do notharvest peppers treatedwith ETHREL® 

### brand Ethephon Plant Regulator soonerthan 5 days after lastapplication. Do notexceed 4 pints ofthis product (1.0 Ib ai ethephon) per acre peryear. NOTE: Under certain conditions tank mixtures of ETHREL® brand Ethephon Plant Regulator with desiccants containing sodium chlorate could result in the formation of hypochlorous acidswhich on heating will emittoxic chloride fumes.

Page t20f20

# PINEAPPLEAND SUGARCANE

CROP AND RATE PER 

## SPRAY RESTRICTIONS 

# I USE ACRE 

### VOLUME APPLICATION TIMING SPECIFIC COMMENTS PINEAPPLE 

### Flower Induction t to 

### 2 pints 

### 100 to 

### 500 'Bearing 

### age' about 

### 12 Proper rate will vary with Do oot 

### graze pineapple ETHREL ® applied to 

### gallA months 

### after planting. local growing conditions, forage treated with pineapple plants will Generally about 6 months varieties, plantation ETHREL® Do not harvest stimulate uniform priorto desired harvest. management practices pineapples treated with initiation offlowering. and time of year. Use the ETHREL® 

### sooner than 2 

### higher rate where earlier days after the last harvest is desired. 

### Apply application. 

### when plneapple foliage is 

### d". Maturity 1/2

### to 2 tOO 

### to 300 When the first fruit begin U,e 

### a broadcast spray, Concentration pints gallA to change color. thoroughly cover both ETHREL® application foliage and fruit. Use the will stimulate uniform higher rate during periods shell color of cool or cloudy weather development when normal ripening has slowed. SUGARCANE
Flower Prevention 1/2 pint 7 gallA Just prior to flower Apply by fixed wing oc Do not harvest sugarcane ETHREL® application minimum initiation. helicopter using equip- treated with ETHREL® will prevent or reduce ment designed to give sooner 

### thao 2 months flowering and pithy uniform coverage. after the last application. tissue formation. Actual biomass increase Do not graze sugarcane will be affected by the time forage treated with Biomass Increase between treatment 

### aod ETHREL®. ETHREL ® used to harvest. preventflowering can Consider anticipated also result in ceincreased biomass coverable sugars as well accumulation and as biomass to determine recoverable sugar optimum harvest date. For Use in Hawaii Only. yield. """-_

### ....

Page t3 of20

# TOBACCO (Flue-Cured Only)
TOBACCO (FLUE.CURED): A foliar spray ofETHREL®brand Ethephon Plant Regulator promotes early. uniform "yellowing" ofmature 

### tobacco. ETHREL

### ® reduces curing time, allowing more efficient use of curing barn space, and increased control over harvest schedules, 

### ETHREL

### ® brand Ethephon Plant Regulator increases the capacity of the curing barn by shortening the curing time and allows adjustments in harvest schedules. ETHREL 

### ®can be used as a directed spray to the bottom or middle portion ofthe tobacco plant oras an over-Ihe-top spray. ETHREL 

### ® is not intended or recommended for use on immature tobacco.


## ETHREL® Crop Situation Pints/Acre 

### Specific Directions DIRECTED 

### 4 Use drop nozzles. Choose TG orDC spray tipsdesigned to apply 50

- 60 gpa at 35-40 psi and at SPRAY tractor speed of 2-3 mph. Use 2 nozzles per row; one on each side of the row dropped low APPLICATION enough to direct the spray to the leaves to be ripened and harvested. Thorough spray coverage is essentiaL With a directed spray, be sure to harvest all leaves with 20% or more vellowina. OVER-THE-TOP 

### 4-8 Treat only when leaves remaining on the stalk are mature. To ensure remaining leaves are APPLICATION mature, test spray several tobacco plants as described under the section "Application Timing". Use the lower rate in a normally mature crop when experience indicates that minimum ripening inducement is required. Use the higher rate when the crop is heavy and has a tendency to be more rank or when temperatures are lower than normal. Always test spray to determine if the tobacco is mature enough to respond to treatmentwith ETHREL ®. Apply over-the-top ETHREL® spray as a fine mist using three nozzles (one nozzle tips over the center ofthe plant, and one on each side) to assure all leaves are covered thoroughly, similarto the application pattern ofsystemic suckercontrol agents. Use a spray pressure of40 to 60 psi.


### USE LIMITATIONS Do not apply ETHREL ® brand Ethephon Plant Regulator to immature leaves as this can result in unsatisfactory coloring, weight loss and reduced leafquality.
Do not allow the crop to over ripen in the field after using ETHREL ® brand Ethephon Plant Regulator, since this may cause some reduction in yield and quality. Do not treat before anticipated majorstorm which could prevent harvest and result in crop loss. Do not apply ETHREL® brand Ethephon Plant Regulatorjf rain is expected within 6 hours.
Do not harvesttobacco treated with ETHREL ® brand Ethephon Plant Regulatorsoonerthan 2 days after application. Follow use rates listed above for labeled uses. Do notexceed 8 pints ofthis product (2 Ib ethephon) per acre peryear. 

### APPLICATIONTIMING Successful results with ETHREL® brand Ethephon Plant Regulator call for treatment when leaves are mature, not overly rank green when sprayed. To easily determine the propertreatment timing and the number ofleaves per stalk ready for harvest, test spray several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. Test leaves that fail to yellow in 72 hours are not mature and are not ready for ETHREL® treatment. Waita few days to permitfurther natural maturing, then make anothertest spray or"maturity" check. Determine acres to treat by first confirming the numberof leaves per plantthat will color, then use barn capacityto calculate the number ofacres to treat. A test spray can be prepared by mixing 4 teaspoons of ETHREL® brand Ethephon Plant Regulator in 1 quart ofwater. Apply about t ounce toeach test plantcovering all leaveswith a fine mist. ETHREL ®will notcolor immature leaves. To avoid quality loss and or possible leaf drop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. Limit use ofhigher rates to cool (below 65°F at the time oftreatment) slow ripening conditions. 

### WHEN TO HARVEST All mature, sprayed leaves will begin to color within 24 to 72 hours after ETHREL® application. The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest treated tobacco when leaves have reached the desired color intenSity.

Page 14of20

### Harvest can commence 48 hours after ETHREL ®brand Ethephon Plant Regulator application. To determine harvest timing and avoid quality loss or leafdrop, closely monitortreated crop and weather conditions. 

### CURING ETHREL® BRAND ETHEPHON PLANT REGULATOR TREATED TOBACCO Curing procedures are as much an art as a science and each cure must be judged on the basis of tobacco condition, interval between treatment and harvest, weather and type ofcuring facility before prescription temperature and ventilation schedules can be established. To obtain maximum quality, care must be 

### taken to observe and control the curing process closely, especially during the late "coloring" and early "drying" stages ofthe leaf. Ethephon treated tobacco will have started the coloring process when harvested, reducing the time required in the coloring phase of curing. Treated tobacco should be dried faster. Iftobacco leaves are green orcontain some green when harvested, it may be necessary to color them for a few hours. Ifthe leaves are completely yellow, temperature and ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried 

### (3/4 dry), you should follow normal procedures for curing. Since ETHREL® treated leaves cure faster, treated and untreated leaves should not be cured together in the same barn.



# TOMATOES
TOMATOES (PROCESSED): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates and concentrates tomato ripening increasing recoverable fruit yield from a once-over harvest. Plant Regulator application starts the normal ripening process earlier and increases the rate of ripening of mature green fruit concentrating maturity. Concentrated maturity enables high recoverable yields of ripe tomatoes in once-over harvest. Early concentrated maturity extends the normal harvest season and helps growers schedule harvestand handling more effectively. TOMATOES (FRESH MARKET IN CALIFORNIA): A foliar spray of ETHREL® brand Ethephon Plant Regulator accelerates tomato ripening increasing the early yields ofmarketable ripe fruit.
ETHREL® Crop Situation Pints/Acre Specific Directions Remarks PROCESS 

### 11/4-31/4 Apply 1 

### Xi to 3 

### Xi pints per acre of Apply ETHREL® 

### when desired tonnage of fruit has TOMATOES ETHREL® brand Ethephon Plant reached marketable size eod maturity. Check fields Early and Regulator in a minimum of 20 gallons closely for stage and degree of uniform maturity prior to Midseason Crops per acre for ground application and a application. Sample several plants throughout the field to
orWarm minimum of 10 gallons per acre for determine proper spray date. Sort, weigh and calculate Conditions aerial application. Apply when 5% to the percent fruit which is red and pink, including breakers. 15% of the fruit in the field are red Fruit size alone is not an adequate indicator. Observe and pink (including breakers) and specific directions to determine treatment stage for your there is sufficient mature green fruit to situation. Walk treated fields frequently to evaluate crop produce the desired tonnage. condition. Maintain normal cultural practice between Under high temperatures (above 85 treatment and harvest. Timely harvest is essential for F), rates as low as f 114 pints/acre maximum return of high quality fruit. Consult processor can be effective. representatives concerning delivery schedules eod Thorough coverage is essential. Foe 

### quotas priorto application of ETHREL ®. ground or air application choose Consult your local Bayer CropScience Representative, eqUipment and spray volumes that Extension Horticultural Specialist or Farm Advisor for will assure uniform spray coverage of suggestions on the proper use of ETHREL ®when fields foliage eod fruit. Overdosing from have variable plant vigor due to differences in soil overlapping swaths or spray nozzle conditions or cultural practices and for rates of fruit patterns can cause severe foliage ripening as affected by temperature, within the rate and injury. If bands are sprayed over the timing limitations shown on the label. row, reduce the amount of ETHREL® used 

# '0 proportion to the 

### area actuallytreated. Observe treated fields closely eod harvestfruit at proper maturity.

Page 15 of20

# TOMATOES (continued) 

### ETHREL® 

### CropSituation Pints/Acre Specific Directions Remarks 

### PROCESS 

### 31/4-61/2 Apply 3 

# :v. to 6 

### Y:i pints per acre of 

### ETHREl® brand Harvest at proper 

### maturity. 

### TOMATOES Ethephon Plant Regulator in a minimum of 20 gallons per Temperatures 

### above gO°F may 

### Late Season or acre for ground application and a minimum of 10 gallons cause fruit to ripen sooner whereas Coastal Crops or 

### per acre for aerial application. Apply when 5% to 30% of temperatures below 65° 

### F retard Cool Conditions 

### fruit in the field are red and pink (including breakers) and natural color development and may there is sufficient mature green fruit to produce the desired extend the time between treatment tonnage. Maximum response is achieved when fruit to be and harvest. treated is 5 

## to 15% pink and red. Use the higher rate of ETHREL ® when nighttime temperatures are cool (below 65°F) or vegetative growth is dense. Thorough coverage is essential. For ground or air application choose equipment and soravvolumes that 'hi)) 

### assure uniform sorav coveraoe FRESH MARKET 1114-5 Apply ETHREL ®when desired tonnage offruit has reached Check treated fruit frequently and TOMATOES marketable size and maturity, generally 3 to 6 days before harvest at desired maturity. 

### Whe, California desired harvest date. Expect only one harvest from treated programming harvest, spray a 

### areas. different block each day aod 

### Apply 1

### Y. to 5 pints per acre of ETHREL® brand Ethephon harvest blocks daily in the same Plant Regulator in a minimum of 40 gallons per acre for sequence. ground application and a minimum of 10 gallons per acre for aerial application. Thorough coverage is essential. For ground or air application choose equipment and spray volumes thatwill assure uniform spray coverage Use the higher rate and longer preharvest interval on late season crops, when temperatures are cool (generally below 85°F) and foliage is dense. Under high temperatures, rates as low as 1 1/4 

### pints per acre have been effective while reducing foliage damage particularly on more sensitive varieties

- see above. 

### Use Limitations Do not apply before1here is sufficient mature green fruit to produce the desired tonnage. ETHREL® brand Ethephon Plant Regulator will not ripen immature green fruit. Someyellowing and general aging offoliage may be observed following treatment. Do not treat plants with poor root systems or growing under stress due to poor soil conditions, drought, disease or insect damage. Treatment ofweak plants will result in rapid loss offoliage cover increasing sunburn and sun scald potential, especially under high temperature conditions. Do not treatwhen sustained temperatures above 105°F are anticipated. Do not treat sensitive varieties during period when temperatures exceed 100°F. Foliar damage is more severe on certain varieties such as VF 10, VF 315, VF 145, 21-4, and 13L. During periods ofhigh temperatures use the lower rates on sensitivevarieties. Do nottank mixwith sun protection products, sun protection whiteners, spray adjuvants orother additives. Do not apply ETHREL®brand Ethephon Plant Regulatorto more acreage than can be harvested in 2 to 3days. Do not apply ETHREL® 

### brand Ethephon Plant Regulatorto varieties known to soften rapidly or shatterwhen ripe. Do not use on greenhouse tomatoes. Do not harvesttomatoes treated with Ethrel@brand Ethephon Plant Regulatorsoonerthan 3 days after last application. Follow use rates listed above for labeled uses. Do notexceed 6.5 pints ofthis product (1.63 Ib ethephon) peracre peryear.

Page 16 of20

# WALNUTS
WALNUTS IN CALIFORNIA: A foliar spray of ETHREL 

### ® brand Ethephon Plant Regulatorwill loosen walnuts for increased efficiency of mechanical harvest, promote earlier harvest, improve hull removal, and increase recoverable yields from a**once~over** harvest


### Crop ETHREL® 

### Specific Directions 

### Situation PintsfAcre Expect best results with spray concentrations of California 

### 3-5 300 

### to 900 

### ppm. Refer to spray 

### ETHREL® preparation chart below. Under low temperatures andfor 

### low humidity conditions use the higher label rates. Expect less time between application and harvest with higher label rates. For best results treatwhen airtemperatures are between**60~F** 

### aod**95~F.** Expect reduced effectiveness if above gO°F with low humidity due to spray evaporation. Thorough uniform coverage of walnut hulls is essential foc maximum hull split and nut loosening response. Choose equipment that provides maximum spray penetration of the entire tree canopy. 

### U" large air carrier sprayers 'Nhere tree sizejeopardizes coverage. Orvolute sprayerattachments may help.



### USE LIMITATIONS Treatmentpriorto packing tissue brown (mature) stage may reduce nutquality. Some leafdrop is associatedwith treatment. 

### Remarks
Walnuts 

### are mature when the packing tissue between kernel 

### halves completes browning. 

### Collect nut samples from throughout the tree canopywhen determining percent nut maturity. Advancing Harvest

- Apply when 95-100% ofthe nuts have reached maturity. Inspect frequently 

### aod harvest 

### a, soon 

### a, adequate hullability occurs generally 10-16 days after treatment depending 00 variety and weather conditions. Plan second shake 10-12days afterfirst shake. Once Over Harvest

- Variety, growing conditions and weather affect maturity and the opportunity for once over harvest. Contact a local fieldman or Farm Advisor to determine if once over harvest 

### cao ba expected ;0 your situation. Apply to mature walnuts 10 days priorto expected harvest date. Expect actual harvest 

### to range from 7-t2 days after treatment.

Do nottreat diseased, low vigorormoisture stressed trees as excessive leafdrop may occur. Assure that dosage rates are measured accurately since rates higher than recommended may result in tree injury (such as excessive defoliation, reduced catkin formaUon and twig dieback). Do not harvestwalnuts treated with ETHREL ® soonerthan 5 days after last application. Do not exceed 5 pints ofthis product (1.25 Ib ethephon) per acre peryear.

ETHREL@SPRAY PREPARATION CHART**Sl2ra~** Volume (gallons/acre) ETHREL® Rate 

### 100 

### 200 300 400 PintsfA LbsfA Concentration (pl2m) 

### 3 0.75 

### 900 450 300 

# -- 4 1.00


## --- 600 400 300 5 1.25


## -- 750 500 375 500



## -

--- 300

Page 17of20

# MISTLETOE REMOVAL
DWARF AND LEAFY MISTLETOE REMOVAL: A foliar spray of ETHREL® brand Ethephon Plant Regulator will remove dwarf mistletoe shoots in ornamental conifers and leafymistletoe from ornamental deciduous trees.



### ETHREL® 

### Crop Situation 

### Amount 

### DWARF 2 pints MISTLETOE ON 

### pee 

## ORNAMENTAL 20 gallons CONIFERS DOUGLAS FIR 

### 1 pint ORNAMENTALS 

### pee 20 gallons

LEAFY 2 quarts MISTLETOE 

### pee ON 

### 20 gallons ORNAMENTAL DECIDUOUS TREES Specific Directions 

### Remarks Apply as a foliar spray to dwarf Applications made in conjunction with sylvicultural mistletoe shoots before mistletoe mistletoe management 

### will prevent spread of the 

### seed dispersal. 

### Foe effective 

### mistletoe parasite to other parts of the tree and removal, all mistletoe shoots must 

### othertrees. be sprayed to wet. Use of a non- Mature needle drop, that normally occurs in the ionic 

### surfactant 

### at recommended fall, may be hastened bythe use of ETHREL®. 

### rates may increase effectiveness. Treat any mistletoe regrowth before Applications of higher rates on Douglas fir may seed dispersal. result in excessive needle drop. Make applications afterfall leafdrop Large mistletoe infections and mistletoe found in through mid-winter. 

### Foe effective mesquite may be difficult to control with a single removal, all mistletoe shoots must application and retreatment may be necessary. be sprayed to wet. Use of a nonionic surfactant 

### at recommended rates may increase effectiveness. Any mistletoe regrowth should be treated during 

### the labeled application window.


# FRUIT ELIMINATION (Ornamental Use Only)
UNDES!RABLE FRU!T ELIMINATION: A foliar spray of ETHREL® brand Ethephon Plant Regulator will reduce or eliminate undesirable fruit development on apple, crabapple, carob and olive trees.

ETHREL® Crop Situation Amount Specific Directions Remarks APPLES 8 to 12 ounces Apply as a foliar spray at the flower Application must be made before fruit set for best CRABAPPLES 

### pee bud to full bloom stage, prior to fruit results. set. Wet foliage thoroughly. Over Do not treat weak trees or trees under stress 20 gallons application 

### of ETHREL® Plant (drought, insect or disease damaged trees) as Do notexceed 12 Regulator can result in excessive excessive leafdrop ortwig drop can result. ounces (0.15 oz. leaf drop andlor tree defoliation.

ai/gallon) per 

### U,e higher rates when Some leaf drop or temporary leaf yellowing may application. temperatures are cool. occur after treatment. CAROB 6 ounces App!y 

### a, a foliar spray. Wet all Do not use on small 

### eed fruited varieties of (Cerafonia 

### siliqua) 

### pee foliage thoroughly. Amount of spray crabapple 

### a, fruit elimination will 

### oot be 20 qallons will depend on tree size. satisfactory.
OllVE* 12 ounces (Olea europaea) 

### pee 20 qallons *This recommendation is not intended to be used on commercial fruit production as a thinning agent.

Page 18 of20

# TURF

An application ofEthrel slows the growth ofturfgrasses thus reducing the required frequency ofmowing and the volume ofclippings collected.

SITES 

## RATE APPLICATION SPRAYVOLUME Fairways, Roughs & Commercial 6f1ozJ1,QOOsqft Apply to activelygrowing turf. 

### !twill 

### 0.5-4.0 galsf1,OOO sq

### ft Turfgrasses, including Bentgrass require 

### 7-10 daysfor ETHREL®to (Fairwaycut), Kentucky act. Reapplicatfon intervals: Bluegrass, Perennial Ryegrass, Kentucky Bluegrass-7 wks. Tall & Fine Fescue Perennial Ryegrass-7 wks. TalifFine Fescue-4 wks. 8enlQrass-4 wks. 

### Use Limitations:

Do notallow entryto treated areas until sprays have dried. Forbest results, applywith sprayer in sufficient volume ofwaterto provide uniform coverage. ETHREL® is foliarly absorbed. Apply onlyto actively growing turf, underfavorable growing conditions, that is notgoing into a dormancy period. Do not treatturfgrass with poor rootsystems orgrowing under stress due to poor soil conditions, drought, disease or insectdamage. Do not apply to golfcourse greens. Use ofspreaders/stickers with ETHREL® is not necessary. ETHREL® is an acidic product and prolonged exposure to spraydeposits will damage acrylic plastics. certain paints and metals. Rinse thoroughlyall exposed acrylic plasUc materials and painted surfaces with a detergent and waterwithin one hourafterexposure to spraydeposits.
Testtankmixeswith otherproducts on a small area before using widely.

Page 19of20

## IMPORTANT: READ BEFORE USE Read the entire Directions for Use, Conditions, Disclaimer ofWarranties and Limitations of Liability before using this product. Ifterms are not acceptable, return the unopened product container at once. By using this product, useror buyer accepts the following Conditions, Disclaimer ofWarranties and Limitations ofLiability. 

### CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it 

### is impossible to eliminate all risks associated with the use ofthis product. Crop injury, ineffectiveness or other unintended consequences may result because ofsuch factors as weather conditions, presence ofothermaterials, or the manner of use or application, all ofwhich are beyond the control ofBayer CropScience LP. AI! such risks shall be assumed by the userorbuyer. DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE LP MAKES NO OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL No agent of Bayer CropScience LP is authorized to make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENTWITH APPLICABLE LAW, BAYER CROPSCIENCE LP DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, SHALL NOT EXCEED THE PURCHASE PRICE PAID, ORAT BAYER CROPSCIENCE LP'S ELECTION, THE REPLACEMENTOF PRODUCT.



# NET CONTENTS:

ETHREL is a registered trademark of Bayer.

Produced for

Bayer CropScience P.O. Box t2014, 2 T.W. Alexander Drive Research Triangle Park, North Carolina 27709

ETHREL® brand Ethephon Plant Regulator (Pending) 

### 01f20f10.

Page 20 of20

## UNITED STATESENVIRONMENTALPROTECTIONAGENCY WASHINGTON, D.C. 20460



## OFFICEOF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES MEMORANDUM
DATE: 24JUNE2009


## SUBJECT: ETHEPHON-Human, Occupational ExposurefRiskAssessmentforthe Use ofEthephonon Greenhouse Tomatoes

PCCode: MRIDNo.: 

### Petition No.: 0998011 

### None None DP 

### Barcode: 0366154 EPAReg. No. 264-267 Regulatory Action: Section 24(c) AssessmentType: ORE TXRNo.: None Reregistration CaseNo.: None CAS No.: None



## FROM:

THROUGH:

TO: Mark 

## I. Dow, Ph.D., Biologist

# ~A-u Alternate Risk Integration

# Asstlf~!;:am (ARIA) RiskIntegrationMinorUse & 

## EmergencyResponseBranch (RIMUERB) RegistrationDivision(RD) 7505P
JohnC. Redden, ARIATeam Leader RlMUERB/RD 7505P TonyKish HerbicidesBranch RD 7505P
INTRODUCTION
Underprovisionsin Section24(c) oftheFederal Insecticide, Fungicideand Rodenticide Act (FIFRA), as amended,the BayerCropScience LPhasrequested registration ofthe plantgrowthregulatorethephonfor use on "large-fruited greenhousetomatoes" 

## inthe State ofPennsylvania.
The risk assessmenttechniques used in thisdocument are thosethathave beendeveloped and refined bythe RED/Office ofPesticide Programs' SciencePolicyCouncil for Exposure (ExpoSAC). RDherein utilizesthe sametechniques as are HED's standard operatingprocedures (SOP).

## USE PATTERNSUMMARY
Theproductfor which 24(c) registrationhas beenrequestedisETHREL®

## brand EthephonPlantGrowth Regulator, EPAReg. No. 264-267. Chemically, ethephonis knownas [(2-chloroethyl)phosphonicacid]. ETHREL®

## is formulated as a 2.0 Ib active 

## ingredient (ai)pergallon liquid. According to draft24(c) Supplemental Labeling,theuse isintendedfor "large-fruitedgreenhouse tomatoes (greaterthan 1"indiameter)". "Lateseason"applications shouldbemadewhen fruit are ofmarketable size. The rate of 

## applicationis 1.25

- 5.0 

## pintsoffonnulationiA (0.3125-1.25 Ib ail A). Forthese applications,thematerialmay be sprayedonthe plantfoliage or"painted"onwitha brushorspongeonthe stem inthe areajustbelowthe 

## fruit. Higherrates shouldbeused 

## for brush/sponge applications.
"Directionalapplications"may be made to aid inunifonnmaturationofclustertomatoes orindividual fruit withirregularmaturation. Inthis case, applications shouldbemade directlyto fruit. The label stated rate ofapplicationis 0.15-3.5 mlformulationiL ofspray (0.005-0.12 fl ozJO.56 

## pint) It

## should be buffered to apHof6.0.


## There is a 24hourpreharvestinterval (PHI).
OCCUPATIONALPESTICIDEHANDLEREXPOSURE
Basedupontheproposedusepattern, RD believesthemosthighlyexposedoccupational pesticidehandlers willbe I)mixer/loader/applicators using open-pourloadingofliquid fonnulation and applying with lowpressure hand-wand sprayersand2) mixer/loader/applicatorsusingthe "paintbrush"or"sponge on" method ofapplication.
RD also believes occupationalhandlers will be exposedto short-tenndurationexposures (l

- 

## 30days). Private (Le., grower) applicatorsmayperfonnall functions, that is, mix, loadand apply the material. TheExpoSAC SOPNumber 12 (29 March 2000) 

## directs thatalthough the same individualmayperform all thosetasks, they shall be assessed separately. The availableexposuredatafor combined mixer/loader/applicator scenarios
arelimitedincomparisonto the monitoringofthese activities separately. These exposure scenarios are outlinedinthePesticideHandlerExposure Database(PHED) SurrogateExposure Guide (August 1998). HED has adopted amethodologyto present the exposure andrisk estimates separatelyfor thejobfunctions in some scenariosandto presentthemas combined inothercases. Mostexposure scenarios forhand-held equipment (such ashand wands, backpack sprayers, andpush-type granular spreaders)
are assessed as acombinedjobfunction. Withthesetypes ofhandheldoperations, all handling activities are assumedto be conductedbythe same individual. Theavailable PHED and other exposure data support this and HEDpresents them inthis way. Conversely, for equipment types suchas fixed-wing aircraft, grOlmd-boom tractors, or air-blast sprayers,the applicatorexposuresare assessed andpresented separately from those ofthe mixers and loaders. By separating thejobfunctions, HED/RD detenninethe most appropriate levels ofpersonalprotective equipment(PPE) foreachaspect ofthejob without requiring an applicatorto wearunnecessary PPEthatmightberequired fora

2

## mixerlloader (e.g., chemical resistant gloves mayonlybe necessaryduringthepouringof
a liquid formulation).
Nochemical specific datawere availablewithwhichto assesspotential exposureto pesticidehandlers. The estimatesofexposuretopesticidehandlers are based upon surrogate studydataavailablein thePHED (v. 1.1, 1998). Forpesticidehandlers, itis HED standardpracticeto presentestimatesofdermal exposure for "baseline"thatis, for workers wearing a single layerofwork clothingconsistingofa long-sleeved shirt, long pants, shoesplus socks andno protective glovesas well asfor "baseline" and the use of protectivegloves orotherPPE as mightbenecessary. Theproductlabel directs applicators and other handlersmustwear long-sleeved shirt, longpants, shoesplus socks, chemical-resistant gloves made ofany waterproofmaterial suchas polyethylene or polyvinyl chlorideandprotective eyewear. However, due to the nature ofthismaterial, estimates ofexposure aremade only for handlers wearingprotective gloves, i.e., PHED data are used onlyfrom occupationalpesticidehandlerswearing gloves.
Thetoxicological factors usedin this assessment are taken from: Memo, B. Daiss, 10 MAY2006, DP Code 280690, "HEDRisk Assessmentfor Tolerance Reassessment EligibilityDecisionD328666

...." In theAgency's2006 assessment, dermal toxicological endpointswerenot determined. TheAgency stated: "The dermal exposure scenario was not assessed because ethephonishighlycorrosive and systemiceffectswere seenonlyat 150 mglkg/day, dosesthatwouldcause severe damagetothe skin (i.e., the corrosivenature ofethephon is expectedtopreclude dermal exposures at levelsthatmay cause systemiceffects). Atdermal doses above 150

## mglkg/day, ethephonis corrosiveto the skin. In arange finding study, dermally appliedethephonwaslethal above 500 mglkgldayandwas a severe irritant at 500

## mglkg/day. In the main 21-Dayrabbitdermal toxicity studyethephonproducedno systemictoxicity at 150mglkgldayor less,but causedlocal dennaltoxicity atdoses of25 mg/kglday and above. Since ethephonis dermally corrosive, exposures at levelshighenoughto cause systemic toxicity are not expected. Therefore, risk assessmentofdermal exposuresto ethephonwouldnotbe applicable.
TheHED HazardIdentificationAssessmentReviewCommittee (HIARC) selected an inhalationtoxicological endpointfrom a 28 day human clinical study basedupon cholinergic signs inhumans ofboth sexes following dailybolusdosing (capsule) atthe LowestObservedAdverseEffect Level (LOAEL) of 1.8 mg/kg/day. Theeffects seen were:diarrheaandincreased urgency andfrequency ofurination,loose stools, stomach cramps orgas. The LOAELis appropriate for all duration exposuresi.e., shortintennediate- and long-termexposures. Sincea Low ObservedAdverse EffectLevel is used versus a "No"effectlevel, an additional uncertaintyfactor (UF) of3Xis applied. A traditional lOX UF is appliedfor intraspecies variation. Thus, aMarginofExposure of 30 doesnotexceedthe Agency'slevel ofconcernforpotential exposures andrisks. See Table 1.0 for a summaryofestimatedoccupational exposures andrisks.

3

## The Agency's 2006 assessmentnotes: "Ethephonhas beentestedinrats and mice for oncogenic effects and was found negative." Thereforea cancer risk assessmentisnot necessary.

Table 1.0 SummaryofExposure & 

### Riskto OccupationalHandlers From Applying Ethephon to Greenhouse GrownTomatoes Unit Exposure I 

### Applic. Rate 1 

### Units 

# I Avg. DailyExposure 

# I MOE mg ai/lbhandled Ib ailunit TreatedJ 

### mg ailkg

### bw/day Mixer/Loader/Applicator**~**

### Liquid**~** 

### OpenPour**Low~pressure**

### /landwand lnha!. 0.Q3 

# I 1.25. 

# I 2Alday jlnhal. 0.00107

1 

### 1700 Ib 

### ailA PaintbrusllApplication Inhal. 

### 0284 2.0 Ib ailgal 2 cral/day Inhal. 0.0162 

### 110

I. Unit Exposures aretaken from "PHED SURROGA'fEEXPOSURE GUIDE", EstimatesofWorker Exposure from The Peslieide HandlerExposure Database Version 1.1, August 1998. Inhal. "" Inhalation. Units""mg a.i./pound of active ingredient handled. Unit Exposure for Paintbrush method is listed in HEDs StandardOpe/ating Procedures lor Residcntial ExposureAssessments Appendix B, page B-12. 2. Applie. Rate. ""Taken from 24(c) draftlabel. 3. UnitsTreated are taken from "Standard Values for Daily Acres Treated in Agriculturc'"; ExpoSAC SOP No.9.!. Revised 5July2000; as derived from product label. The label suggests a spray volumc0[20gallA for field grown tomatoes. The SOP indicates40gallonsper day may be applied via low-pressure hand-wand. Thus40 gal/day**~** 

### 20 gallA = 

### 2 Alday. Paint brush nlethod from Standard Operating Procedures (SOPs) torResidential Exposure Assessments. 18 DEC 1997, P62 Section 6.0 "Paintingand Wood Preservative Treatments 4. Average Daily Dose = 

### Unit Exposurc 

## *Applie. Rate 

## *UnitsTrealed -;.- 70 kg Body Weight 5. MOE = 

### Margin ofExposure = 

### LOAEL -;.- ADD.



## A MOE of30is adequateto protectoccupational pesticidehandlers from exposuresto ethephon. TheestimatedMOEs are all 

## > 30. Therefore, theproposed use doesnot exceed RD's level ofconcern.


## POST-APPLICATIONEXPOSURETOAGRICULTURALWORKERS
It

## is possible for agricultural workersto havepost-applicationexposureto pesticide residues duringthe course oftypical agricultural activities. Followingthe precedent set intheAgency's 2006 assessment,**post~application**

## dermal exposure to workers reentering treated areas are anticipatedbased onthe use patternsofethephon. However, since dermal exposure at dosesthatmaycause systemic effects are not expected due to the high corrosivityofethephon, no quantitative assessmentwas conducted. TheETHREL® 

## productlabel lists a 48-hourrestrictedentryinterval (REI), withanincreaseto**72~hours** 

## whenitis appliedoutdoors inarid areas. It

## shouldbe noted thatthepreharvestinterval listedonthe draft 24c label is 24 hours.



## RESTRICTEDENTRYINTERVAL (REI) Ethephonisclassified inAcute ToxicityCategory IV forAcuteInhalation. It

## is classified inCategory IIIfor acute delTI1al toxicity. Itis classifiedinCategoryI forPrimaryeye irritationand Primary skinirritation. It

## islisted as a delTI1al nonsensitizer. Thereforethe

4

## interimWorkerProtection Standard(WPS) REI of48 hr is adequatetoprotectagricultural workersfrom post-applicationexposures. Theproductlabel lists a48 hr

## REI.

5

## ATTACHMENT

, 

## AcuteToxicitvofEtheohon
Guideline MRlD#(S). 

# I No. 

### StudyType Results Toxici!yCategory 

## i 870.1100 Acule Ora! , 41154501 

### LDso"'" 3030mglkg III 

### I

, 

## 870.1200 Acute Dermal 4[154502 LDso = 1560 mglkg 

### 111 

### i

, 

### ---.j 870.1300 Acute Inhalation 41154504 LC,o = 4.53 mgfL 

### I IV 

## 870.2400 Primary Eye Irritation 

### Not required Assumed Corrosive 

### I 

### 870.2500 Pnmary Skin Irritation 

### 00029514 Corrosive 

## 870.2600 Dermal Sensilizalion 41 [54503 

### Nonscnsitizer Nonscnsitizcr



## SummaryofToxicologicaJDoseandEndpointsforEthephonforUseinHumanRiskAssessment ExposureScenario 

## Doseused in FQPASFand 

## StudyandToxicologicalEndpoint RiskAssessment EndpointforRisk UF Assessment 

## Acute Dietal)'**LOAEL~** 

## 1.8**FQPASF~** 

## 1 28-DayHuman Clinical Study LOAEL = 

## 1.8 

## general QOQulation mg/kg/day**aPAD~**

## -.lJ> mg/kg/daybased on diarrhea and increased**UF~30** 

## 30 urgencyand frequency ofurination, loose**~** 

## 0.06 mg/kg/day stools, stomach cramps or gas LOAEL

- 1.8 FQPASF-I 28-DayHuman Clinical StudyLOAEL

- 1.8 Chronic Dietary mg/kg/day aPAD**~** 

# lJ! mglkglday based on diarrheaand increased general QOQulation**UF~30** 

## 30 urgencyand frequency ofurination, loose**~** 

## 0.06 mg/kg/day stools, stomach cramps orgas Short/intennediate-Tenn LOAEL- 1.8 LOC for**MOE~** 

## 30 28-Day Human Clinical Study LOAEL

## = 1.8 Incidental Oral mg/kg/day mg/kglday based on diarrheaand increased (I

## day

- I month) urgency and frequency ofurination, loose stools, stomach cramps orgas Short-TennDennal

(I 

## day- I month) NotApplicable

-No exposure effects expected due to 

## demlal corrosivityofethephon Short/intenned/long

-Tenn**LOAEL~** 

## 1.8 LOCfor**MOE~** 

## 30 28-Day Human Clinical Study LOAEL 

## = 1.8 Inhalation mglkg/day Short-Term for mg/kg/daybased on diarrhea and increased (1-30 days, 1-6 mas, > 

## 6 Residential urgency and frequency ofurination, loose mas) and Occupational stools, stomach cramps or gas SummaryofToxicitytakenfrom: Memo, 

## B. Daiss, 10MAY 2006, DP Code 280690, "HEDRiskAssessmentfor Tolerance Reassessment Eligibility DecisionD328666

...."
cc:MDow(RIMUERB) RDl:J. Redden. K. Lowe M.LDow:S7824:PYI:(703)305-5533:RIMUER8:7505P



### 6

## ETHEPHON: MAGNITUDEOFTHERESIDUE ONTOMATO (GREENHOUSE)

IR-4PRNo. 00250

DataRequirement U.S.EPAOPPTS 860 Series Guidelines



## Author Keith Dorschner, Ph.D. IR-4Project Rutgers, The StateUniversity ofNewJersey 500 CollegeRoadEast, Suite 201 W 

## Princeton, NJ 08540

Study Completedon 

## Seepage7 for Study 

## Director's signature

PerformingLaboratories See page5 for listofperforminglaboratories

AnalyticalLaboratoryIdentificationNumber 00250.05-NYR08 FieldIdentificationNumbers 00250.05-C0I3 00250.05-FL37 00250.05-TX25

Ethephon: Magnitude 

### oftM Residue on Tomalo (Greenhouse) !R-4 PR No. 00250 Page 1 of 139