UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON D.C., 20460

MEMORANDUM SUBJECT:

TO:

FROM:

REVIEWED BY :

APPROVED BY : OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION PC Code: 129093 DP Barcode: 420682 June 12, 2014 Registration Review: Preliminary Ecological Risk Assessment and Endangered Species Effects Determination for Chlorfenapyr Margaret Hathaway , Chemica l Review Manager Tom Myers, Team Leader Risk Management and Implementation Branch II Pesticide Re-evaluation Division (7508P)**t/l~f("** Stephen P. Wente, Ph.D. , Biologist

# ~~ Environmental Risk Branch I Environmental Fate and Effects Division (7507P) Meghan Radtke , Ph.D. , Acting RAPL

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# /I)..//'( Environmental Risk Branch I Environmental Fate and Effects Division (7507P) 

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# J Sujatha Sankula, Ph.D., Branch Chief ( F--_ \.\.:

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### ;:::::;::::= Environmental Risk Branch I Environmental Fate and Effects Division (7507P)
Chlorfenapyr is an**insecticide mit~cide**  with currently registered uses confined to greenhouses , where it i s applied to indoor food and non-food crops, and structura l uses , where it is used as a termiticide and crack and crevice treatment. In the Preliminary Work Plan ( PWP; USEPA 2010a) for chlorfenapyr (CAS No. 122453-73-0 ; PC Code 129093) and Chlorfenapyr Problem Formulation (USEPA 2010b ; DP 383511), the Agency anticipated conducting a comprehensive ecological risk assessment in support ofthe Regi stration Review of chlorfenapyr, including an endangered species assessment, for all us es of chlorfenapyr and it s metabolites of concern. However, due to a label amendment exp lained below and re-examination ofpotential environmental exposure, the Agency has determined that there is no environmental exposure, and therefore there is no risk to non-target organisms. Based on this , the Agency has come to a No Effect determination regarding chlorfenapyr's impact on federally listed threatened and endangered species (hereafter referred to as " listed" species). Based on this same l ogic, no effects are expected for non-li sted species as well. The registration review docket for chlorfenapyr is EPA-HQ -OPP

- 2010-0467.



### 1The Agency typically evaluates the likelihood of an adverse effect, 

### i.e. , risk , us ing a quantitative approach where conservative exposure estimates are compared to the most s ensitive toxicity endpoints. However, in the case of chlorfenapyr, there is a lack of a complete exposure pathway from the use site to non-target terrestrial and aquatic organism s. The first use identified in the PWP as having potential outdoor environmental exposure was application to fruiting vegetables grown in a greenhouse. The Agency believed that exposure could occur because the label stated to "Compo st any discarded plant mate rial that has been treated." Following publication of the PWP , the registrant amended the label to prohibit com posting of chlorfenapyr-tr eated material. Therefore, the Agency has determined that this use no longer results in outdoor environmental exposure and a comprehens ive ecological ri sk assessment for this use is not needed. The second use identified in the PWP as having potential outdoor environmental exposure was application to soil underlying a concrete s lab prior to the s lab being poured (during construction). The PWP stated that there is a potential for expos ure to chlorfenapyr in adjacent areas via runoff from the use site if a major rain event occurred after application, but prior t o pouring the concrete slab. After re - examining thi s use pattern, the Agency has determined that the potential for outdoor environmental exposure is negligible

. This is because only a small area would be treated before the concrete is applied, and the time between application and pouring ofthe concrete slab would be minimal. Therefore, the Agency conc lu des that outdoor environmenta l exposure would not occur as a resu lt of thi s use and would not lead to ecological risk. All other chlorfenapyr use sites are indoors and result in no complete environmental exposure pathways, or are crack and crevice treatments with little potential for outdoor re lease. Based on incomplete exposure pathways for all chlorfenapyr uses, the Agency makes a No Effects (NE) determination for all listed species as well as a No Habitat Modification determination for all designated critical habitats for the currently registered uses ofchlorfenapyr. If, in the future, chlorfenapyr is considered for additional uses that could result in environmental releases, further analysis wi ll need to be undertaken to determine potential effec ts to non-target organisms, including li sted species and their designated crit ical habitat. REFERENCES USEPA. 2010a. Chlorfenapyr Preliminary Work Plan. Office of Pe sticide Programs, United States Environmental Protection Agency. Washington, D.C

. June 17,2010. USEPA. 2010b. Registration Review: Problem Formula tion Revised Based on Public Comments for Ecological Risk, Environmental Fate, and Endangered Species Assessments for Chlorfenapyr (PC Code 129093). Office ofPesticide Programs, United States Environmental Protection Agency. Washington, D.C. October 28, 2010. (DP Barcode: 383511)

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