**UNITED        STATES**

**SECURITIES        AND EXCHANGE COMMISSION**

**FORM        10-K/A**

| x                                                                                                | ANNUAL                  REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE                  ACT OF                  1934 |
|--------------------------------------------------------------------------------------------------|-----------------------------------------------------------------------------------------------------------------------------------------|
|                                                                                             |                                                                                                                                    |
| For                  the fiscal year ended December 31, 2007                                     |
|                                                                                             |
| OR                                                                                               |
|                                                                                             |
| o                                                                                                | TRANSITION                  REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT                  OF 1934         |
|                                                                                             |                                                                                                                                    |
| For                  the transition period from ______________ to                  _____________ |

**PHOTOMEDEX,        INC.**

| Delaware                                                                                        |   | 59-2058100                                                            |
|-------------------------------------------------------------------------------------------------|--------|-----------------------------------------------------------------------|
| (State                  or other jurisdictionof                  incorporation or organization) |   | (I.R.S.                  EmployerIdentification                  No.) |

| Title                  of each class |   | Name                  of each exchangeon                  which registered |
|--------------------------------------|--------|----------------------------------------------------------------------------|
| None                                 |   | None                                                                       |

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| Large accelerated filer  o           | Accelerated filer  o    |
|-------------------------------------------|-----------------------------------|
| Non-accelerated filer    o | Smaller reporting company  x |

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**Explanatory        Note**

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**PART          II**

**Item        9B.**
**        Other Information**

*Long-term        Debt*

**PART        IV**

**Item        15.  Exhibits**

|   | (b) | Exhibits |
|--------|-----|----------|

| 2.1    |   | Agreement                  and Plan of Merger, dated September 25, 2002, between PhotoMedex,                  Inc., J                  Merger Corp., Inc. and Surgical Laser Technologies, Inc.                  (1)         |
|--------|--------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 2.2    |   | Agreement                  and Plan of Merger, dated December 1, 2004, between PhotoMedex,                  Inc., Gold                  Acquisition Merger Corp. and ProCyte Corporation (2)                                 |
| 2.3    |   | Securities                  Purchase Agreement, dated October 31, 2006, by and between PhotoMedex,                  Inc. and each purchaser a party thereto (3)                                                              |
| 3.1(a) |   | Restated                  Certificate of Incorporation, filed on August 8, 2000 (4) (Exh                  3.1)                                                                                                               |
| 3.1(b) |   | Amendment                  to Restated Certificate of Incorporation, filed on January 6, 2004                  (5)                  (Exh 3.2)                                                                                |
| 3.2    |   | Amended                  and Restated Bylaws , (5) (Exh 3.1E)                                                                                                                                                                |
| 3.2(a) |   | Amended                  Section 6.01 of the By-laws, October 30, 2007 (20)                                                                                                                                                  |
| 10.1   |   | Lease                  Agreement dated May 29, 1996, between Surgical Laser Technologies,                  Inc.                  and Nappen & Associates (Montgomeryville, Pennsylvania) (5)(Exh                  10.31) |
| 10.2   |   | Lease                  Renewal Agreement, dated January 18, 2001, between Surgical Laser                  Technologies, Inc. and Nappen & Associates (5)(Exh                  10.32)                                     |
| 10.3   |   | Lease                  Agreement, dated July 10, 2006, PhotoMedex, Inc. and Nappen &                  Associates (6)(Exh 10.3)                                                                                           |
| 10.4   |   | Lease                  Agreement (Carlsbad, California) dated August 4, 1998                  (7)                                                                                                                       |
| 10.5   |   | Standard                  Industrial/Commercial Multi-Tenant Lease - Net, dated March 17,                  2005                  (Carlsbad, California)(8)(Exh 10.52)                                                        |
| 10.6   |   | Industrial                  Real Estate Lease, dated May 3, 2007, and delivered December 14,                  2007                                                                                                           |
| 10.7   |   | License                  and Development Agreement, dated May 22, 2002, between Surgical                  Laser                  Technologies, Inc. and Reliant Technologies, Inc. (5)(Exh                  10.7)            |
| 10.8   |   | Secured                  Promissory Note, dated May 22, 2002, between Surgical Laser Technologies,                  Inc. and Reliant Technologies, Inc. (5)(Exh 10.8)                                                        |
| 10.9   |   | Security                  Agreement, dated May 22, 2002, between Surgical Laser Technologies,                  Inc.                  and Reliant Technologies, Inc. (5)(Exh 10.9)                                            |
| 10.10  |   | Agreement                  as to Collateral, dated May 22, 2002, among Surgical Laser Technologies,                  Inc., Reliant Technologies, Inc. and AmSouth Bank (5)(Exh                  10.10)                       |
| 10.11  |   | Master                  Purchase Agreement, dated September 7, 2004, between PhotoMedex,                  Inc. and                  Stern Laser, srl (9)                                                                     |
| 10.12  |   | Master                  Lease Agreement, dated June 25, 2004, between PhotoMedex, Inc.                  and GE                  Capital Corporation. (10)                                                                    |
| 10.13  |   | Investment                  Agreement, dated March 30, 2006, between AzurTec, Inc. and PhotoMedex,                  Inc. (11)(Exh 10.56)                                                                                     |
| 10.14  |   | License                  Agreement, dated March 30, 3006, between AzurTec, Inc. and PhotoMedex,                  Inc. (11)(Exh 10.57)                                                                                        |
| 10.15  |   | License                  Agreement, dated March 31, 2006, and effective April 1, 1006, between                  Mount Sinai School of Medicine and PhotoMedex, Inc.                  (12)                                    |
| 10.16  |   | 2005                  Equity Compensation Plan, approved December 28, 2005                  (13)                                                                                                                             |
| 10.17  |   | 2005                  Investment Plan, approved December 28, 2005 (13)                                                                                                                                                       |
| 10.18  |   | Amended                  and Restated 2000 Non-Employee Director Stock Option Plan                  (1)                                                                                                                      |
| 10.19  |   | Amended                  and Restated 2000 Stock Option Plan (1)                                                                                                                                                             |
| 10.20  |   | 2004                  Stock Option Plan, assumed from ProCyte (14)                                                                                                                                                           |
| 10.21  |   | 1996                  Stock Option Plan, assumed from ProCyte (14)                                                                                                                                                           |
| 10.22  |   | 1991                  Restated Stock Option Plan for Non-Employee Directors, assumed                  from                  ProCyte (14)                                                                                     |
| 10.23  |   | 1989                  Restated Stock Option Plan, assumed from ProCyte (14)                                                                                                                                                  |
| 10.24  |   | Amended                  and Restated Employment Agreement with Jeffrey F. O'Donnell, dated                  October                  30, 2007 (Previously filed)                                                            |
| 10.25  |   | Amended                  and Restated Employment Agreement with Dennis M. McGrath, dated                  September                  1, 2007 (Previously filed)                                                              |
| 10.26  |   | Amended                  and Restated Employment Agreement of Michael R. Stewart, dated                  September                  1, 2007 (Previously filed)                                                               |
| 10.27  |   | Employment                  Agreement of John F. Clifford, dated March 18, 2005 (2)                                                                                                                                          |
| 10.28  |   | Employment                  Agreement of Robin L. Carmichael, dated March 18, 2005                  (2)                                                                                                                      |
| 10.29  |   | Separation                  Agreement, effective June 30, 2006, between PhotoMedex, Inc. and                  John F.                  Clifford. (15)                                                                        |
| 10.30  |   | Restricted                  Stock Purchase Agreement of Jeffrey F. O’Donnell, dated January 15, 2006                  (8)(Exh 10.44)                                                                                   |
| 10.31  |   | Restricted                  Stock Purchase Agreement of Dennis M. McGrath, dated January 15,                  2006                  (8)(Exh 10.45)                                                                           |
| 10.32  |   | Consulting                  Agreement dated January 21, 1998 between the Company and R. Rox                  Anderson, M.D. (7)(Exh 10.4)                                                                               |

| 10.33  |   | Restricted                  Stock Purchase Agreement of Jeffrey F. O’Donnell, dated May 1, 2007                  (17)                                                                                                                         |
|--------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 10.34  |   | Restricted                  Stock Purchase Agreement of Dennis M. McGrath, dated May 1, 2007                  (17)                                                                                                                                  |
| 10.35  |   | Restricted                  Stock Purchase Agreement of Michael R. Stewart, dated May 1, 2007                  (17)                                                                                                                                 |
| 10.36  |   | Restricted                  Stock Purchase Agreement of Michael R. Stewart, dated August 13,                  2007                  (18)                                                                                                            |
| 10.37  |   | Amended                  and Restated 2000 Non-Employee Director Stock Option Plan, dated                  as of                  June 26, 2007 (17)                                                                                                |
| 10.38  |   | Amended                  and Restated 2005 Equity Compensation Plan, dated as of June 26,                  2007                  (17)                                                                                                               |
| 10.39  |   | Master                  Term Loan and Security Agreement, dated December 31, 2007 among                  PhotoMedex, Inc., CIT Healthcare LLC, as Agent and Lender, and                  Life                  Sciences Capital LLC, as Lender (19) |
|   |   |                                                                                                                                                                                                                                                |
| 22.1   |   | List                  of subsidiaries of the Company (20)                                                                                                                                                                                           |
| 23.1   |   | Consent                  of Amper, Politziner & Mattia P.C. (20)                                                                                                                                                                                |
| 31.1   |   | Rule                  13a-14(a) Certificate of Chief Executive Officer (19)                                                                                                                                                                         |
| 31.2   |   | Rule                  13a-14(a) Certificate of Chief Financial Officer (19)                                                                                                                                                                         |
| 32.1   |   | Certificate                  of Chief Executive Officer pursuant to 18 U.S.C. Section 1350,                  as adopted                  pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (20)                                             |
| 32.2   |   | Certificate                  of Chief Financial Officer pursuant to 18 U.S.C. Section 1350,                  as adopted                  pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (20)                                             |

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| (1) | Filed                  as part of our Registration Statement on Form S-4, as filed with                  the                  Commission on October 18, 2002, and as                  amended. |
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| (2) | Filed                  as part of our Registration Statement on Form S-4/A filed with                  the                  Commission on January 21, 2005, and as                  amended. |
|-----|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (3) | Filed                  as part of our Current Report on Form 8-K, dated November 6,                  2006. |
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| (4) | Filed                  as part of our Quarterly Report on Form 10-Q for the quarter ended                  June                  30, 2000. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------|

| (5) | Filed                  as part of our Annual Report on Form 10-K for the year ended December                  31,                  2002. |
|-----|------------------------------------------------------------------------------------------------------------------------------------------|

| (6) | Filed                  as part of our Annual Report on Form 10-K for the year ended December                  31,                  2006. |
|-----|------------------------------------------------------------------------------------------------------------------------------------------|

| (7) | Filed                  as part of our Registration Statement on Form S-1, as filed with                  the                  Commission on January 28, 1998, as                  amended. |
|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (8) | Filed                  as part of our Annual Report on Form 10-K for the year ended December                  31,                  2005. |
|-----|------------------------------------------------------------------------------------------------------------------------------------------|

| (9) | Filed                  as part of our Current Report on Form 8-K, dated September 10,                  2004. |
|-----|--------------------------------------------------------------------------------------------------------------|

| (10) | Filed                  as part of our Quarterly Report on Form 10-Q for the quater ended                  June 30, 2004. |
|------|-------------------------------------------------------------------------------------------------------------------------------|

| (11) | Filed                  as part of our Current Report on Form 8-K, filed on April 6,                  2006. |
|------|------------------------------------------------------------------------------------------------------------|

| (12) | Filed                  as part of our Current Report on Form 8-K, filed on April 10,                  2006. |
|------|-------------------------------------------------------------------------------------------------------------|

| (13) | Filed                  as part of our Definitive Proxy Statement on Schedule 14A, as filed                  with                  the Commission on November 15,                  2005. |
|------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (14) | Filed                  as part of our Registration Statement on Form S-8, as filed with                  the                  Commission on April 13, 2005. |
|------|-------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (15) | Filed                  as part of our Quarterly Report on Form 10-Q for the quarter ended                  March                  31, 2006. |
|------|---------------------------------------------------------------------------------------------------------------------------------------------|

| (16)   | Filed                  as part of our Quarterly Report on Form 10-Q for the quarter ended                  September 30, 2003.             |
|--------|--------------------------------------------------------------------------------------------------------------------------------------------|
|   |                                                                                                                                       |
| (17)   | Filed                  as part of our Quarterly Report on Form 10-Q for the quarter ended                  June                  30, 2007. |
|   |                                                                                                                                       |
| (18)   | Filed                  as part of our Quarterly Report on Form 10-Q for the quarter ended                  September 30, 2007.             |
|   |                                                                                                                                       |
| (19)   | Filed                herewith                                                                                                              |
|   |                                                                                                                                       |
| (20)   | Previously                filed                                                                                                            |

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**SIGNATURES**

|                               | PHOTOMEDEX,                  INC. |
|------------------------------------|-----------------------------------|
|                               |                              |
| Date:                  May 8, 2008 | By:                               | /s/                  Jeffrey F. O’Donnell |   |
|                               |                              | Jeffrey                  F. O’Donnell |
|                               |                              | President                  and Chief                  Executive Officer |

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