RESEARCH SAMPLE SAFETY DATA SHEET 

PRODUCT NAME: 4,5,6-Trichloropyridine-2-carboxylic 

acid 

Effective Date: 25-Sep-14

1 

1. PRODUCT AND COMPANY IDENTIFICATION: 

PRODUCT: 4,5,6-Trichloropyridine-2-carboxylic acid 

COMPANY IDENTIFICATION: 

2. HAZARDOUS IDENTIFICATIONS: 

EMERGENCY OVERVIEW 

Off-white odorless solid. May be harmful if inhaled, 

absorbed through skin or swallowed. Risk of serious 

damage to eyes. May cause skin irritation. Evacuate area. 

Keep upwind of spill. Toxic fumes may be released in fire 

situations. 

EMERGENCY PHONE NUMBER: 800-992-5994

3. COMPOSITION/INFORMATION ON INGREDIENTS: 

Component CAS/DR Number W/W%

4,5,6-Trichloropyridine2-carboxylic acid496849-77-5 85-95%

Water 7732-18-5 5-15%

4. FIRST AID: 

EYE: Wash immediately and continuously with flowing water 

for at least 30 minutes. Remove contact lenses after the 

first 5 minutes and continue washing. Obtain prompt 

medical consultation, preferably from an ophthalmologist. 

SKIN: Remove material from skin immediately by washing 

with soap and plenty of water. Remove contaminated 

clothing and shoes while washing. Seek medical attention if 

irritation persists. Wash clothing before reuse. Discard 

items, which cannot be decontaminated, including leather 

articles such as shoes, belts, and watchbands.

INGESTION: Call a treatment center or doctor immediately 

for treatment advice. Have person sip a glass of water if 

able to swallow. Do not induce vomiting unless told to do so 

by the poison control or doctor. Never give anything by 

mouth to an unconscious person. 

INHALATION: Move person to fresh air. If person is not 

breathing, call an emergency responder or an ambulance, 

and then give artificial respiration; if by mouth to mouth use 

rescuer protection (pocket mask etc). Call a poison control 

center or doctor for treatment advice. 

NOTE TO PHYSICIAN: No specific antidote. Treatment of 

exposure should be based on judgment of the physician in 

response to reactions of the patient. 

5. FIRE FIGHTING MEASURES: 

FLASH POINT: Not applicable 

METHOD USED: Not applicable 

FLAMMABLE LIMITS

LFL: Not determined 

UFL: Not determined 

EXTINGUISHING MEDIA: Foam, CO2, Dry chemical 

FIRE AND EXPLOSION HAZARDS: Foam fire 

extinguishing system is preferred because uncontrolled 

water can spread possible contamination. Toxic irritating 

gases may be formed under fire conditions. Combustion 

products can include and are not limited to: Carbon 

monoxide. Carbon dioxide. Nitrogen oxides. Hydrogen 

chloride. 

FIRE-FIGHTING EQUIPMENT: Use positive-pressure, selfcontained breathing apparatus and full protective 

equipment. 

6. ACCIDENTAL RELEASE MEASURES: 

ACTION TO TAKE FOR SPILLS: 

For solid or powder substances: sweep up small spills and 

place in a suitable container for reuse or disposal. 

Wash exposed body areas thoroughly after handling. 

Report large spills to on 800-992-5994.
RESEARCH SAMPLE SAFETY DATA SHEET 

PRODUCT NAME: 4,5,6-Trichloropyridine-2-carboxylic 

acid 

Effective Date: 25-Sep-14

2 

7. HANDLING AND STORAGE: 

PRECAUTIONS TO BE TAKEN IN HANDLING AND 

STORAGE: Keep out of reach of children. Do not swallow. 

Avoid contact with eyes, skin, and clothing. Avoid breathing 

vapors, spray mist or dusts. Handle in ventilated area. Wash 

thoroughly with soap and water after handling and before 

eating, chewing gum, using tobacco, using the toilet or 

smoking. Keep away from food, feedstuffs, and water 

supplies. Store in the original containers. 

8. EXPOSURE CONTROLS/PERSONAL PROTECTION: 

These precautions are suggested for conditions where a 

potential for exposure exists. Emergency conditions may 

require additional precautions. 

EXPOSURE GUIDELINES: None established. 

ENGINEERING CONTROLS: Provide general and/or local 

exhaust ventilation. 

RECOMMENDATIONS FOR MANUFACTURING, 

COMMERCIAL BLENDING, AND PACKAGING 

WORKERS:

EYE/FACE PROTECTION: Use chemical goggles. Wear a 

face-shield, which allows use of chemical goggles, or wear a 

full-face respirator, to protect the face and eyes when there 

is any likelihood of splashes. Eye wash fountain should be 

located in the immediate work area.

SKIN PROTECTION: Use protective clothing, including 

neoprene gloves and impervious suit (such as SaranexTM

suit). Selection of specific items such as face shield, gloves, 

boots, apron, or full body suit will depend on operations. 

Remove contaminated clothing immediately, wash skin area 

with soap and water, and launder clothing before reuse. 

Contaminated leather items, such as shoes, belts, and 

watchbands, should be removed, destroyed and disposed of 

properly. Safety shower should be located in immediate 

work area. 

RESPIRATORY PROTECTION: Use a full-face air purifying 

respirator (APR) with organic vapor/acid gas and HEPA filter 

cartridges. 

APPLICATORS AND ALL OTHER HANDLERS: Refer to 

the product label for personal protective clothing and 

equipment. 

9. PHYSICAL AND CHEMICAL PROPERTIES: 

APPEARANCE: Off-white solid 

ODOR: Odorless

DENSITY: Not available 

MELTING POINT: 123-125°C

10. STABILITY AND REACTIVITY: 

STABILITY: (CONDITIONS TO AVOID) Information not 

available. 

INCOMPATIBILITY: (SPECIFIC MATERIALS TO AVOID)

Information not available. 

HAZARDOUS DECOMPOSITION PRODUCTS: If product 

is involved in a fire, evacuate area and keep non-emergency 

personal out of the area. May emit toxic fumes. 

HAZARDOUS POLYMERIZATION: Not expected to occur. 

11. TOXICOLOGICAL INFORMATION: 

POTENTIAL HEALTH EFFECTS: This section includes 

possible adverse effects, which could occur if this material is 

not handled in the recommended manner.

EYE: Based on similar material, 3,5,6-trichloropyridine 

carboxylic acid: May cause severe irritation with corneal 

injury, which may result in permanent impairment of vision, 

even blindness. Chemical burns may occur. 

SKIN: Based on similar material, 3,5,6-trichloropyridine 

carboxylic acid: Essentially nonirritating to skin. May cause 

more severe response if skin is damp. The dermal LD50 has 

not been determined.

INGESTION: Based on similar material, 3,5,6-

trichloropyridine carboxylic acid which has an oral LD50 

(female rat) > 2000 mg/kg. Moderate to low toxicity if 

swallowed. Small amounts swallowed incidental to normal 

handling operations are not likely to cause serious injury; 

however, swallowing larger amounts may cause injury. The 

oral LD50 has not been determined for this product. 
RESEARCH SAMPLE SAFETY DATA SHEET 

PRODUCT NAME: 4,5,6-Trichloropyridine-2-carboxylic 

acid 

Effective Date: 25-Sep-14

3 

INHALATION: Brief exposure to dust is not likely to be 

hazardous. Dust may cause irritation of upper respiratory 

tract (nose and throat). 

SYSTEMIC (OTHER TARGET ORGAN) EFFECTS: No 

relevant information available. 

CANCER INFORMATION: No relevant information 

available. 

TERATOLOGY (BIRTH DEFECTS): No relevant 

information available. 

REPRODUCTIVE EFFECTS: No relevant information 

available. 

MUTAGENICITY: No relevant information available. 

12. ECOLOGICAL INFORMATION: 

Information for similar material 3,5,6-trichloropyridine 

carboxylic acid: 

Persistence and Degradability

Theoretical Oxygen Demand: 0.85 mg/mg 

Mobility in soil 

Partition coefficient, soil organic carbon/water (Koc): 

64 Estimated.

Henry's Law Constant (H): 3.54E-09 atm*m3/mole; 25 

°C Estimated. 

Toxicity

Material is practically non-toxic to aquatic organisms on 

an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the 

most sensitive species tested). 

Fish Acute & Prolonged Toxicity 

LC50, rainbow trout (Oncorhynchus mykiss), 96 h: > 100 

mg/l

Aquatic Invertebrate Acute Toxicity 

LC50, water flea Daphnia magna, 48 h: > 100 mg/l

EC50, water flea Daphnia magna, 48 h, immobilization: > 

100 mg/l

13. DISPOSAL CONSIDERATIONS: 

DISPOSAL METHOD: If wastes and/or containers cannot 

be disposed of according to the product label directions, 

disposal of this material must be in accordance with your 

local or area regulatory authorities. 

This information presented below only applies to the 

material as supplied. The identification based on 

characteristic(s) or listing may not apply if the material has 

been used or otherwise contaminated. It is the responsibility 

of the waste generator to determine the toxicity and physical 

properties of the material generated to determine the proper 

waste identification and disposal methods in compliance 

with applicable regulations. 

If the material as supplied becomes a waste, follow all 

applicable regional, national and local laws and regulations. 

14. TRANSPORT INFORMATION: 

For 35 grams or less: 

DOT Non-bulk: NOT REGULATED 

IMDG: NOT REGULATED 

IATA/ICAO: NOT REGULATED 

15. REGULATORY INFORMATION: 

NOTICE: The information herein is presented in good faith 

and believed to be accurate as of the effective date shown 

above. However, no warranty, express or implied, is given. 

Regulatory requirements are subject to change and may 

differ from one location to another; it is the buyer’s 

responsibility to ensure that its activities comply with federal, 

state or provincial, and local laws. The following specific 

information is made for the purpose of complying with 

numerous federal, state or provincial, and local laws and 

regulations. 

U.S. REGULATIONS

SARA 313 INFORMATION: To the best of our knowledge, 

this product contains no chemical subject to SARA Title III 

Section 313 supplier notification requirements. 

SARA HAZARD CATEGORY: This product has been 

reviewed according to the EPA “Hazard Categories” 

promulgated under Section 311 and 312 of the Superfund 

Amendment and Reauthorization Act of 1986 (SARA Title 
RESEARCH SAMPLE SAFETY DATA SHEET 

PRODUCT NAME: 4,5,6-Trichloropyridine-2-carboxylic 

acid 

Effective Date: 25-Sep-14

4 

III) and is considered, under applicable definitions, to meet 

the following categories: 

An immediate health hazard 

A delayed health hazard 

TOXIC SUBSTANCES CONTROL ACT (TSCA): This 

product contains chemical substance(s) not on the TSCA 

Inventory. It may be used for research and development 

purposes only and only under the supervision of a 

technically qualified individual. All persons engaged in 

research and development with this product must be 

informed of the hazard information in this Research Sample 

Safety Data Sheet (RSSDS). 

STATE RIGHT-TO-KNOW: This product is not known to 

contain any substances subject to the disclosure 

requirements of Pennsylvania 

OSHA HAZARD COMMUNICATION STANDARD: This 

product is a “Hazardous Chemical” as defined by the OSHA 

Hazard Communication Standard, 29 CFR 1910.1200. 

16. OTHER INFORMATION: 

DSSDS STATUS: Revised Sections: 3, 8, 15

 Replaces DSSDS Dated: 01-Aug-14

The Information Herein Is Given In Good Faith, But No 

Warranty, Express or Implied, Is Made. Consult 

 for Further Information.