# RESEARCH SAMPLE SAFETY DATA SHEET

PRODUCT NAME : 4,5,6

- T ri chloro p yridine

- 2

- c arboxylic
acid Effective Date: 25

- Sep

- 14

1 1. PRODUCT AND COMPANY IDENTIFICATION:

PRODUCT: 4,5,6 -Trichloropyridine-2-carboxylic acid

COMPANY IDENTIFICATION:

2. HAZARDOUS IDENTIFICATIONS:

EMERGENCY OVERVIEW Off-white odorless solid

. May be harmful if inhaled, absorbed through skin or swallowed. Risk of serious damage to eyes. May cause skin irritation. Evacuate area. Keep upwind of spill. Toxic fumes may be released in fire situations. EMERGENCY PHONE NUMBER: 800

- 992

- 5994

3. COMPOSITION/INFORMATION ON INGREDIENTS:

Component CAS/DR Number W/W% 4,5,6

- Trichloropyridine

2

- carboxylic acid 496849

- 77

- 5 85

- 95 %

Water 7732

- 18

- 5 5

- 15%

4. FIRST AID:

EYE: Wash immediately and continuously with flowing water for at least 30 minutes. Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist.

SKIN: Remove material from skin immediately by washing with soap and plenty of water. Remove contaminated clothing and shoes while washing. Seek medical attention if irritation persists. Wash clothing before reuse. Discard items, which cannot be decontaminated, including leather articles such as shoes, belts, and watchbands. INGESTION: Call a treatment center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control or doctor. Never give anything by mouth to an unconscious person.

INHALATION: Move person to fresh air. If person is not breathing, call an emergency responder or an ambulance, and then give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask etc). Call a poison control center or doctor for treatment advice.

NOTE TO PHYSICIAN: No specific antidote. Treatment of exposure should be based on judgment of the physician in response to reactions of the patient.

5. FIRE FIGHTING MEASURES:

FLASH POINT : Not applicable MET HOD USED : Not applicable

FLAMMABLE LIMITS LFL: Not determined UFL: Not determined

EXTINGUISHING MEDIA : Foam, CO 2 , Dry chemical

FIRE AND EXPLOSION HAZARDS : Foam fire extinguishing system is preferred because uncontrolled water can spread possible contamination. Toxic irritating gases may be formed under fire conditions. Combustion products can include and are not limited to: Carbon monoxide. Carbon dioxide. Nitrogen oxides. Hydrogen chloride.

FIRE-FIGHTING EQUIPMENT : Use positive-pressure, selfcontained breathing apparatus and full protective equipment.

6. ACCIDENTAL RELEASE MEASURES:

ACTION TO TAKE FOR SPILLS : For sol id or powder substances: sweep up small spills and place in a suitable container for reuse or disposal. Wash exposed body areas thoroughly after handling. Report large spills to on 800- 992

- 5994.

# RESEARCH SAMPLE SAFETY DATA SHEET

PRODUCT NAME : 4,5,6

- T ri chloro p yridine

- 2

- c arboxylic
acid Effective Date: 25

- Sep

- 14

2 7. HANDLING AND STORAGE:

PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE : Keep out of reach of children. Do not swallow. Avoid contact with eyes, skin, and clothing. Avoid breathing vapors, spray mist or dusts. Handle in ventilated area. Wash thoroughly with soap and water after handling and before eating, chewing gum, using tobacco, using the toilet or smoking. Keep away from food, feedstuffs, and water supplies. Store in the original containers.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION:
These precautions are suggested for conditions where a potential for exposure exists. Emergency conditions may require additional precautions.

EXPOSURE GUIDELINES : None established.

ENGINE ERING CONTROLS : Provide general and/or local exhaust ventilation.

RECOMMENDATIONS FOR MANUFACTURING, COMMERCIAL BLENDING, AND PACKAGING WORKERS:

EYE/FACE PROTECTION: Use chemical goggles. Wear a face-shield, which allows use of chemical goggles, or wear a full-face respirator, to protect the face and eyes when there is any likelihood of splashes. Eye wash fountain should be located in the immediate work area.

SKIN PROTECTION: Use protective clothing, including neoprene gloves and impervious suit (such as Saranex TM suit). Selection of specific items such as face shield, gloves, boots, apron, or full body suit will depend on operations. Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing before reuse. Contaminated leather items, such as shoes, belts, and watchbands, should be removed, destroyed and disposed of properly. Safety shower should be located in immediate work area.

RESPIRATORY PROTECTION: Use a full-face air purifying respirator ( APR ) with organic vapor/acid gas and HEPA filter cartridges. APPLICATORS AND ALL OTHER HANDLERS: Refer to the product label for personal protective clothing and equipment.

9. PHYSICAL AND CHEMICAL PROPERTIES:

APPEARANCE : Off-white solid ODOR: Odorle ss DENSITY: Not available MELTING POINT: 123

- 125 °C

10. STABILITY AND REACTIVITY:

STABILITY: (CONDITIONS TO AVOID) Information not available.

INCOMPATIBILITY: (SPECIFIC MATERIALS TO AVOID) Information not available.

HAZARDOUS DECOMPOSITION PRODUCTS : If product is involved in a fire, evacuate area and keep non-emergency personal out of the area. May emit toxic fumes.

HAZARDOUS POLYMERIZATION : Not expected to occur.

11. TOXICOLOGICAL INFORMATION:

POTENTIAL HEALTH EFFECTS: This section includes possible adverse effects, which could occur if this material is not handled in the recommended manner.

EYE : Based on similar material, 3,5,6 -tri chloropyridine carboxylic acid: May cause severe irritation with corneal injury, which may result in permanent impairment of vision, even blindness. Chemical burns may occur.

SKIN: B ased on similar material, 3,5,6 -trichloropyridine carboxylic acid: Essentially nonirritating to skin. May cause

more sev ere response if skin is damp. The dermal LD 50 has not been determined.

INGESTION : Based on similar material

, 3,5,6

- tr ichl oropyridine carboxylic acid which has an oral LD 50 (female rat) > 2000 mg/kg. Moderate to low toxicity if swallowed. Small amounts swallowed incidental to normal handling operati ons are not likely to cause serious injury; however, swallowing larger amounts may cause injury. The oral LD 50 has not been determined for this product.

# RESEARCH SAMPLE SAFETY DATA SHEET

PRODUCT NAME : 4,5,6

- T ri chloro p yridine

- 2

- c arboxylic
acid Effective Date: 25

- Sep

- 14

3 INHALATION : Brief exposure to dust is not likely to be hazardous. Dust may cause irritation of upper respiratory tract (nose and throat).

SYSTEMIC (OTHER TARGET ORGAN) EFFECTS : No relevant information available.

CANCER INFORMATION: No relevant information available.

TERATOLOGY (BIRTH DEFECTS): No relevant information available.

REPRODUCTIVE EFFECTS: No relevant information available.

MUTAGENICITY : No relevant information available.

12. ECOLOGICAL INFORMATION:

Information for similar material 3,5,6-trichloropyridine carboxylic acid:

Persistence and Degradability Theoretical Oxygen Demand: 0.85 mg/mg

Mobility in soil Partition coefficient, soil organic carbon/water (Koc): 64 Estimated. Henry's Law Constant (H): 3.54E

- 09 atm*m3/mole ; 25 °C Estimated.

Toxic ity Material is practically non-toxic to aquatic organisms on an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested).

Fish Acut e & Prolonged Toxicity LC50

, rainbow trout (Oncorhynchus mykiss)

, 96 h : > 100 mg/l Aq uatic Invertebrate Acute Toxicity LC50

, water flea Daphnia magna

, 48 h : > 100 mg/l EC50

, w ater flea Daphnia mag na
, 48 h

, immobilization : > 100 mg/l

13. DISPOSAL CONSIDERATIONS:

DISPOSAL METHOD: If wastes and/or containers cannot be disposed of according to the product label directions, disposal of this material must be in accordance with your local or area regulatory authorities.

This information presented below only applies to the material as supplied. The identification based on characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations.

If the material as supplied becomes a waste, follow all applicable regional, national and local laws and regulations.

14. TRANSPORT INFORMATION:

For 35 grams or less:

DOT Non-bulk: NOT REGULATED

IMDG: NOT REGULATED

IATA/ICAO: NOT REGULATED

15. REGULATORY INFORMATION:

NOTICE: The information herein is presented in good faith and bel ieved to be accurate as of the effective date shown above. However, no warranty, express or implied, is given. Regulatory requirements are subject to change and may differ from one location to another; it is the buyer’s responsibility to ensure that its activities comply with federal, state or provincial, and local laws. The following specific information is made for the purpose of complying with numerous federal, state or provincial, and local laws and regulations.

U.S. REGULATIONS

SARA 313 INFORMATION: To the best of our knowledge, this product contains no chemical subject to SARA Title III Section 313 supplier notification requirements.

SARA HAZARD CATEGORY: This product has been reviewed according to the EPA “Hazard Categories” promulgated under Section 311 and 312 of the Superfund Amendment and Reauthorization Act of 1986 (SARA Title

# RESEARCH SAMPLE SAFETY DATA SHEET

PRODUCT NAME : 4,5,6

- T ri chloro p yridine

- 2

- c arboxylic
acid Effective Date: 25

- Sep

- 14

4 III) and is considered, under applicable definitions, to meet the following categories:

An immediate health hazard A delayed health hazard

TOXIC SUBSTANCES CONTROL ACT (TSCA): This product contains chemical substance(s) not on the TSCA Inventory. It may be used for research and development purposes only and only under the supervision of a technically qualified individual. All persons engaged in research and development with this product must be informed of the hazard information in this Research Sample Safety Data Sheet (RSSDS).

STATE RIGHT- TO -KNOW: This product is not known to contain any substances subject to the disclosure requirements of Pennsylvania

OSHA HAZARD COMMUNICATION STANDARD: This product is a “Hazardous Chemical” as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200.

16. OTHER INFORMATION:

DSSDS STATUS : Revised Sections: 3 , 8, 15

Replac es DSSDS Dated: 01 -Aug- 14

The Information Herein Is Given In Good Faith, But No Warranty, Express or Implied, Is Made. Consult

for Further Information.