SYNTHETIC BLOOD INTERNATIONAL, INC.

STOCK OPTION AGREEMENT

THIS STOCK OPTION AGREEMENT is made this 6th day of June 2001 by and between Synthetic Blood International, Inc, a
corporation formed under the laws of the State of New Jersey (the "Company"), and Robert Skalnik, a citizen and resident of the
State of California (the "Optionee").

WITNESSETH:

WHEREAS, the Optionee is a valued executive, key employee or advisor of the Company, and

WHEREAS, the Company considered it desirable and in its best interest that the Optionee be provided an inducement to acquire
an ownership interest in the Company and an additional incentive to advance the interest of the Company through grant of an
option to purchase shares of the $0.01 par value common stock of the Company.

NOW THEREFORE, in consideration of the premises contained herein, it is agreed as follows:

( 1 ) Grant of Option. Subject to the terms and conditions contained herein, the Company hereby grants the Optionee the right,
privilege and option (the "Option") to purchase Sixty two hundred and fifty (6,250) shares of the $0.01 par value common stock
of the Company at a price of one cent ($0.01) per share.

(2) Term and Vesting of Option. The term of the Option shall be for a period of five (5) years (the "Term") from the date of this
Agreement and, subject to the terms and provisions hereof, the Option shall be fully vested and may be exercised in whole or in
part with respect to all or any portion of the shares to which it related.

(3) Method of Exercise The Option shall be exercised by the transmittal of written notice thereof to the Company at its principal
place of business. The notice' shall include the Optionee's designation of the number of shares to be purchased and Optionee's
check in payment of the purchase price. Upon receipt of such notice and negotiation of said check, the Company shall deliver to
the Optionee a certificate representing the shares purchased, provided that if any law or regulation requires the Company to take
any action with respect to the shares specified in such notice before the issuance thereof, the date of delivery of the shares shall
be extended for the necessary period.

( 4 ) Termination of Option. Except as otherwise provided herein, the Option shall terminate upon the expiration of five (5)
years from the date of this Agreement.

(5) Right Prior to Exercise of Option. The Optionee shall have no rights as a stockholder with respect to the shares of stock
subject to the Option until the: exercise of his rights hereunder and the issuance and delivery to Optionee of a certificate or
certificates evidencing such shares.

( 6) Applicable Laws. The validity, construction, interpretation ,and enforceability of this Agreement and the capacity of the
parties shall be determined and governed by the laws of the State of California.

(7) Severability. The provisions of this Agreement are severable and if any one or more provisions may be determined to be
illegal or otherwise unenforceable, in whole or in part, the remaining provisions, and any partially unenforceable provision to
the extent enforceable in any jurisdiction, shall nevertheless be binding and enforceable.

(8) Waiver. The waiver by the Company of a breach of any provision of this Agreement by Optionee shall not operate or be
construed as a waiver of any subsequent breach by Optionee.

(9) Binding Effect. The provisions of this Agreement shall be binding upon the parties hereto, their successors and assigns,
including, without limitation, the estate of the Optionee and the executors, administrators or trustees of such estate and any
receiver, trustee in bankruptcy or representative of the creditors of the Optionee.

THIS STOCK OPTION AGREEMENT is hereby confirmed and executed as of this 6th day of June, 2001.

ATTEST:

SYNTHETIC BLOOD INTERNATIONAL, INC.

By:  Robert Nicora

President

OPTIONEE

Robert Skalnik